2,508 results match your criteria Oral diseases[Journal]


The fibroblast of radicular cyst facilitate osteoclastogenesis via the autocrine of Fibronectin containing extra domain A.

Oral Dis 2019 Feb 16. Epub 2019 Feb 16.

Department of Pathology, School& Hospital of Stomatology, Tongji University, Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Shanghai, China.

Objective: To investigate the alternative spliced isoforms of Fibronectin (FN) in the stroma of radicular cysts; and analyze the associations between these isoforms and the osteoclastogenic effects of fibroblasts.

Methods And Materials: The specimens of radicular cysts were stained with immunohistochemistry, and the associations between each FN isoform and clinical parameters were assessed. The fibroblasts isolated from cysts or jaw bone were cultured to induce the Trap+MNCs. Read More

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http://dx.doi.org/10.1111/odi.13064DOI Listing
February 2019

Autophagy-related Gene Expression Regulated by HIF-1α in Salivary Adenoid Cystic Carcinoma.

Oral Dis 2019 Feb 11. Epub 2019 Feb 11.

Department of Oral and Maxillofacial Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, 250012, China.

Objectives: Salivary adenoid cystic carcinoma (SACC) is one of the most common malignant salivary gland tumors. Our study aims to investigate whether hypoxia-induced autophagy was up-regulated in the progression of SACC.

Materials And Methods: We performed differentially expressed gene analysis, pathway enrichment analysis and then calculated the correlation analysis on GSE59701 and GSE28996 datasets. Read More

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http://dx.doi.org/10.1111/odi.13058DOI Listing
February 2019

Sex Hormone Replacement Therapy in Periodontology - A Systematic Review.

Oral Dis 2019 Feb 10. Epub 2019 Feb 10.

Department of Stomatology, Federal University of Paraná (UFPR), Curitiba, PR, Brazil.

Objective: To analyse whether sex hormone replacement therapy (HRT) improves periodontal parameters and dental implants osseointegration in humans.

Materials And Methods: Electronic databases and hand searches were performed from June to August 2018 in SciELO, LILACS and PubMed/Medline. Human observational and interventional studies that evaluated the following parameters were included: Clinical Attachment Loss (CAL), Probing Pocket Depth (PPD), Bleeding on Probing (BOP), Radiographic Bone Loss (RBL) or osseointegration. Read More

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http://dx.doi.org/10.1111/odi.13059DOI Listing
February 2019
1 Read

The Effects of Ozone Therapy on Periodontal Therapy: A Randomized Placebo-Controlled Clinical Trial.

Oral Dis 2019 Feb 10. Epub 2019 Feb 10.

Afyon Kocatepe University, Faculty of Dentistry, Department of Periodontology, Afyonkarahisar, Turkey.

Objectives: The aim of this randomized split-mouth clinical trial was to evaluate the effects of ozone therapy on clinical and biochemical parameters of moderate to severe generalized periodontitis patients after non-surgical periodontal therapy.

Methods: A total of 36 moderate to severe generalized periodontitis patients were included in the study. The patients were systemically healthy and 18 to 64 years of age. Read More

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http://dx.doi.org/10.1111/odi.13060DOI Listing
February 2019
1 Read

Role of mammary serine protease inhibitor on the inflammatory response in oral lichen planus.

Oral Dis 2019 Feb 9. Epub 2019 Feb 9.

Shanxi Medical University School and Hospital of Stomatology, Taiyuan, 030001, China.

Objectives: Oral lichen planus (OLP) is a chronic inflammatory condition with an unclear pathological mechanism. IκB kinase α (IKKα)-regulated mammary serine protease inhibitor (MASPIN) has been shown to mediate inflammation, particularly in cancers. Here, we explored the expression of MASPIN in OLP and its role in the inflammatory response. Read More

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http://doi.wiley.com/10.1111/odi.13054
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http://dx.doi.org/10.1111/odi.13054DOI Listing
February 2019
2 Reads

Oral health and associated factors among preschool children with special health care needs.

Oral Dis 2019 Feb 6. Epub 2019 Feb 6.

Periodontology and Public Health, Faculty of Dentistry, The University of Hong Kong, 2/F Prince Philip Dental Hospital, 34 Hospital Road, Hong Kong SAR, China.

Objective: To investigate the oral health status and associated factors among preschool children with special health care needs.

Subjects And Methods: This was designed as a cross-sectional study. Dental examination were provided to 383 children at Special Child Care Centres. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/odi.13057
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http://dx.doi.org/10.1111/odi.13057DOI Listing
February 2019
4 Reads

Patient-derived xenografts (PDX) of a case of ameloblastic fibrodentinoma.

Oral Dis 2019 Feb 5. Epub 2019 Feb 5.

Departament of Pathology, Biological Science Institute, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brazil.

Ameloblastic Fibrodentinoma (AFD) is a benign odontogenic tumour of unclear pathogenesis. It is usually diagnosed before the age of 20 years and treatment is conservative surgery, with occasional segmental resection (Philipsen et al., 1997, Chrcanovic & Gomez, 2017). Read More

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http://dx.doi.org/10.1111/odi.13056DOI Listing
February 2019
1 Read

Zoledronate Treatment Duration Is Linked to Bisphosphonate-Related ONJ Prevalence in Rice Rats with Generalized Periodontitis.

Oral Dis 2019 Feb 3. Epub 2019 Feb 3.

Department of Physiological Sciences, University of Florida, Gainesville, FL.

Objectives: To determine the extent that zoledronate (ZOL) dose and duration is associated with bisphosphonate-related osteonecrosis of the jaw (BRONJ) prevalence in rice rats with generalized periodontitis (PD); characterize structural and tissue-level features of BRONJ-like lesions in this model; and examine the specific anti-resorptive role of ZOL in BRONJ.

Materials And Methods: Rice rats (n=228) consumed high-sucrose-casein diet to enhance generalized PD. Groups of rats received 0, 8, 20, 50 or 125μg/kg IV ZOL/4wks encompassing osteoporosis and oncology ZOL doses. Read More

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http://dx.doi.org/10.1111/odi.13052DOI Listing
February 2019
1 Read

The reciprocal association between diabetes mellitus and erosive oral lichen planus.

Oral Dis 2019 Jan 30. Epub 2019 Jan 30.

State Key Laboratory of Oral Diseases, Department of Oral Medicine, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, P.R. China.

We read with interest the article by Otero Rey E. M. and colleagues that was recently published in Oral Diseases (Otero Rey E. Read More

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http://dx.doi.org/10.1111/odi.13050DOI Listing
January 2019

Perioperative changes in knowledge and attitude towards oral health by oral health education.

Oral Dis 2019 Jan 30. Epub 2019 Jan 30.

Division of Oral Science for Health Promotion, Niigata University.

Objectives: Perioperative oral health care can prevent postoperative complications, but it is also important to maintain oral health afterwards to avoid later adverse events. This study examined 1) the relationship between knowledge and attitude towards oral health (KAOH) and oral/periodontal status (OPS) in patients receiving surgery, and 2) the changes in KAOH by perioperative oral health care and education.

Methods: Patients receiving surgery who visited our hospital's dental clinic beforehand were prospectively recruited. Read More

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http://doi.wiley.com/10.1111/odi.13048
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http://dx.doi.org/10.1111/odi.13048DOI Listing
January 2019
2 Reads

Preoperative circulating platelet, neutrophil, and lymphocyte counts predict survival in oral cancer.

Oral Dis 2019 Jan 29. Epub 2019 Jan 29.

Jiangsu Key Laboratory of Oral Disease, Nanjing Medical University, Jiangsu, China.

Objective: Circulating immune-inflammatory cells have been increasingly recognized as robust prognostic biomarkers in cancer. Here, we sought to evaluate the prognostic values of preoperative peripheral platelet, neutrophil, lymphocyte quantitation in patients with primary oral squamous cell carcinoma (OSCC).

Materials And Methods: A total number of 309 patients with primary OSCC surgically treated at our institutions were retrospectively included. Read More

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http://dx.doi.org/10.1111/odi.13049DOI Listing
January 2019
2.427 Impact Factor

Bacteremia after professional mechanical plaque removal in patients with chronic periodontitis.

Oral Dis 2019 Jan 25. Epub 2019 Jan 25.

Institute of Medical Microbiology and Epidemiology on Infectious Diseases in Leipzig, Germany.

Objective: The aim of this study was to investigate the characteristics of bacteremia caused by professional mechanical plaque removal (PMPR) in 2 groups of patients with generalized moderate chronic periodontitis.

Material And Methods: Venous blood samples were taken at multiple time points for one hour following PMPR in fifty patients with generalized moderate chronic periodontitis. Subjects consisted of two groups, one group was receiving supportive periodontal therapy (SPT, n = 25) and the other group was receiving initial periodontal therapy (IPT, n = 25). Read More

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http://dx.doi.org/10.1111/odi.13047DOI Listing
January 2019
2 Reads

The role of autophagy in the pathogenesis of periodontal disease.

Oral Dis 2019 Jan 23. Epub 2019 Jan 23.

Department of Stomatology, Tongji Hospital of Tongji Medical College of Huazhong, University of Science and Technology, Wuhan, China.

Periodontal disease is a chronic inflammatory disease leading to destruction of periodontal tissues. As a local inflammation, periodontopathic bacterium, pro-inflammatory mediators, and local immune response play pivotal role in the progress of periodontal disease. Besides, cigarette smoke has long been associated with periodontal disease and tooth loss. Read More

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http://doi.wiley.com/10.1111/odi.13045
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http://dx.doi.org/10.1111/odi.13045DOI Listing
January 2019
6 Reads

Systemic comorbidities are associated with medication-related osteonecrosis of the jaws: case-control study.

Oral Dis 2019 Jan 23. Epub 2019 Jan 23.

Menzies Health Institute Queensland, Griffith University, Southport, Queensland, 4222, Australia.

Objectives: Medication-related osteonecrosis of the jaws (MRONJ) is a serious condition developed in up to 15% of patients who take antiresorptive medications. Its underlying pathogenesis remains unclear. The association between systemic comorbidities and MRONJ was investigated. Read More

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http://dx.doi.org/10.1111/odi.13046DOI Listing
January 2019
1 Read

Azithromycin and erythromycin susceptibility and macrolide resistance genes in Prevotella from patients with periodontal disease.

Oral Dis 2019 Jan 22. Epub 2019 Jan 22.

Department of Microbiology, Dentaid Research Center, Cerdanyola del Vallès, Spain.

Objectives: To study oral Prevotella spp. isolated from patients with chronic periodontitis, to determine their susceptibility to azithromycin and erythromycin and to screen the presence of macrolide resistance genes therein.

Material And Methods: Isolates with a Prevotella-like morphology were obtained from subgingival samples of 52 patients with chronic periodontitis. Read More

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http://dx.doi.org/10.1111/odi.13043DOI Listing
January 2019

Influence of Porphyromonas gingivalis in gut microbiota of streptozotocin-induced diabetic mice.

Oral Dis 2019 Jan 22. Epub 2019 Jan 22.

Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan.

Objectives: Increasing evidence suggests that periodontitis can exacerbate diabetes, and gut bacterial dysbiosis appears to be linked with the diabetic condition. The present study examined the effects of oral administration of the periodontopathic bacterium, Porphyromonas gingivalis, on the gut microbiota and systemic conditions in streptozotocin-induced diabetic mice.

Materials And Methods: Diabetes was induced by streptozotocin injection in C57BL/6J male mice (STZ). Read More

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http://dx.doi.org/10.1111/odi.13044DOI Listing
January 2019
2.427 Impact Factor

Overexpression of ephrinB2 in stem cells from apical papilla accelerates angiogenesis.

Oral Dis 2019 Jan 22. Epub 2019 Jan 22.

Endodontology, Faculty of Dentistry, The University of Hong Kong, Hong Kong, Hong Kong.

Objectives: We aimed to accelerate angiogenesis in pulp regeneration by modulating ephrinB2 expression in stem cells from apical papilla (SCAPs).

Materials And Methods: Stem cells from apical papilla were transducted with ephrinB2-lentiviral expression vector (ephrinB2-SCAPs) in experimental group and green fluorescent protein (GFP-SCAPs) in control group. The transduction efficiency was confirmed by real-time PCR and Western blot assays. Read More

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http://dx.doi.org/10.1111/odi.13042DOI Listing
January 2019
3 Reads
2.427 Impact Factor

World Workshop on Oral Medicine VII: Biomarkers predicting lymphoma in the salivary glands of patients with Sjögren's syndrome. A systematic review.

Oral Dis 2019 Jan 21. Epub 2019 Jan 21.

Department of Oral and Maxillofacial Surgery, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.

Objective: To conduct a systematic review of studies exploring potential biomarkers for development, course and efficacy of treatment of lymphomas in salivary glands of patients with Sjögren's syndrome.

Material And Methods: Eligible studies were identified through a comprehensive search of two databases, i.e. Read More

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http://dx.doi.org/10.1111/odi.13041DOI Listing
January 2019
2 Reads
2.427 Impact Factor

Periodontal status and clinical outcomes in kidney transplant recipients: A systematic review.

Oral Dis 2019 Jan 20. Epub 2019 Jan 20.

Dentistry Graduate Program, Federal University of Maranhão, São Luís, Maranhão, Brazil.

Objective: The aim of this systematic review was to identify clinical outcomes following kidney transplantation associated with periodontal status.

Material And Methods: A systematic review was conducted and included cross-sectional, case-control, or cohort studies published until August 2018 from PubMed/MEDLINE, Scopus, Science Direct, and CENTRAL. The research was carried out using the following descriptors: "kidney transplantation," "chronic renal failure," "periodontal diseases," "periodontitis," "chronic periodontitis," "gingival hyperplasia," and "gingivitis. Read More

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http://doi.wiley.com/10.1111/odi.13040
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http://dx.doi.org/10.1111/odi.13040DOI Listing
January 2019
2 Reads

Diversity of the oral microbiome between dentate and edentulous individuals.

Oral Dis 2019 Jan 18. Epub 2019 Jan 18.

Department of Oral Medicine and Diagnostic Sciences, College of Dentistry, University of Illinois at Chicago, Chicago, Illinois.

Background: Measurement of saliva microbes is promoted as a way to detect oral and systemic disease, yet there is a multitude of factors that affect the oral microbiome. The salivary microbiome is influenced by oral biofilm of shedding (epithelial) and non-shedding (tooth) surfaces.

Methods: To gauge the ability of salivary microbial analytics to distinguish between edentulous and dentate oral conditions, we looked for differences in the saliva microbiome of subjects with and without teeth. Read More

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http://doi.wiley.com/10.1111/odi.13039
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http://dx.doi.org/10.1111/odi.13039DOI Listing
January 2019
4 Reads

Transcranial Direct Current Stimulation (tDCS) and trigeminal pain: a pre-clinical study.

Oral Dis 2019 Jan 12. Epub 2019 Jan 12.

Pharmacology of Pain and Neuromodulation Laboratory: Preclinical Researches, Department of Pharmacology, Institute of Basic Health Sciences (ICBS), Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, 90050-170, Brazil.

Objective: Our objective was to evaluate the tDCS effect on facial allodynia induced by chronic constriction of the infraorbital nerve (CCI-ION) and on the brainstem levels of TNF-α, NGF, IL-10 and, serum LDH in rats.

Methods: Rats were exposed to the CCI-ION model. Facial allodynia was assessed by Von Frey filaments test at baseline, 3, 7, 10 and 14 days post-surgery and24h and 7 days after the bimodal tDCS sessions for 20 min/day/8 days. Read More

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http://dx.doi.org/10.1111/odi.13038DOI Listing
January 2019
1 Read
2.427 Impact Factor

Synergistic effect of hyperbaric oxygen therapy with PTH [1-34] on calvarial bone graft in irradiated rat.

Oral Dis 2019 Jan 11. Epub 2019 Jan 11.

Department of Periodontology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, Korea.

Objective: To determine the synergistic effect of parathyroid hormone (PTH) [1-34] in combination with hyperbaric oxygen (HBO) on bone graft in a rat calvarial bone defect model under impaired osteogenic conditions.

Materials And Methods: Twenty-four rats were divided into three groups. Localized radiation with a single 12 Gy dose was administered to the calvaria. Read More

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http://doi.wiley.com/10.1111/odi.13037
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http://dx.doi.org/10.1111/odi.13037DOI Listing
January 2019
6 Reads

MAL-PDT inhibits oral precancerous cells and lesions via autophagic cell death.

Oral Dis 2019 Jan 8. Epub 2019 Jan 8.

Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.

Background: Oral cancer is a common cancer with a high mortality rate. While surgery is the most effective treatment for oral cancer, it frequently causes deformity and dysfunction in the orofacial region. In this study, methyl aminolevulinate photodynamic therapy (MAL-PDT) as a prevention tool against progression of precancerous lesion to oral cancer was explored. Read More

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http://dx.doi.org/10.1111/odi.13036DOI Listing
January 2019

Extensive erosion instead of leukoplakia can be the oral manifestation of dyskeratosis congenita.

Oral Dis 2019 Jan 8. Epub 2019 Jan 8.

State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China.

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http://dx.doi.org/10.1111/odi.13035DOI Listing
January 2019

Mechanical stress induced S100A7 expression in human dental pulp cells to augment osteoclast differentiation.

Oral Dis 2019 Jan 7. Epub 2019 Jan 7.

Oral Biology Research Center, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand.

Objectives: Mechanical injury of dental pulp leads to root resorption by osteoclasts/odontoclasts. S100 proteins have been demonstrated to be involved in inflammatory processes and bone remodeling. This study aimed to investigate the effect of mechanical stress on S100A7 expression by human dental pulp cells (HDPCs) and the effect of S100A7 proteins on osteoclast differentiation. Read More

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http://dx.doi.org/10.1111/odi.13033DOI Listing
January 2019

Six-month clinical outcomes of non-surgical periodontal treatment with antibiotics on apoptosis markers in aggressive periodontitis.

Oral Dis 2019 Jan 6. Epub 2019 Jan 6.

Department of Orofacial Sciences, School of Dentistry, University of California, California.

Objective: Extrinsic and intrinsic pathways of apoptosis are involved in generalized aggressive periodontitis (GAgP). The aim of this study was to evaluate 6-month clinical outcomes relative to apoptosis of one-stage full-mouth disinfection (OSFMD) and systemic antibiotics (SA) in the treatment of GAgP.

Methods: Twenty-six patients with GAgP were included in this prospective follow-up intervention study. Read More

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http://dx.doi.org/10.1111/odi.13032DOI Listing
January 2019

Curcumin, a turmeric extract, for oral lichen planus: A systematic review.

Oral Dis 2019 Jan 7. Epub 2019 Jan 7.

University of Connecticut School Dental Medicine, Farmington, Connecticut.

Objective: Conduct a PROSPERO registered (CRD42018105227) systematic review of the efficacy of curcumin in the treatment of oral lichen planus (OLP).

Data Sources: Medline from the earliest possible date to the present (December 18, 2018) using the terms "turmeric" OR "curcumin" OR "curcuma" AND "oral lichen planus".

Study Selection And Data Extraction: Studies assessing patient outcomes in OLP. Read More

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http://doi.wiley.com/10.1111/odi.13034
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http://dx.doi.org/10.1111/odi.13034DOI Listing
January 2019
15 Reads

Understanding the pathophysiology behind chairside diagnostics and genetic testing for IL-1 and IL-6.

Oral Dis 2019 Jan 6. Epub 2019 Jan 6.

Department of Periodontology, Creighton University School of Dentistry, Omaha, Nebraska.

In order for chairside diagnostic testing to make an impact on dental therapy, practitioners require a better understanding of genetic mutations contributing to the pathophysiology of periodontal disease. Commensal and pathogenic bacterial colonization in oral cavity tissues produces a cascade of proinflammatory signaling pathways ultimately detrimental to host tissues. Resolving inflammation is a multifactorial process involving the downregulation of proinflammatory cytokines while allowing commensal bacterial levels to return to normal. Read More

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http://dx.doi.org/10.1111/odi.13030DOI Listing
January 2019
14 Reads

Global incidence and profile of ameloblastoma: A systematic review and meta-analysis.

Oral Dis 2019 Jan 6. Epub 2019 Jan 6.

Department of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands.

Objectives: To evaluate the global incidence of ameloblastoma and to provide a profile of ameloblastoma patients.

Material And Methods: A systematic review and meta-analysis was conducted. Searches were performed in PubMed, EMBASE, SCOPUS, and Web of Science for articles published from 1969 to 2018 for the global incidence and from 1995 to 2018 for the profile of ameloblastoma patients. Read More

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http://doi.wiley.com/10.1111/odi.13031
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http://dx.doi.org/10.1111/odi.13031DOI Listing
January 2019
3 Reads

Female undergraduate dental students may present higher depressive symptoms: A systematic review.

Oral Dis 2019 Jan 2. Epub 2019 Jan 2.

Department of Periodontology, Federal University of Pelotas, Pelotas, Brazil.

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http://dx.doi.org/10.1111/odi.13029DOI Listing
January 2019

Sense of Coherence mediates the association between temporomandibular disorders and quality of life.

Oral Dis 2018 Dec 28. Epub 2018 Dec 28.

Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas, Pelotas, Brazil.

Objective: This study aimed to evaluate whether sense of coherence (SOC) mediates the association between temporomandibular disorders (TMD) and oral health-related quality of life (OHRQoL) and general quality of life (QoL) in Brazilian elders.

Methods: Informations on sociodemographic, psychological, and presence or absence of temporomandibular disorders (TMD) were collected by trained dentists among non-institutionalized elders (n = 110). OHRQoL was measured with the Oral Health Impact Profile (OHIP-14) and QoL using the WHOQOL-BREF. Read More

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http://doi.wiley.com/10.1111/odi.13027
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http://dx.doi.org/10.1111/odi.13027DOI Listing
December 2018
5 Reads

Impact of oral potentially malignant disorder subtypes on all-cause and cause-specific mortality in males.

Oral Dis 2018 Dec 27. Epub 2018 Dec 27.

School of Oral Hygiene, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.

Objectives: To quantify the effect of oral potentially malignant disorder (OPMD) subtypes on mortality from oral cancer and type 2 diabetes among areca nut chewers and/or cigarette smokers.

Materials And Methods: A retrospective cohort design was devised to follow 14,749 men attending community-based screening program for oral cancer between 1998 and 2000 and followed until 2010. The Cox proportional hazards regression model was applied to assess the effect of OPMD on death. Read More

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http://dx.doi.org/10.1111/odi.13028DOI Listing
December 2018

Periodontal awareness and what it actually means: A cross-sectional study.

Oral Dis 2018 Dec 24. Epub 2018 Dec 24.

Department of Surgery and Medical-Surgical Specialities, School of Medicine and Dentistry, University of Santiago de Compostela, Santiago de Compostela, Spain.

Objectives: To assess periodontal awareness among laypersons, to characterize the very aware of periodontitis and to disclose whether high awareness implies sufficient periodontal knowledge.

Subjects And Methods: Cross-sectional study on laypersons randomly selected by quota sampling from March 2015 to June 2016. The questionnaire of periodontal awareness included aspects of aetiology, risk factors, signs and symptoms, related risks, prevention, treatment and related attitudes. Read More

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http://doi.wiley.com/10.1111/odi.13026
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http://dx.doi.org/10.1111/odi.13026DOI Listing
December 2018
5 Reads

International symposium defines the future role of oral physicians.

Oral Dis 2019 Mar 11;25(2):634-635. Epub 2019 Jan 11.

Hiyoshi Oral Health Clinics, Sakata, Japan.

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http://doi.wiley.com/10.1111/odi.13025
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http://dx.doi.org/10.1111/odi.13025DOI Listing
March 2019
4 Reads

Non-syndromic cleft lip with or without palate susceptible loci is associated with tooth agenesis.

Oral Dis 2018 Dec 21. Epub 2018 Dec 21.

Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.

Objective: Non-syndromic tooth agenesis (NSTA) may share common genetic factors with non-syndromic cleft lip with or without cleft palate (NSCL/P). Single-nucleotide polymorphisms (SNPs) were associated with individual's susceptibility to these anomalies. We selected five NSCL/P-associated SNPs from our previous genome-wide association study (GWAS) to test for the associations with NSTA. Read More

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http://dx.doi.org/10.1111/odi.13024DOI Listing
December 2018
3 Reads
2.427 Impact Factor

Symmetrical palatal fibromatosis: Five new cases and a review of the literature.

Oral Dis 2018 Dec 19. Epub 2018 Dec 19.

Department of Diagnostic & Biomedical Sciences, University of Texas School of Dentistry, Houston, Texas.

Objective: To present five cases of symmetrical palatal fibromatosis (SPF), a lesion reported very rarely in the English language literature, under more than a dozen different names, and to recommend the most appropriate name.

Methods: Five SPF cases are characterized with a literature review.

Results: Three females and two males, aged 20-39 years, presented with bilateral, symmetrical, asymptomatic, sessile, moderately firm, or soft (n = 2) masses of the lateral posterior hard palate; two were isolated to the tuberosities. Read More

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http://dx.doi.org/10.1111/odi.13021DOI Listing
December 2018

Multifunctional nanocarriers for the treatment of periodontitis: Immunomodulatory, antimicrobial, and regenerative strategies.

Oral Dis 2018 Dec 19. Epub 2018 Dec 19.

Periodontal Biology Laboratory, Department of Conservative Dentistry, Faculty of Dentistry, Universidad de Chile, Santiago, Chile.

Periodontitis is an inflammatory disease, in which the host immuno-inflammatory response against the dysbiotic subgingival biofilm leads to the breakdown of periodontal tissues. Most of the available treatments seem to be effective in the short-term; nevertheless, permanent periodical controls and patient compliance compromise long-term success. Different strategies have been proposed for the modulation of the host immune response as potential therapeutic tools to take a better care of most susceptible periodontitis patients, such as drug local delivery approaches. Read More

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http://dx.doi.org/10.1111/odi.13023DOI Listing
December 2018
2 Reads

Computer-assisted analysis of immunohistological parameters in oral giant cell granulomas.

Oral Dis 2018 Dec 18. Epub 2018 Dec 18.

Section of Oral and Maxillofacial Pathology, Division of Diagnostic and Surgical Sciences, School of Dentistry, University of California at Los Angeles, Los Angeles, California.

Objective: The aim of this study was to examine the relationship between active osteoclasts, as defined by positive nuclear NFATc1 signals, and the clinical behaviors of oral giant cell granulomas.

Materials And Methods: NFATc1 immunohistochemical and TRAP-Cbfa1 double immunofluorescence stainings were performed on 9 cases of peripheral giant cell granulomas (PGCGs), 9 cases of central giant cell granulomas (CGCGs) with a recurrent history, and 10 cases of CGCGs without a recurrent history. The results were photographed and quantified by ImageJ. Read More

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http://dx.doi.org/10.1111/odi.13022DOI Listing
December 2018

Clinicopathologic study on a rare variant of ameloblastoma with basal cell features.

Oral Dis 2018 Dec 17. Epub 2018 Dec 17.

Shandong Provincial Key Laboratory of Oral Tissue Regeneration, School of Stomatology, Shandong University, Jinan, Shandong Province, China.

Objectives: To investigate the clinical features, pathologic manifestations, and biologic behaviors of a variant of ameloblastoma with basal cell features (AM-BC).

Materials And Methods: Following retrospective review of the clinical and pathological data of six cases of AM-BC, we described their histological and immunohistochemical (IHC) features and discussed the biologic behaviors, prognoses, pathogenesis, and clinical relevance of AM-BC. Direct sequencing of polymerase chain reaction products was also performed in all cases. Read More

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http://dx.doi.org/10.1111/odi.13018DOI Listing
December 2018
2 Reads

Effects of Xerostom products on xerostomia in primary Sjögren's syndrome: A randomized clinical trial.

Oral Dis 2018 Dec 17. Epub 2018 Dec 17.

Department of Dental Clinical Specialties, School of Dentistry, Complutense University, Madrid, Spain.

Objectives: To assess the effects of Xerostom toothpaste and mouthwash in primary Sjögren's syndrome (pSS) patients with xerostomia.

Subjects And Methods: A double-blinded, randomized study where patients were assigned at baseline test or control products. Patients used the products 3 times/day/28 days. Read More

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http://dx.doi.org/10.1111/odi.13019DOI Listing
December 2018
1 Read

Oral microbiomes in children with asthma and dental caries.

Oral Dis 2018 Dec 18. Epub 2018 Dec 18.

Center of Shared Scientific Equipment, Institute for Cellular and Intracellular Symbiosis, Ural Branch of Russian Academy of Sciences, Orenburg, Russia.

Objective: Recently, a significant association between dental caries and the severity of bronchial asthma in children has been revealed. This finding indicates a possible relationship between the oral microbiome and the pathogenesis of asthma. The purpose of our study was to estimate differences in the dental plaque microbiota of asthmatic children with and without dental caries by 16S rDNA sequencing. Read More

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http://dx.doi.org/10.1111/odi.13020DOI Listing
December 2018

Prevalence of temporomandibular disorders and its clinical signs in Chinese students, 1979-2017: a systematic review and meta-analysis.

Oral Dis 2018 Dec 13. Epub 2018 Dec 13.

College of Stomatology, Chongqing Medical University, Chongqing, China.

Objective: This study intends to assess the prevalence of temporomandibular disorders and its clinical signs in Chinese students.

Materials And Methods: Search strategies were performed in 7 electronic databases, and the reference lists from potentially relevant studies were searched manually. Only observational studies that met the eligibility criteria were selected. Read More

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http://dx.doi.org/10.1111/odi.13016DOI Listing
December 2018

Lip cancer: Reconsidering the at-risk patients with pathological assessment.

Oral Dis 2018 Dec 13. Epub 2018 Dec 13.

Department of Pathology, Ankara A.Y. Oncology Education and Research Hospital, Ankara, Turkey.

Objectives: This study was aimed to overview the treatment protocols of lip cancer and find out a cutoff point of tumor diameter and depth of invasion (DOI) for the survival parameters.

Materials And Methods: One hundred and ninety-one patients with lip SCC were studied.

Results: The average age of the patients was 62 years. Read More

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http://dx.doi.org/10.1111/odi.13017DOI Listing
December 2018
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The impact of age on oral squamous cell carcinoma: A longitudinal cohort study of 2,782 patients.

Oral Dis 2018 Dec 12. Epub 2018 Dec 12.

Department of Oral and Maxillofacial-Head and Neck Oncology, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.

Background: The purposes of this study were to assess the influence of age on oral squamous cell carcinoma patients and sought to analyze the reasons that may contribute to this difference.

Methods: This study enrolled 2,782 patients included 2,443 patients in a retrospective cohort to find the influence of age and 339 patients in a prospective cohort to testify these findings. The patients were divided into young age-group (≤40 years old), moderate age-group (41-75 years old), and advanced age-group (>75 years old). Read More

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http://dx.doi.org/10.1111/odi.13015DOI Listing
December 2018
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Radical vs conservative treatment of intraosseous ameloblastoma: Systematic review and meta-analysis.

Oral Dis 2018 Dec 12. Epub 2018 Dec 12.

Department of Oral and Maxillofacial Surgery/Pathology, Amsterdam UMC and Academic Centre for Dentistry Amsterdam (ACTA), Cancer Center Amsterdam, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.

Objectives: The aim of the present study was to assess the outcomes of radical and conservative treatment approaches of solid/multicystic and unicystic ameloblastoma in terms of recurrence rates.

Material And Methods: A systematic review and meta-analysis was conducted based on the PRISMA statement. Search was performed using PubMed, Embase, SCOPUS, and Web of Science for articles published from January 1969 until March 2018. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/odi.13014
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http://dx.doi.org/10.1111/odi.13014DOI Listing
December 2018
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Developmental defects of enamel in the deciduous incisors of infants born preterm: Prospective cohort.

Oral Dis 2019 Mar 1;25(2):543-549. Epub 2019 Jan 1.

Faculty of Dentistry, Universidade Federal de Goiás, Goiânia, GO, Brazil.

Objective: Developmental defects of enamel (DDE) in preterm infants still require clarification and may favour dental caries, lower food intake and greater difficulty with weight-height gain. We evaluated factors associated with DDE in preterm infants.

Subjects And Methods: In this prospective cohort study, we monitored 54 prematurely born infants from birth to 24 months of age. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/odi.13011
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http://dx.doi.org/10.1111/odi.13011DOI Listing
March 2019
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Local injection of RANKL facilitates tooth movement and alveolar bone remodelling.

Oral Dis 2019 Mar 6;25(2):550-560. Epub 2019 Jan 6.

Department of Orthodontics, Institute of Craniofacial Deformity, College of Dentistry, Yonsei University, Seoul, Korea.

Objectives: To investigate the effect of local injection of receptor activator of nuclear factor kappa B ligand (RANKL) on experimental tooth movement and subsequent alveolar bone remodelling in mice.

Materials And Methods: Sixty mice were randomised to receive daily local RANKL or phosphate-buffered saline injections in the buccal premaxillary bone for 14 of 21 days of incisor movement, followed by a 21-day retention period. Five mice from each group were euthanised on days 0, 3, 7, 14, 21 and 42, and specimens were prepared for haematoxylin and eosin, tartrate-resistant acid phosphatase and immunohistochemical staining. Read More

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http://dx.doi.org/10.1111/odi.13013DOI Listing
March 2019
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Evaluation of the serum levels of galectin-3 in patients with oral lichen planus disease.

Oral Dis 2019 Mar 6;25(2):466-470. Epub 2019 Jan 6.

Oral and Dental Disease Research Center, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.

Objectives: Galectin-3, a member of beta-galactoside-binding proteins, can be found in cytoplasm and nucleus as well as extracellularly in various tissues and involved in many physiological and pathological processes. We aimed to measure the serum levels of galectin-3 in oral lichen planus (OLP) disease and compare the result with that observed in healthy ones.

Materials And Methods: In this cross-sectional study, the serum levels of galectin-3 were measured in 56 healthy individuals and 53 pathologically proven OLP patients including those with atrophic/erosive (33 cases) or reticular (20 cases) lesions, using enzyme-linked immunosorbent assay (ELISA). Read More

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http://doi.wiley.com/10.1111/odi.13012
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http://dx.doi.org/10.1111/odi.13012DOI Listing
March 2019
22 Reads
2.427 Impact Factor

NTN1 gene was risk to non-syndromic cleft lip only among Han Chinese population.

Oral Dis 2019 Mar 19;25(2):535-542. Epub 2018 Dec 19.

State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Department of cleft lip and palate, West China Hospital of Stomatology, Sichuan University, Chengdu, China.

Objective: Genome-wide association studies (GWAS) found NTN1, NOG and the region between CREBBP and ADCY9 were risks to non-syndromic cleft lip with or without cleft palate (NSCL/P). However, the association of single nucleotide polymorphisms (SNPs) in these genes with NSCL/P in Western China is unknown.

Subjects And Methods: We selected seven SNPs in NTN1, NOG and between CREBBP and ADCY9, and then performed transmission disequilibrium test (TDT), parent-of-origin effect and sliding window haplotype analysis to test the associations among 302 NSCL/P case-parent trios from Western Han Chinese. Read More

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http://doi.wiley.com/10.1111/odi.13009
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http://dx.doi.org/10.1111/odi.13009DOI Listing
March 2019
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Effect of periodontal treatment on Aggregatibacter actinomycetemcomitans colonization and serum IgG levels against A. actinomycetemcomitans serotypes and Omp29 of aggressive periodontitis patients.

Oral Dis 2019 Mar 27;25(2):569-579. Epub 2018 Dec 27.

Division of Periodontics, Department of Stomatology, School of Dentistry, University of Sao Paulo, Sao Paulo, Brazil.

Objective: To evaluate the effect of the periodontal treatment on Aggregatibacter actinomycetemcomitans JP2 clone, and the IgG serum levels against its outer membrane protein (Omp29) and A. actinomycetemcomitans serotypes in aggressive periodontitis (AgP).

Subjects And Methods: Seventeen patients with generalized (GAgP), 10 with localized (LAgP), and 10 healthy controls were included. Read More

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http://doi.wiley.com/10.1111/odi.13010
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http://dx.doi.org/10.1111/odi.13010DOI Listing
March 2019
3 Reads