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Head Neck Pathol 2019 Mar 29;13(1):4-15. Epub 2019 Jan 29.

The Ohio State University, 305 W. 12 Ave, Columbus, OH, 43210, USA.

Erythematous lesions of the oral mucosa are common and can reflect a variety of conditions, ranging from benign reactive or immunologically-mediated disorders to malignant disease. Together with vascular abnormalities, which can vary from reddish to bluish-purple in color, the differential diagnosis for erythematous oral mucosal change is quite diverse. This review focuses on salient clinical features and histopathologic findings of selected conditions which clinically present as red or vascular-like oral mucosal alterations, including oral vascular malformations and neoplasms, pyogenic granuloma, localized juvenile spongiotic gingival hyperplasia, denture stomatitis, benign migratory glossitis (geographic tongue), orofacial granulomatosis, granulomatosis with polyangiitis (Wegener granulomatosis), megaloblastic anemia, and erythroplakia. Read More

Head Neck Pathol 2019 Mar 29;13(1):103-113. Epub 2019 Jan 29.

Academic Unit of Oral and Maxillofacial Medicine and Pathology, School of Clinical Dentistry, University of Sheffield, Claremont Crescent, Sheffield, S10 2TA, UK.

Lesions of the gingivae are amongst the commonest lesions seen in patients and the vast majority are reactive hyperplasias, related to a number of chronic irritant stimuli. However, there are a number of entities that have a predilection for the gingivae, which are much less common in other parts of the oral cavity. The purpose of this paper is to discuss the clinical and histological differential diagnoses when presented with a lump on the gingivae, including the approach to diagnosis and diagnostic pitfalls. Read More

J Oral Pathol Med 2019 Jan 23. Epub 2019 Jan 23.

Brazilian Centre for Evidence-Based Research, Federal University of Santa Catarina (UFSC), Florianópolis, Santa Catarina, Brazil.

Objective: To assess the prevalence of oral mucosal disorders during pregnancy.

Methods: Observational studies were selected by two reviewers in a two-phase process. Search strategies were applied at CINAHL, LILACS, LIVIVO, PubMed, Scopus, Web of Science, Google Scholar, OpenGrey, and ProQuest. Read More

In Vivo 2019 Jan-Feb;33(1):251-254

Department of Pathology, Immunology and Laboratory of Medicine, University of Florida College of Medicine, Gainesville, FL, U.S.A.

Pyogenic granuloma (PG) represents a lobular capillary proliferation commonly seen in the skin or oral mucosa. They are rarely reported in the gastrointestinal tract. The mechanism underlying PG pathogenesis is not well understood. Read More

J Am Dent Assoc 2019 Feb 7;150(2):147-153.e2. Epub 2018 Dec 7.

Background: Localized juvenile spongiotic gingival hyperplasia (LJSGH) is a gingival lesion of unknown cause. The purpose of this study is to present a series of LJSGH cases and compare the findings with the literature.

Methods: After obtaining institutional review board approval, cases of biopsy-proven LJSGH from 2008 through 2018 were retrieved from the University of Pittsburgh Oral Pathology Biopsy Service archives and reviewed. Read More

J Exp Ther Oncol 2018 Nov;12(4):291-294

MBBS student, Hind Institute of Medical Sciences, Lucknow, U.P, India.

Objective: A telangiectatic granuloma is a localized reactive lesion associated with prolonged irritation to the soft tissues. It may be misdiagnosed as a vascular malformation, hemangiomas, angiosarcomas, etc; as clinical presentation of the lesions resembles each other. Here, we present a case of asymptomatic swelling in the maxilla of a 17-year old female patient. Read More

J Am Acad Dermatol 2018 Nov 14. Epub 2018 Nov 14.

Department of Dermatology, Boston University School of Medicine, Boston, MA. Electronic address:

A diverse spectrum of benign oral mucosal lesions exists, presenting as either isolated oral findings or in association with dermatological conditions. Oral lesions can closely resemble one another; therefore, it is important for clinicians to be able to recognize their distinctive features and recognize benign versus malignant disease and when a biopsy is warranted. In this continuing medical education series, we review oral anatomy and the clinical attributes of several benign lesions of the oral cavity along with the appropriate management and therapeutic modalities. Read More

Indian J Dent Res 2018 Sep-Oct;29(5):678-682

Department of Periodontology, Government Dental College and Hospital, Mumbai, Maharashtra, India.

The peripheral giant cell granuloma (PGCG) is a benign oral lesion occurring on the gingiva and alveolar ridge. It is the most common oral lesion and occurs at an average age of 30 years. The upsurge in the levels of estrogen and progesterone in pregnancy leads to a plethora of changes in various parts of human body, including the oral cavity. Read More

Case Rep Dent 2018 14;2018:5180385. Epub 2018 Oct 14.

School of Dentistry, University Center of Patos de Minas (UNIPAM), Patos de Minas, MG, Brazil.

Oral surgery to remove pyogenic granuloma in a high-risk patient is reported. A 47-year-old man with gastroesophageal reflux disease, diabetes mellitus II, dyslipidemia, and chronic coronary insufficiency (myocardial infarction within 2 years) with episodes of unstable angina was submitted to an excisional biopsy of hemorrhagic lesion in the lingual right mandibular gingiva. During dental treatment, the arterial blood pressure, oxygen saturation, heart rate, and electrocardiogram were monitored. Read More

Am J Clin Dermatol 2018 Nov;19(Suppl 1):31-39

Institut Universitaire du Cancer Toulouse - Oncopole, 1 avenue Irène Joliot-Curie, 31059, TOULOUSE Cedex 9, France.

Targeted therapies and immunotherapies are associated with a wide range of dermatologic adverse events (dAEs) resulting from common signaling pathways involved in malignant behavior and normal homeostatic functions of the epidermis and dermis. Dermatologic toxicities include damage to the skin, oral mucosa, hair, and nails. Acneiform rash is the most common dAE, observed in 25-85% of patients treated by epidermal growth factor receptor and mitogen-activated protein kinase kinase inhibitors. Read More

Pediatr Dermatol 2019 Jan 15;36(1):e41-e43. Epub 2018 Oct 15.

Dermatopathology Division, Department of Pathology and Laboratory Medicine, Sylvester Comprehensive Cancer Center and Miller School of Medicine, University of Miami, Miami, Florida, USA.

Disseminated congenital pyogenic granuloma (DCPG) is an uncommon condition. Individual lesions of DCPG share clinical and histologic similarities with infantile hemangioma (IH); endothelial glucose transporter 1 (GLUT-1), which is highly expressed in IH but generally not in pyogenic granulomas (PG), is an important diagnostic tool. Treatment for DCPG remains difficult. Read More

Open Dent J 2018 29;12:560-566. Epub 2018 Aug 29.

Department of Operative Dentistry, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.

Introduction: The isolation of stem cells from pathologically damaged dental tissues has been examined only by a few studies. The purpose of this study was to evaluate the possibility of isolation of stem cells from pyogenic granuloma.

Methods: Pyogenic granuloma tissues were enzymatically digested and the resulting single cells were cultured. Read More

Orv Hetil 2018 Sep;159(37):1516-1524

Fogorvostudományi Kar, Szájsebészeti Tanszék, Szegedi Tudományegyetem Szeged.

Introduction: In a clinicopathological retrospective epidemiological study we investigated benign tumors and tumor-like lesions located in the orofacial region, diagnosed at the Universiy of Szeged, Department of Oral Medicine.

Method: During a 54-year period (1960-2014), 14 661 biopsies were taken. The included subjects were 7491 patients diagnosed with benign tumors and tumor-like lesions. Read More

Case Rep Dent 2018 12;2018:2474706. Epub 2018 Aug 12.

Department of Oral and Maxillofacial Sciences, "Sapienza" University of Rome, Rome, Italy.

The aim is to discuss four cases of gingival reactive hyperplastic lesions in patients with a history of excision of oral neoplastic lesions and rehabilitation by a free revascularized flap of the iliac crest. One female and 3 male patients were referred due to the presence of exophytic lesions at the rehabilitated sites. The clinical examination revealed that the poor oral hygiene was the common trigger factor in all the cases, in addition to trauma from the upper left second molar in the first case, pericoronitis related to a partially erupted lower right third molar in the third case, and poor stability of an upper removable partial denture in the fourth case. Read More

Dent Med Probl 2018 Jan-Mar;55(1):83-86

Department of Periodontology, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Mangalore, India.

Most of the reactive lesions in the oral cavity arise from gingiva. Fibroma, focal fibrous hyperplasia, pyogenic granuloma, and peripheral ossifying fibroma are the commonly encountered lesions of gingiva. Peripheral ossifying fibroma (POF) frequently arises from the peripheral tissues like gingiva. Read More

J Indian Soc Periodontol 2018 Jul-Aug;22(4):360-364

Department of Periodontology, The Oxford Dental College, Bengaluru, Karnataka, India.

Pyogenic granuloma (PG) is an inflammatory hyperplastic lesion of the oral cavity. The most common etiological factors for PG are low-grade local irritation, traumatic injury, or hormonal factors. Clinically, it appears to be smooth or lobulated exophytic lesion. Read More

BMJ Case Rep 2018 Aug 9;2018. Epub 2018 Aug 9.

Department of Conservative Dentistry and Endodontics, King George's Medical University, Lucknow, Uttar Pradesh, India.

Pyogenic granuloma is a 'reactive lesion' in the oral cavity caused due to hormonal imbalance or poor oral hygiene. There are different methods to excise this lesion but most successful is treatment with lasers. Currently, there are different lasers available commercially and are used by clinicians to excise this lesion. Read More

J Craniofac Surg 2018 Nov;29(8):2160-2163

Department of Biomedical, Odontostomatological, Sciences and Morphological and Functional Images, School of Dentistry, University of Messina, Messina.

The use of laser in oral surgery and periodontology is a matter of debate, mainly because of the lack of consensual therapeutic protocols. The aim of this study was to evaluate the surgical advantages of diode laser versus traditional surgery with a cold blade for the surgical excision of pyogenic granuloma (PG). Twenty-one patients (10 males, 11 females, aged 19-66 years; mean age: 46. Read More

J Korean Assoc Oral Maxillofac Surg 2018 Jun 26;44(3):136-139. Epub 2018 Jun 26.

Department of Oral Medicine and Pathology, Periodontology and Implant Biology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece.

This study presents a case of an oral angioleiomyoma along with its clinical diagnostic approach and laboratory confirmation. The differential diagnosis, especially from angioleiomyosarcoma, is also included. A 51-year-old patient presented with a tumor-like lesion on his upper labial mucosa. Read More

J Indian Soc Periodontol 2018 May-Jun;22(3):273-276

Department of Oral and Maxillofacial Pathology and Oral Microbiology, Surendera Dental College and Research Institute, Sri Ganganagar, Rajasthan, India.

Exophytic gingival lesions are more frequently encountered intraorally, out of which few are reactive in nature. Pyogenic granuloma (PG) is one of the commonly occurring reactive benign mucocutaneous lesions; exact etiopathogenesis remains unclear. Although surgical excision is the treatment of choice, sometimes it may induce residual soft defect formation which further creates an esthetic problem, root sensitivity, etc. Read More

Int Wound J 2018 Dec 29;15(6):909-913. Epub 2018 Jun 29.

Department of Dermatology and Immunodermatology, Medical University of Warsaw, Warsaw, Poland.

Mucous membrane pemphigoid (MMP) is a group of chronic autoimmune sub-epithelial blistering disorders, which mostly affect the oral mucosa and the conjunctiva. MMP is very diverse in terms of both the clinical and immunological features (IgG and IgA autoantibodies may react with different antigens). MMP can be induced by infections and medication, including ophthalmologic medication, which may lead to the development of eye lesions. Read More

J Coll Physicians Surg Pak 2018 Jul;28(7):575

Department of Oral and Maxillofacial Pathology, King George's Medical University (KGMU), Lucknow, Uttar Pradesh, India.

J Clin Exp Dent 2018 Jun 1;10(6):e561-e566. Epub 2018 Jun 1.

BDS, MBA, PhD, Assistant Professor, Oral Diagnostic Sciences Department, King Abdulaziz University, Faculty of Dentistry, Jeddah, Saudi Arabia.

Background: The gingiva is part of the periodontium supporting structures surrounding the teeth and commonly involved in gingival and periodontal conditions. Assessing the distribution of gingival lesions is important for evaluating the prevalence of periodontal disease in the population to optimize the oral health care services. The purpose of this study is to report the frequency and distribution of gingival lesions biopsied from 1996-2016. Read More

J Periodontol 2018 Jun;89 Suppl 1:S74-S84

Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences, Japan.

Periodontal health is defined by absence of clinically detectable inflammation. There is a biological level of immune surveillance that is consistent with clinical gingival health and homeostasis. Clinical gingival health may be found in a periodontium that is intact, i. Read More

J Clin Periodontol 2018 Jun;45 Suppl 20:S68-S77

Division of Periodontology, Niigata University Graduate School of Medical and Dental Sciences, Japan.

Periodontal health is defined by absence of clinically detectable inflammation. There is a biological level of immune surveillance that is consistent with clinical gingival health and homeostasis. Clinical gingival health may be found in a periodontium that is intact, i. Read More

Biotech Histochem 2018 21;93(5):336-339. Epub 2018 May 21.

a Department of Oral and Maxillofacial Pathology , St. Joseph Dental College , Eluru 534004 , Andhra Pradesh , India.

Toto bodies are eosinophilic structures that resemble the cells of the superficial cell layer of the oral epithelium. Toto bodies commonly are associated with inflammatory gingival and other mucosal lesions including pyogenic granuloma, irritational fibroma, epulis fissuratum, peripheral giant cell granuloma and inflammatory hyperplastic gingivitis. We evaluated staining characteristics of Toto bodies to establish their origin and to identify their significance in lesions. Read More

J Indian Soc Periodontol 2018 Mar-Apr;22(2):174-177

Department of Periodontics and Oral Implantology, Institute of Dental Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India.

Pyogenic granuloma (PG) is a reactive hyperplasia of connective tissue that occurs in response to low-grade local irritation, traumatic injury, foreign materials, or hormonal causes and rarely associated with bone loss. Although solitary PG is a common lesion in the orofacial region, presence of multiple such lesions at the same time with associated bone loss is rare. In addition, repeated recurrences of such lesions sometimes frustrate the clinician. Read More

J Clin Pediatr Dent 2018;42(5):383-385. Epub 2018 May 15.

Pyogenic granuloma, also called lobular capillary hemangioma, is a benign vascular lesion of the skin and mucous membranes. While the majority of pyogenic granulomas in the oral cavity involve the gingiva, they also infrequently present at other sites including lips, oral mucosa, palate, and tongue. We report a case of a pyogenic granuloma of the tongue in a five-year old female patient. Read More

J Investig Clin Dent 2018 Nov 11;9(4):e12342. Epub 2018 May 11.

Department of Diagnostic Sciences and Oral Medicine, University of Tennessee Health Science Center, College of Dentistry, Memphis, TN, USA.

Reactive lesion formation around dental implants a complication that has been given much consideration. These lesions can lead to marginal bone loss, and consequently, implant failure. In the present systematic review, all reported reactive lesions associated with dental implants in the literature were assessed. Read More

Melanoma Res 2018 08;28(4):363-367

Department of Dermatology, Laser Unit, Rabin Medical Center.

Amelanotic melanomas (AMMs) account for a small proportion of all melanomas. They pose a risk of delayed diagnosis and, consequently, poor prognosis. AMMs may atypically present as a pyogenic granuloma-like lesion. Read More

Int J Surg Pathol 2018 Dec 8;26(8):735-738. Epub 2018 May 8.

1 Department of Pathology and Laboratories, Fundación Santa Fe de Bogotá, Bogotá DC, Colombia.

Pyogenic granuloma (PG) is a capillary hemangioma mainly found in the skin and oral mucosa, but rarely described in the esophagus. We report the case of a 66-year-old man who consulted for retrosternal pain. Endoscopic studies showed a 28-mm polypoid mass located at the distal esophageal mucosa. Read More

J Oral Maxillofac Pathol 2018 Jan-Apr;22(1):147

Department of Oral and Maxillofacial Pathology, Dental and Periodontal Research Centre, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.

Background: Many studies have reported that macrophages and eosinophils are involved in the pathogenesis of several diseases. To the best of our knowledge, this is the first study comparing macrophages and eosinophils in oral reactive lesions.

Aims: In this study, we aimed to determine the contribution of macrophages and eosinophils to the pathogenesis of oral reactive lesions and the relationships between these biomarkers and the diverse histopathologic features. Read More

Braz J Otorhinolaryngol 2018 Apr 17. Epub 2018 Apr 17.

Department of Pathology, Federal University of Santa Catarina, Florianópolis, SC, Brazil.

Introduction: Reactive hyperplastic lesions develop in response to a chronic injury simulating an exuberant tissue repair response. They represent some of the most common oral lesions including inflammatory fibrous hyperplasia, oral pyogenic granuloma, giant cell fibroma, peripheral ossifying fibroma, and peripheral giant cell lesions.

Objective: The incidence of those lesions was investigated in an oral pathology service, and the clinical characteristics, associated etiological factors, concordance between the clinical and histopathological diagnostic was determined. Read More

Clin Imaging 2018 Jul - Aug;50:246-249. Epub 2018 Apr 13.

Stanford University School of Medicine, 300 Pasteur Drive, Room S-047, Stanford, CA 94305, United States.

Lobular capillary hemangiomas are acquired benign vascular neoplasms which typically affect the skin and mucous membranes. While these lesions commonly involve the head and neck, particularly the oral cavity, there are no reports in the literature of lobular capillary hemangioma arising from the mandible. The diagnosis of such a rare entity can therefore be challenging, especially as it may mimic more aggressive lesions, including malignancy. Read More

Plast Reconstr Surg 2018 05;141(5):709e-717e

Boston, Mass. From the Department of Plastic and Oral Surgery, Children's Hospital Boston, Harvard Medical School.

Background: Vascular anomalies currently are classified according to their clinical and histological characteristics. Recent advances in molecular genetics have enabled the identification of somatic mutations in most types of vascular anomalies. The purpose of this study was to collate information regarding the genetic basis of vascular anomalies. Read More

Med Oral Patol Oral Cir Bucal 2018 May 1;23(3):e320-e325. Epub 2018 May 1.

41 Amyclon Str, 11142 Lamprini, Athens, Greece,

Background: To describe the incidence, demographic and clinical features of 1187 localized gingival enlargements.

Material And Methods: 1187 cases of localized gingival enlargements diagnosed during a 20-year period were retrospectively collected. The patients' gender and age, as well as the main clinical features of the tumors were retrieved from the biopsy report forms. Read More

Clin Case Rep 2018 04 27;6(4):690-693. Epub 2018 Feb 27.

Department of Pathology Chitwan Medical College Teaching Hospital P.O. Box 42, Bharatpur 10 Chitwan Nepal.

Pyogenic granuloma is a benign vascular neoplasm of the oral cavity that usually presents as a small nodular lesion, the gingiva being the commonest site. Occasionally it occurs at uncommon sites with unusual sizes. Here we describe two cases of oral pyogenic granulomas that had an unusual presentation. Read More

Dermatol Online J 2018 Feb 15;24(2). Epub 2018 Feb 15.

Department of Biosciences and Oral Diagnosis, Institute of Science and Technology, São Paulo State University (Unesp); São José dos Campos, SP, Brazil.

Intravascular papillary endothelial hyperplasia (IPEH) is an unusual benign, non-neoplastic vascular lesion that usually occurs in skin, but is uncommon in the oral cavity. Herein, we review the pertinent literature of oraiiPEH and report a new mixed form. A 61-year- old man presented with an ulcerated nodule in the lingual portion of the gingiva related to the left mandibular canine. Read More

Medicine (Baltimore) 2018 Mar;97(13):e9934

Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo.

Rationale: Oral metastases occur more commonly in bone, but can also manifest in soft tissues and eventually resemble a reactive lesion. Few cases of oral metastases mimicking reactive lesions in soft tissues have been reported to date.

Patient Concerns: We report a metastasis of gastric carcinoma (GC) to the oral mucosa without bone involvement in a 43 yom clinically and microscopically mimicking a reactive lesion. Read More

J Oral Maxillofac Pathol 2018 Jan;22(Suppl 1):S102-S107

Division of Oral and Maxillofacial Pathology, Columbia University Medical Center, New York, USA.

Tumor metastasis to the oral cavity is rare and is usually an indication of late-stage disease and poor prognosis. While, there are reports of renal cell carcinoma (RCC) metastatic to oral cavity, vast majority of them are to the jaw. Herein, we present a case of a 78-year-old woman with RCC metastasis limited to the oral soft tissue without any bone involvement. Read More

J Indian Soc Periodontol 2017 Jul-Aug;21(4):258-263

Department of Oral and Maxillofacial Pathology and Microbiology, SDM College of Dental Sciences and Hospital, Dharwad, Karnataka, India.

Objective: This study reviews, analyzes, and compares the demographic data, histopathological features and discusses the treatment and prognosis of reactive lesions (RLs).

Materials And Methods: Retrospective study was performed on the departmental archives from July 2006 to July 2016 (total 5000 cases) comprising of 659 cases of RLs of the oral cavity. The recorded data included age, gender, size, site, duration, habits, etiology, histopathological diagnosis, treatment, and prognosis. Read More

Indian J Dent Res 2018 Jan-Feb;29(1):61-66

Department of Community Dentistry, MIDSR Dental College, Latur, India.

Context: The reactive lesions are relatively common in the oral cavity because of the frequency with which the tissues are injured. They often result from a known stimulus or injury such as dental plaque, calculus, or foreign material.

Aims: : The aim of this study was to review the clinicopathologic features of reactive hyperplastic lesions (RHLs) of the oral cavity at MIDSR, Dental College and Hospital, Latur, Maharashtra, and to compare these data with those of previously reported studies. Read More

J Indian Soc Periodontol 2017 May-Jun;21(3):241-244

Department of Periodontology, Dayananda Sagar College of Dental Sciences, Bengaluru, Karnataka, India.

Pyogenic granuloma (PG) is a nonneoplastic, tumor-like growth commonly seen in the oral mucosa or skin. Although nonpathological, its existence might lead to complications such as secondary infections or diastema formation. Hence, surgical removal of the growth seems mandatory. Read More

J Oral Maxillofac Pathol 2017 Sep-Dec;21(3):415-420

Department of Oral Pathology and Microbiology, Government Dental College, Kottayam, Kerala, India.

Hemangioendothelioma commonly occurs in the superficial or deep soft tissue of the extremities, lungs, liver, bone and lymph nodes, with oral cavity being a rare location. It is usually benign but can show variable grades of malignancy. According to the histological presentation, hemangioendothelioma has been classified as epithelioid, Kaposiform, hobnail (Dabska-Retiform), epithelioid sarcoma like and composite. Read More

J Oral Maxillofac Pathol 2017 Sep-Dec;21(3):382-386

Department of Periodontics, Post Graduate Institute of Dental Sciences, Pt. B.D. Sharma University of Health Sciences, Rohtak, Haryana, India.

Background And Objective: Reactive proliferations of oral cavity comprise pyogenic granuloma (PG), fibrous hyperplasia (FH), peripheral ossifying fibroma (POF), and peripheral giant-cell granuloma (PGCG). They often pose diagnostic challenges due to their overlapping clinical and histopathological features. This study was conducted to determine the frequency and clinicopathological correlation of reactive hyperplastic lesions in the oral cavity reported in our institute and compared it with other previous studies. Read More

JNMA J Nepal Med Assoc 2017 Jul-Sep;56(207):362-6

Department of Oral and Maxillofacial Pathology, Kantipur Dental College and Teaching Hospital, Kathmandu, Nepal.

Introduction: Oral mucosa can be affected by a variety of soft tissue lesions and conditions. Benign as well as malignant lesions of oral cavity are common. Squamous cell carcinoma is one of the commonest malignancies. Read More

Otolaryngol Clin North Am 2018 Feb;51(1):89-97

Department of Plastic and Oral Surgery, Vascular Anomalies Center, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue Boston, MA, 02115, USA. Electronic address:

Vascular tumors are benign neoplasms, which result from proliferating endothelial cells. These lesions present during infancy or childhood, may affect any location, and exhibit postnatal growth. Local complications include bleeding, tissue destruction, and pain whereas systemic sequelae include thrombocytopenia, congestive heart failure, and death. Read More

Med Oral Patol Oral Cir Bucal 2017 Nov 1;22(6):e686-e693. Epub 2017 Nov 1.

Department of Surgical Sciences, University of Turin, CIR - Dental School, Oral Medicine Section, Via Nizza 230, 10126 Turin, Italy,

Background: The diagnosis and treatment of a variety of non-plaque related gingival diseases have become an integrated aspect of everyday dentistry. The aim of this study was to analyse the relationship between clinical appearance and histopathological features of gingival lesions in a large Northern Italian population.

Material And Methods: A retrospective study of 788 cases of gingival and alveolar mucosal biopsies was set up. Read More

J Craniofac Surg 2018 Jan;29(1):e49-e50

School of Medicine, University of Seville, Virgen del Rocio University Hospital, Seville, Spain.

Pregnancy pyogenic granuloma is considered a benign common growth that usually develops on the gingiva in the second and third trimester of gestation, in response to local irritation, trauma or hormonal factors. Here, the authors report a case of a primigravida who presented an extragingival pyogenic granuloma with a rapid progression in the post-partum. The occurrence on the lower lip in the first few days after delivery was a relatively rarity in the present case which provoked a meaningful state of anxiety and cancerophobia to the female. Read More

Dtsch Arztebl Int 2017 Sep;114(39):659