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Dermatol Ther 2022 Jun 21:e15654. Epub 2022 Jun 21.

Department of Oral and Maxillofacial Surgery, School and Hospital of Stomatology, Cheeloo College of Medicine, Shandong University & Shandong Key Laboratory of Oral Tissue Regeneration & Shandong Engineering Laboratory for Dental Materials and Oral Tissue Regeneration, Shandong, RP, China.

J Imaging 2022 May 22;8(5). Epub 2022 May 22.

Clinic of Cranio-Maxillofacial and Oral Surgery, Center of Dental Medicine, University of Zurich, 8032 Zurich, Switzerland.

Soft-tissue lesions in the oral cavity, one of the most common sites for tumors and tumor-like lesions, can be challenging to diagnose and treat due to the wide spectrum from benign indolent to invasive malignant lesions. We report an abnormally large, rapidly growing hyperplastic lesion originating from the buccal mucosa in a 28-year-old male patient. Clinical examination revealed a well-circumscribed, smooth-surfaced, pinkish nodular lesion measuring 2. Read More

BMC Oral Health 2022 04 29;22(1):154. Epub 2022 Apr 29.

Department of Oral and Maxillofacial Pathology, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Up to now, limited research has been done on a significant number of cases with all types of gingival lesion. Besides, the available literature does not provide reliable data on the epidemiology of gingival lesions, especially non-reactive lesions. Thus, the present study aimed to analyze the frequency and distribution of gingival lesions in an Iranian population. Read More

Gen Dent 2022 May-Jun;70(3):56-59

The use of high-power diode laser technology follows the principles of minimally invasive dentistry. Laser technology is used frequently in pediatric dentistry, especially in surgical procedures, because this approach favors hemostasis, eliminates the use of sutures, improves healing, minimizes treatment time, reduces the sensation of pressure and vibration experienced by the patient, and creates more comfortable postoperative conditions. This article describes the use of high-power diode lasers to perform 3 minor oral surgical procedures--biopsy, lingual frenectomy, and operculectomy--in 2 children. Read More

J Oral Maxillofac Pathol 2022 Feb 28;26(Suppl 1):S119-S123. Epub 2022 Feb 28.

Department of Maxillofacial Surgery and Diagnostic Science, College Dentistry, King Saud Bin Abdulaziz University for Health Science, King Abdullah International Medical Research Center, King Saud University, Riyadh, Saudi Arabia.

Pyogenic granuloma (PG) is a benign nonneoplastic mucocutaneous lesion. It occurs as a result of chronic irritation or due to hormonal changes. The most favorable site for this fairly common lesion is gingiva, but rarely, it can occur outside the oral cavity, later often difficult to diagnose, as a diverse group of the pathologic process can produce such lesions outside the oral cavity. Read More

Case Rep Pathol 2022 29;2022:5641608. Epub 2022 Mar 29.

Department of Pathology, Gospel Hospital, Kosin University, 262 Gamcheon-ro, Seo-gu, Busan, Republic of Korea 49267.

Background: Lobular capillary hemangiomas typically present as skin or oral mucosa lesions and have rarely been described in unusual sites, including the gastrointestinal tract. Most colonic lobular capillary hemangiomas, either asymptomatic or associated with GI bleeding, have been amenable to endoscopic treatment in literatures. . Read More

Cureus 2022 Feb 24;14(2):e22572. Epub 2022 Feb 24.

Oral Medicine, University of Pennsylvania School of Dental Medicine, Philadelphia, USA.

Pyogenic granuloma (PG) is an oral reactive inflammatory hyperplasia of connective tissue that can occur in response to hormonal changes and local irritation such as calculus, fractured teeth, rough dental restorations, and foreign materials. It is nonneoplastic and predominant in the second decade of life in young adult females. The most common site of involvement is the gingiva. Read More

Cureus 2022 Feb 2;14(2):e21849. Epub 2022 Feb 2.

Dermatology, King Saud Bin Abdulaziz University for Health Sciences College of Medicine, Jeddah, SAU.

Pyogenic granuloma (PG) is a vascular tumor originating from the skin and mucosal membranes. The most common sites include the oral and nasal cavities. It appears as a solitary erythematous lesion that bleeds easily. Read More

J Oral Maxillofac Pathol 2021 Sep-Dec;25(3):550-551. Epub 2022 Jan 11.

Department of Oral Pathology and Microbiology, Sri Aurobindo College of Dentistry, Indore, Madhya Pradesh, India.

Background: Mast cells (MCs) are immune cells derived from a multipotent CD34 precursor. The most significant identifying feature of MCs is the presence of metachromatic granules. MCs are increased in oral reactive lesions and are possibly involved in pathogenesis of these lesions. Read More

Quintessence Int 2022 Apr;53(5):432-435

A 31-year-old man presented with gingival mass-like lesions. The patient reported occasional bleeding from lesions; otherwise, the lesions were asymptomatic. Intraoral examination revealed multiple interdental red/purple soft, sessile, nodular lesions involving both the maxillary and mandibular buccal and lingual gingivae, with poor oral hygiene. Read More

Gen Dent 2022 Mar-Apr;70(2):33-36

Oral lesions may be the initial or only manifestation of leukemia and can be the key to early diagnosis. The varied nature of presenting signs and dentists' general lack of familiarity with oral presentations makes diagnosis challenging. This retrospective review reports a series of cases of leukemia to familiarize dentists with the oral manifestations and facilitate earlier diagnosis or recognition of relapse of this life-threatening disease. Read More

Children (Basel) 2022 Jan 26;9(2). Epub 2022 Jan 26.

Oral and Maxillofacial Pathology, Oral Diagnosis Department, College of Dentistry, University of Sulaimani, Sulaimani 46001, Iraq.

Oral and maxillofacial lesions (OMFLs) in pediatrics differ markedly from their adult counterparts in terms of clinical conduct, pathological behavior, and management. This study aims to determine the frequency of OMFLs among pediatric and adolescent patients and to correlate the demographics information to the site, and histopathological findings. Pathological records of pediatric and adolescent patients were retrieved from three major pathological centers in Sulaimani city of Iraq. Read More

BMC Oral Health 2022 01 7;22(1). Epub 2022 Jan 7.

Pediatric Dentistry and Dental Public Health Department, Faculty of Dentistry, Cairo University, Giza, Egypt.

Objectives: The goal of the current study was to evaluate the relative frequency of oral and maxillofacial pathological lesions among Egyptian children.

Materials And Methods: Records of biopsies submitted to the department of oral and maxillofacial pathology from the year 1999 to 2019 were retrieved and reassessed for all cases under the age of 18 years. Information on age, sex, location of the lesion, and the histopathologic diagnosis was analyzed. Read More

J Clin Pediatr Dent 2021 Dec;45(6):385-388

Natal teeth are infrequent at birth. Dental extraction is the most recommended treatment to avoid complications. Reactive soft tissue lesions associated to natal tooth or its incomplete removal are rare. Read More

SAGE Open Med Case Rep 2021 22;9:2050313X211066411. Epub 2021 Dec 22.

Department of Otorhinolaryngology, University of Malaya, Kuala Lumpur, Malaysia.

Kaposi's sarcoma is the most common AIDS-associated malignancy. Kaposi's sarcoma in the oral cavity and oropharynx present as a macular, papular, or nodular lesion on the palate, gingiva, or tongue which may look pink, reddish, or purplish. Kaposi's sarcoma of the tonsils is relatively less common compared with other sites in the oral cavity and oropharynx. Read More

Int J Clin Pediatr Dent 2021 Sep-Oct;14(5):730-733

Department of Conservative Dentistry and Endodontics, Indira Gandhi Institute of Dental Sciences, Puducherry, India.

Pyogenic granuloma is one of the benign vascular neoplasms seen in the first and second decade of life, with a female predilection. Pyogenic granuloma presents as a small reddish exophytic lesion, gingiva being the commonest site. This report presents a case of recurrent episodes of pyogenic granuloma at a different site at different time intervals in an 8-year-old girl child which was found to be an unusual presentation, and it highlights the importance of early diagnosis and management of the pyogenic granuloma to avoid the discomfort. Read More

Vet Clin North Am Small Anim Pract 2022 Jan;52(1):159-184

Unité de dentisterie et chirurgie oromaxillofaciale, ADVETIA Centre Hospitalier Vétérinaire, 9 avenue Louis Breguet, Vélizy-Villacoublay 78140, France.

Severe oral inflammatory disease is not uncommon in the mouths of canine and feline patients. An approach to oral diagnosis is offered. This article discusses a brief review of important points in the oral diagnosis and management of main canine (canine chronic ulcerative stomatitis (CCUS), eosinophilic stomatitis, and Wegener's granulomatosis (WG)) and feline diseases (feline gingivostomatitis/caudal stomatitis, oral eosinophilic lesions, pyogenic granuloma, and autoimmune diseases with oral manifestations), and-whereby possible-information about the current understanding of disease pathogenesis and treatment is offered. Read More

Medicina (Kaunas) 2021 Oct 7;57(10). Epub 2021 Oct 7.

Department of Oral Pathology, Oral Medicine and Maxillofacial Radiology Goldschleger School of Dental Medicine, Tel-Aviv University, Tel Aviv 39040, Israel.

: Peri-implantitis is a common finding among patients with dental implants. There is no consensus regarding the treatment of this disease, but in many cases, surgical treatment is common practice. A histopathological analysis is not an integral part of suggested protocols. Read More

J Clin Exp Dent 2021 Oct 1;13(10):e1049-e1052. Epub 2021 Oct 1.

DDS, MS, PhD, EBOS. Professor of Oral Surgery, Professor of the Master of Oral Surgery and Implantology. School of Medicine and Health Sciences, University of Barcelona. Researcher at the IDIBELL Institute. Barcelona, Spain.

Peripheral giant cell granuloma (PGCG) is a reactive exophytic lesion classified as a benign tumor of the oral mucosa. Although its etiology is not clear, it may be a consequence of local chronic irritation or persistent trauma. The objective of this case report was to document the main clinical and histopathological characteristics of a patient with a PGCG associated with a dental implant. Read More

Int J Surg Case Rep 2021 Nov 16;88:106513. Epub 2021 Oct 16.

Department of Surgical Oncology, National Institute of Cancer in Cairo, Egypt.

Introduction And Importance: Xeroderma pigmentosum is an autosomal recessive genetic disorder with impaired ability to repair DNA damage. Detection of the intraoral benign and malignant lesion in Xeroderma pigmentosum is uncommon, and the reported few cases were in the lip and tip of the tongue which are related to ultraviolet light exposure.

Case Presentation: We present a case of 20 years old male with erythematous to violet, painless and shiny papule at the right side of the tongue. Read More

J Pharm Bioallied Sci 2021 Jun 5;13(Suppl 1):S116-S119. Epub 2021 Jun 5.

Department of Dentistry, Patna Medical College, Patna, Bihar, India.

Background: The clinical manifestations of these lesions comprises pain, paresthesia, swelling, drainage, tooth loss, root resorption, and facial deformity. Alteration in oral and maxillofacial (OMF) tissues of the lesions may cause esthetically and functionally unfavourable effects in patients.

Aims And Objectives: To determine the frequency of odontogenic cysts, tumors, and other lesions. Read More

J Maxillofac Oral Surg 2021 Sep 7;20(3):439-442. Epub 2020 Apr 7.

Department of Conservative Dentistry and Endodontics, Faculty of Medical Sciences and Research, Karpagam College, Coimbatore, India.

The soft tissues of the oral cavity are constantly subjected to microtrauma due to various factors. The gingiva in particular reacts to these beyond a point resulting in reactive hyperplastic lesions. Amongst these, the pyogenic granuloma and the peripheral ossifying fibroma are the most common clinical entities. Read More

Oral Maxillofac Surg 2022 Jun 17;26(2):333-337. Epub 2021 Aug 17.

Oral Pathology, Department of Stomatology, Public Oral Health, and Forensic Dentistry, Ribeirão Preto Dental School (FORP/USP), University of São Paulo, Ribeirão Preto, SP, 14040-904, Brazil.

The localized juvenile spongiotic gingival hyperplasia (LJSGH) mainly affects the maxillary vestibular attached gingiva of juvenile patients, without sex predilection. Similar lesions involving extragingival sites have not been reported to date. Here, we report 2 cases of extragingival soft tissue lesions with similar clinicopathological features to those reported in LJSGH and 12 cases of intraoral reactive soft tissue lesions microscopically showing LJSGH-like focal areas. Read More

Dermatol Online J 2021 Jul 15;27(7). Epub 2021 Jul 15.

Cedars Dermatology, Cedars-Sinai Medical Group, Los Angeles, CA.

Periungual pyogenic granulomas are benign vascular tumors that present as painful, round, spontaneously bleeding lesions composed of rapidly proliferating capillaries and excess tissue. The vast majority of pyogenic granulomas are caused by physical trauma or infectious agents and they may resolve spontaneously. Herein, we highlight a very rare case of periungual pyogenic granulomas induced by the regularly prescribed oral retinoid acitretin during treatment for congenital palmoplantar keratoderma. Read More

J Oral Maxillofac Pathol 2021 Jan-Apr;25(1):203. Epub 2021 May 14.

Department of Oral Surgery, Government Dental College, Raipur, Chhattisgarh, India.

Oral metastasis, although rare, tends to involve jawbones, particularly the posterior region of the mandible, and involvement of oral soft tissues, even when less likely, is most often seen on the gingiva and tongue. Clinically, the soft-tissue masses tend to mimic pyogenic granuloma, peripheral giant cell granuloma or an epulis and thus are difficult to diagnose and identify. The jaw bone is preferred by prostate carcinoma as a metastatic target. Read More

J Med Virol 2021 11 6;93(11):6089-6099. Epub 2021 Jul 6.

Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Birjand University of Medical Sciences, Birjand, Iran.

The role of human papillomavirus (HPV) in the development of oral lesions is controversial. There has been no comprehensive study about HPV prevalence in Iran. This systematic review and meta-analysis were aimed at finding HPV prevalence of oral lesions and normal oral mucosa in Iran. Read More

J Indian Soc Periodontol 2021 May-Jun;25(3):258-261. Epub 2021 May 3.

Department of Periodontology and Oral Implantology, Surendera Dental College and Research Institute, Sri Ganganagar, Rajasthan, India.

Inflammatory fibrous hyperplasia, pyogenic granuloma, peripheral ossifying fibroma, irritational fibroma (IF), peripheral giant cell granuloma, etc., are the different types of reactive gingival lesions that may occur in response to mild chronic irritation associated with subgingival factors, root remnant, iatrogenic factors, and trauma. Gingival IF is one of the most common reactive lesions and is usually sessile in nature, and its size is usually not more than 1. Read More

J Indian Soc Periodontol 2021 May-Jun;25(3):254-257. Epub 2021 May 3.

Department of Oral Medicine and Radiology, Nair Hospital Dental College, Dr. A. L Nair Road, Mumbai Central, Mumbai, Maharashtra, India.

Capillary hemangiomas and pyogenic granuloma (PG) are well-recognized benign entities of the oral cavity which are vascular in origin. PG is said to have a predilection for gingival area, whereas capillary hemangioma involves the lips, cheek, and tongue. They may mimic more serious conditions such as malignancies making the clinical diagnosis quite challenging. Read More

Indian J Otolaryngol Head Neck Surg 2021 Jun 15;73(2):167-173. Epub 2020 Jul 15.

Department of Oral Medicine and Radiology, Government Dental College and Hospital, Ahmedabad, Gujarat India.

Sclerotherapy is a targeted elimination of small vessels, varicose veins, and vascular anomalies by the injection of a sclerosant. Sclerotherapy aims to damage the vessel wall and transform it into fibrous tissue. The present study was conducted to evaluate the efficacy of a sclerosing agent 3% polidocanol in the treatment of vascular lesions and pyogenic granuloma. Read More

Am J Case Rep 2021 Jun 19;22:e929690. Epub 2021 Jun 19.

Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy.

BACKGROUND A pyogenic granuloma is an inflammatory exophytic lesion that can occur in the oral cavity. Numerous factors are involved in the etiology of the lesion and can lead to the tissue proliferation underlying the lesion's characteristic appearance. The main treatment is surgical excision with careful curettage of the surrounding tissues. Read More