Med Oral Patol Oral Cir Bucal 2018 Apr 22. Epub 2018 Apr 22.

41 Amyclon Str, 11142 Lamprini, Athens, Greece

Background: To describe the incidence, demographic and clinical features of 1187 localized gingival enlargements.

Material And Methods: 1187 cases of localized gingival enlargements diagnosed during a 20-year period were retrospectively collected. The patients gender and age, as well as the main clinical features of the tumors were retrieved from the biopsy report forms. Read More

Clin Case Rep 2018 Apr 27;6(4):690-693. Epub 2018 Feb 27.

Department of PathologyChitwan Medical College Teaching HospitalP.O. Box 42, Bharatpur 10ChitwanNepal.

Pyogenic granuloma is a benign vascular neoplasm of the oral cavity that usually presents as a small nodular lesion, the gingiva being the commonest site. Occasionally it occurs at uncommon sites with unusual sizes. Here we describe two cases of oral pyogenic granulomas that had an unusual presentation. Read More

Dermatol Online J 2018 Feb 15;24(2). Epub 2018 Feb 15.

Department of Biosciences and Oral Diagnosis, Institute of Science and Technology, São Paulo State University (Unesp); São José dos Campos, SP, Brazil.

Intravascular papillary endothelial hyperplasia (IPEH) is an unusual benign, non-neoplastic vascular lesion that usually occurs in skin, but is uncommon in the oral cavity. Herein, we review the pertinent literature of oraiiPEH and report a new mixed form. A 61-year- old man presented with an ulcerated nodule in the lingual portion of the gingiva related to the left mandibular canine. Read More

Medicine (Baltimore) 2018 Mar;97(13):e9934

Piracicaba Dental School, University of Campinas, Piracicaba, São Paulo.

Rationale: Oral metastases occur more commonly in bone, but can also manifest in soft tissues and eventually resemble a reactive lesion. Few cases of oral metastases mimicking reactive lesions in soft tissues have been reported to date.

Patient Concerns: We report a metastasis of gastric carcinoma (GC) to the oral mucosa without bone involvement in a 43 yom clinically and microscopically mimicking a reactive lesion. Read More

J Oral Maxillofac Pathol 2018 Jan;22(Suppl 1):S102-S107

Division of Oral and Maxillofacial Pathology, Columbia University Medical Center, New York, USA.

Tumor metastasis to the oral cavity is rare and is usually an indication of late-stage disease and poor prognosis. While, there are reports of renal cell carcinoma (RCC) metastatic to oral cavity, vast majority of them are to the jaw. Herein, we present a case of a 78-year-old woman with RCC metastasis limited to the oral soft tissue without any bone involvement. Read More

J Indian Soc Periodontol 2017 Jul-Aug;21(4):258-263

Department of Oral and Maxillofacial Pathology and Microbiology, SDM College of Dental Sciences and Hospital, Dharwad, Karnataka, India.

Objective: This study reviews, analyzes, and compares the demographic data, histopathological features and discusses the treatment and prognosis of reactive lesions (RLs).

Materials And Methods: Retrospective study was performed on the departmental archives from July 2006 to July 2016 (total 5000 cases) comprising of 659 cases of RLs of the oral cavity. The recorded data included age, gender, size, site, duration, habits, etiology, histopathological diagnosis, treatment, and prognosis. Read More

Indian J Dent Res 2018 Jan-Feb;29(1):61-66

Department of Community Dentistry, MIDSR Dental College, Latur, India.

Context: The reactive lesions are relatively common in the oral cavity because of the frequency with which the tissues are injured. They often result from a known stimulus or injury such as dental plaque, calculus, or foreign material.

Aims: : The aim of this study was to review the clinicopathologic features of reactive hyperplastic lesions (RHLs) of the oral cavity at MIDSR, Dental College and Hospital, Latur, Maharashtra, and to compare these data with those of previously reported studies. Read More

J Indian Soc Periodontol 2017 May-Jun;21(3):241-244

Department of Periodontology, Dayananda Sagar College of Dental Sciences, Bengaluru, Karnataka, India.

Pyogenic granuloma (PG) is a nonneoplastic, tumor-like growth commonly seen in the oral mucosa or skin. Although nonpathological, its existence might lead to complications such as secondary infections or diastema formation. Hence, surgical removal of the growth seems mandatory. Read More

J Oral Maxillofac Pathol 2017 Sep-Dec;21(3):415-420

Department of Oral Pathology and Microbiology, Government Dental College, Kottayam, Kerala, India.

Hemangioendothelioma commonly occurs in the superficial or deep soft tissue of the extremities, lungs, liver, bone and lymph nodes, with oral cavity being a rare location. It is usually benign but can show variable grades of malignancy. According to the histological presentation, hemangioendothelioma has been classified as epithelioid, Kaposiform, hobnail (Dabska-Retiform), epithelioid sarcoma like and composite. Read More

J Oral Maxillofac Pathol 2017 Sep-Dec;21(3):382-386

Department of Periodontics, Post Graduate Institute of Dental Sciences, Pt. B.D. Sharma University of Health Sciences, Rohtak, Haryana, India.

Background And Objective: Reactive proliferations of oral cavity comprise pyogenic granuloma (PG), fibrous hyperplasia (FH), peripheral ossifying fibroma (POF), and peripheral giant-cell granuloma (PGCG). They often pose diagnostic challenges due to their overlapping clinical and histopathological features. This study was conducted to determine the frequency and clinicopathological correlation of reactive hyperplastic lesions in the oral cavity reported in our institute and compared it with other previous studies. Read More

Otolaryngol Clin North Am 2018 Feb;51(1):89-97

Department of Plastic and Oral Surgery, Vascular Anomalies Center, Boston Children's Hospital, Harvard Medical School, 300 Longwood Avenue Boston, MA, 02115, USA. Electronic address:

Vascular tumors are benign neoplasms, which result from proliferating endothelial cells. These lesions present during infancy or childhood, may affect any location, and exhibit postnatal growth. Local complications include bleeding, tissue destruction, and pain whereas systemic sequelae include thrombocytopenia, congestive heart failure, and death. Read More

Med Oral Patol Oral Cir Bucal 2017 Nov 1;22(6):e686-e693. Epub 2017 Nov 1.

Department of Surgical Sciences, University of Turin, CIR - Dental School, Oral Medicine Section, Via Nizza 230, 10126 Turin, Italy,

Background: The diagnosis and treatment of a variety of non-plaque related gingival diseases have become an integrated aspect of everyday dentistry. The aim of this study was to analyse the relationship between clinical appearance and histopathological features of gingival lesions in a large Northern Italian population.

Material And Methods: A retrospective study of 788 cases of gingival and alveolar mucosal biopsies was set up. Read More

J Craniofac Surg 2018 Jan;29(1):e49-e50

School of Medicine, University of Seville, Virgen del Rocio University Hospital, Seville, Spain.

Pregnancy pyogenic granuloma is considered a benign common growth that usually develops on the gingiva in the second and third trimester of gestation, in response to local irritation, trauma or hormonal factors. Here, the authors report a case of a primigravida who presented an extragingival pyogenic granuloma with a rapid progression in the post-partum. The occurrence on the lower lip in the first few days after delivery was a relatively rarity in the present case which provoked a meaningful state of anxiety and cancerophobia to the female. Read More

J Contemp Dent Pract 2017 Oct 1;18(10):981-985. Epub 2017 Oct 1.

Department of Periodontology, Lake Erie College of Osteopathic Medicine, School of Dental Medicine, Bradenton, Florida, USA, Phone: +9414051506, e-mail:

Introduction: The aim of this study is to describe a case of a melanotic macule found in conjunction with a giant cell fibroma (GCF). For oral pigmented lesions without an identifiable etiologic factor, critical factors in determining the differential diagnosis are clinical history, symmetry, and uniformity of the lesions. Potential differential diagnosis includes racial pigmentation, endocrine disturbance, Peutz-Jeghers syndrome, trauma, hemochromatosis, oral malignant melanoma, or idiopathic etiology and melanotic macules. Read More

Int J Clin Pediatr Dent 2017 Apr-Jun;10(2):188-192. Epub 2017 Jun 1.

Professor and Principal, Department of Pedodontics and Preventive Dentistry, Eklavya Dental College, Kothputli, Rajasthan, India.

Soft tissue laser, such as diode and Nd:YAG lasers were initially used in soft tissue lesions because of its increased success rate. It was because of the fact that these lasers were well-absorbed by chromophores, such as hemoglobin and melanin which are found abundant in the oral mucosa. The introduction of erbium family in 1990 comprising the Er:YAG and Er,Cr:YSGG lasers made the hard tissue laser a boon for dentistry. Read More

Cancer Sci 2017 Nov 15;108(11):2295-2305. Epub 2017 Sep 15.

Division of Cancer Biology, National Cancer Center Research Institute, Tokyo, Japan.

Human angiosarcoma is a rare malignant vascular tumor associated with extremely poor clinical outcome and generally arising in skin of the head and neck region. However, little is known about the molecular pathogeneses and useful immunohistochemical markers of angiosarcoma. To investigate the mechanisms of angiosarcoma progression, we collected 85 cases of human angiosarcoma specimens with clinical records and analyzed ISO-HAS-B patient-derived angiosarcoma cells. Read More

Saudi Dent J 2017 Jul 3;29(3):129-134. Epub 2017 May 3.

Maxillofacial Surgery and Diagnostic Sciences Department, College of Dentistry, King Saud bin Abdulaziz University for Health Sciences, Riyadh 14611, Saudi Arabia.

Kaposi Sarcoma (KS) is an intermediate neoplasm affecting the endothelial cells of mucous membranes and skin. It arises most commonly among HIV-infected individuals. We present an intra-oral KS in an 80-year-old Saudi male patient, who is HIV-seronegative, non-immunosuppressed, and with no history of organ transplantation. Read More

Ear Nose Throat J 2017 Jul;96(7):240

Department of Pathology, Southern California Permanente Medical Group, Woodland Hills Medical Center, Woodland Hills, CA, USA.

JAMA 2017 Jul;318(3):293-294

Banner University Medical Center, University of Arizona, Tucson.

J Clin Diagn Res 2017 May 1;11(5):ZC25-ZC28. Epub 2017 May 1.

Postgraduate Student, Department of Oral Pathology, St. Joseph Dental College, Eluru, Andhra Pradesh, India.

Introduction: Angiogenesis is vital in the aetiology and pathogenesis of a number of pathological processes that include solid reactive lesions like pyogenic granuloma and chronic inflammatory disorders like periapical granuloma. Vascular Endothelial Growth Factor (VEGF) is a potent proangiogenic cytokine secreted by many cell types which present several pivotal functions in physiologic and pathologic angiogenesis.

Aim: The aim of the present study was to evaluate and compare the expression of VEGF in oral Pyogenic Granuloma (PG) and Periapical Granuloma (PAG) and also to correlate with the inflammatory cell infiltrate. Read More

Exp Mol Pathol 2017 08 22;103(1):9-13. Epub 2017 May 22.

Postgraduate Program, Oral Pathology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.

Objectives: To evaluate cases diagnosed as "oral hemangiomas" based on the immunohistochemical expression of human glucose transporter protein (GLUT-1) and on histopathological features, and to investigate whether the classification proposed by the ISSVA was used correctly to classify these lesions.

Material And Methods: All cases stored in the archives of an Oral Pathology Service and diagnosed as "oral hemangiomas" were reviewed. Seventy-seven cases were analyzed regarding the expression of GLUT-1. Read More

Stomatologiia (Mosk) 2017;96(2):33-35

Peoples' Friendship University of Russia, Moscow, Russia.

The paper presents an example of differential diagnostic studies for pyogenic granuloma and oral squamous cell carcinoma (SCC). In the described case immunohistochemistry with antibodies to Ki-67 and Gli1 was used as conventional histological procedure proved to be inconvenient for adequate diagnostics. The immunohistochemical study established increased proliferative activity of epithelial cells specific both pyogenic granuloma and oral SCC, but intensive Gli1 protein expression in membranes and cytoplasm of epithelial cells with malignant transformation allowed differentiation of these neoplasms. Read More

J Craniofac Surg 2017 Jun;28(4):e398-e399

*Department of Pathology, Faculty of Medicine †Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Gaziantep University, Gaziantep ‡Department of Pathology, Faculty of Medicine, TOBB Economics and Technology, Ankara, Turkey.

Metastatic tumors rarely occur in the oral cavity. The most common of the oral metastases are lung cancers in males, and breast and genital cancers in females. The most common primary tumor metastasis to the oral cavity is from the lung, kidney, liver, prostate, and colorectal cancers. Read More

J Oral Maxillofac Pathol 2017 Jan-Apr;21(1):180

Department of Oral and Maxillofacial Pathology, Navodaya Dental College, Raichur, Karnataka, India.

Background: In the literature, many studies were attempted to analyze the distribution of oral reactive lesions in terms of age, gender and location. However, very few studies have focused on the detailed histopathological features of these reactive lesions of oral cavity. Thus, the purpose of this paper is to document the occurrence, distribution and various histopathological features of reactive gingival lesions. Read More

Saudi Med J 2017 Apr;38(4):405-412

Department of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jazan University, Jazan, Kingdom of Saudi Arabia. E-mail.

Objectives: To report the prevalence and types of biopsied oral and maxillofacial lesions (OMLs) in South-Western (Jazan Province) region, , Kingdom of Saudi Arabia (KSA). Methods: This retrospective study was based on the retrieval of clinicopathological data for a period of 6 years between January 2009 and December 2014. These  data were obtained between October 2014 and June 2015 from the histopathology records of King Fahad Central Hospital, Jazan, KSA, which is the only referral center for biopsy services. Read More

J Coll Physicians Surg Pak 2017 Mar;27(3):S28-S29

Department of Oral and Maxillofacial Pathology, NIMS Dental College, Jaipur, India.

Odontogenic myxomas are rare odontogenic tumors of jaw characterised by accumulation of mucoid ground substance with little collagen. Peripheral odontogenic myxoma (POM) is extra-osseous variant of odontogenic myxomas, occurring solely in the soft tissue covering the tooth bearing portion of jaws. POM is exceedingly rare, less than 10 cases have been published till date. Read More

Hautarzt 2017 Mar;68(3):181-186

Department of Dermatology, CHU of Sart Tilman, University of Liège, 4000, Liège, Belgien.

This review on herpes simplex virus type I and type II (HSV-I, HSV-II) summarizes recent developments in clinical manifestations and treatment interventions for primary and recurrent orolabial and genital herpes, as well as those regarding vaccination issues. Among the clinical presentations, the relationship between pyogenic granuloma and chronic HSV-I infection; HSV-related folliculitis; verrucous HSV-I and HSV-II lesions; the role of recurrent HSV-I infection in burning mouth syndrome; HSV-I and HSV-II infection of the periareolar area; zosteriform HSV; the "knife-cut sign"; and the preferential colonization and infection of preexisting dermatoses by HSV-I or HSV-II are discussed. The usual antiviral treatment regimens for primary and recurrent orolabial and genital herpes are compared to short-term and one-day treatment options. Read More

Hautarzt 2017 Dec;68(Suppl 1):1-5

Department of Dermatology, CHU of Sart Tilman, University of Liège, 4000, Liège, Belgium.

This review on herpes simplex virus type I and type II (HSV‑I, HSV‑II) summarizes recent developments in clinical manifestations and treatment interventions for primary and recurrent orolabial and genital herpes, as well as those regarding vaccination issues. Among the clinical presentations, the relationship between pyogenic granuloma and chronic HSV‑I infection; HSV-related folliculitis; verrucous HSV‑I and HSV‑II lesions; the role of recurrent HSV‑I infection in burning mouth syndrome; HSV‑I and HSV‑II infection of the periareolar area; zosteriform HSV; the "knife-cut sign"; and the preferential colonization and infection of preexisting dermatoses by HSV‑I or HSV‑II are discussed. The usual antiviral treatment regimens for primary and recurrent orolabial and genital herpes are compared to short-term and one-day treatment options. Read More

J Cutan Pathol 2017 May 16;44(5):451-455. Epub 2017 Feb 16.

School of Dentistry, University of São Paulo, São Paulo, São Paulo, Brazil.

Background: Although not rare, vascular lesions occurring in the lips sometimes poses a difficult in properly diagnosing and handling them. In this study, vascular lesions occurring in the lips were retrieved from an Oral Pathology Service.

Methods: Among 5600 biopsies, 131 cases were found. Read More

J Dent Res Dent Clin Dent Prospects 2016 21;10(4):241-246. Epub 2016 Dec 21.

Postgraduate Student, Biotechnology Research Center and Department of Orthodontics, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.

Reliable immunohistochemical assays to assess the definitive role of mast cells (MCs) and angiogenesis in the pathogenesis of oral reactive lesions are generally not available. The aim of the present study was to evaluate mast cell counts (MCC) and microvessel density (MVD) in oral reactive lesions and determine the correlation between MCC and MVD. Seventy-five cases of reactive lesions of the oral cavity, including pyogenic granuloma, fibroma, peripheral giant cell granuloma, inflammatory fibrous hyperplasia, peripheral ossifying fibroma (15 for each category) were immunohisto-chemically stained with MC tryptase and CD31. Read More

J Obstet Gynaecol Res 2017 Jan;43(1):16-22

Clinica Odontologica, Federal University of Maranhao, São Luís, Brazil.

The aims of this literature review are: to depict the main oral diseases that are related to pregnancy; to clarify some of the possible systemic mechanisms that are associated with these changes; and to address issues about oral care during pregnancy. A woman's organs undergo various physiological, neurological, and hormonal changes during pregnancy. Such changes occur gradually and are essential for the development of the fetus, providing what is needed for tissue formation and establishment of reserves for uterine and fetal life. Read More

J Obstet Gynaecol 2017 May 26;37(4):537-538. Epub 2016 Dec 26.

a Department of Otolaryngology, Department of Clinical Sciences and Community Health , Fondazione I.R.C.C.S. Ca' Granda, Ospedale Maggiore Policlinico, University of Milan , Milan , Italy.

Mycopathologia 2017 Jun 21;182(5-6):549-554. Epub 2016 Dec 21.

Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, 200040, China.

Infections caused by Trichophyton rubrum are very common in dermatological disease. It most often appears as superficial cutaneous mycosis, such as tinea manuum, tinea pedis, and tinea corporis. However, deep infection caused by T. Read More

Braz Dent J 2016 Oct-Dec;27(6):781-786

Department of Bioscience and Oral Diagnosis, São Paulo State University (UNESP), Institute of Science and Technology, São José dos Campos, SP, Brazil.

Adenosquamous carcinoma is an aggressive variant of squamous cell carcinoma. This report describes a case of adenosquamous carcinoma with clinical features of a benign lesion and discusses the differential diagnoses, especially regarding histopathological and immunohistochemical analyses. A 45-year-old male was referred to our outpatient clinic complaining about a rapid-growing enlargement in hard palate. Read More

J Clin Diagn Res 2016 Oct 1;10(10):ZD28-ZD29. Epub 2016 Oct 1.

Senior Lecturer, Department of Pedodontics and Preventive Dentistry, IDST , Modinagar, Ghaziabad, Uttar Pradesh, India .

Natal teeth are teeth present in the oral cavity at the time of birth. It is extremely rare to find natal teeth in association with pathological conditions of the oral cavity. Pyogenic granuloma is a type of inflammatory hyperplasia that appears as an over exuberant connective tissue response to a stimulus or injury, in the present case the injurious agent is the natal tooth. Read More

J Clin Diagn Res 2016 Oct 1;10(10):ZD10-ZD12. Epub 2016 Oct 1.

Senior Lecturer, Department of Oral and Maxillofacial Pathology, Sri Venkateshwara Dental College and Hospital , Chennai, Tamil Nadu, India .

Pyogenic granuloma is a tissue overgrowth which commonly develops as a response to irritation or trauma which is usually localized. Though gingiva is said to be the common site, it also can occur on lip, tongue and buccal mucosa. Pathogenesis is unclear but trauma, infection and hormonal imbalance are attributed as reasons for occurrence. Read More

Head Neck Pathol 2017 Dec 22;11(4):525-530. Epub 2016 Nov 22.

Department of Oral and Maxillofacial Surgery, University of Washington School of Dentistry, Seattle, WA, USA.

The pseudomyogenic hemangioendothelioma (PMH) is a low-grade malignant vascular neoplasm of different tissue planes including skin and soft tissue. Primary tumors in the skeletal muscle and bone have also been diagnosed. The PMH was introduced into the WHO classification of tumors of soft tissue and bone in 2013. Read More

Saudi Med J 2016 Dec;37(12):1395-1400

Department of Dentistry, Prince Sultan Military Medical City, Riyadh, Kingdom of Saudi Arabia. E-mail.

Pyogenic granuloma (PG) is a common, acquired, benign vascular reactive proliferation that typically develops as a small erythematous papule on the skin or oral mucosal surface. Oral PG is often caused by constant low-grade infection, minor trauma, poor oral hygiene, and due to hormonal disturbances. It shows a striking predilection for the gingiva. Read More

J Craniofac Surg 2017 Mar;28(2):e185-e186

*Department of Pathology and Clinical Propedeutics †Oral Oncology Center, Araçatuba Dental School, Univ Estadual Paulista-UNESP, Araçatuba, Brazil.

Pyogenic granuloma is a common cause of growth of soft tissue in the oral cavity, especially in the gingiva. It is mainly associated with local and chronic irritants besides hormonal changes during pregnancy. Here, the authors present an unusual patient of an extra-gingival pyogenic granuloma with large dimensions and displacing teeth arising in a male patient. Read More

Case Rep Surg 2016 25;2016:6290424. Epub 2016 Sep 25.

Department of Cardiothoracic Surgery, Castle Hill Hospital, Cottingham, UK.

Lobular capillary haemangioma (LCH), previously known as pyogenic granuloma, is a benign vascular lesion commonly found within the oral and nasal cavity. However, it is rarely encountered within the trachea, where presenting features include recurrent haemoptysis, cough, and wheeze. We here describe a case of a 7 mm tracheal LCH in a 56-year-old woman, which was successfully resected at interventional bronchoscopy using biopsy forceps. Read More

J Oral Maxillofac Pathol 2016 Sep-Dec;20(3):510-517

Department of Oral and Maxillofacial Pathology and Microbiology, M.A. Rangoonwala College of Dental Sciences and Research Center, Pune, Maharashtra, India.

The non-Hodgkin's lymphoma (NHLs) is a diverse group of lymphoid neoplasms, prevalence of which increased since three decades. NHL is diverse in the manner of presentation, response to various treatment and prognosis. NHL usually involves not only lymph nodes but also extranodal sites. Read More

Head Neck Pathol 2017 Sep 5;11(3):404-412. Epub 2016 Oct 5.

Department of Oral and Maxillofacial Surgery, University of Washington School of Dentistry, B-204 Magnuson Health Sciences Center, 1959 NE Pacific Street, Box 357133, Seattle, WA, 98195, USA.

Four cases of cutaneous S-100 negative granular cell tumor were described in 1991. Until now, only 3 cases of oral involvement have been documented in English literature. Two additional cases of oral S-100 negative granular cell tumor are described. Read More

J Coll Physicians Surg Pak 2016 Jul;26(7):631-2

Department of Prosthodontics Crown and Bridge, NIMS Dental College, Jaipur, India.

Leiomyomas are benign soft tissue neoplasms that arise from smooth muscles. Three distinctive patterns of leiomyoma have been described as piloleiomyomas, angioleiomyomas and genital leiomyomas. Here in, we report the case of 39-year male with chief complain of growth on his lower left front region of the jaw. Read More

Pathol Res Pract 2016 Sep 18;212(9):761-6. Epub 2016 May 18.

Laboratory of Oral Surgical Pathology, School of Dentistry, Federal University of Bahia, Salvador, Bahia, Avenida Araújo Pinho, 62, Canela, Salvador, Bahia 40110-150, Brazil. Electronic address:

In view of the similarity of clinicopathological features between reactive lesions of the oral cavity, the objective of the present study was to investigate the density of MCs (mast cells) and microvessels in a series of these lesions. Thirty-seven cases of reactive lesions including fibrous hyperplasia (FH, n=10), inflammatory fibrous hyperplasia (IFH, n=10), peripheral giant cell lesion (PGCL, n=10) and lobular capillary hemangioma (LCH, n=7) were investigated using immunohistochemistry for mast cell tryptase and CD34. For comparative purposes, central giant cell lesions (CGCL, n=5) were included. Read More

J Clin Diagn Res 2016 May 1;10(5):ZC06-8. Epub 2016 May 1.

Professor, Department of Oral Pathology and Microbiology, Babu Banarasi Das College of Dental Sciences , Lucknow, India .

Introduction: Mast cells are large granular cells that have classically been related to neutrophil stimulation during early step of inflammation.

Aim: The objective of this work was to identify the incidence of mast cells in inflammatory lesions like periapical granuloma, pyogenic granuloma, gingival hyperplasia. 1. Read More

Photomed Laser Surg 2016 Sep 15;34(9):425-31. Epub 2016 Jul 15.

1 Department of Oral Surgery and Orthodontics, Medical University Graz , Graz, Austria .

Objective: This article reports the CO2 laser excision of a pyogenic granuloma related to dental implants and reviews the current literature on this pathology in association with dental implants.

Background Data: Five publications describe pyogenic granulomas related to dental implants, and a further one describes the removal of such a lesion with an Er:YAG laser; removal with a CO2 laser is not reported.

Patients And Methods: A 67-year-old male patient presented with a hyperplastic gingival lesion around two implants in the left lower jaw. Read More

Case Rep Gastrointest Med 2016 15;2016:4398401. Epub 2016 Jun 15.

Department of Pathology, Saint Louis University School of Medicine, Saint Louis, MO 63104, USA.

Pyogenic granuloma (PG), more accurately known as lobular capillary hemangioma, is a benign vascular tumor that usually occurs in the skin or oral mucosa. This lesion is rarely reported in the gastrointestinal tract but is known to bleed if not resected. We herein describe a case series with the clinical, endoscopic, and histologic findings of four cases of gastrointestinal PG at our institution. Read More

Eur J Dent 2016 Jul-Sep;10(3):432-4

Department of Periodontology, Faculty of Dentistry, Erciyes University, Kayseri, Turkiye.

The total removal of a lesion via excisional biopsy causes gingival recession, resulting in dentin hypersensitivity and esthetical problems. In this case report, a gingival recession defect resulting from an excisional biopsy was treated with a free gingival grafting procedure performed during the same appointment, and its 12-year follow-up was presented. A 44-year-old female patient was presented to our clinic with a firm, pedunculated, red gingival enlargement located on the labial surface of lower incisors. Read More

Case Rep Dent 2016 12;2016:1323798. Epub 2016 Jun 12.

Department of Periodontics & Implantology, College of Dental Surgery, BP Koirala Institute of Health Sciences, Dharan, Sunsari 56700, Nepal.

Background. Pyogenic granuloma is a reactive tumor-like lesion commonly affecting the oral cavity. These lesions usually appear as localized solitary nodule with a sessile or pedunculated base and colour varying from red, purplish, or pink, depending on the vascularity of the lesion. Read More

J Lasers Med Sci 2016 7;7(1):56-61. Epub 2016 Jan 7.

Gazi University, School of Dentistry, Department of Oral Surgery, Ankara, Turkey.

Introduction: Pyogenic granuloma (PG) is a prevalent inflammatory hyperplasia of skin and oral mucosa which is often caused by constant low-grade local irritation, traumatic injury or hormonal factors. In many cases, gingival irritation and inflammation due to poor oral hygiene are precipitating factors. Oral PG occurs predominantly on the gingiva, but it is also encountered on the lips, tongue, buccal mucosa and rarely on the hard palate. Read More