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    40 results match your criteria Oral Melanoacanthoma

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    Oral pigmentations in physiologic conditions, post inflammatory affections and systemic diseases.
    G Ital Dermatol Venereol 2017 Apr 19. Epub 2017 Apr 19.
    Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy -
    Melanocytes are found throughout the oral mucosa but usually go unnoticed because of their relatively low level of pigment production. When focally or generally active in pigment production or proliferation they may be responsible for several affections in the oral mucosae ranging from physiologic pigmentation, systemic diseases to malignant neoplasms. The diagnosis of oral pigmentations (OP) is usually challenging for the physician, but a careful examination of the oral cavity may reveal the first manifestation of underlying systemic diseases. Read More

    Pathogenesis and clinicohistopathological caractheristics of melanoacanthoma: A systematic review.
    J Clin Exp Dent 2016 Jul 1;8(3):e327-36. Epub 2016 Jul 1.
    Professor of Oral Surgery. Co-Head of Master in Oral Surgery. University of Seville.
    Introduction: The melanoacanthoma is a rare benign pigmented tumor, characterized by a fast radial growth and clinical behavior similar to melanoma. Color changes in oral mucosa and dermis are consequence of increased melanocyte activity as response to an irritant factor. There is a vast phenotypic variety. Read More

    Pigmented lesion with characteristics of malignancy: a case report.
    Gen Dent 2013 Sep-Oct;61(6):e2-5
    Pigmentations of the oral mucosa include a range of lesions or conditions that manifest as changes in the color of oral tissues; these changes may show melanocytic activity. A melanotic macule is a small, well-circumscribed melanocytic benign lesion. It can occur on the lips and intraorally and ranges in color from brown to black. Read More

    Immunohistochemical features of multifocal melanoacanthoma in the hard palate: a case report.
    BMC Res Notes 2013 Jan 28;6:30. Epub 2013 Jan 28.
    Department of Biosciences and Oral Diagnosis, São José dos Campos Dental School, São Paulo State University (UNESP), São José dos Campos, São Paulo, Brazil.
    Background: Melanoacanthoma (MA) has been described in the oral mucosa as a solitary lesion or, occasionally, as multiple lesions. MA mainly affects dark skinned patients and grows rapidly, showing a plane or slightly raised appearance and a brown to black color. The differential diagnosis includes oral nevi, amalgam tattoos, and melanomas. Read More

    Oral melanoacanthoma of a rare intraoral site: case report and review of literature.
    Int J Clin Pediatr Dent 2013 Jan 26;6(1):40-3. Epub 2013 Apr 26.
    Ex-Senior Lecturer, Department of Orthodontics and Dentofacial Orthopedics, Indira Gandhi Institute of Dental Sciences, Puducherry India.
    Oral melanoacanthoma is rare pigmented mucosal lesion that presents most commonly on the buccal mucosa, characterized by sudden appearance and rapid radial growth, thus clinically mimicking malignant melanoma. It was originally described as a mixed tumor of melanocytes and keratinocytes, but appears to be a reactive process; formed in areas prone to trauma, and regressing after the removal of trauma or incomplete excision. The clinical appearance of oral melanoacanthoma is nondiagnostic, and biopsy is mandatory to rule out malignancy. Read More

    Oral melanoacanthoma: A rare case of diffuse oral pigmentation.
    J Oral Maxillofac Pathol 2012 Sep;16(3):441-3
    Department of Oral and Maxillofacial Pathology, Vaidik Dental College and Research Centre, Daman, India.
    The clinical presentation of diffuse pigmentation can be alarming to the patient as well as the clinician. A histopathologic examination of a pigmented lesion is necessary in most of the cases in the oral cavity. Oral melanoacanthoma is a very rare diffuse pigmentation with no specific treatment required. Read More

    Oral pigmented lesions: Clinicopathologic features and review of the literature.
    Med Oral Patol Oral Cir Bucal 2012 Nov 1;17(6):e919-24. Epub 2012 Nov 1.
    Oral Pathology Division, Department of Oral Diagnosis, Piracicaba Dental School, State University of Campinas, Piracicaba, Brazil.
    Diagnosis of pigmented lesions of the oral cavity and perioral tissues is challenging. Even though epidemiology may be of some help in orientating the clinician and even though some lesions may confidently be diagnosed on clinical grounds alone, the definitive diagnosis usually requires histopathologic evaluation. Oral pigmentation can be physiological or pathological, and exogenous or endogenous. Read More

    Multifocal oral melanoacanthoma and melanotic macula in a patient after dental implant surgery.
    J Am Dent Assoc 2011 Jul;142(7):817-24
    Department of Oral Surgery and Implant Dentistry, School of Dentistry, University of Granada, Spain.
    Background: Oral melanoacanthoma (OMA) is an uncommon, reactive, pigmented mucocutaneous lesion. It is a rapidly growing, well-circumscribed, small, brown-to-black, solitary or multifocal macule that is characterized histopathologically by proliferation of keratinocytes and pigment-laden dendritic melanocytes.

    Case Description: At the end of a one-month healing period after dental implant surgery, a 63-year-old white woman had pigmented lesions at different oral mucosal sites (hard palate, buccal mucosa and left maxillary tuberosity) that showed macrophages exhibiting iron and melanin in multiple areas of the lamina propria. Read More

    Gingival melanoacanthoma: case report and discussion of its clinical relevance.
    Quintessence Int 2011 Mar;42(3):253-8
    Department of Oral Diagnostic Sciences, School of Dental Medicine, State University of New York at Buffalo, Buffalo, NY 14214, USA.
    Oral melanoacanthoma is an uncommon reactive condition that appears as a solitary pigmented lesion and is most often found on the buccal mucosa. For it to appear in the gingiva is extremely rare--only 11 cases are reported in the literature. This article presents a case of gingival melanoacanthoma and reviews the previously published cases. Read More

    Oral melanoacanthoma in an adolescent.
    Pediatr Dermatol 2010 Jul-Aug;27(4):384-7
    Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, Baltimore, Maryland 21201-1586, USA.
    The etiopathogenesis of oral pigmentation is diverse. One such process is the oral melanoacanthoma, a reactive, melanocytic lesion, infrequently found in the pediatric subpopulation. To extend the knowledge of this lesion, we provide a case of gingival melanoacanthoma in a 17-year-old male patient. Read More

    Multifocal diffuse oral melanoacanthoma: a case report.
    J Oral Sci 2009 Sep;51(3):463-6
    Department of Oral Pathology, School of Dentistry, University of São Paulo, Brazil.
    Oral melanoacanthoma (OMA) is a rare benign lesion characterized by colonization of acanthotic epithelium by dendritic melanocytes. Although its pathogenenesis remains uncertain, its clinical behavior and spontaneous remission suggest a non-neoplastic nature. Clinically, it may present as a solitary or multifocal lesion; however these two variants exhibit different features. Read More

    Multifocal melanoacanthoma of the gingiva and hard palate.
    J Periodontol 2009 Mar;80(3):527-32
    Department of Oncology and Diagnostic Sciences, Baltimore College of Dental Surgery, Dental School, University of Maryland, Baltimore, 650 W. Baltimore St., Baltimore, MD 21201-1586, USA.
    Background: Gingival melanoacanthoma is an uncommon reactive lesion, typically appearing as a solitary pigmented macule. This article reports a previously undescribed case of multifocal melanoacanthoma affecting the maxillary and mandibular gingiva and the hard palate. A literature review of melanoacanthoma of the gingiva is also provided. Read More

    Oral melanoacanthoma: a case report and review of the literature.
    J Med Case Rep 2009 Jan 13;3:11. Epub 2009 Jan 13.
    Department of Oral and Maxillofacial Pathology, Ragas Dental College and Hospital, East Coast Road, Chennai, Tamilnadu 600119, India.
    Introduction: Oral melanoacanthoma is a rare, benign pigmented lesion characterized clinically by the sudden appearance and rapid growth of a macular brown-black lesion and histologically by acanthosis of the superficial epithelium and proliferation of dendritic melanocytes.

    Case Presentation: We present a case report of oral melanoacanthoma in a 24-year-old Asian Indian man. He presented with an intra-oral brown macular lesion on the left buccal mucosa with a duration of one and a half months. Read More

    Reactive hyperplasias,precancerous and malignant lesions of the oral mucosa.
    J Dtsch Dermatol Ges 2008 Mar;6(3):217-32
    Institute of Dermatohistology, Heidelberg, Germany.
    The oral cavity contains many organs and tissues compressed in a small area. Accordingly oral tumors have a wide variety of appearances. Reactive hyper-plastic lesions include epulis,morsicatio,traumatic ulcer or palatal hyperplasia. Read More

    Solitary and multifocal oral melanoacanthoma.
    Int J Dermatol 2007 Dec;46(12):1232-6
    Department of Oral Pathology and Oral Medicine, Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel.
    Background: Oral melanoacanthoma is a rare pigmented lesion characterized by sudden appearance and rapid radial growth, mimicking malignant melanoma. Oral melanoacanthoma may present as a solitary or multifocal lesion; however, the characteristics of these two clinical variants have never been addressed. In this study, we present an unusual case of multifocal oral melanoacanthoma and analyze cases of oral melanoacanthoma reported in the literature, with special emphasis on multifocal lesions. Read More

    Oral melanoacanthoma and oral melanotic macule: a report of 8 cases, review of the literature, and immunohistochemical analysis.
    Med Oral Patol Oral Cir Bucal 2007 Sep 1;12(5):E374-9. Epub 2007 Sep 1.
    Departamento de Patología y Medicina Oral, Centro Clínico de Cabeza y Cuello, Guatemala.
    Oral melanoacanthoma (MA) is a rare, benign pigmented lesion, similar to cutaneous MA, characterized by hyperplasia of spinous keratinocytes and dendritic melanocytes. The pathogenesis of oral MA remains uncertain, although its clinical behavior is suggestive of a reactive origin. The most common intraoral sites are the buccal mucosa, lip, palate and gingiva. Read More

    Oral melanoacanthoma: a case report, a review of the literature, and a new treatment option.
    Ann Otol Rhinol Laryngol 2005 Sep;114(9):677-80
    Department of Otolaryngology-Head and Neck Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA.
    Objectives: Oral melanoacanthoma is a rare condition that presents as a pigmented, painful lesion, most commonly on the buccal mucosa. Argon plasma coagulation is a new treatment option for benign oral lesions and is hypothesized to be efficacious for this rare mucosal disorder.

    Methods: Treatment of a case and a review of the English-language literature were performed. Read More

    Oral melanoacanthosis (melanoachantoma): report of a case and review of the literature.
    Med Oral Patol Oral Cir Bucal 2005 Jan-Feb;10(1):11-2; 9-11
    Centro de Medicina Oral de Guatemala, Ciudad de Guatemala, Guatemala.
    Oral melanoacanthosis (MA) is a rare pigmented mucosal lesion that is considered the counterpart of cutaneous melanoacanthoma. Microscopically the superficial epithelium shows mild to moderate acanthosis, spongiosis and prominent dendritic melanin producing melanocytes, which are present throughout the spinous keratinocytes. Reported cases show predilection for black females and the most common locations in decreasing frequency are buccal mucosa, lip, palate and gingiva. Read More

    Relative frequency of solitary melanocytic lesions of the oral mucosa.
    J Oral Pathol Med 2004 Oct;33(9):550-7
    Department of Oral Pathology and Oral Medicine, School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel.
    Background: Solitary pigmented lesions of melanocytic origin are uncommon in the oral mucosa. These lesions include the oral and labial melanotic macule, oral melanocytic nevus, oral melanoacanthoma, oral melanoma and atypical melanocytic proliferation. The purpose of the study was twofold: to report a large series of solitary melanocytic lesions from one source, and to determine the relative frequency of these lesions. Read More

    Oral melanoacanthoma: a report of 10 cases, review of the literature, and immunohistochemical analysis for HMB-45 reactivity.
    Am J Dermatopathol 2003 Feb;25(1):12-5
    Department of Oral and Maxillofacial Pathology, Medicine and Surgery, Temple University School of Dentistry, Philadelphia, Pennsylvania 19140-5096, USA.
    Oral melanoacanthoma (MA) is rare reactive mucosal lesion that, like cutaneous MA, demonstrates hyperplasia of spinous keratinocytes and melanocytes. Unlike MA of the skin, oral MA is unrelated to seborrheic keratosis. This series adds 10 cases to the limited number of previous reports of oral MA. Read More

    Multiple intraoral melanoacanthomas: a case report with unusual findings.
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2002 Jul;94(1):54-6
    Department of Diagnostic Sciences, Division of Oral Medicine, New Jersey Dental School, University of Medicine & Dentistry of New Jersey, 110 Bergen Street-D885, Newark, NJ 07103, USA.
    Melanoacanthoma is a rare, benign, mucocutaneous pigmented lesion characterized by colonization of acanthotic epithelium by dendritic melanocytes.(1,2) The most common intraoral sites are the buccal(3,4) and masticatory mucosa subject to chronic irritation.(1,5) The pathogenesis of oral melanoacanthoma remains uncertain, although its clinical behavior is suggestive of a reactive cause. Read More

    Oral melanoma and other pigmented lesions of the oral cavity.
    J Am Acad Dermatol 1991 Apr;24(4):527-37
    Department of Dermatology, University of Michigan, Ann Arbor.
    This article presents a review of oral malignant melanoma and other oral cavity pigmented lesions. The dismal prognosis for patients with oral malignant melanoma is partly due to patients' delayed recognition of signs of early disease and delayed diagnosis by physicians. Pigmented macules and plaques in the oral cavity, representing the radial growth phase of tumors, often go unrecognized for months or years before tumor invasion. Read More

    Melanoacanthosis (melanoacanthoma) of the oral mucosa.
    J Dermatol Surg Oncol 1990 Mar;16(3):231-6
    Department of Oral Pathology, Indiana University School of Dentistry, Indianapolis.
    A pigmented lesion of the oral mucosa that bears histologic resemblance to the cutaneous melanoacanthoma is discussed. A study of 22 cases, including 4 in the current series, shows that the intraoral lesion occurs most commonly in adult black women on the buccal mucosa and lip. The lesion is known to regress. Read More

    Oral melanoacanthoma with prominent spongiotic intraepithelial vesicles.
    J Cutan Pathol 1989 Dec;16(6):365-9
    Department of Dermatology, Cleveland Clinic Foundation, Ohio.
    Oral melanoacanthoma is a rarely-reported, benign pigmented lesion of oral mucosa. Spongiosis was only recently mentioned as a light-microscopical finding occasionally seen in oral melanoacanthoma, and the formation of spongiotic intraepithelial vesicles to our knowledge has never been reported. The authors discuss a case of a 34-year-old, black woman who acutely developed extensive hyperpigmented oral lesions which on the biopsy showed both intraepithelial dendritic melanocytes and severe spongiosis forming intraepithelial vesicles. Read More

    Mucosal melanotic macule, reactive type: a simulation of melanoma.
    J Am Acad Dermatol 1988 Nov;19(5 Pt 1):786-91
    Department of Dermatology, College of Physicians and Surgeons, Columbia University, New York, NY 10032.
    Two patients with spontaneously resolving hyperpigmented patches of the oral mucosa are reported. Histologically, lesions in both cases showed large pigment-laden dendritic cells singly dispersed at all levels of the epidermis, which simulated in situ melanoma. The absence of such cells in the basal layer of the epidermis served to histologically distinguish these lesions from a biologically malignant melanocytic tumor. Read More

    Rapidly expanding pigmented lesion of the buccal mucosa.
    J Am Dent Assoc 1988 Oct;117(5):620-2
    Laboratory Department, Naval Hospital, San Diego 92134-5000.
    A case of oral melanoacanthoma was presented. The differential diagnosis of pigmented lesions of the oral mucous membrane includes a wide variety of categories of disease including local and systemic manifestations of hereditary and developmental conditions, reactive and inflammatory lesions, neoplasms, and metabolic diseases. For some of these lesions the histopathological pattern is diagnostic; for others, the tissue structure and organization are nonspecific and intelligent evaluation requires clinicopathological correlation. Read More

    Mucosal melanosis.
    Dermatol Clin 1988 Apr;6(2):283-93
    Medical University of South Carolina, Charleston.
    The labial melanotic macule has an increased number of dendritic melanocytes along the basal layer. Numerous counterparts of the labial melanotic macule occur on the other mucosal and cutaneous surfaces. Most melanoacanthomas of the lip show a similar number of melanocytes along the junctional zone. Read More

    Intraoral melanoacanthoma: a reactive melanocytic hyperplasia. Case report.
    J Periodontol 1988 Jan;59(1):53-5
    Department of Pathology, Baylor College of Dentistry, Dallas, TX.
    Melanoacanthoma was originally described as a benign skin tumor of keratinocytes and dendritic melanocytes. There is now evidence that the intraoral lesions are unlike those occurring on skin. This article documents the reactive and reversible nature of the oral condition in a patient with these lesions. Read More

    Melanotic macules and melanoacanthomas of the lip. A comparative study with census of the basal melanocyte population.
    Am J Dermatopathol 1987 Oct;9(5):438-44
    Department of Pathology, Milton S. Hershey Medical Center, Hershey, Pennsylvania.
    Fifteen labial melanotic macules and three melanoacanthomas of the lip were studied with particular regard to their distinguishing histopathological features including a quantitative study of the basal melanocyte population. Both of these entities show an increased population of melanocytes arranged as single units along the junctional zone. These conditions differ from each other primarily by the presence of intraepithelial melanocytes in melanoacanthoma. Read More

    Oral melanoacanthoma. Review of the literature and report of ten cases.
    Oral Surg Oral Med Oral Pathol 1983 Dec;56(6):622-8
    Melanoacanthoma is a simultaneous benign proliferation of two cell types--the keratinocyte and the melanocyte. It is a rare lesion; only twenty cases have been reported on skin and three cases intraorally. This article reports a series of ten cases of intraoral melanoacanthoma. Read More

    Intraoral melanoacanthoma.
    J Periodontol 1983 Feb;54(2):107-11
    Two cases of melanoacanthoma occurring on oral mucous membranes are presented. Melanoacanthoma is considered to be a benign mixed tumor of keratinoacytes admixed with pigment-laden dendritic melanocytes. All intraoral melanoacanthomas reported thus far have been pigmented lesions of the buccal mucosa and have occurred in young to middle-aged black females. Read More

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