56 results match your criteria Oral Melanoacanthoma

Update from the 5th Edition of the World Health Organization Classification of Head and Neck Tumors: Tumours of the Oral Cavity and Mobile Tongue.

Head Neck Pathol 2022 Mar 21;16(1):54-62. Epub 2022 Mar 21.

Department of Oral Pathology, Faculty of Dental Sciences, University of Peradeniya, Peradeniya, Sri Lanka.

The fifth chapter of the upcoming fifth edition of the 2022 World Health Organization Classification of Tumours of the Head and Neck titled Tumours of the oral cavity and mobile tongue, has had some modifications from the 2017 fourth edition. A new section "Non-neoplastic Lesions", introduces two new entries: necrotizing sialometaplasia and melanoacanthoma. The combined Oral potentially malignant disorders and Oral epithelial dysplasia section in the 2015 WHO has now been separated and submucous fibrosis and HPV-associated dysplasia are also discussed in separate sections. Read More

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Case Report of Conjunctival Melanoacanthoma.

Cornea 2021 Nov 2. Epub 2021 Nov 2.

Department of Ophthalmology, Dell Medical School, University of Texas, Austin, TX; Texas Oculoplastics Consultants (TOC) Eye & Face, Austin, TX; and Department of Dermatopathology and Ocular Pathology, Clinical Pathology Associates, Austin, TX.

Purpose: The purpose of this study was to describe a case of conjunctival melanoacanthoma, an exceedingly rare condition that has yet to be fully described in the literature.

Methods: Melanoacanthomas are most commonly seen on the skin or oral mucosa and are believed to result from local irritation or trauma. A 34-year-old Hispanic man presented with a painless, solitary, pigmented conjunctival lesion, in addition to bilateral pterygia suggesting chronic solar damage. Read More

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November 2021

Case Report: A rare presentation and diagnosis of gingival melanoacanthoma caused by teeth whitening strips: A Case Report.

F1000Res 2020 14;9:1452. Epub 2020 Dec 14.

Preventive Dental Science Department, College of Dentistry, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.

Oral melanoacanthoma is not common. It occurs mostly on the buccal mucosa. Since it happens suddenly and progresses rapidly, it clinically resembles melanoma. Read More

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Oral pigmented lesions: a retrospective analysis from Brazil.

Med Oral Patol Oral Cir Bucal 2021 May 1;26(3):e284-e291. Epub 2021 May 1.

Department of Oral Diagnosis and Pathology Federal University of Rio de Janeiro School of Dentistry Av. Carlos Chagas Filho 373, Prédio do CCS, Bloco K, 2° andar, Sala 56 Ilha da Cidade Universitária, Rio de Janeiro/RJ. 21.941-902

Background: Pigmented lesions are uncommon in the oral mucosa, and studies investigating the incidence and types of these lesions are desired to improve the diagnostic knowledge of clinicians. The aim of this study was to analyze the distribution of oral pigmented lesions in a Brazilian population.

Material And Methods: A retrospective descriptive cross-sectional study was performed. Read More

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A Unique Presentation of Gingival Melanoacanthoma: Case Report and Review of Literature.

Cureus 2020 Mar 18;12(3):e7315. Epub 2020 Mar 18.

Periodontics, Maulana Azad Institute of Dental Sciences, New Delhi, IND.

Melanoacanthoma is a benign, deeply pigmented condition of the oral mucosa characterized by the proliferation of melanocytes and keratinocytes. A 60-year-old male, with no history of systemic diseases or medical treatment, presented with an asymptomatic diffuse pigmentation involving the maxillary and mandibular gingiva. The histopathology of the anomalous pigmented area was analyzed and the dendritic melanocytes expressed positively for Masson-Fontana, S-100, and HMB-45. Read More

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Clinical and histopathological study of the oral multifocal melanoacanthoma: A case report.

J Clin Exp Dent 2019 Apr 1;11(4):e391-e394. Epub 2019 Apr 1.

MSc, PhD. Professor Department of Dentistry, State University of Paraíba, Campina Grande, Paraíba, Brazil.

Melanoacanthoma is a blackened mucocutaneous lesion, mainly affecting individuals with dark skin and exhibiting rapid development. Differential diagnosis includes nevus, amalgam tattoo and melanoma. This article reports a case of a 53-year-old white woman, who exhibited multiple blackened lesions on the gingiva and upper lip. Read More

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Black and Brown: Non-neoplastic Pigmentation of the Oral Mucosa.

Head Neck Pathol 2019 Mar 22;13(1):47-55. Epub 2019 Jan 22.

Louisiana State University, 1100 Florida Avenue, New Orleans, LA, 70119, USA.

Black and brown pigmentation of the oral mucosa can occur due to a multitude of non-neoplastic causes. Endogenous or exogenous pigments may be responsible for oral discoloration which can range from innocuous to life-threatening in nature. Physiologic, reactive, and idiopathic melanin production seen in smoker's melanosis, drug-related discolorations, melanotic macule, melanoacanthoma and systemic diseases are presented. Read More

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A rare case of oral melanoacanthoma.

J Oral Maxillofac Pathol 2018 Sep-Dec;22(3):410-412

Department of Oral Pathology and Microbiology, Sardar Patel Postgraduate Institute of Dental and Medical Sciences, Lucknow, Uttar Pradesh, India.

Oral melanoacanthoma is a rare, pigmented lesion which brings suspicion of a malignancy with its sudden appearance and rapid growth. It is characterized clinically as a brown-black lesion and histologically it shows acanthosis of the superficial epithelium and proliferation of dendritic melanocytes. Due to their unusual clinical pattern, biopsy is mandatory to rule out malignancy. Read More

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January 2019

Pigmented lesions of the oral mucosa: A cross-sectional study of 458 histopathological specimens.

Oral Dis 2018 Nov 10;24(8):1484-1491. Epub 2018 Jul 10.

Department of Oral Pathology and Surgery, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Objectives: To evaluate clinical, demographic, and histopathological characteristics of pigmented lesions of the oral mucosa.

Materials And Methods: A cross-sectional study was conducted over a 64-year period. Information was collected from medical charts, and all archived histopathological specimens with diagnoses of any pigmented lesion were retrieved. Read More

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November 2018

Gingival melanoacanthoma associated with pseudomelanocytic nests: Expanding the clinicopathological spectrum of a recently described oral lesion.

J Cutan Pathol 2018 May 12. Epub 2018 May 12.

Oral Pathology, Department of Stomatology, Public Oral Health, and Forensic Dentistry, Ribeirão Preto Dental School (FORP/USP), University of São Paulo - Avenida do Café, São Paulo, Brazil.

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Laugier-Hunziker Syndrome Presenting with Metachronous Melanoacanthomas.

Head Neck Pathol 2019 Jun 15;13(2):257-263. Epub 2018 Feb 15.

Department of Oral Diagnostic Sciences, School of Dental Medicine, University at Buffalo, The State University of New York, 355 Squire Hall, 3435 Main Street, Buffalo, NY, 14214-3008, USA.

Laugier-Hunziker syndrome (LHS, also termed idiopathic lenticular mucocutaneous hyperpigmentation) is an unusual condition characterized by progressive pigmentation of the mucous membranes. LHS displays a benign course and is not associated with malignancy. Here we present a case of LHS with a 7-year follow-up. Read More

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Oral melanoacanthoma of the palate: An unusual presentation of an uncommon entity.

JAAD Case Rep 2018 Mar 16;4(2):138-139. Epub 2018 Jan 16.

Department of Oral and Maxillofacial Surgery, Columbia University Medical Center, New York, New York.

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Oral melanoma and other pigmentations: when to biopsy?

J Eur Acad Dermatol Venereol 2018 Feb 14;32(2):209-214. Epub 2017 Sep 14.

Dermatology, Department of Experimental Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy.

Oral pigmentations (OPs) are often neglected, although a meticulous examination of the oral cavity is important not only in the diagnosis of oral melanoma, but also for the detection of important clinical findings that may indicate the presence of a systemic disease. OPs may be classified into two major groups on the basis of their clinical appearance: focal and diffuse pigmentations, even though this distinction may not appear so limpid in some cases. The former include amalgam tattoo, melanocytic nevi, melanoacanthoma and melanosis, while the latter include physiological/racial pigmentations, smoker's melanosis, drug-induced hyperpigmentations, postinflammatory hyperpigmentations and OPs associated with systemic diseases. Read More

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February 2018

Multifocal oral melanoacanthoma associated with Addison's disease and hyperthyroidism: a case report.

Arch Endocrinol Metab 2017 Jul-Aug;61(4):403-407. Epub 2017 Jun 26.

Divisão de Patologia Oral, Universidade Federal do Ceará (UFC), Fortaleza, CE, Brasil.

Oral melanoacanthoma is a mucocutaneous, pigmented, rare, benign, and probably reactive lesion. This paper reports for the first time in the literature a case of multifocal oral melanoacanthoma in a patient diagnosed with Addison's disease and concomitant Graves' disease with hyperthyroidism. The patient presented with oral pigmented lesions, which were hypothesized to be mucosal pigmentation associated with Addison's disease. Read More

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October 2017

Oral pigmentation in physiologic conditions, post-inflammatory affections and systemic diseases.

G Ital Dermatol Venereol 2018 Oct 19;153(5):666-671. Epub 2017 Apr 19.

Section of Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, University of Bologna, Bologna, Italy -

Melanocytes are found throughout the oral mucosa but usually go unnoticed because of their relatively low level of pigment production. When focally or generally active in pigment production or proliferation they may be responsible for several affections in the oral mucosae ranging from physiologic pigmentation, systemic diseases to malignant neoplasms. The diagnosis of oral pigmentations (OP) is usually challenging for the physician, but a careful examination of the oral cavity may reveal the first manifestation of underlying systemic diseases. Read More

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October 2018

Pathogenesis and clinicohistopathological caractheristics of melanoacanthoma: A systematic review.

J Clin Exp Dent 2016 Jul 1;8(3):e327-36. Epub 2016 Jul 1.

Professor of Oral Surgery. Co-Head of Master in Oral Surgery. University of Seville.

Introduction: The melanoacanthoma is a rare benign pigmented tumor, characterized by a fast radial growth and clinical behavior similar to melanoma. Color changes in oral mucosa and dermis are consequence of increased melanocyte activity as response to an irritant factor. There is a vast phenotypic variety. Read More

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Pigmented lesion with characteristics of malignancy: a case report.

Gen Dent 2013 Sep-Oct;61(6):e2-5

Pigmentations of the oral mucosa include a range of lesions or conditions that manifest as changes in the color of oral tissues; these changes may show melanocytic activity. A melanotic macule is a small, well-circumscribed melanocytic benign lesion. It can occur on the lips and intraorally and ranges in color from brown to black. Read More

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Immunohistochemical features of multifocal melanoacanthoma in the hard palate: a case report.

BMC Res Notes 2013 Jan 28;6:30. Epub 2013 Jan 28.

Department of Biosciences and Oral Diagnosis, São José dos Campos Dental School, São Paulo State University (UNESP), São José dos Campos, São Paulo, Brazil.

Background: Melanoacanthoma (MA) has been described in the oral mucosa as a solitary lesion or, occasionally, as multiple lesions. MA mainly affects dark skinned patients and grows rapidly, showing a plane or slightly raised appearance and a brown to black color. The differential diagnosis includes oral nevi, amalgam tattoos, and melanomas. Read More

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January 2013

Oral melanoacanthoma of a rare intraoral site: case report and review of literature.

Int J Clin Pediatr Dent 2013 Jan 26;6(1):40-3. Epub 2013 Apr 26.

Ex-Senior Lecturer, Department of Orthodontics and Dentofacial Orthopedics, Indira Gandhi Institute of Dental Sciences, Puducherry India.

Oral melanoacanthoma is rare pigmented mucosal lesion that presents most commonly on the buccal mucosa, characterized by sudden appearance and rapid radial growth, thus clinically mimicking malignant melanoma. It was originally described as a mixed tumor of melanocytes and keratinocytes, but appears to be a reactive process; formed in areas prone to trauma, and regressing after the removal of trauma or incomplete excision. The clinical appearance of oral melanoacanthoma is nondiagnostic, and biopsy is mandatory to rule out malignancy. Read More

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January 2013

Oral melanoacanthoma: A rare case of diffuse oral pigmentation.

J Oral Maxillofac Pathol 2012 Sep;16(3):441-3

Department of Oral and Maxillofacial Pathology, Vaidik Dental College and Research Centre, Daman, India.

The clinical presentation of diffuse pigmentation can be alarming to the patient as well as the clinician. A histopathologic examination of a pigmented lesion is necessary in most of the cases in the oral cavity. Oral melanoacanthoma is a very rare diffuse pigmentation with no specific treatment required. Read More

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September 2012

Oral pigmented lesions: Clinicopathologic features and review of the literature.

Med Oral Patol Oral Cir Bucal 2012 Nov 1;17(6):e919-24. Epub 2012 Nov 1.

Oral Pathology Division, Department of Oral Diagnosis, Piracicaba Dental School, State University of Campinas, Piracicaba, Brazil.

Diagnosis of pigmented lesions of the oral cavity and perioral tissues is challenging. Even though epidemiology may be of some help in orientating the clinician and even though some lesions may confidently be diagnosed on clinical grounds alone, the definitive diagnosis usually requires histopathologic evaluation. Oral pigmentation can be physiological or pathological, and exogenous or endogenous. Read More

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November 2012

Multifocal oral melanoacanthoma and melanotic macula in a patient after dental implant surgery.

J Am Dent Assoc 2011 Jul;142(7):817-24

Department of Oral Surgery and Implant Dentistry, School of Dentistry, University of Granada, Spain.

Background: Oral melanoacanthoma (OMA) is an uncommon, reactive, pigmented mucocutaneous lesion. It is a rapidly growing, well-circumscribed, small, brown-to-black, solitary or multifocal macule that is characterized histopathologically by proliferation of keratinocytes and pigment-laden dendritic melanocytes.

Case Description: At the end of a one-month healing period after dental implant surgery, a 63-year-old white woman had pigmented lesions at different oral mucosal sites (hard palate, buccal mucosa and left maxillary tuberosity) that showed macrophages exhibiting iron and melanin in multiple areas of the lamina propria. Read More

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Gingival melanoacanthoma: case report and discussion of its clinical relevance.

Quintessence Int 2011 Mar;42(3):253-8

Department of Oral Diagnostic Sciences, School of Dental Medicine, State University of New York at Buffalo, Buffalo, NY 14214, USA.

Oral melanoacanthoma is an uncommon reactive condition that appears as a solitary pigmented lesion and is most often found on the buccal mucosa. For it to appear in the gingiva is extremely rare--only 11 cases are reported in the literature. This article presents a case of gingival melanoacanthoma and reviews the previously published cases. Read More

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Multifocal pigmentation of the oral cavity. Oral melanoacanthoma.

J Am Dent Assoc 2011 Jan;142(1):53-6

Department of Oral Medicine, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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January 2011

Oral melanoacanthoma in an adolescent.

Pediatr Dermatol 2010 Jul-Aug;27(4):384-7

Department of Oncology and Diagnostic Sciences, University of Maryland Dental School, Baltimore, Maryland 21201-1586, USA.

The etiopathogenesis of oral pigmentation is diverse. One such process is the oral melanoacanthoma, a reactive, melanocytic lesion, infrequently found in the pediatric subpopulation. To extend the knowledge of this lesion, we provide a case of gingival melanoacanthoma in a 17-year-old male patient. Read More

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November 2010

Multifocal diffuse oral melanoacanthoma: a case report.

J Oral Sci 2009 Sep;51(3):463-6

Department of Oral Pathology, School of Dentistry, University of São Paulo, Brazil.

Oral melanoacanthoma (OMA) is a rare benign lesion characterized by colonization of acanthotic epithelium by dendritic melanocytes. Although its pathogenenesis remains uncertain, its clinical behavior and spontaneous remission suggest a non-neoplastic nature. Clinically, it may present as a solitary or multifocal lesion; however these two variants exhibit different features. Read More

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September 2009