35 results match your criteria Oral Leukoplakia Idiopathic

  • Page 1 of 1

Potentially Malignant Oral Disorders and Cancer Transformation.

Anticancer Res 2018 Jun;38(6):3223-3229

Department of Oral Medicine and Pathology, Institute of Odontology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

Cancer in the oral cavity is often preceded by precursor lesions. Nine oral mucosal disorders are known to have an increased risk of malignant transformation. The etiology varies from disorders caused by exogenous factors such as tobacco and autoimmune inflammation to idiopathic or inherited genetic aberrations. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21873/anticanres.12587DOI Listing
June 2018
4 Reads

Meta-analysis on clinicopathologic risk factors of leukoplakias undergoing malignant transformation.

J Oral Maxillofac Pathol 2016 Sep-Dec;20(3):354-361

Department of Oral and Maxillofacial Pathology, The Oxford Dental College, Bengaluru, Karnataka, India.

Context: Leukoplakia is classified under the term potentially malignant disorder. This term does not suggest the clinician or the patient about the severity of the disease to undergo a malignant transformation. Thus, there arises a need to identify the risk factors associated with malignant transformation (MT) to predict it at the earliest. Read More

View Article

Download full-text PDF

Source
http://www.jomfp.in/text.asp?2016/20/3/354/190900
Publisher Site
http://dx.doi.org/10.4103/0973-029X.190900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5051280PMC
October 2016
4 Reads

ORAL IDIOPATHIC HOMOGENEOUS LEUKOPLAKIA.

Authors:
Thorakkal Shamim

J Ayub Med Coll Abbottabad 2016 Jan-Mar;28(1):213

View Article

Download full-text PDF

Source
June 2016
8 Reads

Current strategies for prevention of oral manifestations of human immunodeficiency virus.

Authors:
Lauren L Patton

Oral Surg Oral Med Oral Pathol Oral Radiol 2016 Jan 9;121(1):29-38. Epub 2015 Sep 9.

Professor and Chair Department of Dental Ecology, CB 7450, School of Dentistry, University of North Carolina, Chapel Hill, NC, USA. Electronic address:

Objectives: Strategies to prevent new-onset and recurrent oral manifestations of human immunodeficiency virus (HIV), including fungal, viral, neoplastic, and idiopathic mucosal diseases and destructive periodontal conditions, are poorly understood.

Study Design: A structured review of the English language literature in PubMed through March 2015 was conducted to identify current prevention strategies for initial and recurrent oral manifestations of HIV.

Results: Pharmacologic approaches, including combination antiretroviral therapy or other targeted therapies for prevention of oropharyngeal candidiasis, orolabial herpes, oral hairy leukoplakia, oral Kaposi sarcoma, linear gingival erythema and necrotizing ulcerative periodontitis were found. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.oooo.2015.09.004DOI Listing
January 2016
3 Reads

Juvenile Idiopathic Inflammatory Myopathy in a Patient With Dyskeratosis Congenita Due to C16orf57 Mutation.

J Pediatr Hematol Oncol 2016 Mar;38(2):e75-7

Department of Pediatric Immunology, Uludag University Medical Faculty, Görükle, Bursa, Turkey.

Dyskeratosis congenita (DC) is a rare inherited disorder characterized by reticular skin pigmentation, oral cavity leukoplakia, and nail dystrophy. A variety of noncutaneous (dental, pulmonary, gastrointestinal, neurological, genitourinary, ophthalmic, and skeletal) abnormalities also have been reported. An 8-year-old boy with DC developed juvenile idiopathic inflammatory myopathy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MPH.0000000000000455DOI Listing
March 2016
5 Reads

The wide-ranging clinical implications of the short telomere syndromes.

Intern Med J 2016 Apr;46(4):393-403

Children's Medical Research Institute, The University of Sydney, Sydney, New South Wales, Australia.

There is an increasing number of inherited disorders in which excessive telomere shortening underlies the molecular defect, with dyskeratosis congenita (DC) being the archetypal short telomere syndrome. DC is classically described as a mucocutaneous triad of oral leukoplakia, nail dystrophy and abnormal skin pigmentation. However, excessive telomere shortening can affect almost any organ system, so the clinical manifestations are protean, including developmental delay, cerebellar hypoplasia, exudative retinopathy, aplastic anaemia, acute myeloid leukaemia, idiopathic pulmonary fibrosis, idiopathic hepatic cirrhosis, head and neck cancer and dental abnormalities, and may be multi-systemic. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/imj.12868DOI Listing
April 2016
1 Read

Idiopathic leukoplakia- report of a rare case and review.

J Clin Diagn Res 2015 Mar 1;9(3):ZD11-2. Epub 2015 Mar 1.

Professor, Department of Oral Medicine & Radiology, The Oxford Dental College, Hospital & Research Centre , Bommanahalli, Hosur Road, Bangalore, Karnataka, India .

Idiopathic leukoplakia is a rare potentially malignant lesion, usually found on the tongue with an increased risk of malignant transformation as compared to the tobacco associated form. The risk of malignant transformation increases with age. Diagnosis poses a challenge to the clinician as it is diagnosed by exclusion of other possible causes leading to hyperkeratosis. Read More

View Article

Download full-text PDF

Source
http://jcdr.net/article_fulltext.asp?issn=0973-709x&year
Publisher Site
http://dx.doi.org/10.7860/JCDR/2015/11197.5648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413161PMC
March 2015
6 Reads

Isolated lichen planus of lower lip: a case report.

Indian J Otolaryngol Head Neck Surg 2015 Mar 24;67(Suppl 1):151-3. Epub 2014 Aug 24.

Department of Pathology and Lab Medicine, All India Institute of Medical Sciences, Bhopal, India.

Lichen planus is an idiopathic inflammatory condition, which may involve mucosa of the oral cavity, gastrointestinal tract, larynx or the cutaneous surface either in isolation or in combinations. Mucosal lichen planus is more common than the cutaneous variant. Isolated lip involvement is very rare and should be differentiated from other similar leukoplakic lesions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12070-014-0768-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4298609PMC
March 2015
12 Reads

Oral leukoplakia in a South African sample: a clinicopathological study.

Oral Dis 2013 Sep 4;19(6):592-7. Epub 2012 Dec 4.

Department of Oral Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.

Objective: This study analysed differences in clinicopathological features of oral leukoplakia in different racial groups in the greater Johannesburg area of South Africa, with emphasis on the black population.

Material And Methods: The retrospective review included cases diagnosed clinically as oral leukoplakia and histologically as hyperkeratosis without dysplasia, hyperkeratosis with mild, moderate or severe dysplasia, and carcinoma in situ from 1990 to 2010. Age, gender, ethnicity, clinical appearance, site of lesion and tobacco smoking habit were recorded. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/odi.12040DOI Listing
September 2013
5 Reads

Idiopathic proliferative verrucous leukoplakia: report of a clinical rarity.

BMJ Case Rep 2012 Aug 2;2012. Epub 2012 Aug 2.

Department of Oral Medicine and Radiology, Rungta College of Dental Sciences, Bhilai, Chhattisgarh, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/bcr-2012-006194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542996PMC
August 2012
3 Reads

Rapid progression of an idiopathic leukoplakia to a proliferative verrucous leukoplakia lesion and then squamous cell carcinoma.

Quintessence Int 2012 Jul-Aug;43(7):583-5

Department of Stomatology, University of São Paulo, Brazil.

The article reports a case of oral proliferative verrucous leukoplakia (OPVL) in a 76-year-old woman, underscoring how an otherwise inconspicuous white plaque lesion can rapidly turn into a phase of verrucous carcinoma and subsequently squamous cell carcinoma. Read More

View Article

Download full-text PDF

Source
November 2012
8 Reads

Oral Leukoplakia as It Relates to HPV Infection: A Review.

Authors:
L Feller J Lemmer

Int J Dent 2012 28;2012:540561. Epub 2012 Feb 28.

Department of Periodontology and Oral Medicine, University of Limpopo, Medunsa Campus, Medunsa, South Africa.

Leukoplakia is the most common potentially malignant lesion of the oral cavity and can be categorised according to its clinical appearance as homogeneous or nonhomogenous. Tobacco and areca nut use, either alone or in combination are the most common risk factors for oral leukoplakia, but some oral leukoplakias are idiopathic. Some leukoplakias arise within fields of precancerized oral epithelium in which the keratinocytes may be at different stages of cytogenetic transformation. Read More

View Article

Download full-text PDF

Source
http://www.hindawi.com/journals/ijd/2012/540561/
Publisher Site
http://dx.doi.org/10.1155/2012/540561DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299253PMC
August 2012
5 Reads

Idiopathic linear leukoplakia of gingiva: A rare case report.

Authors:
N Sapna K L Vandana

J Indian Soc Periodontol 2010 Jul;14(3):198-200

Department of Periodontics, D.A.P.M R.V. Dental College, Bangalore, India.

White lesions of the oral cavity are not uncommon though majority of them are benign. This case report documents a rare case of idiopathic linear leukoplakia of gingiva with no apparent etiology. Initial examination revealed a non-scrapable linear white lesion on the marginal and papillary gingiva of upper right teeth region. Read More

View Article

Download full-text PDF

Source
http://www.jisponline.com/text.asp?2010/14/3/198/75918
Publisher Site
http://dx.doi.org/10.4103/0972-124X.75918DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100866PMC
July 2010
13 Reads

The genetics and clinical manifestations of telomere biology disorders.

Genet Med 2010 Dec;12(12):753-64

Division of Cancer Epidemiology and Genetics, Clinical Genetics Branch, National Cancer Institute, National Institutes of Health, Rockville, Maryland 20892, USA.

Telomere biology disorders are a complex set of illnesses defined by the presence of very short telomeres. Individuals with classic dyskeratosis congenita have the most severe phenotype, characterized by the triad of nail dystrophy, abnormal skin pigmentation, and oral leukoplakia. More significantly, these individuals are at very high risk of bone marrow failure, cancer, and pulmonary fibrosis. Read More

View Article

Download full-text PDF

Source
http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/GIM.0b013e3181f415b5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825100PMC
December 2010
3 Reads

Recent progress in dyskeratosis congenita.

Int J Hematol 2010 Oct 1;92(3):419-24. Epub 2010 Oct 1.

Department of Pediatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Shouwa-ku, Nagoya, 466-8550, Japan.

Dyskeratosis congenita (DC) is an inherited disease associated with nail dystrophy, abnormal skin pigmentation, oral leukoplakia, bone marrow failure and a predisposition to cancer. DC is a disease of defective telomere maintenance and patients with DC have very short telomeres. To date, mutations in six genes of telomerase and telomere components have been identified in patients with DC. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/content/pdf/10.1007/s12185-010-0695
Web Search
http://link.springer.com/10.1007/s12185-010-0695-5
Publisher Site
http://dx.doi.org/10.1007/s12185-010-0695-5DOI Listing
October 2010
2 Reads

Dental students' knowledge of human immunodeficiency virus.

Authors:
Y O Ajayi E O Ajayi

J Dent 2008 May 11;36(5):374-8. Epub 2008 Mar 11.

Department of Restorative Dentistry, School of Dental Sciences, College of Medicine, University of Lagos, P.M.B. 12003, Lagos, Nigeria.

Objective: This study evaluated final year dental students' knowledge of human immunodeficiency virus (HIV), lesions associated with HIV, potential transmission routes of HIV, and their perception of the teaching received on cross-infection precautions, virology, sterilization practice and procedure, barrier dentistry and recognition of blood-borne virus risk group.

Methodology: Structured questionnaires on knowledge of human immunodeficiency virus were filled by final year dental students of University of Lagos, Nigeria. A total of 35 out of 37 questionnaires were returned filled giving a response rate of 94. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jdent.2008.02.008DOI Listing
May 2008
5 Reads

Epidemiological and clinicopathological study of oral leukoplakia.

Indian J Dermatol Venereol Leprol 2005 May-Jun;71(3):161-5

Department of Dermatology and Venereology, S.C.B. Medical College, Cuttack, Orissa, India.

Background: Oral white lesions that cannot be clinically or pathologically characterized by any specific disease are referred to as leukoplakia. Such lesions are well known for their propensity for malignant transformation to the extent of 10-20%. Exfoliative cytology is a simple and useful screening tool for detection of malignant or dysplastic changes in such lesions. Read More

View Article

Download full-text PDF

Source
March 2006
9 Reads

Incidence rates for oral leukoplakia and lichen planus in a Japanese population.

J Oral Pathol Med 2005 Oct;34(9):532-9

Department of Oral and Maxillofacial Surgery II, School of Dentistry, Aichi-Gakuin University, Nagoya, Japan.

Background: Data on the incidence rates of potentially malignant diseases of the oral cavity in different populations is meagre. This is the first study to report on the age-specific incidence of oral leukoplakia and oral lichen planus from an industrialized country.

Methods: Annual screening for oral cancer and pre-cancer was undertaken in Municipal Health Centres in Tokoname city, Japan from 1995 to 1998. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1600-0714.2005.00349.xDOI Listing
October 2005
10 Reads

Expression of alpha-defensin-1 in chronic hyperplastic candidosis.

J Oral Pathol Med 2005 Jul;34(6):347-51

Department of Anatomy/Biomedicum, University of Helsinki, Helsinki, Finland.

Background: Chronic hyperplastic candidosis (CHC) represents a chronic opportunistic candida infection. We clarified the presence, localization and participation of alpha-defensin-1 in host response against chronic candidal stimulus.

Methods: Immunohistochemically stained CHC biopsies (n = 10) were compared to candida negative idiopathic leukoplakia (n = 10). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1600-0714.2005.00317.xDOI Listing
July 2005
6 Reads

Aggressive, multifocal oral verrucous leukoplakia: proliferative verrucous leukoplakia or not?

J Oral Pathol Med 2003 Aug;32(7):383-92

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, University of Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300 Kuala Lumpur, Malaysia.

Background: Some oral verrucal lesions may constitute parts of the clinicopathological spectrum of proliferative verrucous leukoplakia (PVL). Because of its idiopathic yet sinister nature, it is possible that PVL may exist in other populations. The aim of this study was to review the clinicopathological features of persistent, multifocal, oral verrucal lesions in Malaysian population. Read More

View Article

Download full-text PDF

Source
August 2003
7 Reads

Oral leukoplakia: a proposal for uniform reporting.

Oral Oncol 2002 Sep;38(6):521-6

Department of Oral & Maxillofacial Surgery/Pathology, Vrije Universiteit medical centre/ACTA, PO Box 7057, Amsterdam, The Netherlands.

Leukoplakia is the most common precancerous lesion of the oral mucosa. In order to promote uniform reporting of management results, including the event of malignant transformation, recommendations have been made for the various definitions and terminologies, including the application of a certainty factor with which the diagnosis of oral leukoplakia has been established. For reporting purposes there seems to be no rationale for distinguishing "tobacco-associated" leukoplakias from non-tobaccco-associated, so-called idiopathic leukoplakias. Read More

View Article

Download full-text PDF

Source
September 2002
3 Reads

Search for correlation between symptoms and signs of changes in the oral mucosa and presence of fungi.

Authors:
A J Kurnatowska

Mycoses 2001 Nov;44(9-10):379-82

Department of Conservative Dentistry, Medical University of Lodź, Poland.

The aim of the present study was to determine the relationship between the symptoms and signs of oral mucosal changes and the presence of fungi. The investigation comprised 235 subjects. Fungi were detected in the oral cavities of 196 of these subjects. Read More

View Article

Download full-text PDF

Source
November 2001
4 Reads

Laser management of oral leukoplakias: a follow-up study of 70 patients.

Laryngoscope 1999 Jun;109(6):949-53

University of California, Department of Stomatology, School of Dentistry, San Francisco, USA.

Objectives/hypothesis: To assess the efficacy of laser therapy for the management of premalignant oral lesions.

Study Design: The study group consisted of seventy consecutive laser-treated patients with oral leukoplakia. The microscopic diagnosis included idiopathic focal keratosis, dysplasias of all grades, and verrucous hyperplasia (proliferative verrucous leukoplakia). Read More

View Article

Download full-text PDF

Source
June 1999
1 Read

Diagnosis and treatment of common oral lesions found in the elderly.

Authors:
J E Fantasia

Dent Clin North Am 1997 Oct;41(4):877-90

Department of Dental Medicine, Long Island Jewish Medical Center, New Hyde Park, New York 11040, USA.

A wide variety of oral lesions are recognized in the geriatric patient. The most common lesions include neoplasia, immunologic based mucosal disease, hematological disorders, oral manifestation of systemic disease, and conditions characterized by oral or facial pain. Diagnostic and treatment considerations for leukoplakia, carcinoma, metastatic disease, candidiasis, herpes zoster, plasmacytoma, myeloma, lymphoma, several of the more common vesiculoulcerative mucosal diseases and idiopathic burning mouth syndrome are presented. Read More

View Article

Download full-text PDF

Source
October 1997
4 Reads

Prevalence of oral mucosal lesions in a Kenyan population with special reference to oral leukoplakia.

East Afr Med J 1995 Dec;72(12):778-82

Dental School, University of Nairobi, Kenya.

The prevalence of oral leukoplakia and related lesions in a Kenyan rural population was determined in a systematic house to house survey of individuals aged 15 years and above. Among the 803 individuals examined, the following prevalence of lesions was observed: leukoedema (26%), melanosis (12.7%), leukoplakia (10. Read More

View Article

Download full-text PDF

Source
http://studentsrepo.um.edu.my/3670/2/SECOND_PART._DR._RAJI_M
Web Search
December 1995
4 Reads

Early diagnosis and prevention of oral cancer and precancer: report of Symposium III.

Authors:

Adv Dent Res 1995 Jul;9(2):134-7

Oral precancer encompasses several conditions and lesions. Among those entities included in the concept are leukoplakia, erythroplakia, lichen planus, and submucous fibrosis. For prevention, knowledge about etiologic and pathogenetic factors is imperative. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/08959374950090021301DOI Listing
July 1995
4 Reads

Knowledge of the human immunodeficiency virus among final year dental students.

J Dent 1994 Aug;22(4):229-35

Department of Dental Surgery & Periodontology, University of Dundee, Scotland, UK.

A sound basis of knowledge about HIV infection and AIDS is essential to allow students to develop as dentists who undertake appropriate measures during clinical practice. In addition, it is also likely that possessing appropriate information may instil confidence in their own ability to diagnose and then manage patients infected by HIV. A questionnaire designed to test the knowledge of final year dental students in the UK was completed by 60. Read More

View Article

Download full-text PDF

Source
August 1994
3 Reads

Idiopathic leukoplakia lingualis.

Gen Dent 1993 Nov-Dec;41(6):547-9

Geriatric, Research, Education, and Clinical Center, Veterans Affairs Medical Center, 1601 SW Archer Road, Gainesville, FL 32608-1197, USA.

A 67-year-old man had a nonspecific leukoplakia of the tongue. It was of recent onset and had no readily apparent etiology. From the differential diagnosis of seven conditions, biopsy was consistent with a benign hyperkeratotic process. Read More

View Article

Download full-text PDF

Source
March 2015
1 Read

Prevalence of oral soft tissue lesions in out-patients at two Malaysian and Thai dental schools.

Community Dent Oral Epidemiol 1990 Apr;18(2):95-9

Department of Oral Surgery, Faculty of Odontology, Lund University, Malmö, Sweden.

At the Faculties of Dentistry in Chiang Mai, Thailand (CM), and Kuala Lumpur, Malaysia (KL), 234 and 233 consecutive out-patients of mean ages 33.8 and 31.0 yr, respectively, were examined for the presence of oral mucosal lesions. Read More

View Article

Download full-text PDF

Source

Oral leukoplakia, with emphasis on malignant transformation. A follow-up study of 46 patients.

J Craniomaxillofac Surg 1989 Apr;17(3):128-33

Dept. of Oral Surgery, Teaching Hospital, Free University/ACTA, Amsterdam, The Netherlands.

A review of oral leukoplakia, based on data from the literature and experience with 84 patients is presented. The leukoplakic lesions of 3 patients developed malignant transformation within an average period of 5 years. All three patients were elderly women with idiopathic leukoplakia, in two cases of the homogeneous and in one case of the non-homogeneous type. Read More

View Article

Download full-text PDF

Source
April 1989
1 Read

Bilateral white corrugated lesions on the lateral tongue surface.

J Am Dent Assoc 1988 Apr;116(4):544-6

Dental Service, VA Medical Center, San Francisco 94121.

A patient with bilateral hairy leukoplakia and candidiasis of the tongue was diagnosed and described. Lesions of the tongue that should be considered in the differential diagnosis include: idiopathic clinical leukoplakia, tobacco-induced leukoplakia, frictional keratosis, edema, lichen planus, galvanic lesions, geographic tongue, maceration, and chronic hyperplastic candidiasis. Hairy leukoplakia occurs predominantly on the tongue as in the patient described. Read More

View Article

Download full-text PDF

Source
April 1988
6 Reads

Occurrence of leukoplakia and some other oral white lesions among 20,333 adult Swedish people.

Authors:
T Axéll

Community Dent Oral Epidemiol 1987 Feb;15(1):46-51

Among 20,333 people aged 15 yr or above, the prevalences of oral white lesions were calculated based on a partly new classification. The total prevalences were: cheek and lip biting 5.1%, smoker's palate 1. Read More

View Article

Download full-text PDF

Source
February 1987
3 Reads

[Idiopathic leucokeratosis].

Riv Odontostomatol Implantoprotesi 1982 Jul-Aug(4):89, 91

View Article

Download full-text PDF

Source
March 1983
4 Reads

Effect on oral leukoplakia of reducing or ceasing tobacco smoking.

Authors:
B Roed-Petersen

Acta Derm Venereol 1982 ;62(2):164-7

Oral leukoplakia patients who were smokers were asked to give up their smoking habits. It was found that leukoplakias present in persons with smoking habits might be reversible, when the smoking habit was reduced or given up. Leukoplakias which were not reversible could possibly be of the same idiopathic type as leukoplakias in non-smokers. Read More

View Article

Download full-text PDF

Source
September 1982
1 Read
  • Page 1 of 1