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    Role of imaging in the diagnosis of parotid infantile hemangiomas.
    Int J Pediatr Otorhinolaryngol 2017 Nov 4;102:61-66. Epub 2017 Sep 4.
    Vascular Anomalies Center, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA; Division of Vascular and Interventional Radiology, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA. Electronic address:
    Objectives: To review the clinical presentation, imaging and follow-up of parotid infantile hemangiomas (IH).

    Methods: Over a 15-year period, all patients with a clinical diagnosis of parotid IH were evaluated. Imaging was available in 35. Read More

    Clinical and Radiological Evaluation of Periocular Infantile Hemangioma Treated With Oral Propranolol: A Case Series.
    Am J Ophthalmol 2017 Nov 15. Epub 2017 Nov 15.
    Department of Ophthalmology, Hospital das Clínicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, Brazil.
    Purpose: To evaluate the efficacy of propranolol (3 mg/kg/day) in the treatment of periocular infantile hemangioma (IH) based on clinical and radiological findings.

    Design: Prospective interventional case series.

    Methods: Study of previously untreated infants with IH conducted at the ophthalmology outpatient service of HC-FMUSP (Brazil). Read More

    A report on the clinical-pathological correlations of 788 gingival lesion.
    Med Oral Patol Oral Cir Bucal 2017 Nov 1;22(6):e686-e693. Epub 2017 Nov 1.
    Department of Surgical Sciences, University of Turin, CIR - Dental School, Oral Medicine Section, Via Nizza 230, 10126 Turin, Italy,
    Background: The diagnosis and treatment of a variety of non-plaque related gingival diseases have become an integrated aspect of everyday dentistry. The aim of this study was to analyse the relationship between clinical appearance and histopathological features of gingival lesions in a large Northern Italian population.

    Material And Methods: A retrospective study of 788 cases of gingival and alveolar mucosal biopsies was set up. Read More

    Intraosseous Hemangioma of the Frontal Bone. Report of a Case and Review of the Literature.
    J Oral Maxillofac Surg 2017 Sep 23. Epub 2017 Sep 23.
    Program Director, Associate Professor, and Chief of Oral and Maxillofacial Surgery, Harborview Medical Center, Seattle, WA. Electronic address:
    Intraosseous hemangiomas of the maxillofacial region are rare lesions that constitute less than 1% of all osseous tumors. A review of the literature on intraosseous hemangiomas of the skull and facial bones showed a limited number of publications, much of which were largely limited to case reports. This case report summarizes the workup and surgical treatment of a 39-year-old woman with an intraosseous hemangioma of the left frontal bone. Read More

    Combined Oral and Topical Beta Blockers for the Treatment of Early Proliferative Superficial Periocular Infantile Capillary Hemangioma.
    J Pediatr Ophthalmol Strabismus 2017 Oct 9:1-6. Epub 2017 Oct 9.
    Purpose: To evaluate the safety and efficacy of combined oral and topical beta blockers for the treatment of superficial periocular infantile hemangioma at the early proliferative stage.

    Methods: This was a randomized, controlled comparison trial involving 25 patients. Patients were randomly enrolled into two groups: the topical and systemic treatment and systemic treatment only groups. Read More

    A 24-Week Treatment of Pediatric Hemangioma with Oral Propranolol.
    Iran J Pharm Res 2017 ;16(2):811-816
    Cancer Research Center and Department of Pharmacology, Semnan University of Medical Sciences, Semnan, Iran.
    Hemangioma is a benign vascular tumor that shouldbe treated in problematic situations.Propranolol efficacy, target dose, range of age, duration of treatment and complications arenot conclusive for treatment of pediatric hemangioma. Our goal was to study efficacy and safety of propranolol for hemangioma treating in children. Read More

    Propranolol Treatment of Vascular Anomalies Other Than Infantile Hemangioma.
    J Craniofac Surg 2017 Nov;28(8):2001-2003
    Department of Plastic and Oral Surgery Children's Hospital Boston Harvard Medical School Boston, MA.
    Background: Oral propranolol has become first-line intervention for problematic infantile hemangioma (IH) that is not amenable to topical or intralesional therapies. Consensus data supporting its efficacy for other vascular anomalies does not exist. The purpose of this study was to determine the frequency and causes of propranolol use for vascular lesions other than IH. Read More

    Cavernous lymphangioma of the tongue in an adult: a case report.
    J Istanb Univ Fac Dent 2017 3;51(2):49-53. Epub 2017 Apr 3.
    Department of Oral and Maxillofacial Surgery Faculty of Dentistry Istanbul University Turkey.
    Lymphangioma is a benign hamartomatous lesion caused by congenital malformation of the lymphatic system. This benign tumor is detected most commonly at birth or in early childhood but rarely in adults. On clinical examination, most lymphangiomas contain clear lymph fluid, but some may present as transparent vesicles containing red blood cells due to hemorrhage. Read More

    Inhibition of hemangioma growth using polymer-lipid hybrid nanoparticles for delivery of rapamycin.
    Biomed Pharmacother 2017 Nov 10;95:875-884. Epub 2017 Sep 10.
    Department of Vascular Surgery, Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1277 Jiefangdadao Road, Wuhan 430022, Hubei, China. Electronic address:
    Although infantile hemangiomas is benign, its rapid growth may induce serious complications. However, only one drug Hemangeol™ has been approved by US Food and Drug Administration (FDA) to treat infantile hemangiomas. Thus it is necessary to develop novel alternative drugs to treat infantile hemangiomas. Read More

    Intramuscular hemangioma in buccal cheek: a case report.
    J Korean Assoc Oral Maxillofac Surg 2017 Aug 24;43(4):262-266. Epub 2017 Aug 24.
    Department of Oral and Maxillofacial Surgery, College of Dentistry, Dankook University, Cheonan, Korea.
    Hemangioma is the most common benign tumor of a vascular origin, and is characterized by the abnormal proliferation of blood vessels. Intramuscular hemangioma (IMH) usually involves the skeletal muscles of the trunk or limbs, but rarely occurs in the head and neck region. This case report presents a patient with IMH showing multiple phleboliths in the buccal cheek. Read More

    Survivin: A novel marker and potential therapeutic target for human angiosarcoma.
    Cancer Sci 2017 Nov 15;108(11):2295-2305. Epub 2017 Sep 15.
    Division of Cancer Biology, National Cancer Center Research Institute, Tokyo, Japan.
    Human angiosarcoma is a rare malignant vascular tumor associated with extremely poor clinical outcome and generally arising in skin of the head and neck region. However, little is known about the molecular pathogeneses and useful immunohistochemical markers of angiosarcoma. To investigate the mechanisms of angiosarcoma progression, we collected 85 cases of human angiosarcoma specimens with clinical records and analyzed ISO-HAS-B patient-derived angiosarcoma cells. Read More

    Prevalence and pattern of lobular capillary hemangioma in Eastern Madhya Pradesh, India: A clinicopathological analysis.
    Indian J Dent Res 2017 Jul-Aug;28(4):424-428
    Department of Oral and Maxillofacial Surgery, People's College of Dental Sciences and Research Centre, Bhopal, Madhya Pradesh, India.
    Background: Lobular capillary hemangioma is a common benign vascular tumor seen in the oral cavity. It occurs in response to various stimuli such as low-grade local irritation, traumatic insult, and hormonal factors or as a response to a wide variety of drugs.

    Materials And Methods: All patients presenting to the Department of Dentistry, Shyam Shah Medical College, Rewa, Madhya Pradesh during July 2014 to June 2016, who were diagnosed by histopathologic confirmation as oral lobular capillary hemangioma (OLCH), were evaluated for the area involved, clinicopathologic presentation, demographic features, and treatment. Read More

    Hepatic Adenoma - A Case Report.
    S D Med 2017 Mar;70(3):105-107
    Department of Surgery, University of South Dakota Sanford School of Medicine.
    Although liver lesions in the young population are relatively rare, clinicians can benefit from being familiar with a subset of common benign liver lesions which include hepatic adenoma, hepatic hemangioma, and focal nodular hyperplasia. This a case report of a 25-year-old Jehovah's Witness female on chronic oral contraception for polycystic ovarian syndrome who presented with progressive right upper quadrant abdominal pain. Ultrasound and MRI findings were consistent with hepatic adenoma. Read More

    Study of Cognitive Function in Children Treated with Propranolol for Infantile Hemangioma.
    Pediatr Dermatol 2017 Sep 14;34(5):554-558. Epub 2017 Aug 14.
    Department of Dermatology, Hospital del Niño Jesús, Madrid, Spain.
    Background: Oral propranolol is considered the first choice for the treatment of infantile hemangiomas (IHs). There is a concern that administering propranolol in newborns and infants could induce adverse effects in learning and memory processes in the long term. The purpose of this study was to assess cognitive and memory functions in children who had been treated with propranolol for IH during their infancy. Read More

    Simple Preparation of Timolol 0.5% Gel from Eye Drop Solution for Superficial Infantile Hemangiomas.
    Int J Pharm Compd 2017 Jul-Aug;21(4):282-289
    National Skin Centre Pte. Ltd., Singapore.
    The discovery of beta-adrenergic blocker effects on infantile hemangiomas has affected the choice of treatment in recent years. Oral propranolol is effective in treating infantile hemangiomas, but the risk of systemic side effects remains a concern. Data from literature review reported positive clinical outcomes with no major adverse effects observed in children using topical beta-blocker such as timolol maleate. Read More

    Topical Application of 0.5% Timolol Maleate Hydrogel for the Treatment of Superficial Infantile Hemangioma.
    Front Oncol 2017 27;7:137. Epub 2017 Jun 27.
    Department of Interventional Therapy, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
    The therapeutic options for infantile hemangiomas (IHs) have been greatly altered since the introduction of oral propranolol for successful treatments of IHs. Recently, there is an increase in the application of topical timolol maleate for treating superficial IHs. In the present study, we developed a new formulation of timolol maleate 0. Read More

    Variability of Delivery of Timolol for the Treatment of Infantile Hemangiomas.
    Pediatr Dermatol 2017 Jul 29;34(4):458-460. Epub 2017 Jun 29.
    Division of Pediatric Dermatology, Children's Hospital of Wisconsin, Milwaukee, Wisconsin.
    Background/objectives: Topical timolol maleate solution or gel-forming solution is used alone or in conjunction with oral propranolol for the treatment of infantile hemangiomas. The consistency of the amount of timolol dispensed has never been evaluated. We evaluated the variability of drug delivery between different brands and formulations of timolol solution and gel-forming solution. Read More

    Epithelioid hemangioendotheliomas of the liver and lung in children and adolescents.
    Pediatr Blood Cancer 2017 Dec 9;64(12). Epub 2017 Jun 9.
    German Cancer Consortium (DKTK), Partner site Freiburg, Freiburg, Germany.
    Epithelioid hemangioendothelioma (EHE) is a rare, vascular sarcoma. Visceral forms arise in the liver/ lungs. We review the clinical and molecular phenotype of pediatric visceral EHE based on the case of a 9-year-old male child with EHE of the liver/lungs. Read More

    Oral foregut duplication cysts: A rare and fascinating congenital lesion. Case report and review of the literature.
    Am J Otolaryngol 2017 Nov - Dec;38(6):724-725. Epub 2016 Nov 23.
    Department of Pathology, Louisiana State University Health Science Center, Shreveport, LA 71130, USA.
    Oral foregut duplication cysts are extremely rare lesions with approximately 57 cases reported. They are congenital cysts, located in the anterior or ventral tongue, and occur predominantly in males. They are lined by one or more types of epithelia which is limited to gastric, intestinal or respiratory epithelium. Read More

    Sildenafil suppresses the proliferation and enhances the apoptosis of hemangioma endothelial cells.
    Exp Ther Med 2017 Jun 5;13(6):2645-2650. Epub 2017 Apr 5.
    Department of Oral and Maxillofacial Surgery, Qilu Hospital, Shandong University, Jinan, Shandong 250012, P.R. China.
    Treatment of infantile hemangiomas (IH) with propranolol was first reported in 2008. Regressions of lymphatic malformations combined with pulmonary hypertension was first reported in 2012 after three children received treatment with oral sildenafil, which serves as an antagonist of phosphodiesterase isoform-5 (PDE-5). A marked expression of endothelial cells in the cytoplasm of IH tissues was obtained in our previous study. Read More

    Use of Topical Corticosteroids in Dermatology: An Evidence-based Approach.
    Indian J Dermatol 2017 May-Jun;62(3):237-250
    Department of Dermatology, KPC Medical College and Hospital, Kolkata, West Bengal, India.
    Topical corticosteroids (TCs) are the pillars of dermatotherapeutics. These drugs are the "magic molecules," provided they are used judiciously and appropriately, following a rational prescription. On exhaustive literature search in multiple databases, we found a significant evidence favoring the use of TCs in atopic eczema, localized vitiligo, psoriasis, chronic hand eczema, and localized bullous pemphigoid. Read More

    Unusual neoplasm on the hard palate of a child: a case report.
    J Med Case Rep 2017 Jun 2;11(1):149. Epub 2017 Jun 2.
    Department of Pediatric Surgery, Kasturba Medical College, Manipal University, Manipal, 576104, Karnataka, India.
    Background: Myoepitheliomas account for less than 1% of salivary gland tumors. They mostly affect the parotid glands of adults during the third to fifth decades.

    Case Presentation: A 10-year-old Indian boy reported a small swelling in the roof of his mouth of 10 days' duration. Read More

    Consequences of Facial Hemangioma with Regard to Dental Treatment.
    Contemp Clin Dent 2017 Jan-Mar;8(1):185-187
    Department of Pediatric Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, São Paulo, Brazil.
    Hemangioma is a benign vascular tumor that affects 3%-10% of the population and usually does not require specific treatment due to spontaneous regression. The purpose of this paper is to present a case report of a child having been born prematurely and diagnosed with hemangioma in the head and neck, emphasizing the dentofacial changes and treatment used to provide care. Severe fibrous scars were found in the perioral region and below the ear that limited the patient's ability to open her mouth. Read More

    An update of 77 cases diagnosed as oral hemangiomas based on GLUT-1 positivity.
    Exp Mol Pathol 2017 Aug 22;103(1):9-13. Epub 2017 May 22.
    Postgraduate Program, Oral Pathology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
    Objectives: To evaluate cases diagnosed as "oral hemangiomas" based on the immunohistochemical expression of human glucose transporter protein (GLUT-1) and on histopathological features, and to investigate whether the classification proposed by the ISSVA was used correctly to classify these lesions.

    Material And Methods: All cases stored in the archives of an Oral Pathology Service and diagnosed as "oral hemangiomas" were reviewed. Seventy-seven cases were analyzed regarding the expression of GLUT-1. Read More

    Interdisciplinary Management of Head and Neck Vascular Anomalies: Clinical Presentation, Diagnostic Findings and Minimalinvasive Therapies.
    Eur J Radiol Open 2017 14;4:63-68. Epub 2017 May 14.
    Department of Otorhinolaryngology and Head and Neck Surgery, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
    Objectives: Vascular anomalies are included in the 30 000 rare diseases worldwide affecting less than 5/10 000 people. Depending on their morphology and biological properties, they can cause varied disorders with organ involvement. Almost 60% of vascular anomalies have a predilection for the head and neck region in children. Read More

    Management of a Life Threatening Bleeding Following Extraction of Deciduous Second Molar Related to a Capillary Haemangioma.
    Craniomaxillofac Trauma Reconstr 2017 Jun 16;10(2):166-170. Epub 2017 Mar 16.
    Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ain Shams University, Cairo, Egypt.
    Various forms of vascular lesion affect the head and neck region. The head and neck vascular lesions are classified into neoplasms and malformations. Neoplasm presents either as hemangioma or lymphangioma; neoplasm usually presents in young age compared with vascular malformation. Read More

    Propranolol therapy for infantile hemangioma: our experience.
    Drug Des Devel Ther 2017 8;11:1401-1408. Epub 2017 May 8.
    Department of Oral-Maxillary Head and Neck, Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai.
    Objective: Hemangiomas are the most common benign vascular tumors of infancy. Although most infantile hemangiomas (IHs) have the ability to involute spontaneously after initial proliferation and resolve without consequence, intervention is required in a subset of IHs, which develop complications resulting in ulceration, bleeding, or aesthetic deformity. The primary treatment for this subset of IHs is pharmacological intervention, and propranolol has become the new first-line treatment for complicated hemangiomas. Read More

    Modern Management of Nasal Hemangiomas.
    JAMA Facial Plast Surg 2017 Jul;19(4):327-332
    Hemangioma and Malformation Treatment Center, Charleston, South Carolina.
    Importance: Current treatment approaches for infantile hemangiomas of the nose include observation, pharmacologic agents, surgery, and/or laser therapy. Because of the known functional, social, and cosmetic effect of nasal deformities, obtaining the best possible result is critical. Optimal timing, type, duration, and extent of therapy remain unclear. Read More

    Metastasis of a Renal Collecting Duct Adenocarcinoma to the Oral Cavity After Tooth Extraction.
    J Craniofac Surg 2017 Jun;28(4):e398-e399
    *Department of Pathology, Faculty of Medicine †Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Gaziantep University, Gaziantep ‡Department of Pathology, Faculty of Medicine, TOBB Economics and Technology, Ankara, Turkey.
    Metastatic tumors rarely occur in the oral cavity. The most common of the oral metastases are lung cancers in males, and breast and genital cancers in females. The most common primary tumor metastasis to the oral cavity is from the lung, kidney, liver, prostate, and colorectal cancers. Read More

    Intramuscular hemangiomas on the masseter muscle and orbicularis oris muscle: a report of two cases.
    J Korean Assoc Oral Maxillofac Surg 2017 Apr 25;43(2):125-133. Epub 2017 Apr 25.
    Department of Pathology, Inha University School of Medicine, Incheon, Korea.
    Intramuscular hemangioma (IMH) is a rare vascular disease involving skeletal muscle, comprising only 0.8% of hemangiomas. About 10% to 15% of IMHs occur in the head and neck region, mostly involving the masseter muscle. Read More

    Efficacy and safety of oral propranolol for infantile hemangioma in Japan.
    Pediatr Int 2017 Aug 30;59(8):869-877. Epub 2017 Jun 30.
    Maruho, Kyoto, Japan.
    Background: There have been few reports on the efficacy and safety of oral propranolol at 3 mg/kg/day for infantile hemangioma (IH) in Japanese patients.

    Methods: A multicenter, open-label phase III study was conducted to evaluate the efficacy and safety of oral propranolol solution in Japanese infants aged 35-150 days with proliferating IH. Thirty-two patients were enrolled in the study, received propranolol solution for 24 weeks at 3 mg/kg/day, and completed the study. Read More

    A case of 55-year-old man with first-ever generalized seizure diagnosed with Sturge-Weber syndrome type III by characteristic MRI findings.
    Rinsho Shinkeigaku 2017 05 27;57(5):214-219. Epub 2017 Apr 27.
    Department of Neurology, Mie University Graduate School of Medicine.
    A 55-year-old man with no mental retardation had presented a history of frequent transient clumsiness of his right upper and lower extremities for about 20 years. He was admitted to a general hospital with weakness of right side of the body, and first-ever generalized seizure attack occurred the next day. Brain CT showed calcification in the left cerebral cortices. Read More

    Association of ATF4 Expression With Tissue Hypoxia and M2 Macrophage Infiltration in Infantile Hemangioma.
    J Histochem Cytochem 2017 05 1;65(5):285-294. Epub 2017 Feb 1.
    The State Key Laboratory Breeding Base of Basic Science of Stomatology and Key Laboratory of Oral Biomedicine Ministry of Education (H-FX, J-YZ, J-NW, J-GR, YC, F-QW, WZ, GC, Y-FZ, J-HZ), School and Hospital of Stomatology, Wuhan University, Wuhan, China.
    Accumulating studies have revealed the hypoxic condition and its crucial role in the distinctive progression of infantile hemangioma (IH), the most common benign tumor in infancy. Activating transcription factor 4 (ATF4), an important gene mediating cellular adaptation to various stress signals, could confer a survival advantage for tumor cells under hypoxia and regulate tumor progression. However, the potential role of ATF4 in IH was still unknown. Read More

    Safety and effectiveness of oral propranolol for infantile hemangiomas started before 5 weeks and after 5 months of age: an Italian multicenter experience.
    Ital J Pediatr 2017 Apr 19;43(1):40. Epub 2017 Apr 19.
    Angioma Center, Cardiovascular Department, Gaslini Children's Research Institute, Genoa, Italy.
    Background: Despite not being licensed for the treatment of infantile hemangiomas (IH) in infants younger than 5 weeks or older than 5 months, propranolol is often used in these age groups to prevent or to treat potentially severe complications. The objective of the present study was to review the experience of 8 Italian pediatric and dermatologic centers regarding propranolol treatment for IH started before 5 weeks or after 5 months of age.

    Methods: We retrospectively reviewed the records of patients followed up for IH, on propranolol treatment started before 5 weeks or after 5 months of age, and collected information on sociodemographic data, treatment indications, IH involution, IH relapse, and treatment side effects. Read More

    One-Stage Supramaximal Full-Thickness Wedge Resection of Vascular Lip Anomalies.
    J Oral Maxillofac Surg 2017 Nov 22;75(11):2449-2455. Epub 2017 Mar 22.
    Staff, Vascular Birthmark Institute of New York, Department of Otolaryngology, Lenox Hill and Manhattan Eye, Ear, and Throat Hospitals, New York, NY; Assistant Clinical Professor, Department of Ophthalmology, Harvard Medical School, Boston, MA. Electronic address:
    Purpose: Vascular lip anomalies include infantile hemangiomas, venous malformations, and arteriovenous malformations. Surgical management can be complicated by alterations in horizontal length, vertical height, and lip thickness from the underlying pathology. Additional reconstructive challenges include preservation of oral continence, vermillion definition, and the sublabial sulcus. Read More

    Nasal glial heterotopia or congenital hemangioma? A case report.
    J Stomatol Oral Maxillofac Surg 2017 Oct 5;118(5):298-301. Epub 2017 Apr 5.
    Grenoble University Hospital, Department of Maxillo-facial Surgery, Avenue Maquis du Grésivaudan, 38700 La Tronche, France.
    Nasal glial heterotopia (NGH) is a rare benign tumor of the median line. We describe the case of a child presenting a lateral nasal mass. The characteristics of the prenatal ultrasound and the postnatal clinical examination argued in favor of a congenital hemangioma (CH). Read More

    Treatment of vascular lesions located in the lip and in the oral cavity with Nd:YAG laser.
    J Cosmet Laser Ther 2017 Oct 7;19(5):256-258. Epub 2017 Apr 7.
    a Hospital Federal da Lagoa , Rio de Janeiro , Brazil.
    Vascular lesions such as hemangiomas can be found in the oral cavity. Some therapeutic modalities can be used in the treatment of these lesions and Nd:YAG 1064 nm long pulse laser shows good results with easy application, fewer complications and satisfactory results. This study describes the technique and outcome of a case of hemangioma located on the tongue treated with Nd:YAG laser. Read More

    Analysis of factors affecting the therapeutic effect of propranolol for infantile haemangioma of the head and neck.
    Sci Rep 2017 Mar 23;7(1):342. Epub 2017 Mar 23.
    Department of Oral and Maxillofacial Surgery, Qilu Hospital, and Institute of Stomatology, Shandong University, Jinan, 250012, China.
    Infantile haemangiomas (IHs) are the most common congenital vascular tumours of infancy. Propranolol has been demonstrated to be effective for IHs; however, the factors affecting its therapeutic effect remain unknown. We enrolled 169 infants with IHs of the head and neck region treated with oral propranolol at a dose of 2. Read More

    Psoriasiform Diaper Rash Possibly Induced by Oral Propranolol in an 18-Month-Old Girl with Infantile Hemangioma.
    Case Rep Dermatol 2016 Sep-Dec;8(3):369-373. Epub 2016 Dec 22.
    Department of Dermatology, Centre Hospitalier de Saint-Brieuc, Saint-Brieuc, France.
    Propranolol, a nonselective blocker of β-adrenergic receptors, has become the first-line treatment for complicated infantile hemangiomas. Therefore, its use in the pediatric population has expanded in recent years. In adults, β-blockers have been reported to be the most common causative agents for drug-induced psoriasis. Read More

    Infantile Hemangioma of the Posterior Fossa in a Newborn: Early Management and Long-Term Follow-up.
    Neuropediatrics 2017 Oct 16;48(5):378-381. Epub 2017 Mar 16.
    Unité de Neurologie Pédiatrique, Hôpital des Enfants, CHU Purpan, Toulouse, France.
    A 21-day-old male infant was admitted with signs of intracranial hypertension. Brain magnetic resonance imaging (MRI) revealed a voluminous mass in the posterior fossa with an intense peripheral enhancement on T1 images with gadolinium. The child was treated secondarily by surgical decompression of the posterior fossa and the lesion was biopsied. Read More

    [A Rare Case of Cerebellar Hemangioblastoma Causing Taste Disorder].
    No Shinkei Geka 2017 Mar;45(3):219-224
    Department of Neurosurgery, Faculty of Medicine, Saga University.
    Taste(gustation)is one of the five senses, and comprises the types: sweet, bitter, salty, sour, and umami. Taste disorders, such as dysgeusia and parageusia, are classified into 2 types: those with peripheral origin and those with central origin. The peripheral origin-type taste disorder is caused by zinc deficiency, mouth dryness, a side effect of radiotherapy or complication of systemic diseases such as, diabetes, hepatopathy, and nephropathy. Read More

    [Chinese expert consensus on the use of topical timolol maleate treatment of infantile hemangiomas].
    Shanghai Kou Qiang Yi Xue 2016 Dec;25(6):744-747
    Department of Oral and Maxillofacial Surgery, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine. Shanghai 200011, China.
    Non-selective β-blocker propranolol has been proved by FDA as the first-line agent for infantile hemangioma (IH) with dramatic response. To reduce the side effects caused by systemic administration of propranolol, timolol maleate treatment has been increasingly used as an alternative to systemic β-blockers and watchful waiting for many IH patients in recent years. However, the appropriate indications, drug dosage, dosing regimen, time for initiation, optimal duration, monitoring for side effects still remains controversial. Read More

    Consensus statement for the treatment of infantile haemangiomas with propranolol.
    Australas J Dermatol 2017 May 1;58(2):155-159. Epub 2017 Mar 1.
    Royal Children's Hospital, Melbourne, Victoria, Australia.
    Although most infantile haemangiomas do not require treatment due to a natural history of spontaneous involution, some require early intervention. The Australasian Vascular Anomalies Network and the Australasian Paediatric Dermatology Network have developed a consensus statement for the treatment of infantile haemangiomas with oral propranolol. Infants with haemangiomas that are life threatening, at risk of ulceration, or at risk of causing a significant functional impairment, psychological impact or physical deformity should be treated early with oral propranolol. Read More

    When to stop propranolol for infantile hemangioma.
    Sci Rep 2017 Feb 22;7:43292. Epub 2017 Feb 22.
    From the Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
    There is no definitive conclusion regarding the optimal timing for terminating propranolol treatment for infantile hemangioma (IH). A total of 149 patients who underwent detailed color Doppler ultrasound examination were included in this study. The characteristics and propranolol treatment of all patients were summarized and analyzed. Read More

    Oral mucosal lesions in a Chilean elderly population: A retrospective study with a systematic review from thirteen countries.
    J Clin Exp Dent 2017 Feb 1;9(2):e276-e283. Epub 2017 Feb 1.
    Gerontology Program, Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
    Background: The oral examination is an essential part of the multidisciplinary medical care in elderly people. Oral mucosal lesions and normal variations of oral anatomy (OMLs) are very common in this people, but few studies have examined the frequency and prevalence of these conditions worldwide and less in Chile. The aim of this research was to evaluate the frequency of OMLs in a Chilean elderly population. Read More

    Zygomatic Intraosseous Hemangioma: Case Report and Literature Review.
    Craniomaxillofac Trauma Reconstr 2017 Mar 4;10(1):1-10. Epub 2016 Nov 4.
    Division of Plastic, Reconstructive, Maxillofacial and Oral Surgery, Department of Surgery, Duke University Medical Center, Durham, North Carolina.
    Intraosseous hemangiomas are uncommon intrabony lesions, representing approximately 0.5 to 1% of all intraosseous tumors. Their description varies from "benign vasoformative neoplasms" to true hamartomatous proliferations of endothelial cells forming a vascular network with intermixed fibrous connective tissue stroma. Read More

    Sinonasal Hemangioma: Diagnosis, Treatment, and Follow-Up of 37 Patients at a Single Center.
    J Oral Maxillofac Surg 2017 Aug 5;75(8):1775-1783. Epub 2017 Jan 5.
    Professor, Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Chonbuk National University, Jeonju, Korea; and Research Institute of Clinical Medicine of Chonbuk National University and Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea. Electronic address:
    Purpose: Hemangioma is a common benign vascular lesion of the head and neck region. It rarely involves the mucous membranes of the nasal cavity and paranasal sinuses. It should be added to the differential diagnosis of nasal cavity masses when the presenting symptoms are epistaxis or nasal obstruction. Read More

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