2,370 results match your criteria Oral Hemangiomas


Atenolol as an alternative to propranolol for the management of sleep disturbances in the treatment of infantile hemangiomas.

Pediatr Dermatol 2019 Apr 15. Epub 2019 Apr 15.

Section of Dermatology, Division of General Pediatrics, Department of Pediatrics and Dermatology, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

Infantile hemangiomas are the most common tumors of infancy and are often managed with oral beta-blockers to address or prevent associated complications. However, treatment with propranolol can occasionally be associated with sleep disturbances, which in some cases are severe enough to warrant discontinuation or replacement with another agent. We herein report four cases in which treatment with propranolol resulted in significant sleep disturbances prompting substitution with atenolol, which in some cases resolved these issues. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pde.13839DOI Listing
April 2019
1 Read

Topical timolol as adjunct therapy to shorten oral propranolol therapy for infantile hemangiomas.

Pediatr Dermatol 2019 Apr 9. Epub 2019 Apr 9.

Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Background/objectives: First-line therapy for infantile hemangiomas (IH) is oral propranolol, a systemic beta-blocker with the risk of rare but serious adverse effects. Topical timolol presents an attractive off-label alternative with good tolerability, but sequential therapy with propranolol followed by timolol is not well studied. Here, we report effects of topical timolol preceding or following oral propranolol as adjunct therapy for IH. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pde.13816DOI Listing
April 2019
1 Read

Successful treatment of an exudative choroidal hemangioma with oral propranolol in a 10-year-old boy.

J AAPOS 2019 Apr 5. Epub 2019 Apr 5.

Department of Ophthalmology and Visual Sciences, Washington University in St. Louis, St. Louis, Missouri. Electronic address:

A 10-year-old boy was referred for a circumscribed choroidal hemangioma with underlying exudative detachment of the left eye. To avoid general anesthetics required for laser-based therapy in a child, we began a trial of oral propranolol. The patient's exudative detachment resolved, with resulting improvement in visual acuity, and remained quiescent for 3 years. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaapos.2019.02.004DOI Listing

[Importance of interdisciplinary collaboration for optimal treatment of orbital tumors].

HNO 2019 Apr 2. Epub 2019 Apr 2.

Universitätsklinik Köln, Zentrum für Augenheilkunde, Universität zu Köln, Kerpener Straße 62, 50937, Köln, Deutschland.

Optimal treatment of tumors with orbital invasion may exceed the competences of an individual medical specialty and require interdisciplinary cooperation. The aim of this article is to present an interdisciplinary treatment concept based on the examples of intraorbital hemangioma and squamous cell carcinoma of the paranasal sinuses infiltrating the orbit. In addition to a detailed medical history and a complete ophthalmological examination, a detailed imaging technique with standardized echography and tomography methods such as orbital thin-slice CT and/or in many cases MRI is essential for the primary classification of an intraorbital pathology. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00106-019-0659-x
Publisher Site
http://dx.doi.org/10.1007/s00106-019-0659-xDOI Listing
April 2019
5 Reads

Effectiveness of oral propranolol in a patient with neurofibromatosis type 1 and infantile hemangiomas.

G Ital Dermatol Venereol 2019 Mar 29. Epub 2019 Mar 29.

Department of Dermatology and Venereology, "Sapienza" University of Rome, Policlinico Umberto I, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.23736/S0392-0488.19.06179-0DOI Listing

Clinical and radiological outcomes of infantile hemangioma treated with oral propranolol: A long-term follow-up study.

J Dermatol 2019 Mar 27. Epub 2019 Mar 27.

Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Infantile hemangiomas (IH) undergo rapid growth during early infancy followed by gradual involution. After involution, a part of IH remain as residual lesions. Since 2008, oral propranolol has been widely used in the treatment of IH. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1346-8138.14853DOI Listing
March 2019
3 Reads

Benign liver tumors

Rev Prat 2018 12;68(10):1119-1124

Service d'hépatologie.

Benign liver tumors diagnosis. Benign liver tumors are rare events that affect mostly young women. Hepatic hemangioma and focal nodular hyperplasia are not related to oral contraceptions, nor associated with complications, and consequently should not either be treated or followed-up. Read More

View Article

Download full-text PDF

Source
December 2018
2 Reads

Clinical and Ultrasonographic Evaluation of Infantile Periocular Hemangioma Treated With Oral Propranolol.

Ophthalmic Plast Reconstr Surg 2019 Mar 4. Epub 2019 Mar 4.

Poostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Purpose: To evaluate the clinical and ultrasonographic response of periocular infantile capillary hemangioma during treatment with oral propranolol.

Methods: Patients with infantile periocular hemangioma and visual or cosmetic concerns were enrolled in this prospective interventional case series. Propranolol was given at a dose of 2 mg/kg per day for at least 6 months. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/IOP.0000000000001336DOI Listing
March 2019
7 Reads

Hamartoma of the Oral Cavity with Ectopic Meningothelial Elements in Infants: A Rare Entity with Report of Two Cases.

Head Neck Pathol 2019 Mar 6. Epub 2019 Mar 6.

Department of Pathology, Anatomy, and Laboratory Medicine, West Virginia University Robert C. Byrd Health Sciences Center, 2132 HSC-N, P.O. Box 9203, Morgantown, WV, 26506-9203, USA.

Choristomas and hamartomas within the oral cavity are relatively uncommon lesions and may present with diverse clinical and histopathological appearances. In this report, we describe two infant patients with hamartoma with ectopic meningothelial elements involving tongue and maxillary alveolar ridge. To the best of our knowledge, these are the first two cases in which a meningothelial proliferation has been identified in the oral cavity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12105-019-01024-2DOI Listing
March 2019
1 Read

Secondary Congenital Glaucoma Associated With Retro-orbital Infantile Hemangioma: A Masquerade Syndrome.

J Glaucoma 2019 Mar 6. Epub 2019 Mar 6.

University Hospital Nord, Chemin des Bourrely, Marseille, France.

Purpose: The main purpose of this study was to describe a unique case of retro-orbital infantile hemangioma (IH) simulating a congenital glaucoma requiring prompt management with systemic propranolol.

Study Design: This was a case report.

Results: A 2-month-old white female was referred to our department of ophthalmology for progressive, unilateral protrusion of the left eye associated with epiphora. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/IJG.0000000000001227DOI Listing
March 2019
7 Reads

Propranolol-Loaded Mesoporous Silica Nanoparticles for Treatment of Infantile Hemangiomas.

Adv Healthc Mater 2019 Mar 6:e1801261. Epub 2019 Mar 6.

The Economic and Technological Development Zone People's Hospital of Linyi City, Linyi, Shandong, 276023, China.

Infantile hemangioma (IH) is one of the most common neoplasm of infancy. Although with the potential to involute slowly after proliferation, IH has several subsets that could develop severe complications and lead to functional impairment or permanent disfigurement. In the present study, a novel propranolol (PRN) delivery system is developed that encapsulated in mesoporous silica nanoparticles (MSN). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/adhm.201801261DOI Listing
March 2019
2 Reads
4.880 Impact Factor

Diagnosis and Management of Infantile Hemangiomas in the Neonate.

Pediatr Clin North Am 2019 04;66(2):437-459

Division of Dermatology, Ann & Robert H. Lurie Children's Hospital of Chicago, Northwestern University Feinberg School of Medicine, 225 East Chicago Avenue, Box 107, Chicago, IL 60611-2605, USA. Electronic address:

Infantile hemangiomas (IH) are a common benign tumor of infancy, most being uncomplicated and not requiring therapy. Some IH may require treatment; the pediatric provider must be familiar with morphology, distribution, natural history, and associations of IH. Several treatment options are available for IH: current standard of care, oral propranolol. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pcl.2018.12.011DOI Listing
April 2019
1 Read

Central Nervous System Effects of Oral Propranolol for Infantile Hemangioma: A Systematic Review and Meta-Analysis.

J Clin Med 2019 Feb 22;8(2). Epub 2019 Feb 22.

Department of Pharmaceutical Outcomes and Policy, College of Pharmacy, University of Florida, Gainesville, FL 32610, USA.

Concerns about the effects of propranolol on the central nervous system (CNS) in the infantile hemangioma (IH) population have been raised. We conducted a meta-analysis of the CNS and sleep-related effects of oral propranolol in IH patients. PubMed, Embase, Cochrance, Web of Science, and Clinicaltrials. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/jcm8020268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406625PMC
February 2019
2 Reads

Central Effects of Beta-Blockers May Be Due to Nitric Oxide and Hydrogen Peroxide Release Independently of Their Ability to Cross the Blood-Brain Barrier.

Front Neurosci 2019 31;13:33. Epub 2019 Jan 31.

INSERM U1220 Institut de Recherche en Santé Digestive, CHU Purpan, Université Toulouse III Paul Sabatier, Toulouse, France.

Propranolol is the first-line treatment for infants suffering from infantile hemangioma. Recently, some authors raised the question of potential neurologic side effects of propranolol due to its lipophilic nature and thus its ability to passively cross the blood-brain barrier (BBB) and accumulate into the brain. Hydrophilic beta-blockers, such as atenolol and nadolol, where therefore introduced in clinical practice. Read More

View Article

Download full-text PDF

Source
https://www.frontiersin.org/article/10.3389/fnins.2019.00033
Publisher Site
http://dx.doi.org/10.3389/fnins.2019.00033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365417PMC
January 2019
7 Reads

Unsatisfactory response to sirolimus in Maffucci syndrome-associated spindle cell hemangiomas.

Dermatol Ther 2019 Feb 5:e12851. Epub 2019 Feb 5.

Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.

Maffucci syndrome is characterized by multiple benign vascular anomalies and enchondromas present on the distal extremities. Effective treatment options are currently not available for Maffucci syndrome-associated vascular lesions. Sirolimus is a mTOR pathway inhibitor, and has been tried successfully in the treatment of various vascular anomalies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/dth.12851DOI Listing
February 2019
1 Read

MiR-187-3p Enhances Propranolol Sensitivity of Hemangioma Stem Cells.

Cell Struct Funct 2019 Mar 2;44(1):41-50. Epub 2019 Feb 2.

Department of Oromaxillofacial Head and Neck Oncology, Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine.

Infantile hemangioma is the most common soft tissue tumors in childhood. In clinic, propranolol is widely used for infantile hemangioma therapy. However, some of the infantile hemangioma patients display resistance to propranolol treatment. Read More

View Article

Download full-text PDF

Source
https://www.jstage.jst.go.jp/article/csf/advpub/0/advpub_180
Publisher Site
http://dx.doi.org/10.1247/csf.18041DOI Listing
March 2019
10 Reads
1.684 Impact Factor

Efficacy of systemic sirolimus in the treatment of generalized lymphatic anomaly and Gorham-Stout disease.

Pediatr Blood Cancer 2019 May 22;66(5):e27614. Epub 2019 Jan 22.

Vascular Anomalies Center, Division of Hematology/Oncology, Cancer and Blood Disorders Center, Boston Children's Hospital, Boston, Massachusetts.

Background: Generalized lymphatic anomaly (GLA) and Gorham-Stout disease (GSD) are rare complicated lymphatic malformations that occur in multiple body sites and are associated with significant morbidity and mortality. Treatment options have been limited, and conventional medical therapies have been generally ineffective. Emerging data suggest a role for sirolimus as a treatment option for complex lymphatic anomalies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pbc.27614DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428616PMC
May 2019
12 Reads

Prevalence of oral mucosal lesions in young seniors in the Wrocław region.

Dent Med Probl 2018 Oct-Dec;55(4):405-410

Department of Periodontology, Faculty of Dentistry, Wroclaw Medical University, Poland.

Background: The morbidity of certain oral pathologies, for example denture-related stomatitis, burning mouth syndrome (BMS) and benign neoplasms is higher in the elderly. It is necessary to periodically assess the changes in the profile of the occurrence of these diseases and determine the dominant risk factors associated with their incidence.

Objectives: The aim of the study was to evaluate the prevalence of oral mucosal pathologies (in particular, potentially malignant and cancerous disorders) in a randomly selected population of 65-74-year-old residents of Wrocław and Oława, Poland. Read More

View Article

Download full-text PDF

Source
http://www.dmp.umed.wroc.pl/en/article/2018/55/4/405/
Publisher Site
http://dx.doi.org/10.17219/dmp/97310DOI Listing
January 2019
22 Reads

Case of multiple disseminated cutaneous lobular capillary hemangioma that developed while taking oral contraceptive pills.

J Dermatol 2019 Jan 10. Epub 2019 Jan 10.

National Hospital Organization Kyoto Medical Center, Kyoto, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1346-8138.14762DOI Listing
January 2019
1 Read

Topical Timolol Vs. Oral Propranolol for the Treatment of Superficial Infantile Hemangiomas.

Front Oncol 2018 18;8:605. Epub 2018 Dec 18.

Department of Oral and Maxillofacial Surgery, Shanghai Ninth People's Hospital, College of Stomatology Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Infantile hemangiomas (IHs) are the most common vascular tumors of infancy. Oral propranolol has achieved great success in treating IHs since 2008. To minimize the systemic side events caused by oral administration of propranolol, topical timolol started to be applied in the treatment of IHs, especially for superficial lesions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fonc.2018.00605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6305365PMC
December 2018
4 Reads

No Increased Risks Associated with Propranolol Treatment for Infantile Hemangioma in Preterm Infants were Identified at 3 Years of Age.

Am J Clin Dermatol 2019 Apr;20(2):289-293

Department of Dermatology, National Center for Children's Health, Beijing Children's Hospital, Capital Medical University, No. 56 Nanlishi Road, Beijing, 100045, China.

Background: Concerns have been raised that propranolol treatment of infantile hemangioma (IH) may be associated with increased risks of adverse effects and growth impairment in preterm infants due to their immature development.

Objective: This study aimed to find out whether treatment of IH with propranolol in preterm infants is associated with higher incidences of long-term adverse effects and growth impairment in comparison with term infants.

Methods: The clinical data of 55 preterm infants and 180 term infants with IH treated with oral propranolol for 6 months were retrospectively collected and analyzed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s40257-018-00419-1DOI Listing
April 2019
5 Reads
2.519 Impact Factor

A cerebellopontine angle mouse model for the investigation of tumor biology, hearing, and neurological function in NF2-related vestibular schwannoma.

Nat Protoc 2019 02;14(2):541-555

Edwin L. Steele Laboratories, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

Neurofibromatosis type II (NF2) is a disease that lacks effective therapies. NF2 is characterized by bilateral vestibular schwannomas (VSs) that cause progressive and debilitating hearing loss, leading to social isolation and increased rates of depression. A major limitation in NF2 basic and translational research is the lack of animal models that allow the full spectrum of research into the biology and molecular mechanisms of NF2 tumor progression, as well as the effects on neurological function. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41596-018-0105-7DOI Listing
February 2019
18 Reads

Small Bowel Pyogenic Granuloma With Cytomegalovirus Infection in a Patient With Crohn's Disease (Report of a Case and Review of the Literature).

In Vivo 2019 Jan-Feb;33(1):251-254

Department of Pathology, Immunology and Laboratory of Medicine, University of Florida College of Medicine, Gainesville, FL, U.S.A.

Pyogenic granuloma (PG) represents a lobular capillary proliferation commonly seen in the skin or oral mucosa. They are rarely reported in the gastrointestinal tract. The mechanism underlying PG pathogenesis is not well understood. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21873/invivo.11468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364075PMC
April 2019
14 Reads
1.148 Impact Factor

Clinical Practice Guideline for the Management of Infantile Hemangiomas.

Pediatrics 2019 Jan;143(1)

College of Physicians and Surgeons, Columbia University, New York City, New York.

Infantile hemangiomas (IHs) occur in as many as 5% of infants, making them the most common benign tumor of infancy. Most IHs are small, innocuous, self-resolving, and require no treatment. However, because of their size or location, a significant minority of IHs are potentially problematic. Read More

View Article

Download full-text PDF

Source
http://pediatrics.aappublications.org/lookup/doi/10.1542/ped
Publisher Site
http://dx.doi.org/10.1542/peds.2018-3475DOI Listing
January 2019
7 Reads

Non-invasive imaging techniques for early diagnosis of radiation-induced squamous cell carcinoma of the lip.

Rom J Morphol Embryol 2018 ;59(3):949-953

"Victor Babeş" National Institute for Research and Development in Pathology and Biomedical Sciences, Bucharest, Romania;

Ionizing radiation was used in the past for treatment of several benign cutaneous conditions, and particularly hemangiomas. Even though radiotherapy was generally effective, it significantly augmented the risk for malignancies, resulting in a consequent heavy decline of its use for benign conditions. However, radiation-induced neoplasia is still encountered in adult patients irradiated during childhood or adolescence. Read More

View Article

Download full-text PDF

Source
January 2019
6 Reads

Intramuscuar hemangiomas are venous malformations.

J Stomatol Oral Maxillofac Surg 2019 Apr 29;120(2):89-90. Epub 2018 Nov 29.

University of Milan, San Paolo Hospital, Department of Maxillo-Facial Surgery, Via A. DiRudinì, 8, 20100, Milan, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jormas.2018.11.011DOI Listing

Epithelioid hemangioma of the orbit treated with oral propranolol in adult.

Can J Ophthalmol 2018 Dec 3;53(6):e244-e246. Epub 2018 Apr 3.

Pusan National University School of Medicine, Yangsan, South Korea. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcjo.2018.01.022DOI Listing
December 2018
3 Reads

A Large Infantile Capillary Hemangioma of the Eyelid with 5 Years Follow-up.

J Coll Physicians Surg Pak 2018 Dec;28(12):970-971

Department of Pathology, Khyber Medical College, Peshawar, Pakistan.

A five-day baby girl presented with a large mass involving the right upper and lower eyelid obstructing the visual axis completely. She was treated with intralesional triamcinolone acetonide injection under general anesthesia but no change in size of the tumor was observed. Oral beta blocker, propranolol, 1 mg/kg body weight, was given at three months. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.29271/jcpsp.2018.12.970DOI Listing
December 2018
2 Reads

Efficacy and safety of oral atenolol for the treatment of infantile haemangioma: A systematic review.

Australas J Dermatol 2018 Dec 4. Epub 2018 Dec 4.

Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, Chengdu, China.

Recently, several studies have reported their experience in using oral atenolol in patients with infantile haemangioma (IH), especially as an alternative to propranolol, but the efficacy and safety of oral atenolol has not been evaluated. We searched PubMed (Medline), Central, Embase, Web of Science and EBSCOhost (until May 2018) for the eligible studies reporting more than 10 IH patients who were treated with oral atenolol with detailed original data, including outcomes, regimens and adverse events (AEs). The data was standardised and analysed by using R software with meta-package. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ajd.12966DOI Listing
December 2018
8 Reads

Hemangiomas of the tongue and the oral cavity in a myotonic dystrophy type 1 patient: A case report.

Medicine (Baltimore) 2018 Nov;97(48):e13448

Istituto di Ricovero e Cura a Carattere Scientifico Centro Neurolesi "Bonino-Pulejo".

Rationale: Myotonic dystrophy type 1 (DM1) is an autosomal dominant disease caused by a cytosine, guanine, thymine (CTG) trinucleotide repeat expansion in the non-coding region of dystrophia myotonica protein kinase gene, causing a multisystem involvement. To date, few studies have been performed to evaluate skin features in DM1 patients, but none reported on the possible association between the disease and tongue hemangiomas.

Patients Concerns: We report a case of a 63-year-old woman affected by DM1 and presenting, at the intraoral examination, several swelling and buish lesions occurring on buccal and palatal mucosa, and in the anterior two-thirds and margins of the tongue. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000013448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283126PMC
November 2018
4 Reads

Oral benign neoplasms: A retrospective study of 790 patients over a 14-year period.

Acta Otorrinolaringol Esp 2018 Nov 26. Epub 2018 Nov 26.

Postgraduate Program in Oral Pathology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.

Introduction And Objective: Oral benign neoplasms (OBNs) exhibit some features that can guide the professionals to the correct diagnosis and best treatment. Through retrospective studies, medical records can be reviewed to better describe a given population and, furthermore, help clinicians in routine practice. In this context, the objective of this paper was to analyze the cases of OBNs of an oral pathology referral department, from 2003 to 2017, in order to better understand their epidemiological and clinicopathological characteristics. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00016519183010
Publisher Site
http://dx.doi.org/10.1016/j.otorri.2018.04.005DOI Listing
November 2018
13 Reads

A case of venous malformation of the mandible.

Oral Radiol 2019 May 23;35(2):194-197. Epub 2018 May 23.

Department of Oral and Maxillofacial Radiology and Diagnosis, School of Dental Medicine, Tsurumi University, 2-1-3 Tsurumi, Tsurumi Ward, Yokohama, Kanagawa, 230-8501, Japan.

Objective: Vascular malformations occur more rarely in bones than in soft tissue, with 0.5-1.0% of all intraosseous tumors occurring in the mandible. Read More

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11282-018-0335-y
Publisher Site
http://dx.doi.org/10.1007/s11282-018-0335-yDOI Listing
May 2019
15 Reads

Gorham's disease of the mandible: radiological features.

Oral Radiol 2018 May 27;34(2):179-184. Epub 2017 Mar 27.

Department of Oral and Maxillofacial Surgery, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, 56000, Kuala Lumpur, Malaysia.

The most conspicuous element of Gorham's disease is its radiographic features, wherein massive disappearance of the mandible is observed. We report a case of an adolescent boy with massive osteolysis of the mandible in whom the diagnosis of Gorham's disease was made. A 14-year-old boy was referred to the Department of Oral and Maxillofacial Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, for the management of a massive mandibular deformity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11282-017-0282-zDOI Listing
May 2018
15 Reads

Diffusion-weighted magnetic resonance imaging in oral and maxillofacial lesions: preliminary study on diagnostic ability of apparent diffusion coefficient maps.

Oral Radiol 2018 Sep 4;34(3):224-228. Epub 2017 Sep 4.

Department of Radiology, The Nippon Dental University Niigata Hospital, 1-8 Hamaura-cho, Chuo-ku, Niigata, Niigata, 951-8580, Japan.

Objectives: The aim of this study was to investigate the usefulness of diffusion-weighted magnetic resonance imaging (DWI) in oral and maxillofacial lesions, especially the utility of apparent diffusion coefficient (ADC) maps for differential diagnosis of these lesions.

Methods: Fifty-seven patients who underwent magnetic resonance imaging for diagnosis of oral and maxillofacial lesions were included in this prospective study. DWI was performed on a 1. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11282-017-0303-yDOI Listing
September 2018
14 Reads

Hemangioma-like telangiectatic granuloma: A diagnostic pitfall.

J Exp Ther Oncol 2018 Nov;12(4):291-294

MBBS student, Hind Institute of Medical Sciences, Lucknow, U.P, India.

Objective: A telangiectatic granuloma is a localized reactive lesion associated with prolonged irritation to the soft tissues. It may be misdiagnosed as a vascular malformation, hemangiomas, angiosarcomas, etc; as clinical presentation of the lesions resembles each other. Here, we present a case of asymptomatic swelling in the maxilla of a 17-year old female patient. Read More

View Article

Download full-text PDF

Source
November 2018
3 Reads

Endoscope-Assisted Resection of Intramuscular Cavernous Hemangioma Within the Temporal Muscle.

J Craniofac Surg 2019 Jan;30(1):193-195

Division of Oral and Maxillofacial Surgery, Kagawa Prefectural Central Hospital, Kagawa.

Hemangiomas are benign vascular soft tissue tumors, which most frequently occur in the skin or subcutaneous tissue. Intramuscular hemangiomas typically occur in the trunk and extremities and less frequently in the head and neck. Among these, those occurring in the temporalis muscle are extremely rare. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/SCS.0000000000004933DOI Listing
January 2019
10 Reads
0.676 Impact Factor

Oral propranolol therapy in 23 infants with infantile hemangioma.

Arch Plast Surg 2018 Nov 15;45(6):517-524. Epub 2018 Nov 15.

Department of Plastic and Reconstructive Surgery, Institute for Human Tissue Restoration, Yonsei University College of Medicine, Seoul, Korea.

Background: Infantile hemangioma (IH) is a common vascular tumor in pediatric patients, and is commonly treated with propranolol. We describe our experiences with dosage, response to treatment, and side effects in 23 IH patients treated with propranolol.

Methods: For this nonrandomized comparative cohort study, the authors enrolled 23 patients treated with propranolol. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5999/aps.2018.00318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258977PMC
November 2018
26 Reads

Benign Oral Mucosal Lesions: Clinical and Pathological Findings Part I- Benign Oral Mucosal lesions.

J Am Acad Dermatol 2018 Nov 14. Epub 2018 Nov 14.

Department of Dermatology, Boston University School of Medicine, Boston, MA. Electronic address:

A diverse spectrum of benign oral mucosal lesions exists, presenting as either isolated oral findings or in association with dermatological conditions. Oral lesions can closely resemble one another; therefore, it is important for clinicians to be able to recognize their distinctive features and recognize benign versus malignant disease and when a biopsy is warranted. In this continuing medical education series, we review oral anatomy and the clinical attributes of several benign lesions of the oral cavity along with the appropriate management and therapeutic modalities. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01909622183288
Publisher Site
http://dx.doi.org/10.1016/j.jaad.2018.09.061DOI Listing
November 2018
16 Reads

Retrospective clinical study of 296 patients with mass lesions of the tongue.

J Oral Sci 2018 Dec 15;60(4):574-578. Epub 2018 Nov 15.

Department of Oral and Maxillofacial Surgery, Nihon University School of Dentistry.

To better understand the clinical features of mass lesions of the tongue, we retrospectively evaluated frequency, recurrence rate, and complications in 296 patients who had undergone surgery for such lesions. The diagnoses were fibroma (43.6%), mucous cyst (14. Read More

View Article

Download full-text PDF

Source
https://www.jstage.jst.go.jp/article/josnusd/advpub/0/advpub
Publisher Site
http://dx.doi.org/10.2334/josnusd.17-0317DOI Listing
December 2018
14 Reads

Association of Somatic GNAQ Mutation With Capillary Malformations in a Case of Choroidal Hemangioma.

JAMA Ophthalmol 2019 Jan;137(1):91-95

Vascular Biology Program, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts.

Importance: Choroidal hemangiomas are defined by a thickened choroid owing to vessel overgrowth, which may increase the intraocular pressure and lead to glaucoma. Choroidal hemangioma and glaucoma often co-occur in patients with Sturge-Weber syndrome, a rare neurocutaneous disorder characterized by capillary malformations.

Objective: To determine whether the mutation found in most capillary malformations, GNAQ R183Q (c. Read More

View Article

Download full-text PDF

Source
https://jamanetwork.com/journals/jamaophthalmology/fullartic
Publisher Site
http://dx.doi.org/10.1001/jamaophthalmol.2018.5141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382586PMC
January 2019
8 Reads

Clinical and economic impact of surgery for treating infantile hemangiomas in the era of propranolol: overview of single-center experience from La Paz Hospital, Madrid.

Eur J Pediatr 2019 Jan 12;178(1):1-6. Epub 2018 Nov 12.

Department of Pediatric Surgery, Vascular Anomalies Center, Autonoma University of Madrid, Madrid, Spain.

Propranolol has changed the management of infantile hemangiomas (IHs). We summarize the evolution of surgical treatment for IH at La Paz Children's Hospital (Madrid) in the era of propranolol, with a focus on hepatic IHs.Retrospectively, we compared surgical treatment of IHs in children referred during the periods 2004-2009 and 2009-2014. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00431-018-3290-zDOI Listing
January 2019
9 Reads

Interventions for infantile haemangiomas of the skin: abridged Cochrane systematic review and GRADE assessments.

Br J Dermatol 2019 Mar 19;180(3):527-533. Epub 2018 Dec 19.

Cochrane Ecuador, Centro de Investigación en Salud Pública y Epidemiología Clínica (CISPEC), Facultad de Ciencias de la Salud Eugenio Espejo, Universidad Tecnológica Equinoccial, Quito, Ecuador.

Background: Infantile haemangiomas (IH) are soft swellings of the skin that occur in 3-10% of infants. When haemangiomas occur in high-risk areas or when complications develop, active intervention is necessary.

Objective: To update a Cochrane Review assessing the interventions for the management of IH in children. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bjd.17407DOI Listing
March 2019
2 Reads

[Tiempo de respuesta terapéutica al propranolol sistémico en el manejo de hemangiomas subglóticos pediátricos: serie de casos y revisión de la literatura].

Bol Med Hosp Infant Mex 2018 ;75(6):377-382

Departamento de Otorrinolaringología Pediátrica. Hospital Infantil de México Federico Gómez, Ciudad de México, México.

Background: Airway hemangiomas are congenital neoplasms of low incidence. Its clinical presentation consists of obstruction of the upper airway with progressive dyspnea and stridor and the life of the patient at risk. Infantile hemangiomas have an incidence at birth of 2%, increasing to 9% at 12 months of life. Read More

View Article

Download full-text PDF

Source
http://www.bmhim.com/files/bmhi_2018_6_377-382.pdf
Publisher Site
http://dx.doi.org/10.24875/BMHIM.18000043DOI Listing
January 2018
9 Reads

Dermoscopy of venous lake on the lips: A comparative study with labial melanotic macule.

Authors:
Ji Su Lee Je-Ho Mun

PLoS One 2018 31;13(10):e0206768. Epub 2018 Oct 31.

Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.

Background: Venous lake (VL) is a common vascular tumor occurring on the lips in the elderly. VL is sometimes difficult to distinguish from melanotic lesions such as labial melanotic macule (LMM) or oral malignant melanoma. However, the dermoscopic features of VL have not been sufficiently established in the literature. Read More

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206768PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209377PMC
April 2019
4 Reads

Lingual cavernous hemangioma in a Nepalese boy-'A Difficult Associate!!!'

J Surg Case Rep 2018 Oct 23;2018(10):rjy283. Epub 2018 Oct 23.

Department of Pathology, Grande International Hospital, Dhapasi, Kathmandu, Nepal.

Hemangiomas are benign tumors comprising of ectatic blood vessels. Although common in the head and neck region, those occurring within the oral cavity and tongue are exceedingly rare. We report a 5-year-old boy with a swelling over the anterior third of tongue post failed conservative therapy eventually treated with surgical excision and confirmed histologically as a cavernous hemangioma probably first of its kind reported from Nepal. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jscr/rjy283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198281PMC
October 2018
24 Reads

Propranolol suppresses HUVEC viability, migration, VEGF expression, and promotes apoptosis by downregulation of miR-4295.

J Cell Biochem 2019 Apr 28;120(4):6614-6623. Epub 2018 Oct 28.

Department of Burn and Plastic Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China.

Infantile hemangioma (IH) is a common benign tumor. Human umbilical vein endothelial cells (HUVECs) have the potential of stem cells, which has been widely used in vascular endothelial cell experiments. Oral propranolol was first reported to treat hemangioma in 2008. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jcb.27957
Publisher Site
http://dx.doi.org/10.1002/jcb.27957DOI Listing
April 2019
16 Reads

Synovial Hemangioma of the Temporomandibular Joint: Case Report.

J Oral Facial Pain Headache Fall 2018;32(4):e45-e48

Hemangiomas are benign vasoformative neoplasms or developmental conditions of endothelial origin. Synovial hemangiomas arise from a synovial lined surface within a joint space. This report describes a case of synovial hemangioma of the left temporomandibular joint (TMJ) in a 65-year-old male patient. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.11607/ofph.1986DOI Listing
February 2019
3 Reads

Effects of propranolol therapy in Moroccan children with infantile hemangioma.

Arch Pediatr 2018 Nov 22;25(8):449-451. Epub 2018 Oct 22.

Department of dermatology's diseases, CHU Ibn Rochd, 20050 Casablanca, Morocco; Faculty of medicine and pharmacy, University Hassan II, Casablanca, Morocco.

Infantile hemangiomas are the most common childhood vascular tumors. Propranolol is a β-adrenergic blocker that has proven effective in the treatment of this tumor. Numerous studies around the world have been published, describing satisfactory responses in pediatric populations with a higher cure rate and fewer adverse effects than when using corticosteroids. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0929693X183020
Publisher Site
http://dx.doi.org/10.1016/j.arcped.2018.09.002DOI Listing
November 2018
14 Reads

Virome Analysis Reveals No Association of Head and Neck Vascular Anomalies with an Active Viral Infection.

In Vivo 2018 Nov-Dec;32(6):1323-1331

Department of Otolaryngology/Head and Neck Surgery, University Hospital Giessen and Marburg, Marburg, Germany

Background/aim: Vascular anomalies encompass different vascular malformations [arteriovenous (AVM), lymphatic (LM), venous lymphatic (VLM), venous (VM)] and vascular tumors such as hemangiomas (HA). The pathogenesis of vascular anomalies is still poorly understood. Viral infection was speculated as a possible underlying cause. Read More

View Article

Download full-text PDF

Source
http://iv.iiarjournals.org/lookup/doi/10.21873/invivo.11382
Publisher Site
http://dx.doi.org/10.21873/invivo.11382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365735PMC
January 2019
17 Reads

Multifocal congenital pyogenic granuloma successfully treated with oral propranolol.

Pediatr Dermatol 2019 Jan 15;36(1):e41-e43. Epub 2018 Oct 15.

Dermatopathology Division, Department of Pathology and Laboratory Medicine, Sylvester Comprehensive Cancer Center and Miller School of Medicine, University of Miami, Miami, Florida, USA.

Disseminated congenital pyogenic granuloma (DCPG) is an uncommon condition. Individual lesions of DCPG share clinical and histologic similarities with infantile hemangioma (IH); endothelial glucose transporter 1 (GLUT-1), which is highly expressed in IH but generally not in pyogenic granulomas (PG), is an important diagnostic tool. Treatment for DCPG remains difficult. Read More

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/pde.13689
Publisher Site
http://dx.doi.org/10.1111/pde.13689DOI Listing
January 2019
9 Reads