MicroRNA profiling reveals dysregulated microRNAs and their target gene regulatory networks in cemento-ossifying fibroma.
- Thaís Dos Santos Fontes Pereira,
- João Artur Ricieri Brito,
- André Luiz Sena Guimarães,
- Carolina Cavaliéri Gomes,
- Júlio Cesar Tanos de Lacerda,
- Wagner Henriques de Castro,
- Roney Santos Coimbra,
- Marina Gonçalves Diniz,
- Ricardo Santiago Gomez
J Oral Pathol Med 2017 Oct 15. Epub 2017 Oct 15.
Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais (UFMG), Belo HorizonteBrazil.
Background: Cemento-ossifying fibroma (COF) is a benign fibro-osseous neoplasm of uncertain pathogenesis and its treatment results morbidity. MicroRNAs (miRNA) are small non-coding RNAs that regulate gene expression and may represent therapeutic targets. The purpose of the study was to generate a comprehensive miRNA profile of COF compared to normal bone. Read More