Clinicopathologic and Molecular Characteristics of Familial Cherubism with Associated Odontogenic Tumorous Proliferations.
- Prokopios P Argyris,
- Rajaram Gopalakrishnan,
- Ying Hu,
- Ernst J Reichenberger,
- Ioannis G Koutlas
Head Neck Pathol 2017 Jul 18. Epub 2017 Jul 18.
Division of Oral and Maxillofacial Pathology, School of Dentistry, University of Minnesota, 515 Delaware Street SE 16-206B, Minneapolis, MN, 55455, USA.
Cherubism is a rare autosomal dominant condition affecting the jaws and caused by mutations in the gene encoding for the adapter protein SH3BP2 that maps to chromosome 4p16.3. Cherubism is characterized by symmetrically developing bone lesions in the maxilla and mandible. Read More