1,909 results match your criteria Oral Fibromas and Fibromatoses


Bringing benign ectomesenchymal odontogenic tumours to the lab: an in vitro study using an organotypic culture model.

J Oral Pathol Med 2018 Dec 16. Epub 2018 Dec 16.

Department of Pathology, Basic Sciences Institute, Universidade Federal de Minas Gerais-UFMG, Belo Horizonte, Brazil.

Background: Benign neoplasms exhibit most of the cellular phenomena considered hallmarks of cancer, except the capacity to metastasize. Thus, the elucidation of the mechanisms associated with the progression of benign neoplasms may complement and clarify the mechanisms involved in carcinogenesis. Benign odontogenic tumours often result in facial deformities and morbidities, and have complex pathogenesis, mainly due to the diversity of interactions between the odontogenic epithelium and the ectomesenchyme. Read More

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http://dx.doi.org/10.1111/jop.12812DOI Listing
December 2018
1 Read

Oral benign neoplasms: A retrospective study of 790 patients over a 14-year period.

Acta Otorrinolaringol Esp 2018 Nov 26. Epub 2018 Nov 26.

Postgraduate Program in Oral Pathology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.

Introduction And Objective: Oral benign neoplasms (OBNs) exhibit some features that can guide the professionals to the correct diagnosis and best treatment. Through retrospective studies, medical records can be reviewed to better describe a given population and, furthermore, help clinicians in routine practice. In this context, the objective of this paper was to analyze the cases of OBNs of an oral pathology referral department, from 2003 to 2017, in order to better understand their epidemiological and clinicopathological characteristics. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00016519183010
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http://dx.doi.org/10.1016/j.otorri.2018.04.005DOI Listing
November 2018
3 Reads

Surgical correction of residual facial deformity following conservative excision of a giant maxillary ossifying fibroma: A case report.

Medicine (Baltimore) 2018 Nov;97(47):e13186

Department of Plastic and Reconstructive Surgery.

Rationale: Ossifying fibroma (OF) is a benign fibro-osseous lesion that can develop in the oral and maxillofacial region. OF is more common in females and has a marked predilection for the mandible, occurring rarely in the maxilla. Lesions grow slowly and are usually asymptomatic until growth produces an obvious swelling, pain, paresthesia, and facial deformity. Read More

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http://dx.doi.org/10.1097/MD.0000000000013186DOI Listing
November 2018
2 Reads

Benign Oral Mucosal Lesions: Clinical and Pathological Findings Part I- Benign Oral Mucosal lesions.

J Am Acad Dermatol 2018 Nov 14. Epub 2018 Nov 14.

Department of Dermatology, Boston University School of Medicine, Boston, MA. Electronic address:

A diverse spectrum of benign oral mucosal lesions exists, presenting as either isolated oral findings or in association with dermatological conditions. Oral lesions can closely resemble one another; therefore, it is important for clinicians to be able to recognize their distinctive features and recognize benign versus malignant disease and when a biopsy is warranted. In this continuing medical education series, we review oral anatomy and the clinical attributes of several benign lesions of the oral cavity along with the appropriate management and therapeutic modalities. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01909622183288
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http://dx.doi.org/10.1016/j.jaad.2018.09.061DOI Listing
November 2018
5 Reads

Retrospective clinical study of 296 patients with mass lesions of the tongue.

J Oral Sci 2018 Nov 15. Epub 2018 Nov 15.

Department of Oral and Maxillofacial Surgery, Nihon University School of Dentistry.

To better understand the clinical features of mass lesions of the tongue, we retrospectively evaluated frequency, recurrence rate, and complications in 296 patients who had undergone surgery for such lesions. The diagnoses were fibroma (43.6%), mucous cyst (14. Read More

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https://www.jstage.jst.go.jp/article/josnusd/advpub/0/advpub
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http://dx.doi.org/10.2334/josnusd.17-0317DOI Listing
November 2018
3 Reads

Peripheral giant cell granuloma manifestation in pregnancy.

Indian J Dent Res 2018 Sep-Oct;29(5):678-682

Department of Periodontology, Government Dental College and Hospital, Mumbai, Maharashtra, India.

The peripheral giant cell granuloma (PGCG) is a benign oral lesion occurring on the gingiva and alveolar ridge. It is the most common oral lesion and occurs at an average age of 30 years. The upsurge in the levels of estrogen and progesterone in pregnancy leads to a plethora of changes in various parts of human body, including the oral cavity. Read More

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http://dx.doi.org/10.4103/ijdr.IJDR_110_17DOI Listing
November 2018
1 Read

Mouth floor tumour in an elderly woman.

J Stomatol Oral Maxillofac Surg 2018 Oct 30. Epub 2018 Oct 30.

Université de Lille, service de chirurgie Maxillo-Faciale et stomatologie, hôpital Roger-Salengro, CHU de Lille, 59000 Lille,France.

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http://dx.doi.org/10.1016/j.jormas.2018.10.009DOI Listing
October 2018

Oral and Extraoral Intermediate Tumors: Are MMP-9 and Ki-67 Biomarkers Correlated to Their High Recurrence Rates?

Appl Immunohistochem Mol Morphol 2018 Oct 24. Epub 2018 Oct 24.

Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland, Baltimore, MA.

Intermediate tumors of the head and neck fall in the borderline category. They are clinically aggressive tumors with no malignant phenotyping. They are locally infiltrative and have high recurrence rate with less chances to metastasize. Read More

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http://dx.doi.org/10.1097/PAI.0000000000000703DOI Listing
October 2018
5 Reads

A clinicopathologic study on central odontogenic fibroma: with special reference to amyloid variant.

Oral Surg Oral Med Oral Pathol Oral Radiol 2018 Dec 6;126(6):513-520. Epub 2018 Sep 6.

Department of Oral Pathology, Peking University School and Hospital of Stomatology, Beijing, PR China. Electronic address:

Objective: The aim of this study was to clarify the clinicopathologic features of central odontogenic fibroma (OF), especially the amyloid variant, and to discuss its association with the Langerhans cell variant of calcifying epithelial odontogenic tumor (CEOT).

Study Design: The clinicopathologic features and immunophenotypes of 17 OFs, including 6 amyloid variants, were analyzed. The Langerhans cell variant of CEOT is reviewed, and its relationship with OF is discussed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22124403183116
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http://dx.doi.org/10.1016/j.oooo.2018.08.019DOI Listing
December 2018
5 Reads

Epidemiology of oral mucosal lesions in Slovenia.

Radiol Oncol 2018 Sep 11;52(3):263-266. Epub 2018 Sep 11.

Private Dental Practice, Ljubljana, Slovenia.

Background Among the diseases of oral mucosa, malignant tumors are the most dangerous, but not the most common lesions that might appear in the oral cavity. Since most of the studies are focused on the detection of cancer in the oral cavity, we were interested in detecting the frequency of benign changes of the oral mucosa in Slovene population. Oral mucosal lesions are important pointer of oral health and quality of life, especially in elderly. Read More

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http://dx.doi.org/10.2478/raon-2018-0031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137360PMC
September 2018
1 Read

[A clinicopathological retrospective epidemiological analysis of benign tumors and tumor-like lesions in the oral and maxillofacial region, diagnosed at the University of Szeged, Department of Oral Medicine (1960-2014)].

Orv Hetil 2018 Sep;159(37):1516-1524

Fogorvostudományi Kar, Szájsebészeti Tanszék, Szegedi Tudományegyetem Szeged.

Introduction: In a clinicopathological retrospective epidemiological study we investigated benign tumors and tumor-like lesions located in the orofacial region, diagnosed at the Universiy of Szeged, Department of Oral Medicine.

Method: During a 54-year period (1960-2014), 14 661 biopsies were taken. The included subjects were 7491 patients diagnosed with benign tumors and tumor-like lesions. Read More

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http://dx.doi.org/10.1556/650.2018.31164DOI Listing
September 2018
9 Reads

Myofibroblastic lesions in the oral cavity: Immunohistochemical and ultrastructural analysis.

Oral Dis 2018 Aug 31. Epub 2018 Aug 31.

Postgraduate Program, Oral Pathology, Federal University of Rio Grande do Norte, Natal, Brazil.

Objective: To immunohistochemically characterize a group of oral myofibroblastic lesions (MLs) and to evaluate the ultrastructural features of myofibroblasts.

Material And Methods: Using a tissue microarray technique (TMA), cases of myofibroma (MF), of nodular fasciitis (NF), of desmoplastic fibroma (DF), and of myofibroblastic sarcoma (MS) from the Universidad Autónoma Metropolitana Xochimilco, and a Private Oral Pathology Service in Mexico City were stained with antibodies against alpha-smooth muscle actin (α-SMA), H-caldesmon, vimentin, desmin, β-catenin, CD34, anaplastic lymphoma protein kinase (ALK-1), and Ki-67.

Results: Nineteen of the 22 MF cases, 2/5 of the NF cases, 1/10 of the DF cases, and 1/2 of the MS cases were positive for α-SMA. Read More

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http://dx.doi.org/10.1111/odi.12972DOI Listing
August 2018
8 Reads

Recurrent peripheral ossifying fibroma: Case report.

Dent Med Probl 2018 Jan-Mar;55(1):83-86

Department of Periodontology, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Mangalore, India.

Most of the reactive lesions in the oral cavity arise from gingiva. Fibroma, focal fibrous hyperplasia, pyogenic granuloma, and peripheral ossifying fibroma are the commonly encountered lesions of gingiva. Peripheral ossifying fibroma (POF) frequently arises from the peripheral tissues like gingiva. Read More

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http://dx.doi.org/10.17219/dmp/80863DOI Listing
August 2018
11 Reads

Central odontogenic fibroma: An updated systematic review of cases reported in the literature with emphasis on recurrence influencing factors.

J Craniomaxillofac Surg 2018 Oct 7;46(10):1753-1757. Epub 2018 Aug 7.

Oral Surgery and Pathology Department, João de Barros Barreto University Hospital, Federal University of Pará, Belém, Pará, Brazil. Electronic address:

Purpose: To integrate the available data published on central odontogenic fibroma (COF) into a comprehensive analysis of its clinical/radiologic/histological features.

Methods: An electronic search was undertaken in September 2017. Eligibility criteria included publications reporting cases of COF having enough clinical, radiological and histological information to confirm the diagnosis. Read More

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http://dx.doi.org/10.1016/j.jcms.2018.07.025DOI Listing
October 2018
7 Reads

Cardiac Fibroma with Ventricular Tachycardia: An Unusual Clinical Presentation of Nevoid Basal Cell Carcinoma Syndrome.

Mol Syndromol 2018 Jul 19;9(4):219-223. Epub 2018 May 19.

Division of Human Genetics.

Pediatric cardiac tumors are rare and often benign with an incidence of approximately 0.03-0.32% and can be associated with genetic conditions. Read More

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http://dx.doi.org/10.1159/000489056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103330PMC
July 2018
2 Reads

An Immature Ten-year Long-standing Case of Ossifying Fibroma.

Cureus 2018 Jun 11;10(6):e2782. Epub 2018 Jun 11.

Department of Oral Medicine and Diagnostic Sciences, CWRU School of Dental Medicine, Cleveland, USA.

Ossifying fibroma is a rare benign bone neoplasm common in middle age, with definite female predominance. Here, we describe a case of an ossifying fibroma in a 36-year-old female, with a right facial deformity. The lesion had been present for almost 10 years. Read More

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http://dx.doi.org/10.7759/cureus.2782DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089475PMC
June 2018
10 Reads

Microvessel density and cell proliferation in juvenile ossifying fibroma: A comparative study with central ossifying fibroma.

Ann Diagn Pathol 2018 Oct 4;36:44-49. Epub 2018 Aug 4.

Department of Oral Pathology, São Leopoldo Mandic Institute and Research Center, Rua José Rocha Junqueira, 13, CEP 13045-610 Campinas, SP, Brazil.. Electronic address:

Considered as an aggressive counterpart of central ossifying fibroma (OF), juvenile ossifying fibroma (JOF) is a benign fibro-osseous neoplasm characterized by an unpredictable destructive behavior, elevated morbidity, mutilating treatment and high potential for local recurrences. The aim of this study is to compare the analysis for cell proliferation and vascular markers between JOF and OF. Cell proliferation index was measured by Ki-67 and Mcm-2 expression and microvessel density (MVD) was obtained by the immunoexpression of CD34/CD105. Read More

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http://dx.doi.org/10.1016/j.anndiagpath.2018.08.001DOI Listing
October 2018
1 Read

Recurrent juvenile psammomatoid ossifying fibroma with secondary aneurysmal bone cyst of the maxilla: a case report and review of literature.

Clin Pract 2018 Jul 24;8(3):1085. Epub 2018 Jul 24.

Department of Maxillofacial Surgery and Diagnostic Sciences, Division of Oral Pathology, College of Dentistry, Jazan University, Jazan, Saudi Arabia.

Juvenile ossifying fibroma is a benign fibro-osseous lesion commonly affecting the extra-gnathic craniofacial skeleton of the young individuals. The psammomatoid and trabecular variants are its two histopathological subtypes having distinctive clinico-pathological characteristics. Secondary aneurysmal bone cysts are frequently reported to arise in the pre-existing fibro-osseous lesions but rarely reported in the psammmomatoid variant of the juvenile ossifying fibroma. Read More

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http://dx.doi.org/10.4081/cp.2018.1085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060481PMC
July 2018
5 Reads

Evaluation and Immunolocalization of BMP4 and FGF8 in Odontogenic Cyst and Tumors.

Anal Cell Pathol (Amst) 2018 12;2018:1204549. Epub 2018 Jul 12.

Department of Conservative Dentistry and Endodontics, Daswani Dental College and Research Centre, Kota, India.

Growth factors like bone morphogenetic protein 4 (BMP4) and fibroblast growth factor 8 (FGF8) play a major role in organogenesis and specifically in odontogenesis. They are also believed to have a role in oncogenesis. Thus, any discrepancies in their standard behavior and activity would lead to serious abnormalities including odontogenic cyst and tumors. Read More

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http://dx.doi.org/10.1155/2018/1204549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6069700PMC
October 2018
1 Read

Treatment of cryotherapy and orthotopic transplantation following chondromyxoid fibroma of zygomatic bone: A case report.

Medicine (Baltimore) 2018 Aug;97(31):e11707

Department of Oral, Maxillofacial, Cephalic and Cervical Tumors, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Huangpu District, Shanghai, China.

Introduction: Chondromyxoid fibrotherma (CMF) is a rare benign cartilage tumor that occurs more frequently in young males at the age of 20 to 30. It occurs more frequently on long bones, but rarely involves craniofacial bones.

Case Presentation: This study mainly introduced a 30-year-old male with CMF of zygomatic bone. Read More

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http://dx.doi.org/10.1097/MD.0000000000011707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081066PMC
August 2018
3 Reads

Central Odontogenic Fibroma: A Case Report.

Cureus 2018 Apr 30;10(4):e2556. Epub 2018 Apr 30.

Armed Forces Institute of Dentistry, CMH Lahore Medical College and Institute of Dentistry, Lahore, PAK.

A central odontogenic fibroma (COF) is a rare tumor of odontogenic origin with a diverse histopathology found in both the mandible and the maxilla. It can often be difficult to diagnose; therefore, it is necessary to evaluate the clinical, radiographic, and histopathological analyses of COF and co-relate them in a manner to make definitive diagnosis easier for the treating physician. Herein, we report and discuss the first known case of central odontogenic fibroma in Pakistan: a 16-year-old boy presenting as a hard bony painless swelling of the left mandibular region. Read More

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http://dx.doi.org/10.7759/cureus.2556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6053285PMC
April 2018
1 Read

Corrigendum to "Fibrous Dysplasia versus Juvenile Ossifying Fibroma: A Dilemma".

Case Rep Dent 2018 14;2018:5813805. Epub 2018 Jan 14.

Department of Oral Medicine and Radiology, AJ Institute of Dental Sciences, Mangalore, Karnataka, India.

[This corrects the article DOI: 10.1155/2016/6439026.]. Read More

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http://dx.doi.org/10.1155/2018/5813805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821960PMC
January 2018
1 Read

Angioleiomyoma of the oral cavity: a case report and brief review of the literature.

J Korean Assoc Oral Maxillofac Surg 2018 Jun 26;44(3):136-139. Epub 2018 Jun 26.

Department of Oral Medicine and Pathology, Periodontology and Implant Biology, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece.

This study presents a case of an oral angioleiomyoma along with its clinical diagnostic approach and laboratory confirmation. The differential diagnosis, especially from angioleiomyosarcoma, is also included. A 51-year-old patient presented with a tumor-like lesion on his upper labial mucosa. Read More

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http://dx.doi.org/10.5125/jkaoms.2018.44.3.136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024062PMC
June 2018
1 Read

Peripheral Ameloblastic Fibroma of Anterior Maxillary Gingiva Simulating Pyogenic Granuloma.

J Coll Physicians Surg Pak 2018 Jul;28(7):575

Department of Oral and Maxillofacial Pathology, King George's Medical University (KGMU), Lucknow, Uttar Pradesh, India.

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http://dx.doi.org/10.29271/jcpsp.2018.07.575DOI Listing
July 2018
0.318 Impact Factor

Distribution of biopsied non plaque-induced gingival lesions in a Chilean population according to the classification of periodontal diseases.

BMC Oral Health 2018 Jun 19;18(1):112. Epub 2018 Jun 19.

Department of Pathology, Faculty of Dentistry, University of Chile, Sergio Livingstone 943, Independencia, Santiago, Chile.

Background: Many gingival lesions are not induced by plaque. The aim of this study was to analyze the frequency of biopsied non-plaque-induced gingival lesions (NPIGL) in a Chilean population.

Methods: One thousand twelve cases of biopsied gingival lesions with confirmed anatomopathologic diagnosis were included, from the records of the Oral Pathology Referral Institute (OPRI), Faculty of Dentistry, University of Chile, between years 1990 and 2009. Read More

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http://dx.doi.org/10.1186/s12903-018-0567-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009048PMC
June 2018
3 Reads

Prevalence and Distribution of Oral Mucosal Lesions by Sex and Age Categories: A Retrospective Study of Patients Attending Lebanese School of Dentistry.

Int J Dent 2018 17;2018:4030134. Epub 2018 May 17.

Faculty of Pharmacy, Lebanese University, Beirut, Lebanon.

Background: Prevalence and distribution of oral mucosal lesions in a sample of Lebanese population attending the School of Dentistry of Lebanese University is necessary to evaluate their oral health situation.

Objectives: The aim of the present study was to determine the prevalence and distribution of oral mucosal lesions of patients attending the School of Dentistry.

Methods: A descriptive study was carried out by retrospectively examining a total of 231 medical and clinical examination record files of patients, attending the School of Dentistry Lebanese University for multidisciplinary dental treatments. Read More

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https://www.hindawi.com/journals/ijd/2018/4030134/
Publisher Site
http://dx.doi.org/10.1155/2018/4030134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985080PMC
May 2018
6 Reads

Juvenile Trabecular Ossifying Fibroma-a Case Report.

Indian J Surg Oncol 2018 Jun 21;9(2):260-264. Epub 2018 Apr 21.

5Department of Oral and Maxillofacial Surgery Specialized, Babol University of Medical Sciences, Babol, Iran.

Ossifying fibroma is a benign osteogenic mesenchymal tumor that is classified in the fibro-osseous lesions. Fibro-osseous lesions contain minerals, blood vessels, and giant cells that have the same radiographic and pathologic features but have different clinical behaviors, and were replaced with the normal bone. These lesions include fibrous dysplasia, cemento-osseous dysplasia, and ossifying fibroma. Read More

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http://dx.doi.org/10.1007/s13193-018-0759-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984869PMC
June 2018
1 Read

Comparsion of staining characteristics of Toto bodies.

Biotech Histochem 2018 21;93(5):336-339. Epub 2018 May 21.

a Department of Oral and Maxillofacial Pathology , St. Joseph Dental College , Eluru 534004 , Andhra Pradesh , India.

Toto bodies are eosinophilic structures that resemble the cells of the superficial cell layer of the oral epithelium. Toto bodies commonly are associated with inflammatory gingival and other mucosal lesions including pyogenic granuloma, irritational fibroma, epulis fissuratum, peripheral giant cell granuloma and inflammatory hyperplastic gingivitis. We evaluated staining characteristics of Toto bodies to establish their origin and to identify their significance in lesions. Read More

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https://www.tandfonline.com/doi/full/10.1080/10520295.2018.1
Publisher Site
http://dx.doi.org/10.1080/10520295.2018.1441441DOI Listing
December 2018
24 Reads

The role of macrophages and eosinophils in reactive lesions of the oral cavity.

J Oral Maxillofac Pathol 2018 Jan-Apr;22(1):147

Department of Oral and Maxillofacial Pathology, Dental and Periodontal Research Centre, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.

Background: Many studies have reported that macrophages and eosinophils are involved in the pathogenesis of several diseases. To the best of our knowledge, this is the first study comparing macrophages and eosinophils in oral reactive lesions.

Aims: In this study, we aimed to determine the contribution of macrophages and eosinophils to the pathogenesis of oral reactive lesions and the relationships between these biomarkers and the diverse histopathologic features. Read More

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http://dx.doi.org/10.4103/jomfp.JOMFP_15_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917529PMC
May 2018
4 Reads

Incidence of reactive hyperplastic lesions in the oral cavity: a 10 year retrospective study in Santa Catarina, Brazil.

Braz J Otorhinolaryngol 2018 Apr 17. Epub 2018 Apr 17.

Department of Pathology, Federal University of Santa Catarina, Florianópolis, SC, Brazil.

Introduction: Reactive hyperplastic lesions develop in response to a chronic injury simulating an exuberant tissue repair response. They represent some of the most common oral lesions including inflammatory fibrous hyperplasia, oral pyogenic granuloma, giant cell fibroma, peripheral ossifying fibroma, and peripheral giant cell lesions.

Objective: The incidence of those lesions was investigated in an oral pathology service, and the clinical characteristics, associated etiological factors, concordance between the clinical and histopathological diagnostic was determined. Read More

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http://dx.doi.org/10.1016/j.bjorl.2018.03.006DOI Listing
April 2018
8 Reads

Oral Bilateral Collagenous Fibroma: A previously unreported case and literature review.

J Clin Exp Dent 2018 Jan 1;10(1):e96-e99. Epub 2018 Jan 1.

MSc, Post Graduate Program in Dentistry, School of Dentistry, Federal University of Pelotas, Pelotas-RS, Brazil.

Collagenous fibroma, also known as desmoplastic fibroblastoma, is a rare benign slow growing tumor particularly uncommon in the oral cavity. The aim of this study was to analyze the clinical and histopathological features of an oral collagenous fibroma as well as to compare this data with those reported in an English-literature review. The thirteenth case of collagenous fibroma in the oral cavity and the first to present clinically as a bilateral mass was described. Read More

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http://dx.doi.org/10.4317/jced.54123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899808PMC
January 2018
1 Read

Clinicopathological investigation of odontogenic fibroma in tuberous sclerosis complex.

Int J Oral Maxillofac Surg 2018 Jul 10;47(7):918-922. Epub 2018 Apr 10.

Department of Radiation Oncology, Gunma University Graduate School of Medicine, Gunma, Japan.

Tuberous sclerosis complex (TSC) is an autosomal dominant inherited disease characterized by systemic hamartoma and diverse systemic features. TSC1 and TSC2 are the causative genes, and mental retardation, epileptic seizures, and facial angiofibroma develop in many patients with the disease. The case of a patient with TSC who developed a central odontogenic fibroma of the mandible is reported here. Read More

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http://dx.doi.org/10.1016/j.ijom.2018.03.025DOI Listing
July 2018
2 Reads

CT and MR imaging characteristics of histological subtypes of head and neck ossifying fibroma.

Dentomaxillofac Radiol 2018 Jul 11;47(6):20180085. Epub 2018 Apr 11.

1 Department of Radiology, Gifu University School of Medicine , Gifu , Japan.

Objectives: The current study aimed to assess CT and MRI characteristics of histological subtypes of head and neck ossifying fibroma (OF).

Methods: 12 patients with histopathologically-proven head and neck OF were included in this study. Lesions were pathologically classified into three histological subtypes: eight cement-OFs (COFs), three juvenile psammomatoid OFs (JPOFs), and one juvenile trabecular OF (JTOF). Read More

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http://dx.doi.org/10.1259/dmfr.20180085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196048PMC
July 2018
1 Read

Ossifying Fibromyxoid tumor of soft parts in head and neck: case report and literature review.

Diagn Pathol 2018 Mar 27;13(1):21. Epub 2018 Mar 27.

Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, 22 South Zhongguancun Avenue, Beijing, 100081, People's Republic of China.

Background: Ossifying fibromyxoid tumor of soft parts (OFMT), is a rare but morphologically distinctive neoplasm of uncertain histogenesis that most frequently affects middle-aged male adults. Clinically, it usually presents as a slowly enlarging, small, circumscribed mass, which in most cases is painless. OFMT is most frequently found within the subcutaneous tissues of extremities or trunk, and rarely in the oral/head and neck region. Read More

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http://dx.doi.org/10.1186/s13000-018-0699-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870216PMC
March 2018
2 Reads
2.410 Impact Factor

Giant Peripheral Ossifying Fibroma of the Posterior Mandible-A Rare Case Report.

Iran J Pathol 2017 1;12(4):397-401. Epub 2017 Oct 1.

Dept. of Oral Pathology & Microbiology, Subharti Dental College & Hospital, Meerut, India.

Large, atypical peripheral ossifying fibromas are known as giant peripheral ossifying fibromas. These lesions have often been associated with heterogeneous clinical and radiographic characteristics subsequently leading to their misdiagnosis. Biopsies have been the gold standard for the diagnosis of such lesions. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844686PMC
October 2017

Large mandibular central odontogenic fibroma documented over 20 years: A case report.

Int J Surg Case Rep 2017 24;41:481-488. Epub 2017 Nov 24.

Centre for Oral and Maxillofacial Surgery, University of Dental Medicine and Oral Health, Danube Private University, Steiner Landstraße 124, 3500 Krems-Stein, Austria. Electronic address:

Introduction: Central odontogenic fibroma (COF) is a rare, benign, slow-growing intraosseous odontogenic tumor, and accounts for 0.1% of all odontogenic tumors. It is often confused with other entities, such as keratocysts, ameloblastomas, and odontogenic myxomas. Read More

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http://dx.doi.org/10.1016/j.ijscr.2017.11.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711670PMC
November 2017
2 Reads

Does a Vascularized Fibula Free Bone Grafted Immediately After Hemimandibulectomy in a Child Grow or Relapse During Adolescence?

J Craniofac Surg 2018 Jul;29(5):e444-e449

Section of Maxillofacial Surgery, Department of Maxillofacial and Neck Reconstruction.

For young growing children before the end of skeletal maturity, the growth activity of the grafted bone after hemimandibulectomy is not well-known. After an adolescence, such a patient may have facial deformity because the anterior growth point of the mandible is in the condylar neck. A 13-year-old boy was performed hemimandibulectomy with immediate mandibular reconstruction by fibula free flap (FFF) because of a huge ameloblastic fibroma. Read More

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http://Insights.ovid.com/crossref?an=00001665-900000000-9576
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http://dx.doi.org/10.1097/SCS.0000000000004461DOI Listing
July 2018
8 Reads

A curious case of central odontogenic fibroma: A novel perspective.

J Oral Maxillofac Pathol 2018 Jan;22(Suppl 1):S16-S19

Department of Oral Pathology and Microbiology, Manipal College of Dental Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, India.

We appraise a case of central odontogenic fibroma (COF) with unusual histologic features of entrapped neural elements and mast cells. The presence of mast cells attributed to the release of stem cell factor, the principal growth and activating factor of mast cells. A putative role for C-kit and mast cells in the pathogenesis of COF is described. Read More

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http://dx.doi.org/10.4103/jomfp.JOMFP_156_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824509PMC
January 2018
2 Reads

Fibrotic encapsulation of orthodontic appliance in palate.

J Indian Soc Periodontol 2017 Sep-Oct;21(5):427-428

Department of Periodontology, Meenakshi Ammal Dental College and Hospital, Chennai, Tamil Nadu, India.

Iatrogenic trauma though not serious is very common in dental practice. Orthodontic treatment can inflict such injuries as they are prolonged over a long period of time. Ill-fabricated orthodontic appliances, such as wires and brackets, or the patients' habits such as application of constant pressure over the appliance can traumatize the adjacent oral soft tissues. Read More

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http://dx.doi.org/10.4103/jisp.jisp_133_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827514PMC
March 2018
2 Reads

Folliculin mutation-negative trichodiscomas in a patient with multiple endocine neoplasia type I syndrome.

Dermatol Online J 2017 Aug 15;23(8). Epub 2017 Aug 15.

Harvard Medical School, Boston, Massachusetts.

Mycosis fungoides (MF) is the most common cutaneous T cell lymphoma that involves the oral mucosal. The manifestation of lesions within the oral cavity generally correlates with a poor prognosis. Management of MF includes skin directed therapies and localized radiation treatment, with systemic biologic therapies and chemotherapy used for more advanced stages. Read More

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August 2017
3 Reads

Reactive lesions of oral cavity: A retrospective study of 659 cases.

J Indian Soc Periodontol 2017 Jul-Aug;21(4):258-263

Department of Oral and Maxillofacial Pathology and Microbiology, SDM College of Dental Sciences and Hospital, Dharwad, Karnataka, India.

Objective: This study reviews, analyzes, and compares the demographic data, histopathological features and discusses the treatment and prognosis of reactive lesions (RLs).

Materials And Methods: Retrospective study was performed on the departmental archives from July 2006 to July 2016 (total 5000 cases) comprising of 659 cases of RLs of the oral cavity. The recorded data included age, gender, size, site, duration, habits, etiology, histopathological diagnosis, treatment, and prognosis. Read More

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http://dx.doi.org/10.4103/jisp.jisp_103_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813338PMC
February 2018
5 Reads

Reactive hyperplastic lesions of the oral cavity: A retrospective survey study and literature review.

Indian J Dent Res 2018 Jan-Feb;29(1):61-66

Department of Community Dentistry, MIDSR Dental College, Latur, India.

Context: The reactive lesions are relatively common in the oral cavity because of the frequency with which the tissues are injured. They often result from a known stimulus or injury such as dental plaque, calculus, or foreign material.

Aims: : The aim of this study was to review the clinicopathologic features of reactive hyperplastic lesions (RHLs) of the oral cavity at MIDSR, Dental College and Hospital, Latur, Maharashtra, and to compare these data with those of previously reported studies. Read More

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http://dx.doi.org/10.4103/ijdr.IJDR_599_16DOI Listing
September 2018
4 Reads

A Case Series of Fibro-Osseous Lesions of the Jaws.

Kobe J Med Sci 2017 Dec 18;63(3):E73-E79. Epub 2017 Dec 18.

Department of Oral and Maxillofacial Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.

The aim of this case series was to reveal the difficulties in diagnosing fibro-osseous lesions with radiological and histopathological examinations and quantify the potential risk of infection to fibro-osseous legions. To analyze the concordance between radiological and histopathological diagnoses, this retrospective case series included patients who were clinically diagnosed with fibro-osseous lesions via radiological findings and excluded the patients who did not undergo histopathological examinations. This study also included the patients in whom histopathological results confirmed fibro-osseous legions when preoperative radiological diagnosis did not include fibro-osseous legions. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826023PMC
December 2017
2 Reads

Giant-cell fibroma: Understanding the nature of the melanin-laden cells.

J Oral Maxillofac Pathol 2017 Sep-Dec;21(3):429-433

Department of Oral Pathology, Manipal College of Dental Sciences, Manipal, Karnataka, India.

Giant-cell fibroma is a localized, benign fibrous mucosal mass, which clinically mimics any other fibroepithelial growth, and its distinction from other lesions is on the basis of its peculiar histopathology. A case of giant-cell fibroma with stroma strewn with brown pigment-laden cells is presented herewith. Immunohistochemical staining aided with histochemical reaction to understand the origin of these cells was carried out. Read More

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http://dx.doi.org/10.4103/jomfp.JOMFP_209_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763868PMC
February 2018
1 Read

Osteopontin expression and clinicopathologic correlation of oral hyperplastic reactive lesions: An institutional 6-year retrospective study.

J Oral Maxillofac Pathol 2017 Sep-Dec;21(3):382-386

Department of Periodontics, Post Graduate Institute of Dental Sciences, Pt. B.D. Sharma University of Health Sciences, Rohtak, Haryana, India.

Background And Objective: Reactive proliferations of oral cavity comprise pyogenic granuloma (PG), fibrous hyperplasia (FH), peripheral ossifying fibroma (POF), and peripheral giant-cell granuloma (PGCG). They often pose diagnostic challenges due to their overlapping clinical and histopathological features. This study was conducted to determine the frequency and clinicopathological correlation of reactive hyperplastic lesions in the oral cavity reported in our institute and compared it with other previous studies. Read More

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http://dx.doi.org/10.4103/jomfp.JOMFP_231_15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5763860PMC
February 2018
3 Reads

Paediatric oral pathology in Thailand: a 15-year retrospective review from a medical teaching hospital.

Int Dent J 2018 Aug 28;68(4):227-234. Epub 2018 Jan 28.

Department of Pathology, Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok, Thailand.

Objectives: To determine whether the spectrum of oral pathology in children seen at a medical institution differs from studies derived from dental facilities.

Methods: Oral biopsy records from paediatric patients (<16 years of age) were retrieved from the pathology archives at Chulalongkorn University Hospital over a period of 15 years. Lesions were categorised as inflammatory/reactive, tumour/tumour-like or cystic. Read More

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http://dx.doi.org/10.1111/idj.12380DOI Listing
August 2018
3 Reads

Granular cell tumors of the tongue: fibroma or schwannoma.

Head Face Med 2018 Jan 3;14(1). Epub 2018 Jan 3.

Department of Oral and Maxillofacial Surgery, Plastic Surgery, Gunma University Graduate School of Medicine, Gunma, Japan.

Background: Granular cell tumors are benign lesions that typically occur in the oral cavity, but can also be found in other sites. However, the characteristics of these tumors are unclear. Thus, the present study aimed to investigate the immunohistological characteristics of these tumors of the tongue. Read More

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http://dx.doi.org/10.1186/s13005-017-0158-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5795288PMC
January 2018
3 Reads

Fibroma-like PEComa: A Tuberous Sclerosis Complex-related Lesion.

Am J Surg Pathol 2018 Apr;42(4):500-505

Departments of Pathology.

Perivascular epithelioid cell tumor (PEComa), mesenchymal tumors morphologically characterized by epithelioid cells, coexpress melanocytic and muscle markers. Herein, we describe a heretofore-undescribed tuberous sclerosis complex (TSC)-related neoplasm, morphologically resembling a soft tissue fibroma-like lesion, but showing an immunophenotype resembling PEComa. We identified 3 soft tissue fibroma-like lesions in individuals with TSC. Read More

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http://Insights.ovid.com/crossref?an=00000478-201804000-0000
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http://dx.doi.org/10.1097/PAS.0000000000001024DOI Listing
April 2018
8 Reads
5.140 Impact Factor

Prospective study of the 532 nm laser (KTP) versus diode laser 980 nm in the resection of hyperplastic lesions of the oral cavity.

Med Oral Patol Oral Cir Bucal 2018 Jan 1;23(1):e78-e85. Epub 2018 Jan 1.

Dental School - University of Seville C/ Avicena s/n 41009 Sevilla, SPAIN,

Background: The aim of this study is to evaluate the resection of hyperplastic lesions on the buccal mucosa comparing the 532nm laser (KTP), versus diode 980nm laser, considering pain, scarring, inflammation and drug consumption that occurred postoperatively with each lasers.

Material And Methods: A prospective study of consecutive series of 20 patients in two groups that presents hyperplastic lesions on the buccal mucosa. The choice of the KTP laser or diode 980nm laser for the surgery was made randomly. Read More

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http://dx.doi.org/10.4317/medoral.21812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5822545PMC
January 2018
5 Reads

Ameloblastic Fibro-odontoma with a Predominant Radiopaque Component.

Ann Maxillofac Surg 2017 Jul-Dec;7(2):304-307

Department of Oral and Maxillofacial Surgery, Sri Rajiv Gandhi College of Dental Sciences and Hospital, Bengaluru, Karnataka, India.

Ameloblastic fibro-odontoma (AFO) is a rare odontogenic tumor. Initially believed to be a lesion similar to ameloblastic fibroma (AF), it is now considered as a separate entity in the WHO odontogenic tumor classification. Commonly associated with a painless swelling and an associated absence of eruption of a tooth, AFO presents as a mixed radiopaque and radiolucent lesion in the younger population with a predilection for the posterior region. Read More

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http://dx.doi.org/10.4103/ams.ams_84_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717913PMC
December 2017
6 Reads