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    1809 results match your criteria Oral Fibromas and Fibromatoses

    1 OF 37

    Clinicopathologic and Molecular Characteristics of Familial Cherubism with Associated Odontogenic Tumorous Proliferations.
    Head Neck Pathol 2017 Jul 18. Epub 2017 Jul 18.
    Division of Oral and Maxillofacial Pathology, School of Dentistry, University of Minnesota, 515 Delaware Street SE 16-206B, Minneapolis, MN, 55455, USA.
    Cherubism is a rare autosomal dominant condition affecting the jaws and caused by mutations in the gene encoding for the adapter protein SH3BP2 that maps to chromosome 4p16.3. Cherubism is characterized by symmetrically developing bone lesions in the maxilla and mandible. Read More

    Ameloblastic Fibrodentinoma: A Case with Varied Patterns of Dysplastic Dentin.
    Cureus 2017 Jun 14;9(6):e1349. Epub 2017 Jun 14.
    Department of Oral and Maxillofacial Pathology, Krishnadevaraya College of Dental Sciences and Hospital.
    Ameloblastic fibrodentinoma is a benign odontogenic tumor belonging to the category of "odontogenic epithelium with odontogenic ectomesenchyme" along with recognition of induction in the form of dentin in atypical or dysplastic forms. The biological behaviour of ameloblastic fibrodentinoma is not very different from ameloblastic fibroma; hence, it is treated similarly by conservative procedures. It is important to understand the histopathogenesis of these rare tumors. Read More

    Ultrasound imaging of oral fibroma: a case report.
    J Biol Regul Homeost Agents 2017 Apr-Jun;31(2 Suppl 1):23-26
    Multidisciplinary Department of Medical and Dental Specialties, University of Campania- Luigi Vanvitelli, Naples, Italy.
    Oral mucosa is constantly under the influence of various internal and external stimuli, therefore it is interested by a range of developmental disorders, irritation, inflammation, and neoplastic conditions. Traumatic fibroma is one of these lesions. The aim of this work is to obtain an ultrasound characterization of a lip fibroma with a high frequency probe (8-18 MHz) as feasibility and experimental model of this non-invasive technique in the oral mucosa compared with its histo-pathological section. Read More

    The role of Osterix protein in the pathogenesis of peripheral ossifying fibroma.
    Braz Oral Res 2017 Jul 3;31:e53. Epub 2017 Jul 3.
    Universidade Estadual Paulista - Unesp, Science and Technology Institute, Department of Bioscience and Oral Diagnosis, São José dos Campos, SP, Brazil.
    Peripheral ossifying fibroma (POF) is a reactive lesion of oral tissues, associated with local factors such as trauma or presence of dental biofilm. POF treatment consists of curettage of the lesion combined with root scaling of adjacent teeth and/or removal of other sources of irritants. This study aimed to analyze the clinical and pathological features of POF and to investigate the immunoexpression of Osterix and STRO-1 proteins. Read More

    New tumour entities in the 4th edition of the World Health Organization Classification of Head and Neck tumours: odontogenic and maxillofacial bone tumours.
    Virchows Arch 2017 Jul 3. Epub 2017 Jul 3.
    Department of Oral & Maxillofacial Pathobiology, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.
    The latest (4th) edition of the World Health Organization Classification of Head and Neck tumours has recently been published with a number of significant changes across all tumour sites. In particular, there has been a major attempt to simplify classifications and to use defining criteria which can be used globally in all situations, avoiding wherever possible the use of complex molecular techniques which may not be affordable or widely available. This review summarises the changes in Chapter 8: Odontogenic and maxillofacial bone lesions. Read More

    Costal graft as a support for bone regeneration after mandibular juvenile ossifying fibroma resection: An unusual case report.
    J Stomatol Oral Maxillofac Surg 2017 Jun 19. Epub 2017 Jun 19.
    Service de stomatologie et chirurgie maxillo-faciale, CHU de Nantes, 1, place Alexis-Ricordeau, 44093 Nantes cedex 1, France. Electronic address:
    Spontaneous regeneration of bone tissue after mandibular resection is rare in adults, although it does often take place in children. Periosteum conservation appears to play a major role in this healing process. We here report regarding a 5-year-old boy who exhibited a large mandibular trabecular juvenile ossifying fibroma. Read More

    Conglomeration of Trabecular and Psammomatoid variants of juvenile ossifying fibroma - a rare case report.
    Clin Case Rep 2017 Jun 17;5(6):816-821. Epub 2017 Apr 17.
    Department of Oral and Maxillofacial PathologyKalinga Institute of Dental SciencesKIITBhubaneswarOdishaIndia.
    Juvenile ossifying fibroma is an uncommon benign fibro-osseous lesion occurring in the craniofacial skeleton with a high recurrence rate. It has two distinct histopathologic variants: one trabecular and the other which are exclusive to each other. This case reveals a rare and unique combination of both the patterns in the same lesion. Read More

    Trabecular Variant: A Rare Entity of Juvenile Ossifying Fibroma of the Mandible.
    Contemp Clin Dent 2017 Jan-Mar;8(1):179-181
    Department of Oral Medicine and Radiology, National Institute of Medical Sciences Dental College and Hospital, Jaipur, Rajasthan, India.
    One of the rarest entities of fibro-osseous lesions that arise within the craniofacial bones is Juvenile ossifying fibroma (JOF). It is an intraosseous expansile lesion of the jaw that imitate odontogenic lesions. WHO has described two distinct histopathological variants of JOF; trabecular and psammomatoid. Read More

    A case of primordial odontogenic tumor: A new entity in the latest WHO classification (2017).
    Pathol Int 2017 Jul 25;67(7):365-369. Epub 2017 May 25.
    Department of Oral and Maxillofacial Pathobiology, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
    Primordial odontogenic tumor (POT) is a rare lesion in the jaw which has been included as a new entity of benign mixed epithelial and mesenchymal odontogenic tumour in the latest World Health Organization (WHO) classification (2017). Only seven cases have been reported. It typically occurs in the posterior mandible. Read More

    Differential diagnosis of periapical cyst using collagen birefringence pattern of the cyst wall.
    Restor Dent Endod 2017 May 9;42(2):111-117. Epub 2017 Feb 9.
    Department of Conservative Dentistry, Gangneung-Wonju National University College of Dentistry, Gangneung, Korea.
    Objectives: Periapical lesions, including periapical cyst (PC), periapical granuloma (PG), and periapical abscess (PA), are frequently affected by chemical/physical damage during root canal treatment or severe bacterial infection, and thus, the differential diagnosis of periapical lesions may be difficult due to the presence of severe inflammatory reaction. The aim of this study was to make differential diagnosis among PC, PG, and PA under polarizing microscope.

    Materials And Methods: The collagen birefringence patterns of 319 cases of PC (n = 122), PG (n = 158), and PA (n = 39) obtained using a polarizing microscope were compared. Read More

    Metastasis of a Renal Collecting Duct Adenocarcinoma to the Oral Cavity After Tooth Extraction.
    J Craniofac Surg 2017 Jun;28(4):e398-e399
    *Department of Pathology, Faculty of Medicine †Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Gaziantep University, Gaziantep ‡Department of Pathology, Faculty of Medicine, TOBB Economics and Technology, Ankara, Turkey.
    Metastatic tumors rarely occur in the oral cavity. The most common of the oral metastases are lung cancers in males, and breast and genital cancers in females. The most common primary tumor metastasis to the oral cavity is from the lung, kidney, liver, prostate, and colorectal cancers. Read More

    Assessment of reactive gingival lesions of oral cavity: A histopathological study.
    J Oral Maxillofac Pathol 2017 Jan-Apr;21(1):180
    Department of Oral and Maxillofacial Pathology, Navodaya Dental College, Raichur, Karnataka, India.
    Background: In the literature, many studies were attempted to analyze the distribution of oral reactive lesions in terms of age, gender and location. However, very few studies have focused on the detailed histopathological features of these reactive lesions of oral cavity. Thus, the purpose of this paper is to document the occurrence, distribution and various histopathological features of reactive gingival lesions. Read More

    Concurrent central odontogenic fibroma and dentigerous cyst in the maxilla: A rare case report.
    J Oral Maxillofac Pathol 2017 Jan-Apr;21(1):149-153
    Department of Oral Pathology, Rajarajeswari Dental College and Hospital, Bengaluru, Karnataka, India.
    Central odontogenic fibroma (COF) represents a rare group of benign odontogenic tumor, while dentigerous cyst (DC), on the other hand, is the odontogenic cyst that encloses the crown of an unerupted tooth. A combination of COF and DC is rare and not reported in literature till date. The aim of this paper is to report a case of COF occurring concurrently with DC. Read More

    Intraoral neurilemmoma of mental nerve mimicking as traumatic fibroma: An unusual presentation - A case report and literature review.
    J Oral Maxillofac Pathol 2017 Jan-Apr;21(1):124-128
    Department of Oral and Maxillofacial Pathology, Faculty of Dental Sciences, Sri Ramachandra Medical Centre, Chennai, Tamil Nadu, India.
    Neurilemmoma, neurinoma or schwannoma is a benign tumor of neurogenic origin, arising from the myelin sheath of a neuron. Head and neck region accounts for 25%-48% of these tumors reported till date. On the contrary, intraoral sites form only 1% of the cases accounted. Read More

    Surgical Treatment of a Peripheral Ossifying Fibroma and Reconstruction with a Porcine Collagen Matrix: A Case Report.
    Int J Periodontics Restorative Dent 2017 May/Jun;37(3):443-449
    A 35-year-old woman was referred to the Department of Oral Medicine and Orofacial Surgery after several recurrences of an ossifying fibroma (OF) that affected the free and attached gingiva of the maxillary right central incisor. Surgery was performed with a complete excision of the lesion together with the surrounding healthy tissue up to the bone. To guide the healing of the anterior esthetic framework and the excised tissues, a porcine collagen matrix as an alternative to connective tissue graft was used. Read More

    Oral diseases: a 14-year experience of a Chilean institution with a systematic review from eight countries.
    Med Oral Patol Oral Cir Bucal 2017 May 1;22(3):e297-e306. Epub 2017 May 1.
    University of Talca, Lircay Av. S/N, Talca, Chile, Zip code 3460000,
    Background: Retrospective studies to assess the distribution of oral diseases (ODs) are helpful in estimating the prevalence of oral diagnoses in the population, and thus help in preventive and curative services. Prevalence and frequency data for ODs are available from many countries, but information from Chile is scarce.

    Material And Methods: This study investigated the frequency of OD in a Chilean population. Read More

    Desmoplastic Fibroma of the Mandible in a Pediatric Patient: A Case Report of Resection and Reconstruction With A Six-Year Follow-Up.
    J Oral Maxillofac Surg 2017 Jul 14;75(7):1568.e1-1568.e10. Epub 2017 Mar 14.
    Observer, Department of Surgical Oncology and Maxillofacial Surgery, Faculty of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile.
    Desmoplastic fibroma (DF) of bone is considered a benign but locally aggressive tumor of fibroblastic origin. DF is rare, representing less than 1% of all bone tumors. Approximately 84% of patients are younger than 30 years. Read More

    Peripheral Odontogenic Fibroma: A Rare Tumor mimicking a Gingival Reactive Lesion.
    Int J Clin Pediatr Dent 2017 Jan-Mar;10(1):103-106. Epub 2017 Feb 27.
    Private Practitioner, Dr. Khot's Dental Clinic, Mumbai, Maharashtra, India.
    Gingival growths are one of the most frequently encountered lesions in the oral cavity. A plethora of lesions can be seen having similar clinical presentation, making diagnosis a dilemma. Peripheral odontogenic tumors are rare neoplasms to occur on gingiva, the most common among them being the peripheral odontogenic fibroma (POdF). Read More

    Pediatric Palatal Fibroma.
    Int J Clin Pediatr Dent 2017 Jan-Mar;10(1):96-98. Epub 2017 Feb 27.
    Professor, Department of Oral and Maxillofacial Surgery, Purvanchal Institute of Dental Sciences, Gorakhpur, Uttar Pradesh, India.
    Fibroma is one of the most common soft tissue benign tumors of the oral cavity. These masses represent hyperplasias instead of true neoplasm, which develop due to irritation to the mucosal tissue resulting in proliferation of the cells. Although so common in the oral cavity, its occurrence on the palate is rare, mainly due to fewer chances of trauma. Read More

    Intraosseous Venous Malformations of the Zygoma: Report of 4 Cases and Literature Review.
    Ann Otol Rhinol Laryngol 2017 Jun 4;126(6):505-509. Epub 2017 Apr 4.
    1 Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, P.R. China.
    Objectives: As intraosseous venous malformations (IVMs) of the zygoma are very rare and clinical features are not typical, a correct preoperative diagnosis may be difficult to make. This study presents 4 cases of IVM of the zygoma and gives a review of their clinical manifestations, radiographic features, preoperative diagnosis, and differentials.

    Methods: The report of 4 cases was performed with an average 6-year follow-up. Read More

    Minimally Invasive Excision of Epulides with a CO2 Laser: A Retrospective Study of 90 Patients.
    Photomed Laser Surg 2017 Mar 30. Epub 2017 Mar 30.
    3 IMAH, Institute of Morphological Analytics and Human Genetics , Graz, Austria .
    Objective: It is the aim of this study to evaluate if the CO2 laser can beneficially be applied for excising epulides.

    Background Data: The standard procedure for treating epulides involves the excision of the hyperplastic tissue followed in most cases by the removal of parts of the underlying bone and the final closure of the wound by a flap. The use of the CO2 laser for the treatment of epulides has been documented only in isolated case reports and very few case series. Read More

    [Chondromyxoid fibroma of the mandible: a case report].
    Hua Xi Kou Qiang Yi Xue Za Zhi 2016 Dec;34(6):654-656
    Dept. of Oral and Maxillofacial Surgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China.
    Chondromyxoid fibroma (CMF) is a rare benign bone tumor. This tumor mostly affects the long bones of the appendicular skeleton but rarely grows in the craniofacial region. In this article, a case of CMF of the mandible was presented to enhance our understanding of CMF. Read More

    A comparative study of syndecan-1 expression in different odontogenic tumors.
    J Oral Biol Craniofac Res 2017 Jan-Apr;7(1):23-26. Epub 2016 Nov 10.
    Dental Research Center, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
    Background: Expression of various cellular/molecular factors change during the course of tumor formation from odontogenic tissues of the tooth germ. Evaluation of these factors can help provide a better perception of the tumorigenesis and biologic behavior of odontogenic tumors (OTs). Syndecan-1 is a heparan sulfate proteoglycan which has not been extensively investigated in these lesions. Read More

    Unusually large-sized peripheral ossifying fibroma.
    Ann Maxillofac Surg 2016 Jul-Dec;6(2):300-303
    Department of Oral and Maxillofacial Surgery, Vinayaka Mission's Sankarachariyar Dental College and Hospital, Salem, Tamil Nadu, India.
    Fibrous growths in the gingiva with the histopathological presence of calcifications are a common occurrence in the oral cavity. These lesions can be neoplastic in nature with either odontogenic or non odontogenic origin or they can be reactive lesions. This is a case report of an unusual presentation of peripheral ossifying fibroma , unusual because of its abnormally large size with review of literature. Read More

    Psammomatoid Juvenile Ossifying Fibroma of Mandible in a 41-Year Male Patient.
    J Coll Physicians Surg Pak 2017 Jan;27(1):49-50
    Department of Oral and Maxillofacial Pathology, NIMS Dental College, NIMS University, Shobha Nagar, Jaipur, India.
    Juvenile ossifying fibroma (JOF) is a rare fibro-osseous neoplasm that develops among the craniofacial bones at an early age; and in majority of patients, it is diagnosed in the first or second decade of life. We present a case in 41-year male patient having it in the left anterior mandibular region. Peripheral eosinophilic areas resembling psammomatoid bodies along with other features impelled the diagnosis of psammomatoid ossifying fibroma. Read More

    Mandibular Reconstruction by Using a Liquid Nitrogen-Treated Autograft in a Dog with an Oral Tumor.
    J Am Anim Hosp Assoc 2017 May/Jun;53(3):167-171. Epub 2017 Mar 14.
    From the Cooperative Department of Veterinary Medicine, Faculty of agriculture, Iwate University, Morioka, Japan (Y.O., J.S., M.G., M.K., Y.U.); the United Graduate School of Veterinary Sciences, Gifu University, Gifu, Japan (K.H.); Department of Veterinary Medicine, Faculty of Agriculture, University of Tokyo, Tokyo, Japan (T.M.); and the Department of Orthopaedic Surgery and Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan (H.N., H.T.).
    A 10 yr old intact female German shepherd dog presented with a large peripheral odontogenic fibroma and malignant melanoma on her lower jaw. The tumor was resected with a unilateral subtotal rostral hemimandibulectomy. After the mandible was removed, it was devitalized intraoperatively by freezing it in liquid nitrogen. Read More

    Desmoplastic Fibroblastoma in Maxillary Alveolar Bone Mimicking An Odontogenic Lesion: A Novel Case Report with Review of Literature.
    Turk Patoloji Derg 2017 Feb 4. Epub 2017 Feb 4.
    Department of Oral and Maxillofacial Pathology, Shiraz Dental School, Shiraz University of Medical Sciences, Shiraz, Iran.
    Desmoplastic fibroblastoma (Collagenous fibroma) is a rare benign soft tissue tumor that disseminates widely and can be intramuscular or subcutaneously. There are seven reported cases in the oral cavity so far. We reported a novel case of collagenous fibroma that has been found in the anterior part of maxilla in a 58-year-old woman as an intraosseous radiolucent lesion that has been discovered during routine radiography. Read More

    Oral mucosal lesions in a Chilean elderly population: A retrospective study with a systematic review from thirteen countries.
    J Clin Exp Dent 2017 Feb 1;9(2):e276-e283. Epub 2017 Feb 1.
    Gerontology Program, Faculty of Medical Sciences, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.
    Background: The oral examination is an essential part of the multidisciplinary medical care in elderly people. Oral mucosal lesions and normal variations of oral anatomy (OMLs) are very common in this people, but few studies have examined the frequency and prevalence of these conditions worldwide and less in Chile. The aim of this research was to evaluate the frequency of OMLs in a Chilean elderly population. Read More

    Juvenile Trabecular Ossifying Fibroma of the Maxilla: a Case Report.
    Med Arch 2016 Dec;70(6):470-472
    Department of Oral Pathology and Diagnosis, Faculty of Dentistry, Lebanese University, Beirut, Lebanon.
    Introduction: Juvenile ossifying fibromas are uncommon benign tumors. Their aggressiveness added to their high tendency to recur, provoke real diagnostic and therapeutic challenges for the dental practitioner and make a postoperative follow-up over the years indispensable.

    Case Report: In this report, we present a case of a seven-year-old girl presented with a swelling in the face at the upper right maxillary region. Read More

    Histological evaluation of the possible transformation of peripheral giant cell granuloma and peripheral ossifying fibroma: A preliminary study.
    Indian J Pathol Microbiol 2017 Jan-Mar;60(1):15-20
    Department of Pathology, Gülhane Military Medical Academy, Ankara, Turkey.
    Aims: The objective of this study is to describe shared morphological features of peripheral giant cell granuloma (PGCG) and peripheral ossifying fibroma (POF) in detail and discuss the possible relationship between them.

    Materials And Methods: Ten intermediate cases with features resembling to both POF and PGCG were selected and type 3 and 1 collagen immunostainings were performed for evaluation of the connective tissue maturation. Immunohistochemical staining percentage (SP) for stromal cells in the slides of POF and PGCG counterparts of intermediate lesions was scored as 1 when the SP was above 10%, 2 when the SP was above 25%, 3 when the SP was above 50% and 4 when the SP was above 75%. Read More

    Ameloblastic fibroodontoma or complex odontoma: Two faces of the same coin.
    Natl J Maxillofac Surg 2016 Jan-Jun;7(1):92-95
    Department of Oral and Maxillofacial Pathology, King Georges Medical University, Lucknow, Uttar Pradesh, India.
    An ameloblastic fibroodontoma (AFO) is a rare odontogenic tumor of mixed dental tissue origin. It exhibits histological features of ameloblastic fibroma and complex odontoma. AFOs are usually found to be asymptomatic and are most often discovered on routine radiography. Read More

    Successful treatment of tumour-induced osteomalacia after resection of an oral peripheral ossifying fibroma.
    BMJ Case Rep 2017 Jan 24;2017. Epub 2017 Jan 24.
    Department of Radiology, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines.
    Tumour-induced osteomalacia is a paraneoplastic syndrome wherein bone is affected by a hormone from a tumour that causes renal phosphate wasting and hypophosphataemia. Here, we present the case of a 31-year-old man who has been suffering from generalised bone pains and a spine deformity that led to loss of height. Pertinent findings are low serum phosphorus, low vitamin D and decreased bone mineral density. Read More

    An Unusually Large Irritation Fibroma Associated with Gingiva of Lower Left Posterior Teeth Region.
    Case Rep Dent 2016 28;2016:5202181. Epub 2016 Dec 28.
    Department of Oral Medicine and Radiology, Swargiya Dadasaheb Kalmegh Smruti Dental College & Hospital, Nagpur, India.
    Fibroma is a benign tumor of oral cavity, with usually the tongue, gingiva, and buccal mucosa being the most common sites. Females are twice more likely to develop fibroma than males. The intraoral fibroma typically is well demarcated; and its size can vary from millimeter to few centimeters. Read More

    The "Drawer-Like" Resection and Reconstruction With Titanium Mesh: A Novel Surgical Technique for Treatment of Giant Ossifying Fibroma in the Maxilla.
    J Oral Maxillofac Surg 2016 Dec 29. Epub 2016 Dec 29.
    Professor, Department of Oral Maxillofacial-Head Neck Oncology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, China. Electronic address:
    Purpose: The aim of this article is to introduce a new surgical method for the treatment of ossifying fibroma (OF) in the maxilla with dislocation of the eyeball and to evaluate the postoperative outcomes and prognosis.

    Patients And Methods: Cases of maxillary OF treated with "drawer-like" resection from 2014 to 2015 were reviewed. The surgical procedure consisted of total removal of the orbital floor and most of the maxilla with preservation of the alveolar ridge immediately followed by reconstruction with titanium mesh. Read More

    Fibrous Dysplasia versus Juvenile Ossifying Fibroma: A Dilemma.
    Case Rep Dent 2016 22;2016:6439026. Epub 2016 Dec 22.
    Department of Oral Medicine and Radiology, AJ Institute of Dental Sciences, Mangalore, Karnataka, India.
    Fibrous dysplasia (FD) is a condition characterized by excessive proliferation of bone forming mesenchymal cells which can affect one bone (monostotic type) or multiple bones (polyostotic type). It is predominantly noticed in adolescents and young adults. Fibrous dysplasia affecting the jaws is an uncommon condition. Read More

    Evaluation of mast cell counts and microvessel density in reactive lesions of the oral cavity.
    J Dent Res Dent Clin Dent Prospects 2016 21;10(4):241-246. Epub 2016 Dec 21.
    Postgraduate Student, Biotechnology Research Center and Department of Orthodontics, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
    Background. Reliable immunohistochemical assays to assess the definitive role of mast cells (MCs) and angiogenesis in the pathogenesis of oral reactive lesions are generally not available. The aim of the present study was to evaluate mast cell counts (MCC) and microvessel density (MVD) in oral reactive lesions and determine the correlation between MCC and MVD. Read More

    MMP-1 and MMP-8 expression in giant-cell fibroma and inflammatory fibrous hyperplasia.
    Pathol Res Pract 2016 Dec 15;212(12):1108-1112. Epub 2016 Oct 15.
    Pontifícia Universidade Católica do Paraná, School of Health and Biosciences, Rua Imaculada Conceição, 1155, Prado Velho 80.215-901, Curitiba, PR, Brazil. Electronic address:
    The aim of this study is to compare the immunoexpression of metalloproteinases 1 and 8 in giant-cell fibroma, inflammatory fibrous hyperplasia and normal mucosa. Twenty-two cases of giant-cell fibroma, inflammatory fibrous hyperplasia and oral mucosa (control) each were subjected to immunohistochemistry using anti-metalloproteinase-1 and anti-metalloproteinase-8 antibodies. Eight images of each case were captured and analysed through the a) application of a count grid to count the number of positive neutrophils, macrophages, lymphocytes, plasma cells, fibroblasts and blood vessels to obtain the percentage of staining and b) semi-automated segmentation quantifying the stained area in square micrometres. Read More

    Can Differences in Vascularity Serve as a Diagnostic Aid in Fibro-Osseous Lesions of the Jaws?
    J Oral Maxillofac Surg 2017 Jun 24;75(6):1201-1208. Epub 2016 Nov 24.
    Head of Oral Pathology Service, Institute of Pathology, Rabin Medical Center, Petach-Tikva; Head of Oral Pathology Service, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel. Clinical Professor, Department of Oral Pathology and Medicine, Goldschleger School of Dental Medicine, and Clinical Professor, Department of Pathology, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
    Purpose: Different lesions in the fibro-osseous group share microscopic features; thus, establishing a definitive diagnosis based on microscopic features alone can be a challenge. There is a need for additional microscopic tools to aid in differentiating these lesions. This study compared parameters related to vascularity among 3 lesions in the fibro-osseous group: fibrous dysplasia (FD), central ossifying fibroma (COF), and cemento-osseous dysplasia (COD). Read More

    Odontogenic myxofibroma of gingiva in a pediatric patient with tuberous sclerosis: A rare case report.
    Contemp Clin Dent 2016 Oct-Dec;7(4):558-561
    Department of Oral Medicine and Radiology, Maulana Azad Institute of Dental Sciences, New Delhi, India.
    Tuberous sclerosis complex (TSC) is a rare multisystem genetic disease, with an estimated incidence of 1 in 6000-1 in 10,000. TSC is an autosomal dominant syndrome involving heart, kidneys, lungs, and skin. The classic triad of TSC is seizures, mental retardation, and angiofibromas; this triad occurs in only 29% of patients. Read More

    Peripheral Ameloblastic Fibroma: Report of a Rare Case.
    J Dent (Shiraz) 2016 Dec;17(4):367-369
    Postgraduate Student, Dept. of Orthodontics, School of Dentistry, Kerman Oral and Dental Diseases Research Center, Kerman, Iran.
    Ameloblastic fibroma is a rare mixed odontogenic tumor mostly occurring in the posterior region of the mandible. The peripheral variant is very rare and to the best of our knowledge, only three cases have been reported in the English literature. In this report, we describe a case of peripheral ameloblastic fibroma in a 54-year-old woman with two years of follow-up. Read More

    Challenges in Evaluating the Severity of Fibropapillomatosis: A Proposal for Objective Index and Score System for Green Sea Turtles (Chelonia mydas) in Brazil.
    PLoS One 2016 9;11(12):e0167632. Epub 2016 Dec 9.
    Research Group on Fibropapillomatosis in Sea Turtles, University of São Paulo, São Paulo/SP, Brazil.
    Fibropapillomatosis (FP) is a neoplastic disease that affects marine turtles worldwide, especially green sea turtles (Chelonia mydas). FP tumors can develop on the body surface of marine turtles and also internally in the oral cavity and viscera. Depending on their quantity, size and anatomical distribution, these tumors can interfere with hydrodynamics and the ability to feed, hence scoring systems have been proposed in an attempt to quantify the clinical manifestation of FP. Read More

    Coverage Root after Removing Peripheral Ossifying Fibroma: 5-Year Follow-Up Case Report.
    Case Rep Dent 2016 7;2016:6874235. Epub 2016 Nov 7.
    Department of Oral Pathology, São Leopoldo Mandic Institute and Research Center, Campinas, SP, Brazil.
    When lesions in soft tissue reach the gingival margin, they can produce aesthetic defects during its permanence and after its removal. Periodontal plastic surgery allows the correction of the gingival contour using different techniques. This paper is a case report of a peripheral ossifying fibroma removal in the interproximal area of teeth 21 and 22 in addition to root coverage of the affected area through two surgical phases: keratinized gingival tissue augmentation surgery with free gingival graft concurrent with removal of the lesion and, in a second stage, root coverage by performing coronally advanced flap technique with a follow-up of five years. Read More

    Iodine-125 Interstitial Brachytherapy for Pediatric Desmoid-Type Fibromatosis of the Head and Neck: A Case Report.
    J Oral Maxillofac Surg 2017 Apr 29;75(4):768.e1-768.e11. Epub 2016 Oct 29.
    Professor, Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing, China. Electronic address:
    Desmoid-type fibromatosis (DF) is a locally aggressive benign soft tissue tumor. It is rarely observed in the head and neck region and is particularly uncommon in the parotid gland. This report describes the case of a 32-month-old girl with DF of the head and neck. Read More

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