2,083 results match your criteria Oral Fibromas and Fibromatoses

Developing complex odontoma in a 4-year-old child with active ameloblastic follicles: A case report.

J Oral Maxillofac Pathol 2021 Mar 19;25(Suppl 1):S84-S89. Epub 2021 Mar 19.

Dr Paulose Dental Clinic and Maxillofacial Centre, Salem, Tamil Nadu, India.

The World Health Organization (WHO) classification of odontogenic tumors, in its different iterations, has seen several modifications in benign mixed odontogenic tumors. Odontoma is a benign mixed odontogenic tumor that shows dental hard tissue formation to varying degrees. Although odontomas are the most common odontogenic tumors, they are mostly seen in the form of compound odontomas, where the dental hard tissues resemble tooth-like structures. Read More

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Concurrent dentigerous cyst with ossifying fibroma of the mandible.

J Oral Maxillofac Pathol 2021 Mar 19;25(Suppl 1):S68-S70. Epub 2021 Mar 19.

Department of Oral Pathology, Dental Institute, RIMS, Ranchi, Jharkhand, India.

Dentigerous cyst (DC) and ossifying fibroma (OF) are intraosseous lesions of the jaw. Both are varied pathological entities with a wide spectrum of clinical and histological features along with distinct treatment plan and prognosis. While OF comes under fibro-osseous lesions of the jaws, DC is a developmental odontogenic cyst which is formed by the accumulation of fluid between reduced enamel epithelium and enamel or between layers of the enamel organ. Read More

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Cemento-Ossifying Fibroma of Upper Lip in a Female Child.

Cureus 2021 Apr 26;13(4):e14692. Epub 2021 Apr 26.

Oral and Maxillofacial Pathology, Thai Moogambigai Dental College and Hospital, Chennai, IND.

Cemento-ossifying fibroma (COF) is a benign tumor classified under fibro-osseous lesions characterized by the proliferation of fibrous tissue associated with the presence of osteoid or cementicle-like masses. COF of bony origin is highly neoplastic in nature compared to their soft tissue counterparts which are relatively rare. The authors here present a case report of COF arising from the left upper lip in a 10-year-old female patient. Read More

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Central odontogenic fibroma of simple type: An original observation.

SAGE Open Med Case Rep 2021 28;9:2050313X211012494. Epub 2021 Apr 28.

Department of Oral Medicine and Oral Surgery, SAHLOUL Hospital (Sousse), Dental Faculty of Monastir, University of Monastir, Sousse, Tunisia.

Central odontogenic fibroma is an uncommon, benign, slow-growing intraosseous mesenchymal odontogenic tumour. It presents a diagnostic dilemma to the clinician and the pathologist because its clinical and radiological features resemble other odontogenic and/or non-odontogenic tumours, and the differential diagnosis is based on histological examination. In this report, we describe our experience with a case of a 23-year-old female patient with central odontogenic fibroma of the mandible that was diagnosed as 'simple type'. Read More

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A Rare Case of Peripheral Ossifying Fibroma in an Infant.

Contemp Clin Dent 2021 Jan-Mar;12(1):81-83. Epub 2021 Mar 20.

Department of Oral Medicine and Radiology, Maulana Azad Institute of Dental Sciences, New Delhi, India.

Peripheral ossifying fibroma (POF) associated with natal/neonatal teeth is extremely rare. In general, POF occurs as a soft-tissue gingival nodule occurring in young adults. We report an unusual and a rare case in a 5-month-old male child who had two, localized, soft-tissue growth over the mandibular anterior alveolar ridge. Read More

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Cemento-Ossifying Fibroma in Maxillofacial Region: A Series of 16 Cases.

J Maxillofac Oral Surg 2021 Jun 8;20(2):240-245. Epub 2019 Nov 8.

Department of Oral and Maxillofacial Surgery, Sri Guru Ram Das Institute of Dental Sciences and Research, Mall Mandi, GT Road, Amritsar, 143001 India.

Introduction: Cemento-ossifying fibroma is considered as a benign osseous tumour, closely related to other lesions such as fibrous dysplasia and cementifying periapical dysplasia. These lesions occur in the second to the fourth decade of life. It is a bony tumour of maxilla and mandible of possibly odontogenic origin with aggressive behaviour and high tendency for recurrence. Read More

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Sialolithiasis of minor salivary gland: a challenging diagnostic dilemma.

J Korean Assoc Oral Maxillofac Surg 2021 Apr;47(2):145-148

Department of Oral and Maxillofacial Surgery, School of Dentistry, University of Athens, Athens, Greece.

Minor salivary gland sialolithiasis (MSGS) is a not uncommon oral mucosal disease. Its clinical appearance may mimic a mucocyst or other benign submucosal overgrowth. Stasis of saliva, which accompanies MSGS, usually results in minor salivary gland inflammation, with a chronic sialadenitis appearance. Read More

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Large myxomatous odontogenic tumor in the jaw: a case series.

J Korean Assoc Oral Maxillofac Surg 2021 Apr;47(2):112-119

Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea.

Objectives: Myxomatous odontogenic tumors (MOTs) are the third most common odontogenic tumors in the oral and maxillofacial region. Due to its slow-growing, but locally invasive nature, the tumor is usually detected by accident or only when it becomes a large mass, which causes facial deformity.

Materials And Methods: Current study reports three unusual cases of MOT including huge myxoma involve the mandible in middle-aged man, MOT with ossifying fibroma pattern in mandible, and MOT in maxilla of young female patient. Read More

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Neurofibromatosis Type 1 With Cherubism-like Phenotype, Multiple Osteolytic Bone Lesions of Lower Extremities, and Alagille-syndrome: Case Report With Literature Survey.

In Vivo 2021 May-Jun;35(3):1711-1736

Institute of Human Genetics, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.

Background/aim: Neurofibromatosis type 1 (NF) is an autosomal dominant hereditary disease. The cardinal clinical findings include characteristic skeletal alterations. Difficulties in diagnosis and therapy can arise if an individual has further illnesses. Read More

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February 2021

An analysis of the prevalence of peripheral giant cell granuloma and pyogenic granuloma in relation to a dental implant.

BMC Oral Health 2021 04 23;21(1):204. Epub 2021 Apr 23.

Department of Odontoestomatology, Faculty of Medicine and Health Sciences (Dentistry), Bellvitge Campus, University of Barcelona, Barcelona, Spain.

Background: The aim of the present investigation was to evaluate the literature recurrence of peripheral giant cell granuloma and pyogenic granuloma associated with dental implants. It's important to know the characteristics present in these lesions and possible effects on the prognosis of dental implants.

Methods: An electronic search without time restrictions was done in the databases: PubMed/Medline. Read More

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Large irritation fibroma of hard palate: a case report of a rare clinical entity.

Pan Afr Med J 2021 19;38:61. Epub 2021 Jan 19.

Department of Otorhinolaryngology, Giannitsa General Hospital, Pella, Greece.

Fibromas are benign tumors of connective tissue common in the oral cavity but rare on hard palate. This paper reports on an asymptomatic, slowly growing mass on the hard palate of a 90-year-old lady, with a reported use of denture for two decades. The patient presented with a 2. Read More

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The importance of clinical and radiological findings for the definitive histopathologic diagnosis of benign fibro-osseous lesions of the jaws: Study of 276 cases.

J Stomatol Oral Maxillofac Surg 2021 Apr 18. Epub 2021 Apr 18.

Istanbul University, Institute of Oncology, Department of Tumour Pathology, Istanbul, Turkey.

Purpose: Benign fibro-osseous lesions (BFOLs) are heterogeneous intraosseous disease processes sharing overlapping histopathologic features and demonstrate a wide range of biological behavior. The aim of this study is to highlight the importance of clinical and radiological findings for the definitive histopathologic diagnosis of benign fibro-osseous lesions of the jaws.

Materials And Methods: This is a cross-sectional retrospective study evaluating the three main groups of BFOLs: Cemento-osseous dysplasia, ossifying fibromas, and fibrous dysplasia. Read More

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Ameloblastic fibrosarcoma of the maxilla with EGFR exon 20 insertions: Relevance of whole-exome sequencing in molecular understanding and therapeutic proposals for rare cancers.

Auris Nasus Larynx 2021 Apr 15. Epub 2021 Apr 15.

Department of Diagnostic Pathology, Kyoto University Hospital, 54 Shogoin Kawahara-cho, Kyoto 606-8507, Japan.

Ameloblastic fibrosarcoma (AFS) is the most common odontogenic sarcoma, but the incidence is relatively low, and its molecular biology is poorly understood. We experienced a young female patient with a rapidly growing soft tissue tumor of the left maxilla, which eventually occupied the left side of the oral cavity. Histologically, the tumor mainly consisted of a proliferation of atypical spindle to polygonal cells without any specific differentiation, but a small number of benign odontogenic epithelial foci mainly in the tumor periphery were also noted; thus, a diagnosis of AFS was made. Read More

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18F-FDG PET/CT in the Hyperparathyroidism-Jaw-Tumor Syndrome.

Clin Nucl Med 2021 06;46(6):497-498

From the Division of Nuclear Medicine, Department of Radiology.

Abstract: Hyperparathyroidism-jaw-tumor syndrome (HPT-JTS) is a rare autosomal dominant disorder. A typical manifestation of HPT-JTS is the association of jaw-ossifying fibroma with primary hyperparathyroidism. Due to its rarity and diversity in its manifestations, it is a challenging diagnosis. Read More

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Enucleation of Recurrent Central Odontogenic Fibroma and Bone Regeneration of the Osseous Defect with Enamel Matrix Derivative and Bone Allograft: Case Report with 5-year Follow-up.

Jonathan H Do

Clin Adv Periodontics 2021 Mar 27. Epub 2021 Mar 27.

Section of Periodontics, UCLA School of Dentistry, Los Angeles, California.

Introduction: Odontogenic fibroma is a rare benign neoplasm of mature fibrous connective tissue with variable amounts of inactive-looking odontogenic epithelium. Few recurrences of central odontogenic fibroma (COF) have been reported in the literature. This manuscript reports the enucleation of a recurrent COF and bone regeneration of the osseous defect with enamel matrix derivative and bone allograft. Read More

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Histochemical characterization of bone and cementum using modified gallego's iron fuschin stain and van gieson stain and its application in fibro-osseous lesions.

Indian J Dent Res 2020 Nov-Dec;31(6):888-892

Department of Oral Pathology, Government Dental College and Hospital, Aurangabad, Maharashtra, India.

Objectives: Fibro-osseous lesions (FOLs) of the jaws exhibit an overlapping histomorphologic spectrum with respect to nature of calcifications. Sometimes these calcifications may be difficult to characterize as bone and cementum on routine Hematoxylin and Eosin (H&E) staining. This causes difficulty in assessing the origin and diagnosis of these lesions. Read More

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Juvenile Psammomatoid Cemeto-ossifying Fibroma of Mandible: a Diagnostic dilemma.

BMJ Case Rep 2021 Mar 19;14(3). Epub 2021 Mar 19.

Dentistry-Oral & Maxillofacial Surgey, All India Institute of Medical Sciences-Raipur, Raipur, Tatibandh, India.

Psammomatoid Juvenile ossifying fibroma (PsJOF) is a rare benign fibro-osseous lesion characterised to grow to unusually large size very rapidly. Its usual presentation is in younger age group mostly children and predominately involving the Sino-Naso-Orbital region. Its aggressive nature gimmicks a malignant lesion but it is rather a benign lesion with a higher recurrence rate than the conventional ossifying fibroma but lacking metastatic potential. Read More

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Calcifying epithelial odontogenic tumor: a case series spanning 25 years and review of the literature.

Oral Surg Oral Med Oral Pathol Oral Radiol 2021 Jun 9;131(6):684-693. Epub 2021 Jan 9.

Program Director, Oral & Maxillofacial Pathology, Department of Oral and Maxillofacial Diagnostic Sciences, University of Florida College of Dentistry.

Objective: The calcifying epithelial odontogenic tumor (CEOT) is a rare benign neoplasm that makes up less than 1% of all odontogenic tumors. This study aims to describe a case series of CEOT spanning 25 years and to review and compare our results with the existing literature.

Study Design: With institutional review board approval, all CEOT archival cases from the University of Florida Oral Pathology Biopsy Service between 1994 and 2019 were retrieved. Read More

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Review of Pediatric Head and Neck Neoplasms that Raise the Possibility of a Cancer Predisposition Syndrome.

Head Neck Pathol 2021 Mar 15;15(1):16-24. Epub 2021 Mar 15.

Department of Pathology, Texas Childrens Hospital, 6621 Fannin St, Houston, TX, 77030, USA.

Cancer predisposition syndromes (CPS) are generally heritable conditions that predispose individuals to develop cancer at a higher rate and younger age than their representative general population. They are a significant cause of cancer related morbidity and mortality in the pediatric population. Therefore, recognition of lesions that may be associated with a CPS and alerting the clinicians to its implications is a crucial task for a diagnostic pathologist. Read More

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Odontogenic and Developmental Oral Lesions in Pediatric Patients.

Head Neck Pathol 2021 Mar 15;15(1):71-84. Epub 2021 Mar 15.

Academic Unit of Oral and Maxillofacial Medicine and Pathology, School of Clinical Dentistry, University of Sheffield, Sheffield, UK.

This article reviews odontogenic and developmental oral lesions encountered in the gnathic region of pediatric patients. The process of odontogenesis is discussed as it is essential to understanding the pathogenesis of odontogenic tumors. The clinical presentation, microscopic features, and prognosis are addressed for odontogenic lesions in the neonate (dental lamina cysts/gingival cysts of the newborn, congenital (granular cell) epulis of the newborn, melanotic neuroectodermal tumor, choristoma/heterotopia, cysts of foregut origin), lesions associated with unerupted/erupting teeth (hyperplastic dental follicle, eruption cyst, dentigerous cyst, odontogenic keratocyst/keratocystic odonogenic tumor, buccal bifurcation cyst/inflammatory collateral cyst) and pediatric odontogenic hamartomas and tumors (odontoma, ameloblastic fibroma, ameloblastoma, adenomatoid odontogenic tumor, primordial odontogenic tumor). Read More

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Gingival Fibroma: An Emerging Distinct Gingival Lesion with Well-Defined Histopathology.

Head Neck Pathol 2021 Mar 8. Epub 2021 Mar 8.

Department of Oral and Maxillofacial Diagnostic Services, University of Florida College of Dentistry, 1395 Center Dr, Gainesville, FL, 32610-0414, USA.

Gingival growths, barring a few are mostly reactive and seldom exhibit significant true neoplastic potential. The common etiology is local irritation from dental plaque/calculus, trauma as well as medication-related overgrowth. Such lesions are easily distinguishable and categorized into diagnoses such as pyogenic granuloma, peripheral ossifying fibroma, etc. Read More

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Identification of elastofibroma and elastofibroma-like lesions in cases diagnosed as oral fibromas.

Biotech Histochem 2021 Feb 19:1-8. Epub 2021 Feb 19.

Department of Morphology, Federal University of Rio Grande Do Norte, Natal, RN, Brazil.

We investigated elastofibromas (EF) and elastofibroma-like structures (EFL) in 95 cases that had been diagnosed as oral fibromas (OF). Histological sections were stained with Verhoeff-Van Gieson, Congo red and hematoxylin and eosin to enable possible reclassification to EF or EFL, or to retain the diagnosis of OF. To do this, we identified amyloid and used histopathological descriptions and epidemiological clinical profiles. Read More

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February 2021

Ameloblastic Fibroma in Mandibular Anterior Tooth Region: A Case Report.

Bull Tokyo Dent Coll 2021 Mar 15;62(1):49-54. Epub 2021 Feb 15.

Department of Oral and Maxillofacial Surgery, Tokyo Dental College.

An ameloblastic fibroma (AF) is a proliferative mixed tumor which includes components of both odontogenic epithelium and mesenchymal tissue. It is a relatively rare neoplasm, accounting for approximately only 1.5-4. Read More

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Classification and nomenclature of fibro-osseous lesions.

Oral Surg Oral Med Oral Pathol Oral Radiol 2021 Apr 29;131(4):385-389. Epub 2021 Jan 29.

Professor and Chair, Oral & Maxillofacial Radiology, Department of Oral, Biological and Medical Sciences, The University of British Columbia, Vancouver, BC, Canada.

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Surgical resection of a giant peripheral ossifying fibroma in mouth floor managed with fiberscopic intubation.

Clin Case Rep 2021 Jan 6;9(1):180-184. Epub 2020 Nov 6.

Department of Oral and Maxillofacial Surgery Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama Japan.

Tracheal intubation for general anesthesia can sometimes be difficult in patients with a large mass in the mouth floor. Preoperative evaluation of the patient's airway is most important when treating large oral disease. Read More

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January 2021

Oral giant cell fibroma: A report of three cases.

J Dent Sci 2021 Jan 14;16(1):552-554. Epub 2020 Sep 14.

Department of Dentistry, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.

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January 2021

Central ossifying fibroma of mandible.

BMJ Case Rep 2020 Dec 28;13(12). Epub 2020 Dec 28.

Department of Radiodiagnosis, Krishna Institute of Medical Sciences Deemed University, Karad, Maharashtra, India.

Ossifying fibroma (OF) is a rare, benign, fibro-osseous lesion of the jawbone characterised by replacement of the normal bone with fibrous tissue. The fibrous tissue shows varying amount of calcified structures resembling bone and/or cementum. The central variant of OF is rare, and shows predilection for mandible among the jawbone. Read More

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December 2020

SATB2 is not a reliable diagnostic marker for distinguishing between oral osteosarcoma and fibro-osseous lesions of the jaws.

Oral Surg Oral Med Oral Pathol Oral Radiol 2021 May 4;131(5):572-581. Epub 2020 Nov 4.

Department of Pathology, Rambam Medical Center, Haifa, Israel; The Ruth and Bruce Rappaport Faculty of Medicine, Haifa, Israel.

Objective: Special AT-rich binding protein 2 (SATB2) is an immunohistochemical marker for osteoblast differentiation. Our aim was to investigate SATB2 expression in oral osteosarcoma and other bone-producing oral tumors/reactive lesions to evaluate its usefulness as a diagnostic marker.

Study Design: A total of 74 intraosseous and soft tissue bone-producing surgical samples and 10 samples of reactive bone tissue were stained with SATB2, including osteosarcoma/chondrosarcoma (n = 16), fibro-osseous lesions (n = 42), central giant cell granuloma (n = 6), osteoblastoma (n = 1), and gingival lesions (n = 9). Read More

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Desmoplastic fibroma of the jaw bones: A series of twenty-two cases.

J Bone Oncol 2021 Feb 21;26:100333. Epub 2020 Oct 21.

TOBB ETU School of Medicine, Department of Pathology, Beştepe, Yaşam Cd. No:5, 06560 Yenimahalle, Ankara, Turkey.

Desmoplastic fibroma (DF) is an intraosseous counterpart of desmoid-type soft tissue fibromatosis. It is most frequently seen in the jawbones. The clinical and radiological features of the present cases were nonspecific. Read More

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February 2021

[Clinical application and accuracy analysis of occlusion-guided functional mandibular reconstruction].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2020 Nov;34(11):1410-1416

Department of Oral and Maxillofacial Surgery, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou Zhejiang, 310003, P.R.China.

Objective: To investigate the influence of the design and application of novel surgical template on the accuracy of reconstructed mandibula and implant position in occlusion-guided functional mandibular reconstruction, so as to provide guidance for clinical treatment.

Methods: Between January 2017 and May 2019, 11 patients with segmental mandible defects were treated, including 8 males and 3 females with an average age of 31.8 years (range, 19-45 years). Read More

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November 2020