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    Predictive value of p63, ki-67, and survivin expression in oral leukoplakia: A tissue microarray study.
    Microsc Res Tech 2017 Mar 27. Epub 2017 Mar 27.
    Oral Pathology, School of Dentistry, Universidade Federal do Rio Grande do Sul, Brazil.
    The aim of this study was to analyze the immunohistochemical expression of survivin, ki-67, and p63 in oral leukoplakic lesions, histopathologically differentiated into dysplastic and nondysplastic. A tissue microarray containing 57 samples of biopsies from clinically classified lesions, such as leukoplakia, was immunolabeled for survivin, ki-67, and p63. Samples were scored for percentage of positively stained. Read More

    Nasal, oral, and pharyngolaryngeal manifestations of pemphigus vulgaris: Endoscopic ororhinolaryngologic examination.
    Ear Nose Throat J 2017 Mar;96(3):120-127
    Department of Otolaryngology, Saitama Medical Center, Saitama Medical University, 1981 Kamoda, Kawagoe-shi, Saitama 350-8550, Japan.
    Pemphigus vulgaris is an autoimmune blistering disorder that involves the skin and mucous membranes. Few reports have described nasal and oropharyngolaryngeal lesions in pemphigus vulgaris using an endoscopic ororhinolaryngologic examination. We retrospectively reviewed the clinical records of 11 patients with pemphigus vulgaris between 2001 and 2013 with respect to their symptoms, lesion sites, lesion features, and treatments received. Read More

    The Balloon-Based Manometry Evaluation of Swallowing in Patients with Amyotrophic Lateral Sclerosis.
    Int J Mol Sci 2017 Mar 27;18(4). Epub 2017 Mar 27.
    Ear, Nose & Throat (ENT) Department, Faculty of Medicine, Jagiellonian University Medical College, Kraków 31-531, Poland.
    The aim of the study was to analyse the disturbances of the oro-pharyngeal swallowing phase of dysphagia in amyotrophic lateral sclerosis (ALS) patients with the use of specific manometric measurements and to evaluate their plausible association with the duration of the disease. Seventeen patients with ALS were evaluated with manometric examinations of the oral and pharyngeal part of the gastrointestinal tract. Tests were carried out by using the oesophageal balloon-based method with four balloon transducers located 5 cm away from each other. Read More

    Day Surgery for Acute Appendicitis in Adults: A Prospective Series of 102 Patients.
    Surg Laparosc Endosc Percutan Tech 2017 Mar 24. Epub 2017 Mar 24.
    *Department of General and Digestive Surgery, Hôpital Saint Antoine (AP-HP), Paris VI University †Department of General and Digestive Surgery, Hôpital Kremlin-Bicetre (AP-HP), Paris XI University, Paris, France.
    Aim: To report the results of a consecutive series of day surgery appendectomy (DSA) for acute appendicitis.

    Methods: Selection criteria for DSA were as follows: body mass index<28 kg/m, white cell count <15,000/mL, C-reactive protein<30 mg/L, no radiological signs of perforation, and appendix diameter ≤10 mm. All patients with radiologically proven appendicitis and 4 or 5 criteria were proposed for DSA and prospectively included. Read More

    Personal and occupational risk factors for carpal tunnel syndrome in meat processing industry workers in Northern Italy.
    Med Pr 2017 Mar 15;68(2):199-209. Epub 2017 Mar 15.
    University of Parma, Parma, Italy (Department of Biomedical, Biotechnological and Translational Sciences).
    Background: Carpal tunnel syndrome (CTS) is a musculoskeletal condition that often impairs the fitness to work. Our aim is to retrospectively evaluate the association between physical exposures in meat processing industry in Northern Italy and the CTS, taking into account non-occupational factors.

    Material And Methods: A cross-sectional study was performed to include 434 workers (236 males, 198 females, 37. Read More

    Use of First-phase Insulin Secretion in Early Diagnosis of Thyroid Diabetes and Type 2 Diabetes Mellitus.
    Chin Med J (Engl) 2017 Apr;130(7):798-804
    Department of Endocrine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China.
    Background: A relationship between hyperthyroidism and insulin secretion in type 2 diabetes mellitus (T2DM) has been reported. Therefore, this study explored the use of first-phase insulin secretion in the differential diagnosis of thyroid diabetes (TDM) and T2DM.

    Methods: In total, 101 patients with hyperthyroidism were divided into hyperthyroidism with normal glucose tolerance (TNGT), hyperthyroidism with impaired glucose regulation (TIGR), and diabetes (TDM) groups. Read More

    Does a social/behavioural gradient in dental health exist among adults? A cross-sectional study.
    J Int Med Res 2017 Jan 1:300060516675682. Epub 2017 Jan 1.
    1 Depertment of Surgical, Microsurgical and Medical Sciences, University of Sassari, Sassari, Italy.
    Objective To explore the potential presence of a social/behavioural gradient in dental health among Italian adults using a cross-sectional study. Methods Caries indices were recorded among 480 subjects (52.9% men, 47. Read More

    Systemic Lupus Erythematosus and hearing disorders: Literature review and meta-analysis of clinical and temporal bone findings.
    J Int Med Res 2017 Jan 1:300060516688600. Epub 2017 Jan 1.
    2 Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, Italy.
    Objective This literature review and meta-analysis was performed to evaluate the correlations among hearing and vestibular clinical symptoms, temporal bone findings, and pathological mechanisms in patients with systemic lupus erythematosus (SLE). Study design Relevant papers in the literature were retrospectively reviewed. Clinical hearing aspects in patients with SLE and relevant temporal bone studies in the same field were analyzed. Read More

    VEGFR-3 Expression in Oral Lichen Planus
    Asian Pac J Cancer Prev 2017 02 1;18(2):381-384. Epub 2017 Feb 1.
    Oral and Maxillofacial Pathology Department, Dental Faculty, Babol University of Medical Sciences, Babol, Iran.
    Background and objective: Given the postulated the role of inflammation and possible contribution of lymphangiogenesis in oral lichen planus, this study aimed to assess any associated presence of VEGFR-3. Material and Methods: This cross-sectional study was performed on 52 formalin fixed and paraffin embedded blocks of oral lichen planus (pathological diagnosis based on Modified WHO criteria), comprising 25 of erosive and 27 of reticular type, along with 60 samples of normal mucosa (with minimal inflammation from clinical and histopathological aspects) obtained at crown lengthening surgery. Four micron sections were cut from paraffin blocks and stained with H and E for confirmation of diagnosis and by immunohistochemistry with primary antibodies against VEGFR-3. Read More

    Relationship of Lifetime Exposure to Tobacco, Alcohol and Second Hand Tobacco Smoke with Upper aero-digestive tract cancers in India: a Case-Control Study with a Life-Course Perspective
    Asian Pac J Cancer Prev 2017 02 1;18(2):347-356. Epub 2017 Feb 1.
    School of Dentistry and Oral Health, Griffith University, Gold Coast, Australia.
    Background: Squamous cell carcinomas of the upper aero-digestive tract (UADTSCC) are a multifaceted public health problem. Effects of lifestyle risk factors, including tobacco (chewing and smoking), alcohol drinking and exposure to second hand tobacco smoke (SHS) at home and their association with UADT cancers was assessed in a case-control study with a life-course perspective. The study was conducted at two different hospitals in Pune, India. Read More

    Patient-Linked Factors Associated with Delayed Reporting of Oral and Pharyngeal Carcinoma among Patients Attending National Cancer Institute, Maharagama, Sri Lanka
    Asian Pac J Cancer Prev 2017 02 1;18(2):321-325. Epub 2017 Feb 1.
    Dental Surgeon, Oral Cancer Department, National Cancer Control Programme, Ministry of Health, Sri Lanka.
    Background: Diagnosis of cancer at an early stage improves prognosis following treatment. Unfortunately a large proportion of oral and pharyngeal cancer patients are diagnosed at late stages which require radical treatment with considerable morbidity and mortality. Many researchers have examined different types of delay that could occur between the onset of symptoms and diagnosis. Read More

    Palatal Radicular Groove Morphology of the Maxillary Incisors: A Case Series Report.
    J Endod 2017 Mar 23. Epub 2017 Mar 23.
    State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu, China. Electronic address:
    Introduction: Teeth with a palatal radicular groove are challenging to diagnose, treat, and save. We classified this condition using cone-beam computed tomographic (CBCT) cross-sectional configurations combined with radiographic and morphologic observations during an intentional replantation procedure to identify and analyze the characteristics of palatal radicular grooves comprehensively as a reference for diagnosis, treatment planning, and prognosis evaluation of this condition.

    Methods: Eight cases with palatal radicular grooves present in permanent maxillary incisors were investigated by radiography and CBCT imaging before intentional replantation. Read More

    The influence of general health on the need for dental general anaesthesia in children.
    Eur Arch Paediatr Dent 2017 Mar 25. Epub 2017 Mar 25.
    Department of Cariology, Endodontology and Paediatric Dentistry, Research Unit of Oral Health Sciences, University of Oulu, P.O. Box 5281, 90014, Oulu, Finland.
    Aim: To analyse the occurrence and causes of dental general anaesthesia (DGA) in healthy and medically compromised children, and to investigate if there are differences between those groups considering factors associated with DGA and DGA procedures.

    Methods: The data was collected from medical records of children under 7 years of age treated under DGA in the years 2009 and 2010 at the Oulu University Hospital, Finland. The children were divided into two groups: 0-35-month-olds and ≥36-month olds. Read More

    [Malignant cutaneous adnexal neoplasms of the face and scalp: Diagnostic and therapeutic update].
    J Stomatol Oral Maxillofac Surg 2017 Mar 22. Epub 2017 Mar 22.
    Service de stomatologie, chirurgie maxillo-faciale et plastique, hôpital Nord, centre hospitalier des Bourrely, 13015 Marseille, France.
    Introduction: Malignant cutaneous adnexal neoplasms are rare and have been characterized only recently. They can occur at any age but preferentially in elderly. There are 3 of them: trichoblastic carcinoma, trichilemmal carcinoma and malignant pilomatricoma. Read More

    PDGFRA mRNA is overexpressed in oral cancer patients as compared to normal subjects with a significant trend of overexpression among tobacco users.
    J Oral Pathol Med 2017 Mar 25. Epub 2017 Mar 25.
    Department of Oral and Maxillofacial-Head & Neck Oncology, Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, No. 639, Zhi Zao Ju Road, Shanghai, 200011, China.
    Background: Platelet derived growth factors alpha (PDGFA) is a tyrosine kinase receptor activator which known to be amplified in the malignancies and their expression levels are correlated to tumor progression and reduced overall survival. The expression of PDGFRA is different among the tumors and normal tissues, furthermore; their expression level is site-specific. Under a physiological condition, PDGFRA and its ligand are expressed in distinct cell populations and activated in a paracrine manner. Read More

    Glycogen-Rich Clear Cell Squamous Cell Carcinoma Originating in the Oral Cavity.
    Head Neck Pathol 2017 Mar 24. Epub 2017 Mar 24.
    Department of Oncology and Diagnostic Sciences, School of Dentistry, University of Maryland Baltimore, 650 West Baltimore Street, 7th Floor North, Baltimore, MD, 21201, USA.
    Clear cell squamous cell carcinoma (CCSCC) is a rare histological subtype of squamous cell carcinoma (SCC) that was originally described in the skin. Here, we report a case of a 66-year-old female patient who presented with a fungating ulcerative mass of the left lateral tongue extending anteriorly to the floor of the mouth, and posteriorly to the left retromolar fossa and the oropharynx. The patient had a history of SCC of the left posterior tongue that was treated with partial glossectomy and adjuvant radiotherapy. Read More

    Long-term skeletal and dental effects of facemask versus chincup treatment in Class III patients : A retrospective study.
    J Orofac Orthop 2017 Mar 24. Epub 2017 Mar 24.
    Institute of Software Development and Biomedical Engineering, Technical University Graz, Graz, Austria.
    Objectives: To investigate the skeletal and dental changes during chincup versus facemask treatment, to compare the long-term effects of the two appliances, and to document the impact of each on treatment success.

    Methods: In all, 61 patients with Class III syndrome were retrospectively analyzed at three examination times: 7.8 ± 1. Read More

    Conservative Treatment with Octreotide to Provide Early Recovery of Children with Esophageal Perforation.
    Thorac Cardiovasc Surg 2017 Mar 24. Epub 2017 Mar 24.
    Gazi University Medical Faculty, Department of Pediatric Surgery, Besevler, Ankara, Turkey.
    Background The effectiveness of nonoperative treatment of esophageal perforation (EP) in children with octreotide is highlighted. Methods Records of nine patients (seven boys and two girls with an average age of 5.83 ± 5. Read More

    New horizons in hospital acquired pneumonia in older people.
    Age Ageing 2017 Feb 27:1-7. Epub 2017 Feb 27.
    Newcastle University, Institute of Cellular Medicine, Newcastle upon Tyne, Tyne and Wear , United Kingdom.
    Approximately 1.5% of hospital patients develop hospital acquired pneumonia. Aspiration is the major risk factor for pneumonia and is associated with reduced ability to mechanically clear respiratory pathogens into the stomach. Read More

    J Matern Fetal Neonatal Med 2017 Mar 24:1-19. Epub 2017 Mar 24.
    c Department of Obstetrics and Gynecology , Erciyes University Faculty of Medicine , Kayseri , Turkey.
    Background: The objective of this study was to identify the gestational diabetes mellitus (GDM) prevalence difference according to American Diabetes Association (ADA) criteria and International Association of Diabetes and Pregnancy Study Group (IADPSG) criteria for 75 g oral glucose tolerance test (OGTT).

    Methods: This study was conducted at Erciyes University Department of Obstetrics and Gynecology. A total of 320 pregnant who met the criteria were included in the study and 75 g OGTT was applied. Read More

    Helicobacter pylori in periodontal pockets and saliva: a possible role in gastric infection relapses.
    J Biol Regul Homeost Agents 2017 Jan-Mar;31(1):257-262
    Department of Medicine and Surgery, University of Insubria, ASST dei Sette Laghi, Unit of Gastroenterology.
    It has been a long time since the scientific community started to speculate upon the presence of Helicobacter pylori (HP) in periodontal pockets as an extra-gastric reservoir responsible for gastric relapses after eradication therapy. The aim of this study is to evaluate the presence of oral HP in a group of patients who underwent examination for gastric infection. Sixty patients were enrolled in the current study, subdivided into two groups: 30 patients with a positive result for HP gastric infection with C-Breath Test Urea examination, and 30 patients with a negative result for HP gastric infection. Read More

    Current update on the diagnosis and management of head and neck hard tissue sarcomas.
    J Oral Pathol Med 2017 Mar 24. Epub 2017 Mar 24.
    Department of Oral and Maxillofacial Surgery, Queen Alexandra Hospital, Portsmouth, UK.
    Head and neck hard tissue sarcomas form a rare group of mesenchymal derived tumours that comprise less than 1% of all head and neck neoplasms. Hard tissue sarcomas account for 20% of head and neck sarcomas and they form a heterogeneous group with a diverse origin. Unlike head and neck soft tissue sarcomas, they have lower recurrence and mortality rates. Read More

    The role of fluoride and chlorhexidine in preserving hardness and mineralization of enamel and cementum after gamma irradiation.
    Radiat Environ Biophys 2017 Mar 23. Epub 2017 Mar 23.
    Health Radiation Research Department, National Center for Radiation Research and Technology (NCRRT), Atomic Energy Authority, Cairo, Egypt.
    The purpose of this study was to evaluate the effect of 0.05% sodium fluoride and 0.12% chlorhexidine mouthwashes on the micro-hardness of tooth enamel and cementum that was exposed to therapeutic doses of gamma radiation. Read More

    Osteonecrosis of the Femoral Head in an Adolescent on Long-Term Inhalational Corticosteroids.
    Case Rep Pediatr 2017 28;2017:6969787. Epub 2017 Feb 28.
    Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, OH, USA.
    A relationship between the development of osteonecrosis of the femoral head and systemic corticosteroids has been well established in the literature, particularly in adults. However, the link between osteonecrosis and inhaled corticosteroids is less researched and understood. We report an usual case report of a 10-year-old male who developed ipsilateral femoral head osteonecrosis after long-term inhalational corticosteroid and intermittent short courses of oral steroid usage with a unique presentation and delayed diagnosis. Read More

    Revisiting Cementoblastoma with a Rare Case Presentation.
    Case Rep Pathol 2017 26;2017:8248691. Epub 2017 Feb 26.
    Department of Oral Pathology and Microbiology, Faculty of Dental Sciences, Sri Ramachandra University, Chennai, India.
    Cementoblastoma is a rare benign odontogenic neoplasm which is characterized by the proliferation of cellular cementum. Diagnosis of cementoblastoma is challenging because of its protracted clinical, radiographic features, and bland histological appearance; most often cementoblastoma is often confused with other cementum and bone originated lesions. The aim of this article is to overview/revisit, approach the diagnosis of cementoblastoma, and also present a unique radiographic appearance of a cementoblastoma lesion associated with an impacted tooth. Read More

    Effect of Transplantation of Bone Marrow Derived Mesenchymal Stem Cells and Platelets Rich Plasma on Experimental Model of Radiation Induced Oral Mucosal Injury in Albino Rats.
    Int J Dent 2017 26;2017:8634540. Epub 2017 Feb 26.
    Radiation Oncology, National Cancer Institute, Cairo University, Giza, Egypt.
    Normal tissue damage following radiotherapy is still a major problem in cancer treatment. Therefore, the current work aimed at exploring the possible role of systemically injected bone marrow derived mesenchymal stem cells (BM-MSCs) and/or locally injected platelet rich plasma (PRP) in ameliorating the side effects of ionizing radiation on the rat's tongue. Twelve rats served as control group (N) and 48 rats received a single radiation dose of 13 Gy to the head and neck region; then, they were equally divided into 4 experimental groups: irradiated only (C), irradiated + MSCs (S), irradiated + (PRP) (P), and combined group (PS). Read More

    A case series of trigeminal nerve injuries caused by periapical lesions of mandibular teeth.
    Br Dent J 2017 Mar;222(6):447-455
    King's College London Dental Institute, Oral Surgery, Denmark Hill Campus, Bessemer Road, London, SE5 9RS.
    Aims Periapical lesions have been implicated in mandibular trigeminal sensory neuropathy. This study aimed to report on a case series of consecutive patients presenting with mandibular division trigeminal nerve injuries (TNI) caused by periapical lesions. Common presenting characteristics and possible strategies for management were also investigated. Read More

    The Word Heart Federation Roadmap for Nonvalvular Atrial Fibrillation.
    Glob Heart 2017 Mar 20. Epub 2017 Mar 20.
    Department of Cardiac Sciences, Cumming School of Medicine, Division of Cardiology, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada; Alberta Health Services, Foothills Medical Centre, Calgary, Alberta, Canada.
    Background: The World Heart Federation has undertaken an initiative to develop a series of Roadmaps to promote development of national policies and health systems approaches, and to identify potential roadblocks on the road to effective prevention, detection, and management of cardiovascular disease in low-and middle-income countries (LMICs) and develop strategies for overcoming these. This Roadmap focuses on atrial fibrillation (AF). AF is the most common, clinically significant arrhythmia and, among other clinical outcomes, is associated with increased risk of stroke. Read More

    Oral Cancer Awareness Among Dental Patients in Omdurman, Sudan: a cross-sectional Study.
    BMC Oral Health 2017 Mar 23;17(1):69. Epub 2017 Mar 23.
    Faculty of Dentistry, University of Science and Technology, Omdurman, Sudan.
    Background: Oral cancer is a preventable disease. Its occurrence is mostly due to lifestyle. In Sudan, the use of smokeless tobacco (Toombak) has long been linked to oral cancer. Read More

    Is Accessibility to Dental Care Facilities in Rural Areas Associated with Number of Teeth in Elderly Residents?
    Int J Environ Res Public Health 2017 Mar 21;14(3). Epub 2017 Mar 21.
    Department of Functional Pathology, Shimane University School of Medicine, 89-1 Enya-cho, Izumo, Shimane 693-8501, Japan.
    Given that public transportation networks are less developed in rural than in urban areas, a lack of accessibility to dental care facilities could be a barrier to routine dental checkups. Thus, we hypothesized that the distance to the dental care facilities is a risk factor for tooth loss. The aim of this study was to test whether there is an association between the distance to dental care facilities, estimated by geographic information systems, and number of teeth, assessed by an oral examination, among elderly residents of a rural area in Japan. Read More

    An Examination of the Role of L-Glutamate and Inosine 5'-Monophosphate in Hedonic Taste-Guided Behavior by Mice Lacking the T1R1 + T1R3 Receptor.
    Chem Senses 2017 Mar 17. Epub 2017 Mar 17.
    Department of Psychology and Program in Neuroscience, Florida State University, Tallahassee, FL, USA.
    The heterodimeric T1R1 + T1R3 receptor is considered critical for normal signaling of L-glutamate and 5'-ribonucleotides in the oral cavity. However, some taste-guided responsiveness remains in mice lacking one subunit of the receptor, suggesting that other receptors are sufficient to support some behaviors. Here, mice lacking both receptor subunits (KO) and wild-type (WT, both n = 13) mice were tested in a battery of behavioral tests. Read More

    Benchmarking Outcomes in Implant Prosthodontics: Partial Fixed Dental Prostheses and Crowns Supported by Implants with a Turned Surface over 10 to 28 Years at the University of Toronto.
    Int J Oral Maxillofac Implants 2017 Mar 23. Epub 2017 Mar 23.
    Purpose: The aim of this noninterventional, retrospective study was to benchmark the outcomes of patients with partial fixed prostheses supported by implants treated at the University of Toronto at least 10 years earlier. A study protocol for assessing outcomes on like patients developed at the University of Bern, Switzerland, was followed.

    Materials And Methods: All patients who had received at least one implant before 2002 were considered eligible to be included in the study (n = 298). Read More

    Esthetic and Patient-Centered Outcomes of Single Implants: A Retrospective Study.
    Int J Oral Maxillofac Implants 2017 Mar 23. Epub 2017 Mar 23.
    Purpose: The aims of this clinical study were to retrospectively evaluate implant survival, patient satisfaction, and radiographic, clinical, and esthetic outcomes following single-implant treatment.

    Materials And Methods: Eighty-seven patients, with a total of 126 implants (XiVE S, Dentsply Implants), who received single implant-retained crowns between 2004 and 2011 were retrospectively evaluated. Implant survival, marginal bone levels (MBL), changes in implant/mesial tooth vertical relationship, pink esthetic score (PES), white esthetic score (WES), patient assessment of the esthetics (visual analog scale), and oral health impact profile (OHIP-14) were evaluated. Read More

    Adjuvant treatment with the bacterial lysate (OM-85) improves management of atopic dermatitis: A randomized study.
    PLoS One 2017 23;12(3):e0161555. Epub 2017 Mar 23.
    Assistance Publique-Hôpitaux de Paris, Hôpital Necker-Enfants Malades, Department of Dermatology, Paris, France.
    Background: Environmental factors play a major role on atopic dermatitis (AD) which shows a constant rise in prevalence in western countries over the last decades. The Hygiene Hypothesis suggesting an inverse relationship between incidence of infections and the increase in atopic diseases in these countries, is one of the working hypothesis proposed to explain this trend.

    Objective: This study tested the efficacy and safety of oral administration of the bacterial lysate OM-85 (Broncho-Vaxom®, Broncho-Munal®, Ommunal®, Paxoral®, Vaxoral®), in the treatment of established AD in children. Read More

    Simultaneous Occurrence of Varicella Zoster Virus-Induced Pancreatitis and Hepatitis in a Renal Transplant Recipient: A Case Report and Review of Literature.
    Perm J 2017 10;21. Epub 2017 Mar 10.
    Director of Gastroenterology, Hepatology and Interventional Endoscopy at the Fortis Hospital Mohali in Chandigarh, Mohali, Punjab, India.
    Introduction: Gastrointestinal complications are common after renal transplantation, including oral lesions, esophagitis, gastritis, diarrhea, and colon carcinoma. The differential diagnosis is difficult in this scenario because multiple factors such as drugs, infections, and preexisting gastrointestinal disease come into play.

    Case Presentation: We report a case of varicella zoster virus-induced pancreatitis and hepatitis in a renal transplant recipient. Read More

    The use of on-line SFE-SFC/MS/MS to analyze disease biomarkers in dried serum spots compared with serum analysis using LC/MS/MS.
    Rapid Commun Mass Spectrom 2017 Mar 23. Epub 2017 Mar 23.
    Division of Gastroenterology, Department of Internal Medicine, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, Hyogo, 650-0017, Japan.
    Rationale: The analytical stability and throughput of biomarker assays based on dried serum spots (DSS) are strongly dependent on the extraction process and determination method. In the present study, an on-line system based on supercritical fluid extraction-supercritical fluid chromatography coupled with tandem mass spectrometry (SFE-SFC/MS/MS) was established for analyzing the levels of disease biomarkers in DSS.

    Methods: The chromatographic conditions were investigated using the ODS-EP, diol, and SIL-100A columns. Read More

    Rapid corneal thinning and perforated ulcerative keratitis in a patient with relapsing polychondritis.
    Eye Vis (Lond) 2017 16;4. Epub 2017 Mar 16.
    0000 0004 1764 7206grid.415197.fThe Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China ; 0000 0004 1936 9000grid.21925.3dUPMC Eye Center, University of Pittsburgh, 203, Lothrop Street, 15231 Pittsburgh, PA USA.
    Background: To report rapid corneal thinning and perforation in a case with relapsing polychondritis.

    Case Presentation: A 43 year-old male diagnosed with relapsing polychondritis suffered from bilateral scleritis, bilateral swelling of pinna, saddle nose and tracheal stenosis. The patient presented with right eye pain and redness for one month. Read More

    Topical drug-induced subacute cutaneous lupus erythematosus isolated to the hands.
    Lupus Sci Med 2017 13;4(1):e000207. Epub 2017 Mar 13.
    The Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York, USA; Division of Rheumatology, Department of Medicine, New York University School of Medicine, New York, New York, USA.
    Subacute cutaneous lupus erythematosus (SCLE) is a well-defined subtype of lupus erythematosus, characterised by photosensitivity, annular and/or psoriasiform lesions, variable systemic involvement and presence of circulating SSA/anti-Ro antibodies. SCLE may be idiopathic or drug-induced. Both the idiopathic and drug-induced forms of SCLE are analogous in their clinical, serological and histological features. Read More

    Comparison of performance of the 2016 ACR-EULAR classification criteria for primary Sjögren's syndrome with other sets of criteria in Japanese patients.
    Ann Rheum Dis 2017 Mar 22. Epub 2017 Mar 22.
    Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
    Objectives: To compare the performance of the new 2016 American College of Rheumatology (ACR)-European League Against Rheumatism (EULAR) classification criteria for primary Sjögren's syndrome (SS) with 1999 revised Japanese Ministry of Health criteria for diagnosis of SS (JPN), 2002 American-European Consensus Group classification criteria for SS (AECG) and 2012 ACR classification criteria for SS (ACR) in Japanese patients.

    Methods: The study subjects were 499 patients with primary SS (pSS) or suspected pSS who were followed up in June 2012 at 10 hospitals in Japan. All patients had been assessed for all four criteria of JPN (pathology, oral, ocular, anti-SS-A/SS-B antibodies). Read More

    Value of routine upper gastrointestinal swallow study after laparoscopic sleeve gastrectomy.
    Surg Obes Relat Dis 2017 Feb 10. Epub 2017 Feb 10.
    Department of Radiology, Amiens University Hospital, Amiens, France.
    Background: Gastric leak (GL) is one of the main early-onset postoperative complications of sleeve gastrectomy (SG). Many institutions perform routine upper gastrointestinal (UGI) contrast studies within 24 hours of surgery, looking for GL or gastric stenosis and to determine the need for urgent re-exploration, but this examination delays oral feeding, can cause side effects and is responsible for systematic and probably unnecessary irradiation of the patient.

    Objective: Determine the efficacy of routine UGI contrast studies to predict postoperative complications after SG in a large population. Read More

    Oral cancer characteristics in France: Descriptive epidemiology for early detection.
    J Stomatol Oral Maxillofac Surg 2017 Feb 24. Epub 2017 Feb 24.
    General Tumour Registry of Calvados, Centre F.-Baclesse, 14000 Caen, France.
    Despite the frequency and lethality of oral cancers in France, there are no detailed general population data regarding the characteristics of these patients to fuel the public health authorities' reflections about early detection policies. Thus, the objective of this study was to determine, in the general population, the characteristics of both patients and tumours at the time of the diagnosis. A high-resolution, population-based study using 13 French registries was conducted on 1089 tumours diagnosed in 2010. Read More

    Necrotizing sialometaplasia of the parotid gland associated with facial nerve paralysis.
    J Stomatol Oral Maxillofac Surg 2017 Feb 3;118(1):63-65. Epub 2017 Feb 3.
    Service de stomatologie et chirurgie maxillofaciale, DHU FAST, groupe hospitalier Pitié-Salpêtrière Charles-Foix, AP-HP, 75013 Paris, France.
    Introduction: Necrotizing sialometaplasia is a benign inflammatory lesion involving most frequently the minor salivary gland of the hard palate. Involvement of the parotid gland is rare, involvement of the parotid gland associated with facial palsy is exceptional.

    Case Report: A 56-year-old male patient with Marfan syndrome presented with swelling and inflammation of the left parotid gland associated with progressively complete facial nerve paralysis. Read More

    [Information quality in general public French-speaking websites dedicated to oral cancer detection].
    J Stomatol Oral Maxillofac Surg 2017 Feb 3;118(1):20-28. Epub 2017 Feb 3.
    Faculté de médecine de Caen, université de Caen Basse-Normandie, 14032 Caen cedex 5, France; Service de chirurgie maxillo-faciale et plastique, centre hospitalier universitaire de Caen, 14000 Caen, France; Laboratoire EA 4652 microenvironnement cellulaire et pathologies, équipe BioconnecT, université de Caen Basse-Normandie, 14032 Caen cedex 5, France. Electronic address:
    Introduction: The goal set by the French highest national authorities in the 2014-2019 Cancer Plan is to "heal more sick persons by promoting early diagnosis through screening". Screening requires information. Nowadays, Internet allows for access to information "in one click". Read More

    [Actinomycosis Involving Chronic Pancreatitis: A Case Report with Literature Review].
    Korean J Gastroenterol 2017 Mar;69(3):191-195
    Department of Pathology, Kyungpook National University School of Medicine, Daegu, Korea.
    Actinomycosis is a slowly progressive, chronic infectious disease. It is caused by the genus Actinomyces, which are gram-positive anaerobic bacteria. It presents as a mass-like lesion, composed of bacterial nidus and characteristic granulomatous inflammatory fibrosis. Read More

    Incident acute pseudogout and prior bisphosphonate use: Matched case-control study in the UK-Clinical Practice Research Datalink.
    Medicine (Baltimore) 2017 Mar;96(12):e6177
    Research Institute for Primary Care and Health Sciences, Keele University, Keele, Staffordshire, UK.
    Oral bisphosphonates are the most commonly used drugs to treat postmenopausal osteoporosis. Acute pseudogout is anecdotally reported to occur following bisphosphonate initiation but empirical data are lacking. We investigated whether treatment with oral bisphosphonates is a risk factor for incident acute pseudogout. Read More

    Effect of Biperiden Treatment in Acute Orofacial and Extremity Dyskinesia With Methylphenidate Therapy.
    Pediatr Emerg Care 2017 Mar 21. Epub 2017 Mar 21.
    From the Departments of *Pediatric Neurology and †Neurosurgery, Karadeniz Technical University School of Medicine, Trabzon; and ‡Emergency Clinic, Kent Hospital; and §Clinic of Psychology, Giresun Prof Dr Ilhan Ozdemir Hospital, Giresun, Turkey.
    Methylphenidate is a stimulant drug commonly prescribed to individuals with attention-deficit/hyperactivity disorder. The suggested underlying mechanism of acute dyskinesias is dopaminergic transmission increase. We describe a 9-year-old boy with a diagnosis of attention-deficit/hyperactivity disorder admitted to emergency clinic with primarily orofacial and extremity dyskinesia after administration of a first dose of 18 mg OROS (osmotic [controlled] release oral) methylphenidate (Concerta). Read More

    Evaluation of Dentoalveolar Trauma in Children and Adolescents: a Modified Classification System and Surgical Treatment Strategies for Its Management.
    J Craniofac Surg 2017 Mar 21. Epub 2017 Mar 21.
    University Department of Oral and Maxillofacial Surgery at 'A. & P. Kyriakou' Children's Hospital of Athens, Dental School, University of Athens, Athens, Greece.
    Objective: To retrospectively analyze dentoalveolar trauma in pediatric patients, propose a modified classification, and delineate an approach for its urgent care from the surgeon's perspective.

    Patients And Methods: Clinical records of patients, attended at the 'A. and P. Read More

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