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    Elimination diet and the development of multiple tree-nut allergies.
    Pediatr Res 2017 May 26. Epub 2017 May 26.
    Division of Allergy, Immunology and Rheumatology.
    BACKGROUNDDespite its high prevalence, relatively little is known about the characteristics of patients with multiple tree-nuts allergies.METHODSPatients (n=60, aged 4-15 years), recruited for a multiple food (tree-nuts, peanut, milk, egg, soy, sesame and wheat) oral immunotherapy (OIT) study, filled a questionnaire on their initial allergy evaluation. Medical records were reviewed. Read More

    Simultaneous Detection of Oral Pathogens in Subgingival Plaque and Prostatic Fluid of Men with Periodontal and Prostatic Diseases.
    J Periodontol 2017 May 26:1-11. Epub 2017 May 26.
    Department of Urology, Case Western Reserve University and University Hospitals Cleveland Medical Center, Cleveland, Ohio 44106 USA.
    Background: Chronic prostatitis (CP) and benign prostatic hyperplasia (BPH) are complex inflammatory conditions for which the etiological determinants are still poorly defined. Periodontitis is caused by subgingival colonizing bacteria in the oral cavity. The causal effect of periodontal disease on prostatic inflammation has not been established. Read More

    Dental and periodontal health, and microbiological and salivary conditions in patients with or without diabetes undergoing haemodialysis.
    Int Dent J 2017 Jun 2;67(3):186-193. Epub 2017 Feb 2.
    Department of Cariology, Endodontology, and Periodontology, University of Leipzig, Leipzig, Germany.
    Objective: The aim of this cross-sectional study was to evaluate the dental and periodontal health, as well as the microbiological and salivary conditions, of patients with and without diabetes mellitus (DM) who are receiving haemodialysis.

    Methods: One-hundred and fifty-nine haemodialysis patients were included and divided into groups according to the pre-existing diabetes status: DM or no DM. The oral examination included dental findings and assessment of the periodontal situation. Read More

    Language Development and Impairment in Children with Mild to Moderate Sensorineural Hearing Loss.
    J Speech Lang Hear Res 2017 May 24:1-17. Epub 2017 May 24.
    Division of Psychology and Language Sciences, University College London (UCL), United Kingdom.
    Purpose: The goal of this study was to examine language development and factors related to language impairments in children with mild to moderate sensorineural hearing loss (MMHL).

    Method: Ninety children, aged 8-16 years (46 children with MMHL; 44 aged-matched controls), were administered a battery of standardized language assessments, including measures of phonological processing, receptive and expressive vocabulary and grammar, word and nonword reading, and parental report of communication skills. Group differences were examined after controlling for nonverbal ability. Read More

    Acute paraparesis and sensory loss following intravenous corticosteroid administration in a case of longitudinally extensive transverse myelitis caused by spinal dural arteriovenous fistula: case report and review of literature.
    Spinal Cord Ser Cases 2017 18;3:17025. Epub 2017 May 18.
    Department of Neurology, Cleveland Clinic, Cleveland, Ohio, USA.
    Introduction: The underlying causes of longitudinally extensive transverse myelitis (LETM) are broad and include inflammatory processes, compression and spinal dural arteriovenous fistula (SDAVF). Presenting symptoms of SDAVF are nonspecific and often go misdiagnosed. Acute clinical deterioration from SDAVF has been described following exertion or valsalva. Read More

    Tale of the Tails, the Missing Postpartum IUCD Strings.
    J Obstet Gynaecol India 2017 Jun 23;67(3):202-207. Epub 2016 Sep 23.
    District Headquarters Hospital, Balangir, 767001 Odisha India.
    Introduction: Using an intrauterine device (IUD) is many times safer than pregnancy and more effective in preventing pregnancy than oral contraceptives, condoms, spermicidal, any barrier method, or natural family planning. Benefits of healthy timing and spacing of pregnancy are many. Postpartum contraception is becoming popular after introduction of PPIUCD services. Read More

    Patient safety: reducing the risk of wrong tooth extraction.
    Br Dent J 2017 May;222(10):759-763
    Clinical Head of Division, University Dental Hospital of Manchester, Manchester, M15 6FH.
    Over recent years there has been an increased emphasis on improving patient safety in all branches of medicine, with reducing wrong tooth extraction being a priority in dentistry. The true incidence of wrong tooth extraction is unknown but it is considered an avoidable harm and is a significant source of dental litigation. Interventions to reduce wrong tooth extraction include educational programmes encompassing human factor training, patient assisted identification, the use of checklists, marking of surgical sites and implementation of patient safety guidelines. Read More

    The healthcare system and the provision of oral healthcare in European Union member states. Part 8: Italy.
    Br Dent J 2017 May;222(10):809-817
    National Institute for Health and Welfare, Helsinki, Finland, Professor of Dental Public Health, Institute of Clinical Dentistry, Arctic University of Norway, PO Box 30.00271.
    In Italy healthcare is provided for all Italian citizens and residents and it is delivered mainly by public providers, with some private or private-public entities. Italy's public healthcare system - the Servizio Sanitario Nazionale (SSN) - is organised by the Ministry of Health and administered on a devolved regional basis. It is financed by general taxation that provides universal coverage, largely free of charge at the point of service. Read More

    Intraocular minocycline for the treatment of ocular pythiosis.
    Am J Health Syst Pharm 2017 Jun;74(11):821-825
    Ophthalmology Department, La Paz University Hospital, Madrid, Spain.
    Purpose: A case of ocular pythiosis successfully treated with surgery and intraocular and oral minocycline is reported.

    Summary: A 30-year-old man who wore corrective contact lenses traveled to Brazil and Colombia where he swam in salt and fresh waters while wearing contact lenses. He sought treatment at an emergency department after 2 weeks of suffering with a painful corneal ulcer, redness, and loss of vision in his right eye that had been treated at other centers with ophthalmic moxifloxacin for 10 days and with fortified topical antibiotics (amikacin and vancomycin) for 2 days. Read More

    Neurological manifestations of Behçet's disease: Case report and literature review.
    Reumatol Clin 2017 May 22. Epub 2017 May 22.
    Servicio de Neurología, Hospital Clínico Universitario Lozano Blesa, Zaragoza, España.
    Neurological involvement in Behçet's disease is rare, especially at the onset. It can present in the form of parenchymal changes or as damage to the vascular structures in its nonparenchymal form. The coexistence of both kinds of manifestations in the same patient is exceptional. Read More

    An update of 77 cases diagnosed as oral hemangiomas based on GLUT-1 positivity.
    Exp Mol Pathol 2017 May 22. Epub 2017 May 22.
    Postgraduate Program, Oral Pathology, Federal University of Rio Grande do Norte, Natal, RN, Brazil.
    Objectives: To evaluate cases diagnosed as "oral hemangiomas" based on the immunohistochemical expression of human glucose transporter protein (GLUT-1) and on histopathological features, and to investigate whether the classification proposed by the ISSVA was used correctly to classify these lesions.

    Material And Methods: All cases stored in the archives of an Oral Pathology Service and diagnosed as "oral hemangiomas" were reviewed. Seventy-seven cases were analyzed regarding the expression of GLUT-1. Read More

    Alcelaphine gammaherpesvirus 1-induced malignant catarrhal fever in a Watusi ( Bos taurus africanus) steer in a North American game park.
    J Vet Diagn Invest 2017 May 1:1040638717708392. Epub 2017 May 1.
    Department of Biomedical Sciences, Oregon State University, Corvallis, OR (Bildfell).
    A 10-y-old Watusi ( Bos taurus africanus) steer housed at a drive-through game park in Winston, Oregon developed severe clinical illness including fever, marked nasal discharge, injected scleral and conjunctival membranes, plus oral hemorrhages and erosions. The animal responded poorly to supportive treatment and was euthanized. Additional gross findings at postmortem examination included papules and erosive lesions on the tongue, hemorrhagic large intestine, and multifocal cardiac hemorrhages. Read More

    Proteomics investigation of OSCC-specific salivary biomarkers in a Hungarian population highlights the importance of identification of population-tailored biomarkers.
    PLoS One 2017 18;12(5):e0177282. Epub 2017 May 18.
    Department of Periodontology, Faculty of Dentistry, University of Debrecen, 1. Egyetem ter, Debrecen, Hungary.
    Oral squamous cell carcinoma (OSCC) accounting for about 90% of malignant oral lesions is the 6th most common malignancy worldwide. Diagnostic delay may contribute to dismal survival rate therefore, there is a need for developing specific and sensitive biomarkers to improve early detection. Hungarian population occupies the top places of statistics regarding OSCC incidence and mortality figures therefore, we aimed at finding potential salivary protein biomarkers suitable for the Hungarian population. Read More

    Quantitative prediction of oral cancer risk in patients with oral leukoplakia.
    Oncotarget 2017 May 2. Epub 2017 May 2.
    Department of Oral Medicine, Beijing Stomatological Hospital, Capital Medical University, Beijing, China.
    Exfoliative cytology has been widely used for early diagnosis of oral squamous cell carcinoma. We have developed an oral cancer risk index using DNA index value to quantitatively assess cancer risk in patients with oral leukoplakia, but with limited success. In order to improve the performance of the risk index, we collected exfoliative cytology, histopathology, and clinical follow-up data from two independent cohorts of normal, leukoplakia and cancer subjects (training set and validation set). Read More

    Intradiscal application of a PCLA-PEG-PCLA hydrogel loaded with celecoxib for the treatment of back pain in canines: what's in it for humans?
    J Tissue Eng Regen Med 2017 May 19. Epub 2017 May 19.
    Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, The Netherlands.
    Chronic low back pain is a common clinical problem in both the human and canine population. Current pharmaceutical treatment often consists of oral anti-inflammatory drugs to alleviate pain. Novel treatments for degenerative disc diseases focus on local application of sustained released drug formulations. Read More

    Effects of quadriceps functional exercise with isometric contraction in the treatment of knee osteoarthritis.
    Int J Rheum Dis 2017 May 25. Epub 2017 May 25.
    Department of Ophthalmology, the Second Hospital of Jilin University, Changchun, Jilin, China.
    Objective: This study aims to investigate the effects of a quadriceps isometric contraction exercise method in the treatment of knee osteoarthritis (OA).

    Methods: A total of 250 patients with a confirmed diagnosis of knee OA were enrolled. The patients were randomly divided into an exercise treatment test group (128 patients) and a traditional treatment control group (122 patients). Read More

    Thromboembolic and bleeding complications during oral anticoagulation therapy in cancer patients with atrial fibrillation: a Danish nationwide population-based cohort study.
    Cancer Med 2017 May 19. Epub 2017 May 19.
    Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
    Coexisting cancer in patients with atrial fibrillation (AF) has been associated with thromboembolism and bleeding. We used Danish population-based medical databases to conduct a population-based cohort study that included all AF patients who redeemed a prescription for vitamin K antagonists (VKA) or non-VKA oral anticoagulant (NOAC) between July 2004 and December 2013. We characterized these patients according to the presence (N = 11,855) or absence (N = 56,264) of a cancer diagnosis before redemption of their oral anticoagulant prescription, and then examined their 1-year risk of thromboembolic or bleeding complications or death. Read More

    NUT carcinoma presenting in the palate - a case report.
    APMIS 2017 May 25. Epub 2017 May 25.
    Department of Oral & Maxillofacial Surgery, Rigshospitalet, Copenhagen, Denmark.
    NUT carcinomas (NC) are rare and aggressive tumours characterized by chromosomal rearrangements of the gene encoding for nuclear protein of the testis (NUT) located on chromosome 15q14. This article presents a case of a 60-year-old woman diagnosed with NC presenting as a fast growing primary tumour in the right palate. Further evaluation revealed a tumour mass in the lungs and widespread metastases. Read More

    A New Predictive Model for Acute Gastrointestinal Bleeding in Patients Taking Oral Anticoagulants: A Cohort Study.
    J Gastroenterol Hepatol 2017 May 19. Epub 2017 May 19.
    Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, Kohnodai Hospital, Chiba, Japan.
    Background: We developed a predictive model of long-term gastrointestinal (GI) bleeding risk in patients receiving oral anticoagulants and compared it with the HAS-BLED score.

    Methods: We periodically followed a cohort of 508 patients taking oral anticoagulants (66 direct oral anticoagulants users and 442 warfarin users). Absence of GI bleeding at an initial examination, and any subsequent GI bleeding, were confirmed endoscopically. Read More

    Obesity is Inversely Related to the Risks of Dental Caries in Korean Adults.
    Oral Dis 2017 May 20. Epub 2017 May 20.
    Department of Periodontics, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
    Objective: This study investigated whether obesity is linked with dental caries. The present study hypothesized that obesity may influence the number or prevalence of dental caries in Korean adults.

    Subjects And Methods: Data was derived from Korea National Health and Nutrition Examination Survey performed at 2008-2010. Read More

    A case of primordial odontogenic tumor: A new entity in the latest WHO classification (2017).
    Pathol Int 2017 May 25. Epub 2017 May 25.
    Department of Oral and Maxillofacial Pathobiology, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
    Primordial odontogenic tumor (POT) is a rare lesion in the jaw which has been included as a new entity of benign mixed epithelial and mesenchymal odontogenic tumour in the latest World Health Organization (WHO) classification (2017). Only seven cases have been reported. It typically occurs in the posterior mandible. Read More

    Idiopathic Lymphoplasmacellular Mucositis of the Lips: A Case Report and Review of the Literature.
    J Cutan Pathol 2017 May 23. Epub 2017 May 23.
    Department of Dermatology, Chang Gung Memorial Hospital, Taipei, Linko and Keelung, Taiwan.
    Idiopathic lymphoplasmacellular mucositis (ILPM) is a group of disorders histologically characterized by dense infiltrates of lymphocytes and plasma cells in submucosa. These lesions are initially observed on the glans penis and vulva, and later on buccal mucosa, lips, gingiva, tongue, epiglottis, larynx, and other mucosal surfaces have also been reported. We have reviewed the previously reported cases of ILPM with lip involvement, outlining the clinical presentation, treatment and outcome of the entity to date. Read More

    Correlation between salivary and serum anti-desmoglein 1 and 3 antibody titres using ELISA and between anti-desmoglein levels and disease severity in pemphigus vulgaris.
    Clin Exp Dermatol 2017 May 22. Epub 2017 May 22.
    Department of Immunopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
    ELISA for anti-desmoglein antibodies (Dsg) is commonly used for diagnosis and assessment of treatment response in pemphigus vulgaris (PV). The present study was conducted to assess the relationship between salivary and serum Dsg1 and Dsg3 levels, and whether salivary Dsg1 and Dsg3 levels correlate with clinical disease severity of oral mucosal lesions in PV. In total 43, patients with PV with predominantly mucosal involvement were recruited. Read More

    Can resonance frequency analysis (RFA) detect narrow marginal bone defects around dental implants? An ex-vivo animal pilot study.
    Aust Dent J 2017 May 25. Epub 2017 May 25.
    Clinical Associate Professor, director in Implant Dentistry, Oral Rehabilitation, Faculty of Dentistry, University of Hong Kong.
    Background: Resonance Frequency Analysis (RFA) is widely applied to assess implant stability, as expressed by Implant Stability Quotient (ISQ). However, the relation between ISQ value and the presence and extent of narrow marginal bone defects around implants has not been documented.

    Purpose: To investigate the potential of RFA devices to identify the presence and extent of marginal bone defects around implants, as expressed by the ISQ values. Read More

    Knowledge, diagnosis and management of dentine hypersensitivity: a national survey of dentists in Nigeria.
    Int Dent J 2017 May 20. Epub 2017 May 20.
    Department of Preventive Dentistry, Faculty of Dental Sciences, College of Medicine, University of Lagos, Lagos, Nigeria.
    Aim: To assess the knowledge of Nigerian dentists regarding dentine hypersensitivity (DH) and their methods of diagnosis and management.

    Methods: A cross-sectional questionnaire-based study of dentists practicing in all six geopolitical zones of Nigeria was conducted. The questionnaire focussed on participant's demography, exposure to patients with DH, knowledge-based questions, diagnosis and management of DH. Read More

    Meta-analysis of magnetic resonance imaging accuracy for diagnosis of oral cancer.
    PLoS One 2017 24;12(5):e0177462. Epub 2017 May 24.
    Graduate Program in Public Health (PPGSCol), Unidade Acadêmica de Ciências da Saúde (UNASAU), Universidade do Extremo Sul Catarinense (UNESC), Criciúma, SC, Brazil.
    Objective: To establish the diagnostic accuracy of magnetic resonance imaging (MRI) as an auxiliary means for the diagnosis of oral cancer through a systematic review and meta-analysis.

    Methods: An exhaustive search of publications from 1986 to 2016 was performed of Medline, Embase and Cochrane (and related databases), including grey literature. Primary diagnostic accuracy studies that assessed oral cancer (target condition) using MRI (index test) were included. Read More

    Clinical impact of chronic obstructive pulmonary disease on non-cystic fibrosis bronchiectasis. A study on 1,790 patients from the Spanish Bronchiectasis Historical Registry.
    PLoS One 2017 18;12(5):e0177931. Epub 2017 May 18.
    Department of Pneumology, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
    Background: Few studies have evaluated the coexistence of bronchiectasis (BE) and chronic obstructive pulmonary disease (COPD) in series of patients diagnosed primarily with BE. The aim of this study was to analyse the characteristics of patients with BE associated with COPD included in the Spanish Bronchiectasis Historical Registry and compare them to the remaining patients with non-cystic fibrosis BE.

    Methods: We conducted a multicentre observational study of historical cohorts, analysing the characteristics of 1,790 patients who had been included in the registry between 2002 and 2011. Read More

    Failure of Osseointegrated Dental Implant After Alveolar Nerve Transposition: A Report of an Unusual Complication and Surgical Management.
    Implant Dent 2017 May 24. Epub 2017 May 24.
    *Surgeon, Oral and Maxillofacial Surgery Department, University Hospital, Federal University of Piaui, Picos, Brazil. †Professor, Department of Clinical and Social Dentistry, Federal University of Paraiba, Joao Pessoa, Paraiba, Brazil. ‡Professor, Department of Oral and Maxillofacial Surgery and Periodontology, School of Dentistry of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Sao Paulo, Brazil. §Professor, Department of Oral Diagnosis, Division of Oral and Maxillofacial Surgery Piracicaba Dental School, Piracicaba, Sao Paulo, Brazil.
    Purpose: To describe an unusual case of mandibular fracture after osseointegrated dental implant removal placed after inferior alveolar nerve transposition.

    Report Of Case: The patient underwent inferior nerve transposition for implant placement due to lack of interarch space. Two months after metal-ceramic crowns installation, the patient began to complain of pain in the region of the implant. Read More

    Chronic paracoccidioidmycosis in a woman with Crohn Disease.
    Dermatol Online J 2017 Apr 15;23(4). Epub 2017 Apr 15.
    Department of Diagnosis and Surgery, Araraquara Dental School, UNESP - Univ Estadual Paulista, Araraquara, São Paulo, Brazil.
    We report a rare case of chronic paracoccidioidomycosis(PCM) in a woman with Crohn disease in the setting of treatment with azathioprine and mesalazine. Serum tests for antigens to Paracoccidioides brasiliensis, Histoplasma capsulatum, and Aspergillus fumigatus were negative. An incisional biopsy of an oral lesion with periodic acid-schiff and Grocott-methenamine silver stains revealed chronic granulomatous inflammation with multinucleated giant cells with Paracoccidioides brasiliensis within the cytoplasm, confirming the diagnosis of PCM. Read More

    Tuberous sclerosis complex (Bourneville-Pringle disease) in a 25-year- old female with bilateral renal angiomyolipoma and secondary hypertension.
    Saudi J Kidney Dis Transpl 2017 May-Jun;28(3):633-638
    Department of Internal Medicine, Hedi Chaker Hospital, Sfax, Tunisia.
    Tuberous sclerosis or tuberous sclerosis complex (TSC) is an autosomal dominant inherited neurocutaneous disorder that variably affects the brain, skin, kidneys, heart, and other organs. It is characterized by skin and renal lesions in addition to central and peripheral nervous system tumors, with neurological and psychiatric findings. We report such a rare case of tuberous sclerosis in a 25-year-old female who presented with abdominal pain and hypertension. Read More

    Clinico-mycological study of dermatophytic infections and their sensitivity to antifungal drugs in a tertiary care center.
    Indian J Dermatol Venereol Leprol 2017 May 22. Epub 2017 May 22.
    Department of Dermatology and Venereology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
    Background: Worldwide, dermatophytic infections are running a chronic course either due to ineffective treatment or emerging drug resistance. In the past three decades, there has been an increase in incidence and non-responsiveness to conventional antifungals, which suggests that there is a need of antifungal sensitivity testing.

    Aims: This study was aimed at identifying clinico-mycological pattern of dermatophytic infections in patients attending thedermatology outpatient department of a tertiary care hospital, and to obtain the sensitivity pattern of isolates against six commonly used oral antifungals (fluconazole, terbinafine, itraconazole, ketoconazole, griseofulvin and voriconazole). Read More

    Influence of Temperature on Cerebellar Metabolite Levels.
    Int J Hyperthermia 2017 May 23:1-10. Epub 2017 May 23.
    b Department of Radiology , Yantai Affiliated Hospital of Binzhou Medical University , Yantai, 264100 , Shandong , China.
    Objective: The cerebellum is extremely sensitive to heat-induced injury because of the abundance of Purkinje cells. This study explored the influence of temperature on cerebellar metabolite levels by magnetic resonance spectroscopy (MRS).

    Materials And Methods: Ten healthy volunteers were recruited to undergo a MRS examination in the summer and winter. Read More

    [Interstitial cystitis : Diagnosis and pharmacological and surgical therapy].
    Urologe A 2017 May 24. Epub 2017 May 24.
    Klinik für Urologie, Universitätsklinik Leipzig AöR, Liebigstraße 20, 04103, Leipzig, Deutschland.
    Interstitial cystitis/bladder pain syndrome (IC/BPS) is a chronic debilitating condition which generally has a severely negative impact on quality of life. An autoimmune genetic predisposition correlates with the theory of pathogenesis. Diagnosis requires history, diaries, physical examination, exclusion of other diseases, cystoscopy with or without hydrodistension and/or bladder biopsy. Read More

    Interdisciplinary Management of Head and Neck Vascular Anomalies: Clinical Presentation, Diagnostic Findings and Minimalinvasive Therapies.
    Eur J Radiol Open 2017 14;4:63-68. Epub 2017 May 14.
    Department of Otorhinolaryngology and Head and Neck Surgery, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.
    Objectives: Vascular anomalies are included in the 30 000 rare diseases worldwide affecting less than 5/10 000 people. Depending on their morphology and biological properties, they can cause varied disorders with organ involvement. Almost 60% of vascular anomalies have a predilection for the head and neck region in children. Read More

    Neonatal Diabetes: Case Report of a 9-Week-Old Presenting Diabetic Ketoacidosis Due to an Activating ABCC8 Gene Mutation.
    J Investig Med High Impact Case Rep 2017 Jan-Mar;5(1):2324709617698718. Epub 2017 Mar 24.
    The Children's Hospital at Saint Francis, Tulsa, OK, USA.
    Context: Neonatal diabetes mellitus, a rare condition occurring in approximately 1 in 500 000 live births, is defined as insulin-requiring hyperglycemia presenting in the first months of life. Neonatal diabetes can be transient or permanent, with studies characterizing the condition as a monogenic disorder. Case Report: We describe a case of a 9-week-old infant with neonatal diabetes who presented in diabetic ketoacidosis due to a mutation affecting the ABCC8 gene that encodes the SUR1 subunit of the potassium ATP channel. Read More

    Treatment Challenges of Prosthetic Hip Infection with Associated Iliacus Muscle Abscess: Report of 5 Cases and Literature Review.
    J Bone Jt Infect 2017 20;2(3):127-135. Epub 2017 Mar 20.
    Cleveland Clinic Foundation, 9500 Euclid Ave.Cleveland, OH 44195, USA.
    Prosthetic joint infection is an unfortunate though well-recognized complication of total joint arthroplasty. An iliacus and/or iliopsoas muscle abscess is a rarely documented presentation of hip prosthetic joint infection. It is thought an unrecognized retroperitoneal nidus of infection can be a source of continual seeding of the prosthetic hip joint, prolonging attempts to eradicate infection despite aggressive debridement and explant attempts. Read More

    Diabetic nephropathy: Time to withhold development and progression - A review.
    J Adv Res 2017 Jul 21;8(4):363-373. Epub 2017 Apr 21.
    Rheumatology and Rehabilitation Department, School of Medicine, Cairo University, Egypt.
    The recent discoveries in the fields of pathogenesis and management of diabetic nephropathy have revolutionized the knowledge about this disease. Little was added to the management of diabetic nephropathy after the introduction of renin angiotensin system blockers. The ineffective role of the renin- angiotensin system blockers in primary prevention of diabetic nephropathy in type 1 diabetes mellitus necessitated the search for other early therapeutic interventions that target alternative pathogenic mechanisms. Read More

    Frequency and locations of systemic metastases in Merkel cell carcinoma by imaging.
    Acta Radiol Open 2017 Mar 24;6(3):2058460117700449. Epub 2017 Mar 24.
    Medical Imaging Center, Helsinki University Hospital, Helsinki, Finland.
    Background: The primary neuroendocrine skin cancer, Merkel cell carcinoma (MCC), has a well-known predilection to metastasize systemically. However, the experience of systemic metastases in MCC is mainly disseminated through case reports due to the rarity of MCC.

    Purpose: To elucidate the frequency and locations of systemic metastasis in MCC by reviewing the imaging of patients with metastatic MCC in a national cohort. Read More

    Comparative evaluation of diode laser ablation and surgical stripping technique for gingival depigmentation: A clinical and immunohistochemical study.
    Int J Health Sci (Qassim) 2017 Apr-Jun;11(2):51-58
    Department of Periodontics and Oral Implantology, Pacific Dental College & Hospital, Udaipur, Rajasthan, India.
    Introduction: There are various treatment modalities to remove the black patches of melanin pigmentation. The aim of the study is to clinically compare the diode laser ablation and surgical stripping technique for gingival depigmentation and to evaluate their effect on the histological changes in melanocyte activity.

    Materials And Methods: A total of 40 sites of 20 patients with bilateral melanin hyperpigmentation were treated with the surgical stripping and diode laser ablation technique. Read More

    Comparative evaluation of different histoprocessing methods.
    Int J Health Sci (Qassim) 2017 Apr-Jun;11(2):28-34
    Department of Oral Pathology & Microbiology, Genesis Institute of Dental Sciences & Research, Ferozepur, Punjab, India.
    Objectives: Tissue processing for years is carried out by the conventional method, which is a time-consuming technique resulting in 1-day delay in diagnosis. However, in this area of modernization and managed care, rapid diagnosis is increasingly desirable to fulfill the needs of clinicians. The objective of the present study was to compare and determine the positive impact on turnaround times of different tissue processing methods by comparing the color intensity, cytoplasmic details, and nuclear details of the tissues processed by three methods. Read More

    The challenge of the approach to oral cancer in primary health care.
    Cien Saude Colet 2017 May;22(5):1579-1587
    Universidade de Fortaleza. Fortaleza CE Brasil.
    The aim of this study was to understand the performance of dentists in public health about mouth cancer. A cross-sectional study was performed whit 121 dentists from Fortaleza Health Department, interviewed through a semi-structured questionnaire. The study did not identify statistically significant difference regarding the ability to perform biopsy by gender, year of graduation, expertise or time of public service. Read More

    Ductal eccrine carcinoma of the axilla: a diagnostic pitfall.
    An Bras Dermatol 2017 Mar-Apr;92(2):239-242
    Department of Dermatology, Instituto Português de Oncologia de Lisboa - Lisboa, Portugal.
    Ductal eccrine carcinoma (DEC) is a rare sweat gland carcinoma with ductular differentiation. Clinically, it is characterized by a slowly growing, hardened plaque or nodule predominantly located on the head and neck. Histologically, DEC shares similar features to invasive breast carcinoma, thus causing great diagnostic challenges. Read More

    Nasalance scores of Brazilian Portuguese speakers at 5 years of age.
    Codas 2017 May 22;29(3):e20160197. Epub 2017 May 22.
    Hospital de Reabilitação de Anomalias Craniofaciais, Universidade de São Paulo - USP - Bauru (SP), Brasil.
    Purpose: To determine nasalance scores of Brazilian Portuguese speaking children without evident speech disorders, language delay and orofacial deformities, at age 5 years, and analyze differences between types of speech samples and genders.

    Methods: Twenty children were analyzed, 11 males, age ranging from 4 years and 10 months to 5 years and 11 months. The Nasometer II 6450 (KayPENTAX) was used for nasalance assessment. Read More

    Palisaded neutrophilic and granulomatous dermatitis as a novel cause of hypercalcemia: A case report.
    Medicine (Baltimore) 2017 May;96(21):e6968
    aThird Department of Internal Medicine, Hokkaido P.W.F.A.C., Obihiro-Kosei General Hospital, Obihiro bDepartment of Developmental Biology of Hard Tissue, Graduate School of Dental Medicine, Hokkaido University, Sapporo cDepartment of Diabetes and Endocrinology, Sapporo Medical Center, NTT EC, Sapporo dDivision of Dermatology eDivision of Pathology, Hokkaido P.W.F.A.C., Obihiro-Kosei General Hospital, Obihiro, Japan.
    Rationale: Palisaded neutrophilic and granulomatous dermatitis (PNGD) is a benign, inflammatory dermatosis with distinct histopathological features often observed in patients with systemic diseases. There were no reports of PNGD without underlying systemic diseases as an underlying cause of hypercalcemia. Herein, we report a case of a 62-year-old man with hypercalcemia due to PNGD, but with no underlying systemic diseases, including tuberculosis, sarcoidosis, or vasculitis. Read More

    An overview of challenges to eradication of Helicobacter pylori infection and future prospects.
    Eur Rev Med Pharmacol Sci 2017 May;21(9):2199-2219
    Department of Bioengineering, Chemical-Metallurgical Faculty, Yildiz Technical University, Istanbul, Turkey.
    The eradication of H. pylori infection continues to be a challenge due to the evolution of drug-resistant bacteria, lack of a gold standard diagnostic method, and ineffectiveness of current vaccines. Additionally, there still is no consensus in the literature about the main source of gastric H. Read More

    Physician-Directed Diabetes Education without a Medication Change and Associated Patient Outcomes.
    Diabetes Metab J 2017 May 12. Epub 2017 May 12.
    Division of Endocrinology and Metabolism, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
    Background: When patients with diabetes mellitus (DM) are first referred to a hospital from primary health care clinics, physicians have to decide whether to administer an oral hypoglycemic agent (OHA) immediately or postpone a medication change in favor of diabetes education regarding diet or exercise. The aim of this study was to determine the effect of diabetes education alone (without alterations in diabetes medication) on blood glucose levels.

    Methods: The study was conducted between January 2009 and December 2013 and included patients with DM. Read More

    Evaluation of metal artefact reduction in cone-beam computed tomography images of different dental materials.
    Clin Oral Investig 2017 May 23. Epub 2017 May 23.
    Piracicaba Dental School, Department of Oral Diagnosis, Area of Oral Radiology, Piracicaba Dental School, University of Campinas, 901, Limeira Avenue, Piracicaba, Sao Paulo, 13414-903, Brazil.
    Objective: The aim of this study is to evaluate the efficacy of metal artefact reduction (MAR) in different dental materials with Picasso Trio cone-beam computed tomography (CBCT) scanner.

    Materials And Methods: Three imaging phantoms were custom-made of acrylic resin. Each phantom presented three cylinders of the same material: dental amalgam alloy, gutta-percha or aluminium-copper alloy. Read More

    Mandible metastasis of small cell lung cancer mimicking a residual cyst.
    Autops Case Rep 2017 Jan-Mar;7(1):37-41. Epub 2017 Mar 30.
    Stomatology Department - A.C. Camargo Cancer Center, São Paulo/SP - Brazil.
    Small cell lung carcinoma (SCLC) is an uncommon tumor characterized by an aggressive behavior with early metastasis, usually to the contralateral lung, liver, brain, and bones. There are only five cases of this particular tumor metastasizing to the oral cavity described in the English literature. We present the case of metastatic SCLC in the mandible with radiographic findings resembling a residual cyst. Read More

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