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    1 OF 2820

    Recurrence rate of odontogenic keratocyst treated by enucleation and peripheral ostectomy: Retrospective case series with up to 12 years of follow-up.
    Med Oral Patol Oral Cir Bucal 2018 Jun 20. Epub 2018 Jun 20.
    Hacettepe University Faculty of Dentistry Department of Oral and Maxillofacial Surgery Ankara, Turkey
    Background: Odontogenic keratocysts have been reported with high recurrence rates in the literature so various treatment modalities from simple enucleation to resection have been performed to achieve the cure. The purpose of this retrospective study was to investigate the recurrence rate of odontogenic keratocysts (OKCs) treated by enucleation and peripheral ostectomy.

    Material And Methods: An electronic search of the database of the Hacettepe University, Faculty of Medicine, Department of Pathology, was undertaken to identify patients histologically diagnosed with OKCs treated at Department of Oral and Maxillofacial Surgery between 2001 and 2015. Read More

    Oral verruciform xanthoma: Report of 13 new cases and review of the literature.
    Med Oral Patol Oral Cir Bucal 2018 Jun 20. Epub 2018 Jun 20.
    Department of Oral Medicine and Oral Pathology School of Dentistry National and Kapodistrian University of Athens Greece, 2 Thivon Str, 11527, Goudi, Athens, Greece
    Background: Oral verruciform xanthoma (OVX) is a rare lesion. The purpose of the present study is to describe the clinical features of 13 OVXs and review all cases reported in the English literature.

    Material And Methods: Thirteen cases of OVX diagnosed during a 47-year period were retrospectively collected. Read More

    Clinicopathological study of oral focal mucinosis: a retrospective case series.
    Med Oral Patol Oral Cir Bucal 2018 Jun 20. Epub 2018 Jun 20.
    Departamento de Odontologia Universidade Federal do Rio Grande do Norte Av. Senador Salgado Filho, 1787, Lagoa Nova CEP 59056-000 Natal, RN, Brasil
    Background: Oral focal mucinosis (OFM) is a rare soft tissue lesion of unknown etiology that exhibits tumor-like growth. It is considered the oral counterpart of cutaneous focal mucinosis or cutaneous myxoid cyst. This is a retrospective study of oral OFM diagnosed over a period of 42 years at an oral pathology service. Read More

    Can different stages of leprosy treatment influence the profile of oral health? Oral status in leprosy.
    Med Oral Patol Oral Cir Bucal 2018 Jun 20. Epub 2018 Jun 20.
    University of Cuiabá-UNIC-Mato Grosso
    Background: The aim of study was to evaluate the oral health status, salivary flow and halitosis among individuals diagnosed with leprosy as compared with healthy subjects.

    Material And Methods: A sample of 160 individuals was allocated into four groups, as follows: (G1) individuals with complete leprosy treatment; (G2) individuals diagnosed with leprosy and under multi-drug therapy; (G3) individuals diagnosed with leprosy not yet under treatment; and (G4) healthy individuals. Then individuals were submitted to periodontal clinical examination (visible plaque index, bleeding index, depth of probing and clinical attachment level); DMFT index (decayed-missing-filled teeth index); evaluation of salivary flow and halitosis using a halimeter equipment (Interscan Corp, Chatsworth, CA, USA). Read More

    Recurrent aphthous ulceration: an epidemiological study of etiological factors, treatment and differential diagnosis.
    An Bras Dermatol 2018 Jun;93(3):341-346
    Oral Pathology Post-Graduation Program, Universidade Federal do Rio Grande do Norte, Natal, RN, Brazil.
    Background: Recurrent aphthous ulcerations are common benign ulcerated lesions on the mouth, whose etiology is poorly understood, with controversial treatment and difficult to control in clinical practice.

    Objective: To evaluate the cases of recurrent aphthous ulcerations with a focus on treatment, diagnosis and etiology.

    Methods: This is a retrospective study of the cases of the Oral Diagnosis service of the Rio Grande do Norte Federal University in Natal/RN. Read More

    Presence of Candida spp. and candidiasis in liver transplant patients.
    An Bras Dermatol 2018 Jun;93(3):356-361
    Department of Clinical and Surgical Nursing, Escola Paulista de Enfermagem, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
    Background: Candidiasis is the most common opportunistic fungal infection of the oral cavity caused by fungi of the genus Candida and usually associated with immunosuppressed individuals.

    Objectives: To evaluate the presence of oral candidiasis and identify the presence of Candida spp. in liver transplant recipients and assess the association between the presence of the fungus and sociodemographic variables, dietary habits and environmental exposure. Read More

    Case for diagnosis. Erythroderma as manifestation of hypereosinophilic syndrome.
    An Bras Dermatol 2018 Jun;93(3):451-453
    Department of Dermatology, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, SP, Brazil.
    Hypereosinophilic syndrome is defined as persistent eosinophilia (>1500/µL for more than six months) associated with organ involvement, excluding secondary causes. It is a rare, potentially lethal disease that should be considered in cutaneous conditions associated with hypereosinophilia. We report a case of erythroderma as a manifestation of hypereosinophilic syndrome. Read More

    Dacryocystitis due to sporothrix inoculated vis an unusual mode: Case report.
    Medicine (Baltimore) 2018 Jun;97(25):e11182
    Department of Pathology, Second Hospital of Jilin University, Jilin University, Changchun, Jilin, P.R. China.
    Rationale: Sporotrichosis is the most common subcutaneous mycosis. It is caused by the dimorphic fungus Sporothrix schenckii. Ocular sporotrichosis is uncommon and has been rarely reported. Read More

    Usefulness of tocilizumab for treating rheumatoid arthritis with myelodysplastic syndrome: A case report and literature review.
    Medicine (Baltimore) 2018 Jun;97(25):e11179
    Department of Rheumatology.
    Rationale: Dysregulated immune function in rheumatoid arthritis (RA) might lead to the development of myelodysplastic syndrome (MDS). Serum interleukin-6 (IL-6) concentrations are increased in both RA and MDS patients.

    Patient Concerns: A 58-year-old woman presented with severe RA. Read More

    Unexpected and durable response with regorafenib in a metastatic colorectal cancer patient without KDR mutation: A case report.
    Medicine (Baltimore) 2018 Jun;97(25):e11178
    Medical Oncology Unit, S Carlo Hospital, Potenza.
    Rationale: Regorafenib is an oral multikinase inhibitor and is approved as salvage therapy in the standard treatment of advanced colorectal cancer (CRC). Due to its limited efficacy, toxicity profile, and cost, it is necessary to identify those patients who may have the most benefit from regorafenib. In a previous case report, kinase insert domain receptor (KDR) mutation has been associated with exceptional clinical response (CR) in an elderly patient treated with a low dose of regorafenib; thus, it was hypothesized that it could represent a new predictive marker of drug response. Read More

    Case report: successful treatment of refractory SAPHO syndrome with the JAK inhibitor tofacitinib.
    Medicine (Baltimore) 2018 Jun;97(25):e11149
    Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China.
    Introduction: Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is an autoinflammatory disorder without standardized treatment. Janus kinase (JAK) inhibitors can block a range of cytokines and might possess significant anti-inflammatory activity. Here, we report the first case of efficacious treatment of refractory SAPHO syndrome with the JAK inhibitor tofacitinib. Read More

    Cutaneous mucormycosis caused by Rhizopus microsporus in an immunocompetent patient: A case report and review of literature.
    Medicine (Baltimore) 2018 Jun;97(25):e11141
    Department of Dermatology.
    Rationale: Cutaneous mucormycosis is an uncommon disease and occurs rarely in immunocompetent patients.

    Patient Concerns: We reported the case of a 37-year-old man presenting with a skin lesion on the left side of the chest wall with no history of trauma or primary diseases. He was firstly misdiagnosed as tuberculosis and the proper treatment was thus delayed. Read More

    Euglycemic diabetic ketoacidosis caused by dapagliflozin: A case report.
    Medicine (Baltimore) 2018 Jun;97(25):e11056
    Department of Emergency Medicine, Chang Gung Memorial Hospital, Linkou.
    Rationale: Diabetic ketoacidosis is a serious and potentially life-threatening acute complication of diabetes mellitus (DM). Euglycemic diabetic ketoacidosis (eDKA) is however challenging to identify in the emergency department (ED) due to absence of marked hyperglycemia, often leading to delayed diagnosis and treatment. eDKA has been recently found to be associated with sodium-glucose cotransporter 2 (SGLT2) inhibitors, one of the newest classes of antidiabetics, though there are very limited reports implicating dapagliflozin as the offending agent in ED patients. Read More

    Steroid Withdrawal Effects Following Long-term Topical Corticosteroid Use.
    Dermatitis 2018 Jun 19. Epub 2018 Jun 19.
    From the Royal Randwick Medical Centre, New South Wales, Australia.
    Background: Concerns about topical steroid withdrawal (TSW) are leading some patients to cease long-term topical corticosteroid (TCS) therapy. Diagnostic criteria for this condition do not exist.

    Objective: The aim of this study was to examine the demographics and outcomes in adult patients who believe they are experiencing TSW following discontinuation of chronic TCS overuse. Read More

    Technical complications following implant-supported restorative therapy performed in Sweden.
    Clin Oral Implants Res 2018 Jun 20. Epub 2018 Jun 20.
    Department of Periodontology, Institute of Odontology, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
    Objective: The aim of this study was to evaluate the occurrence and consequences of technical complications in implant-supported restorative therapy.

    Material & Methods: The occurrence and consequences of technical complications in implant-supported restorative therapy over a mean follow-up period of 5.3 years were assessed based on documentation in files from 2,666 patients. Read More

    Donepezil for dementia due to Alzheimer's disease.
    Cochrane Database Syst Rev 2018 Jun 18;6:CD001190. Epub 2018 Jun 18.
    Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Botnar Research Centre, Windmill Road, Oxford, UK, OX3 7LD.
    Background: Alzheimer's disease is the most common cause of dementia in older people. One approach to symptomatic treatment of Alzheimer's disease is to enhance cholinergic neurotransmission in the brain by blocking the action of the enzyme responsible for the breakdown of the neurotransmitter acetylcholine. This can be done by a group of drugs known as cholinesterase inhibitors. Read More

    Management of Airway Obstruction in Infants With Pierre Robin Sequence.
    Plast Reconstr Surg Glob Open 2018 May 10;6(5):e1688. Epub 2018 May 10.
    Division of Plastic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.
    Background: Pierre Robin sequence (PRS)-related airway obstruction is often treated surgically; however, objective measures predicting the need for surgery are poorly defined.

    Methods: A retrospective chart review was performed on 171 neonates with PRS. Infants were grouped based upon intervention modality: nonsurgical (conservative) or surgical [mandibular distraction osteogenesis (MDO) or tracheostomy]. Read More

    Rare case of bilateral complex odontoma associated with mandibular bicuspids.
    Dent Res J (Isfahan) 2018 May-Jun;15(3):220-223
    Department of Oral Pathology, Thai Moogambigai Dental College and Hospital, Chennai, Tamil Nadu, India.
    Among oral pathologic lesions, odontomas are the most common odontogenic tumor of the jaws and generally asymptomatic. They are mostly diagnosed as a result of routine radiographic investigation. In this report, we describe a very rare occurrence of bilateral complex odontoma in the region of the mandibular second premolar. Read More

    Detection of leukotoxin and fimbria-associated protein gene genotypes among periodontitis patients and healthy controls: A case-control study.
    Dent Res J (Isfahan) 2018 May-Jun;15(3):185-190
    Department of Periodontics and Implantology, Sree Balaji Dental College and Hospital, Bharath Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
    Background: has been reported in higher proportions in subgingival microbiota of individuals with aggressive periodontitis (AgP) compared with those with chronic periodontitis (ChP) and healthy controls. The major virulence factors are the ones that help in colonization and evasion of host's defenses. Hence, this study was aimed to assess the prevalence of and its virulent genotypes (leukotoxin [] and fimbria-associated protein []). Read More

    A systematic literature review of the clinical and health economic burden of schizophrenia in privately insured patients in the United States.
    Clinicoecon Outcomes Res 2018 8;10:309-320. Epub 2018 Jun 8.
    Janssen Scientific Affairs, LLC, Titusville, NJ, USA.
    Purpose: The aim of this study was to conduct a systematic literature review on the burden of schizophrenia in privately insured US patients.

    Materials And Methods: A systematic literature review of English language peer-reviewed journal articles of observational studies published from 2006 to 2016 was conducted using EMBASE/MEDLINE databases. Abstracts covering substantial numbers of patients with schizophrenia or schizoaffective disorder (i. Read More

    Diagnosis and follow-up of type 2 diabetes in women with PCOS. A role of OGTT?
    Eur J Endocrinol 2018 Jun 19. Epub 2018 Jun 19.
    D Glintborg, Endocrinology, Odense University Hospital, Odense , DK-5000, Denmark.
    Polycystic ovary syndrome (PCOS) is common in premenopausal women. The majority of women with PCOS have insulin resistance and the risk of type 2 diabetes mellitus (T2D) is higher in women with PCOS compared to controls. In non-pregnant women with PCOS, glycemic status may be assessed by oral glucose tolerance test (OGTT), fasting plasma glucose (FPG), or HbA1c. Read More

    Pancreatitis and Systemic Coronavirus Infection in a Ferret ().
    Comp Med 2018 Jun;68(3):208-211
    Departments of Pathobiology, Ontario Veterinary College, University of Guelph, Ontario, Canada.
    A 1-y-old spayed female ferret (Mustela putorius furo) was referred for additional diagnostic evaluation after physical examination by the referring veterinarian revealed a cranial abdominal mass. The ferret had a 2-wk history of inappetence, weight loss, and lethargy. On presentation, the ferret was thin, and an approximately 3-cm mass was palpable in the cranial abdomen. Read More

    Distribution of biopsied non plaque-induced gingival lesions in a Chilean population according to the classification of periodontal diseases.
    BMC Oral Health 2018 Jun 19;18(1):112. Epub 2018 Jun 19.
    Department of Pathology, Faculty of Dentistry, University of Chile, Sergio Livingstone 943, Independencia, Santiago, Chile.
    Background: Many gingival lesions are not induced by plaque. The aim of this study was to analyze the frequency of biopsied non-plaque-induced gingival lesions (NPIGL) in a Chilean population.

    Methods: One thousand twelve cases of biopsied gingival lesions with confirmed anatomopathologic diagnosis were included, from the records of the Oral Pathology Referral Institute (OPRI), Faculty of Dentistry, University of Chile, between years 1990 and 2009. Read More

    A clinical and radiological long-term follow-up study of narrow diameter implants in the aesthetic area.
    Clin Implant Dent Relat Res 2018 Jun 19. Epub 2018 Jun 19.
    Department of Surgical Sciences, Plastic & Oral and Maxillofacial Surgery, Uppsala University, Uppsala SE-751 85, Sweden.
    Purpose: To study long-term function of narrow diameter implants (NDI:s) and if reduced implant-tooth distance negatively impacts adjacent teeth.

    Materials And Methods: A clinical and radiological follow-up of NDI:s replacing maxillary laterals and mandibular incisors was performed. Subjects that received 3. Read More

    Clinical features and outcomes of hepatocellular carcinoma in Caucasian cirrhotic patients on long-term analogue therapy for hepatitis B.
    Aliment Pharmacol Ther 2018 Jun 19. Epub 2018 Jun 19.
    CRC "A.M. e A. Migliavacca" Center for the Study of Liver Disease, Division of Gastroenterology and Hepatology, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, Milan, Italy.
    Background: Long-term oral nucleos(t)ide analogue (NUC) therapy in hepatitis B virus (HBV)-related compensated cirrhotics prevents clinical decompensation but not hepatocellular carcinoma (HCC) development.

    Aims: To define the clinical features and outcomes of HCC in long-term NUC-treated HBV patients.

    Methods: All HCCs developing between 2005 and 2016 in NUC-treated HBV patients under surveillance were studied, excluding those that occurred within the first 6 months of therapy. Read More

    Clinicopathological analysis of oral plasmablastic lymphoma: A systematic review.
    J Oral Pathol Med 2018 Jun 19. Epub 2018 Jun 19.
    Department of Oral Diagnosis Piracicaba Dental School, University of Campinas, Piracicaba, Brazil.
    Background: Plasmablastic lymphoma (PBL) is a high grade lymphoma that often affects the oral cavity of HIV-positive patients; however, its prognostic determinants remain unknown.

    Purpose: To integrate the available data on oral PBL to determine its clinico-pathological features and to identify potential prognostic factors.

    Methods: An electronic systematic review was performed using multiple databases with a specific search strategy in February 2018. Read More

    Acute Glaucoma Following Cyanoacrylate Glue Patch for Corneal Perforation.
    J Glaucoma 2018 Jun 18. Epub 2018 Jun 18.
    Moorfields Eye Hospital, NHS Foundation Trust, London, UK.
    Purpose: To describe a case of acute glaucoma after cyanoacrylate gluing for a non-traumatic central corneal perforation.

    Methods: A 55-year-old woman with history of rheumatoid arthritis and severe dry eye presented to emergency with a right central corneal perforation. She was treated successfully with the use cyanoacrylate glue patch but iridocorneal adhesions remained. Read More

    Oral health-related quality of life in patients under supportive periodontal therapy.
    Acta Odontol Scand 2018 Jun 19:1-8. Epub 2018 Jun 19.
    a Section of Periodontology, Department of Conservative Dentistry, Clinic for Oral, Dental and Maxillofacial Diseases , University Hospital Heidelberg , Heidelberg , Germany.
    Objective: To assess the oral health-related quality of life (OH-QoL) in patients under supportive periodontal therapy (SPT) and the influence of the individual periodontal risk as well as different degrees of adherence during SPT on OH-QoL.

    Materials And Methods: 309 patients with at least 5 years of SPT were re-examined. Periodontal risk profile (according to Lang and Tonetti) was assessed and the adherence to SPT-appointments within the last 30(±6) months was reviewed for each patient (fully adherent: adherence to all appointments ±6 weeks, partially adherent: SPT-interval not extended more than half of the recommended interval, insufficiently adherent: SPT-interval extended more than half of the recommended interval, non-adherent: recommended SPT-interval interruption ≥12 months). Read More

    Association of risk factors with temporomandibular disorders in the Northern Finland Birth Cohort 1966.
    Acta Odontol Scand 2018 Jun 19:1-5. Epub 2018 Jun 19.
    a Research Unit of Oral Health Sciences, Faculty of Medicine , University of Oulu , Oulu , Finland.
    Objective: To investigate the association between risk factors and pain-related symptoms and clinical signs of temporomandibular disorders (TMD) in Northern Finland Birth Cohort (NFBC) 1966.

    Material And Methods: A total of 1962 subjects (1050 women, 912 men) attended the follow-up study. The questionnaires included the subjects' background information concerning living conditions and general health, socioeconomic factors, and dental health. Read More

    Influence of acquisition parameters on the magnitude of cone beam computed tomography artifacts.
    Dentomaxillofac Radiol 2018 Jun 19:20180151. Epub 2018 Jun 19.
    3 Department of Comprehensive Dentistry, Division of Oral and Maxillofacial Radiology, University of Texas Health Science Center at San Antonio , San Antonio, TX , United States.
    Aim: To evaluate the influence of kilovoltage (kVp) and metal artefact reduction tool (MAR) on the magnitude of cone beam computed tomography (CBCT) artifacts.

    Methods: A titanium and zirconia implants were inserted alternately in a posterior region of a mandible. CBCT exams were acquired with ProMax 3D (Planmeca Oy, Helsinki, Finland) and Picasso Trio machines (Vatech, Hwaseong, South Korea) using 70 kVp, 80 kVp and 90 kVp with and without MAR activation. Read More

    Salivary cytokine panel indicative of non-small cell lung cancer.
    J Int Med Res 2018 Jan 1:300060518775563. Epub 2018 Jan 1.
    3 Shinshu University, Graduate School of Science & Technology, Department of Mechanical Engineering & Robotics, Tokida, Ueda, Nagano, Japan.
    Objective To develop a combinatorial panel of salivary cytokines that manifests the presence of non-small cell lung cancer (NSCLC) that will eventually improve prognosis by facilitating the early diagnosis and management of this common cancer. Methods We performed a case-control study comparing salivary cytokine profiles of 35 adult subjects with NSCLC with those of 35 matched, healthy nonsmokers. Multiplex bead array assays were used to quantify 27 cytokines in saliva, serum, and oral mucosal transudate samples. Read More

    Effect of phosphodiesterase-5 inhibition on joint and muscle damage in rats with adjuvant arthritis
    Turk J Med Sci 2018 Jun 14;48(3):635-643. Epub 2018 Jun 14.
    Background/aim: This study was designed to examine the effect of tadalafil, a phosphodiesterase (PDE)5 inhibitor, on the severity of joint and muscle damage in rats with adjuvant-induced arthritis (AA). Materials and methods: AA was induced by intradermal inoculation into right hind paw of male Sprague Dawley rats (300-450g) with complete Freund's adjuvant (CFA; 0.1 mL). Read More

    Anticoagulation in non-malignant portal vein thrombosis is safe and improves hepatic function.
    Wien Klin Wochenschr 2018 Jun 18. Epub 2018 Jun 18.
    Vienna Hepatic Hemodynamic Lab, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria.
    Background: Non-malignant portal vein thrombosis (PVT) is common in patients with advanced liver disease. Anticoagulation (AC) increases the chances of recanalization and may improve liver function in patients with cirrhosis.

    Aim: We retrospectively assessed the course of non-malignant PVT in patients receiving AC. Read More

    Mimicking Subacute Appendicitis.
    Gastroenterology Res 2018 Jun 31;11(3):235-237. Epub 2018 May 31.
    Department of Internal Medicine, Bassett Medical Center, Cooperstown, NY, USA.
    () infection in humans is uncommon in the United States. Although there has been a drastic decline in the report of infection in this region, physicians should be aware of an uncommon presentation and its clinical relevance. We report a case of 55-year-old female of Ecuadorian/Peruvian origin who presented with an unknown cause of chronic right lower quadrant abdominal pain for 2 months without other particular symptoms. Read More

    Cryptosporidiosis: A zoonotic disease concern.
    Vet World 2018 May 23;11(5):681-686. Epub 2018 May 23.
    One Health Research Unit, Faculty of Veterinary Sciences, Mahasarakham University, Maha Sarakham, Thailand.
    Cryptosporidiosis is considered to be a crucial zoonotic disease caused by worldwide distributing parasitic protozoa called spp. Cryptosporidiosis becomes a major public health and veterinary concern by affecting in human and various host range species of animals. Essentially, its importance of infection is increasing because of the high incidence in young children, immunocompromised persons, or immunodeficiency syndrome patients, especially in HIV/AIDS, and it is also one of the most causes of mortality in those patients who infected with spp. Read More

    A linear plasmid-like prophage of Promotes Biofilm Assembly.
    Appl Environ Microbiol 2018 Jun 18. Epub 2018 Jun 18.
    The Forsyth Institute, Cambridge, USA
    The human oral cavity is home to a large number of bacteria and bacteriophages (phages). However, the biology of oral phages as members of the human microbiome is not well understood. Recently, we isolated an subsp. Read More

    Future Prospects for Treatment.
    Antibiotics (Basel) 2018 Jun 15;7(2). Epub 2018 Jun 15.
    Área de Microbiología, Departamento de Farmacia, Instituto de Ciencias Biomédicas, Facultad de Ciencias de la Salud, Universidad CEU Cardenal Herrera, C/Santiago Ramón y Cajal, 46115 Alfara del Patriarca, Valencia, Spain.
    Gonorrhea is a sexually transmitted disease with a high morbidity burden. Incidence of this disease is rising due to the increasing number of antibiotic-resistant strains. has shown an extraordinary ability to develop resistance to all antimicrobials introduced for its treatment. Read More

    Hospitalization after Oral Antibiotic Initiation in Finnish Community Dwellers with and without Alzheimer's Disease: Retrospective Register-Based Cohort Study.
    J Alzheimers Dis 2018 Jun 8. Epub 2018 Jun 8.
    School of Pharmacy, University of Eastern Finland, Kuopio, Finland.
    Background: Persons with Alzheimer's disease (AD) are frequently hospitalized from infection-related causes. There are no previous studies investigating hospitalization associated with antibiotic initiation in persons with AD.

    Objective: To investigate the frequency and risk of hospitalization associated with oral antibiotic initiation among community dwellers with and without AD. Read More

    Difficult diagnosis of facial pain: A case report and mini-review.
    Scand J Pain 2017 Dec 29;1(4):179-183. Epub 2017 Dec 29.
    Department of Radiology, Turku University Hospital, Turku, Finland.
    This case report elucidates pitfalls of clinical and radiologic investigations of neuropathic pain due to trigeminal pathology, and utility of neurophysiologic examination when diagnosing facial pain. Our patient was a 63-year-old woman who developed acute, severe facial pain, first located behind the left eye. Neuralgic exacerbations, paresthesia within lower face on the left and restricted mouth opening occurred during the course of the disease with gradual progression. Read More

    Ocular findings in MELAS syndrome – a case report.
    Klin Oczna 2016;118(4):301-7
    We present a case of a child with MELAS syndrome (mitochondrial encephalo-myopathy with lactic acidosis and stroke-like episodes), discussing clinical manifestation, ocular findings and diagnostic challenges. Predominant ocular symptom was a transient complete visual loss, while the predominant ocular sign was a visual field defect. The diagnosia was based on clinical manifestation, laboratory tests, brain scans and genetic testing which confirmed the pathognomonic mutation in the MTTL1 gene encoding the mitochondrial tRNA for leucine 3243> G. Read More

    Perioperative Anaphylaxis Including Kounis Syndrome due to Selective Cefazolin Allergy.
    Int Arch Allergy Immunol 2018 Jun 18:1-5. Epub 2018 Jun 18.
    Background: Perioperative use of cefazolin has been associated with severe allergic reactions, and patients are usually labelled as allergic to penicillin afterwards. The aim of our study was to describe a group of patients with immediate reactions to cefazolin, with proven selective hypersensitivity reactions.

    Methods: Systematic review of all patients followed at our drug centre with cefazolin-related reactions, between January 2012 and December 2016. Read More

    Five-decade-delayed closed flexor tendon rupture due to Galeazzi dislocation fracture associated with Behçet syndrome: A case report.
    Int J Surg Case Rep 2018 May 29;48:87-91. Epub 2018 May 29.
    Department of Orthopedics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, 602-8566, Kyoto, Japan.
    Introduction: Closed flexor tendon rupture after a malunited distal radius fracture is rare and usually becomes apparent early after the fracture. Most cases are accompanied by a severe distal radio-ulnar joint capsule injury, wherein bone protrusion (as a spur) directly stresses the tendons. We experienced a nonspecific flexor tendon rupture associated with an old fracture and the presence of collagen disease. Read More

    Recent Advances in the Etiology and Treatment of Burning Mouth Syndrome.
    J Dent Res 2018 Jun 1:22034518782462. Epub 2018 Jun 1.
    2 Department of Oral Biology, School of Dental Medicine, State University of New York at Buffalo, Buffalo, NY, USA.
    Burning mouth syndrome (BMS) is a debilitating condition that has a striking female predilection. Although the oral mucosa is normal in appearance, patients with BMS experience oral burning that most commonly localizes to the lips and tongue. BMS is a diagnosis of exclusion, and all underlying pathoses associated with allodynia must be ruled out prior to rendering the diagnosis. Read More

    Laser Pointer-Induced Maculopathy: More Than Meets the Eye.
    J Pediatr Ophthalmol Strabismus 2018 Jun 18:1-7. Epub 2018 Jun 18.
    Purpose: To describe the clinical findings in patients with laser-induced retinal injury.

    Methods: Consecutive patients presenting to a tertiary center between January 2014 and December 2015 following inadvertent ocular exposure to a laser pointer were included. Evaluation included a full ophthalmic examination and spectral-domain optical coherence tomography (SD-OCT). Read More

    Oral and Otorhinolaryngological Findings in Adults Who Were Diagnosed With Pediatric Onset Crohn's Disease: A Controlled Study.
    J Clin Gastroenterol 2018 Jun 16. Epub 2018 Jun 16.
    Childrens Hospital.
    Background: Up to 50% of pediatric patients with Crohn's disease (CD) report oral manifestations, but less is known about their oral health when they become adults.

    Goals: Our aim was to provide detailed descriptions of the presence of oral and otorhinolaryngological manifestations in patients with pediatric onset CD once they reached adulthood, to look for predisposing factors and to compare the findings to matched controls.

    Study: Adult patients diagnosed with CD in childhood at the Children's Hospital, University of Helsinki, Finland, after 2000 were invited for a follow-up appointment in 2016 and 24 were examined by a dentist and otorhinolaryngologist. Read More

    Deep Artificial Neural Networks for the Diagnostic of Caries Using Socioeconomic and Nutritional Features as Determinants: Data from NHANES 2013⁻2014.
    Bioengineering (Basel) 2018 Jun 18;5(2). Epub 2018 Jun 18.
    Unidad Académica de Ingeniería Eléctrica, Universidad Autónoma de Zacatecas, Jardín Juarez 147, Centro, Zacatecas 98000, Zac, México.
    Oral health represents an essential component in the quality of life of people, being a determinant factor in general health since it may affect the risk of suffering other conditions, such as chronic diseases. Oral diseases have become one of the main public health problems, where dental caries is the condition that most affects oral health worldwide, occurring in about 90% of the global population. This condition has been considered a challenge because of its high prevalence, besides being a chronic but preventable disease which can be caused depending on the consumption of certain nutritional elements interacting simultaneously with different factors, such as socioeconomic factors. Read More

    Oral and dental anomalies in purebred, brachycephalic Persian and Exotic cats.
    J Am Vet Med Assoc 2018 Jul;253(1):66-72
    OBJECTIVE To determine the prevalence of dental anomalies in brachycephalic cats from various geographic regions and analyze potential relationships with oral disease. DESIGN Prospective multicenter cross-sectional study. ANIMALS 50 purebred Persian (n = 42) and Exotic (8) cats. Read More

    Vitamin D Supplementation Seems to Improve Fibromyalgia Symptoms: Preliminary Results.
    Isr Med Assoc J 2018 Jun;20(6):379-381
    Background: Vitamin D deficiency and insufficiency have been reported in fibromyalgia. However, to the best of our knowledge, only one study has evaluated the role of 25-hydroxyvitamin D [25(OH)D] supplementation on fibromyalgia symptoms.

    Objectives: To analyze the effects of 3 months of 25(OH)D supplementation on symptoms of fibromyalgia. Read More

    The Prevalence of Folliculitis in Patients with Papulopustular/Comedonal Acne, and Their Response to Antifungal Treatment.
    Skinmed 2018 1;16(2):99-104. Epub 2018 Apr 1.
    Department of Dermatology, Baskent University Faculty of Medicine, Ankara, Turkey.
    Because folliculitis (MF) may clinically mimic acne vulgaris (AV), patients usually receive unnecessary and prolonged antibiotic treatment. We aimed to determine the prevalence of MF among patients with AV, and to evaluate its response to antifungal treatment. A total of 217 patients with AV underwent cytologic examination for the presence of yeasts. Read More

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