9 results match your criteria Open Journal of Ophthalmology

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Measuring optic nerve head perfusion to monitor glaucoma: a study on structure-function relationships using laser speckle flowgraphy.

Acta Ophthalmol 2021 Apr 20. Epub 2021 Apr 20.

Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.

Purpose: We aimed to describe the global and localized correlations among visual field (VF) sensitivity, optic nerve head (ONH) perfusion measured by laser speckle flowgraphy (LSFG) and neural structure measured by optical coherence tomography (OCT) in open-angle glaucoma (OAG) and to compare the floor effect for LSFG and OCT.

Methods: Cross-sectional, multicenter study including one eye each from fifty OAG patients (mean age 69.3 years; average VF mean deviation, MD, -8. Read More

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Predictive Analytics for Glaucoma Using Data From the All of Us Research Program.

Am J Ophthalmol 2021 Jan 23;227:74-86. Epub 2021 Jan 23.

UCSD Health Department of Biomedical Informatics, University of California San Diego, (S.L.B., B.R.S., P.P., J.K., L.B., T.-T.K., L.O.-M.), La Jolla, California; Division of Health Services Research and Development, Veterans Affairs San Diego Healthcare System, La Jolla, California (L.O.-M.), USA.

Purpose: To (1) use All of Us (AoU) data to validate a previously published single-center model predicting the need for surgery among individuals with glaucoma, (2) train new models using AoU data, and (3) share insights regarding this novel data source for ophthalmic research.

Design: Development and evaluation of machine learning models.

Methods: Electronic health record data were extracted from AoU for 1,231 adults diagnosed with primary open-angle glaucoma. Read More

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January 2021

Monthly Intravitreal Infliximab in Behçet's Disease Active Posterior Uveitis: A Long-Term Safety Study.

Retina 2020 Dec 28;Publish Ahead of Print. Epub 2020 Dec 28.

Department of Ophthalmology Department of Internal Medicine, Kasr El Aini Hospital, Cairo University, El-Manial, Cairo, Egypt.

Purpose: To study the safety of extended monthly intravitreal infliximab injections in patients with active posterior uveitis in Behcet's disease (APUBD).

Methods: This is a prospective, interventional, noncomparative, open-label, pilot study of 9 monthly intravitreal infliximab injections (1mg/0.05ml) for twenty-two eyes of 16 patients with APUBD. Read More

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December 2020

Central Visual Field Sensitivity with and without Background Light Given to the Non-tested Fellow Eye in Glaucoma Patients.

J Glaucoma 2020 Dec 21;Publish Ahead of Print. Epub 2020 Dec 21.

Department of Ophthalmology, Saitama Medical University, Saitama, Japan.

Precis: This study showed the difference of monocular visual sensitivity between with and without background light given to the non-tested fellow eyes in glaucoma patients. Monocular sensitivity measurements of the worse eyes with fellow eye's background light conditions should carefully be considered when assessing the impact of functional impairment in glaucoma patients.

Purpose: To investigate the difference between monocular sensitivities measured with and without background light given to the non-tested fellow eye in glaucoma patients using a new perimeter named "imo. Read More

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December 2020

Optical Quality in Keratoconus Is Associated With Corneal Biomechanics.

Cornea 2020 Dec 16;Publish Ahead of Print. Epub 2020 Dec 16.

Department of Ophthalmology, Osaka University Graduate School of Medicine, Osaka, Japan; Department of Innovative Visual Science, Osaka University Graduate School of Medicine, Osaka, Japan; Seed Co, Ltd, Tokyo, Japan; Instituto de Olhos Renato Ambrósio/Visare Personal Laser, and Department of Ophthalmology, Federal University of the State of Rio de Janeiro (UNIRIO), Rio de Janeiro, Brazil; and Life and Medical Science Frontier Research Division, Institute for Open and Transdisciplinary Research Initiatives, Osaka University Graduate School of Medicine, Osaka, Japan.

Purpose: To evaluate the correlations between corneal biomechanical indices from dynamic Scheimpflug assessment and optical quality assessed as higher-order aberrations (HOAs) using a Hartmann-Shack ocular wavefront sensor in patients with keratoconus (KC).

Methods: In this prospective, observational case series, the eyes with KC or KC suspect (KCS) from Osaka University Hospital, Osaka, Japan, were analyzed. Corneal biomechanical assessment was performed using Corvis ST (Oculus Optikgeräte GmbH, Wetzlar, Germany), and ocular wavefront aberrations were measured using the KR-1W (Topcon Corp, Tokyo, Japan). Read More

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December 2020

Understanding Retinal Changes after Stroke.

Authors:
Varun Kumar

Open J Ophthalmol 2017 Nov 6;7(4):281-292. Epub 2017 Nov 6.

Department of Ophthalmology, School of Medicine, Stanford University, Stanford, CA, USA.

Stroke is the fifth leading cause of death and disability in the United States. According to World Heart Federation, every year, 15 million people suffer from stroke worldwide out of which nearly 6 million people die and another 5 million people are disabled. Out of many organs affected after stroke, one of them is eye. Read More

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November 2017

Novel Mechanistic Interplay between Products of Oxidative Stress and Components of the Complement System in AMD Pathogenesis.

Open J Ophthalmol 2016 Feb 26;6(1):43-50. Epub 2016 Feb 26.

Department of Ophthalmology and Shiley Eye Institute, University of California San Diego, San Diego, USA.

Age-related macular degeneration (AMD) is a leading cause of vision loss affecting tens of millions of elderly worldwide. Early AMD includes soft drusen and pigmentary changes in the retinal pigment epithelium (RPE). As people age, such soft confluent drusen can progress into two forms of advanced AMD, geographic atrophy (GA, or dry AMD) or choroidal neovascularization (CNV, or wet AMD) and result in the loss of central vision. Read More

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February 2016

Pseudophacomorphic Glaucoma along with Pupillary Block after Visian™ Implantable Collamer Lens Implantation for High Myopia.

Open J Ophthalmol 2014 Nov;4(4):107-111

Francis I. Proctor Foundation, University of California San Francisco, San Francisco, USA.

Purpose: To report a case of bilateral glaucoma related to pseudophacomorphic mechanism in one eye and pupillary block in the other eye after Visian Implantable Collamer Lens (ICL, STAAR Surgical) insertion.

Methods: A 44 year-old female with high myopia underwent bilateral ICL implantation of MICL12.6 after sulcus diameter measurements were performed by Pentacam. Read More

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November 2014

MRI findings in Post-operative Bilateral Posterior Ischemic Optic Neuropathy.

Open J Ophthalmol 2013 ;3:51-53

Department of Ophthalmology and Visual Sciences, University of Maryland School of Medicine, Baltimore MD USA.

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January 2013
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