9 results match your criteria Open Journal of Animal Sciences

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Antidepressant Effect of Intermittent Long-Term Systemic Administration of Irisin in Mice.

Int J Mol Sci 2022 Jul 8;23(14). Epub 2022 Jul 8.

Department of Emergency and Organ Transplantation, University of Bari, 70126 Bari, Italy.

Depression is a psychiatric disorder increasingly diffused worldwide. Evidence suggests that irisin, a myokine secreted by contracting muscle, mediates beneficial effects on several targets, including the brain. Here, the potential antidepressant properties of long-term intermittent systemic irisin administration (100 µg/kg/weekly for 1 month) were evaluated in mice by the Tail Suspension Test (TST), Forced Swim Test (FST), and Open Field Test (OFT). Read More

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BMP3 is a novel locus involved in the causality of ocular coloboma.

Hum Genet 2022 Aug 28;141(8):1385-1407. Epub 2022 Jan 28.

Department of Biological Sciences, University of Alberta, 11455 Saskatchewan Drive, Edmonton, AB, T6G 2E9, Canada.

Coloboma, a congenital disorder characterized by gaps in ocular tissues, is caused when the choroid fissure fails to close during embryonic development. Several loci have been associated with coloboma, but these represent less than 40% of those that are involved with this disease. Here, we describe a novel coloboma-causing locus, BMP3. Read More

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Selection and Validation of Reference Genes for Gene Expression Analysis in Meyrick (Lepidoptera: Gelechiidae).

Insects 2021 Jun 29;12(7). Epub 2021 Jun 29.

Guizhou Provincial Key Laboratory for Rare Animal and Economic Insect of the Mountainous Region, College of Biology and Environmental Engineering, Guiyang University, Guiyang 550005, China.

The tomato leaf miner, is a destructive pest of tomato. The leaf-mining activities of its larvae can cause significant yield losses. Real-time quantitative polymerase chain reaction (RT-qPCR) is commonly used to measure gene expression, and the selection of stable reference genes for calibration and standardization is critical for accurate use of RT-qPCR. Read More

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Chromosome-level genome assembly of the greenfin horse-faced filefish (Thamnaconus septentrionalis) using Oxford Nanopore PromethION sequencing and Hi-C technology.

Mol Ecol Resour 2020 Jul 9;20(4):1069-1079. Epub 2020 Jul 9.

Qingdao Municipal Ocean Technology Achievement Promotion Center, Qingdao, China.

The greenfin horse-faced filefish, Thamnaconus septentrionalis, is a valuable commercial fish species that is widely distributed in the Indo-West Pacific Ocean. This fish has characteristic blue-green fins, rough skin and a spine-like first dorsal fin. Thamnaconus septentrionalis is of conservation concern because its population has declined sharply, and it is an important marine aquaculture fish species in China. Read More

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A phylogenetic study of splicing assembly chaperone RNP-4F associated U4-/U6-snRNA secondary structure.

Open J Anim Sci 2013 Nov;3(48):36-48

Department of Biology, Cell Molecular and Structural Biology Program, Miami University, Oxford, USA.

The -4 gene in encodes nuclear protein RNP-4F. This encoded protein is represented by homologs in other eukaryotic species, where it has been shown to function as an intron splicing assembly factor. Here, RNP-4F is believed to initially bind to a recognition sequence on U6-snRNA, serving as a chaperone to facilitate its association with U4-snRNA by intermolecular hydrogen bonding. Read More

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November 2013

A molecular, phylogenetic and functional study of the mRNA truncated isoform during embryonic development reveals an editing-independent function.

Open J Anim Sci 2013 Nov;3(48):20-30

Department of Biology, Cell Molecular and Structural Biology Program, Miami University, Oxford, USA.

Adenosine Deaminases Acting on RNA (ADARs) have been studied in many animal phyla, where they have been shown to deaminate specific adenosines into inosines in duplex mRNA regions. In , two isoform classes are encoded, designated full-length (contains the editase domain) and truncated (lacks this domain). Much is known about the full-length isoform, which plays a major role in regulating functions of voltage-gated ion channel proteins in the adult brain. Read More

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November 2013

Treatment with melatonin after status epilepticus attenuates seizure activity and neuronal damage but does not prevent the disturbance in diurnal rhythms and behavioral alterations in spontaneously hypertensive rats in kainate model of temporal lobe epilepsy.

Epilepsy Behav 2014 Feb 16;31:198-208. Epub 2014 Jan 16.

Institute of Neurobiology, Acad. G. Bonchev Str., Bl. 23, Bulgarian Academy of Sciences, Sofia 1113, Bulgaria.

Melatonin is involved in the control of circadian and seasonal rhythmicity, possesses potent antioxidant activity, and exerts a neuroprotective and anticonvulsant effect. Spontaneously hypertensive rats (SHRs) are widely accepted as an experimental model of essential hypertension with hyperactivity, deficient sustained attention, and alterations in circadian autonomic profiles. The purpose of the present study was to determine whether melatonin treatment during epileptogenesis can prevent the deleterious consequences of status epilepticus (SE) in SHRs in the kainate (KA) model of temporal lobe of epilepsy (TLE). Read More

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February 2014

"Alas poor Yorick": What retrospective analysis of canine skulls can tell us about the impact of environmental factors on health.

Open J Anim Sci 2013 Jul;3(3A)

Department of Biology, University of Utah, Salt Lake City, USA.

Necropsies and extensive histological evaluation for clinical and sub-clinical disease of approximately three hundred Portuguese Water dogs are available as part of an ongoing study to assess their state of health at end of life. Throughout life these dogs enjoyed a variety of lifestyles and environments. Here we carry out retrospective quantitative assessments of life-time dietary input and physical activity for each dog. Read More

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Repeated administration of AC-5216, a ligand for the 18 kDa translocator protein, improves behavioral deficits in a mouse model of post-traumatic stress disorder.

Prog Neuropsychopharmacol Biol Psychiatry 2013 Aug 23;45:40-6. Epub 2013 Apr 23.

Department of Pharmacology, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou 510515, China.

Post-traumatic stress disorder (PTSD) is a severely disabling anxiety disorder that may occur following exposure to a serious traumatic event. It is a psychiatric condition that can afflict anyone who has experienced a life-threatening or violent event. Previous studies have shown that changes in 18 kDa translocator protein (TSPO) expression (or function), a promising target for treating neurological disorders without benzodiazepine-like side effects, may correlate with PTSD. Read More

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