711 results match your criteria Oophoritis

Xanthogranulomatous salpingo-oophoritis presenting as an ovarian tumour.

BMJ Case Rep 2022 May 19;15(5). Epub 2022 May 19.

Gynecology, Centro Hospitalar de Vila Nova de Gaia Espinho EPE, Vila Nova de Gaia, Portugal.

Xanthogranulomatous salpingo-oophoritis (XGSO) is an exceptionally rare entity. Its clinical manifestations and imaging modalities can mimic benign and malignant adnexal diseases, making it difficult to diagnose. Here we report a case of XGSO in a young woman who was operated with suspicion of a borderline ovarian tumour. Read More

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P450 Side-Chain Cleavage Enzyme (P450-SCC) Is an Ovarian Autoantigen in a Mouse Model for Autoimmune Oophoritis.

Reprod Sci 2022 May 18. Epub 2022 May 18.

Reproductive Biology and Medicine Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.

Steroid-producing cells contain key cytochrome P450 enzymes, such as side-chain cleavage (P450-SCC) and 17α-hydroxylase (17α-OH). They are required for steroid hormone synthesis and considered antigens associated with Addison's disease and autoimmune primary ovarian insufficiency (POI). We studied an animal model for human autoimmune POI in mice with autoimmune oophoritis induced by neonatal thymectomy performed at day 3 (TX3). Read More

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Maternal disease factors associated with neonatal jaundice: a case-control study.

BMC Pregnancy Childbirth 2022 Mar 24;22(1):247. Epub 2022 Mar 24.

Department of Biomedical Informatics, CHA University School of Medicine, CHA University, Seongnam, Korea.

Background: Neonatal jaundice is common, and despite the considerable medical costs associated with it, there are still few studies on the maternal factors associated with it. Identification of maternal factors associated with neonatal jaundice is very important in terms of prevention, screening and management of neonatal jaundice. The current study aimed to identify maternal disease factors associated with neonatal jaundice. Read More

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Wiad Lek 2022 ;75(1 pt 2):251-258


Objective: The aim: To obtain the first estimates of the current incidence, and risk factors for Surgical Site Infection (SSI) after laparoscopic hysterectomy, and antimicrobial resistance of responsible pathogens in Ukraine.

Patients And Methods: Materials and methods: We performed a multicenter prospective cohort study was patient-based on surveillance data for SSIs were according to CDC/NHSN methodology. This study included women's undergoing a laparoscopic hysterectomy in 8 hospitals from different regions of Ukraine from January 2018 to December 2020. Read More

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February 2022

[The 490th case: arthralgia, amenorrhea, aphasia].

Zhonghua Nei Ke Za Zhi 2021 Dec;60(12):1189-1192

Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, National Clinical Research Center for Dermatologic and Immunologic Diseases, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing 100730, China.

A 25-year-old woman was admitted to Peking Union Medical Hospital presented with arthralgia for 5 years, amenorrhea for 16 months, and speech disorder for 3 months. This patient has been afflicted by intermittent pain in metacarpophalangeal and proximal interphalangeal joints of both hands for 5 years. Her menstruation has been irregular 1 year ago and rapidly progressed to amenorrhea. Read More

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December 2021

Silkworm recombinant bovine zona pellucida protein 4 (bZP4) as a potential female immunocontraceptive antigen; impaired sperm-oocyte interaction and ovarian dysfunction.

J Reprod Dev 2021 Dec 21;67(6):402-406. Epub 2021 Oct 21.

Division of Silk-Producing Insect Biotechnology, Institute of Agrobiological Sciences, National Agriculture and Food Research Organization (NARO), Ibaraki 305-8634, Japan.

Porcine zona pellucida proteins (ZPs) have been utilized as female immunocontraceptive antigens. The purpose of this study was to explore the potential use of silkworm recombinant bovine ZP4 as an alternative. When the protein was injected with monophosphoryl lipid A (MPL) - an immuno-stimulative agent - into two female goats, marked elevation of the anti-ZP4 titer was detected. Read More

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December 2021

a novel opportunistic pathogen in poultry.

Avian Pathol 2022 Feb 19;51(1):26-33. Epub 2022 Jan 19.

Department of Poultry Diseases with Clinic, Faculty of Veterinary Medicine, University of Zagreb, Zagreb, Croatia.

[H. Kurth, 1883. Ueber , eine neue Bakterienart. Read More

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February 2022

Unique Tropism and Entry Mechanism of Mumps Virus.

Viruses 2021 09 1;13(9). Epub 2021 Sep 1.

Laboratory of Medical Virology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.

Mumps virus (MuV) is an important human pathogen that causes parotitis, orchitis, oophoritis, meningitis, encephalitis, and sensorineural hearing loss. Although mumps is a vaccine-preventable disease, sporadic outbreaks have occurred worldwide, even in highly vaccinated populations. MuV not only causes systemic infection but also has a unique tropism to glandular tissues and the central nervous system. Read More

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September 2021

Cross-Serovar Protection during Experimental Lung Reinfection in Mice.

Vaccines (Basel) 2021 Aug 6;9(8). Epub 2021 Aug 6.

Institute of Medical Microbiology and Hospital Epidemiology, Medical School Hannover, 30625 Hannover, Germany.

causes most bacterial sexually transmitted diseases worldwide. Different major outer membrane proteins (MOMPs) define various serovars of this intracellular pathogen: In women, D to L3 can cause urethritis, cervicitis, salpingitis, and oophoritis, and, thus, infertility. Protective immunity might be serovar-specific since chlamydial infection does not appear to induce an effective acquired immunity and reinfections occur. Read More

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Gonococcal Pelvic Inflammatory Disease: Placing Mechanistic Insights Into the Context of Clinical and Epidemiological Observations.

J Infect Dis 2021 08;224(12 Suppl 2):S56-S63

Department of Molecular Genetics, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.

While infection by Neisseria gonorrhoeae is often asymptomatic in women, undetected infections can ascend into the upper genital tract to elicit an inflammatory response that manifests as pelvic inflammatory disease, with the outcomes depending on the intensity and duration of inflammation and whether it is localized to the endometrial, fallopian tube, ovarian, and/or other tissues. This review examines the contribution of N. gonorrhoeae versus other potential causes of pelvic inflammatory disease by considering new insights gained through molecular, immunological, and microbiome-based analyses, and the current epidemiological burden of infection, with an aim to highlighting key areas for future study. Read More

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Prophylactic Multi-Subunit Vaccine against In Vivo Evaluation in Mice.

Vaccines (Basel) 2021 Jun 6;9(6). Epub 2021 Jun 6.

Institute of Medical Microbiology and Hospital Epidemiology, Medical School Hannover, 30625 Hannover, Germany.

is the most frequent sexually-transmitted disease-causing bacterium. Urogenital serovars of this intracellular pathogen lead to urethritis and cervicitis. Ascending infections result in pelvic inflammatory disease, salpingitis, and oophoritis. Read More

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Report of two siblings with APECED in Serbia: is there a founder effect of c.769C>T AIRE genotype?

Ital J Pediatr 2021 Jun 2;47(1):126. Epub 2021 Jun 2.

Endocrine Unit, Department of Medicine (DIMED), University of Padua, Padua, Italy.

Background: Autoimmune polyendocrinopathy-candidiasis-ectodermal-dystrophy (APECED) or autoimmune polyglandular syndrome Type 1 is a rare autosomal recessive syndrome. The disorder is caused by mutations in the AIRE (AutoImmune Regulator) gene. According to the classic criteria, clinical diagnosis requires the presence of at least two of three main components: chronic mucocutaneous candidiasis, hypoparathyroidism and primary adrenal insufficiency. Read More

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Atypical Brucella inopinata-Like Species in 2 Marine Toads.

Emerg Infect Dis 2021 06;27(6):1748-1750

We describe the isolation of atypical Brucella inopinata-like species and unique clinicopathologic findings in 2 adult marine toads (Rhinella marina), including oophoritis in 1 toad. These findings represent a novel emerging disease in toads and a possible zoonotic pathogen. Read More

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Wiad Lek 2021 ;74(3 cz 1):406-412


Objective: The aim: To obtain the first estimates of the current prevalence of healthcare-associated deep pelvic tissue infection and other infections of the female reproductive tract (vagina, ovaries, uterus) including chorioamnionitis, and antimicrobial resistance of causing pathogens in Ukraine.

Patients And Methods: Materials and methods: We performed a retrospective multicenter cohort study was based on surveillance data. The study population included 3,053 women's who underwent gynecological surgery or other procedures from 2017 to 2019 in 7 women hospitals in Ukraine. Read More

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Autoimmune Diseases in Patients with Premature Ovarian Insufficiency-Our Current State of Knowledge.

Int J Mol Sci 2021 Mar 5;22(5). Epub 2021 Mar 5.

Department of Gynecological Endocrinology, Poznan University of Medical Sciences, 60-535 Poznan, Poland.

Premature ovarian insufficiency (POI), previously known as premature ovarian failure or premature menopause, is defined as loss of ovarian function before the age of 40 years. The risk of POI before the age of 40 is 1%. Clinical symptoms develop as a result of estrogen deficiency and may include amenorrhea, oligomenorrhea, vasomotor instability (hot flushes, night sweats), sleep disturbances, vulvovaginal atrophy, altered urinary frequency, dyspareunia, low libido, and lack of energy. Read More

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Xanthogranulomatous Salpingo-Oophoritis Presenting as an Ovarian Malignancy.

Cureus 2021 Feb 15;13(2):e13363. Epub 2021 Feb 15.

Pathology, Maya Metro Hospital, Dhangadhi, NPL.

Xanthogranulomatous salpingo-oophoritis is an extremely rare entity. The clinical features are similar to the common benign and malignant adnexal diseases, making it difficult to diagnose. Here we present a case of pelvic mass with high level of tumor markers who was operated with suspicion of adnexal tumor. Read More

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February 2021

The Role of AIRE Deficiency in Infertility and Its Potential Pathogenesis.

Front Immunol 2021 19;12:641164. Epub 2021 Feb 19.

Department of Immunology, College of Basic Medical Sciences, Jilin University, Changchun, China.

The increasing number of patients with infertility is recognized as an emerging problem worldwide. However, little is known about the cause of infertility. At present, it is believed that infertility may be related to genetic or abnormal immune responses. Read More

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September 2021

Epidemiologic and Clinical Characteristics of Tubo-Ovarian Abscess, Hydrosalpinx, Pyosalpinx, and Oophoritis in Emergency Department Patients.

Cureus 2020 Nov 23;12(11):e11647. Epub 2020 Nov 23.

Emergency Medicine, Mayo Clinic, Jacksonville, USA.

Introduction Pelvic inflammatory disease (PID) is a spectrum of illness ranging from mild illness to more severe forms including tubo-ovarian abscess, hydrosalpinx, pyosalpinx, oophoritis (THPO). The objective of the study was to report rates and clinical characteristics of females presenting to the ED with a diagnosis of THPO in relationship to the presence or absence of sexually transmitted infections (STIs). Methods A database of ED patient encounters occurring from April 18, 2014, to March 7, 2017 was created. Read More

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November 2020

A form of secondary ovarian insufficiency (SOI) due to adrenal hypoandrogenism as new infertility diagnosis.

Endocrine 2021 04 2;72(1):260-267. Epub 2020 Oct 2.

The Center for Human Reproduction, New York, NY, 10021, USA.

Background: Mediated via the androgen receptor on granulosa cells, models of small growing follicle stages demonstrate dependence on testosterone. Androgen deficiency reduces ovarian response to follicle stimulation hormone (FSH), granulosa cell mass and estradiol (E2) production falls and FSH, therefore, rises. Though potentially of adrenal and/or ovarian origin, androgen deficiency in association with female infertility is almost universally primarily of adrenal origin, raising the possibility that women with presumptive diagnosis of primary ovarian insufficiency (POI), also called primary ovarian failure (POF) may actually suffer from secondary ovarian insufficiency (SOI) due to adrenal hypoandrogenism that leads to follicular arrest at small-growing follicle stages. Read More

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Mumps-Related Disease Burden in Japan: Analysis of JMDC Health Insurance Reimbursement Data for 2005-2017.

J Epidemiol 2021 Aug 13;31(8):464-470. Epub 2021 Jan 13.

Department of Pediatrics, Shizuoka Kosei Hospital.

Background: Mumps vaccination coverage is low in Japan, partly because of its voluntary nature. Although pediatric cases of mumps virus infection are captured by the National Epidemiological Surveillance of Infectious Diseases program under the Infectious Disease Law, there are currently no data regarding the occurrence of mumps and its complications in adults.

Methods: We investigated the annual incidence rates of mumps and its complications based on health insurance reimbursement data for 5,209,660 individuals aged 0-64 years for 2005-2017, obtained from JMDC Inc. Read More

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Hysterectomy and Oophorectomy in Reproductive Age: A Cross-Sectional Study from a Tertiary Care Hospital.

Cureus 2020 May 28;12(5):e8344. Epub 2020 May 28.

Pathology, Dow Medical College, Dow University of Health Sciences, Karachi, PAK.

Introduction Hysterectomy is a common surgical procedure in women, and oophorectomy may also be performed with the hysterectomy. The objective of this study was to identify clinical indications and pathological findings in hysterectomies, performed for gynecological causes, in women of reproductive age (15-49 years) and to determine if oophorectomy or ovarian conservation was performed with the hysterectomy as well as the pathological findings in the ovaries. Methods This cross-sectional study was conducted in the department of Pathology at Dow Medical College in Karachi, Pakistan, from September 2017 to December 2018. Read More

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Comparison and assessment of necropsy lesions in end-of-lay laying hens from different housing systems in Denmark.

Poult Sci 2020 Jan 30;99(1):119-128. Epub 2019 Dec 30.

Faculty of Health and Medical Science, Department of Veterinary and Animal Sciences, University of Copenhagen, DK-1870 Frederiksberg C, Denmark. Electronic address:

Apperantly healthy laying hens at the end of production (60 to 91 wk) were investigated for the occurrence of pathology and bacterial infections. In total, 7,477 hens from 15 flocks representing the following production systems: Enriched cages, barn housed layers, and organic/free range layers were necropsied. Indications of bacterial infection were investigated by bacteriological cultivation. Read More

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January 2020

Molecular and pathological investigation of a natural outbreak of Newcastle disease caused by genotype XVII in White Leghorn chickens.

Avian Pathol 2020 Aug 11;49(4):394-403. Epub 2020 Jun 11.

Central Diagnostic Laboratory, National Veterinary Research Institute, Vom, Nigeria.

Newcastle disease (ND) is an infectious viral poultry disease with great economic consequences. In developing countries, outbreaks of ND caused by virulent Newcastle disease virus (NDV) have been identified as a limiting factor to the growth of the poultry industry. Limited reports exist on the pathology of natural field infection caused by NDV genotype XVII in chickens. Read More

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Fitz-Hugh-Curtis Syndrome Presenting as Acute Abdomen.

Am J Med 2020 10 9;133(10):e596. Epub 2020 Apr 9.

Section of Digestive Disease, Yale School of Medicine, New Haven, Conn. Electronic address:

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October 2020

Toxicopathological, Cytogenetic Effects of Acetothioamide on Female Albino Mice Reproductive System.

Open Access Maced J Med Sci 2019 Dec 13;7(23):3925-3929. Epub 2019 Dec 13.

Department of Pathology, College of Veterinary Medicine, University of Diyala, Diyala, Iraq.

Aim: To determine toxicopathological and cytogenetic effects of Acetothioamide (ATA) on the female reproductive system.

Methods: Twenty albino female mice were divided equally into two groups: the first group (control) fed with diet pellet. The second group (treated) were inoculated intraperitoneally with a single dose of ATA (100 mg/kg Bw) for 15 days. Read More

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December 2019

Clinical and pathological features of women with adnexal masses admitted as emergency cases to the Gynaecology Department of West Kazakhstan University.

Prz Menopauzalny 2019 Dec 4;18(3):180-183. Epub 2019 Dec 4.

Department of Normal and Topographical Anatomy, West Kazakhstan Marat Ospanov Medical University, Aktobe, Kazakhstan.

Aim Of The Study: To detect the clinical and pathological features of women with adnexal masses (AMs) admitted as emergency cases to the Gynaecology Department of West Kazakhstan University.

Material And Methods: A retrospective analysis of the data of women with AMs admitted as an emergency cases to the Gynaecology Department of West Kazakhstan University. The collected data include: age, age of menarche and age of menopause, presenting symptoms, admission criteria - either self-referral or refereed from another department, ultrasound findings, associated pregnancy, associated pathology of the female genital tract, and post-operative histological results of surgically excised AMs (gold standard). Read More

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December 2019

Etiology, epidemiology, pathology, and advances in diagnosis, vaccine development, and treatment of infection in poultry: a review.

Vet Q 2020 Dec;40(1):16-34

Division of Pathology, ICAR - Indian Veterinary Research Institute, Bareilly, India.

is a Gram-negative bacterium of the family that resides normally in the respiratory and reproductive tracts in poultry. It is a major cause of oophoritis, salpingitis, and peritonitis, decreases egg production and mortality in hens thereby severely affecting animal welfare and overall productivity by poultry industries across Europe, Asia, America, and Africa. In addition, it has the ability to infect wider host range including domesticated and free-ranging avian hosts as well as mammalian hosts such as cattle, pigs and human. Read More

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December 2020

First Report of Isolation of from Layer Chickens in Morocco with Decrease in Laying Performance.

Avian Dis 2019 12;63(4):727-730

Clinic for Poultry and Fish Medicine, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine, Vienna 1210, Austria.

is a genus of the family of . It is well known as a commensal inhabitant of the respiratory and reproductive tract of healthy chickens. But in the last years, is increasingly reported in field cases with a decrease in laying performance due to infections of the reproductive tract. Read More

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December 2019

Pregnancy after mumps: a case report.

J Med Case Rep 2019 Dec 22;13(1):379. Epub 2019 Dec 22.

Department of Midwifery, Nursing and Midwifery Faculty, Tabriz University of Medical Sciences, Tabriz, Iran.

Introduction: Oophoritis, a complication of mumps, is said to affect only 5% of all postpubertal women. In this report, we present a case of a 31-year-old Iranian woman with amenorrhea and infertility due to an infantile uterus and atrophic ovaries associated with contracting mumps at a young age. She later successfully carried a healthy baby to term. Read More

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December 2019

Disruption of the Dimer-Dimer Interaction of the Mumps Virus Attachment Protein Head Domain, Aided by an Anion Located at the Interface, Compromises Membrane Fusion Triggering.

J Virol 2020 01 6;94(2). Epub 2020 Jan 6.

Department of Virology, Faculty of Medicine, Kyushu University, Fukuoka, Japan

Mumps virus (MuV), an enveloped negative-strand RNA virus belonging to the family , enters the host cell through membrane fusion mediated by two viral envelope proteins, an attachment protein hemagglutinin-neuraminidase (MuV-HN) and a fusion (F) protein. However, how the binding of MuV-HN to glycan receptors triggers membrane fusion is not well understood. The crystal structure of the MuV-HN head domain forms a tetramer (dimer of dimers) like other paramyxovirus attachment proteins. Read More

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January 2020