669 results match your criteria Oophoritis


Mumps outbreak investigation in Jaisalmer, Rajasthan, India, June-September 2016.

J Med Virol 2018 Sep 25. Epub 2018 Sep 25.

Department of Epidemiology, National Centre of Disease Control, Delhi, India.

Mumps, a vaccine-preventable disease, cause inflammation of salivary glands and may cause severe complications, such as encephalitis, meningitis, deafness, and orchitis/oophoritis. In India, mumps vaccine is not included in the universal immunization program and during 2009 to 2014, 72 outbreaks with greater than 1500 cases were reported. In August 2016, a suspected mumps outbreak was reported in Jaisalmer block, Rajasthan. Read More

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September 2018
1 Read

Fatal disseminated cytomegalovirus infection with necrotizing oophoritis in a patient with acquired immunodeficiency syndrome.

Autops Case Rep 2018 Jul-Sep;8(3):e2018029. Epub 2018 Jul 30.

Universidade de São Paulo, Faculty of Medicine, Department of Anatomic Pathology, Emergency Department and LIM06. São Paulo, SP, Brazil.

Disseminated human cytomegalovirus (CMV) disease occurs mainly as a congenital infection and among immunocompromised hosts. Patients with acquired immunodeficiency syndrome (AIDS) are at increased risk for CMV infection, and the most prevalent clinical manifestation is retinitis, followed by colitis, esophagitis, pneumonitis, and encephalitis. CMV oophoritis is poorly described in the literature with some cases reported in patients with hematological or solid malignancies, bone marrow or solid organ transplantation, immunosuppressive therapy, and advanced AIDS cases. Read More

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July 2018
9 Reads

Mumps: Resurgence of a once-dormant disease.

JAAPA 2018 May;31(5):19-22

Alanna M. Balbi is a medical student at the University of South Florida in Tampa, Fla. Amanda A. Van Sant practices in the ED at Lehigh Valley Health Network in Bethlehem, Pa. Eric W. Bean is an emergency medicine physician at Lehigh Valley Health Network. Jeanne L. Jacoby is assistant research director and an attending physician in the ED at Lehigh Valley Health Network and a clinical associate professor in the University of South Florida's Morsani College of Medicine. The authors have disclosed no potential conflicts of interest, financial or otherwise.

Mumps is a systemic viral illness, preventable by vaccination, that typically affects children and is characterized by unilateral or bilateral swelling of the parotid glands. Uncommon complications such as orchitis, oophoritis, deafness, pancreatitis, aseptic meningitis, and encephalitis occur more often in adults. Recent outbreaks of the disease appear to be caused by a failure to maintain herd immunity in certain populations, particularly in affluent white communities. Read More

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May 2018
2 Reads

Xanthogranulomatous Oophoritis Mimicking an Ovarian Neoplasm: A Rare Case Report.

J Midlife Health 2018 Jan-Mar;9(1):41-43

Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.

Xanthogranulomatous inflammation of female genital tract is uncommon and is usually seen in endometrium. Only a few cases involving the ovary have been reported. Its clinical manifestations, imaging modalities, and gross features can mimic ovarian malignancy. Read More

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Vaccination with outer membrane vesicles and the fimbrial protein FlfA offers improved protection against lesions following challenge with Gallibacterium anatis.

Vet Microbiol 2018 Apr 12;217:104-111. Epub 2018 Mar 12.

Department of Veterinary and Animals Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark. Electronic address:

Gallibacterium anatis is an opportunistic poultry pathogen belonging to the Pasteurellaceae family. It has been shown to cause oophoritis, salpingitis and peritonitis in hens, as well as being associated with reduced semen quality in cockerels. Widespread multidrug resistance and substantial antigenic variation among strains of Gallibacterium anatis is a major constraint to treatment with antimicrobials and prevention of infection by vaccination. Read More

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April 2018
6 Reads

Identification, differentiation and antibiotic susceptibility of isolates from diseased poultry.

Ir Vet J 2018;71. Epub 2018 Feb 5.

Friedrich-Loeffler-Institut (Federal Research Institute for Animal Health), Institute of Bacterial Infections and Zoonoses, Naumburger Str. 96a, 07743 Jena, Germany.

Background: is an opportunistic pathogen of intensively reared poultry causing oophoritis, salpingitis, peritonitis and enteritis. infection often remains undiagnosed. Recently multi-drug resistant isolates have been described. Read More

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February 2018
3 Reads

Bovine herpesvirus-1 in three major milk sheds of Ethiopia: Serostatus and association with reproductive disorders in dairy cattle.

Prev Vet Med 2018 Feb 1;150:126-132. Epub 2018 Jan 1.

School of Veterinary Medicine, Hawassa University, P.O. Box 05, Hawassa, Ethiopia. Electronic address:

Bovine herpesvirus-1 (BHV-1) causes infectious bovine rhinotracheitis (IBR), and infectious pustular vulvovaginitis (IPV) in cows and infectious pustular balanopostitis (IPB) in bulls worldwide. Infection of seronegative cattle with BHV-1 leads to abortion, retention of fetal membranes, increased service per conception, metritis and oophoritis. As part of an ongoing study on infectious causes of reproductive disorders in Ethiopia, this investigation aims at assessing the role of BHV-1 in the disorders and the risk factors affecting its seroprevalence. Read More

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February 2018
8 Reads

Primary Immunoprevention of Epithelial Ovarian Carcinoma by Vaccination against the Extracellular Domain of Anti-Müllerian Hormone Receptor II.

Cancer Prev Res (Phila) 2017 Nov;10(11):612-624

Department of Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio.

Epithelial ovarian carcinoma (EOC) is the most prevalent form of ovarian cancer in the United States, representing approximately 85% of all cases and causing more deaths than any other gynecologic malignancy. We propose that optimized control of EOC requires the incorporation of a vaccine capable of inducing safe and effective preemptive immunity in cancer-free women. In addition, we hypothesize that ovarian-specific self-proteins that are "retired" from autoimmune-inducing expression levels as ovaries age but are expressed at high levels in emerging EOC may serve as vaccine targets for mediating safe and effective primary immunoprevention. Read More

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November 2017
20 Reads

An incidental finding of chronic salpingitis complications: Tubo-uterine fistula.

J Exp Ther Oncol 2017 Sep;11(2):81-83

Zekai Tahir Burak Women's Health Research and Education Hospital, Department of Obstetrics and Gynecology; Division of Gynecological Endocrinology, Ankara, Turkey.

Objective: Pelvic inflammatory disease (PID) is an infection of the upper genital tract in women that can include endometritis, parametritis, salpingitis, oophoritis, tubo-ovarian abscess, and peritonitis. The spectrum of the disease ranges from subclinical and asymptomatic infection to severe, lifethreatening illness; squealae include chronic pelvic pain, ectopic pregnancy, and infertility. In this case we report an uncommon complication of pelvic inflammatory disease, a tubo-uterian fistula. Read More

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September 2017
22 Reads

MR Imaging of Xanthogranulomatous Oophoritis.

Magn Reson Med Sci 2018 07 29;17(3):191-192. Epub 2017 Sep 29.

Department of Radiology, Shimane University Faculty of Medicine.

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July 2018
4 Reads

Tubo-ovarian abscess infected by .

BMJ Case Rep 2017 Aug 20;2017. Epub 2017 Aug 20.

Oxford University Clinical Research Unit, Patan Hospital, Kathmandu, Nepal.

We report a case of a tubo-ovarian abscess infected with serotype A 19-year-old Nepalese woman presented to a hospital in Kathmandu with lower abdominal pain, constipation, fever and a non-healing, suppurative surgical wound from an emergency caesarian section performed 2 months previously at 37 weeks of pregnancy. She also had an exploratory laparotomy for an appendix perforation with peritonitis at 25 weeks of gestation. Her wound infection did not respond to cloxacillin and she had an exploratory laparotomy, and a tubo-ovarian abscess was found from which was isolated. Read More

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August 2017
27 Reads

[THE FREQUENCY OF FACTORS CONTRIBUTING TO THE FORMATION OF ADHESIONS IN THE ABDOMINAL CAVITY IN WOMEN].

Authors:
F Akhmedov

Georgian Med News 2017 Jul-Aug(268-269):94-98

Azerbaijan Institute of Experimental Surgery named after M. Topchubashev, Baku.

To determine the major factor that contributed to the formation of adhesions in the abdominal cavity in women with a history of surgical interventions, examined 86 women with adhesive disease (main group) in the past have suffered various surgeries. The average age of patients was 35,7±5,6 years. Clinical examination of patients included a collection of complaints, anamnesis of disease and life, physical examination. Read More

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December 2017
5 Reads

Pelvic inflammatory disease: diagnosis and treatment in the emergency department [digest].

Emerg Med Pract 2016 Dec 22;18(12 Suppl Points & Pearls):S1-S2. Epub 2016 Dec 22.

Department of Emergency Medicine, Icahn School of Medicine at Mount Sinai, New York, NY.

Pelvic inflammatory disease is a common disease that is associated with significant complications including infertility, chronic pelvic pain, ruptured tubo-ovarian abscess, and ectopic pregnancy. The diagnosis may be delayed when the presentation has nonspecific signs and symptoms. Even when it is properly identified, pelvic inflammatory disease is often treated suboptimally. Read More

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December 2016

Case Of Xanthogranulomatous Oophoritis.

J Ayub Med Coll Abbottabad 2017 Jan-Mar;29(1):162-164

Department of Histopathology, Aga Khan University Hospital, Karachi, Pakistan.

Xanthogranulomatous inflammation is characterized by destruction of the tissues of the organ involved and replacement by chronic inflammatory cells such as lymphocytes, plasma cells, occasional neutrophils with or without multinucleated or Touton giant cells. Exact aetiology is not known but the theory of infection with organisms like Proteus, E coli, and Bacteroides fragilis is most popular. Xanthogranulomatous inflammation of the female genital tract is not common and usually involves the endometrium; however, xanthogranulomatous inflammation of the ovaries is a rare entity. Read More

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July 2017
8 Reads

Identification of patients with primary ovarian insufficiency caused by autoimmunity.

Reprod Biomed Online 2017 Oct 21;35(4):475-479. Epub 2017 Jun 21.

Center for Reproductive Medicine, Shandong University, Jinan, 250001, Shandong, China; National Research Center for Assisted Reproductive Technology and Reproductive Genetics, Jinan, 250001, Shandong, China; The Key laboratory of Reproductive Endocrinology (Shandong University), Ministry of Education, Jinan, 250001, Shandong, China; Center for Reproductive Medicine, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, 200135, China; Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Shanghai, 200135, China.

Autoimmune pathogenesis is responsible for a subset of primary ovarian insufficiency (POI) cases. The significance of autoantibodies for POI, however, remains unclear. A total of 250 women with idiopathic POI and 256 age-matched healthy women were enrolled. Read More

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October 2017
5 Reads

Abdominal and pelvic actinomycosis due to longstanding intrauterine device: a slow and devastating infection.

Autops Case Rep 2017 Jan-Mar;7(1):43-47. Epub 2017 Mar 30.

Division of Surgery - Hospital Universitário - Universidade de São Paulo, São Paulo/SP - Brazil.

Actinomycosis is a chronic or subacute bacterial infection characterized by large abscess formation, caused mainly by the gram-positive non-acid-fast, anaerobic, or microaerophilic/capnophilic, obligate parasites bacteria from the genus. Although pelvic inflammatory disease is an entity associated with the longstanding use of intrauterine devices (IUDs), actinomycosis is not one of the most frequent infections associated with IUDs. We present the case of a 43-year-old female patient who was referred to the emergency facility because of a 20-day history of abdominal pain with signs of peritoneal irritation. Read More

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March 2017
21 Reads

Enterobius vermicularis in tubo-ovarian abscess: A rare and interesting incidental finding - A case Report.

J Pak Med Assoc 2017 Apr;67(4):630-633

Department of Pathology and Laboratory Medicine, The Aga Khan University Hospital, Karachi.

Enterobius vermicularis is a common intestinal nematode; however, rare extraintestinal Enterobius infections have been reported from different parts of the world. Here, we present a case of tubo-ovarian abscess in an otherwise healthy young sexually active female with no known comorbids with history of on and off lower abdominal pain for one year and high grade fever for one month. On the basis of further workup and radiological evaluation, a preoperative diagnosis of right sided tubo-ovarian abscess was made and salpingo-oophorectomy was performed laproscopically in July 2015. Read More

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April 2017
8 Reads

Assessment of health and welfare of Austrian laying hens at slaughter demonstrates influence of husbandry system and season.

Br Poult Sci 2017 Jun 15;58(3):209-215. Epub 2017 Mar 15.

a Clinic for Poultry and Fish Medicine, Department for Farm Animals and Veterinary Public Health , University of Veterinary Medicine , Vienna , Austria.

1. Selected health and welfare variables of laying hens from 79 flocks kept in alternative husbandry systems were assessed at the end of lay. 2. Read More

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June 2017
1 Read

MRI in pelvic inflammatory disease: a pictorial review.

Abdom Radiol (NY) 2017 03;42(3):935-950

Department of Medical Imaging, University of Arizona, 1501 N Campbell Ave., PO Box 245067, Tucson, AZ, 85724, USA.

Pelvic inflammatory disease (PID) is an ascending infection of the female genital tract caused by the spread of bacteria from the vagina to the pelvic reproductive organs and occasionally the peritoneum. The most common causative organisms are sexually transmitted. PID is a significant source of morbidity among reproductive age women both as a cause of abdominal pain and as a common cause of infertility. Read More

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March 2017
9 Reads

Bidirectional Estrogen-Like Effects of Genistein on Murine Experimental Autoimmune Ovarian Disease.

Int J Mol Sci 2016 Nov 8;17(11). Epub 2016 Nov 8.

State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, China.

This study was to investigate the bidirectional estrogen-like effects of genistein on murine experimental autoimmune ovarian disease (AOD). Female BALB/c mice were induced by immunization with a peptide from murine zona pellucida. The changes of estrous cycle, ovarian histomorphology were measured, and the levels of serum sex hormone were analyzed using radioimmunoassay. Read More

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November 2016
22 Reads

Ovarian dysfunction associated with zona pellucida-based immunocontraceptive vaccines.

Theriogenology 2017 Feb 17;89:329-337. Epub 2016 Sep 17.

Section of Reproduction, Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, South Africa.

Despite more than 40 years of research into zona pellucida (ZP)-based vaccines, relatively little is known about their mechanism of action. Early research demonstrated precipitation of ZP glycoproteins by antiovarian antiserum, rendering oocytes resistant to sperm binding in vitro. Subsequent work showed significantly decreased fertilization rates following passive immunization, sparking interest in anti-ZP immunocontraception for human and animal use. Read More

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February 2017
26 Reads

Pelvic Inflammatory Disease: Multimodality Imaging Approach with Clinical-Pathologic Correlation.

Radiographics 2016 Sep-Oct;36(5):1579-96

From the Department of Diagnostic Radiology (M.V.R., M.M., H.B.D., M.S.) and Department of Obstetrics and Gynecology and Reproductive Sciences (M.L.M.), Yale University School of Medicine, 333 Cedar St, PO Box 208042, Room TE-2, New Haven, CT 06520.

Pelvic inflammatory disease (PID) is a common medical problem, with almost 1 million cases diagnosed annually. Historically, PID has been a clinical diagnosis supplemented with the findings from ultrasonography (US) or magnetic resonance (MR) imaging. However, the diagnosis of PID can be challenging because the clinical manifestations may mimic those of other pelvic and abdominal processes. Read More

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September 2017
69 Reads

Releasing the genomic RNA sequestered in the mumps virus nucleocapsid.

J Virol 2016 Aug 31. Epub 2016 Aug 31.

Department of Chemistry, Institute of Biomedical Sciences, Georgia State University, Atlanta, Georgia, USA, 30302

In a negative strand RNA virus, the genomic RNA is sequestered inside the nucleocapsid when the viral RNA-dependent RNA polymerase uses it as the template for viral RNA synthesis. It must require a conformational change in the nucleocapsid protein (NP) to make the RNA accessible by the viral polymerase during this process. The structure of an empty mumps virus nucleocapsid-like particle is determined to 10. Read More

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August 2016
13 Reads

Estimating true hospital morbidity of complications associated with mumps outbreak, England, 2004/05.

Authors:
C F Yung M Ramsay

Euro Surveill 2016 Aug;21(33)

Infectious Disease Service, Department of Paediatrics, KK Women's and Children's Hospital, Singapore.

Mumps outbreaks in highly vaccinated populations continue to be reported globally. Therefore, quantifying the burden of mumps morbidity accurately will be necessary to better assess the impact of mumps vaccination programmes. We aim to estimate the true morbidity resulting from mumps complications in terms of hospitalised orchitis, meningitis, oophoritis and pancreatitis in England during the outbreak in 2004/05. Read More

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August 2016
3 Reads

Histopathologic findings in uteri and ovaries collected from clinically healthy dogs at elective ovariohysterectomy: a cross-sectional study.

J Vet Sci 2017 Sep;18(3):407-414

Research Group on Veterinary Sciences Centauro School of Veterinary Medicine, Faculty of Agrarian Sciences, University of Antioquia, Medellin 050010, Colombia.

Opinions on ovariohysterectomy (OHE) of bitches vary depending on region and country. In this descriptive, prospective cross-sectional study, uterine tracts and ovaries exhibiting gross pathologic findings (n = 76) were collected post-surgery from a reference population of 3,600 bitches (2.11% incidence) that underwent elective OHE during September to November 2013 and evaluated by histopathology examination. Read More

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September 2017
6 Reads

Mumps virus induces innate immune responses in mouse ovarian granulosa cells through the activation of Toll-like receptor 2 and retinoic acid-inducible gene I.

Mol Cell Endocrinol 2016 11 28;436:183-94. Epub 2016 Jul 28.

School of Basic Medicine, Peking Union Medical College, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, China. Electronic address:

Mumps virus (MuV) infection may lead to oophoritis and perturb ovarian function. However, the mechanisms underlying the activation of innate immune responses to MuV infection in the ovary have not been investigated. This study showed that Toll-like receptor 2 (TLR2) and retinoic acid-inducible gene I (RIG-I) cooperatively initiate innate immune responses to MuV infection in mouse ovarian granulosa cells. Read More

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November 2016
8 Reads

"Filarial dance sign" real-time ultrasound diagnosis of filarial oophoritis.

J Clin Ultrasound 2016 Oct 30;44(8):500-1. Epub 2016 Apr 30.

Abhishek's Institute of Imageology, Hyderabad, Telangana State, India.

Filariasis is a parasitic disease caused by Filarial nematodes (Wuchereria bancrofti, Brugia malayi, and Brugia timori) that commonly causes lymphatic obstruction resulting in edema and increase in the size of the affected organ. Filariasis is diagnosed by identifying microfilariae on Giemsa stain. The immunochromatographic card test is diagnostic. Read More

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October 2016
5 Reads

Tubo-Ovarian Abscess (with/without Pseudotumor Area) Mimicking Ovarian Malignancy: Role of Diffusion-Weighted MR Imaging with Apparent Diffusion Coefficient Values.

PLoS One 2016 19;11(2):e0149318. Epub 2016 Feb 19.

Department of Radiology, Xinhua Hospital affiliated to Shanghai Jiao Tong University School of Medicine, 1665 Kong Jiang Road, Shanghai 200092, China.

Objective: To assess the added value of diffusion-weighted magnetic resonance imaging (DWI) with apparent diffusion coefficient (ADC) values compared to MRI, for characterizing the tubo-ovarian abscesses (TOA) mimicking ovarian malignancy.

Materials And Methods: Patients with TOA (or ovarian abscess alone; n = 34) or ovarian malignancy (n = 35) who underwent DWI and MRI were retrospectively reviewed. The signal intensity of cystic and solid component of TOAs and ovarian malignant tumors on DWI and the corresponding ADC values were evaluated, as well as clinical characteristics, morphological features, MRI findings were comparatively analyzed. Read More

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August 2016
15 Reads

Age peculiarities of reproductive morbidity in female participants of the ChNPP accident consequences clean up (according to the figures from SRU, 1988-2012 survey period).

Probl Radiac Med Radiobiol 2015 Dec;20:366-75

State Institution National Research Center for Radiation Medicine of National Academy of MedicalSciences of Ukraine, Melnikova str., 53, Kyiv, 04050, Ukraine.

Objective: to assess and estimate the peculiarities of genital system morbidity in female participants of the ChNPP accident clean up works in 1986-1987 depending on age at exposure to ionizing radiation and time since exposure.

Materials And Methods: Data on the Chernobyl disaster survivors received from the State Registry of Ukraine are out line in the paper. Review of the level and pattern of genital system morbidity was carried out for the 17,237 female participants of the ChNPP accident clean up works in 1986-1987 depending on time under risk upon radiation expo sure and reproductive age at exposure. Read More

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December 2015
4 Reads

Regulation of Murine Ovarian Epithelial Carcinoma by Vaccination against the Cytoplasmic Domain of Anti-Müllerian Hormone Receptor II.

J Immunol Res 2015 5;2015:630287. Epub 2015 Nov 5.

Department of Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA ; Department of Biology, Cleveland State University, Cleveland, OH, USA ; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA.

Anti-Müllerian hormone receptor, type II (AMHR2), is a differentiation protein expressed in 90% of primary epithelial ovarian carcinomas (EOCs), the most deadly gynecologic malignancy. We propose that AMHR2 may serve as a useful target for vaccination against EOC. To this end, we generated the recombinant 399-amino acid cytoplasmic domain of mouse AMHR2 (AMHR2-CD) and tested its efficacy as a vaccine target in inhibiting growth of the ID8 transplantable EOC cell line in C57BL/6 mice and in preventing growth of autochthonous EOCs that occur spontaneously in transgenic mice. Read More

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September 2016
17 Reads

Mumps Outbreak among Highly Vaccinated Teenagers and Children in the Central Region of Portugal, 2012-2013.

Acta Med Port 2015 Jul-Aug;28(4):435-41. Epub 2015 Aug 31.

Departamento de Saúde Pública. Administração Regional de Saúde do Centro. Coimbra. Portugal.

Introduction: Mumps vaccine was introduced in the National Immunization Program in Portugal in 1987, rapidly reaching a national coverage > 92%, with important reduction in the annual incidence of the disease. We report a mumps outbreak in the Central Region of Portugal, occurred in the winter 2012-13.

Material And Methods: Cases of salivary-gland swelling and other symptoms compatible with mumps were investigated. Read More

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February 2018
8 Reads

The role of autoimmunity in premature ovarian failure.

Iran J Reprod Med 2015 Aug;13(8):461-72

Department of Obstetrics and Gynecology, Moheb-e-Yas Women General Hospital, Faculty of Medicine, Tehran University of Medical Sciences and Health Services, Tehran, Iran .

Premature ovarian failure (POF) is a heterogeneous syndrome with several causative factors. Autoimmune mechanisms are involved in pathogenesis of 4-30 % of POF cases. The present review focuses on the role of autoimmunity in the pathophysiology of POF. Read More

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August 2015
23 Reads

Does the Degree of Perihepatitis Have Any Relevance to the Severity of the Manifestations of Pelvic Inflammatory Disease on Multidetector Computed Tomography?

J Comput Assist Tomogr 2015 Nov-Dec;39(6):901-6

From the Department of Radiology, Kyung Hee University Hospital at Gangdong, School of Medicine, Kyung Hee University, Seoul, Republic of Korea.

Purpose: This study aimed to evaluate the relationship between the degree of perihepatitis and the severity of pelvic inflammatory disease (PID) on multidetector computed tomography (MDCT).

Methods: A total of 177 women with PID who underwent biphasic abdominal computed tomography (CT) scans were enrolled. Two reviewers retrospectively reviewed the CT scans with consensus and subjectively categorized the severity of PID into 4 grades (normal, mild, moderate, and severe). Read More

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February 2016
14 Reads

Xanthogranulomatous Oophoritis Presenting as an Adnexal Mass and Bowel Obstruction. A Case Report.

J Reprod Med 2015 May-Jun;60(5-6):273-6

Background: Xanthogranulomatous inflammation of the female genital tract is a rare entity. When the gynecological organs are affected, it is particularly unusual for xanthogranulomataus inflammation to involve only the ovary.

Case: A 45-year-old woman with an intrauterine device, long-term exposure to nicotine, and hyperlipidemia presented with an adnexal mass and bowel obstruction. Read More

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July 2015
1 Read

Xanthogranulomatous oophoritis mimicking malignancy: a diagnostic dilemma.

BMJ Case Rep 2015 Jun 25;2015. Epub 2015 Jun 25.

Department of Obstetrics and Gynaecology, Hamdard Institute of Medical Sciences and Research, New Delhi, India.

Xanthogranulomatous inflammation is a chronic condition in which the affected organ is replaced by lipid-filled macrophages with plasma cells, lymphocytes and neutrophils. It is very rare in the ovaries. A case of xanthogranulomatous oophoritis in a premenopausal multiparous woman presenting with abnormal uterine bleeding and adnexal mass whose clinical and imaging findings suggested malignancy is reported. Read More

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June 2015
3 Reads

Chrono- and Immunocorrection of Inflammatory Disorders of Internal Reproductive Organs in Women of Reproductive Age.

Bull Exp Biol Med 2015 May 3;159(1):62-5. Epub 2015 Jun 3.

Research Institute of Physiology and Fundamental Medicine, Novosibirsk, Russia,

We compared the effectiveness of immunomodulators used in the treatment of patients with chronic salpingitis and oophoritis with or without changes in succinate dehydrogenase (SDH) activity in blood lymphocytes at incubation with the drug. Diurnal variations in individual reaction of SDH in blood lymphocytes to thymalin or ridostin were revealed. In the groups of women receiving ridostin or thymalin during the reaction of lymphocyte SDH to it, improvement of clinical laboratory and immunological parameters was observed in the majority of the patients and no effect was found in a lesser group of patients than in the groups treated with drugs during the absence of lymphocyte SDH reaction thereto. Read More

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May 2015
3 Reads

Pseudoactinomycotic Radiate Granules (PAMRAGs)- An Unusual Differential Diagnosis for Ovarian Neoplasm; A Diagnostic Dilemma.

J Clin Diagn Res 2015 Mar 1;9(3):ED01-2. Epub 2015 Mar 1.

Professor and Head of the Department, Department of Pathology, Governtment, Medical College , Kottayam, Kerala, India .

Pseudoactinomycotic radiate granules (PAMRAGs) are rarely detected lesions in ovary. Endometrium is the usual site and a detailed search of literature yielded only two cases in the ovary. PAMRAGs must be differentiated from actinomycotic granules which are also strongly associated with the use of intrauterine contraceptive devices (IUCDs). Read More

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March 2015
16 Reads

Autoimmune oophoritis: a rarely encountered ovarian lesion.

Indian J Pathol Microbiol 2015 Apr-Jun;58(2):249-51

Department of Pathology, Bahrain Specialist Hospital, Juffair, Manama, Bahrain.

Autoimmune oophoritis is a rare disorder causing ovarian failure clinically characterized by amenorrhea and infertility. It often occurs in a setting of autoimmune polyendocrine syndromes. A 38-year-old female presented with a 3 years history of secondary amenorrhea. Read More

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April 2016
3 Reads

Ovarian function and reproductive outcomes of female patients with systemic lupus erythematosus and the strategies to preserve their fertility.

Obstet Gynecol Surv 2015 Mar;70(3):196-210

Professor, Obstetrics and Gynecology, Department of Obstetrics and Gynecology, Division Reproductive Endocrinology and Infertility, School of Medicine, Koc University, Istanbul, Turkey.

Systemic lupus erythematosus (SLE) is a chronic autoimmune systemic disease that mainly affects women of reproductive age. Emerging data from recent molecular studies show us that estrogen hormone plays a central role in the development of this disease. By acting via its cognate receptors ERα and ERβ expressed on immune cells, estrogen can modulate immune function in both the innate and adaptive immune responses. Read More

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March 2015
7 Reads

Autoantibody response against NALP5/MATER in primary ovarian insufficiency and in autoimmune Addison's disease.

J Clin Endocrinol Metab 2015 May 3;100(5):1941-8. Epub 2015 Mar 3.

Department of Internal Medicine (A.B., S.M., V.M., A.F.), University of Perugia, 06126 Perugia, Italy; Department of Medical Sciences (M.A., O.K.), Science for Life Laboratory, Uppsala University, 750 03 Uppsala, Sweden; Centre of Molecular Medicine (M.A., A.H., O.K.), Department of Medicine (Solna), Karolinska Institutet, 171 76 Stockholm, Sweden; Division of Endocrinology, Diabetology, and Metabolism (R.G.), Department of Medical Sciences, University of Turin, 10126 Turin, Italy; Department of Cardio-Thoracic and Respiratory Science (A.D.B.), Endocrinology Unit, Second University of Naples, 80132 Naples, Italy; and Department of Pediatrics-Neonatal Intensive Care (R.P.), V. Fazzi Regional Hospital, 73100 Lecce, Italy.

Context: NACHT leucine-rich-repeat protein 5 (NALP5)/maternal antigen that embryo requires (MATER) is an autoantigen in hypoparathyroidism associated with autoimmune polyendocrine syndrome type 1 (APS1) but is also expressed in the ovary. Mater is an autoantigen in experimental autoimmune oophoritis.

Objectives: The objectives of the study were to determine the frequency of NALP5/MATER autoantibodies (NALP5/MATER-Ab) in women with premature ovarian insufficiency (POI) and in patients with autoimmune Addison's disease (AAD) and to evaluate whether inhibin chains are a target for autoantibodies in POI. Read More

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May 2015
5 Reads

Controlled reperfusion for different durations in the treatment of ischemia-reperfusion injury of the rat ovary: evaluation of biochemical features, molecular gene expression, and histopathology.

Can J Physiol Pharmacol 2015 Apr 16;93(4):269-74. Epub 2015 Jan 16.

Department of Obstetrics and Gynecology, Faculty of Medicine, Ataturk University, Erzurum 25250, Turkey.

High numbers of proinflammatory cells (PMNLs), which are carried by the blood to ischemic tissue during reperfusion, are considered responsible for inducing the inflammatory response that occurs in ischemia-reperfusion (I/R) injury. Our objective was to determine the controlled reperfusion (CR) interval duration (CRID) that would minimize the injury caused by the PMNLs that infiltrate ischemic tissue. Animal groups were divided into the following groups: Sham group, ovarian I/R group (OIR), and ovarian ischemia controlled-reperfusion groups OICR-1, OICR-2, OICR-3, OICR-4, OICR-5, OICR-6, which had their ovarian artery opened and then closed for 10, 8, 6, 4, 2, or 1 s, respectively. Read More

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April 2015
7 Reads

Preoperative Neutrophil-to-Lymphocyte Ratio Has a Better Predictive Capacity in Diagnosing Tubo-Ovarian Abscess.

Gynecol Obstet Invest 2015 14;80(4):234-9. Epub 2015 Feb 14.

Department of Obstetrics and Gynecology at Ataturk Training and Research Hospital, Ankara, Turkey.

Background: The aim of this study is to identify the inflammatory markers which predict a tubo-ovarian abscess (TOA) in the most accurate way.

Methods: This study involves 312 women. Preoperative inflammatory markers in the study group were compared with those in the healthy control group to identify the most efficient predictor of TOA with a high sensitivity and specificity. Read More

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September 2016
6 Reads

Immunocontraceptives: How far from reality?

Adv Biomed Res 2014 6;3:247. Epub 2014 Dec 6.

Department of Pathology, Pt. B. D. Sharma PGIMS, Rohtak, Haryana, India.

Despite high expectations of safer, effective, economical, longer acting contraceptives, to date, there are no licensed contraceptive vaccines available in the market. Nevertheless, a role for vaccines undoubtedly exists as an aid to birth spacing and as a nonsurgical means of generating sterility. The research concerned in the area so far has been successful on the feline population, with room still for exhaustive studies on humans. Read More

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January 2015
2 Reads

Metabolic endotoxaemia--a potential novel link between ovarian inflammation and impaired progesterone production.

Gynecol Endocrinol 2015 Apr 24;31(4):309-12. Epub 2014 Dec 24.

Repromed, Dulwich , South Australia , and.

Introduction: Medical conditions such as obesity and inflammatory bowel disease are associated with impaired luteal function, menstrual disturbance and infertility. It is proposed that the disturbance in gut wall integrity ("leaky gut") seen in these conditions may result in the passage of bacterial endotoxin (LPS) from the colonic lumen into the circulation that may initiate inflammation in the ovary and subsequently impair hormone production.

Methods: Quantify the association between systemic levels of LBP, a marker of endotoxin exposure, and levels of inflammation in the ovary (follicular fluid IL-6), plus steroid hormone production in 45 women undergoing IVF treatment. Read More

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April 2015
10 Reads

Ovarian autoimmune disease: clinical concepts and animal models.

Cell Mol Immunol 2014 Nov 20;11(6):510-21. Epub 2014 Oct 20.

Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS, USA.

The ovary is not an immunologically privileged organ, but a breakdown in tolerogenic mechanisms for ovary-specific antigens has disastrous consequences on fertility in women, and this is replicated in murine models of autoimmune disease. Isolated ovarian autoimmune disease is rare in women, likely due to the severity of the disease and the inability to transmit genetic information conferring the ovarian disease across generations. Nonetheless, autoimmune oophoritis is often observed in association with other autoimmune diseases, particularly autoimmune adrenal disease, and takes a toll on both society and individual health. Read More

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November 2014
7 Reads

A case report of a 19-week gravid patient with a dehisced abdominal wound and treated with V.A.C. ATS(®) Therapy System.

Int Wound J 2016 Oct 11;13(5):992-5. Epub 2014 Sep 11.

Department of General Surgery, Hyogo Prefectural Nishinomiya Hospital, Hyogo, Japan.

Negative pressure wound therapy (NPWT) is an effective treatment for various non-healing wounds, and V.A.C. Read More

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October 2016
6 Reads

The effect of the antioxidant drug "U-74389G" on oophoritis during ischemia reperfusion injury in rats.

Antiinflamm Antiallergy Agents Med Chem 2014 ;13(2):103-7

Department of Obstetrics & Gynecology, Mesologi County Hospital, Etoloakarnania, Greece.

Unlabelled: The aim of this experiment was to study the effects of the antioxidant drug "U-74389G" on rat model, particularly in ischemia reperfusion protocol. The beneficial or other effects of that molecule were studied estimating the mean oophoritis (OI) lesions.

Materials And Methods: 40 rats were used of mean weight 231. Read More

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June 2015
5 Reads

Invited review: Systematic review of diagnostic tests for reproductive-tract infection and inflammation in dairy cows.

J Dairy Sci 2014 Jul 16;97(7):3983-99. Epub 2014 May 16.

Cognosco, Anexa Animal Health, Morrinsville 3300, New Zealand.

The objective of this study was to conduct a systematic and critical appraisal of the quality of previous publications and describe diagnostic methods, diagnostic criteria and definitions, repeatability, and agreement among methods for diagnosis of vaginitis, cervicitis, endometritis, salpingitis, and oophoritis in dairy cows. Publications (n=1,600) that included the words "dairy," "cows," and at least one disease of interest were located with online search engines. In total, 51 papers were selected for comprehensive review by pairs of the authors. Read More

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July 2014
3 Reads

CT findings of acute pelvic inflammatory disease.

Abdom Imaging 2014 Dec;39(6):1350-5

Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Purpose: To determine the computed tomographic (CT) findings of acute pelvic inflammatory disease (PID).

Methods: This retrospective, single-institution case-control study was approved by our institutional review board, and the informed consent was waived owing to the retrospective nature of the study. CT images of 32 women with clinically proven acute PID and 32 control subjects with other conditions of similar presentation were retrospectively reviewed. Read More

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December 2014
6 Reads

A rare case of xanthogranulomatous oopharitis.

J Cancer Res Ther 2014 Jan-Mar;10(1):209-10

Department of Pathology, Cancer Institute (WIA), Adyar, Chennai, Tamil Nadu, India.

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December 2014
3 Reads