319 results match your criteria Oncologic Emergencies


The Tale of a Rubbery White Clot: Poorly Differentiated Spindle Cell Sarcoma Presenting As Superior Vena Cava Syndrome.

Cureus 2022 May 17;14(5):e25071. Epub 2022 May 17.

Department of Oncology, St Luke's Hospital, Bethlehem, USA.

Sarcoma is an uncommon neoplasm of mesenchymal origin (1). The presentation is usually vague. It may present as a mass in the thigh or retroperitoneum, with resultant pain or paresthesia of the affected area. Read More

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Characterization of older adults with cancer seeking acute emergency department care: A prospective observational study.

J Geriatr Oncol 2022 Jun 16. Epub 2022 Jun 16.

Departments of Emergency Medicine and Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH, USA. Electronic address:

Introduction: Disparities in care of older adults in cancer treatment trials and emergency department (ED) use exist. This report provides a baseline description of older adults ≥65 years old who present to the ED with active cancer.

Materials And Methods: Planned secondary analysis of the Comprehensive Oncologic Emergencies Research Network observational ED cohort study sponsored by the National Cancer Institute. Read More

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Oncologic emergencies and urgencies: A comprehensive review.

CA Cancer J Clin 2022 Jun 2. Epub 2022 Jun 2.

Department of Emergency Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Patients with advanced cancer generate 4 million visits annually to emergency departments (EDs) and other dedicated, high-acuity oncology urgent care centers. Because of both the increasing complexity of systemic treatments overall and the higher rates of active therapy in the geriatric population, many patients experiencing acute decompensations are frail and acutely ill. This article comprehensively reviews the spectrum of oncologic emergencies and urgencies typically encountered in acute care settings. Read More

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Burden, risk factors, and management of neutropenic fever among solid cancer patients in Ethiopia.

SAGE Open Med 2022 19;10:20503121221098236. Epub 2022 May 19.

Clinical Pharmacy Unit, Department of Pharmacy, College of Health Sciences, Debre Markos University, Debre Markos, Ethiopia.

Objectives: Although neutropenic fever is one of the most well-known oncologic emergencies and the common causes of death, a few studies have been conducted in resource-limited countries, particularly in Ethiopia. This study aimed to assess the burden, risk factors, and management of neutropenic fever among solid cancer patients in Ethiopia.

Methods: A hospital-based retrospective follow-up study was conducted from January 2017 to February 2021. Read More

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Palliative Care Needs and Clinical Outcomes of Patients with Advanced Cancer in the Emergency Department.

J Palliat Med 2022 May 13. Epub 2022 May 13.

Department of Emergency Medicine and Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.

Older adults with cancer use the emergency department (ED) for acute concerns. Characterize the palliative care needs and clinical outcomes of advanced cancer patients in the ED. A planned secondary data analysis of the Comprehensive Oncologic Emergencies Research Network (CONCERN) data. Read More

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Management decisions of an Academic Radiology Department during COVID-19 pandemic: the important support of a business analytics software.

Eur Radiol 2022 Apr 5. Epub 2022 Apr 5.

Department of Medical Surgical Sciences and Translational Medicine, Sapienza University of Rome - Sant'Andrea University Hospital, Via di Grottarossa, 1035-1039, 00189, Rome, Italy.

Objectives: To analyze the response in the management of both radiological emergencies and continuity of care in oncologic/fragile patients of a radiology department of Sant'Andrea Academic Hospital in Rome supported by a dedicated business analytics software during the COVID-19 pandemic.

Methods: Imaging volumes and workflows for 2019 and 2020 were analyzed. Information was collected from the hospital data warehouse and evaluated using a business analytics software, aggregated both per week and per quarter, stratified by patient service location (emergency department, inpatients, outpatients) and imaging modality. Read More

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Hyperleukocytosis and leukostasis in acute and chronic leukemias.

Leuk Lymphoma 2022 Mar 31:1-12. Epub 2022 Mar 31.

Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Leukostasis is a life-threatening complication of high concentrations of circulating leukemic cells, most often myeloblasts. Effective care of patients with leukostasis involves early recognition and treatment, and aggressive management of concurrent complications of the underlying leukemia. The relatively poor prognosis in patients with leukostasis underscores the importance of the timely and effective care of this hematologic emergency. Read More

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Neuro-oncologic Emergencies.

Curr Oncol Rep 2022 Mar 30. Epub 2022 Mar 30.

Department of Neurology and Neurosurgery, Mayo Clinic, Jacksonville, FL, USA.

Purpose Of Review: Patients with brain and spine tumors are at high risk of presenting cancer-related complications at disease presentation or during active treatment and are usually related to the type and location of the lesion. Here, we discuss presentation and management of the most common emergencies affecting patients with central nervous system neoplastic lesions.

Recent Findings: Tumor-related emergencies encompass complications in patients with central nervous system neoplasms, as well as neurologic complications in patients with systemic malignancies. Read More

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Ostomy closure rate during COVID-19 pandemic: an Italian multicentre observational study.

Updates Surg 2022 Jun 24;74(3):1017-1025. Epub 2022 Mar 24.

Vita-Salute San Raffaele University, Via Olgettina, 58, 20132, Milan, Italy.

During the corona virus disease 2019 (COVID-19) pandemic, most of the surgical procedures were performed for emergencies or oncologic reasons to the detriment of the remaining elective procedures for benign conditions. Ileostomy or colostomy creation are sequelae of oncologic or emergency colorectal surgery, but their closure does not fall within the definition of oncologic or emergency surgery. The aim of this retrospective multicentre observational study is to report the impact of COVID-19 pandemic on the ostomy closure rate in Italy. Read More

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Airway Emergencies Due to Anterior Mediastinal T-Lymphoblastic Lymphoma Managed With Planned Extracorporeal Membrane Oxygenation and Endotracheal Stent: A Case Report and Literature Review.

Cureus 2022 Feb 1;14(2):e21799. Epub 2022 Feb 1.

Department of Pediatrics, Oita University Faculty of Medicine, Yufu, JPN.

Anterior mediastinal tumors can occasionally cause acute respiratory failure by compressing the trachea and bronchi. In such cases, sedative muscle relaxants during tracheal intubation can cause fatal complete tracheal obstruction. We encountered a 15-year-old male patient with T-lymphoblastic lymphoma (T-LBL) of the anterior mediastinum. Read More

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February 2022

Clinical factors predictive of recurrent febrile neutropenia in adult patients with acute leukemia.

Leuk Res Rep 2022 15;17:100296. Epub 2022 Feb 15.

Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Febrile neutropenia (FN) is considered an oncologic emergency in acute leukemia. There were 250 FN events in 124 hospitalized patients with hematologic malignancy. These data imply that two FN events may occur per patient, yet data on the prevalence, risk factors, and outcomes of recurrent FN in adult patients with leukemia are limited. Read More

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February 2022

Factors impacting posttraumatic growth in head-and-neck cancer patients with oncologic emergencies.

Support Care Cancer 2022 May 3;30(5):4515-4525. Epub 2022 Feb 3.

Department of Radiation Oncology and Proton and Radiation Therapy Center, Linkou Chang, Gung Memorial Hospital, Taoyuan, Taiwan.

Purpose: To identify factors associated with posttraumatic growth (PTG) of head-and-neck cancer squamous cancer (HNC) patients with oncologic emergencies (OE) within the first six months post-treatment.

Methods: We conducted a cross-sectional study of HNC patients in Taiwan from May 2019 to April 2021 using patient-reported outcomes. Patients were assessed for symptom distress, anxiety, fear of recurrence (FCR), and PTG. Read More

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COVID-19 lockdown: The relationship between trait impulsivity and addictive behaviors in a large representative sample of Italian adults.

J Affect Disord 2022 04 24;302:424-427. Epub 2022 Jan 24.

Department of Environmental Health Sciences, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.

Background: The importance of trait impulsivity in development, continuation and escalation of addictive behaviors has long been recognized.

Methods: A cross-sectional population-based survey was conducted during the COVID-19 lockdown on 6003 Italian adults aged 18-74 years, representative of the Italian general population, to investigate the relationship between impulsivity (Barratt Impulsiveness Scale - BIS) and selected addictive behaviors (gambling habits, smoking status, cannabis use, average alcohol daily use).

Results: A statistically significant relationship was found between motor impulsivity and starting/increasing drinking and increasing gambling (high vs. Read More

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Remote Monitoring of Patients With Hematologic Malignancies at High Risk of Febrile Neutropenia: Exploratory Study.

JMIR Form Res 2022 Jan 25;6(1):e33265. Epub 2022 Jan 25.

UCLA Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, United States.

Background: Febrile neutropenia is one of the most common oncologic emergencies and is associated with significant, preventable morbidity and mortality. Most patients who experience a febrile neutropenia episode are hospitalized, resulting in significant economic cost.

Objective: This exploratory study implemented a remote monitoring system comprising a digital infrared thermometer and a pulse oximeter with the capability to notify providers in real time of abnormalities in vital signs that could suggest early clinical deterioration and thereby improve clinical outcomes. Read More

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January 2022

[A Case of Superior Vena Cava Syndrome Due to Recurrent Breast Cancer Effectively Treated by Trastuzumab Deruxtecan].

Gan To Kagaku Ryoho 2022 Jan;49(1):88-90

Division of Medical Oncology, Tokyo Saiseikai Central Hospital.

A 64-year-old female underwent Bt+Ax surgery due to ER(-), PR(-), HER2(+), ycT3N1M0, Stage ⅢA right breast cancer. After cancer recured in the chest wall, whole-breast radiation therapy was performed, followed by ddAC, and T- DM1. After 12 courses of T-DM1, CT scan and physical findings showed no evidence of metastases, so chemotherapy was suspended with strict follow-up. Read More

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January 2022

Characteristics of unplanned hospitalisations among cancer patients in Singapore.

Ann Acad Med Singap 2021 12;50(12):882-891

Division of Supportive and Palliative Care, National Cancer Centre, Singapore.

Introduction: Cancer is a pervasive global problem with significant healthcare utilisation and cost. Emergency departments (EDs) see large numbers of patients with oncologic emergencies and act as "gate-keepers" to subsequent hospital admissions. A proportion of such hospital admissions are rapidly discharged within 2 days and may be potentially avoidable. Read More

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December 2021

Infantile mediastinal neuroblastoma presenting as an oncologic emergency: usefulness of serum-based gene amplification analysis for risk stratification.

BMJ Case Rep 2021 Dec 31;14(12). Epub 2021 Dec 31.

Department of Paediatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan.

We reported two infantile cases of mediastinal neuroblastoma with life-threatening tracheal obstructions presenting as oncologic emergencies that were successfully treated per tentative risk classification using serum-based gene amplification (MNA) analysis. Tentative risk stratification based on age, tumour location and serum-based MNA status may be useful in patients with neuroblastoma presenting as oncologic emergencies who require urgent therapy stratification but for whom tumor-based molecular diagnoses cannot be established. Read More

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December 2021

A Case of Tumor Lysis Syndrome Complicated by Disseminated Intravascular Coagulation - Case Reports of the LifePACT Critical Care Transport Team.

R I Med J (2013) 2021 Dec 1;104(10):12-14. Epub 2021 Dec 1.

Professor of Emergency Medicine, Medical Director, LifePACT; Director, Division of EMS, Warren Alpert Medical School of Brown University.

Hematologic/Oncologic emergencies are rarely seen in the critical care transport environment but must be recognized and treated without delay. We report such a patient transported from a referring hospital to a tertiary care center by the LifePACT team, a 52-year-old male with a history of acute myeloid leukemia (AML). The patient presented to the referring hospital with known laboratory test abnormalities, suffered cardiac arrest, was resuscitated, accepted for transfer to a tertiary care center, and LifePACT was requested to perform the transport. Read More

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December 2021

Forecasting outcomes after cholecystectomy in octogenarian patients.

Surg Endosc 2022 Jun 25;36(6):4479-4485. Epub 2021 Oct 25.

General and Oncologic Surgery, Morgagni - Pierantoni Hospital, AUSL Romagna, Forlì, Italy.

Background: Although gallstone disease increases with aging, elderly patients are less likely to undergo cholecystectomy. This is because age itself is a negative predictor after cholecystectomy. The ACS-NSQIP risk calculator can therefore help surgeons decide whether to operate or not. Read More

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Pancreaticobiliary Malignancies in the Emergency Room: Management of Acute Complications and Oncological Emergencies.

J Gastrointest Cancer 2021 Oct 14. Epub 2021 Oct 14.

Leeds Institute of Medical Research, St James' Institute of Oncology, St James' University Hospital, University of Leeds, Leeds, LS9 7TF, UK.

Background: Management of pancreaticobiliary (PB) malignancies remains a clinical challenge. In this review, we focus on the management of oncological emergencies in PB malignancies and the potential complication of associated therapeutic interventions.

Methods: Biobliographic review of current evidence on the management of oncological emergencies, their potential complications, as well as synthesis of recommendations was performed. Read More

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October 2021

Emergencies in oncology: an overview and practical suggestions.

Recenti Prog Med 2021 10;112(10):627-638

Division of Anesthesia and Pain Medicine, Istituto Nazionale Tumori - IRCCS Fondazione G. Pascale, Naples, Italy.

Oncologic emergencies are clinical situations that can lead to death in a short time (24-48 hours) if not quickly faced. In the clinical practice of the medical oncologist, such situations do not infrequently occur. The onset of oncologic emergencies may depend on the presence of cancer itself, the therapies carried out to counteract cancer, or the patient’s predisposition to develop such events. Read More

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October 2021

Gastrointestinal Surgical Emergencies in the Neutropenic Immunocompromised Patient.

J Gastrointest Surg 2021 12 10;25(12):3258-3264. Epub 2021 Sep 10.

Department of Surgery, Section of General Surgery and Surgical Oncology, University of Chicago, 5841 S. Maryland Ave, G 205, MC 5094, Chicago, IL, 60637, USA.

Surgeons encounter neutropenic patients through elective or emergency consultation with increasing regularity. As medical management continues to extend the lives of patients with benign hematologic diseases, hematologic malignancies, solid malignancies, or iatrogenic neutropenia, more patients are presenting with infectious complications caused and/or complicated by their neutropenia. This leaves surgeons in the difficult position of managing medically fragile patients with unusual presentations of common disease processes. Read More

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December 2021

Oncologic Emergencies.

AACN Adv Crit Care 2021 Sep;32(3):306-314

Garry J. Brydges is Director, Anesthesia Safety and Quality, Department of Anesthesiology, Division of Anesthesia, Critical Care and Pain Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.

A new cancer diagnosis is expected to affect approximately 1.9 million people in the United States in 2021. A small percentage of these patients will experience an emergent cancer-related complication. Read More

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September 2021

Prognostic Value of Procalcitonin, C-Reactive Protein, and Lactate Levels in Emergency Evaluation of Cancer Patients with Suspected Infection.

Cancers (Basel) 2021 Aug 13;13(16). Epub 2021 Aug 13.

Department of Emergency Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.

Cancer patients have increased risk of infections, and often present to emergency departments with infection-related problems where physicians must make decisions based on a snapshot of the patient's condition. Although C-reactive protein, procalcitonin, and lactate are popular biomarkers of sepsis, their use in guiding emergency care of cancer patients with infections is unclear. Using these biomarkers, we created a prediction model for short-term mortality in cancer patients with suspected infection. Read More

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Usefulness of a novel transarterial chemoinfusion plus external-beam radiation therapy for advanced hepatocellular carcinoma with tumor thrombi in the inferior vena cava and right atrium: Case study.

Cancer Rep (Hoboken) 2021 Aug 24:e1539. Epub 2021 Aug 24.

Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.

Background: Invasion beyond inferior vena cava (IVC) to right atrium (RA) is a rare complication in patients with advanced hepatocellular carcinoma (HCC), and results in fatal oncologic emergencies, including pulmonary embolism and right heart failure.

Aim: As there is no gold standard treatment for unresectable HCC with tumor thrombi involving IVC and RA, we considered it valuable to assess safety and efficacy of a combination of hepatic arterial infusion chemoembolization (HAIC) therapy and external-beam radiation therapy (EBRT).

Methods And Results: The "New FP" was chosen as the HAIC therapy, in which the enhanced permeation and retention effect was achieved using a cisplatin-Lipiodol suspension combined with continuous infusion of 5-fluorouracil (5-FU). Read More

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Oligometastatic non-small cell lung cancer: from biology to clinical practice.

Transl Lung Cancer Res 2021 Jul;10(7):3320-3323

Department of Intensive Care and Oncologic Emergencies & Thoracic Oncology, Institute Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium. (Email:

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Evaluation and Management of Genitourinary Emergencies in Patients with Cancer.

Emerg Med Int 2021 27;2021:4511968. Epub 2021 Jul 27.

Department of Emergency Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Background: Genitourinary emergencies in cancer patients are common. Most cancer treatments are administered in the outpatient setting, and patients with complications often visit the emergency department. However, there is no recent emergency medicine literature review focusing on genitourinary emergencies in the oncologic population. Read More

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Therapeutics for paediatric oncological emergencies.

Drugs Context 2021 23;10. Epub 2021 Jun 23.

Department of Paediatrics and Adolescent Medicine, Hong Kong Children's Hospital, Hong Kong.

Background: With advancements in the field of oncology, cancer survival rates have improved dramatically but modern cancer treatments also come with an increasing number of disease and treatment-associated complications. This article provides an updated narrative review on the pathophysiology, clinical presentations and latest management strategies for common paediatric oncological emergencies.

Methods: An extensive PubMed search of all human studies in the English literature was performed in Clinical Queries for different oncology syndromes and conditions using the following Medical Subject Headings: "tumour lysis syndrome", "hyperleukocytosis", "disseminated intravascular coagulation", "superior mediastinal syndrome", "superior vena cava syndrome", "sepsis", "severe inflammatory response syndrome", "acute respiratory distress syndrome", "posterior reversible encephalopathy syndrome" and "reversible posterior leukoencephalopathy syndrome". Read More

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Pediatric Hematologic and Oncologic Emergencies.

Emerg Med Clin North Am 2021 Aug 9;39(3):555-571. Epub 2021 Jun 9.

Department of Emergency Medicine, University of Maryland School of Medicine, 110 S. Paca Street, 6th Floor, Suite 200, Baltimore, MD 21201, USA. Electronic address: https://twitter.com/sbuidubbs.

Pediatric hematologic and oncologic emergencies are in 3 major categories: complications of hematologic disorders, emergencies associated with the new onset of cancers, and treatment-associated oncologic emergencies. The overall number of these patients remains low; however, the mortality associated with these diseases remains high despite significant advances in management. This article presents a review of the most commonly encountered pediatric hematologic and oncologic complications that emergency physicians and providers need to know. Read More

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