Search Our Scientific Publications & Authors

PLoS One 2020 10;15(7):e0235899. Epub 2020 Jul 10.

Department of Pediatric Surgery and Urology, Medical University of Wroclaw, Wroclaw, Poland.

Background: In the literature, no studies describe the use of laparoscopic techniques for inguinal hernia repair in canine clinical patients. The surgical technique-Percutaneous Internal Ring Suturing (PIRS) presented in this article is the world's first minimally invasive laparoscopic surgical technique for inguinal canal closure in dogs.

Aim: The aim of the presented study is to evaluate the possibility of employment of the laparoscopic PIRS technique in clinical practice as well as to technically evaluate its usefulness in the treatment of the inguinal hernia in dogs. Read More

Curr Health Sci J 2020 Jan-Mar;46(1):90-98. Epub 2020 Mar 31.

Department of Pathology, Emergency County Hospital, Craiova, University of Medicine and Pharmacy of Craiova, Romania.

Introduction: Sweet syndrome (SS), also denominated as acute febrile neutrophilic dermatosis, is a rare disease characterized by the sudden onset of painful, erythematous, firm skin lesions (papules, plaques, and nodules) which show, upon histologic examination, the presence of a diffuse infiltrate of mature neutrophils. The cutaneous manifestation typically involves the face, neck, trunk, and upper limbs and is associated with fever, general malaise, arthralgia.

Case Report: A female patient, 60 years old, attended the Dermatology Clinic due to the appearance of violaceous erythematous-oedematous infiltrated plaques, located on the face, neck, upper limbs, trunk and knees. Read More

J Pediatr 2020 Jul 3. Epub 2020 Jul 3.

Wisconsin Surgical Outcomes Research Program; Department of Surgery, University of Wisconsin - Madison.

Objectives: To characterize regional variation in the age of patients undergoing umbilical hernia repair to determine costs and subsequent care.

Study Design: We performed a cross-sectional descriptive study using a large convenience sample of United States employer-based insurance claims from July 2012 to December 2015. We identified children under 18 years undergoing uncomplicated (not strangulated, incarcerated, or gangrenous) umbilical hernia repair as an isolated procedure (ICD-9 procedure code 53. Read More

Obes Surg 2020 Jul 2. Epub 2020 Jul 2.

Endocrine, Metabolic and Bariatric Unit, General Surgery Department, Germans Trias i Pujol Hospital, Ctra de Canyet s/n, 08916, Badalona, Barcelona, Spain.

Background: Single anastomosis duodenoileal bypass with sleeve gastrectomy (SADI-s) is a well-known and accepted technique for extreme obesity but technically challenging in this group of patients and so frequently is performed as a laparoscopic staged procedure. Robotic devices such as Da Vinci® system may solve some limitations of laparoscopic surgery. The video shows a really totally robotic SADI-s (RTR-SADI-s) in a single stage on a patient with extreme morbid obesity and a non-reducible umbilical hernia. Read More

J Clin Ultrasound 2020 Jun 29. Epub 2020 Jun 29.

The Division of Maternal Fetal Medicine, The Department of Obstetrics and Gynecology, State University of New York (SUNY), Downstate Heath Sciences University, Brooklyn, New York, USA.

Liver herniation commonly associated with omphalocele occurs in only approximately 2.3% to 16% of fetuses with gastroschisis. Liver herniation in such cases is associated with considerably decreased survival rates (43% vs 97% with or without liver herniation, respectively). Read More

BMC Pediatr 2020 Jun 29;20(1):320. Epub 2020 Jun 29.

Department of Neonatology, Neonatal Biophysical Monitoring and Cardiopulmonary Therapies Research Unit, Poznan University of Medical Sciences, Poznan, Poland.

Background: Alveolar capillary dysplasia (ACD) is a rare cause of severe pulmonary hypertension and respiratory failure in neonates. The onset of ACD is usually preceded by a short asymptomatic period. The condition is refractory to all available therapies as it irreversibly affects development of the capillary bed in the lungs. Read More

J Am Osteopath Assoc 2020 Jul;120(7):476-478

Prostate cancer is the second most common cause of cancer death among US men. Metastasis typically occurs in the bone, lymph nodes, liver, and thorax. This case highlights a patient who was suspected of having prostate cancer several years before presenting to the emergency department with back pain and an umbilical hernia of increasing size. Read More

J Surg Case Rep 2020 Jun 19;2020(6):rjaa120. Epub 2020 Jun 19.

Department of Surgery, St. Johns Episcopal Hospital, Far Rockaway, New York, NY, USA.

Multifocal endometriosis found outside of the pelvis is very rare. We present here a case of endometriosis found in the pelvis, appendix and umbilicus. A 52-year-old female had a previous umbilical hernia repair, and years later started to develop a recurrent umbilical mass. Read More

Adv Pediatr 2020 Aug 26;67:131-143. Epub 2020 May 26.

Section of Pediatric Surgery, Department of Surgery, University of Michigan, Mott Children's Hospital, 1540 East Hospital Drive SPC 4217, Ann Arbor, MI 48109 - 4217, USA; Division of Vascular and Interventional Radiology, Department of Radiology, University of Michigan, Mott Children's Hospital, 1540 East Hospital Drive SPC 4217, Ann Arbor, MI 48109 - 4217, USA. Electronic address:

Am J Med Genet A 2020 Jun 26. Epub 2020 Jun 26.

Virginia Tech Carilion School of Medicine, Roanoke, Virginia, USA.

Baraitser-Winter cerebrofrontofacial syndrome (BWCFF) is a rare autosomal dominant developmental disorder associated with missense mutations in the genes ACTB or ACTG1. The classic presentation of BWCFF is discerned by the combination of unique craniofacial characteristics including ocular coloboma, intellectual disability, and hypertelorism. Congenital contractures and organ malformations are often present, including structural defects in the brain, heart, renal, and musculoskeletal system. Read More

Nagoya J Med Sci 2020 May;82(2):345-354

Department of Obstetrics and Gynecology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Congenital diaphragmatic hernia (CDH) is a congenital anomaly characterized by a defect in the diaphragm. Despite the recent improvements in its treatment, CDH is associated with a high rate of neonatal mortality, which is often related to pulmonary hypoplasia (PH) as well as pulmonary hypertension. A better understanding of the underlying pathological mechanisms of PH in CDH could help establish a new treatment to improve its prognosis. Read More

Case Rep Med 2020 9;2020:4578912. Epub 2020 Jun 9.

Department of Hematology, Complejo Asistencial Universitario de Salamanca and IBSAL, Salamanca, Spain.

Omphalocele is a congenital malformation of the abdominal wall consisting of a protrusion of the abdominal contents at the base of the umbilical cord. It has a high association with genetic and structural defects; however, if the latter is ruled out, its prognosis improves significantly. Prenatal diagnosis has a key role in this condition as omphalocele can be diagnosed by ultrasound in the first trimester scan, enabling a coordinated approach strategy to achieve the best perinatal results. Read More

Hernia 2020 Jun 20. Epub 2020 Jun 20.

Unit of General Surgery, Department of Surgery, ASST Santi Paolo e Carlo, San Carlo Borromeo Hospital, Via Pio II n.3, 20153, Milan, Italy.

Purpose: Diastasis recti (DR) is characterized by an alteration of the linea alba with increased inter-recti distance (IRD). It is more frequent in females, and when symptomatic or associated with midline hernia it needs to be surgically repaired. This retrospective study aims to demonstrate how an overall approach to DR leads to good results in terms of functional and morphological outcomes and quality of life (QoL). Read More

J Laparoendosc Adv Surg Tech A 2020 Jun 19. Epub 2020 Jun 19.

Department of Surgery, San Joaquin General Hospital, French Camp, California, USA.

Umbilical hernias and acute appendicitis are common general surgical problems, but an appendix incarcerated in an umbilical hernia is quite rare. We present a case of such and briefly review the available literature on the topic. We conclude that future authors should include a minimum set of information in such case reports or case series so that readers can gain as much as possible from our collective experience with this uncommon problem. Read More

Alcohol Alcohol 2020 Jun 19. Epub 2020 Jun 19.

Nottingham Digestive Diseases Biomedical Research Centre, National Institute for Health Research (NIHR), Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, NG7 2UH, UK.

Aims: This meta-analysis aimed to define the perioperative risk of mortality in patients with alcoholic liver disease (ALD) undergoing extrahepatic gastrointestinal surgery.

Methods: Systematic searches of Embase, Medline and CENTRAL were undertaken to identify studies reporting about patients with ALD undergoing extrahepatic gastrointestinal surgery published since database inception to January 2019. Studies were only considered if they reported on mortality as an outcome. Read More

Surg Endosc 2020 Jun 15. Epub 2020 Jun 15.

Department of Surgery, Hospital Universitario Clínico San Carlos, C/Profesor Martín Lagos SN, 28040, Madrid, Spain.

Background: Trocar-site incisional hernia (TSIH) after laparoscopic surgery has been scarcely studied. TSIH incidence and risk factors have never been properly studied for laparoscopic colorectal surgery.

Methods: A retrospective analytic study in a tertiary hospital was performed including patients who underwent elective laparoscopic colorectal surgery between 2014 and 2016. Read More

Hernia 2020 Jun 15. Epub 2020 Jun 15.

Center for Abdominal Core Health, Digestive Disease and Surgery Institute, Cleveland Clinic Foundation, Cleveland, OH, USA.

Purpose: Expert consensus recommends that all ventral hernias be repaired prior to, or concomitantly with, peritoneal dialysis (PD) catheter insertion. We examined the clinical outcomes of patients undergoing initial PD catheter insertion, with asymptomatic ventral hernias that were not repaired and rather managed using a watchful waiting approach.

Methods: A single-center, retrospective review of patients undergoing PD catheter insertion from 2005-2019 was performed. Read More

Ann Med Surg (Lond) 2020 Jul 8;55:294-299. Epub 2020 Jun 8.

Department of General, Visceral and Cancer Surgery, Helios Klinikum Berlin-Buch, Schwanebecker Chaussee 50, 13125, Berlin, Germany.

Purpose: Patients suffering from a ventral hernia can be treated by laparoscopic ventral hernia repair (VHR) with the intraperitoneal onlay mesh (IPOM) technique. To reduce early postoperative pain and the analgesic cumulative need for medication (CNM), the transversus abdominis plane (TAP) block has recently been investigated and implemented in hernia surgery. We aimed to investigate its impact when conducting a VHR in IPOM technique. Read More

Rozhl Chir 2020 ;99(5):207-211

Introduction: Repairs of umbilical and epigastric hernias are common surgical procedures; the choice of the surgical method generally depends on the size of the hernial sac and fascial defect.

Methods: Data of patients operated on for umbilical or epigastric hernias in our hospital during two years were assessed retrospectively. The study group included 264 patients; 212 had an umbilical hernia and 52 had an epigastric hernia. Read More

Cureus 2020 May 12;12(5):e8075. Epub 2020 May 12.

Surgery, Beaumont Health, Dearborn, USA.

Umbilical hernia is a common cause for patient presentation to the surgeon, often on a nonemergent basis for a bulge at or lateral to the umbilicus but occasionally under emergency circumstances for pain or bowel obstruction when the hernia contents become incarcerated or strangulated. Risk factors for umbilical hernia include female gender, obesity, and ascites. A defect in the abdominal wall fascia at the umbilicus allows the preperitoneal adipose tissue, omentum, or small or large bowel to protrude through the defect. Read More

J Obstet Gynaecol Res 2020 Jun 15. Epub 2020 Jun 15.

Department of Obstetrics and Gynecology, School of Medicine, Kurume University, Kurume, Japan.

We observed a case of classic cloacal exstrophy (CE) from 17 to 30 weeks' gestation. At 17 weeks, an omphalocele and single umbilical artery (SUA) were diagnosed with a normal female karyotype on amniocentesis. A pelvic cystic adjacent to SUA, considered to be the bladder at 17 weeks, became swollen to form double cysts at 25 weeks. Read More

Arch Iran Med 2020 Jun 1;23(6):403-408. Epub 2020 Jun 1.

Department of General Surgery, Erciyes University Medical Faculty, Melikgazi, Kayseri, Turkey.

Background: Our aim was to investigate the pathologies in the hernia sac in adults, and the frequency of malignancy as well as to confirm the necessity of maintaining the current applications in histological examination of the hernia sac.

Methods: Patients who were operated for hernia in our clinic from 2013 to 2019 were included in the study. Patient data were evaluated retrospectively. Read More

Int J Surg Case Rep 2020 Jun 6;72:99-103. Epub 2020 Jun 6.

Department of Obstetrics and Gynecology, Tottori University School of Medicine, 36-1 Nishicho, Yonago, Tottori, 683-5804, Japan.

Introduction: Panniculectomy is regarded as an effective approach in highly obese patients with endometrial cancer to improve surgical access or space of the surgical field.

Presentation Of Case: A 66-year-old nulliparous woman was brought in from another hospital to our institute for newly diagnosed endometrial carcinoma. The patient was 158 cm in height and weighed 135. Read More

Arch Gynecol Obstet 2020 Aug 12;302(2):377-382. Epub 2020 Jun 12.

Department of Neuroscience, Reproductive Sciences and Dentistry, School of Medicine, University of Naples Federico II, Naples, Italy.

Background: Gallbladder duplication is a rare anatomic anomaly characterized by the presence of an accessory gallbladder.

Objective: To appraise the prevalence and significance of prenatal diagnosis of duplication of gallbladder in a multicenter study.

Methods: This was a multicenter case series with literature review. Read More

Ann Med Surg (Lond) 2020 Jul 25;55:244-251. Epub 2020 May 25.

Department of Digestive Diseases & Gastrointestinal Surgery, Brighton & Sussex University Hospitals NHS Trust, The Royal Sussex County Hospital, Eastern Road, Brighton, West Sussex, BN2 5BE, United Kingdom.

Aims: The objective of this article is to compare the surgical outcomes for epigastric port or umbilical port retrieval of the gallbladder (GB) following laparoscopic cholecystectomy (LC).

Methods: The data retrieved from the published randomized, controlled trials (RCT) comparing the surgical outcomes for epigastric port or umbilical port retrieval of the GB following LC was analysed using the principles of meta-analysis. The summated outcome of continuous variables was expressed as standardized mean difference (SMD) and dichotomous data was presented in odds ratio (OR). Read More

Reg Anesth Pain Med 2020 Jun 9. Epub 2020 Jun 9.

Division of Pediatric Anesthesiology, Department of Anesthesiology, Emory University School of Medicine, Atlanta, GA, United States.

Int J Surg Case Rep 2020 May 16. Epub 2020 May 16.

Grant Government Medical College & Sir, JJ Group of Hospitals, Mumbai, India.

Introduction: The work has been reported in line with the SCARE criteria. The most common retained foreign body during surgery is woven cotton surgical sponge, which includes both laparotomy pads and smaller sponges. Sponges are easily retained because of their ubiquitous use, relatively small size and when soaked in blood, sponges conform to and can be difficult to distinguish from surrounding tissues. Read More

Hernia 2020 Jun 3. Epub 2020 Jun 3.

Department of Surgery, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY, USA.

Introduction: Socioeconomic factors predispose certain populations to an increased exposure to emergent operative procedures. The aim of this study is to evaluate the role socioeconomic factors play in emergent repairs of inguinal, ventral and umbilical hernias.

Methods: The SPARCS database was used to identify all patients undergoing emergent ventral hernia repair (EVR), emergent inguinal hernia repair (EIR), and emergent umbilical hernia repair (EUR) between 2008 and 2015. Read More

Anticancer Res 2020 Jun;40(6):3445-3451

Department of Surgery, The Jikei University School of Medicine, Tokyo, Japan.

Background/aim: Umbilical defunctioning ileostomy (UDI) spares one incision, which may reduce the overall incidence of incisional hernia. Our aim was to evaluate the occurrence and risk factors of incisional hernias between UDI and conventional defunctioning ileostomy (CDI) after ileostomy closure.

Patients And Methods: Incidence of incisional hernia after ileostomy closure was compared between UDI (n=51) and CDI (n=86) groups. Read More

Neoreviews 2020 Jun;21(6):e383-e391

Division of Pediatric Surgery, Children's Hospital, University of Missouri, Columbia, MO.

The 2 most common congenital abdominal wall defects are gastroschisis and omphalocele. Both are usually diagnosed prenatally with fetal ultrasonography, and affected patients are treated at a center with access to high-risk obstetric services, neonatology, and pediatric surgery. The main distinguishing features between the 2 are that gastroschisis has no sac and the defect is to the right of the umbilicus, whereas an omphalocele typically has a sac and the defect is at the umbilicus. Read More

J Pediatr Surg 2020 May 3. Epub 2020 May 3.

Cincinnati Children's Hospital Medical Center, Division of Pediatric General and Thoracic Surgery, Cincinnati, OH, USA.

Background/purpose: Morbidity and mortality in the giant omphalocele population is complicated by large abdominal wall defects, physiologic aberrancies, and congenital anomalies. We hypothesized different anomalies and treatment types would affect outcomes.

Methods: A 2009-2018 retrospective chart review of giant omphaloceles was performed. Read More

Asian J Endosc Surg 2020 May 28. Epub 2020 May 28.

Department of Surgery, Nara Medical University, Kashihara, Japan.

Introduction: Laparoscopic inguinal hernia repair is reported to be associated with lower postoperative pain than open repair. However, in the actual clinical setting, some patients experience relatively severe pain. This study aimed to elucidate surgical factors that affect pain after transabdominal preperitoneal (TAPP) repair. Read More

Surgery 2020 May 24. Epub 2020 May 24.

Department of Surgery and Centre for Surgical Science, Zealand University Hospital, Denmark.

Background: Smoking and obesity are well-known risk factors for surgical site infection, but it is unknown whether these factors influence outcomes after repair of small umbilical and epigastric hernias with defects ≤2 cm. The aim of this study was to evaluate whether smoking and obesity are associated with readmission, reoperation for complications, and recurrence rates after elective repair of small umbilical and epigastric hernias.

Methods: Data on hernia type, size, repair method, smoking status, and body mass index after elective repair were available from the Danish Hernia Database from January 2017 through December 2018. Read More

Hernia 2020 May 23. Epub 2020 May 23.

Center for Abdominal Core Health, Digestive Disease and Surgery Institute, The Cleveland Clinic Foundation, 9500 Euclid Avenue, A-100, Cleveland, OH, 44195, USA.

Purpose: The most common techniques used to repair umbilical hernias are open and laparoscopic. As the obesity epidemic in the United States is growing, it is essential to understand how this morbidity affects umbilical hernia repairs. This study compares laparoscopic versus open umbilical hernia repairs in obese patients. Read More

Surg Endosc 2020 May 20. Epub 2020 May 20.

Department of Gastroenterological Surgery, Yokohama City University Graduate School of Medicine, 3-9, Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.

Background: The short-term results of single-incision laparoscopic colectomy (SILC) showed the safety, feasibility, and effectiveness when performed by skilled laparoscopic surgeons. However, the long-term complications, such as SILC-associated incisional hernia, have not been evaluated. The aim of this study was to determine the incidence of incisional hernia after SILC compared with multi-port laparoscopic colectomy (MPC) for colon cancer. Read More

Surg Technol Int 2020 May;36:99-104

Introduction: Laparoscopic inguinal hernia repair has certain advantages over open repair including less pain and earlier return to normal activity. Robotic surgery adds high definition visualization and articulating instruments. This enhanced dexterity can make laparoscopic hernia repair more refined while obtaining a critical view of the myopectineal orifice that should lead to fewer recurrences and complications. Read More

World J Clin Cases 2020 May;8(9):1721-1728

Department of General Surgery, the Second Affiliated Hospital of Nanjing Medical University, Nanjing 2l0011, Jiangsu Province, China.

Background: Ventral hernia, also known as incisional hernia, is a common complication of previous surgery. The contents of ventral hernia may include omentum, preperitoneal fat, small intestine or colon. However, ventral hernia with protrusion of more than two parenchymal organs simultaneously is extremely rare, and its repair is very complex and difficult. Read More

Minim Invasive Ther Allied Technol 2020 May 19:1-7. Epub 2020 May 19.

Department of Pediatric Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, P. R. China.

The purpose of this study was to summarize the clinical experience with laparoscopic percutaneous extraperitoneal closure of the internal ring using an epidural needle for inguinal hernias in girls. A total of 462 girls with inguinal hernias participated in this study from January 2013 to June 2019. Laparoscopic percutaneous extraperitoneal closure of the internal ring an epidural needle was used to treat these patients. Read More

Rev Esp Anestesiol Reanim 2020 May 13. Epub 2020 May 13.

Servicio de Anestesiología y Reanimación, Hospital Gregorio Marañón, Madrid, España.

Introduction: Postoperative management of patients with the congenital growth disorder Beckwith-Wiedemann syndrome (BWS) can be complicated. The main clinical manifestations of the syndrome are macroglossia - which may hamper airway management -, prematurity, hemihypertrophy, omphalocele, embryonal tumours and episodes of neonatal hypoglycaemia.

Objective: Our main objective is to describe the perioperative management and potential anaesthetic complications in paediatric patients with BWS undergoing glossectomy. Read More

Int J Surg Case Rep 2020 11;70:78-82. Epub 2020 May 11.

Clinic of Surgical Infections, Riga East University Hospital, Riga, Latvia; Faculty of Medicine, University of Latvia, Riga, Latvia. Electronic address:

Introduction: The aim of the presentation is to demonstrate a new conservative approach for the salvage treatment of the infected hernia mesh.

Methods: Three patients with polypropylene mesh infection following an open umbilical and incisional hernia repair performed by placing the mesh in the onlay position are presented. The infection manifested itself with a systemic inflammatory response and an infected fluid collection surrounding the mesh. Read More

Ned Tijdschr Geneeskd 2020 04 30;164. Epub 2020 Apr 30.

Zuyderland Medisch Centrum, afd. Chirurgie, Heerlen.

A 57 year old woman with a history of liver cirrhosis and ascites presented with serous exudate spontaneously leaking from a ruptured umbilical hernia, also known as Flood syndrome. This syndrome is a rare complication of decompensated liver cirrhosis and is associated with high mortality. In this specific case, there was also omentum protruding through the umbilical hernia which limited the outflow of ascites. Read More

Toxicol Sci 2020 May 11. Epub 2020 May 11.

Division of the National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, NC.

Human exposure to boron occurs primarily through diet and drinking water sources. Animal studies have found that reduced fetal weight following gestational exposure to boron (as boric acid) is the most sensitive toxicological effect. However, recent studies suggest that newborns in areas with elevated boron in drinking water may receive levels of exposure that exceed the US EPA oral reference dose for B. Read More

Am Surg 2020 04;86(4):e220

PLoS One 2020 7;15(5):e0232542. Epub 2020 May 7.

Programa de Pós-graduação em Zootecnia, Centro de Educação Superior do Oeste, Universidade do Estado de Santa Catarina, UDESC, Chapecó, Santa Catarina, Brazil.

Umbilical hernia (UH) is one of the most frequent defects affecting pig production, however, it also affects humans and other mammals. UH is characterized as an abnormal protrusion of the abdominal contents to the umbilical region, causing pain, discomfort and reduced performance in pigs. Some genomic regions associated to UH have already been identified, however, no study involving RNA sequencing was performed when umbilical tissue is considered. Read More

Chirurgia (Bucur) 2020 Mar-Apr;115(2):140-147

The risk of developing an abdominal wall hernia is high in the cirrhotic patient, due to the association of ascites, hypoalbuminemia and amyotrophy in connection with undernutrition frequently associated with cirrhosis. Thus, almost 20% of cirrhotic patients develop an umbilical hernia. Parietal surgery is more at risk in cirrhotic patients and its indications must be discussed on a case-by-case basis. Read More

Int J Surg Protoc 2020 4;21:27-31. Epub 2020 Apr 4.

Division of Digestive Surgery, University Hospitals of Geneva, Rue Gabrielle-Perret-Gentil 4, 1211 Genève 14, Switzerland.

Background: The objective of the present study is to compare the outcomes open PVHR and robotic PVHR.

Methods/design: The present study will be a randomized single-blinded controlled trial with intention-to-treat analysis comparing robotic PVHR to open PVHR in adult patients undergoing elective PVHR with a defect ranging between 1-5 cm. Patient refusing to participate, not able to give informed consent, with history of intra-abdominal surgery contraindicating a robotic surgical approach will be excluded. Read More

Pediatr Int 2020 May 2. Epub 2020 May 2.

Department of Plastic Surgery, Ina Central Hospital; Ina, Nagano, Japan.

Background: This study was conducted to evaluate the incidence and early predictive factors of the development of protuberant umbilicus in pediatric umbilical hernia patients.

Methods: In this retrospective visual and chart review, patients younger than 3 months with umbilical hernias who initially visited Ina Central Hospital from April 2011 to March 2017 and were followed until they started to walk (at the age of 1 year) were evaluated. The umbilici of the patients at the age of 1 year were classified into two types based on the appearance: concave and protuberant umbilici. Read More

Ital J Pediatr 2020 Apr 29;46(1):55. Epub 2020 Apr 29.

Department of Gastroenterology, Hepatology and Nutrition, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, 200062, China.

Background: Beckwith-Wiedemann syndrome (BWS) is a genetic overgrowth disorder with variable clinical features and cancer predisposition. In this study, we aim to characterize the clinical features and molecular defects of BWS patients in China.

Methods: Thirty-one patients with clinical suspicion of BWS were retrospectively recruited to the study from Shanghai Children's Hospital between January 2014 and December 2017. Read More