14,668 results match your criteria Omental Torsion


Addressing the empty pelvic syndrome following total pelvic exenteration: does mesh reconstruction help?

Colorectal Dis 2018 Dec 7. Epub 2018 Dec 7.

Department of Colorectal Surgery, Royal Prince Alfred Hospital, Sydney, Australia.

Aim: Perineal wound complications and pelvic abscesses remain a major source of morbidity after total pelvic exenteration. The void created in the pelvis after these multi-visceral resections leads to fluid accumulation and translocation of bowel within the pelvic cavity, which may increase the risk of pelvic abscess, perineal fluid discharge with perineal wound dehiscence and prolonged ileus. This study describes a novel technique using degradable synthetic mesh with overlying omentum to preclude small bowel and fill the empty space after total pelvic exenteration, and aimed to investigate the rate of pelvic abscess and perineal wound-related complications in this group. Read More

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December 2018

Successful treatment using percutaneous drainage for aortic arch prosthetic graft infection.

J Cardiol Cases 2014 Sep 25;10(3):94-96. Epub 2014 Jun 25.

Department of Cardiovascular Surgery, Tokyo Medical University Hospital, Tokyo, Japan.

Prosthetic graft infection in the ascending aorta or aortic arch is a life-threatening complication. Redo graft replacement is also associated with high mortality and morbidity rates. Conservative treatments without graft removal recently developed as alternatives to conventional surgical approach have been reported with successful outcomes. Read More

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September 2014

Development of insulin resistance in Nischarin mutant female mice.

Int J Obes (Lond) 2018 Dec 13. Epub 2018 Dec 13.

Department of Biochemistry and Molecular Biology, LSUHSC School of Medicine, New Orleans, LA, 70112, USA.

Background/objectives: NISCH-STAB1 is a newly identified locus correlated to human waist-hip ratio (WHR), which is a risk indicator of developing obesity-associated diabetes. Our previous studies have shown that Nisch mutant male mice increased glucose tolerance in chow-fed conditions. Thus we hypothesized that Nisch mutant mice will have changes in insulin resistance, adipocytes, hepatic steatosis when mice are fed with high-fat diet (HFD). Read More

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December 2018

Internal Hernia Associated with Colostomy After Laparoscopic Surgery for Rectal Malignancy: A Report of 3 Thought-Provoking Cases.

Am J Case Rep 2018 Dec 14;19:1488-1494. Epub 2018 Dec 14.

Department of Digestive Surgery, Tenri Hospital, Tenri, Nara, Japan.

BACKGROUND Colostomy creation via intraperitoneal route is often performed during laparoscopic Hartmann's operation or abdominoperineal resection (APR). Herein, we report 3 rare cases of internal hernia associated with colostomy (IHAC). CASE REPORT The first case involved a 70-year-old man with IHAC after laparoscopic APR. Read More

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December 2018

Obstructive ileus caused by metal staples 6 years after the initial surgery: A case report.

Medicine (Baltimore) 2018 Dec;97(49):e13426

Department of Colorectal Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Rationale: Complete small bowel obstruction (SBO) is a common surgical emergency often resulting from adhesive bands installed after a surgical procedure. However, SBO caused by surgical staples used in a previous operation is unusual. Herein, we report a rare case of adhesive ileus induced by surgical staples. Read More

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December 2018

Adult Bochdalek Hernia with Organo-Axial Gastric Volvulus: Misdiagnosed as Hydropneumothorax.

Acta Medica (Hradec Kralove) 2018 ;61(3):108-110

Department of Surgery, University College of Medical Sciences and Guru Teg Bahadur Hospital, University of Delhi, Delhi, India.

Bochdalek hernia (BH) in an adult may manifest clinically with a myriad of abdominal or chest symptoms or a combination of them. Diagnosis of an adult BH is usually delayed in view of rarity of the lesion and its varied presentation. A 30-year-old adult gentleman presented to us with a left thoracostomy which was draining pus and ingested food particles. Read More

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January 2018

A new theory interprets the development of a retraction pocket as a natural self-healing process.

Eur Arch Otorhinolaryngol 2018 Dec 12. Epub 2018 Dec 12.

Department of ORL, University Clinic Cologne, Kerpenerstr. 62, 50937, Cologne, Germany.

Purpose: The thesis that cholesteatoma evolves from a retraction pocket is widely accepted today. Yet, its prime etiology, the question of what triggers the invagination of healthy skin, still remains unclear despite centuries of investigations into the origin of cholesteatoma. A new idea interprets the horizontal migration of skin into the middle ear cavities as a self-healing process, curing an underlying inflammation in the tympanic cavity, through the overgrowth and contact with immunologically active tissue. Read More

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December 2018

Laparoscopic repair of a perforated duodenal ulcer: another use of a round ligament flap.

Wideochir Inne Tech Maloinwazyjne 2018 Dec 30;13(4):542-545. Epub 2018 May 30.

Department of Digestive Surgery, Amiens University Hospital, Amiens, France.

Management of a perforated duodenal ulcer is most commonly performed by laparoscopy and consists of suture of the perforation after performing lavage of the peritoneal cavity. In most cases, a flap is created, and an omental flap is usually the preferred choice because of its simplicity and its proximity to the site of duodenal perforation. However, in some cases, the greater omentum cannot be used due to the severity of peritonitis or due to previous surgical removal. Read More

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December 2018

Collagenous Spherulosis in Well-Differentiated Papillary Mesothelioma in a Female With Multilocular Peritoneal Inclusion Cysts.

Int J Surg Pathol 2018 Dec 6:1066896918816815. Epub 2018 Dec 6.

1 Rashid Hospital, Dubai, UAE.

Multilocular peritoneal inclusion cysts are mesothelial tumor-like lesions with or without small foci of florid papillary mesothelial hyperplasia that might simulate serous epithelial papillary lesions or well-differentiated papillary mesothelioma (WDPM) of the peritoneum. The papillary cores in papillary mesothelial hyperplasia and in WDPM display a variety of different histomorphologic features. To our knowledge, collagenous spherulosis in WDPM was not previously described or illustrated in the literature. Read More

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December 2018

[Liver bud transplantation in rats].

Magy Seb 2018 Dec;71(4):163-169

Department of Organ Fabrication, Keio University School of Medicine 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.

Introduction: Research has made progress in organ fabrication using an extracellular matrix, cell sheets, or organoids. Human liver tissue has been constructed using a 3-dimensional (3D) bioprinter and showed evidence that an in vitro generated liver bud was reformed in a rodent liver model. This study describes the stages of development of rat fetal organs and liver structure and reviews recent progress in liver organoid transplantation. Read More

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December 2018

Unusual bilateral ureter strangulation by fibrous tissue after perineal hernia repair in a dog.

Open Vet J 2018 19;8(4):441-444. Epub 2018 Nov 19.

Hokkaido University Veterinary Teaching Hospital, Kita 19, Nishi 10, Kita-ku, Sapporo, Hokkaido 060-0819, Japan.

A 10-year-old castrated male cross-breed dog was referred for the repair of perineal hernia with bladder retroflexion and a mass lesion in the hernial sac. Surgical treatment was performed and the mass was identified as degenerated adipose tissue that was suspected to be derived from the omentum. The hernial contents were reduced without difficulty, and the dog exhibited a normal recovery. Read More

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November 2018

Effects of Weight Loss on Glutathione Peroxidase 3 Serum Concentrations and Adipose Tissue Expression in Human Obesity.

Obes Facts 2018 Dec 11;11(6):475-490. Epub 2018 Dec 11.

Department of Medicine, University of Leipzig, Leipzig,

Background/aims: Altered expression and circulating levels of glutathione peroxidase 3 (GPX3) have been observed in obesity and type 2 diabetes (T2D) across species. Here, we investigate whether GPX3 serum concentrations and adipose tissue (AT) GPX3 mRNA expression are related to obesity and weight loss.

Methods: GPX3 serum concentration was measured in 630 individuals, including a subgroup (n = 293) for which omental and subcutaneous (SC) GPX3 mRNA expression has been analyzed. Read More

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December 2018
1 Read

Cancer overturned: Endometrioma mimicking granulosa cell tumor and the importance of FOXL2 analysis.

Gynecol Oncol Rep 2019 Feb 22;27:8-10. Epub 2018 Nov 22.

Department of Obstetrics and Gynecology, Division of Gynecology and Gynecologic Subspecialties, University of Wisconsin Hospital and Clinics, Madison, WI, United States.

Background: Various ovarian neoplasms may show histological findings that are morphologically indistinguishable from adult granulosa cell tumor (AGCT).

Case Presentation: A 36 year-old women presented with left lower extremity pain and numbness. Ultrasound revealed a 10 cm left adnexal mass treated with ovarian cystectomy. Read More

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February 2019

Bioengineered functional humanized livers: An emerging supportive modality to bridge the gap of organ transplantation for management of end-stage liver diseases.

World J Hepatol 2018 Nov;10(11):822-836

Central Laboratory for Stem Cell Research and Translational Medicine, Centre for Liver Research and Diagnostics, Deccan College of Medical Sciences, Kanchanbagh, Hyderabad 500058, Telangana, India.

End stage liver diseases (ESLD) represent a major, neglected global public health crisis which requires an urgent action towards finding a proper cure. Orthotropic liver transplantation has been the only definitive treatment modality for ESLD. However, shortage of donor organs, timely unavailability, post-surgery related complications and financial burden on the patients limits the number of patients receiving the transplants. Read More

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November 2018

[Thrombotic microangiopathy developing subsequent to tocilizumab therapy in a patient with TAFRO syndrome].

Rinsho Ketsueki 2018 ;59(11):2432-2437

Department of Pathology, Hakodate Municipal Hospital.

We report a case of a 60-year-old male who presented with fever and anasarca as well as hepatosplenomegaly, general lymphadenopathy, and disseminated intravascular coagulation (DIC), and was, therefore, admitted to our hospital. In addition, the patient suffered from respiratory failure and renal dysfunction and had pleural effusion and ascites. The pathological diagnosis from lymph node biopsy suggested multicentric Castleman's disease of the plasma cell type; however, the presence of high IL-6 levels, myelofibrosis, thrombocytopenia, anasarca, renal dysfunction, and hepatosplenomegaly led to a definitive diagnosis of TAFRO syndrome. Read More

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January 2018

Impaired Glucocorticoid Suppression of TGFβ Signaling in Human Omental Adipose Tissues Limits Adipogenesis and May Promote Fibrosis.

Diabetes 2018 Dec 7. Epub 2018 Dec 7.

Diabetes Obesity and Metabolism Institute, Icahn School of Medicine at Mount Sinai, New York, New York.

Visceral obesity is associated with insulin resistance and higher risk of type 2 diabetes and metabolic diseases. A limited ability of adipose tissues to remodel through the recruitment and differentiation of adipose stem cells (ASCs) is associated with adipose tissue inflammation and fibrosis and the metabolic syndrome. We show that the lower adipogenesis of omental (Om) compared to abdominal subcutaneous (Abdsc) ASCs was associated with higher secretion of TGFβ ligands that acted in an autocrine/paracrine loop to activate SMAD2 and suppress adipogenesis. Read More

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December 2018

Minimal invasive laparoscopic harvest of the greater omental flap for Fournier's gangrene scrotal reconstruction.

J Plast Reconstr Aesthet Surg 2018 Nov 15. Epub 2018 Nov 15.

Department of Plastic and Reconstructive Surgery National Cancer Institute of Peru (INEN). Lima, Peru.

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November 2018

Encapsulating Peritoneal Sclerosis: The Abdominal Cocoon.

Radiographics 2018 Dec 7:180108. Epub 2018 Dec 7.

From the Departments of Radiology (M.S., A.L., N.K.), Histopathology (A.B.), General Surgery (T.D.Y.), and Gastroenterology (R.K., S.K.S.), PGIMER, Chandigarh, India; and the Abdominal Imaging Section, Department of Medical Imaging, The Ottawa Hospital, University of Ottawa, 1053 Carling Ave, Ottawa, ON, Canada, K1Y 4E9 (S.K., S.N., A.M.S.).

Encapsulating peritoneal sclerosis (EPS) is a rare but serious condition that results in (a) encapsulation of bowel within a thickened fibrocollagenous peritoneal membrane and (b) recurrent episodes of bowel obstruction. Although described by various names in the literature, the preferred term is encapsulating peritoneal sclerosis because it best describes the morphologic and histologic changes in this disorder. The etiology of EPS is multifactorial, with a wide variety of implicated predisposing factors that disrupt the normal physiologic function of the peritoneal membrane-prime among these factors being long-term peritoneal dialysis and bacterial peritoneal infections, especially tuberculosis. Read More

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December 2018

Effect of varying the crosslinking degree of a pericardial implant with oligourethane on the repair of a rat full-thickness abdominal wall defect.

J Biomater Appl 2018 Dec 10:885328218817890. Epub 2018 Dec 10.

1 División de Ciencias Ingenierías, Universidad de Guanajuato, León Guanajuato, Mexico.

The stability and bioactivity of biologic implants rely mainly on the control of the crosslinking process of collagen. However, the most common methods have no control on the crosslinking degree producing it excessively. This study outlines the role of crosslinking of collagen-based implants with oligourethane on the host response following reconstruction of a rat full-thickness abdominal wall defect. Read More

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December 2018

Practice patterns of surgery for advanced ovarian cancer: analysis from international surveys.

Jpn J Clin Oncol 2018 Dec 6. Epub 2018 Dec 6.

Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Republic of Korea.

Background: We investigated the practice patterns of surgery for advanced ovarian cancer (AOC) through relevant international surveys.

Methods: After searching for 878 studies on surgery for AOC till 2017, we extracted 18 questions with similar query and answer formats from eight studies. Among them, 5 and 13 were classified as comprehensive and procedure information. Read More

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December 2018
5 Reads

[Analysis of clinical features and prognostic factors on reoperation patients with postoperative recurrence or metastasis of gastrointestinal stromal tumor].

Zhonghua Wei Chang Wai Ke Za Zhi 2018 Nov;21(11):1274-1279

Ward III Gastrointestinal Surgery, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai Institute of Digestive Surgery, Shanghai 200025,

Objective: To investigate the clinical characteristics and prognostic factors of reoperation patients with postoperative recurrence or metastasis of gastrointestinal stromal tumor (GIST).

Methods: A retrospective case-control study was performed on the clinical data of 31 patients with GIST who had recurrence or metastasis after the first surgery and underwent one or more operations again from February 2003 to January 2016 at Ruijin Hospital, Shanghai Jiaotong University School of Medicine. The clinical characteristics of these patients were analyzed. Read More

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November 2018
1 Read

Adipose tissue exosomal proteomic profile reveals a role on placenta glucose metabolism in gestational diabetes mellitus.

J Clin Endocrinol Metab 2018 Dec 3. Epub 2018 Dec 3.

Exosome Biology Laboratory, Centre for Clinical Diagnostics, University of Queensland Centre for Clinical Research, Royal Brisbane and Women's Hospital, The University of Queensland, Brisbane QLD, Australia.

Context: Molecules produced by adipose tissue (AT) function as an endocrine link between maternal AT and fetal growth by regulating placental function in normal and gestational diabetes mellitus (GDM).

Objective: We hypothesised that AT-derived exosomes from women with GDM carry a specific set of proteins that influences glucose metabolism in placenta.

Design: Exosomes were isolated from omental AT-conditioned media from pregnant women with normal glucose tolerance (exo-NGT, n=65) and women with GDM (exo-GDM, n=82). Read More

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December 2018
1 Read
6.209 Impact Factor

Laparoscopic splenectomy: a new approach.

Clinics (Sao Paulo) 2018 Nov 29;73:e16536. Epub 2018 Nov 29.

Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.

Objectives: To introduce a new laparoscopic splenectomy (LS) approach.

Methods: Sixteen patients underwent LS with general anaesthesia and carbon dioxide pneumoperitoneum. The details of the surgery are as follows: 1. Read More

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November 2018
4 Reads

Re: Omental infarction: a case of a whole omental infarct.

ANZ J Surg 2018 Dec;88(12):1356

Department of Paediatric Surgery, Women's and Children's Hospital, Adelaide, South Australia, Australia.

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December 2018

[A giant sacral chordoma resection and reconstruction with a gluteal perforator flap, a case report and literature review].

Ann Chir Plast Esthet 2018 Nov 30. Epub 2018 Nov 30.

Service de chirurgie orthopédique et traumatologie, chirurgie du rachis, hôpital Bicêtre, 78, rue du Général-Leclerc, 94270 Le Kremlin-Bicêtre, France.

Background: Sacral chordomas are rare primary bone tumors and represent more than half of all primary malignant sacral tumors. Surgical resection is the only treatment with close to 50% of remission at 10 years, with or without radiotherapy. This tissue removal can be very extensive and morbid, particularly for evolved tumors. Read More

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November 2018
1 Read

Pathological response of ovarian cancer to neoadjuvant chemotherapy.

Chin Clin Oncol 2018 Dec;7(6):59

N.N. Petrov Institute of Oncology, Leningradskaya 68, St.-Petersburg 197758, Russia.

There is only a few of studies devoted to evaluation of pathologic response of ovarian cancer (OC) to neoadjuvant chemotherapy (NACT). Pathologic complete responses (pCR), which are characterized by the lack of viable tumor cells in surgical specimens, are rarely observed in ovarian carcinomas. Multiple reports demonstrate that pCR is associated with evidently improved disease outcomes. Read More

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December 2018
6 Reads

Primary omental torsion.

Authors:
Vipul D Yagnik

ANZ J Surg 2018 Nov 29. Epub 2018 Nov 29.

Department of General Surgery, Ronak Endo-Laparoscopy and General Surgical Hospital, Patan, India.

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November 2018

Endothelin-1 triggers human peritoneal mesothelial cells' proliferation via ERK1/2-Ets-1 signaling pathway and contributes to endothelial cell angiogenesis.

J Cell Biochem 2018 Nov 28. Epub 2018 Nov 28.

Department of Nephrology, Shanghai Jiao Tong University Affiliated First People's Hospital, Shanghai, PR China.

Background: Dysfunction of the peritoneum as a dialysis organ may result from progressive membrane injury on peritoneal dialysis (PD). It has been increasingly recognized that the human peritoneal mesothelial cells (HPMCs) play a key role in peritoneal membrane early injury. Recently, it has been reported that bioincompatible PD fluid with high concentrations of glucose and glucose degradation products, low pH, high osmolality, and peritonitis stimulates HPMCs to release endothelin-1 (ET-1). Read More

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November 2018
1 Read

Low proliferative potential of adipose-derived stromal cells associates with hypertrophy and inflammation in subcutaneous and omental adipose tissue of patients with type 2 diabetes mellitus.

J Diabetes Complications 2018 Nov 4. Epub 2018 Nov 4.

Endocrinology Research Centre, Moscow, Russia.

Background: Obesity and type 2 diabetes mellitus (T2DM) are among the most important morbidity factors. In this study we tested the hypothesis that low proliferative potential of adipose derived stromal cells (ADSC) associates with reduced formation of new fat depots, excess accumulation of fat in the functional adipocytes and their hypertrophy, resulting in fat inflammation and insulin resistance.

Methods: We screened two groups of obese patients with or without T2DM, matched for BMI, age, and duration of obesity to test the hypothesis that hypertrophy and decreased renewal of adipocytes may underlie transition from obesity to T2DM. Read More

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November 2018
1 Read

Role of Ultrasound-Guided Fine-Needle Aspiration Cytology of Omentum in Diagnosis of Abdominal Tuberculosis.

Surg Infect (Larchmt) 2018 Nov 27. Epub 2018 Nov 27.

2 Department of Gastroenterology, Postgraduate Institute of Medical Education and Research , Chandigarh, India .

Aim: To evaluate the efficacy of ultrasound-guided (USG) fine-needle aspiration cytology examination (FNAC) of the omentum in the diagnosis of abdominal tuberculosis (TB).

Methods: Retrospective review was conducted of data from patients who presented with clinically suspected peritoneal TB between June 2016 and April 2018. We included patients in whom imaging showed omental thickening with or without ascites. Read More

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November 2018
1 Read

EPITHELIAL-TO-MESENCHYMAL TRANSITION AND MIGRATION OF HUMAN PERITONEAL MESOTHELIAL CELLS UNDERGOING SENESCENCE.

Perit Dial Int 2018 Nov 25. Epub 2018 Nov 25.

Department of Medicine I, University Witten/Herdecke, Medical Center Cologne-Merheim, Cologne, Germany

Background: Epithelial-to-mesenchymal transition (EMT) of human peritoneal mesothelial cells (HPMCs) contributes to fibrotic thickening of the peritoneum that develops in patients on peritoneal dialysis (PD). The process is thought to be largely mediated by transforming growth factor-beta (TGF-β). As TGF-β has also been implicated in senescence of HPMCs, we have performed an exploratory study to examine if senescent HPMCs can undergo EMT. Read More

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November 2018
1 Read

Post Mortem Findings in a Young Male with Congenital Generalized Lipodystrophy, Type 4 due to CAVIN1 mutations.

J Clin Endocrinol Metab 2018 Nov 21. Epub 2018 Nov 21.

Division of Nutrition and Metabolic Diseases, Department of Internal Medicine and the Center for Human Nutrition; UT Southwestern Medical Center, Dallas, Texas, USA.

Context: Congenital generalized lipodystrophy, type 4 (CGL4) is a rare autosomal recessive disorder caused by CAVIN1 mutations. Patients with CGL4 also have myopathy and cardiomyopathy with a predisposition for sudden death due to ventricular arrhythmias. However, underlying pathology for these morbidities remains unknown. Read More

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November 2018
2 Reads

Complications associated with higher order compared to lower order cesarean sections.

J Matern Fetal Neonatal Med 2018 Nov 21:1-161. Epub 2018 Nov 21.

b West Kazakhstan State Medical University, Aktobe, Kazakhstan (WKSMU) , Aktobe , Kazakhstan.

Background: The rate of multiple cesarean sections is persistently on the rise because of cultural demands for large families, and multiple cesarean sections are an important cause of maternal morbidity and mortality.

Objectives: This study was designed to detect the complications associated with higher order compared to lower order cesarean sections.

Materials And Methods: The hospitals record of women who had a cesarean section performed after three or more previous cesarean sections, and those who had a cesarean section for the second time over 2 years reviewed. Read More

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November 2018

Patients with extensive regional lymph node involvement (pN2) following potentially curative surgery for colorectal cancer are at an increased risk for developing peritoneal metastases - a retrospective single institution study.

Colorectal Dis 2018 Nov 20. Epub 2018 Nov 20.

Dept. of Surgical Oncology, Tata Memorial Hospital, Mumbai, India.

Objectives: The goal was to determine the incidence and clinical behavior of peritoneal metastases (PM) in patients with colorectal cancer undergoing potentially curative surgery, comparing patients with extensive loco-regional lymph node involvement (pN2) with those who have serosal involvement (pT4), a known risk factor for developing PM.

Methods: A retrospective analysis of a prospectively maintained database was performed. All patients with pT4 and pN2 were included in the analysis. Read More

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November 2018
5 Reads

Laparoscopic repositioning of chronic gastric volvulus in a dog.

J S Afr Vet Assoc 2018 Nov 6;89(0):e1-e5. Epub 2018 Nov 6.

Department of Companion Animal Clinical Studies, University of Pretoria.

A 12-year-old spayed Newfoundland bitch was presented with chronic non-productive vomiting, regurgitation and coughing of six weeks' duration. On clinical examination, the dog was depressed with no other significant findings. Haematology and biochemistry investigations detected no abnormalities. Read More

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November 2018
3 Reads

An omentum-cultured 3D-printed artificial trachea: in vivo bioreactor.

Artif Cells Nanomed Biotechnol 2018 Nov 19:1-10. Epub 2018 Nov 19.

a Department of Otorhinolaryngology-Head and Neck Surgery, Chuncheon Sacred Heart Hospital, College of Medicine , Hallym University , Chuncheon , Republic of Korea.

The purpose of this study was to evaluate whether the prior implantation of a 3D-printed polycaprolactone (PCL) artificial trachea in the omentum is beneficial for revascularization of the scaffold and reduces associated complications in the reconstruction of a circumferential tracheal defect. Ten New Zealand rabbits were divided into 2 groups: (1) PCL-OC group (PCL scaffold cultured in omentum for 2 weeks before transplantation) and (2) PCL group. In the PCL-OC group, newly formed connective tissue completely covered the luminal surface of the scaffold with mild inflammation at 2 weeks postoperatively; a minor degree of stenosis was noted at 8 weeks postoperatively. Read More

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November 2018
6 Reads

Giant omental lipoma in an elderly female patient.

Med J Armed Forces India 2018 Oct 17;74(4):377-379. Epub 2017 Jul 17.

Classified Specialist (Pathology), Military Hospital Thiruvananthapuram, India.

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October 2018
1 Read

Molecular Mechanisms Regulating Organ-Specific Metastases in Epithelial Ovarian Carcinoma.

Cancers (Basel) 2018 Nov 15;10(11). Epub 2018 Nov 15.

Department of Biopharmaceutical Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA.

Epithelial ovarian carcinoma is the most predominant type of ovarian carcinoma, the deadliest gynecologic malignancy. It is typically diagnosed late when the cancer has already metastasized. Transcoelomic metastasis is the most predominant mechanism of dissemination from epithelial ovarian carcinoma, although both hematogenously and lymphogenously spread metastases also occur. Read More

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November 2018
1 Read

Yolk Sac Tumor of Stomach: Case Report and Review of Literature.

J Indian Assoc Pediatr Surg 2018 Oct-Dec;23(4):232-233

Department of Radiodiagnosis, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Gastric yolk sac tumors (YSTs) are very rare. Only seven cases of pure YST of the stomach, with a median age of 65 years, and five cases of YST combined with adenocarcinoma have been reported. We report a 3-year-old boy who presented to us with recurrent episodes of melena and anemia of 2 months' duration. Read More

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November 2018
3 Reads

Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells.

Sci Transl Med 2018 Nov;10(467)

Immunoregulation Section, National Institute on Aging, Baltimore, MD 21224, USA.

Aging in humans is associated with increased hyperglycemia and insulin resistance (collectively termed IR) and dysregulation of the immune system. However, the causative factors underlying their association remain unknown. Here, using "healthy" aged mice and macaques, we found that IR was induced by activated innate 4-1BBL B1a cells. Read More

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November 2018
8 Reads
15.843 Impact Factor

A Challenging Diagnosis of Ascites: A Case Report of Peritoneal Tuberculosis.

Case Rep Infect Dis 2018 23;2018:8136476. Epub 2018 Oct 23.

University of Florida-COM, Division of Internal Medicine, Jacksonville, FL, USA.

Approximately 2 billion people, which is about one third of the world's population, are infected with tuberculosis (TB). Around 10% of infected people will develop active TB at one point in their lifetime. We present a rare case of a 68-year-old male who presented to the emergency department with a 2-week progressive dyspnea. Read More

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October 2018
3 Reads

An atypical presentation of an ovarian lymphoma: a case report.

J Med Case Rep 2018 Nov 14;12(1):338. Epub 2018 Nov 14.

Department of Obstetrics & Gynaecology, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.

Background: Ovarian lymphoma has a varied clinical presentation and rarely presents with heavy menstrual bleeding. It may occur de novo or secondary to systemic disease and macroscopically appear as solid ovarian tumors.

Case Presentation: A 32-year-old Tamil woman presented with heavy menstrual bleeding of 4 months' duration. Read More

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November 2018
7 Reads

The antitumor effects of entinostat in ovarian cancer require adaptive immunity.

Cancer 2018 Dec 13;124(24):4657-4666. Epub 2018 Nov 13.

Division of Gynecologic Oncology, University of Alabama at Birmingham, Birmingham, Alabama.

Background: Ovarian cancer is poorly immunogenic; however, increased major histocompatibility complex class II (MHCII) expression correlates with improved immune response and prolonged survival in patients with ovarian cancer. The authors previously demonstrated that the histone deacetylase inhibitor entinostat increases MHCII expression on ovarian cancer cells. In the current study, they evaluated whether entinostat treatment and resultant MHCII expression would enhance beneficial immune responses and impair tumor growth in mice with ovarian cancer. Read More

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December 2018
6 Reads

Comparative evaluation of decellularized porcine liver matrices crosslinked with different chemical and natural crosslinking agents.

Xenotransplantation 2018 Nov 10:e12470. Epub 2018 Nov 10.

Laboratory of Pathology, Key Laboratory of Transplant Engineering and Immunology, NHFPC, West China Hospital, Sichuan University, Chengdu, China.

The natural liver extracellular matrix (ECM) achieved by decellularization holds great potential in the fields of tissue engineering and regenerative medicine. Additionally, the use of crosslinking agents on the ECM to stabilize its ultrastructure and enhance scaffold durability is gaining interest in tissue engineering. The objective of this study was to compare the scaffold properties of porcine liver ECM crosslinked with different agents (glutaraldehyde, genipin, and quercetin) to find the best strategy for producing a decellularized matrix with optimal and stable characteristics for transplantation and regeneration. Read More

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November 2018
8 Reads
2.840 Impact Factor

A Rare Presentation of Precursor B-cell Lymphoblastic Lymphoma in a Child.

Cureus 2018 Aug 31;10(8):e3238. Epub 2018 Aug 31.

Pathology, Shifa International Hospital Islamabad, Islamabad, PAK.

Precursor B-cell lymphoblastic lymphoma, a type of non-Hodgkin lymphoma, is common in children. It is mostly extranodal; skin, bone and soft tissue are more often involved. However, isolated peritoneal presentation is rare. Read More

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August 2018
6 Reads

Personalized Hydrogels for Engineering Diverse Fully Autologous Tissue Implants.

Adv Mater 2018 Nov 8:e1803895. Epub 2018 Nov 8.

School for Molecular Cell Biology and Biotechnology, Tel Aviv University, Tel Aviv, 69978, Israel.

Despite incremental improvements in the field of tissue engineering, no technology is currently available for producing completely autologous implants where both the cells and the scaffolding material are generated from the patient, and thus do not provoke an immune response that may lead to implant rejection. Here, a new approach is introduced to efficiently engineer any tissue type, which its differentiation cues are known, from one small tissue biopsy. Pieces of omental tissues are extracted from patients and, while the cells are reprogrammed to become induced pluripotent stem cells, the extracellular matrix is processed into an immunologically matching, thermoresponsive hydrogel. Read More

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November 2018
13 Reads

Effective Combination of Different Surgical Strategies for Deep Sternal Wound Infection and Mediastinitis.

Ann Thorac Cardiovasc Surg 2018 Nov 7. Epub 2018 Nov 7.

Department of Thoracic and Cardiovascular Surgery, University Hospital RWTH Aachen, Germany.

Purpose: Timing and ideal reconstructive approach in deep sternal wound infection (DSWI) and mediastinitis still remain controversially debated. We present our own combined surgical strategy of bilateral pectoralis major muscle flap (BPMMF) or omental flap (OF) transposition.

Methods: Between July 2010 and July 2016, poststernotomy patients with DSWI and mediastinitis underwent a secondary wound closure with modified BPMMF (Group A, center for disease control class (CDC)-II, n = 21; Group B, CDC-III, n = 20) or with OF (Group C, CDC-III, n = 19) following vacuum-assisted closure (VAC). Read More

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November 2018
4 Reads

Thrombotic Ringed Polytetrafluoroethylene Graft With Infection After Living-Donor Liver Transplantation.

Transplant Proc 2018 Nov 1;50(9):2606-2610. Epub 2018 May 1.

Division of Transplantation Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan; Department of Surgery, School of Medicine, National Yang-Ming University, Taipei, Taiwan. Electronic address:

Background: The safety of the living donor in living-donor liver transplantation (LDLT) is always the first priority, meanwhile, the graft-to-recipient weight ratio (GRWR) and the anatomy of the liver allograft must also not be compromised in order to warrant tranplatation success. When it comes to the allograft of the right lobe of the liver without the middle hepatic vein (R-M), the outflow and adequate drainage for the territory of middle hepatic vein (MHV) is one critical concern. Despite publications in some high-volume transplant centers on the positive results of using expanded polytetrafluoroethylene (ePTFE) grafts to substitute those of autologous veins, complications related to the ePTFE graft have not been well discussed. Read More

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November 2018
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Reducing the occurrence rate of catheter dysfunction in peritoneal dialysis: a single-center experience about CQI.

Ren Fail 2018 Nov;40(1):628-633

a Department of Nephrology , The Third Xiangya Hospital of Central South University , Changsha , China.

To reduce the occurrence rate of peritoneal dialysis (PD) catheter dysfunction caused by catheter displacement or plugging, this study screened all patients with peritoneal dialysis catheterization from 2002 to 2015 from the Third Xiangya Hospital of Central South University. There were 256 patients before continuous quality improvement (CQI) (from 2002 to 2007) and 813 patients after CQI (from 2008 to 2015). The occurrence rate of catheter dysfunction was 5. Read More

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November 2018
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