2,939 results match your criteria Oligohydramnios


Clinical outcome is associated with the Urinary Tract Dilatation Classification System grade.

Croat Med J 2020 Jul;61(3):246-251

Tanja Kersnik Levart, Department of Nephrology, Division of Pediatrics, University Medical Centre, Bohoričeva 20, 1000 Ljubljana, Slovenia,

Aim: To assess the association between the Urinary Tract Dilatation (UTD) Antenatal (A) and Postnatal (P) Classification System grade and the outcome in term newborns.

Methods: This retrospective study enrolled 166 term newborns (71% boys, 206 ureterorenal units) evaluated for unilateral or bilateral UTD in the Neonatology Department of Ljubljana University Medical Center from 2012 to 2018. Data on family history, sex, gestational age, birth weight, head circumference, Apgar score, possible oligohydramnios, indication for and age at first postnatal ultrasound, time of follow-up, and clinical outcome were collected. Read More

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Novel loss of function variants in FRAS1 AND FREM2 underlie renal agenesis in consanguineous families.

J Nephrol 2020 Jul 8. Epub 2020 Jul 8.

Department of Genetics, King Faisal Specialist Hospital and Research Centre, P. O. Box 3354, Riyadh, Saudi Arabia.

Introduction: Congenital anomalies of the kidney and urinary tract (CAKUT) are a group of abnormalities that affect structure of the kidneys or other structures of the urinary tract. The majority of CAKUT are asymptomatic and are diagnosed prenatally by ultrasound scanning or found incidentally in postnatal life. CAKUT varies in severity and may lead to life-threatening kidney failure and end-stage kidney disease. Read More

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http://dx.doi.org/10.1007/s40620-020-00795-0DOI Listing

Efficacy of an ultrasound training program for nurse midwives to assess high-risk conditions at labor triage in rural Uganda.

PLoS One 2020 30;15(6):e0235269. Epub 2020 Jun 30.

Department of Emergency Medicine, Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts, United States of America.

Many high-risk conditions of pregnancy are undetected until the time of delivery in low-income countries. We developed a point-of-care ultrasound training protocol for providers in rural Uganda to detect fetal distress or demise, malpresentation, multiple gestation, placenta previa, oligohydramnios and preterm delivery. This was a mixed-methods study to evaluate the 2-week training curriculum and trainees' ability to perform a standard scanning protocol and interpret ultrasound images. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0235269PLOS

Application of Tissue Engineering and Regenerative Medicine in Maternal-Fetal Medicine.

Adv Exp Med Biol 2020 ;1249:161-171

Department of obstetrics and gynecology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

A rapid development of ultrasonography has enabled physicians to make earlier prenatal diagnosis of various fetal congenital diseases, in maternal-fetal medicine. Due to the significant mortality and irreversible damage to fetal vital organs during pregnancy, fetal surgeries have been tried in some congenital disease including congenital diaphragmatic hernia, twin-to-twin transfusion syndrome (TTTS), myelomeningocele (MMC), and lower urinary tract obstruction. However, open fetal surgery requires laparotomy followed by hysterotomy, which can cause preterm premature rupture of membrane (pPROM), oligohydramnios, preterm delivery, dehiscence of uterine wall, and other maternal complications during pregnancy. Read More

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http://dx.doi.org/10.1007/978-981-15-3258-0_11DOI Listing
January 2020

Prenatal exposure to isolated amniotic fluid disorders and the risk for long-term endocrine morbidity of the offspring.

Arch Gynecol Obstet 2020 Jun 29. Epub 2020 Jun 29.

Department of Obstetrics and Gynecology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, POB 151, 84101, Beer-Sheva, Israel.

Background: Amniotic fluid abnormalities may be associated with adverse perinatal outcomes, some of which are endocrine related.

Objective: To evaluate whether in utero exposure to amniotic fluid abnormalities is associated with long-term endocrine morbidity in the offspring.

Study Design: In this cohort study, the incidence of long-term endocrine disorders was compared between singletons exposed and non-exposed to oligohydramnios or polyhydramnios. Read More

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http://dx.doi.org/10.1007/s00404-020-05674-4DOI Listing
June 2020
1.279 Impact Factor

Pregnancy and delivery in women with a high risk of infection in pregnancy.

J Matern Fetal Neonatal Med 2020 Jun 23:1-6. Epub 2020 Jun 23.

Federal State Funded Educational Institution for Higher Education Omsk State Medical University, Ministry of Public Health, Russian Federation.

Pregnant women with chronic genital and non-genital infections are at a high risk of infections complication during pregnancy and the postpartum period. Preterm birth is one of the leading causes of obstetric and neonatal complications and occurs in one in nine women. Forty per cent of preterm births are considered to be caused by the abnormal vaginal microbiome, and there is currently no consensus on the contribution of combined bacterial and viral infections. Read More

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http://dx.doi.org/10.1080/14767058.2020.1781810DOI Listing

Prevention of perinatal complications in pregnant women with chronic papillomavirus infection.

Pol Merkur Lekarski 2020 Jun;48(285):157-161

I. Horbachevsky Ternopil National Medical University, Ternopil, Ukraine.

Social trends, a new style of modern young woman, which includes the polygamy of sexual relationships, increases the incidence and probability of infection caused by sexually transmitted pathogens, including the human papillomavirus. In women entered into motherhood with chronic papillomavirus carrier, pregnancy is accompanied with an increase in obstetrics and perinatal complications. The inability to use antiviral therapy due to its embryo- and fetotoxic effects requires searching for safe agents for timely and effective preconceptional and prenatal preparation for the fetal infection prevention. Read More

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Perinatal Outcome of Twin Pregnancies Complicated by Rupture of Membranes at 13-20 Weeks: Is Selective Termination an Appropriate Management Option?

Ultraschall Med 2020 Jun 15. Epub 2020 Jun 15.

ObGyn, Chaim Sheba Medical Center, Tel Hashomer, Israel.

Objective:  To evaluate the outcome of twin pregnancies that were complicated by rupture of membranes at 13-20 weeks of gestation and were managed by expectant management or by selective termination.

Methods:  A retrospective cohort study of all bichorionic twin pregnancies that were referred to three fetal medicine units between 2001 and 2016, due to rupture of membranes of one sac at 13-20 weeks of gestation. Women without clinical signs of infection who opted for expectant management or selective termination were included. Read More

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http://dx.doi.org/10.1055/a-1176-0919DOI Listing

Aquaporin 1 affects pregnancy outcome and regulates aquaporin 8 and 9 expressions in the placenta.

Cell Tissue Res 2020 Jun 15. Epub 2020 Jun 15.

Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Wenzhou Medical University, No. 109 Xueyuan Xi Road Wenzhou, Zhejiang, 325027, China.

To explore the effects of aquaporin (AQP) 1 on pregnancy outcome and the association between expression of AQP1 and other AQPs in the placenta and foetal membranes, the rate of copulatory plugs and pregnancy, amniotic fluid (AF) volume, osmolality and composition were determined in AQP1-knockout (AQP1) mice at different gestational days (GD). The expression and location of AQP1 and other AQPs in the placenta and foetal membranes of AQP1 mice, AQP1-siRNA transfected WISH cells and oligohydramnios patients were also detected. Compared to control mice, AQP1 mice exhibited reduced copulation plug and successful pregnancy rates, but these effects were accompanied by a larger AF volume and lower AF osmolality at late gestation. Read More

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http://dx.doi.org/10.1007/s00441-020-03221-wDOI Listing

Perinatal and infant outcome in prenatally diagnosed hyperechogenic kidneys.

Ultrasound Obstet Gynecol 2020 Jun 12. Epub 2020 Jun 12.

Nephro-Urology Group, Developmental Biology and Cancer Programme, UCL Great Ormond Street Institute of Child Health.

Objective: Hyperechogenic kidneys are a relatively rare antenatal finding, but they generate significant parental anxiety due to uncertain prognosis. We report perinatal and infant outcomes in a large cohort of fetuses with antenatal hyperechogenic kidneys.

Methods: All cases diagnosed prenatally between 2002 and 2017 with hyperechogenic kidneys were assessed in a large tertiary fetal medicine unit. Read More

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http://dx.doi.org/10.1002/uog.22121DOI Listing

Fetal left ventricular modified myocardial performance index and renal artery pulsatility index in pregnancies with isolated oligohydramnios before 37 weeks of gestation.

J Turk Ger Gynecol Assoc 2020 06 10. Epub 2020 Jun 10.

İstanbul University-Cerrahpaşa, Cerrahpaşa Faculty of Medicine, Department of Obstetrics and Gynecology, Division of Perinatal Medicine, İstanbul, Turkey.

Objective: We aimed to evaluate fetal left modified myocardial performance index and renal artery Doppler parameter in fetuses with isolated oligohydramnios and normal amount of amniotic fluid.

Material And Methods: In a prospective cohort study, 25 pregnancies with isolated oligohydramnios and 25 healthy gestational age matched controls between 24+0 to 36+6 weeks of gestation were recruited. Primary outcome was to compare left modified myocardial performance index and mean fetal renal artery PI and secondary outcome was to compare adverse perinatal outcomes between the groups. Read More

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http://dx.doi.org/10.4274/jtgga.galenos.2020.2019.0160DOI Listing

Contemporary Outcomes of Patients with Isolated Bilateral Renal Agenesis with and without Fetal Intervention.

Fetal Diagn Ther 2020 Jun 9:1-7. Epub 2020 Jun 9.

Cincinnati Fetal Center, Cincinnati, Ohio, USA.

Introduction: Bilateral renal agenesis (BRA) is a lethal diagnosis, specifically meaning that natural survival beyond birth is not expected secondary to pulmonary hypoplasia. Limited contemporary data are available about intervention and the impact of restoring amniotic fluid volume in relation to the risk for lethal pulmonary hypoplasia and other factors that might influence survival in cases of fetal BRA.

Objective: We report the largest series of patients undergoing fetal intervention and postnatal care for BRA at a single comprehensive fetal center. Read More

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http://dx.doi.org/10.1159/000507700DOI Listing

Tübingen hip flexion splints for developmental dysplasia of the hip in infants aged 0-6 months.

BMC Pediatr 2020 Jun 5;20(1):280. Epub 2020 Jun 5.

Department of Orthopedics, Kunming Children's Hospital, 288 Qianxing Road, Xishan District, Kunming, 650034, Yunnan, China.

Background: Developmental dysplasia of the hip (DDH) is a common disorder in infants. The present study aimed to evaluate the efficacy and safety of the Tübingen hip flexion splints in treating DDH in infants aged 0-6 months.

Methods: This is a retrospective study analyzing 259 hips in 195 infants with DDH of Graf type IIc or worse classifications treated between January 2015 and December 2017. Read More

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http://dx.doi.org/10.1186/s12887-020-02171-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275443PMC
June 2020
1.918 Impact Factor

Effect of coffee consumption on fetal renal artery blood flow and amniotic fluid volume in third trimester of pregnancy.

Pak J Med Sci 2020 May-Jun;36(4):735-739

Yusuf Madendag, MD. Department of Obstetrics and Gynecology, Erciyes University, Faculty of Medicine, Kayseri, Turkey.

Objective: Coffee is frequently (one or two cups/day) consumed throughout pregnancy. Although there are a few studies evaluating caffeine effects on pregnancy; however, a diuretic effect of caffeine on fetal kidneys has not been reported. Therefore, after drinking coffee whether changing of amniotic fluid index (AFI) and fetal renal artery blood flow (FRABF, RI, Resistive index; PI, Pulsatility index) were evaluated in this study. Read More

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http://dx.doi.org/10.12669/pjms.36.4.1690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7260913PMC

Decision-to-delivery interval of emergency cesarean section in Uganda: a retrospective cohort study.

BMC Pregnancy Childbirth 2020 May 27;20(1):324. Epub 2020 May 27.

School of Clinical Medicine, University of Cambridge, NIHR Cambridge Comprehensive Biomedical Research Centre, Cambridge, CB2 0SW, UK.

Background: In many low and medium human development index countries, the rate of maternal and neonatal morbidity and mortality is high. One factor which may influence this is the decision-to-delivery interval of emergency cesarean section. We aimed to investigate the maternal risk factors, indications and decision-to-delivery interval of emergency cesarean section in a large, under-resourced obstetric setting in Uganda. Read More

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http://dx.doi.org/10.1186/s12884-020-03010-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251662PMC

Identification of a 6-month-old baby with a combination of WAGR and Potocki-Shaffer contiguous deletion syndromes by SNP array testing.

Hereditas 2020 May 23;157(1):23. Epub 2020 May 23.

Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, 100191, China.

WAGR 11p13 deletion syndrome is associated with abnormalities including (W) ilms tumor, (A) niridia, (G) enitourinary abnormalities, and growth and mental (R) etardation (WAGR). Potocki-Schaffer syndrome is a contiguous gene syndrome associated with deletions in 11p11.2, principal features of which are multiple exostoses, parietal foramina development delay, mental retardation, and facial dysmorphism. Read More

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http://dx.doi.org/10.1186/s41065-020-00132-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245943PMC

The effect of fetal weight on the accuracy of sonographic weight estimation among women with diabetes.

J Matern Fetal Neonatal Med 2020 May 22:1-7. Epub 2020 May 22.

Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

The assessment of sonographic estimated fetal weight (EFW) enables identification of fetuses in the extremes of weight, thus aiding in the planning and management of peripartum care. There are conflicting reports regarding the accuracy of EFW in diabetic mothers. We aimed to study the factors associated with the accuracy of EFW at term, specifically the role of gestational and pre-gestational diabetes in this setting. Read More

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http://dx.doi.org/10.1080/14767058.2020.1769592DOI Listing

Estimated fetal weight accuracy in pregnancies with preterm prelabor rupture of membranes by the Hadlock method.

J Matern Fetal Neonatal Med 2020 May 22:1-5. Epub 2020 May 22.

Department of Obstetrics & Gynecology, University of Tennessee Health Science Center, Memphis, TN, USA.

We aimed to assess the accuracy of the estimated fetal weight (EFW) to predict the birthweigth (BW) in pregnancies complicated by PPROM. This study was a secondary analysis of a prospective cohort of pregnancies with PPROM. We included singleton pregnancies from 23 to 36 + 6 weeks, mothers from 13 to 46 years of age, and those with an EFW within two weeks of delivery. Read More

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http://dx.doi.org/10.1080/14767058.2020.1769593DOI Listing

False diagnosis of small for gestational age and macrosomia - clinical and sonographic predictors.

J Matern Fetal Neonatal Med 2020 May 19:1-7. Epub 2020 May 19.

Department of Obstetrics and Gynecology, Hillel Yaffe Medical Center, Hadera, Israel.

To investigate clinical and sonographic features associated with sonographic accuracy for the prediction of small for gestational age (SGA) and macrosomia at birth. The database of a tertiary medical center was retrospectively searched for women who gave birth at term to a singleton healthy neonate in 2007-2014 and underwent sonographic estimated fetal weight (sEFW) evaluation within 3 d before delivery. Fetal growth restriction (FGR) and SGA were defined as sEFW or birth weight <10th percentile for gestational age; macrosomia was defined as birth weight >4000 grams. Read More

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http://dx.doi.org/10.1080/14767058.2020.1762559DOI Listing

Histologic chorioamnionitis concomitant placental abruption and its effects on pregnancy outcome.

Placenta 2020 05 27;94:39-43. Epub 2020 Mar 27.

Department of Obstetrics & Gynecology, The Edith Wolfson Medical Center, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Holon, Israel.

Introduction: Two possible causative pathways have been suggested to participate in the development of placental abruption (PA), an acute inflammatory pathway and placental vascular derived, a chronic pathway. We aimed to study the impact of the inflammatory pathway on maternal and neonatal outcome.

Methods: The computerized medical files and placental reports of all pregnancies diagnosed with PA, between 11/2008-1/2019, at 24-42 weeks, were reviewed. Read More

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http://dx.doi.org/10.1016/j.placenta.2020.03.012DOI Listing

Marginal placental cord insertion: the need for follow up?

J Matern Fetal Neonatal Med 2020 May 13:1-7. Epub 2020 May 13.

Department of Obstetrics, Gynecology & Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA.

The objectives of this study were (1) to estimate the association between marginal placental cord insertion (PCI) and small for gestational age (SGA) and other adverse perinatal outcomes and (2) to determine if pregnancy-associated plasma protein A (PAPP-A) levels was altered in these patients. It was a retrospective cohort study of singleton pregnancies undergoing ultrasound between 2016 and 2018. Marginal PCI was defined as a distance of ≤2 cm from placental edge to PCI site, visualized in both sagittal and transverse planes, and diagnosed between 16 and 32 weeks. Read More

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http://dx.doi.org/10.1080/14767058.2020.1763297DOI Listing

Diagnosis of Persistent Cloaca by Ultrasonography and MRI: A Case Report.

Am J Case Rep 2020 May 8;21:e921576. Epub 2020 May 8.

Shizuoka Children's Hospital, Perinatal Medical Center, Shizuoka City, Shizuoka, Japan.

BACKGROUND Persistent cloacal malformations are rare anomalies that are anorectal malformations occurring in females. In cases of persistent cloaca, prenatal ultrasonography shows fetal ascites, cystic tumor in the abdomen, oligohydramnios, and hydronephrosis. There are various types of persistent cloaca, and symptoms vary. Read More

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http://dx.doi.org/10.12659/AJCR.921576DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237796PMC

Revisiting the management of term breech presentation: a proposal for overcoming some of the controversies.

BMC Pregnancy Childbirth 2020 May 3;20(1):263. Epub 2020 May 3.

Department of Obstetrics and Gynecology, Assistance Publique - Hôpitaux de Paris, Hôpital Jean Verdier, Bondy, France.

Background: The debate surrounding the management of term breech presentation has excessively focused on the mode of delivery. Indeed, a steady decline in the rate of vaginal breech delivery has been observed over the last three decades, and the soundness of the vaginal route was seriously challenged at the beginning of the 2000s. However, associations between adverse perinatal outcomes and antenatal risk factors have been observed in foetuses that remain in the breech presentation in late gestation, confirming older data and raising the question of the role of these antenatal risk factors in adverse perinatal outcomes. Read More

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http://dx.doi.org/10.1186/s12884-020-2831-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7196223PMC

Thanatophoric Skeletal Dysplasia: A Case Report.

JNMA J Nepal Med Assoc 2020 Mar;58(223):185-187

Department of Pediatrics, Patan Academy of Health Sciences, School of Medicine Patan Hospital, Lalitpur, Nepal.

Thanatophoric skeletal dysplasiais the most lethal, rare, sporadic birth defect due to de novo mutation in the fibroblast growth factor receptor-3. Clinically this is characterized by shortening of the limbs (micromelia), small conical thorax, flat vertebral bodies and macrocephaly at birth. We encountered a similar case with ultrasonographic findings suggestive of Thanatophoric Skeletal Dysplasia which resulted in the death of the baby within an hour of birth. Read More

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Panniculitis as an Initial Presentation of Dermatomyositis: A Case Report.

JNMA J Nepal Med Assoc 2020 Mar;58(223):181-184

Department of Pathology, National Academy of Medical Sciences, Kathmandu, Nepal.

Dermatomyositis is an idiopathic muscle disease characterized by proximal muscle weakness, raised muscle enzymes, characteristic changes in electromyography and typical skin rash and biopsy findings. Dermatological features like Gottron's sign and papules are considered as pathognomonic for dermatomyositis. Panniculitis is one of the rare findings in dermatomyositis. Read More

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Rare manifestations of Potter Sequence: A Case Report.

JNMA J Nepal Med Assoc 2020 Mar;58(223):178-180

Neonatal Unit, Department of Pediatrics, Kathmandu Medical College Teaching Hospital, Sinamangal, Kathmandu, Nepal.

Potter sequence is a rare congenital malformation that primarily affects male fetuses and is characterized by pulmonary hypoplasia, skeletal malformation, and kidney abnormalities. The pressure of the uterine wall due to oligohydramnios leads to an unusual facial appearance, abnormal limbsor limbs in abnormal positions or contractures. The fetus generally dies soon after birth due to respiratory insufficiency. Read More

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[Ultrasonographic manifestation and genetic analysis of a fetus with nephronophthisis type 2].

Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2020 May;37(5):559-562

Center of Genetics and Prenatal Diagnosis, Department of Obstetrics and Gynecology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.

Objective: To carry out genetic analysis for a family with a fetus manifesting bilateral polycystic renal dysplasia and oligohydramnios at 16 gestational week and a previous history for fetal renal anomaly.

Methods: Ultrasound scan was carried out to detect the morphological changes. Following genetic counselling, the parents had decided to terminate the pregnancy. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1003-9406.2020.05.016DOI Listing

Amniotic fluid index curves in the obese gravida.

J Neonatal Perinatal Med 2020 Apr 18. Epub 2020 Apr 18.

Department of Obstetrics and Gynecology, Maternal Fetal Medicine, Augusta University Medical Center at Medical College of Georgia.

Objective: To determine whether amniotic fluid volume as measured by amniotic fluid index (AFI) is influenced by maternal pre-gestational obesity as measured by body mass index (BMI).

Methods: This was a retrospective cohort study of pregnant women between 20 and 43 weeks gestation receiving ultrasounds with AFI measurements at Augusta University Medical Center between 2003 and 2017. A subset of 500 charts that met inclusion and exclusion criteria were reviewed to obtain maternal clinical data. Read More

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http://dx.doi.org/10.3233/NPM-190290DOI Listing

The changing situation about maternal age, risk factors and pregnancy outcomes after the two-child policy: a retrospective cohort study.

Ann Palliat Med 2020 May 16;9(3):824-834. Epub 2020 Apr 16.

Department of Gynaecology and Obstetrics, Zhujiang Hospital of Southern Medical University, The Second School of Clinical Medicine, Southern Medical University, Guangzhou 510515, China.

Background: To evaluate the relationship between gestational age, risk factors, pregnancy outcomes, and the causes and trends of the changes in the incidence of pregnancy in different years after the two-child policy.

Methods: The study enrolled all of the childbirth women (n=7,016) from January 1st, 2015 to December 31th, 2017 in the Zhujiang Hospital. According to the age of all childbirth women, they were divided into four groups: ≤24, 25-29, 30-34 and ≥35 years old. Read More

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http://dx.doi.org/10.21037/apm.2020.04.27DOI Listing

Postnatal serum creatinine is elevated in preterm infants with PPROM-induced anhydramnios.

Pediatr Neonatol 2020 Mar 24. Epub 2020 Mar 24.

Department of Pediatrics I, Neonatology, Pediatric Intensive Care, Pediatric Neurology, University Hospital Essen, University Duisburg-Essen, Hufelandstr. 55, 45147 Essen, Germany; Division of Neonatology and Pediatric Intensive Care, Department of Pediatrics, University Hospital Erlangen, University of Erlangen-Nürnberg, Loschgestr. 15, 91054 Erlangen, Germany. Electronic address:

Background: The reason for increased serum creatinine levels in preterm infants often remains unclear. We aimed to determine whether postnatal serum creatinine in preterm infants correlates with intake of amniotic fluid, represented by the amount of amniotic fluid after preterm premature rupture of membranes (PPROM).

Methods: 74 preterm infants with PPROM > 48 h duration were retrospectively studied. Read More

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http://dx.doi.org/10.1016/j.pedneo.2020.03.010DOI Listing

The effect of maternal position on fetal middle cerebral artery Doppler indices and its association with adverse perinatal outcomes: a pilot study.

J Perinat Med 2020 Mar 30. Epub 2020 Mar 30.

Department of Obstetrics and Gynecology, Maimonides Medical Center, Brooklyn NY 11219, USA.

Objective The aim of this study was to compare position-related changes in fetal middle cerebral artery (MCA) Doppler pulsatility indices (PI). Methods A prospective study of 41 women with conditions associated with placental-pathology (chronic hypertension, pregestational diabetes, and abnormal analytes) and 34 women without those conditions was carried out. Fetal MCA Doppler velocity flow waveforms were obtained in maternal supine and left lateral decubitus positions. Read More

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http://dx.doi.org/10.1515/jpm-2019-0399DOI Listing
March 2020
1.425 Impact Factor

Neonatal outcome comparisons between preterm infants with or without early pulmonary hypertension following prolonged preterm premature rupture of membranes before 25 gestational weeks in Korean Neonatal Network.

J Matern Fetal Neonatal Med 2020 May 6:1-9. Epub 2020 May 6.

Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.

To determine the outcomes of very low birth weight infants (VLBWIs) following maternal mid-trimester prolonged preterm premature rupture of membranes (PPROM) and subsequent early pulmonary hypertension (PH). Prospective cohort study. A nationwide web-based registry of VLBWIs from 67 neonatal intensive care units. Read More

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http://dx.doi.org/10.1080/14767058.2020.1749590DOI Listing

Neonatal outcomes following previable prelabour rupture of membranes before 23 weeks of gestation- a retrospective cohort study.

J Neonatal Perinatal Med 2020 Mar 21. Epub 2020 Mar 21.

Women and Infants Research Foundation, King Edward Memorial Hospital for Women, Perth, Australia.

Objective: To compare outcomes of hospitalized preterm infants following previable prelabour rupture of membranes (PPROM) at≤23 weeks of gestation.

Methods: Retrospective cohort study of preterm infants admitted for intensive care, between January 2006 and December 2016 following PPROM, was conducted. Short term clinical outcomes included severity of respiratory morbidity, length of hospital stay and mortality. Read More

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http://dx.doi.org/10.3233/NPM-190366DOI Listing

Adverse perinatal outcomes in 665,244 term and post-term deliveries-a Norwegian population-based study.

Eur J Obstet Gynecol Reprod Biol 2020 Apr 17;247:212-218. Epub 2020 Feb 17.

Department of Obstetrics, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Norway.

Objective: To assess the prevalence and risk of adverse perinatal outcomes in early-term (37-38 weeks), full-term (39-40 weeks), late-term (41-41 weeks), and post-term (>42 weeks) deliveries with spontaneous labor onset.

Study Design: A population-based cohort with data from the Medical Birth Registry Norway (MBRN) and Statistics Norway (SSB) was conducted. The study population consisted of 665,244 women with cephalic singleton live births at term or post-term with spontaneous labor onset during the period of 1999-2014 in Norway. Read More

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http://dx.doi.org/10.1016/j.ejogrb.2020.02.028DOI Listing

Discordance for Potter's Syndrome in a Dichorionic Diamniotic Twin Pregnancy-An Unusual Case Report.

Medicina (Kaunas) 2020 Mar 4;56(3). Epub 2020 Mar 4.

Department of Gynecologic Oncology, Medical University Pleven, 5800 Pleven, Bulgaria.

Introduction: Potter's syndrome, also known as Potter's sequence, is an uncommon and fatal disorder. Potter's sequence in a multiple pregnancy is uncommon, and its frequency remains unknown. Worldwide in a diamniotic twin pregnancy, there are only a few cases described. Read More

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http://dx.doi.org/10.3390/medicina56030109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7143793PMC

Atrial septal aneurysm in pregnancy: echocardiography and obstetric outcomes.

J Perinat Med 2020 Mar 5. Epub 2020 Mar 5.

Obstetry and Gynecology, Etlik Zubeyde Hanim Women's Health Training and Research Hospital, Ankara, Turkey.

Background Atrial septal aneurysm (ASA) is an uncommon cardiac anomaly that increases maternal morbidity during pregnancy. ASA is related to atrial arrhythmia thromboembolism and it may accompany congenital anomalies such as an atrial septal defect (ASD) or patent foramen ovale (PFO). There are no studies examining pregnancy outcomes in pregnant women with ASA. Read More

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http://dx.doi.org/10.1515/jpm-2019-0351DOI Listing

The impact of residual oligohydramnios following preterm premature rupture of membranes on adverse pregnancy outcomes: a meta-analysis.

Am J Obstet Gynecol 2020 06 25;222(6):628-630. Epub 2020 Feb 25.

1(st) Department of Obstetrics and Gynecology, Attikon Hospital, National and Kapodistrian University of Athens, Athens, Greece.

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http://dx.doi.org/10.1016/j.ajog.2020.02.022DOI Listing

Altered proteomics profile in the amnion of patients with oligohydramnios.

Physiol Rep 2020 02;8(4):e14381

Department of Obstetrics and Gynecology, Center for Developmental Health, Oregon Health and Sciences University, Portland, OR, USA.

In pregnancy, idiopathic oligohydramnios is an obstetrical complication that compromises maternal health with poor perinatal outcome. Effective therapeutic treatment of this condition has been hampered by the unknown etiology and lack of understanding of cellular and molecular mechanisms that underlie idiopathic oligohydramnios. Amniotic fluid volume (AFV) is determined by intramembranous (IM) transport of amniotic fluid across the amnion and this pathway is regulated to maintain AFV within the normal range. Read More

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http://dx.doi.org/10.14814/phy2.14381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7048322PMC
February 2020

Maternal and Neonatal Outcomes among Obese Pregnant Women in King Abdulaziz University Hospital: A Retrospective Single-Center Medical Record Review.

Med Arch 2019 Dec;73(6):425-432

Department of Obstetrics and Gynecology, King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia.

Intoruction: Pregnancy results in different physiological changes to the pregnant body resulting in weight gain. This added weight can result in poor pregnancy outcomes in obese women.

Aim: To assess the adverse maternal and neonatal outcomes among obese pregnant women. Read More

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http://dx.doi.org/10.5455/medarh.2019.73.425-432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007626PMC
December 2019

Fetal lower urinary tract obstruction: What should we tell the prospective parents?

Prenat Diagn 2020 May 26;40(6):661-668. Epub 2020 Feb 26.

Department of Obstetrics and Gynecology, Mayo Clinic College of Medicine, Rochester, Minnesota.

Fetal lower urinary tract obstruction (LUTO), which often results in marked perinatal morbidity and mortality, is caused by a heterogeneous group of anatomical defects that lead to blockage of the urethra. The classic prenatal presentation of LUTO includes megacystis with hydronephrosis. While mild forms of the disease can be associated with favorable outcomes, more severe disease commonly leads to dysplastic changes in the fetal kidneys, and ultimately oligohydramnios, which can result in secondary pulmonary hypoplasia and renal failure at birth. Read More

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http://dx.doi.org/10.1002/pd.5669DOI Listing

The association between isolated oligohydramnios at term and placental pathology in correlation with pregnancy outcomes.

Placenta 2020 01 4;90:37-41. Epub 2019 Dec 4.

Department of Obstetrics & Gynecology, The Edith Wolfson Medical Center, Holon, Israel and Sackler School of Medicine, Israel; Tel-Aviv University, Israel.

Introduction: Isolated term oligohydramnios (ITO) is an obstetrical complication of which the etiology, management, and clinical importance are controversial. In attempt to deepen our understanding, we aimed to study placental pathology and pregnancy outcomes in pregnancies complicated by ITO.

Materials And Methods: - Maternal demographics, neonatal outcomes, and placental histopathology reports of all pregnancies complicated by ITO at 37 to 41 weeks were reviewed. Read More

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http://dx.doi.org/10.1016/j.placenta.2019.12.004DOI Listing
January 2020

Secondary maternal-fetal consequences to electrical injury: A literature review.

Taiwan J Obstet Gynecol 2020 Jan;59(1):1-7

Fundación Cardiovascular de Colombia, Colombia. Electronic address:

Electrical injuries can occur in pregnant women but currently their incidence is not completely known. Notwithstanding, those represent clinical important events such maternal and fetal death, which can be avoided if properly managed. The objective of this paper is to describe the results of electrical injury (high and low voltage), in pregnant women in scientific reports. Read More

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http://dx.doi.org/10.1016/j.tjog.2019.11.001DOI Listing
January 2020

Oligohydramnios: a prospective study of fetal, neonatal and maternal outcomes in low-middle income countries.

Reprod Health 2020 Jan 30;17(1):19. Epub 2020 Jan 30.

Department of Obstetrics/Gynecology, Columbia University, New York, NY, USA.

Background: Oligohydramnios is a condition of abnormally low amniotic fluid volume that has been associated with poor pregnancy outcomes. To date, the prevalence of this condition and its outcomes has not been well described in low and low-middle income countries (LMIC) where ultrasound use to diagnose this condition in pregnancy is limited. As part of a prospective trial of ultrasound at antenatal care in LMICs, we sought to evaluate the incidence of and the adverse maternal, fetal and neonatal outcomes associated with oligohydramnios. Read More

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http://dx.doi.org/10.1186/s12978-020-0854-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6993413PMC
January 2020
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Reproductive health issues in female patients with beta-thalassaemia major: a narrative literature review.

J Obstet Gynaecol 2020 Jan 30:1-10. Epub 2020 Jan 30.

Department of Midwifery and Reproductive Health, Nursing and Midwifery School, Tehran University of Medical Sciences, Tehran, Iran.

β-thalassaemia major (BTM) has a high prevalence worldwide and is associated with considerable morbidity and mortality. The aim of this review is to provide an illustrative overview of the reproductive health and pregnancy related issues in females with β-thalassaemia. A literature search was performed in four international databases (1980-2018) to identify the potentially relevant articles. Read More

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http://dx.doi.org/10.1080/01443615.2019.1692802DOI Listing
January 2020

Child outcomes after amnioinfusion compared with no intervention in women with second-trimester rupture of membranes: a long-term follow-up study of the PROMEXIL-III trial.

BJOG 2020 Jan 27. Epub 2020 Jan 27.

Department of Obstetrics and Gynaecology, Academic Medical Centre (AMC), Amsterdam, The Netherlands.

Objective: To assess the effect of transabdominal amnioinfusion or no intervention on long-term outcomes in children born after second-trimester prelabour rupture of the membranes (PROM between 16 -24  weeks) and oligohydramnios.

Population: Follow up of infants of women who participated in the randomised controlled trial: PPROMEXIL-III (NTR3492).

Methods: Surviving infants were invited for neurodevelopmental assessment up to 5 years of corrected age using a Bayley Scales of Infant and Toddler Development or a Wechsler Preschool and Primary Scale of Intelligence. Read More

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http://dx.doi.org/10.1111/1471-0528.16115DOI Listing
January 2020

Perinatal features of Prader-Willi syndrome: a Chinese cohort of 134 patients.

Orphanet J Rare Dis 2020 Jan 21;15(1):24. Epub 2020 Jan 21.

Department of Endocrinology, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, 3333 Binsheng Rd, Hangzhou 310052, China.

Background: Prader-Willi syndrome (PWS) is a rare and complex genetic disorder caused by lacking expression of imprinted genes on the paternally derived chromosome 15q11-q13 region. This study aimed to characterize the perinatal features of 134 Chinese individuals with PWS.

Methods: This study included the patients of a PWS registry in China. Read More

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http://dx.doi.org/10.1186/s13023-020-1306-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6975078PMC
January 2020

A Case of Type I Sirenomelia Complicated by Severe Oligohydramnios in the First Trimester.

Case Rep Obstet Gynecol 2019 26;2019:4564260. Epub 2019 Dec 26.

Department of Obstetrics and Gynecology, Sakakibara Heart Institute, Fuchu, Tokyo, Japan.

Sirenomelia is a very rare congenital anomaly. Type I is the mildest type, and the long bone structures are all normally present with only soft tissue fusion. We experienced a case of type I sirenomelia complicated by severe oligohydramnios. Read More

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http://dx.doi.org/10.1155/2019/4564260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949666PMC
December 2019

Understanding Factors Leading to Primary Cesarean Section and Vaginal Birth After Cesarean Delivery in the Friuli-Venezia Giulia Region (North-Eastern Italy), 2005-2015.

Sci Rep 2020 01 15;10(1):380. Epub 2020 Jan 15.

Institute for Maternal & Child Health, IRCCS "Burlo Garofolo", Trieste, Italy.

Although there is no evidence that elevated rates of cesarean sections (CS) translate into reduced maternal/child perinatal morbidity or mortality, CS have been increasingly overused almost everywhere, both in high and low-income countries. The primary cesarean section (PCS) has become a major driver of the overall CS (OCS) rate, since it carries intrinsic risk of repeat CS (RCS) in future pregnancies. In our study we examined patterns of PCS, pl compared with planned TOLAC anned PCS (PPCS), vaginal birth after 1 previous CS (VBAC-1) and associated factors in Friuli Venezia Giulia (FVG), a region of North-Eastern Italy, collecting data from its 11 maternity centres (coded from A to K) during 2005-2015. Read More

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http://dx.doi.org/10.1038/s41598-019-57037-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6962159PMC
January 2020