254 results match your criteria Ocular Manifestations of HIV


Clinical Profile and Visual Outcomes of Ocular Syphilis: A Five-year Review in Hospital Universiti Sains, Malaysia.

Cureus 2019 Feb 5;11(2):e4015. Epub 2019 Feb 5.

Ophthalmology, Universiti Sains Malaysia, Kota Bharu, MYS.

Introduction Ocular syphilis is a sight-threatening condition. It can occur at any stage of syphilis infection, which present either with acute inflammation during the primary, secondary, and early latent stages or with chronic inflammation during tertiary infection, affecting virtually every ocular structure. This study was to report on the clinical presentation of ocular syphilis that presented to eye clinic Hospital Universiti Sains Malaysia. Read More

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http://dx.doi.org/10.7759/cureus.4015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453624PMC
February 2019

[Ocular Syphilis May Lead to Persistent Visual Dysfunction].

Klin Monbl Augenheilkd 2019 Apr 18;236(4):516-522. Epub 2019 Apr 18.

Augenklinik, UniversitätsSpital Zürich, Universität Zürich, Schweiz.

Purpose: The spectrum of intraocular and systemic findings in patients with ocular syphilis is described. Persistent visual dysfunction and structural abnormality, in spite of targeted antibiotic therapy, were identified and analysed.

Methods: Patients with ocular syphilis who were treated at University Hospital Zurich (USZ) between 2010 and 2018 were included in this study. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0854-3421
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http://dx.doi.org/10.1055/a-0854-3421DOI Listing
April 2019
1 Read

[The ocular manifestations of human immunodeficiency virus and syphilis coinfection].

Zhonghua Yan Ke Za Zhi 2019 Apr;55(4):267-272

Department of Ophthalmology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.

To investigate the ocular manifestations of human immunodeficiency virus (HIV) and syphilis coinfection. A retrospective analysis of the ocular manifestations was carried out in 27 patients (54 eyes) diagnosed as syphilis and HIV coinfection by the Department of Infectious Medicine in Peking Union Medical College Hospital during the years of 2006-2017. The research included 26 males and 1 female, aging from 24 to 76 years old, with a mean age of 40. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2019.04.008DOI Listing
April 2019
2 Reads

Presentation of Ocular Syphilis in a HIV-Positive Patient with False-Negative Serologic Screening.

Case Rep Infect Dis 2019 3;2019:8191724. Epub 2019 Feb 3.

Department of Ophthalmology, University of Arizona College of Medicine, Tucson, AZ, USA.

Purpose: The ocular sequelae of syphilis are devastating and may cause blindness. The ambiguous nature of its ocular manifestations makes syphilis difficult to detect. Though uncommon, the rise of syphilis in the United States requires a renewed understanding of its ophthalmic presentation to prevent devastating outcomes. Read More

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http://dx.doi.org/10.1155/2019/8191724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377954PMC
February 2019
1 Read

The great imitator on the rise: ocular and optic nerve manifestations in patients with newly diagnosed syphilis.

Acta Ophthalmol 2018 Oct 17. Epub 2018 Oct 17.

Division of Ophthalmology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Purpose: Ocular manifestations of syphilis have been reported in 2-10% of systemic infection. The purpose of this study was to report the incidence of ocular syphilis and various ocular manifestations, particularly optic nerve involvement, in newly diagnosed cases.

Methods: This was a retrospective study. Read More

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http://dx.doi.org/10.1111/aos.13963DOI Listing
October 2018
4 Reads

Ocular manifestations of cytomegalovirus in immunocompetent hosts.

Curr Opin Ophthalmol 2018 Nov;29(6):535-542

Francis I. Proctor Foundation, Department of Ophthalmology, University of California, San Francisco, USA.

Purpose Of Review: This review highlights recent studies that have increasingly implicated cytomegalovirus (CMV) as a significant cause of keratouveitis and retinitis in immunocompetent hosts.

Recent Findings: Molecular testing has identified that CMV infection is frequently present in cases of Posner-Schlossman and Fuchs, keratouveitis syndromes previously presumed to be idiopathic conditions. Ocular hypertension and endothelial cell loss are important complications of CMV keratouveitis and are likely mediated by viral invasion of the trabecular meshwork and corneal endothelium. Read More

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http://Insights.ovid.com/crossref?an=00055735-900000000-9924
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http://dx.doi.org/10.1097/ICU.0000000000000521DOI Listing
November 2018
6 Reads

Ocular Manifestations of Human Immunodeficiency Virus Infection at a Tertiary Referral Center in Taiwan.

Ocul Immunol Inflamm 2018 Sep 6:1-6. Epub 2018 Sep 6.

a Department of Ophthalmology , Kaohsiung Veterans General Hospital , Kaohsiung , Taiwan.

Purpose: To investigate the prevalence and characteristics of ocular manifestations of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) in patients treated at a tertiary referral center in Taiwan during a time of highly active antiretroviral therapy (HAART) Materials and Methods: A retrospective cohort study in Taiwan was performed between January 2006 and July 2016. Ocular examination and systemic information were recorded from the HIV-infected patients.

Results: 1242 patients with HIV/AIDS were identified. Read More

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http://dx.doi.org/10.1080/09273948.2018.1499939DOI Listing
September 2018
6 Reads

Tuberculosis treatment failure in AIDS: vengeance with renal and ocular manifestations.

BMJ Case Rep 2018 Aug 31;2018. Epub 2018 Aug 31.

Montefiore Medical Center, Bronx, New York, USA.

Tuberculosis treatment failure is not uncommon in patients with AIDS. Treatment failure is defined as a positive sputum smear or culture at month 5 or later in the course of the treatment. The clinical presentations in these patients show remarkable heterogeneity. Read More

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http://dx.doi.org/10.1136/bcr-2018-225955DOI Listing
August 2018
14 Reads

Clinical Manifestations and Ophthalmic Outcomes of Ocular Syphilis at a Time of Re-Emergence of the Systemic Infection.

Sci Rep 2018 Aug 13;8(1):12071. Epub 2018 Aug 13.

Flinders University College of Medicine and Public Health, Adelaide, Australia.

Recent reports from different world regions suggest ocular syphilis is re-emerging, in parallel with an increasing incidence of the systemic infection globally. We conducted a large observational study of 127 persons consecutively treated for ocular syphilis at public medical centers in Brazil over a 2.5-year period ending July 2015. Read More

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http://dx.doi.org/10.1038/s41598-018-30559-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089995PMC
August 2018
11 Reads

Ocular manifestations in patients attending antiretroviral therapy centre at a tertiary care hospital in Himachal Pradesh, India.

Indian J Med Res 2018 05;147(5):496-500

Department of Medicine, Dr. Rajendra Prasad Government Medical College, Kangra, India.

Background & Objectives: Ocular manifestations in HIV/AIDS patients range from adnexal disorders to the posterior segment disease. This study was aimed to evaluate the ocular manifestations, including vision-threatening manifestations in HIV-positive patients attending an antiretroviral therapy centre (ART) of a tertiary care hospital in north India and its association with the CD4+ cell count.

Methods: This cross-sectional study was conducted in the department of Ophthalmology in collaboration with the ART centre. Read More

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http://www.ijmr.org.in/text.asp?2018/147/5/496/238227
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http://dx.doi.org/10.4103/ijmr.IJMR_1037_15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094518PMC
May 2018
16 Reads

Kaposi's sarcoma of the conjunctiva and the eyelid leads to the diagnosis of human immunodeficiency virus infection - a case report.

BMC Cancer 2018 Jul 3;18(1):708. Epub 2018 Jul 3.

Department of Ophthalmology, Centro Hospitalar Vila Nova de Gaia/Espinho, Avenida Cidade de Montgeron, 212 -, 4490-402, Póvoa de Varzim, Portugal.

Background: The purpose of this case report is to describe a conjunctiva and eyelid Kaposi's sarcoma (KS) as the initial manifestation of acquired immunodeficiency syndrome (AIDS), which led to the diagnosis of HIV infection. There are only 3 reported cases of ocular KS as an initial manifestation of HIV infection.

Case Presentation: A 32-year old white man presented to our department with a 1 month history of eye redness. Read More

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http://dx.doi.org/10.1186/s12885-018-4611-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029361PMC
July 2018
5 Reads

Herpetic ocular manifestations in a patient with GATA2 deficiency.

Saudi J Ophthalmol 2018 Apr-Jun;32(2):164-166. Epub 2017 Nov 13.

12 de Octubre University Hospital, Ophthalmology Department, Complutense University, Madrid, Spain.

Specific genetic deficiencies are a rare cause that should be included in the diagnostic algorithm of disseminated herpetic lesions. The aim of this article is to describe the ocular herpetic manifestations in a rare genetic disorder called GATA2 deficiency. We present the clinical case of a 26-year-old male with dendritic ulcers in his cornea, marrow aplasia and idiopathic chronic lymphedema. Read More

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http://dx.doi.org/10.1016/j.sjopt.2017.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010607PMC
November 2017
19 Reads

Syphilis-Related Eye Disease Presenting as Bilateral Papilledema, Retinal Nerve Fiber Layer Hemorrhage, and Anterior Uveitis in a Penicillin-Allergic Patient.

Case Rep Infect Dis 2018 18;2018:2840241. Epub 2018 Feb 18.

University of Nebraska Medical Center, S. 42nd and Emile St., Omaha, NE, USA.

. is known as the "great masquerader" for its many presentations and ocular findings in patients who are infected and develop secondary and tertiary stage of syphilis. Syphilitic ocular manifestations include uveitis, chorioretinitis, retinitis, vasculitis, vitritis, and panuveitis all with or without decreased visual acuity. Read More

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http://dx.doi.org/10.1155/2018/2840241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835303PMC
February 2018
7 Reads

Ocular surface squamous neoplasia in HIV-infected patients: current perspectives.

HIV AIDS (Auckl) 2018 14;10:33-45. Epub 2018 Mar 14.

Operation Eyesight Universal Institute for Eye Cancer, LV Prasad Eye Institute, Hyderabad, India.

Ocular surface squamous neoplasia (OSSN) refers to a spectrum of conjunctival and corneal epithelial tumors including dysplasia, carcinoma in situ, and invasive carcinoma. In this article, we discuss the current perspectives of OSSN associated with HIV infection, focusing mainly on the epidemiology, pathophysiology, clinical manifestations, diagnosis, and treatment of these tumors in patients with HIV. Upsurge in the incidence of OSSN with the HIV pandemic most severely affected sub-Saharan Africa, due to associated risk factors, such as human papilloma virus and solar ultraviolet exposure. Read More

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http://dx.doi.org/10.2147/HIV.S120517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857154PMC
March 2018
2 Reads

Anterior segment and external ocular disorders associated with HIV infections in the era of HAART in Chiang Mai University Hospital, a prospective descriptive cross sectional study.

PLoS One 2018 21;13(2):e0193161. Epub 2018 Feb 21.

Ophthalmology department, Chiang Mai University Hospital, Chiang Mai, Thailand.

Human immunodeficiency virus (HIV) causes impairment to the human immune system which leads to immunocompromised conditions, including ocular complications. Several important HIV-associated disorders may involve the anterior segment, ocular surface, and adnexae organ such as dry eye, blepharitis which reduce quality of life of patients. In present, potent antiretroviral therapies HAART (highly active antiretroviral therapy) has improved the length and quality of life which may lead to an increased prevalence of anterior segment ocular disorders. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193161PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5821368PMC
May 2018
17 Reads

Secondary pulmonary syphilis: Case report and review of literature.

Ann Dermatol Venereol 2018 Apr 17;145(4):278-287. Epub 2018 Feb 17.

Service de dermatologie, hôpital Emile-Muller, GHR Mulhouse-Sud Alsace, 20, avenue du Dr-René-Laennec, 68100 Mulhouse, France.

Introduction: Syphilis is a sexually transmitted disease that can affect numerous organs in its secondary or tertiary stages. We describe a case of secondary syphilis with pulmonary involvement and we present a literature review.

Patients And Methods: A 69-year-old male patient was admitted to hospital for dyspnoea and extended papular exanthema with palmoplantar involvement. Read More

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http://dx.doi.org/10.1016/j.annder.2017.11.015DOI Listing
April 2018
4 Reads

Clinical manifestations and treatment outcomes of syphilitic uveitis in HIV-negative patients in China: A retrospective case study.

Medicine (Baltimore) 2017 Oct;96(43):e8376

aDepartment of Ophthalmology, The Affiliated Guangren Hospital of Xi'an Jiaotong University College of Medicine bDepartment of Otorhinolaryngology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

Syphilitic chorioretinitis should be included in differential diagnosis of any form of ocular inflammation. A significantly higher proportion of human immunodeficiency virus (HIV)-positive patients with ocular syphilis as compared to HIV-negative cases have been reported in published studies. However, the clinical signs and symptoms are more insidious in HIV-negative patients who are easily misdiagnosed. Read More

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http://dx.doi.org/10.1097/MD.0000000000008376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671864PMC
October 2017
31 Reads

[Neurosyphilis: A retrospective study of 13 cases at Strasbourg University Hospital].

J Fr Ophtalmol 2017 Oct 1;40(8):654-660. Epub 2017 Sep 1.

Laboratoire de bactériologie, CHU de Strasbourg, 67000 Strasbourg, France.

Objective: After a decade of constant decline, the number of syphilis cases has been steadily increasing since the 2000s, particularly in HIV infected patients. Neurosyphilis is a rare manifestation of this sexually transmitted disease for which we performed a retrospective study and analyzed clinical manifestations.

Patients And Methods: We reviewed retrospectively all the neurosyphilis cases admitted to Strasbourg University Hospital between 2004 and 2014. Read More

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http://dx.doi.org/10.1016/j.jfo.2017.03.007DOI Listing
October 2017
9 Reads

Neurosyphilis in Africa: A systematic review.

PLoS Negl Trop Dis 2017 Aug 31;11(8):e0005880. Epub 2017 Aug 31.

Clinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.

Introduction: Neurological involvement is one of the most important clinical manifestations of syphilis and neurological disease occurs in both early and late syphilis. The impact of HIV co-infection on clinical neurosyphilis remains unclear. The highest prevalence of both syphilis and HIV is in Africa. Read More

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http://dx.doi.org/10.1371/journal.pntd.0005880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597251PMC
August 2017
34 Reads

Management of a rare presentation of Vogt-Koyanagi-Harada disease in human immunodeficiency virus/acquired immunodeficiency disease syndrome patient.

Indian J Ophthalmol 2017 May;65(5):413-416

Department of Uvea and Ocular Pathology, Medical Research Foundation, Sankara Nethralaya, Chennai, Tamil Nadu, India.

Vogt-Koyanagi-Harada (VKH), a multisystem autoimmune bilateral panuveitis with systemic manifestations, is uncommon in immunocompromised patients such as human immunodeficiency virus (HIV)/acquired immunodeficiency disease syndrome (AIDS). We report a rare presentation of VKH in a 45-year-old HIV-positive female on highly active antiretroviral therapy (HAART) who presented with a history of recurrent panuveitis. A diagnosis of probable VKH was made based on ocular and systemic signs and symptoms. Read More

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http://dx.doi.org/10.4103/ijo.IJO_544_16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565895PMC
May 2017
29 Reads

Factors Contributing to Long-Term Severe Visual Impairment in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.

J Ophthalmol 2017 26;2017:2087578. Epub 2017 Mar 26.

Department of Ophthalmology, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

. To study the correlation between demographics and clinical variables and long-term severe visual impairment in patients with Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TEN). . Read More

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http://dx.doi.org/10.1155/2017/2087578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385247PMC
March 2017
9 Reads

Eye changes among HIV positive patients on antiretroviral therapy in Nepal.

Nepal J Ophthalmol 2016 01;8(15):62-70

Objective: To find out eye findings among HIV positive patients in the era of antiretroviral therapy. Method This Hospital based cross sectional descriptive study was carried at B. P. Read More

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http://dx.doi.org/10.3126/nepjoph.v8i1.16158DOI Listing
January 2016
1 Read

Uveitis as an initial manifestation of acquired immunodeficiency syndrome.

Int J STD AIDS 2017 10 15;28(12):1224-1228. Epub 2017 Feb 15.

1 Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.

Human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) is a multisystem disease that can involve the human eyes. Using ophthalmic examination records from January 2006 to November 2015, we retrospectively reviewed all patients who were diagnosed with HIV/AIDS in our hospital. The study was performed at a tertiary referral center in southern Taiwan. Read More

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http://dx.doi.org/10.1177/0956462417694569DOI Listing
October 2017
19 Reads

Testing for Zika virus infection in pregnancy: key concepts to deal with an emerging epidemic.

Am J Obstet Gynecol 2017 03 23;216(3):209-225. Epub 2017 Jan 23.

Departments of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Baylor College of Medicine, Houston, TX; National School for Tropical Medicine, Baylor College of Medicine, Houston, TX; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX; Departments of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Texas Children's Hospital, Houston, TX. Electronic address:

Zika virus is an emerging mosquito-borne (Aedes genus) arbovirus of the Flaviviridae family. Following epidemics in Micronesia and French Polynesia during the past decade, more recent Zika virus infection outbreaks were first reported in South America as early as May 2013 and spread to now 50 countries throughout the Americas. Although no other flavivirus has previously been known to cause major fetal malformations following perinatal infection, reports of a causal link between Zika virus and microcephaly, brain and ocular malformations, and fetal loss emerged from hard-hit regions of Brazil by October 2015. Read More

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http://dx.doi.org/10.1016/j.ajog.2017.01.020DOI Listing
March 2017
44 Reads

Ocular Syphilis - Eight Jurisdictions, United States, 2014-2015.

MMWR Morb Mortal Wkly Rep 2016 Nov 4;65(43):1185-1188. Epub 2016 Nov 4.

Ocular syphilis, a manifestation of Treponema pallidum infection, can cause a variety of ocular signs and symptoms, including eye redness, blurry vision, and vision loss. Although syphilis is nationally notifiable, ocular manifestations are not reportable to CDC. Syphilis rates have increased in the United States since 2000. Read More

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http://dx.doi.org/10.15585/mmwr.mm6543a2DOI Listing
November 2016
16 Reads

Non-human Immunodeficiency Virus-related Ocular Syphilis in a Korean Population: Clinical Manifestations and Treatment Outcomes.

Korean J Ophthalmol 2016 Oct 29;30(5):360-368. Epub 2016 Sep 29.

Department of Ophthalmology, Kyung Hee University Hospital, Kyung Hee University School of Medicine, Seoul, Korea.

Purpose: To describe the clinical manifestations and treatment outcomes of ocular syphilis in patients without human immunodeficiency virus (HIV) infection.

Methods: A total of 45 eyes from 39 patients with ocular syphilis confirmed by serologic tests were reviewed retrospectively. The included cases were all non-HIV-infected patients presenting with intraocular inflammation from 2002 to 2014 at Kyung Hee University Hospital. Read More

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http://dx.doi.org/10.3341/kjo.2016.30.5.360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5057012PMC
October 2016
10 Reads

Necrotizing retinitis due to syphilis in a patient with AIDS.

IDCases 2016 21;6:17-9. Epub 2016 Aug 21.

Indiana University Department of Medicine, United States.

The ocular manifestations of syphilis are varied. Ocular syphilis can occur during any stage of infection and involve virtually any part of the eye. In immunocompetent individuals, the most common etiologies include syphilitic uveitis. Read More

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http://dx.doi.org/10.1016/j.idcr.2016.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021766PMC
September 2016
10 Reads

Kaposi Sarcoma of the eyelid as an initial manifestation of AIDS.

Dermatol Online J 2016 Jul 15;22(7). Epub 2016 Jul 15.

Department of Dermatovenereology of Centro Hospitalar de Lisboa Norte, Lisboa, Portugal.

Kaposi sarcoma (KS) is a multifocal systemic disease that originates in the vascular endothelium related to Human Herpes Virus 8 (HHV-8). In the early 1980s the first series of cases of disseminated Kaposi Sarcoma in HIV infected patients were reported. However, with the advent of highly active antiretroviral therapy (HAART) since 1997, these cases are less frequently observed by clinicians. Read More

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July 2016
34 Reads

Don't Forget What You Can't See: A Case of Ocular Syphilis.

West J Emerg Med 2016 Jul 21;17(4):473-6. Epub 2016 Jun 21.

University of Texas, Health Science Center, San Antonio, Department of Emergency Medicine, San Antonio, Texas.

This case describes an emergency department (ED) presentation of ocular syphilis in a human immunodeficiency virus (HIV) infected patient. This is an unusual presentation of syphilis and one that emergency physicians should be aware of. The prevalence of syphilis has reached epidemic proportions since 2001 with occurrences primarily among men who have sex with men (MSM). Read More

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http://dx.doi.org/10.5811/westjem.2016.5.28933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4944808PMC
July 2016
15 Reads

Molecular Typing of Treponema pallidum in Ocular Syphilis.

Sex Transm Dis 2016 08;43(8):524-7

From the *Centers for Disease Control and Prevention, Atlanta, GA; †Department of Neurology, and ‡Department of Medicine (Infectious Diseases), University of Washington School of Medicine, Seattle, WA.

Background: Syphilis can have many clinical manifestations, including eye involvement, or "ocular syphilis." In 2015, an increase in reported cases of ocular syphilis and potential case clusters raised concern for an oculotropic strain of Treponema pallidum, the infectious agent of syphilis. Molecular typing was used to examine strains found in cases of ocular syphilis in the United States. Read More

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http://pdfs.journals.lww.com/stdjournal/2016/08000/Molecular
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http://dx.doi.org/10.1097/OLQ.0000000000000478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253705PMC
August 2016
23 Reads

Clinical manifestations and cerebrospinal fluid status in ocular syphilis in HIV-Negative patients.

BMC Infect Dis 2016 06 6;16:245. Epub 2016 Jun 6.

Department of Dermatology, Shanghai Xuhui Central Hospital, Shanghai, People's Republic of China.

Background: Syphilis with ocular involvement has reemerged as a critical health problem. The aim of the present study was to explore the clinical manifestations and cerebrospinal fluid (CSF) status in ocular syphilis in human immunodeficiency virus (HIV)-negative patients.

Methods: The clinical records of patients with ocular syphilis presenting to the Shanghai Xuhui Central Hospital in the period from January 2011 to December 2012 were retrospectively reviewed. Read More

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http://dx.doi.org/10.1186/s12879-016-1586-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895961PMC
June 2016
10 Reads

Analysis and Outcomes of Cataract Surgery in Patients with Acquired Immunodeficiency Syndrome.

Ocul Immunol Inflamm 2017 Aug 15;25(4):535-539. Epub 2016 Apr 15.

a National Healthcare Group Eye Institute Tan Tock Seng Hospital , Singapore.

Purpose: To investigate the surgical outcomes, complications and postoperative progression in HIV patients undergoing cataract surgery in a teaching hospital.

Methods: A retrospective cohort study of patients with HIV/AIDS who had cataract surgery from January 2000 until December 2011 at a tertiary referral multidisciplinary hospital in Singapore.

Results: We identified 44 eyes from 29 patients. Read More

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http://dx.doi.org/10.3109/09273948.2016.1158281DOI Listing
August 2017
8 Reads

Tuberculous Panophthalmitis with Lymphadenitis and Central Nervous System Tuberculoma.

Case Rep Infect Dis 2016 9;2016:6785382. Epub 2016 Mar 9.

Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Tuberculosis (TB) is a serious infectious disease that spreads globally. The ocular manifestations of TB are uncommon and diverse. TB panophthalmitis has been rarely reported. Read More

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http://dx.doi.org/10.1155/2016/6785382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804051PMC
April 2016
4 Reads

MULTIFOCAL CHOROIDITIS IN DISSEMINATED SPOROTRICHOSIS IN PATIENTS WITH HIV/AIDS.

Retin Cases Brief Rep 2017 Winter;11(1):67-70

*Laboratório de Pesquisa Clínica em Oftalmologia Infecciosa, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil; †Laboratório de Pesquisa Clínica em Dermatologia Infecciosa, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil; ‡Centro Hospitalar do Instituto Nacional de Infectologia, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil; and §Laboratório de Micologia, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.

Purpose: In this article, the authors describe multifocal choroiditis related to disseminated sporotrichosis in patients with HIV/AIDS.

Methods: We conducted a retrospective observational study of three patients infected with HIV who presented with disseminated sporotrichosis characterized by cutaneous lesions, multifocal choroiditis, and other manifestations, including osteomyelitis and involvement of the bone marrow, larynx, pharynx, and nasal and oral mucosa.

Results: Five eyes of three patients with HIV/AIDS showed multifocal choroiditis related to disseminated sporotrichosis. Read More

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http://dx.doi.org/10.1097/ICB.0000000000000290DOI Listing
April 2017
9 Reads

Ocular Manifestations in Patients with Human Immunodeficiency Virus Infection in the Pre-HAART Versus the HAART Era in the North Indian Population.

Ocul Immunol Inflamm 2017 Jun 24;25(3):396-404. Epub 2016 Feb 24.

b Department of Ophthalmology , Advanced Eye Centre, Post Graduate Institute of Medical Education and Research (PGIMER) , Chandigarh , India.

Purpose: To compare changes in the demographic profile and ocular manifestations in patients with HIV in the pre-HAART and HAART era in North India.

Methods: In this single-center cross-sectional study, 100 HIV patients receiving HAART and 96 HIV patients in the pre-HAART era were enrolled. Prevalence of ocular manifestations of HIV was calculated for both cohorts. Read More

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http://dx.doi.org/10.3109/09273948.2015.1133837DOI Listing
June 2017
11 Reads

[Ocular immune reconstitution inflammatory syndrome].

Authors:
N Ma J J Ye

Zhonghua Yan Ke Za Zhi 2016 Feb;52(2):150-3

Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.

Immune reconstitution inflammatory syndrome (IRIS) is a collection of inflammatory disorders associated with paradoxical worsening of preexisting infectious processes or emerging diseases or even dead after the initiation of highly active antiretroviral therapy (HAART) in human immunodeficiency virus (HIV) infected individuals in a period of recovery of immune function. Ocular immune reconstitution inflammatory syndrome is mainly caused by cytomegalovirus which performing a series of ocular inflammation accompanied with the increase of CD4+ T lymphocytes, such as cytomegalovirus retinitis, after HAART. With HAART widely used, the patients of IRIS gradually increased. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0412-4081.2016.02.017DOI Listing
February 2016
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Rheumatoid polyarthritis suspected in an HIV patient with scleritis, peripheral ulcerative keratitis, and anterior uveitis.

Int Med Case Rep J 2016 4;9:19-24. Epub 2016 Feb 4.

Université de Yaoundé 1, Yaoundé, Cameroon.

Introduction: Scleritis and peripheral ulcerative keratitis are ocular manifestations found in many inflammations and infections. Therefore, their association should prompt a search for inflammatory or infectious causes that may be life-threatening, especially in the context of AIDS due to HIV infection.

Findings: We report the case of a 37-year-old female, first seen in 2011 with a nodular scleritis in the right eye and a peripheral ulcerative keratitis, a necrotizing scleritis, and a granulomatous anterior uveitis in the left eye, in the context of chronic polyarthropathies that had evolved over 6 months. Read More

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http://dx.doi.org/10.2147/IMCRJ.S94194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745951PMC
February 2016
3 Reads

[Ocular manifestations of syphilitic uveoretinitis in patients co-infected with human immunodeficiency virus].

Zhonghua Yan Ke Za Zhi 2015 Oct;51(10):739-45

Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai Key Laboratory of Visual Impairment and Restoration, Shanghai 200031, China; Email:

Objective: To investigate the clinical manifestations of syphilitic uveoretinitis in patients co-infected with human immunodeficiency virus (HIV).

Methods: Uveoretinitis patients presenting between January 2008 and December 2014 at Eye and ENT Hospital of Fudan University were collected. Patients were selected with positive serologic tests, including rapid plasma regain titer (RPR) > 1:8, treponema pallidum particle agglutination assay (TPPA) and human immunodeficiency virus (HIV). Read More

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October 2015
13 Reads

Ocular Surface Squamous Neoplasia (OSSN): A Retrospective Study.

J Clin Diagn Res 2015 Nov 1;9(11):NC10-3. Epub 2015 Nov 1.

Assistant Professor, Department of Pathology, Osmania Medical College , Hyderabad, India .

Background: Ocular surface squamous neoplasia (OSSN) is a term used to describe neoplastic epithelial abnormalities of conjunctiva and cornea, ranging from Squamous Dysplasia to Invasive Squamous Cell Carcinoma. In recent times, the incidence of OSSN seems to be on the rise, especially in developing countries like India.

Aim: To analyse demographic characteristics and compare the clinical presentation, treatment outcomes, and histopathology features of Ocular Surface Squamous Neoplasia (OSSN). Read More

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http://dx.doi.org/10.7860/JCDR/2015/16207.6791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668444PMC
November 2015
5 Reads

[Ocular syphilis: A retrospective study of 27 cases in Nantes University Hospital (France) from 2000 to 2013].

Rev Med Interne 2015 Nov 19;36(11):722-7. Epub 2015 Sep 19.

Service d'ophtalmologie, CHU de Nantes, 1, place Alexis-Ricordeau, 44000 Nantes, France.

Introduction: Syphilis may manifest as several distinct ophthalmological forms. The main objective of our study was to describe the diagnostic, therapeutic data and prognosis of ocular syphilis.

Patients And Methods: We retrospectively analysed the cases of syphilitic uveitis diagnosed in the University Hospital of Nantes between 2000 and 2013. Read More

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http://dx.doi.org/10.1016/j.revmed.2015.07.008DOI Listing
November 2015
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Clinical and laboratory characteristics of ocular syphilis: a new face in the era of HIV co-infection.

J Ophthalmic Inflamm Infect 2015 Dec 22;5(1):56. Epub 2015 Aug 22.

Department of Ophthalmology, USC Eye Institute, Keck School of Medicine of the University of Southern California, 1450 San Pablo St., Suite 4000, Los Angeles, CA, 90033, USA,

Background: Ocular syphilis is reemerging as an important cause of uveitis in the new era of common co-infection with HIV. This study will reveal the clinical and laboratory characteristics in the group of individuals co-infected with ocular syphilis and HIV compared with HIV-negative individuals. In this retrospective observational case series, medical records of patients diagnosed with ocular syphilis with serologic support from 2008 to 2014 were reviewed. Read More

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http://dx.doi.org/10.1186/s12348-015-0056-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546070PMC
December 2015
6 Reads

Ocular syphilis: an alarming infectious eye disease.

Int J Clin Exp Med 2015 15;8(5):7770-7. Epub 2015 May 15.

Department of Ophthalmology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine Hangzhou, Zhejiang, P. R. China.

Background: To describe the clinical manifestations and ancillary examination outcomes of ocular syphilis in Southeast China.

Materials And Methods: This is a retrospective, nonrandom case study. Demographic information, serum and cerebrospinal fluid (CSF) test results, and findings of fundus fluorescein angiography (FFA), indocyanine green angiography (ICGA), and spectral domain optical coherence tomography (SD-OCT) were analyzed. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509273PMC
July 2015
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Predictors of HIV/AIDS Related Ocular Manifestations among HIV/AIDS Patients in Felege Hiwot Referral Hospital, Northwest Ethiopia.

J Ophthalmol 2015 27;2015:965627. Epub 2015 Apr 27.

Department of Public Health, College of Medicine and Health Sciences, Bahir Dar University, P.O. Box 79, Bahir Dar, Ethiopia.

Background. Ocular manifestations in people living with HIV/AIDS are varied and affect almost all the structures of eye leading to visual impairment or blindness. Therefore, the aim of this study was to identify the predictors of HIV related ocular manifestation among ART clinic clients. Read More

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http://www.hindawi.com/journals/joph/2015/965627/
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http://dx.doi.org/10.1155/2015/965627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427099PMC
May 2015
2 Reads

Clinical manifestations of herpes zoster, its comorbidities, and its complications in north of iran from 2007 to 2013.

Neurol Res Int 2015 29;2015:896098. Epub 2015 Mar 29.

Health Management Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Background. Herpes zoster infection is a painful worldwide disease. Inappropriate and delayed treatment causes prolongation of the disease with debilitating symptoms and postherpetic neuralgia. Read More

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http://downloads.hindawi.com/journals/nri/2015/896098.pdf
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http://www.hindawi.com/journals/nri/2015/896098/
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http://dx.doi.org/10.1155/2015/896098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393919PMC
April 2015
12 Reads

Syphilitic uveitis and optic neuritis in Sydney, Australia.

Br J Ophthalmol 2015 Sep 18;99(9):1215-9. Epub 2015 Mar 18.

Save Sight Institute, Discipline of Ophthalmology, Sydney Eye Hospital Campus, The University of Sydney, Sydney, Australia.

Aims: To describe ocular syphilis presentations to a tertiary referral eye hospital over a 5-year period and to document HIV coinfection frequency.

Methods: A retrospective chart review was conducted of consecutive ocular syphilis presentations to Sydney Eye Hospital from 2007 to 2012. Inclusion criteria were positive syphilis serology, ocular inflammation on clinical examination and appropriate syphilis treatment. Read More

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http://bjo.bmj.com/content/99/9/1215.full.pdf
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http://bjo.bmj.com/lookup/doi/10.1136/bjophthalmol-2014-3061
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http://dx.doi.org/10.1136/bjophthalmol-2014-306168DOI Listing
September 2015
7 Reads

Orbital manifestations in patients with acquired immunodeficiency syndrome.

Nepal J Ophthalmol 2014 Jul-Dec;6(2):205-19

Guru Nanak Eye Centre and Maulana Azad Medical College, New Delhi, India.

Introduction: The orbital manifestations of acquired immunodeficiency syndrome(AIDS) are uncommon.

Objective: To provide a review of orbital manifestations of AIDS, the predisposing factors, investigations, treatment and outcome.

Materials And Methods: Meticulous and systematic literature search of Pubmed to identify manuscripts describing orbital manifestations of AIDS was done and the articles were reviewed. Read More

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http://dx.doi.org/10.3126/nepjoph.v6i2.11710DOI Listing
September 2015
1 Read

[Clinical and paraclinical features of syphilitic uveitis].

J Fr Ophtalmol 2015 Mar 28;38(3):220-8. Epub 2015 Jan 28.

Service d'ophtalmologie, hôpital Édouard-Herriot, 5, place d'Arsonval, 69003, Lyon, France.

Introduction: Syphilis, caused by Treponema pallidum agent, results in polymorphic and non-specific ocular manifestations. Early diagnosis and institution of individualized treatment play a large role in the prognosis. The increase in syphilis over the past several years requires the ophthalmologist to consider this diagnosis in the setting of any intraocular inflammatory involvement. Read More

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http://dx.doi.org/10.1016/j.jfo.2014.09.011DOI Listing
March 2015
22 Reads

Ophthalmic manifestations of perinatally acquired HIV in a US cohort of long-term survivors.

Br J Ophthalmol 2015 May 21;99(5):650-3. Epub 2014 Nov 21.

Department of Pediatrics, University of California San Francisco, San Francisco, California, USA.

Background/aims: To determine the ophthalmic manifestations of HIV in a cohort of long-term survivors of perinatally acquired HIV.

Methods: Twenty-two patients with perinatally acquired HIV who were aged ≥12 years were prospectively studied at a university clinic. They underwent complete ophthalmic examinations and fundus photography. Read More

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http://dx.doi.org/10.1136/bjophthalmol-2014-305557DOI Listing
May 2015
11 Reads