191,919 results match your criteria Ocular Hypotony


Non-GVHD ocular complications after hematopoietic cell transplantation: expert review from the Late Effects and Quality of Life Working Committee of the CIBMTR and Transplant Complications Working Party of the EBMT.

Biol Blood Marrow Transplant 2018 Dec 3. Epub 2018 Dec 3.

Department of Ophthalmology, Hospital Universitario Puerta de Hierro, Madrid, Spain.

Non-graft-versus-host disease (non-GVHD) ocular complications are generally uncommon after hematopoietic cell transplantation (HCT), but can cause prolonged morbidity affecting activities of daily living and quality of life. Here we provide an expert review of non-GVHD ocular complications in a collaboration between transplant physicians and ophthalmologists through the Late Effects and Quality of Life Working Committee of the Center for International Blood and Marrow Transplant Research and the Transplant Complications Working Party of the European Society of Blood and Marrow Transplantation. Complications discussed in this review include cataracts, glaucoma, ocular infections, ocular involvement with malignancy, ischemic microvascular retinopathy, central retinal vein occlusion, retinal hemorrhage, retinal detachment and ocular toxicities associated with medications. Read More

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December 2018
2 Reads

Binocular Summation for Reflexive Eye Movements: A Potential Diagnostic Tool for Stereodeficiencies.

Invest Ophthalmol Vis Sci 2018 Dec;59(15):5816-5822

Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health, U.S. Department of Health and Human Services, Bethesda, Maryland, United States.

Purpose: Stereoscopic vision, by detecting interocular correlations, enhances depth perception. Stereodeficiencies often emerge during the first months of life, and left untreated can lead to severe loss of visual acuity in one eye and/or strabismus. Early treatment results in much better outcomes, yet diagnostic tests for infants are cumbersome and not widely available. Read More

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December 2018

Opposing Effects of PPARα Agonism and Antagonism on Refractive Development and Form Deprivation Myopia in Guinea Pigs.

Invest Ophthalmol Vis Sci 2018 Dec;59(15):5803-5815

School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.

Purpose: To determine if drug-induced peroxisome proliferator-activated receptor α (PPARα) signal pathway modulation affects refractive development and myopia in guinea pigs.

Methods: Pigmented guinea pigs were randomly divided into normal vision (unoccluded) and form deprivation myopia (FDM) groups. Each group received daily peribulbar injections of either a vehicle or (1) PPARα agonist, GW7647, clofibrate, or bezafibrate or (2) PPARα antagonist, GW6471, for 4 weeks. Read More

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December 2018

Staphylococcus aureus from ocular and otolaryngology infections are frequently resistant to clinically important antibiotics and are associated with lineages of community and hospital origins.

PLoS One 2018 6;13(12):e0208518. Epub 2018 Dec 6.

Infectious Diseases Institute, Department of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States of America.

Staphylococcus aureus is an important human pathogen that causes serious antibiotic-resistant infections. Its population structure is marked by the appearance and dissemination of successful lineages across different settings. To begin understanding the population structure of S. Read More

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December 2018
1 Read

Association Between Noninfectious Uveitis and Psychological Stress.

JAMA Ophthalmol 2018 Dec 6. Epub 2018 Dec 6.

Francis I. Proctor Foundation, University of California, San Francisco.

Importance: Uveitis involves dysregulation of the ocular immune system. Stress has been shown to affect immune function, but it is unclear whether there is an association between stress and uveitis.

Objective: To determine whether having uveitis is associated with psychological stress. Read More

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December 2018
2 Reads

Preliminary experience of the use of high-resolution skin ultrasound for the evaluation of extrathyroideal manifestations of Graves' disease and response to UVA-1 phototherapy.

Photodermatol Photoimmunol Photomed 2018 Dec 6. Epub 2018 Dec 6.

Dermatology Unit, Department of Medical, Surgical and Neuro-Sciences, University of Siena, Siena, Italy.

Graves' orbitopathy (GO) and pre-tibial mixedema (PTM) are autoimmune manifestation sharing the same etiology and histopathology, a chronic course and a frustrating treatment. Current management include topical and systemic corticosteroid as first line therapy, whereas cyclosporine, surgery and orbital radiotherapy are indicated for severe GO with variable results and mostly temporary remissions. In particular, keratopath and photophobia, due to exophthalmos and eyelid retraction, impaired eye mobility and diplopia due to the compression of optic nerve and extra-ocular muscles are usually minimally modified, as well as leg plaques/nodules and lymphoedema. Read More

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December 2018
2 Reads

The Ocular Status of Cystinosis Patients Receiving a Hospital Pharmacy-Made Preparation of Cysteamine Eye Drops: A Case Series.

Ophthalmol Ther 2018 Dec 5. Epub 2018 Dec 5.

Manchester Royal Eye Hospital, Manchester Academic Health Science Centre, Manchester, UK.

Introduction: Infantile nephropathic cystinosis (INC) is an autosomal recessive lysosomal disorder in which patients develop deposits of cystine crystals in their kidneys and corneas from a young age.

Methods: We conducted a retrospective analysis of children with INC seen by ophthalmologists at the Manchester Royal Eye Hospital between 2002 and 2018, to evaluate clinical findings, symptoms and treatment.

Results: Twenty-two children diagnosed with INC from age 0 (prenatally) to 11 years were assessed. Read More

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December 2018
3 Reads

Chloroquine Protects Human Corneal Epithelial Cells from Desiccation Stress Induced Inflammation without Altering the Autophagy Flux.

Biomed Res Int 2018 1;2018:7627329. Epub 2018 Nov 1.

GROW Research Laboratory, Narayana Nethralaya Foundation, Bangalore, Karnataka, India.

Dry eye disease (DED) is a multifactorial ocular surface disorder affecting millions of individuals worldwide. Inflammation has been associated with dry eye and anti-inflammatory drugs are now being targeted as the alternate therapeutic approach for dry eye condition. In this study, we have explored the anti-inflammatory and autophagy modulating effect of chloroquine (CQ) in human corneal epithelial and human corneal fibroblasts cells exposed to desiccation stress, (an model for DED). Read More

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November 2018

Composition and Comparison of the Ocular Surface Microbiome in Infants and Older Children.

Transl Vis Sci Technol 2018 Nov 30;7(6):16. Epub 2018 Nov 30.

Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.

Purpose: Unlike other microbiomes of the body, the composition of the ocular surface microbiome (OSM) in children has yet to be thoroughly explored. Our goal was to evaluate the OSM in young infants and compare its composition to older children using both culture dependent and independent methodologies to assess for differences with age.

Methods: Prospective, observational, cross-sectional study of children <18 years of age at a university-based institution. Read More

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November 2018
1 Read

Evaluation of RETICs Glaucoma Diagnostic Calculators in Preperimetric Glaucoma.

Transl Vis Sci Technol 2018 Nov 30;7(6):13. Epub 2018 Nov 30.

Institut Catalá de Retina, Universitat Internacional de Catalunya, Barcelona, Spain.

Purpose: To evaluate two glaucoma diagnostic calculators (GDC) in a group of eyes with preperimetric glaucoma (PPG).

Methods: All eyes ( = 265) included in this study had ocular hypertension with normal visual fields (VFs) on repeated VF tests. PPG was defined as progression in the Guided Progression Analysis software from Cirrus-optical coherence tomography (GPA-OCT). Read More

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November 2018

FGF21 underlies a hormetic response to metabolic stress in methylmalonic acidemia.

JCI Insight 2018 Dec 6;3(23). Epub 2018 Dec 6.

Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, Maryland, USA.

Methylmalonic acidemia (MMA), an organic acidemia characterized by metabolic instability and multiorgan complications, is most frequently caused by mutations in methylmalonyl-CoA mutase (MUT). To define the metabolic adaptations in MMA in acute and chronic settings, we studied a mouse model generated by transgenic expression of Mut in the muscle. Mut-/-;TgINS-MCK-Mut mice accurately replicate the hepatorenal mitochondriopathy and growth failure seen in severely affected patients and were used to characterize the response to fasting. Read More

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December 2018
2 Reads

Associations of greenness, greyness and air pollution exposure with children's health: a cross-sectional study in Southern Italy.

Environ Health 2018 Dec 5;17(1):86. Epub 2018 Dec 5.

National Research Council, Institute of Biomedicine and Molecular Immunology, via Ugo La Malfa 153, 90146, Palermo, Italy.

Background: Due to the complex interplay among different urban-related exposures, a comprehensive approach is advisable to estimate the health effects. We simultaneously assessed the effect of "green", "grey" and air pollution exposure on respiratory/allergic conditions and general symptoms in schoolchildren.

Methods: This study involved 219 schoolchildren (8-10 years) of the Municipality of Palermo, Italy. Read More

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December 2018

Diagnostic and prognostic value of the optic nerve sheath diameter with respect to the intracranial pressure and neurological outcome of patients following hemicraniectomy.

BMC Neurol 2018 Dec 5;18(1):199. Epub 2018 Dec 5.

Department of Emergency Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, No. 88, Jiefang Road, Hangzhou City, 310009, Zhejiang Province, China.

Background: In cases showing cerebrospinal fluid (CSF) redistribution as a compensatory mechanism in acute intracranial hypertension, the optic nerve sheath diameter (ONSD) can be used to estimate intracranial pressure (ICP). However, it remains unclear whether the ONSD can be applied in patients with skull defects after a craniectomy, because the primary injury or surgical craniectomy may alter the dynamics of the CSF circulation or structure of the optical nerve sheath. This study explored the value of the ONSD in patients after a hemicraniectomy. Read More

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December 2018

Review of Ocular Manifestations of Joubert Syndrome.

Genes (Basel) 2018 Dec 4;9(12). Epub 2018 Dec 4.

Department of Ophthalmology, Stanford University School of Medicine, 1651 Page Mill Road, Palo Alto, CA 94305, USA.

Joubert syndrome is a group of rare disorders that stem from defects in a sensory organelle, the primary cilia. Affected patients often present with disorders involving multiple organ systems, including the brain, eyes, and kidneys. Common symptoms include breathing abnormalities, mental developmental delays, loss of voluntary muscle coordination, and abnormal eye movements, with a diagnostic "molar tooth" sign observed by magnetic resonance imaging (MRI) of the midbrain. Read More

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December 2018
1 Read

Is Sjögren's syndrome dry eye similar to dry eye caused by other etiologies? Discriminating different diseases by dry eye tests.

PLoS One 2018 3;13(12):e0208420. Epub 2018 Dec 3.

Department of Ophthalmology, Otorhinolaryngology and Head & Neck Surgery, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.

Purpose: Dry Eye Disease (DED) is part of several conditions, including Sjögren's syndrome (SS) and no single test to diagnosis DED. The present study intends to evaluate whether a set of signs and symptoms of DED can distinguish: a) SS from other non-overlapping systemic diseases related to DED; b) primary and secondary SS.

Methods: 182 consecutive patients with DED were evaluated under five groups: SS, graft-versus-host disease (GVHD), Graves' orbitopathy (GO), diabetes mellitus (DM), glaucoma under treatment with benzalkonium chloride medications (BAK). Read More

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December 2018

2018 American Academy of Optometry Ocular Photography Contest.

Authors:

Optom Vis Sci 2018 Dec;95(12):1162-1165

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December 2018

Evaluation of Ocular Perfusion in Alzheimer's Disease Using Optical Coherence Tomography Angiography.

J Alzheimers Dis 2018 Nov 26. Epub 2018 Nov 26.

Department of Ophthalmology, University of Muenster Medical Center, Muenster, Germany.

Background: There is increasing evidence for the involvement of cerebrovascular factors in Alzheimer's disease (AD).

Objective: To evaluate retinal and optic nerve head perfusion in patients with AD using optical coherence tomography angiography (OCTA), and to analyze the correlations of quantitative OCTA metrics with AD pathology and vascular cerebral lesions in AD patients.

Methods: 36 eyes of 36 patients with AD (study group) and 38 eyes of 38 healthy subjects (control group) were prospectively included in this study. Read More

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November 2018

Evidence of retinal degeneration in Wolfram syndrome.

Ophthalmic Genet 2018 Dec 3:1-5. Epub 2018 Dec 3.

b Cole Eye Institute , Cleveland Clinic , Cleveland , OH , USA.

Purpose: Wolfram syndrome is characterized by early onset diabetes mellitus, diabetes insipidus, deafness, and optic atrophy, but retinal degeneration has not been described as a major component of the phenotype. We present two cases with Wolfram syndrome and evidence of retinal degeneration.

Materials And Methods: Observational case series. Read More

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December 2018

Fundamentals, challenges, and nanomedicine-based solutions for ocular diseases.

Wiley Interdiscip Rev Nanomed Nanobiotechnol 2018 Dec 3:e1548. Epub 2018 Dec 3.

Department of Biological Sciences and Bioengineering, Indian Institute of Technology Kanpur, Kanpur, India.

The eye consists of sensitive, compactly adjoined tissue structures which act as strong physical (static) and physiological (dynamic) barriers that prevent entry of foreign bodies into the eye. Together, these barriers reduce the bioavailability of topically and intraocularly administered medicaments thus demanding frequent drug administration for the treatment of chronic eye diseases. Hence, development of drug delivery systems (DDS) that can be retained in ocular tissues for longer durations can help to reduce the frequency of drug administration, whereas, delivery systems that traverse through ocular barriers may offer higher bioavailability of administered drugs to otherwise inaccessible ocular tissues. Read More

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December 2018

Consanguinity and its association with visual impairment in southern India: the Pavagada Pediatric Eye Disease Study 2.

J Community Genet 2018 Dec 1. Epub 2018 Dec 1.

University of Minnesota Medical School, Duluth campus, Minneapolis, MN, USA.

To determine the association of consanguinity with the occurrence of genetically transmitted eye diseases in rural and urban populations in Pavagada and Madhugiri taluks, Karnataka state, south India. This study was part of a population based cross-sectional prevalence survey, "The Pavagada pediatric eye disease study 2." As a part of the demographic data, trained investigators collected information on consanguinity from the parents of children identified for the study. Read More

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December 2018

Quantitative analysis of the retinal nerve fiber layer, ganglion cell layer and optic disc parameters by the swept source optical coherence tomography in patients with migraine and patients with tension-type headache.

Acta Neurol Belg 2018 Nov 30. Epub 2018 Nov 30.

Department of Neurology, Keçiören Training and Research Hospital, Ankara, Turkey.

The aim of the study was to measure the thicknesses of the inner retinal segments and optic nerve head (ONH) parameters in migraineurs and patients with tension-type headache (TTH) in headache-free period using swept source optical coherence tomography (SS-OCT) and to compare the outcomes with each other and those of healthy subjects. The study population consisted of 23 migraineurs, 22 TTH patients, and 25 controls with a best-corrected visual acuity of 20/20 and without a history of systemic or ocular disease. Macular ganglion cell inner plexiform layer (mGCIPL), macular ganglion cell complex (mGCC), circumpapillary retinal nerve fiber layer (cpRNFL), and ONH parameters were evaluated using SS-OCT, and the areas under the receiver-operating characteristic (ROC) curves were calculated to determine the ability of these parameters to distinguish between the patient and normal eyes. Read More

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November 2018

Differences of body height, axial length, and refractive error at different ages in Kumejima study.

Graefes Arch Clin Exp Ophthalmol 2018 Nov 30. Epub 2018 Nov 30.

Department of Ophthalmology, Kanto Central Hospital, Tokyo, Japan.

Purpose: To determine the relationships between the axial length (AL), refractive error (RE), and body height (BH) at different ages of a genetically-stable population in Kumejima, Japan.

Methods: Cross-sectional, population-based study. Residents of Kumejima who were ≥ 40-years old were studied. Read More

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November 2018

Bilateral combined anterior and posterior lenticonus in Alport's Syndrome.

Rom J Ophthalmol 2018 Jul-Sep;62(3):228-230

Department of Ophthalmology, Gajra Raja Medical College, Gwalior, India.

Alport's syndrome is an inherited disease characterized by hearing loss, progressive renal failure and ocular abnormalities like anterior lenticonus, corneal opacities, cataract, fleck retinopathies, and temporal retinal thinning. To have anterior and posterior lenticonus in the same eye in this syndrome is a rare finding and only a few such reports are available. Hereby, we report a case of a 22-year-old male with bilateral combined anterior and posterior lenticonus with sensorineural deafness and nephritis leading to the diagnosis of Alport's syndrome. Read More

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December 2018

Ocular structures in a mature ovarian teratoma.

Am J Ophthalmol Case Rep 2019 Mar 8;13:20-21. Epub 2018 Nov 8.

Department of Ophthalmology, Storm Eye Institute, Medical University of South Carolina, Charleston, SC, USA.

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Exposure, entropion, and bilateral corneal ulceration in a newborn as a manifestation of chromosome 22 q11.2 duplication syndrome.

Am J Ophthalmol Case Rep 2019 Mar 4;13:16-19. Epub 2018 Nov 4.

Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.

Purpose: Chromosome 22q11.2 micro-duplication syndrome (MDS), is a rare autosomal dominant condition, with a highly variable phenotype that ranges from unremarkable and asymptomatic, to fatal due to cardiovascular defects. Hypertelorism, downslanting palpebral fissures, superior displacement of the eyebrows, and ptosis are the most commonly reported ocular manifestations. Read More

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An unusual orbital tumor in an adult: Granuloma annulare.

Am J Ophthalmol Case Rep 2019 Mar 14;13:9-12. Epub 2018 Nov 14.

MUHC - McGill University Ocular Pathology Laboratory, 1001 Boul Decarie, Block E, E02.6217, Montreal, QC, H4A 3J1, Canada.

Purpose: Granuloma annulare (GA) is a rare clinical entity that does not classically arise from the peri-orbital area in adults. The purpose of this case report is to present a 69-year-old female with GA of the orbit. As well, the pathological and immunohistochemical features of these tumors will be discussed. Read More

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Adult conjunctivitis secondary to dual infection with and - A case report.

Am J Ophthalmol Case Rep 2019 Mar 14;13:6-8. Epub 2018 Nov 14.

Manchester Royal Eye Hospital, Oxford Road, Manchester, M13 9WL, UK.

Purpose: Although and are the commonest sexually transmitted infections in England, reports of ocular co-infection in the literature are limited. We report such a case which responded well to treatment, and discuss the literature and evidence currently available with regards to management of these cases.

Observations: The patient is a 48-year-old bisexual gentleman who presented to the eye clinic of a UK hospital with redness, discharge and blurred vision in his left eye for one week. Read More

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Combined flanged intrascleral intraocular lens fixation with corneal transplant.

Am J Ophthalmol Case Rep 2019 Mar 10;13:1-5. Epub 2018 Nov 10.

Medical University of South Carolina, USA.

Purpose: To report clinical outcomes and surgical technique of flanged intrascleral intraocular lens fixation with double-needle combined with either penetrating keratoplasty (PKP) or ultrathin Descemet-stripping automated endothelial keratoplasty (UT-DSAEK).

Observations: Five patients underwent combined flanged intrascleral intraocular lens fixation with double-needle technique and keratoplasty. Three patients underwent triple procedure (open sky intrascleral intraocular lens fixation with double-needle and PKP) secondary to ocular trauma or a failed corneal transplant. Read More

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Optical Rehabilitation of a Patient with Keratoconus and Nystagmus.

Med Hypothesis Discov Innov Ophthalmol 2018 ;7(4):183-189

Kentucky College of Optometry, University of Pikeville, Pikeville, KY, USA.

Keratoconus is a progressive corneal disease characterized by bilateral yet usually asymmetric thinning of the cornea with an onset typically in teenage years. While it often presents as an isolated condition, keratoconus may also be associated with many systemic and/or ocular diseases, such as connective tissue and chromosomal disorders. Its association with nystagmus has been described in Leber's congenital amaurosis, where patients also exhibit abnormal pupillary responses, early-onset retinal dystrophy, mental developmental delays, and eventual blindness. Read More

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January 2018
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Repeatability and Reproducibility of Peripapillary Choroidal Thickness Using a Medical Image-Processing Software.

Med Hypothesis Discov Innov Ophthalmol 2018 ;7(4):163-168

Ophthalmology Department, Egas Moniz Hospital, CHLO, Lisbon, Portugal.

Although choroid has been shown to have a vital role in the pathophysiology of many ocular diseases, its role in the pathogenesis of several other conditions remains uncertain. The authors propose a novel methodology to establish a more accurate Peripapillary Choroidal Thickness (PPCT), using an image-processing software. This study sought to evaluate the reproducibility and repeatability of PPCT evaluation with ImageJ software in healthy volunteers. Read More

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January 2018

A Review of Antimicrobial Therapy for Infectious Uveitis of the Posterior Segment.

Med Hypothesis Discov Innov Ophthalmol 2018 ;7(4):140-155

UCL Institute of Ophthalmology, Moorfields Eye Hospital, London, UK.

Treatment of infectious posterior uveitis represents a therapeutic challenge for ophthalmologists. The eye is a privileged site, maintained by blood ocular barriers, which limits penetration of systemic antimicrobials into the posterior segment. In addition, topical and subconjunctival therapies are incapable of producing sufficient drug concentrations, intraocularly. Read More

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January 2018

State-of-the-art assessment allows for improved vestibular evoked myogenic potential test-retest reliability.

Audiol Res 2018 Oct 20;8(2):212. Epub 2018 Sep 20.

School of Speech-Language Pathology and Audiology, Faculty of Medicine, University of Montreal.

The goal of the present study was to evaluate the test-retest reliability values of myogenic responses using the latest guidelines for vestibular assessment. Twenty-two otologically and neurologically normal adults were assessed twice, on two different days. The analyses were carried out using interclass correlations. Read More

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October 2018
2 Reads

Child presenting with ocular ecchymosis.

Oman J Ophthalmol 2018 Sep-Dec;11(3):303

Chandigarh Laser Eye Center, Faridabad, Haryana, India.

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December 2018

Isolated unilateral eyelid Rosai-Dorfman disease.

Oman J Ophthalmol 2018 Sep-Dec;11(3):300-302

Ophthalmic Pathology Service, Apollo Health City, Hyderabad, Telangana, India.

Isolated eyelid Rosai-Dorfman disease without orbital disease or systemic involvement is very rare and needs a high degree of suspicion. In this report, we describe a 16-year-old boy who presented with isolated eyelid Rosai-Dorfman disease involving the right upper eyelid. The lesion was treated by surgical debulking followed by intralesional steroid injection for the residual lesion. Read More

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December 2018

Rosai-Dorfman disease with isolated lacrimal gland enlargement.

Oman J Ophthalmol 2018 Sep-Dec;11(3):297-299

Department of Orbit, Oculoplasty and Ocular Oncology, Giridhar Eye Institute, Kochi, Kerala, India.

Rosai-Dorfman Disease also called as Sinus Histiocytosis with Massive Lymphadenopathy is a rare, benign, idiopathic histiocytic proliferative disorder that occurs predominantly in children and young adults. Orbital involvement can occur in 11% of cases. Isolated lacrimal gland involvement without any local or systemic recurrence is very rare. Read More

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December 2018

Large drusen in long-standing retinal detachment.

Oman J Ophthalmol 2018 Sep-Dec;11(3):272-273

Department of Ocular Pathology and Uveitis, Sankara Nethralaya, Chennai, Tamil Nadu, India.

Drusen are seen as an end result of various biochemical insults to the retina and have been described in various clinical settings. We would like to report the histopathology of a case of large drusen, seen associated with chronic retinal detachment in a case of childhood trauma, where the eye was eviscerated for other reasons. Read More

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December 2018

The epidemiology of nonviral microbial keratitis in a tertiary care center in Muscat, Oman.

Oman J Ophthalmol 2018 Sep-Dec;11(3):213-219

Department of Ophthalmology, Al-Nahdah Hospital, Muscat, Oman.

Objective: The objective of this study is to describe the epidemiology, risk factors, etiology, and outcome of microbial keratitis in a tertiary care center in Muscat, Oman.

Methods: The electronic records of all patients diagnosed with keratitis or corneal ulcer between January 2013 and January 2016 in Al-Nahdha Hospital were retrospectively reviewed. Patients who presented with a corneal ulcer requiring admission and who underwent culture and sensitivity studies were included in the study. Read More

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December 2018

Efficacy of rebamipide 2% ophthalmic solution in the treatment of dry eyes.

Oman J Ophthalmol 2018 Sep-Dec;11(3):207-212

Department of Ophthalmology, Mahatma Gandhi Mission's Medical College and Hospital, Navi Mumbai, Maharashtra, India.

Aim: The aim of this study is to evaluate the efficacy of 2% rebamipide ophthalmic solution on the tear functions and ocular surface status in patients with dry eyes.

Materials And Methods: A prospective study was carried out on forty eyes of patients having signs and symptoms of dry eye. Two percent rebamipide ophthalmic solution was applied four times a day for a period of 4 weeks. Read More

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December 2018
3 Reads

A Retrospective Observational Study of Uveitis in a Single Center in Poland with a Review of Findings in Europe.

Med Sci Monit 2018 Dec 3;24:8734-8749. Epub 2018 Dec 3.

Department of Ophthalmology, Medical University of Warsaw, Warsaw, Poland.

BACKGROUND This study aimed to review the causes, presentation, and clinicopathological associations of uveitis in a single department of ophthalmology in Poland, and to compare the findings with previously published studies from other European countries. MATERIAL AND METHODS Review of local patient records between 2005-2015 identified patients diagnosed with uveitis. Data obtained included age, gender, imaging findings, and laboratory diagnostic findings. Read More

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December 2018
2 Reads

Associated Injuries Are Frequent and Severe Among Geriatric Patients With Zygomatico-Orbital Fractures.

J Oral Maxillofac Surg 2018 Nov 5. Epub 2018 Nov 5.

Professor, Department of Oral and Maxillofacial Diseases, Institute of Dentistry, University of Turku and Turku University Hospital, Turku, Finland.

Purpose: Associated injuries (AIs) are hypothesized to be frequent in geriatric zygomatico-orbital (ZMO) fractures. The study aim was to determine the relation between ZMO fractures and AIs in geriatric patients compared with younger adult patients.

Patients And Methods: A retrospective case-and-control study was carried out on geriatric patients at least 65 years of age (n = 93) and younger adult patients 20 to 30 years of age (n = 68) diagnosed with pure unilateral ZMO fractures. Read More

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November 2018

Long-term efficacy and safety profile of multiple injections of intravitreal dexamethasone implant to manage diabetic macular edema: A systematic review of real-world studies.

J Pharmacol Sci 2018 Nov 20. Epub 2018 Nov 20.

Department of Biomedical and Biotechnological Sciences, Section of Pharmacology, University of Catania, Catania, Italy; Center for Research in Ocular Pharmacology, CERFO University of Catania, Catania, Italy; Regional Pharmacovigilance Centre of Catania, A.O.U. Policlinico-Vittorio Emanuele, Catania, Italy.

Introduction: Systematic review of real-world studies about repeated dexamethasone intravitreal implant (DEXi) 0.7 mg in diabetic macular edema management, in order to identify the effective window of time occurring between injections, the critical evaluation of efficacy of the treatment, and the relative long-term safety in the real life setting.

Methods: Literature databases such as PubMed, SCOPUS, and EMBASE were used to identify reports including DEX implant injections. Read More

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November 2018

Multiple orbital cavernous haemangioma of 18 years evolution.

Authors:
R Martins Baia

Arch Soc Esp Oftalmol 2018 Nov 28. Epub 2018 Nov 28.

Departamento de Oftalmología, Escuela de Medicina, Universidad de Montemorelos, Montemorelos, Nuevo León, México; Servicio de Cirugía Plástica Ocular, Vía Lagrimal y Órbita, Departamento de Oftalmología, Instituto de la Visión, Hospital la Carlota, Montemorelos, Nuevo León, México. Electronic address:

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November 2018

Multimodal imaging in a patient with ocular argyrosis complicated by diabetic retinopathy.

Can J Ophthalmol 2018 Dec 24;53(6):e262-e266. Epub 2018 Apr 24.

Sunderland Eye Infirmary, Sunderland, U.K.

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December 2018

Potassium hydroxide as a microscopic evaluation tool for ocular Demodex infestation.

Can J Ophthalmol 2018 Dec 21;53(6):e216-e218. Epub 2018 May 21.

Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan; Institute of Clinical Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan. Electronic address:

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December 2018

Retrobulbar anaesthesia for adjustable strabismus surgery in adults: a prospective observational study.

Can J Ophthalmol 2018 Dec 5;53(6):621-626. Epub 2018 Apr 5.

Department of Ophthalmology, McGill University, Montréal, Qué.

Objective: To characterize the ocular response to retrobulbar anaesthesia and to evaluate the efficacy of retrobulbar anaesthesia for adjustable strabismus surgery in adults.

Design: Prospective observational study.

Participants: Adult patients undergoing adjustable strabismus surgery under retrobulbar anaesthesia. Read More

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December 2018

The effects of the age of onset of strabismus on monocular and binocular visual function in genetically identical twins.

Can J Ophthalmol 2018 Dec 7;53(6):609-613. Epub 2018 Apr 7.

McGill Vision Research, Department of Ophthalmology, McGill University, Montreal, Que. Electronic address:

Objective: Both genetic and environmental factors are thought to play a role in the pathogenesis of strabismus and subsequent ocular dominance and amblyopia. Our purpose was to compare the characteristics of sensory visual function in 2 adult monozygotic (genetically identical) twins who presented with esotropia at different ages.

Methods: Monocular and binocular visual function was measured in the twins. Read More

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December 2018

Iatrogenic limbal stem cell deficiency following drainage surgery for glaucoma.

Can J Ophthalmol 2018 Dec 2;53(6):574-579. Epub 2018 Apr 2.

Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom. Electronic address:

Objective: To describe conjunctival epithelial overgrowth of the cornea after surgery for glaucoma.

Methods: This is a retrospective case series (setting: Moorfields Eye Hospital). Fourteen eyes of 13 patients with suspected limbal stem cell deficiency (LSCD) and corneal conjunctivalization after glaucoma drainage surgery. Read More

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December 2018

Superficial keratectomy: indications and outcomes.

Can J Ophthalmol 2018 Dec 4;53(6):553-559. Epub 2018 Apr 4.

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ont.. Electronic address:

Introduction: To evaluate the indications and outcomes of manual blade superficial keratectomy STUDY DESIGN: Retrospective, nonrandomized, consecutive case series METHODS: Database search of patients from 2012-2017 who underwent superficial keratectomy was conducted at a tertiary care hospital cornea clinic. Charts of 121 patients (156 eyes) were reviewed who had at least 4 weeks of follow-up and both preoperative and postoperative measurements of best-corrected visual acuity or corneal cylinder. Outcome measures included: patient demographics, surgical indication, prior ocular history, best-corrected visual acuity (BCVA) changes, corneal and refractive astigmatism changes, recurrence of pathology, additional treatments required, and intraoperative and postoperative complications. Read More

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December 2018