Biomater Sci 2022 Mar 2;10(5):1281-1291. Epub 2022 Mar 2.
National Engineering Research Centre for Bioengineering Drugs and the Technologies, Institute of Translational Medicine, Nanchang University, Nanchang, Jiangxi, 330088, P.R. China.
Excessive fibrosis is the major factor in the failure of glaucoma filtration surgery. So far, the dominant approach for inhibiting fibrosis is the use of an antimetabolite drug, but the complications it causes, such as filtering bleb leakage, bacterial endophthalmitis and ocular hypotony, are also inevitable. Herein, a multifunctional anti-scarring platform ([email protected]/5-Fu) integrated with outstanding photothermal, antibacterial and drug delivery abilities is developed. Read More