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Arq Neuropsiquiatr 2022 03;80(3):248-254

University College London, Hospitals Biomedical Research Centre, Queen Square Institute of Neurology, London, WC1N 3BG, UK.

Background: The burden of premature mortality associated with human cysticercosis is largely ignored mainly due to poor record-keeping in Taenia solium endemic regions.

Objective: To document mortality and survival characteristics of an historical cohort with cysticercosis.

Methods: The years of onset of symptoms and death untill 1957 were extracted from published reports of a British military cohort (n=450) examined in London in the early twentieth century. Read More

JNMA J Nepal Med Assoc 2021 Oct 15;59(242):1056-1059. Epub 2021 Oct 15.

Department of Vitreoretina, Mechi Eye Hospital, Birtamod, Jhapa, Nepal.

Ocular cysticercosis occurs rarely and may involve various parts of the eye including subretinal space. We report a case of a 42 years-old female with diminution of vision in the right eye for one month and no vision in the left eye for 10 years. Best corrected visual acuity in the right eye was 5/60. Read More

J Family Med Prim Care 2021 Sep 30;10(9):3519-3521. Epub 2021 Sep 30.

Department of Paediatrics, All India Institute of Medical Sciences, Rishikesh, Uttrakhand, India.

Ocular cysticercosis is caused by the larval form of pork tapeworm for which humans and pigs are the intermediate hosts. Intense inflammation secondary to immunological reaction is the hallmark feature of the infection, which can affect almost any tissue of the host. Orbital imaging yields specific features suggestive of the diagnosis. Read More

Cochrane Database Syst Rev 2021 11 1;11:CD009027. Epub 2021 Nov 1.

Department of Neurology, The Walton Centre NHS Foundation Trust, Liverpool, UK.

Background: Neurocysticercosis is the most common parasitic infection of the brain. Epilepsy is the most common clinical presentation, though people may also present with headache, symptoms of raised intracranial pressure, hydrocephalus, and ocular symptoms depending upon the localisation of the parasitic cysts. Anthelmintic drugs, antiepileptic drugs (AEDs), and anti-oedema drugs, such as steroids, form the mainstay of treatment. Read More

Cureus 2021 Sep 24;13(9):e18242. Epub 2021 Sep 24.

Radiology, Dr. D.Y. Patil Medical College, Research Centre and Hospital, Pune, IND.

Cysticercosis results in humans when infected with the larval stage of taenia solium which is called cysticercus cellulosae. The target organs usually involved are the brain, eyes, spine, and skeletal muscles. The ocular form of cysticercosis can affect the intra-ocular structures or involve the orbital adnexa. Read More

Case Rep Ophthalmol Med 2021 30;2021:4038691. Epub 2021 Sep 30.

Birat Eye Hospital, Biratnagar, Nepal.

Ocular cysticercosis is a preventable cause of blindness. It is a parasitic infestation caused by Cysticercus cellulosae-which is the larval form of Taenia solium. In 1829, Soemmering reported the first case of a live anterior chamber cysticercosis. Read More

Surv Ophthalmol 2022 Mar-Apr;67(2):544-569. Epub 2021 Jul 30.

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, RPC-1, AIIMS, New Delhi, India.

Cysticercosis is caused by Taenia solium, a cestode or tapeworm that preferentially affects the subcutaneous tissue, brain, muscle, and the eye. It is traditionally a disease of low socioeconomic regions, but large-scale population migration has made it a matter of global concern. Its ocular invasion is a potentially blinding disease. Read More

Korean J Parasitol 2021 Jun 21;59(3):189-225. Epub 2021 Jun 21.

Department of Environmental Medical Biology, Chung-Ang University College of Medicine, Seoul 06974, Korea.

The use of albendazole and mebendazole, i.e., benzimidazole broad-spectrum anthelmintics, in treatment of parasitic infections, as well as cancers, is briefly reviewed. Read More

Oman J Ophthalmol 2021 Jan-Apr;14(1):8-13. Epub 2021 Feb 27.

Department of Ophthalmology, College of Medicine and Health Sciences, Sultan Qaboos University, Sultan Qaboos University Hospital, Muscat, Oman.

Background: Ocular cysticercosis (OC) is common in tropical countries. This study aimed to analyze the clinical presentation patterns, management and treatment outcomes of OC cases seen at a teaching hospital in North India.

Methods: This study took place between March 2014 and February 2019. Read More

Orbit 2021 10 31;40(5):452. Epub 2021 May 31.

Department of Oculoplasty and Ocular Oncology, Dr Shroff's Charity Eye Hospital, New Delhi, India.

Nepal J Ophthalmol 2021 Jan;13(25):141-145

Nirwana Netralaya, Athkhambhwa, Sasaram- 821115, Bihar, India.

Ocular cysticercosis is a preventable cause of blindness. Medical therapy has been recommended for the retro-orbital and extraocular muscle form. Surgical management is largely done in cases with conjunctival or lid affliction. Read More

Orbit 2021 Oct 27;40(5):400-406. Epub 2020 Oct 27.

Orbit, Oculoplasty, Reconstructive & Aesthetic Services, Sankara Nethralaya, Medical Research Foundation, Chennai, India.

Aim: To describe the clinical and radiological features of orbital cysticercosis and its management outcome.

Material And Method: A retrospective analysis of consecutive cases of orbital cysticercosis between January 2008 and January 2018. The management outcome was classified into good, fair, and poor depending upon the resolution of the clinical features and status of the cyst and scolex in the imaging studies. Read More

Indian J Ophthalmol 2020 Sep;68(9):1999-2001

Department of Ophthalmology, All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, India.

Ocular manifestations due to cysticercosis may involve the vitreous cavity or subretinal space in the posterior segment of the eye. Management of subretinal cysticercosis is challenging, especially if it involves the submacular region. Removal of submacular cysticercosis (SMC) requires utmost care and competent expertise. Read More

Trends Parasitol 2020 10 17;36(10):826-834. Epub 2020 Aug 17.

Instituto de Investigaciones Biomédicas, Unidad de Neuroinflamación, Universidad Nacional Autonoma de México, Ciudad de México, México; Instituto Nacional de Neurología y Neurocirugía, Clínica de Neurocisticercosis, Ciudad de México, México. Electronic address:

The presentation of cysticercosis is very heterogeneous both between and within countries. Several host and parasite factors are involved in this heterogeneity. Differences in the intensity of infection pressure have not been studied thus far. Read More

Nepal J Ophthalmol 2020 Jan;12(23):125-132

Biratnagar Eye Hospital, Biratnagar, Nepal.

Introduction: Ocular cysticercosis is a preventable cause of blindness. It is caused by parasitic infestation caused by the larval form of Taenia solium. Poor sanitation and improper management of food and meat products are the major causes for cysticercosis infestation. Read More

BMC Infect Dis 2020 Mar 14;20(1):220. Epub 2020 Mar 14.

Department of Neurology, King George's Medical University, U.P, Lucknow, 226003, India.

Background: The management of disseminated cysticercosis is unclear and largely considered hazardous. The role of albendazole remains controversial in such patients.

Methods: A tertiary care, University hospital-based prospective intervention study was conducted from December 2015 to December 2017. Read More

Middle East Afr J Ophthalmol 2019 Apr-Jun;26(2):114-116. Epub 2019 Aug 26.

Harare Eye, Ear, Nose and Throat Institute, Harare, Zimbabwe.

Cysticercosis is a parasitic infection caused by the larvae of the cestode . Ocular parasitosis in humans is well recognized; however, cysticercosis of the optic nerve is rare. Here, we report a case of an adult male who presented with right-sided headache and a gradual loss of vision in the right eye. Read More

J Med Case Rep 2019 Sep 18;13(1):295. Epub 2019 Sep 18.

Department of Orthopedics, Nepal Police Hospital, Panipokhari, Kathmandu, Nepal.

Background: Ocular cysticercosis is a disease which rarely involves cutaneous skin and the optic nerve. Patients with clinical presentation of subcutaneous nodules and papilledema should always be evaluated for cysticercosis.

Case Presentation: We report a rare case of ocular cysticercosis with multiple disseminated subcutaneous nodules and papilledema in both eyes. Read More

Int J Parasitol Parasites Wildl 2019 Aug 11;9:342-358. Epub 2019 Apr 11.

Institute of Parasitology, University of Zürich, 8057, Zürich, Switzerland.

Wild mustelids and canids are definitive hosts of and spp. while rodents act as natural intermediate hosts. Rarely, larval stages of these parasites can cause serious zoonoses. Read More

BMC Infect Dis 2019 Jun 20;19(1):543. Epub 2019 Jun 20.

Beijing Institute of Tropical Medicine, Beijing Friendship Hospital, Capital Medical University; Beijing Key Laboratory for Research on Prevention and Treatment of Tropical Diseases, Beijing, China.

Background: Cysticercosis is an emerging and neglected tropical disease (NTD) that poses a serious public health concern worldwide. Disseminated cysticercosis (DCC) is an uncommon manifestation of cysticercosis, also found in China.

Case Presentation: We report three cases of DCC in patients living in China, with different clinical and radiological presentations. Read More

Eur J Ophthalmol 2020 Sep 7;30(5):NP58-NP61. Epub 2019 Apr 7.

Vitreo-Retina, Trauma and Uvea Services, All India Institute of Medical Sciences, New Delhi, India.

Ocular cysticercosis could involve subconjunctival space, anterior chamber, extraocular muscle, subretinal space, or vitreous. The presence of intraocular live cyst is a potential threat to visual acuity. The removal of the cyst in-toto is thus of importance to prevent inflammatory reaction and ocular damage. Read More

Ophthalmic Plast Reconstr Surg 2019 Nov/Dec;35(6):e160

Ophthalmic Plastic Surgery Service, LV Prasad Eye Institute, Bhubaneswar, Odisha, India.

Eur J Case Rep Intern Med 2018 31;5(1):000762. Epub 2018 Jan 31.

Infectious Diseases Department, Hospital de Santa Maria, Lisbon, Portugal.

Cysticercosis is triggered by infection with the larval form of the tapeworm . The usual sites for the development of cyscticerci are the central nervous system (neurocysticercosis - NCC), subcutaneous tissue, skeletal muscle, heart muscle, and the eye. Ocular cysticercosis is caused by the growth of the larvae within ocular tissues. Read More

J Ophthalmic Vis Res 2018 Oct-Dec;13(4):508-510

ICARE Eye Hospital and Postgraduate Institute, Noida, Uttar Pradesh, India.

Purpose: To describe an unusual presentation of ocular cysticercosis and highlight the role of imaging in diagnosis.

Case Report: A 33-year-old female presented with loss of vision in her right eye and features suggesting optic neuritis. Magnetic resonance imaging (MRI) of the brain and orbits revealed a cystic lesion with peripheral rim enhancement in the optic nerve substance at the orbital apex. Read More

Parasitol Res 2018 Dec 13;117(12):3781-3790. Epub 2018 Sep 13.

Universidade Federal do Rio de Janeiro, Instituto de Microbiologia Paulo de Góes, Av. Carlos Chagas Filho, Rio de Janeiro, RJ, 373, Brazil.

The taeniasis/cysticercosis complex is a zoonosis caused by the presence of the parasite Taenia solium in humans. It is considered a neglected disease that causes serious public health and economic problems in developing countries. In humans, the most common locations for the larval form are the skeletal muscles, ocular system, and the central nervous system, which is the most clinically important. Read More

World J Emerg Med 2018 ;9(4):272-275

Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi 110029, India.

Background: The purpose of this study is to assess the utility of ocular ultrasound B scan in the emergency at the first point of care for detecting posterior segment and orbital pathologies in cases of paediatric ocular emergencies.

Methods: A prospective observational study involving 122 paediatric patients presenting to eye emergency over a period of ninety days were assessed with ultrasonography for the posterior segment as well as orbital pathology whenever indicated. The ocular ultrasound was performed gently over closed eyelids. Read More

J Coll Physicians Surg Pak 2018 Aug;28(8):654-655

Department of Paediatrics, Torbay Hospital, Torquay, UK.

Oman J Ophthalmol 2018 May-Aug;11(2):134-139

Ocular Oncology Service, The Operation Eyesight Universal Institute for Eye Cancer, L V Prasad Eye Institute, Hyderabad, Telangana, India.

Background: Langerhans cell histiocytosis (LCH) of the orbit is a rare clinical entity with a diagnostic and therapeutic dilemma.

Materials And Methods: This was a retrospective study of eight patients with orbital LCH.

Results: All eight patients in our series were male, and the mean age at presentation was 8 years (median 6 years; range, 7 months-23 years). Read More

BMJ Case Rep 2018 Jun 8;2018. Epub 2018 Jun 8.

Department of Ophthalmology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, AIIMS, New Delhi, India.

A young male patient presented to our ocular emergency department with chief complaints of progressive pain, redness, diplopia and a right-sided face turn. Ocular examination revealed severely restricted extraocular movements along with retinal folds in the left eye. Initial orbital ultrasound and CT findings were equivocal; however, serology favoured an infective cause. Read More

Int Ophthalmol 2019 May 26;39(5):1151-1154. Epub 2018 Mar 26.

Jasti V Ramanamma Children's Eye Care Centre, L V Prasad Eye Institute, L V Prasad Marg, Banjara Hills, Hyderabad, Telangana, 500034, India.

A 22-year-old male presented to us with complaints of sudden painful loss of vision in left eye 10 days ago along with inward deviation of the left eye. Best-corrected visual acuity (BCVA) in right eye was 20/20 and 20/50 in left eye. Left eye showed limitation of abduction, a relative afferent pupillary defect, normal anterior segment with optic disc oedema. Read More