BMC Med Inform Decis Mak 2017 Apr 14;17(1):42. Epub 2017 Apr 14.
Department of Biotechnology, Chemistry and Pharmacy, University of Siena, Siena, Italy.
Background: Alkaptonuria (AKU; OMIM:203500) is a classic Mendelian genetic disorder described by Garrod already in 1902. It causes urine to turn black upon exposure to air and also leads to ochronosis as well as early osteoarthritis. Our objective is the implementation of a Precision Medicine (PM) approach to AKU. Read More