4,046 results match your criteria Occupational and Environmental Medicine[Journal]


Lifetime exposure to rubber dusts, fumes and N-nitrosamines and cancer mortality in a cohort of British rubber workers with 49 years follow-up.

Occup Environ Med 2019 Feb 16. Epub 2019 Feb 16.

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

Objectives: To quantitatively evaluate exposure-response associations between occupational exposures to rubber dust, fumes and N-nitrosamines and cancer mortality in the UK rubber industry.

Methods: Competing risk survival analyses were used to examine cancer mortality risk in a cohort of 36 441 males aged 35+ years employed in the British rubber industry in 1967, followed up to 2015 (94% mortality). Exposure measurements are based on a population-specific quantitative job-exposure matrix for rubber dust, rubber fumes and N-nitrosamines from the EU-EXASRUB project. Read More

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http://dx.doi.org/10.1136/oemed-2018-105181DOI Listing
February 2019

Job-exposure matrix for historical exposures to rubber dust, rubber fumes and n-Nitrosamines in the British rubber industry.

Occup Environ Med 2019 Feb 16. Epub 2019 Feb 16.

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

Objectives: To develop a quantitative historical job-exposure matrix (JEM) for rubber dust, rubber fumes and n-Nitrosamines in the British rubber industry for 1915-2002 to estimate lifetime cumulative exposure (LCE) for a cohort of workers with 49 years follow-up.

Methods: Data from the EU-EXASRUB database-rubber dust (n=4157), rubber fumes (n=3803) and n-Nitrosamines (n=10 115) collected between 1977 and 2002-were modelled using linear mixed-effects models. Sample year, stationary/personal measurement, industry sector and measurement source were included as fixed explanatory variables and factory as random intercept. Read More

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http://dx.doi.org/10.1136/oemed-2018-105182DOI Listing
February 2019

Farming tasks and the development of rheumatoid arthritis in the agricultural health study.

Occup Environ Med 2019 Feb 13. Epub 2019 Feb 13.

Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.

Objectives: Farming has been associated with rheumatoid arthritis (RA). Some studies have evaluated the effects of pesticides, but other agricultural exposures may also affect immune response.

Methods: We investigated non-pesticide agricultural exposures in relation to RA in licensed pesticide applicators (n=27 175, mostly male farmers) and their spouses (n=22 231) in the Agricultural Health Study (AHS) cohort (1993-1997) who completed at least one follow-up survey through 2015. Read More

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http://dx.doi.org/10.1136/oemed-2018-105361DOI Listing
February 2019

Case-control investigation of occupational lead exposure and kidney cancer.

Occup Environ Med 2019 Feb 13. Epub 2019 Feb 13.

Occupational and Environmental Epidemiology Branch, Division of Cancer Epidemiology Genetics, National Cancer Institute, Bethesda, Maryland, USA.

Objectives: Lead is a suspected carcinogen that has been inconsistently associated with kidney cancer. To clarify this relationship, we conducted an analysis of occupational lead exposure within a population-based study of kidney cancer using detailed exposure assessment methods.

Methods: Study participants (1217 cases and 1235 controls), enrolled between 2002 and 2007, provided information on their occupational histories and, for selected lead-related occupations, answered questions regarding workplace tasks, and use of protective equipment. Read More

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http://dx.doi.org/10.1136/oemed-2018-105327DOI Listing
February 2019

Population-based study of amyotrophic lateral sclerosis and occupational lead exposure in Denmark.

Occup Environ Med 2019 Jan 31. Epub 2019 Jan 31.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

Objectives: Previous research has indicated links between lead (Pb) exposure and increased risk of neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS). In this study, we evaluated the association between occupational Pb exposures and ALS.

Methods: ALS cases were ascertained through the Danish National Patient Registry from 1982 to 2013 and age and sex-matched to 100 controls. Read More

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http://dx.doi.org/10.1136/oemed-2018-105469DOI Listing
January 2019
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The CONSTANCES job exposure matrix based on self-reported exposure to physical risk factors: development and evaluation.

Occup Environ Med 2019 Jan 31. Epub 2019 Jan 31.

Division of General Medical Sciences, Washington University School of Medicine in St. Louis, St. Louis, Missouri, USA.

Objectives: Job exposure matrices (JEMs) can be constructed from expert-rated assessments, direct measurement and self-reports. This paper describes the construction of a general population JEM based on self-reported physical exposures, its ability to create homogeneous exposure groups (HEG) and the use of different exposure metrics to express job-level estimates.

Methods: The JEM was constructed from physical exposure data obtained from the Cohorte des consultants des Centres d'examens de santé (CONSTANCES). Read More

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http://dx.doi.org/10.1136/oemed-2018-105287DOI Listing
January 2019

Occupational exposures and incidence of chronic bronchitis and related symptoms over two decades: the European Community Respiratory Health Survey.

Occup Environ Med 2019 Jan 30. Epub 2019 Jan 30.

Barcelona Institute of Global Health (ISGlobal), Barcelona, Spain.

Objectives: Chronic bronchitis (CB) is an important chronic obstructive pulmonary disease (COPD)-related phenotype, with distinct clinical features and prognostic implications. Occupational exposures have been previously associated with increased risk of CB but few studies have examined this association prospectively using objective exposure assessment. We examined the effect of occupational exposures on CB incidence in the European Community Respiratory Health Survey. Read More

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http://dx.doi.org/10.1136/oemed-2018-105274DOI Listing
January 2019
1 Read

Health and productivity at work: which active workstation for which benefits: a systematic review.

Occup Environ Med 2019 Jan 28. Epub 2019 Jan 28.

École de kinésiologie et des sciences de l'activité physique, Université de Montréal, Montreal, Quebec, Canada.

In order to reduce sedentary behaviour at work, research has examined the effectiveness of active workstations. However, despite their relevance in replacing conventional desks, the comparison between types of active workstations and their respective benefits remains unclear. The purpose of this review article is thus to compare the benefits between standing, treadmill and cycling workstations. Read More

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http://dx.doi.org/10.1136/oemed-2018-105397DOI Listing
January 2019

Exposure to noise and ototoxic chemicals in the Australian workforce.

Occup Environ Med 2019 Jan 25. Epub 2019 Jan 25.

School of Public Health, Curtin University, Perth, Western Australia, Australia.

Objective: To determine the current prevalence of exposure to workplace noise and ototoxic chemicals, including co-exposures.

Method: A cross-sectional telephone survey of nearly 5000 Australian workers was conducted using the web-based application, OccIDEAS. Participants were asked about workplace tasks they performed and predefined algorithms automatically assessed worker's likelihood of exposure to 10 known ototoxic chemicals as well as estimated their full shift noise exposure level (L) of their most recent working day. Read More

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http://dx.doi.org/10.1136/oemed-2018-105471DOI Listing
January 2019

Working conditions and absence from work during pregnancy in a cohort of healthcare workers.

Occup Environ Med 2019 Jan 23. Epub 2019 Jan 23.

Center for Research in Occupational Health, IMIM - Hospital del Mar Medical Research Institute, University Pompeu Fabra, Barcelona, Spain.

Objectives: To assess the relationship between exposure to occupational risk factors during pregnancy and absence from work using two different social benefits.

Method: Three working pregnancy trajectories (WPT) were identified in a cohort of 428 pregnant workers from a healthcare institution (period 2010-2014), based on absence days and using cluster analysis. WPT1 included absences mainly covered by sickness absence benefit (32. Read More

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http://dx.doi.org/10.1136/oemed-2018-105369DOI Listing
January 2019
9 Reads

Functional variant of the carboxypeptidase M (CPM) gene may affect silica-related pneumoconiosis susceptibility by its expression: a multistage case-control study.

Occup Environ Med 2019 Mar 23;76(3):169-174. Epub 2019 Jan 23.

Jiangsu Provincial Key Laboratory of Geriatrics, Department of Geriatrics, The First Affiliated Hospital with Nanjing Medical University, Nanjing, China.

Objectives: In a genome-wide association study, we discovered chromosome 12q15 (defined as rs73329476) as a silica-related pneumoconiosis susceptibility region. However, the causal variants in this region have not yet been reported.

Methods: We systematically screened eight potentially functional single-neucleotide polymorphism (SNPs) in the genes near rs73329476 (carboxypeptidase M () and cleavage and polyadenylation specific factor 6 ()) in a case-control study including 177 cases with silicosis and 204 healthy controls, matched to cases with years of silica dust exposure. Read More

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http://dx.doi.org/10.1136/oemed-2018-105545DOI Listing
March 2019
1 Read
3.267 Impact Factor

Mortality and cancer incidence among female Australian firefighters.

Occup Environ Med 2019 Jan 23. Epub 2019 Jan 23.

Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.

Objectives: To investigate the mortality and cancer incidence of female firefighters, a group where there are limited published findings.

Methods: Participating fire agencies supplied records of individual firefighters including the number and type of incidents attended. The cohort was linked to the Australian National Death Index and Australian Cancer Database. Read More

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http://dx.doi.org/10.1136/oemed-2018-105336DOI Listing
January 2019

Changes in common mental disorders and diagnosis-specific sickness absence: a register-linkage follow-up study among Finnish municipal employees.

Occup Environ Med 2019 Jan 23. Epub 2019 Jan 23.

Department of Public Health, University of Helsinki, Helsinki, Finland.

Objective: This study examined the associations between changes in common mental disorders (CMD) and subsequent diagnosis-specific sickness absence (SA) among midlife and ageing municipal employees.

Methods: Data from the Helsinki Health Study phase I (2000-2002) and phase II (2007) surveys among employees of the City of Helsinki, Finland, were linked with prospective register data from the Social Insurance Institution of Finland on diagnosis-specific (mental, musculoskeletal, other causes) SA (n=3890). Associations between change in CMD (General Health Questionnaire 12) from phase I to phase II and the first SA event in 2007-2014 were analysed using Cox regression modelling. Read More

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http://dx.doi.org/10.1136/oemed-2018-105423DOI Listing
January 2019

Identifying occupationally exposed populations for lung cancer screening: it is about time.

Authors:
Fraser Brims

Occup Environ Med 2019 Mar 19;76(3):135-136. Epub 2019 Jan 19.

Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.

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http://dx.doi.org/10.1136/oemed-2018-105464DOI Listing

ECG conduction disturbances and ryanodine receptor expression levels in occupational lead exposure workers.

Occup Environ Med 2019 Mar 19;76(3):151-156. Epub 2019 Jan 19.

Department of Occupational Health and Toxicology, School of Public Health, Nanchang University, Nanchang, China.

Objectives: A significant number of researches have evidenced that occupational lead (Pb) exposure increased risks of cardiovascular disease. However, evidences about the potential effects of Pb on the cardiac conduction system are sparse and inconclusive. Besides, ryanodine receptors (RyRs) induced dysfunction of cardiac excitation contraction coupling which is considered to be one of the mechanisms in cardiovascular diseases. Read More

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http://dx.doi.org/10.1136/oemed-2018-105463DOI Listing
March 2019
3 Reads

Bone lead associations with blood lead, kidney function and blood pressure among US, lead-exposed workers in a surveillance programme.

Occup Environ Med 2019 Jan 19. Epub 2019 Jan 19.

Department of Environmental Health, Rollins School of Public Health at Emory University, Atlanta, Georgia, USA.

Objectives: Bone lead and past blood lead levels may be more strongly associated with current health effects than current blood lead, representing recent exposure. We examined whether current bone lead was correlated with maximum past blood lead and compared how three lead measures predicted current blood pressure (BP) and kidney function among workers with past occupational lead exposure.

Methods: Adult men in a lead surveillance programme residing near New York City were enrolled. Read More

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http://dx.doi.org/10.1136/oemed-2018-105505DOI Listing
January 2019

Night work and sick leave during pregnancy: a national register-based within-worker cohort study.

Occup Environ Med 2019 Mar 19;76(3):163-168. Epub 2019 Jan 19.

Department of Occupational and Environmental Medicine, Bispebjerg and Frederiksberg University Hospital, Copenhagen, Denmark.

Objective: The aim of our study was to investigate the acute effect of night work during pregnancy on the risk of calling in sick the following day using register-based information and the workers as their own controls.

Methods: Using the payroll-based national Danish Working Hour Database, including all public hospital employees in Denmark, we identified 9799 pregnant women with ≥1 day shift and ≥1 night shift and ≥1 day of sick leave during the first 32 pregnancy weeks from January 2007 to December 2013. We performed fixed effects logistic regression, that is, within-worker comparisons, of the risk of sick leave of any duration starting within 24 hours after night shifts of different length versus day shifts. Read More

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http://dx.doi.org/10.1136/oemed-2018-105331DOI Listing

Pyromellitic dianhydride (PMDA) may cause occupational asthma.

Occup Environ Med 2019 Mar 11;76(3):175-177. Epub 2019 Jan 11.

Department of Occupational and Environmental Medicine, Odense University Hospital, Odense, Denmark.

Introduction: Anhydrides are widely used as cross-linking agents in epoxy resins and alkyd production, for example, as coatings and adhesives in plastic products. Sensitisation to several anhydrides is known to cause occupational asthma. There are indications that the lesser known pyromellitic dianhydride (PMDA) can cause irritative respiratory symptoms and possibly asthma. Read More

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http://oem.bmj.com/lookup/doi/10.1136/oemed-2018-105295
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http://dx.doi.org/10.1136/oemed-2018-105295DOI Listing
March 2019
4 Reads

Work-focused interventions that promote the labour market transition of young adults with chronic disabling health conditions: a systematic review.

Occup Environ Med 2019 Mar 11;76(3):189-198. Epub 2019 Jan 11.

School of Health and Exercise Sciences, University of British Columbia, Kelowna, British Columbia, Canada.

Objective: Young adulthood is an important transitional life phase where careers are established. Young adults with chronic disabling health conditions are underrepresented in the labour market. Our study aims to examine the effectiveness of work-focused interventions that support the labour market transition of young adults with chronic disabling health conditions; and to examine whether the effectiveness of work-focused interventions differ across work transition phase (eg, preparation, entry and sustaining work, employment advancement) and disability type. Read More

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http://oem.bmj.com/lookup/doi/10.1136/oemed-2018-105454
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http://dx.doi.org/10.1136/oemed-2018-105454DOI Listing
March 2019
4 Reads

Work-unit organisational changes and subsequent prescriptions for psychotropic medication: a longitudinal study among public healthcare employees.

Occup Environ Med 2019 Mar 7;76(3):143-150. Epub 2019 Jan 7.

Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

Objectives: We examined exposure to different types of organisational changes at work as risk factors for subsequent prescription for psychotropic medication among employees.

Methods: The study population included 15 038 public healthcare employees nested within 1284 work units in the Capital Region of Denmark. Multilevel mixed-effects parametric survival models were developed to examine time to prescription for psychotropic medications (anxiolytics/hypnotics/sedatives/antidepressants) during the 12-month interval following exposure to organisational changes relative to no change from January to December 2013. Read More

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http://dx.doi.org/10.1136/oemed-2018-105442DOI Listing

A nationwide follow-up study of occupational organic dust exposure and risk of chronic obstructive pulmonary disease (COPD).

Occup Environ Med 2019 Feb 31;76(2):105-113. Epub 2018 Dec 31.

Department of Public Health, Section of Environment, Occupation and Health, Danish Ramazzini Centre, Aarhus University, Aarhus, Denmark.

Objectives: To study exposure-response relations between cumulative organic dust exposure and incident chronic obstructive pulmonary disease (COPD) among subjects employed in the Danish farming and wood industry.

Methods: We studied exposure-response relations between cumulative organic dust exposure and incident COPD (1997-2013) among individuals born during 1950-1977 in Denmark ever employed in the farming or wood industry (n=1 75 409). Industry-specific employment history (1964-2007), combined with time-dependent farming and wood industry-specific exposure matrices defined cumulative exposure. Read More

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http://dx.doi.org/10.1136/oemed-2018-105323DOI Listing
February 2019

Resilience-based intervention for UK military recruits: a randomised controlled trial.

Occup Environ Med 2019 Feb 18;76(2):90-96. Epub 2018 Dec 18.

Academic Department of Military Mental Health, King's College London, London, UK.

Objectives: We evaluated a military resilience intervention which aimed to help UK military recruits to manage their personal health and well-being more effectively.

Methods: Trainers within six pre-existing training teams were randomly allocated by team to deliver a resilience-based intervention (SPEAR) or usual training (control) during recruit training. 23 trainers delivered SPEAR; 18 delivered the control training. Read More

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http://dx.doi.org/10.1136/oemed-2018-105503DOI Listing
February 2019

Occupational cannabis exposure and allergy risks.

Occup Environ Med 2019 Feb 15;76(2):78-82. Epub 2018 Dec 15.

Department of Immunology-Allergology-Rheumatology, University of Antwerp, Antwerp (Belgium) and Antwerp University Hospital, Antwerp, Belgium.

Objectives: Cannabis allergy has mainly been described following recreational use but some cases also point to cannabis sensitisation as a result of occupational exposure. As a consequence, little is known on the prevalence and clinical phenotype of occupational cannabis allergy. Therefore, this study aims to explore the allergy-associated health risks of occupational cannabis exposure in Belgian police force personnel. Read More

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http://dx.doi.org/10.1136/oemed-2018-105302DOI Listing
February 2019
2 Reads

Women's occupational exposure to polycyclic aromatic hydrocarbons and risk of breast cancer.

Occup Environ Med 2019 Jan;76(1):22-29

Population Oncology, BC Cancer, Vancouver, British Columbia, Canada.

Objective: To estimate the association between occupational polycyclic aromatic hydrocarbon (PAH) exposure and female breast cancer.

Methods: Lifetime work histories for 1130 cases and 1169 controls from British Columbia and Ontario (Canada) were assessed for PAH exposure using a job-exposure matrix based on compliance measurements obtained during US Occupational Safety and Health Administration workplace safety inspections.

Results: Exposure to any level of PAHs was associated with an increased risk of breast cancer (OR=1. Read More

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http://dx.doi.org/10.1136/oemed-2018-105261DOI Listing
January 2019

Tunnel driving occupational environment and hearing loss in train drivers in China.

Occup Environ Med 2019 Feb 11;76(2):97-104. Epub 2018 Dec 11.

Locomotive Department, China Railway Guangzhou Group, Guangzhou, China.

Objective: Hearing loss caused by high levels of noise is a potential occupational health disorder among train drivers around the world. This study aims to investigate the relationship between tunnel driving occupational environment and hearing loss in train drivers, to provide some insights into helping reduce hearing loss among train drivers.

Methods: This study analysed cross-sectional data for 1214 train drivers who work at China Railway Guangzhou Group. Read More

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http://dx.doi.org/10.1136/oemed-2018-105269DOI Listing
February 2019
3.267 Impact Factor

Artificial stone-associated silicosis in Belgium: response.

Occup Environ Med 2019 Feb 11;76(2):134. Epub 2018 Dec 11.

Thoracic Medicine, St Vincent's Hospital, Sydney, New South Wales, Australia.

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http://oem.bmj.com/lookup/doi/10.1136/oemed-2018-105563
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http://dx.doi.org/10.1136/oemed-2018-105563DOI Listing
February 2019
3 Reads

Usual adult occupation and risk of prostate cancer in West African men: the Ghana Prostate Study.

Occup Environ Med 2019 Feb 7;76(2):71-77. Epub 2018 Dec 7.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland, USA.

Objectives: Established prostate cancer (PCa) risk factors include age, family history of PCa and African ancestry. Studies, mostly among highly screened, predominantly European ancestral populations, suggest that employment in certain occupations (eg, farming, military) may also have an increased risk for PCa. Here, we evaluated the association between usual adult occupation and PCa risk in Ghanaian men, a population with historically low rates of PCa screening. Read More

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http://dx.doi.org/10.1136/oemed-2018-105391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335162PMC
February 2019

Multiorgan accelerated silicosis misdiagnosed as sarcoidosis in two workers exposed to quartz conglomerate dust.

Occup Environ Med 2019 Mar 4;76(3):178-180. Epub 2018 Dec 4.

Department of Cardiologic, Thoracic and Vascular Sciences, University of Padova, Padova, Italy.

Introduction: Clusters of silicosis cases have been reported in the fabrication of quartz conglomerate, a new high-silica-content artificial stone for kitchen and bathroom benchtops (countertops).

Aim: We describe two cases of accelerated-type silicosis with hepatic granulomas arising in workers exposed to artificial quartz conglomerates.

Methods: A confident diagnosis of multiorgan silicosis was based on high level of respirable silica in the workplace, typical radiological alterations in chest high-resolution CT, histological findings in the lung and liver, and detection of silica crystals in both tissues by phase-contrast polarising light microscopy and scanning electron microscopy and energy dispersive spectroscopy. Read More

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http://dx.doi.org/10.1136/oemed-2018-105462DOI Listing
March 2019
4 Reads

Mortality of US astronauts: comparisons with professional athletes.

Occup Environ Med 2019 Feb 4;76(2):114-117. Epub 2018 Dec 4.

Mortality Research & Consulting, City of Industry, California, USA.

Objective: Studies of mortality among US astronauts are complicated by the healthy worker effect, which predicts lower mortality for astronauts than the general population based solely on the ability to become and remain an astronaut. We attempt to evaluate astronaut mortality risk while accounting for the healthy worker effect.

Methods: We compare mortality rates of male US astronauts with those of professional athletes from Major League Baseball and the National Basketball Association between January 1, 1960 and May 31, 2018. Read More

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http://dx.doi.org/10.1136/oemed-2018-105304DOI Listing
February 2019
1 Read

Night shift work and abnormal liver function: is non-alcohol fatty liver a necessary mediator?

Occup Environ Med 2019 Feb 4;76(2):83-89. Epub 2018 Dec 4.

JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China.

Objectives: Accumulated evidence implies that night shift work may trigger liver dysfunction. Non-alcoholic fatty liver (NAFL) is suggested to be a necessary mediator in this process. This study aimed to examine the relationship between night shift work and elevated level of alanine transaminase (e-ALT) of workers and investigate the potential mediation effect of NAFL. Read More

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http://dx.doi.org/10.1136/oemed-2018-105273DOI Listing
February 2019
16 Reads

COPD, airflow limitation and chronic bronchitis in farmers: a systematic review and meta-analysis.

Occup Environ Med 2019 Jan 27;76(1):58-68. Epub 2018 Nov 27.

Service Hospitalier Universitaire Pneumologie Physiologie, Pôle Thorax et Vaisseaux, Grenoble, France.

Introduction: The current definition of chronic obstructive pulmonary disease (COPD) associates persistent airflow limitation and chronic respiratory symptoms. Agricultural work has been associated with an increased risk of developing COPD, but the prevalence and definition of the disease vary greatly between studies. This meta-analysis aimed to assess the association between agricultural work and COPD using the most widely used definitions of the disease. Read More

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http://dx.doi.org/10.1136/oemed-2018-105310DOI Listing
January 2019
1 Read

Patterns and trends in OSHA occupational noise exposure measurements from 1979 to 2013.

Occup Environ Med 2019 Feb 27;76(2):118-124. Epub 2018 Nov 27.

Department of Environmental Health Sciences, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.

Objectives: Noise is one of the most common exposures, and occupational noise-induced hearing loss (NIHL) is highly prevalent. In addition to NIHL, noise is linked to numerous non-auditory health effects. The Occupational Safety and Health Administration (OSHA) maintains the Integrated Management Information System (IMIS) database of compliance-related measurements performed in various industries across the USA. Read More

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http://dx.doi.org/10.1136/oemed-2018-105041DOI Listing
February 2019
1 Read

Bruised apples: violence against women in the education sector.

Occup Environ Med 2019 Jan 21;76(1):1-2. Epub 2018 Nov 21.

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http://dx.doi.org/10.1136/oemed-2018-105426DOI Listing
January 2019

Job-exposure matrices addressing lifestyle factors.

Occup Environ Med 2018 Dec;75(12):847

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http://dx.doi.org/10.1136/oemed-2018-105425DOI Listing
December 2018

Bulky DNA adducts, microRNA profiles, and lipid biomarkers in Norwegian tunnel finishing workers occupationally exposed to diesel exhaust.

Occup Environ Med 2019 Jan 13;76(1):10-16. Epub 2018 Nov 13.

Section for Toxicology and Biological Work Environment, Department of Chemical and Biological Work Environment, National Institute of Occupational Health, Oslo, Norway.

Objectives: This study aimed to assess the biological impact of occupational exposure to diesel exhaust (DE) including DE particles (DEP) from heavy-duty diesel-powered equipment in Norwegian tunnel finishing workers (TFW).

Methods: TFW (n=69) and referents (n=69) were investigated for bulky DNA adducts (by P-postlabelling) and expression of microRNAs (miRNAs) (by small RNA sequencing) in peripheral blood mononuclear cells (PBMC), as well as circulating free arachidonic acid (AA) and eicosanoid profiles in plasma (by liquid chromatography-tandem mass spectrometry).

Results: PBMC from TFW showed significantly higher levels of DNA adducts compared with referents. Read More

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http://oem.bmj.com/lookup/doi/10.1136/oemed-2018-105445
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http://dx.doi.org/10.1136/oemed-2018-105445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327869PMC
January 2019
8 Reads

Epidemiology of silicosis: reports from the SWORD scheme in the UK from 1996 to 2017.

Occup Environ Med 2019 Jan 10;76(1):17-21. Epub 2018 Nov 10.

Centre for Occupational and Environmental Health, University of Manchester, Manchester, UK.

Objective: To document the demographic risk factors of workers reported to have silicosis in the UK.

Methods: All cases of silicosis reported to the Surveillance of Work-related and Occupational Respiratory Disease (SWORD) scheme between January 1996 and December 2017 were classified into one of eight industry categories, and one of five age groups. In addition, to investigate whether there had been any temporal change, mean age and range at diagnosis was plotted for each year. Read More

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http://oem.bmj.com/lookup/doi/10.1136/oemed-2018-105337
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http://dx.doi.org/10.1136/oemed-2018-105337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327866PMC
January 2019
25 Reads

Early detection of lung cancer in a population at high risk due to occupation and smoking.

Occup Environ Med 2019 Mar 10;76(3):137-142. Epub 2018 Nov 10.

Center for Construction Research and Training, Silver Spring, Maryland, USA.

Objective: The US National Comprehensive Cancer Network (NCCN) recommends two pathways for eligibility for Early Lung Cancer Detection (ELCD) programmes. Option 2 includes individuals with occupational exposures to lung carcinogens, in combination with a lesser requirement on smoking. Our objective was to determine if this algorithm resulted in a similar prevalence of lung cancer as has been found using smoking risk alone, and if so to present an approach for lung cancer screening in high-risk worker populations. Read More

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http://oem.bmj.com/lookup/doi/10.1136/oemed-2018-105431
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http://dx.doi.org/10.1136/oemed-2018-105431DOI Listing
March 2019
10 Reads

Artificial stone-associated silicosis in Belgium.

Occup Environ Med 2019 Feb 1;76(2):133-134. Epub 2018 Nov 1.

Clinic of Occupational and Environmental Medicine, University Hospitals Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1136/oemed-2018-105436DOI Listing
February 2019
3 Reads

Urinary 2,5-dicholorophenol and 2,4-dichlorophenol concentrations and prevalent disease among adults in the National Health and Nutrition Examination Survey (NHANES).

Occup Environ Med 2019 Mar 30;76(3):181-188. Epub 2018 Oct 30.

Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA.

Objective: To test cross-sectional associations between urinary concentrations of 2,5-dichlorophenol (2,5-DCP) and 2,4-dichlorophenol (2,4-DCP) with the prevalence of cardiovascular disease (CVD), cancer, lung disease, thyroid problems and liver conditions.

Methods: Logistic regression was used to evaluate associations of urinary concentrations of 2,5-DCP and 2,4-DCP with prevalence of various medical conditions among 3617 National Health and Nutrition Examination Survey participants from 2007-2008 and 2009-2010. ORs and 95% CIs for each disease were estimated. Read More

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http://dx.doi.org/10.1136/oemed-2018-105278DOI Listing

Post-traumatic growth in the military: a systematic review.

Occup Environ Med 2018 Dec 30;75(12):904-915. Epub 2018 Oct 30.

King's Centre for Military Health Research, King's College London, London, UK.

Background: Post-traumatic growth is defined as positive psychological, social or spiritual growth after a trauma.

Objectives: This systematic review aimed to identify studies that quantitatively measured post-traumatic growth among (ex-) military personnel, to determine whether there is evidence of growth in this context and whether such growth is associated with any sociodemographic, military, trauma or mental health factors.

Data Sources: The electronic databases PsycInfo, OVIDmedline and Embase were searched for studies published between 2001 and 2017. Read More

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http://dx.doi.org/10.1136/oemed-2018-105166DOI Listing
December 2018

Ambient concentrations of NO and hospital admissions for schizophrenia.

Occup Environ Med 2019 Feb 26;76(2):125-131. Epub 2018 Oct 26.

Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei, China.

Objectives: Schizophrenia is a chronic and severe mental disorder affecting more than 21 million people worldwide. Short-term exposure to nitrogen dioxide (NO) has been associated with hospital admissions (HAs) for mental disorders, but no study has evaluated the specific association of NO and schizophrenia. Additionally, the shape of the concentration-response (C-R) curve has not yet been assessed at present. Read More

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http://dx.doi.org/10.1136/oemed-2018-105162DOI Listing
February 2019

Daily physical activity patterns among aging workers: the Finnish Retirement and Aging Study (FIREA).

Occup Environ Med 2019 Jan 23;76(1):33-39. Epub 2018 Oct 23.

Department of Public Health, University of Turku, and Turku University Hospital, Turku, Finland.

Objectives: Physical activity is associated with the aging workers' ability to work and predicts working beyond retirement age. To better understand physical activity behaviour in this growing population group, we aimed at characterising 24-hour physical activity patterns among aging workers, and to describe the association between occupational category and total, occupational and leisure-time physical activities.

Methods: We included 878 workers (mean age 62. Read More

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http://dx.doi.org/10.1136/oemed-2018-105266DOI Listing
January 2019

Risk factors for post-9/11 chronic rhinosinusitis in Fire Department of the City of New York workers.

Occup Environ Med 2018 Dec 18;75(12):884-889. Epub 2018 Oct 18.

Pulmonary, Critical Care and Sleep Medicine Division, Departments of Medicine and Environmental Medicine, New York University School of Medicine, New York City, New York, USA.

Objectives: Chronic rhinosinusitis (CRS) has high socioeconomic burden but underexplored risk factors. The collapse of the World Trade Center (WTC) towers on 11 September 2001 (9/11) caused dust and smoke exposure, leading to paranasal sinus inflammation and CRS. We aim to determine which job tasks are risk factors for CRS in WTC-exposed Fire Department of the City of New York (FDNY) firefighters and emergency medical services (EMS) workers. Read More

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http://dx.doi.org/10.1136/oemed-2018-105297DOI Listing
December 2018
2 Reads

Correction: .

Authors:

Occup Environ Med 2018 Nov;75(11):845-846

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http://dx.doi.org/10.1136/oemed-2017-104384corr1DOI Listing
November 2018
1 Read

Multisite musculoskeletal pain trajectories from midlife to old age: a 28-year follow-up of municipal employees.

Occup Environ Med 2018 Dec 15;75(12):863-870. Epub 2018 Oct 15.

Finnish Institute of Occupational Health, Helsinki, Finland.

Objectives: We studied the developmental trajectories of multisite musculoskeletal pain (MSP) to learn whether pain in midlife persists to old age, and whether pain trajectories associate with midlife work or lifestyle exposures or retirement from work.

Methods: Municipal employees aged 44-58 years were studied in 1981 (n=6257) with follow-ups in 1985, 1992, 1997 and 2009. Pain in the neck, low back, and upper and lower limbs was assessed in each survey. Read More

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http://oem.bmj.com/lookup/doi/10.1136/oemed-2018-105235
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http://dx.doi.org/10.1136/oemed-2018-105235DOI Listing
December 2018
3 Reads

Risk of asthma and chronic obstructive pulmonary disease in a large historical cohort of Danish firefighters.

Occup Environ Med 2018 Dec 15;75(12):871-876. Epub 2018 Oct 15.

The Danish Cancer Society Research Center, The Danish Cancer Society, Copenhagen, Denmark.

Objective: Firefighters are exposed to numerous respiratory hazards, but large studies on the risk of pulmonary disease are scarce. The objective of this study was to examine incidence of asthma and chronic obstructive pulmonary disease (COPD) in a nationwide cohort of Danish firefighters.

Methods: We used individual historical employment records on 11 968 Danish male firefighters primarily supplied by trade unions and fire agencies. Read More

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http://oem.bmj.com/lookup/doi/10.1136/oemed-2018-105234
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http://dx.doi.org/10.1136/oemed-2018-105234DOI Listing
December 2018
2 Reads

Job strain and cognitive change: the Baltimore Epidemiologic Catchment Area follow-up study.

Occup Environ Med 2018 Dec 15;75(12):856-862. Epub 2018 Oct 15.

Department of Mental Health, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA.

Objectives: To investigate the association between job strain and subsequent cognitive change over approximately 11 years, using data from the population-based Baltimore Epidemiologic Catchment Area follow-up study.

Methods: The sample ranged from 555 to 563 participants, depending on the outcome, who reported psychosocial characteristics corresponding to the full-time job they held at baseline (1993-1996). Overall cognitive performance was measured by the Mini-Mental State Examination (MMSE), and verbal memory was measured by the ImmediateWord Recall Task and Delayed Word Recall Task at baseline and follow-up (2004-2005). Read More

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http://dx.doi.org/10.1136/oemed-2018-105213DOI Listing
December 2018
12 Reads

Tuberculosis, mining and silica.

Authors:
Rodney I Ehrlich

Occup Environ Med 2018 Nov 8;75(11):763-764. Epub 2018 Oct 8.

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http://dx.doi.org/10.1136/oemed-2018-105318DOI Listing
November 2018
7 Reads

How to improve the assessment of the impact of occupational diseases at a national level? The Netherlands as an example.

Occup Environ Med 2019 Jan 8;76(1):30-32. Epub 2018 Oct 8.

Amsterdam UMC, University of Amsterdam, Department: Coronel Institute of Occupational Health, Netherlands Center for Occupational Diseases, Amsterdam Public Health research institute, Amsterdam, The Netherlands.

Objective: To explore the impact of occupational diseases (ODs) through estimations of population attributable fractions (PAFs) in a national context.

Methods: PAFs were calculated for eight prevalent ODs using existing data on the prevalence of exposure to risk factors at work and the strength of their association with diseases based on systematic reviews. Six systematic reviews with meta-analyses and two overview papers were selected. Read More

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http://oem.bmj.com/lookup/doi/10.1136/oemed-2018-105387
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http://dx.doi.org/10.1136/oemed-2018-105387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327862PMC
January 2019
13 Reads

Recurrent back pain during working life and exit from paid employment: a 28-year follow-up of the Whitehall II Study.

Occup Environ Med 2018 Nov 4;75(11):786-791. Epub 2018 Oct 4.

Population and Work Ability Program, Finnish Institute of Occupational Health, Helsinki, Finland.

Objectives: To examine the impact of recurrent, as compared with single, reports of back pain on exit from paid employment over decades of follow-up.

Methods: The study sample was from the British Whitehall II Study cohort (n=8665, 69% men, aged 35-55 at baseline), who had provided information about their reports of back pain between 1985 and 1994. Data about exit from paid employment (health-related and non-health related exit, unemployment and other exit) were collected between 1995 and 2013. Read More

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http://oem.bmj.com/lookup/doi/10.1136/oemed-2018-105202
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http://dx.doi.org/10.1136/oemed-2018-105202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6227793PMC
November 2018
2 Reads