28,978 results match your criteria Obstructive Sleep Apnea-Hypopnea Syndrome


Effect of Albuterol Premedication vs Placebo on the Occurrence of Respiratory Adverse Events in Children Undergoing Tonsillectomies: The REACT Randomized Clinical Trial.

JAMA Pediatr 2019 Apr 22. Epub 2019 Apr 22.

Telethon Kids Institute, Perth, Australia.

Importance: Tonsillectomy is a common pediatric procedure for the treatment of sleep-disordered breathing and chronic tonsillitis. Up to half of children having this procedure experience a perioperative respiratory adverse event.

Objective: To determine whether inhaled albuterol sulfate (salbutamol sulfate) premedication decreases the risk of perioperative respiratory adverse events in children undergoing anesthesia for tonsillectomy. Read More

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http://dx.doi.org/10.1001/jamapediatrics.2019.0788DOI Listing

Is prone sleeping dangerous for neonates? Polysomnographic characteristics and NDN gene analysis.

Ci Ji Yi Xue Za Zhi 2019 Apr-Jun;31(2):113-117

Department of Pediatrics, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan.

Objective: Prone sleep is an identified risk factor for sudden infant death syndrome, possibly due to reduced blood pressure, cerebral oxygenation, and impaired cerebral vascular control. Cardiac and respiratory responses in neonates during supine and prone sleep have not been reported.

Materials And Methods: In this study, daytime polysomnography (PSG) data from 17 neonates aged 2-3 days during supine and prone sleep were reported and the NDN gene, an important gene for neonatal respiratory control, was sequenced for correlation with neonatal respiratory parameters. Read More

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http://www.tcmjmed.com/text.asp?2019/31/2/113/236553
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http://dx.doi.org/10.4103/tcmj.tcmj_29_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450148PMC
April 2019
1 Read

Investigation of smell and taste function in patients with obstructive sleep apnoea syndrome.

J Laryngol Otol 2019 Apr 22:1-4. Epub 2019 Apr 22.

Department of Otorhinolaryngology,Faculty of Medicine,Bezmialem Vakif University,Istanbul,Turkey.

Objective: This study investigated the relationship between disease severity and taste and smell functions in patients with obstructive sleep apnoea syndrome.

Methods: A total of 65 patients with recurrent upper airway obstruction during sleep were included. Participants were divided into four groups according to apnoea-hypopnoea index, obtained on polysomnography. Read More

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http://dx.doi.org/10.1017/S0022215119000768DOI Listing

Retropharyngeal Tuberculous Abscess: A Rare Cause of Upper Airway Obstruction and Obstructive Sleep Apnea in Children: A Case Report.

J Trop Pediatr 2019 Apr 21. Epub 2019 Apr 21.

Pediatric Pulmonology, Hamburg University, Hamburg, Germany.

Retropharyngeal tuberculous abscess (RPTBA) is a rare manifestation of tuberculosis (TB) even in high TB burden areas. It rarely manifests as a cause of upper airway obstruction and obstructive sleep apnea (OSA) in children with few case reports in the literature. We report a 22 months old toddler who presented with upper airway obstruction and OSA and was diagnosed with RPTBA. Read More

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http://fdslive.oup.com/www.oup.com/pdf/production_in_progres
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http://dx.doi.org/10.1093/tropej/fmz018DOI Listing
April 2019
1 Read

Trends and predictors of recurrent acute coronary syndrome hospitalizations and unplanned revascularization after index acute myocardial infarction treated with percutaneous coronary intervention.

Am Heart J 2019 Mar 5;212:134-143. Epub 2019 Mar 5.

Centre of Cardiovascular Research and Education in Therapeutics (CCRE), Monash University, Melbourne, Australia; Department of Cardiovascular Medicine, Alfred Hospital, Melbourne, Australia. Electronic address:

Background: Repeat hospitalizations for recurrent acute coronary syndrome (ACS) or unplanned revascularization after acute myocardial infarction (MI) are common, costly and potentially preventable. We aim to describe 10-year trends and identify independent risk factors of these repeat hospitalizations.

Methods: We analyzed data from 9615 patients from the Melbourne Interventional Group registry (2005-2014) who underwent percutaneous coronary intervention (PCI) for their index MI and survived to discharge. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00028703193004
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http://dx.doi.org/10.1016/j.ahj.2019.02.013DOI Listing
March 2019
145 Reads

Retinal Vessel Phenotype in Patients with Non-Arteritic Anterior Ischemic Optic Neuropathy.

Am J Ophthalmol 2019 Apr 17. Epub 2019 Apr 17.

Department of ophthalmology, University Hospital of Grenoble-Alpes, France; Grenoble-Alpes University, HP2 Laboratory, INSERM U1042, Grenoble, France; Department of Ophthalmology, University Hospital of Grenoble-Alpes, Grenoble, France. Electronic address:

Purpose: The pathophysiology of non-arteritic AION (N-AION) is not completely understood. Studies of the retinal vasculature phenotype in patients with N-AION could help us to understand vascular abnormalities associated with the disease.

Design: Retrospective case series with matched controls. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00029394193018
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http://dx.doi.org/10.1016/j.ajo.2019.04.007DOI Listing
April 2019
1 Read

Quantitative EEG measures in REM and NREM sleep are associated with AHI and nocturnal hypoxemia in men.

Sleep 2019 Apr 20. Epub 2019 Apr 20.

The Health Observatory, Adelaide Medical School, University of Adelaide, The Queen Elizabeth Hospital Campus, Woodville, South Australia, Australia.

Study Objectives: Quantitative EEG measures of sleep may identify vulnerability to obstructive sleep apnea (OSA) sequelae, however, small clinical studies of sleep microarchitecture in OSA show inconsistent alterations. We examined relationships between quantitative EEG measures during rapid eye movement (REM) and non-REM (NREM) sleep and OSA severity among a large population-based sample of men while accounting for insomnia.

Methods: All-night EEG (F4-M1) recordings from full in-home polysomnography (Embletta X100) in 664 men with no prior OSA diagnosis (age ≥40) were processed following exclusion of artefacts. Read More

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http://dx.doi.org/10.1093/sleep/zsz092DOI Listing

Positive Airway Pressure Therapy Reduces Pulmonary Hypertension in Patients Admitted for Acute Heart Failure with Pulmonary Hypertension and Obstructive Sleep Apnea. The ASAP-HF Pilot Trial.

Sleep 2019 Apr 20. Epub 2019 Apr 20.

Clinic for Cardiology, Herz- und Diabeteszentrum NRW, Ruhr-Universität Bochum, Bad Oeynhausen, Germany.

Pulmonary hypertension(PH) is extremely common in acute decompensated heart failure (ADHF) patients and predicts increased mortality. Obstructive sleep apnea (OSA) is highly prevalent in CHF patients, may contribute to further elevated pulmonary pressures.

Objectives: This study evaluates the impact of positive airway pressure (PAP) therapy on PH in patients admitted for ADHF with OSA. Read More

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https://academic.oup.com/sleep/advance-article/doi/10.1093/s
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http://dx.doi.org/10.1093/sleep/zsz100DOI Listing
April 2019
1 Read

Clinical Characteristics of Obstructive Sleep Apnea in Psychiatric Disease.

J Clin Med 2019 Apr 18;8(4). Epub 2019 Apr 18.

Division of Pulmonology, Department of Clinical Therapeutics, National and Kapodistrian University of Athens School of Medicine, Alexandra Hospital, 11528 Athens, Greece.

Patients with serious psychiatric diseases (major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia and psychotic disorder) often complain about sleepiness during the day, fatigue, low energy, concentration problems, and insomnia; unfortunately, many of these symptoms are also frequent in patients with Obstructive Sleep Apnea (OSA). However, existing data about the clinical appearance of OSA in Psychiatric Disease are generally missing. The aim of our study was a detailed and focused evaluation of OSA in Psychiatric Disease, in terms of symptoms, comorbidities, clinical characteristics, daytime respiratory function, and overnight polysomnography data. Read More

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https://www.mdpi.com/2077-0383/8/4/534
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http://dx.doi.org/10.3390/jcm8040534DOI Listing
April 2019
1 Read

Intracranial volume versus static and pulsatile intracranial pressure values in children with craniosynostosis.

J Neurosurg Pediatr 2019 Apr 19:1-9. Epub 2019 Apr 19.

1Department of Neurosurgery, Oslo University Hospital-Rikshospitalet, Oslo, Norway; and.

OBJECTIVEReduced intracranial volume (ICV) and raised intracranial pressure (ICP) are assumed to be principal pathophysiological mechanisms in childhood craniosynostosis. This study examined the association between ICV and ICP and whether ICV can be used to estimate the ICP.METHODSThe authors analyzed ICV and ICP measurements from children with craniosynostosis without concurrent hydrocephalus and from age-matched individuals without craniosynostosis who underwent diagnostic ICP measurement. Read More

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http://dx.doi.org/10.3171/2019.2.PEDS18767DOI Listing
April 2019
1 Read

What Are the Characteristics of the Upper Airway in Patients With Craniofacial Microsomia?

J Oral Maxillofac Surg 2019 Mar 26. Epub 2019 Mar 26.

Associate Professor, Dutch Craniofacial Center, Department of Oral and Maxillofacial Surgery, Erasmus University Hospital, Sophia Children's Hospital Rotterdam, Rotterdam, The Netherlands; Craniofacial Unit, Great Ormond Street Hospital, London, UK; Craniofacial Center, Department of Plastic and Oral Surgery, Boston Children's Hospital, Boston, MA.

Purpose: Obstructive sleep apnea (OSA) is a common problem in patients with craniofacial microsomia (CFM); however, the exact pathophysiology in patients with CFM remains unclear. The first aim of this study was to evaluate upper airway volume and morphology in patients with CFM. The second aim was to identify risk factors for the presence of OSA. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02782391193034
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http://dx.doi.org/10.1016/j.joms.2019.03.017DOI Listing
March 2019
1 Read

Plasm YKL-40 Levels Are Associated with Hypertension in Patients with Obstructive Sleep Apnea.

Biomed Res Int 2019 13;2019:5193597. Epub 2019 Mar 13.

Department of Otolaryngology, Beijing AnZhen Hospital, Capital Medical University, Beijing 100029, China.

Background: Obstructive sleep apnea (OSA) is a common disease. It can cause many serious complications. OSA may increase the risk of hypertension. Read More

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http://dx.doi.org/10.1155/2019/5193597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436335PMC

Sleep disturbances in HIV-infected patients associated with depression and high risk of obstructive sleep apnea.

SAGE Open Med 2019 8;7:2050312119842268. Epub 2019 Apr 8.

Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Objective: To evaluate sleep disturbances in a diverse, contemporary HIV-positive patient cohort and to identify demographic, clinical, and immune correlates.

Methods: A convenience sample of 176 patients from a racially and ethnically diverse HIV-positive patient cohort in an urban population. This was a cross-sectional, epidemiologic study. Read More

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http://dx.doi.org/10.1177/2050312119842268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454647PMC
April 2019
1 Read

Upper Airway Video Endoscopy: Assessment of the response to positive pressure ventilation and mechanical in-exsufflation.

Pulmonology 2019 Apr 15. Epub 2019 Apr 15.

Faculdade de Medicina da Universidade do Porto, Porto, Portugal.

Upper airways (UA) include the nasal cavities, pharynx, and larynx, and its main function is to warm and filter the inspired air. UA dysfunction is in the pathogenesis of various disorders, such as obstructive sleep apnea syndrome (OSAS) and vocal cord dysfunction. In addition, in some neurodegenerative diseases (e. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S25310437193004
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http://dx.doi.org/10.1016/j.pulmoe.2019.02.008DOI Listing
April 2019
1 Read

Sleep-related breathing disorders in young adults with Prader-Willi syndrome: a placebo-controlled, cross-over GH trial.

J Clin Endocrinol Metab 2019 Apr 18. Epub 2019 Apr 18.

Dutch Growth Research Foundation, Rotterdam, The Netherlands.

Context: Sleep-related breathing disorders (SRBD) are common in people with Prader-Willi syndrome (PWS). Young adults with PWS benefit from GH continuation after adult height by maintaining the improved body composition obtained during childhood. There are, however, no studies about the effects of GH on SRBD in young adults with PWS who were treated with GH during childhood. Read More

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http://dx.doi.org/10.1210/jc.2019-00391DOI Listing

Adenotonsillectomy in children with syndromic craniosynostosis: a systematic review and meta-analysis.

Eur Arch Otorhinolaryngol 2019 Apr 17. Epub 2019 Apr 17.

Department of Otorhinolaryngology Head and Neck Surgery, Police General Hospital, 492/1 Rama 1 Road, Patumwan, Bangkok, Thailand.

Objective: To conduct a systematic review and meta-analysis in children with syndromic craniosynostosis, to evaluate the effect of adenotonsillectomy for the treatment of obstructive sleep apnea (OSA).

Study Design: A systematic review and meta-analysis.

Search Methods: Data sources: a comprehensive search of PubMed, SCOPUS, Ovid Medline, and Web of science databases was performed through June 22nd, 2018. Read More

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http://dx.doi.org/10.1007/s00405-019-05427-3DOI Listing

Preoperative stratification for postoperative delirium: obstructive sleep apnea is a predictor, the STOP-BANG is not?

J Thorac Dis 2019 Mar;11(Suppl 3):S202-S206

Department of Anaesthesia and Critical Care Medicine, Policlinico Umberto 1 Hospital, Sapienza University of Rome, Rome, Italy.

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http://dx.doi.org/10.21037/jtd.2019.02.33DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424745PMC
March 2019
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Automated sleep stage classification based on tracheal body sound and actigraphy.

Ger Med Sci 2019 22;17:Doc02. Epub 2019 Feb 22.

Department of Internal Medicine II, University Hospital Ulm, Germany.

The current gold standard for assessment of most sleep disorders is the in-laboratory polysomnography (PSG). This approach produces high costs and inconveniences for the patients. An accessible and simple preliminary screening method to diagnose the most common sleep disorders and to decide whether a PSG is necessary or not is therefore desirable. Read More

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http://www.egms.de/en/journals/gms/2019-17/000268.shtml
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http://dx.doi.org/10.3205/000268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449867PMC
February 2019
3 Reads

Obstructive sleep apnoea in patients with fibrotic diffuse parenchymal lung disease-characterization and treatment compliance assessment.

Can J Respir Ther 2018 1;54(2):35-40. Epub 2018 Aug 1.

Pulmonology Department, Centro Hospitalar São João, Oporto, Portugal.

Introduction: Recent studies have reported a high prevalence of obstructive sleep apnoea (OSA) among patients with diffuse parenchymal lung disease (DPLD), mainly idiopathic pulmonary fibrosis (IPF). Effective OSA treatment appears to have a positive impact on morbidity and mortality in these patients. However, poor compliance to positive airway pressure (PAP) treatment in fibrotic DPLD patients has been reported. Read More

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http://dx.doi.org/10.29390/cjrt-2018-005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6422053PMC
August 2018
1 Read

The Interaction Between Craniofacial Computed Tomographic Dimensional Parameters and BMI in Obstructive Sleep Apnea.

J Maxillofac Oral Surg 2019 Jun 27;18(2):299-306. Epub 2018 Aug 27.

1Department of Otolaryngology Head & Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, 6 Weizman St., Tel-Aviv, 6423906 Israel.

Introduction: The impact of the dimensional parameters of the pharyngeal bony frame by its length, width and the position of the hyoid upon the severity of obstructive sleep apnea syndrome (OSAS) has not been investigated in depth. Interactions of those parameters with body mass index (BMI) and their overall reciprocal effect on OSAS severity have also not been established.

Materials And Methods: This retrospective cross-sectional study was conducted on 108 male OSAS patients followed in OSAS outpatient clinics between November 2014 and October 2015. Read More

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http://dx.doi.org/10.1007/s12663-018-1140-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441440PMC

[Association of sleep overlap syndrome with type 2 diabetes in a cross-sectional study].

Authors:
J Xie F Li

Beijing Da Xue Xue Bao Yi Xue Ban 2019 Apr;51(2):252-255

Department of Respiratory and Critical Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing 100023, China.

Objective: Growing evidence indicates that both chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) may be related to increased risk of developing metabolic disorder and cardiovascular diseases. However, the association of sleep overlap syndrome (combination of COPD and OSA) with type 2 diabetes is unclear. The aim of this study was to investigate the association between overlap syndrome and prevalence of type 2 diabetes. Read More

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April 2019
2 Reads

Prevalence of Rapid Eye Movement-related Obstructive Sleep Apnea in Adult Narcolepsy.

Intern Med 2019 Apr 17. Epub 2019 Apr 17.

Department of Sleep Medicine and Sleep Disorders Center, Aichi Medical University Hospital, Japan.

Objective The association between narcolepsy and rapid eye movement (REM)-related obstructive sleep apnea (OSA) has not been reported. This study aimed to examine the prevalence of REM-related OSA in narcolepsy patients. Methods From January 2013 to April 2018, 141 adult patients were diagnosed with narcolepsy using nocturnal polysomnography and the multiple sleep latency test. Read More

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https://www.jstage.jst.go.jp/article/internalmedicine/advpub
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http://dx.doi.org/10.2169/internalmedicine.2601-18DOI Listing
April 2019
7 Reads

Sleep disorders in polycystic ovary syndrome: influence of obesity and hyperandrogenism.

Rev Assoc Med Bras (1992) 2019 Mar 11;65(3):375-383. Epub 2019 Apr 11.

Department of Psychobiology, Federal University of Sao Paulo, Sao Paulo, SP, Brasil.

Objective: This study aims to evaluate the sleep of subjects with polycystic ovary syndrome (PCOS), with and without hyperandrogenism, in comparison with a healthy control group and examine the effects of hyperandrogenism and obesity on sleep parameters.

Methods: A total of 44 volunteers were recruited to participate in the study. Clinical, biochemical and polysomnographic parameters were used to diagnose PCOS and hyperandrogenism. Read More

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S
Publisher Site
http://dx.doi.org/10.1590/1806-9282.65.3.375DOI Listing
March 2019
2 Reads

Obstructive sleep apnea, nighttime arousals, and leukocyte telomere length: The Multi-Ethnic Study of Atherosclerosis (MESA).

Sleep 2019 Apr 17. Epub 2019 Apr 17.

Departments of Medicine, Brigham and Women's Hospital and Beth Israel Deaconess Medical Center, Harvard Medical School.

Study Objectives: Sleep disturbances and sleep apnea are associated with increased vulnerability to age-related disease, altering molecular pathways affecting biological aging. Telomere length captures one component of biological aging. We evaluated whether objectively assessed sleep and sleep apnea relate to leukocyte telomere length (LTL) in the Multi-Ethnic Study of Atherosclerosis (MESA). Read More

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https://academic.oup.com/sleep/advance-article/doi/10.1093/s
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http://dx.doi.org/10.1093/sleep/zsz089DOI Listing
April 2019
2 Reads

Metabolic Consequences of Obstructive Sleep Apnea Especially Pertaining to Diabetes Mellitus and Insulin Sensitivity.

Diabetes Metab J 2019 Apr;43(2):144-155

Epidemiologic Research and Information Center, Veterans Affairs Puget Sound Health Care System, Seattle, WA, USA.

Obstructive sleep apnea (OSA) and diabetes has been known to be closely related to each other and both diseases impact highly on the public health. There are many evidence of reports that OSA is associated with diabetes with a bidirectional correlation. A possible causal mechanism of OSA to diabetes is intermittent hypoxemia and diabetes to OSA is microvascular complication. Read More

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http://dx.doi.org/10.4093/dmj.2018.0256DOI Listing
April 2019
1 Read

Does drug-induced sleep endoscopy affect surgical outcome? A multicenter study of 326 obstructive sleep apnea patients.

Laryngoscope 2019 Apr 17. Epub 2019 Apr 17.

Otolaryngology Department, Western University, London, Ontario, Canada.

Objectives/hypothesis: Our objective was to determine whether drug-induced sleep apnea (DISE) affects the successfulness of the surgical outcome.

Study Design: Prospective, seven-country, nonrandomized trial.

Methods: There were 326 consecutive obstructive sleep apnea (OSA) patients who had nose, palate, and/or tongue surgery included in the study. Read More

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http://dx.doi.org/10.1002/lary.27987DOI Listing
April 2019
1 Read
2.032 Impact Factor

Barbed suspension pharyngoplasty for treatment of lateral pharyngeal wall and palatal collapse in patients affected by OSAHS.

Eur Arch Otorhinolaryngol 2019 Apr 16. Epub 2019 Apr 16.

IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Purpose: The aim of this study is to analyze the efficacy of a new modified pharyngoplasty technique with barbed sutures: barbed suspension pharyngoplasty (BSP).

Methods: We enrolled patients affected by obstructive sleep apnea-hypopnea syndrome (OSAHS), having the main site of obstruction at the palatal and lateral pharyngeal walls, who refused or failed to tolerate CPAP therapy and underwent non-resective pharyngoplasty with barbed sutures between January 2014 and October 2017. Two surgical techniques with barbed sutures were used: barbed reposition pharyngoplasty (BRP) and BSP; the main characteristics of the latter are a double passage of the needle, each side, through the soft palate. Read More

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http://dx.doi.org/10.1007/s00405-019-05426-4DOI Listing
April 2019
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Influence of short-term side effects on oral sleep appliance compliance among CPAP-intolerant patients: An objective monitoring of compliance.

J Oral Rehabil 2019 Apr 16. Epub 2019 Apr 16.

Department of Restorative Dentistry, Faculty of Dentistry, National University of Singapore, Singapore.

Objectives: To investigate the predictive value of side effects on usage times during the initial titration phase of oral appliance therapy for sleep apnea. The secondary objective was to assess the correlation between subjective and objective usage times.

Methods: 21 subjects diagnosed with sleep apnea and a history of non-compliance with CPAP therapy, were enrolled in the 4-week clinical study. Read More

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http://dx.doi.org/10.1111/joor.12802DOI Listing
April 2019
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Effects of an Adenotonsillectomy on the Cognitive and Behavioural Function of Children Who Snore: A naturalistic observational study.

Sultan Qaboos Univ Med J 2018 Nov 28;18(4):e455-e460. Epub 2019 Mar 28.

Department of Surgery, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman.

Objectives: This study aimed to evaluate cognitive and behavioural changes among 9-14-year-old Omani children with obstructive sleep apnoea (OSA) after an adenotonsillectomy (AT).

Methods: This naturalistic observational study was conducted at the Sultan Qaboos University Hospital, Muscat, Oman, between January 2012 and December 2014. Omani children with adenotonsillar hypertrophy (ATH) underwent overnight polysomnography and those with confirmed OSA were scheduled for an AT. Read More

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http://dx.doi.org/10.18295/squmj.2018.18.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443270PMC
November 2018
1 Read

The Incidence of Sleep Disordered Breathing One Week After Primary Palatoplasty: Evaluation With Overnight Pulse Oximetry.

J Craniofac Surg 2019 Apr 10. Epub 2019 Apr 10.

Department of Otolaryngology, National Center for Child Health and Development, Tokyo, Japan.

Background: Sleep disordered breathing (SDB) is defined as a series of disorders including snoring, obstructive sleep apnea, and hypopnea. Few studies investigated the incidence of SDB following primary palatoplasty with objective testing. The aims of this study were to elucidate the prevalence and degree of SDB approximately 1 week following primary palatoplasty with objective testing and to clarify the risk factors. Read More

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http://dx.doi.org/10.1097/SCS.0000000000005530DOI Listing
April 2019
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Outcomes and Safety Among Patients With Obstructive Sleep Apnea Undergoing Cancer Surgery Procedures in a Freestanding Ambulatory Surgical Facility.

Anesth Analg 2019 Apr 8. Epub 2019 Apr 8.

From the *Department of Anesthesiology and Critical Care, Josie Robertson Surgery Center †Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York.

Background: Patients with obstructive sleep apnea (OSA) may be at increased risk for serious perioperative complications. The suitability of ambulatory surgery for patients with OSA remains controversial, and several national guidelines call for more evidence that assesses clinically significant outcomes. In this study, we investigate the association between OSA status (STOP-BANG risk, or previously diagnosed) and short-term outcomes and safety for patients undergoing cancer surgery at a freestanding ambulatory surgery facility. Read More

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http://dx.doi.org/10.1213/ANE.0000000000004111DOI Listing
April 2019
1 Read

Uncommon cause of persistent hypoxia in a patient with obstructive sleep apnea.

J Family Med Prim Care 2019 Feb;8(2):763-765

Department of Medicine, Smt. Sucheta Kriplani Hospital and LHMC, New Delhi, India.

We report a case of hypothyroidism, obstructive sleep apnea (OSA) with persistent daytime hypoxemia. Cause of hypoxemia was two arteriovenous (AV) malformations in the lower lobe of the lung. We must be alert to other causes of hypoxemia in patients of OSA with persistent daytime hypoxemia. Read More

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http://www.jfmpc.com/text.asp?2019/8/2/763/252994
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http://dx.doi.org/10.4103/jfmpc.jfmpc_3_19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436244PMC
February 2019
2 Reads

Hydrogen and Oxygen Mixture to Improve Cardiac Dysfunction and Myocardial Pathological Changes Induced by Intermittent Hypoxia in Rats.

Oxid Med Cell Longev 2019 7;2019:7415212. Epub 2019 Mar 7.

Department of Physiology, Institute of Basic Medicine, Hebei University of Chinese Medicine, Shijiazhuang 050200, China.

Obstructive sleep apnea (OSA) can cause intermittent changes in blood oxygen saturation, resulting in the generation of many reactive oxygen species (ROS). To discover new antioxidants and clarify the endoplasmic reticulum (ER) stress involved in cardiac injury in OSA, we established a chronic intermittent hypoxia (CIH) rat model with a fraction of inspired O (FiO) ranging from 21% to 9%, 20 times/h for 8 h/day, and the rats were treated with H-O mixture (67% hydrogen and 33% oxygen) for 2 h/day for 35 days. Our results showed that H-O mixture remarkably improved cardiac dysfunction and myocardial fibrosis. Read More

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http://dx.doi.org/10.1155/2019/7415212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431505PMC
March 2019
1 Read

Editorial: Neuroimaging Findings in Sleep Disorders and Circadian Disruption.

Front Neurol 2019 21;10:249. Epub 2019 Mar 21.

Department of Psychiatry and Psychotherapy, Faculty of Medicine, Medical Center - University of Freiburg, Freiburg, Germany.

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https://www.frontiersin.org/article/10.3389/fneur.2019.00249
Publisher Site
http://dx.doi.org/10.3389/fneur.2019.00249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448031PMC
March 2019
2 Reads

Effects of Insomnia and Depression on CPAP Adherence in a Military Population.

Fed Pract 2019 Mar;36(3):134-139

is a Clinical Nurse Specialist and is Chair of Pulmonary and Sleep Medicine, both in the Department of Pulmonary, Critical Care, and Sleep Medicine at the Naval Medical Center San Diego in California. is a Senior Scientist, Leidos and is a Sleep Research Physiologist, both in the Warfighter Performance Department of the Naval Health Research Center in San Diego.

Initial self-reported depression and insomnia prior to the diagnosis and treatment of obstructive sleep apnea with continuous positive airway pressure therapy did not reliably predict short- and long-term adherence in a sample of active-duty military and veteran patients. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453608PMC
March 2019
4 Reads

Morphometric and functional connectivity changes in the brain of patients with obstructive sleep apnea: A meta-analysis.

Authors:
Andy W K Yeung

J Sleep Res 2019 Apr 14:e12857. Epub 2019 Apr 14.

Oral and Maxillofacial Radiology, Applied Oral Sciences, Faculty of Dentistry, University of Hong Kong, Hong Kong SAR, China.

Existing evidence for brain morphometric changes and functional connectivity alterations in patients with obstructive sleep apnea is mixed. The current study aimed to meta-analyse the neuroimaging data, and thus synthesize a brain map showing locations with morphometric and functional connectivity differences between patients with obstructive sleep apnea and controls. Published studies to 2018 were retrieved and included into the analysis if they reported such between-group differences using voxel-based morphometry or resting-state functional magnetic resonance imaging, and reported the results in the form of brain coordinates based on whole-brain analysis. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/jsr.12857
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http://dx.doi.org/10.1111/jsr.12857DOI Listing
April 2019
2 Reads

Overexpressed long noncoding RNA CPS1-IT alleviates pulmonary arterial hypertension in obstructive sleep apnea by reducing interleukin-1β expression via HIF1 transcriptional activity.

J Cell Physiol 2019 Apr 14. Epub 2019 Apr 14.

Department of Respiratory Medicine, Shanghai University of Medicine & Health Sciences Affiliated Zhoupu Hospital, Shanghai, China.

Pulmonary arterial hypertension (PAH) is characterized by pulmonary vascular remodeling of the precapillary pulmonary arteries, with excessive proliferation of vascular cells. This study was performed to examine the effects of long noncoding RNA CPS1 intronic transcript 1 (CPS1-IT) on PAH in rat models of obstructive sleep apnea (OSA) through regulating interleukin (IL)-1β expression. The OSA models were induced in rats, for determination of the CPS1-IT expression. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1002/jcp.28571
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http://dx.doi.org/10.1002/jcp.28571DOI Listing
April 2019
5 Reads

Prediction of new onset atrial fibrillation in patients with acute pulmonary embolism: The role of sPESI Score.

Turk Kardiyol Dern Ars 2019 Apr;47(3):191-197

Department of Cardiology, Türkiye Yüksek Ihtisas Training and Research Hospital, Ankara, Turkey.

Objective: Acute pulmonary embolism (APE) is a serious clinical situation and atrial fibrillation (AF) is the most common arrhytmia in clinical practice. The Pulmonary Embolism Severity Index (PESI) is an accepted risk stratification tool used to predict short term mortality in APE. The aim of this study was to evaluate the relationship between the PESI score and new-onset AF in patients with APE. Read More

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http://archivestsc.com/jvi.aspx?un=TKDA-78241
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http://dx.doi.org/10.5543/tkda.2018.78241DOI Listing
April 2019
3 Reads

[Altered regional brain activity of functional connectivity in patients with obstructive sleep apnea].

Zhonghua Yi Xue Za Zhi 2019 Apr;99(14):1095-1100

Department of Radiology, Children's Hospital, Nanjing Medical University, Nanjing 210008, China.

To investigate the changes of default mode network in subjects with obstructive sleep apnea (OSA) using functional connectivity (FC). Clinical data were collected from thirty-three subjects with OSA who went to the Zhongda Hospital, Southeast University, and twenty-nine normal controls were recruited from community from Jan 2016 to Jan 2018. The OSA group was divided into two subgroups according to apnea-hypopnea index (AHI) and the lowest oxygen saturation at night: 15 patients in the mild group and 18 in the moderate to severe group. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.14.012DOI Listing
April 2019
2 Reads

Head jerks during sleep in a patient with obstructive sleep apnea.

Sleep Med 2019 Feb 28;57:141-143. Epub 2019 Feb 28.

Department of Neurology, Seoul National University Hospital, Seoul, South Korea. Electronic address:

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http://dx.doi.org/10.1016/j.sleep.2019.02.013DOI Listing
February 2019
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Lingual (Not Palatine) Tonsillolith: Case Report.

J Oral Maxillofac Surg 2019 Mar 19. Epub 2019 Mar 19.

Director, Salivary Gland Center; Associate Dean, Clinical Professor, Division of Oral and Maxillofacial Surgery, Columbia University College of Dental Medicine, New York, NY. Electronic address:

The lingual tonsil (LT), located at the base of the tongue posterior to the circumvallate papillae, consists of aggregates of lymphoid tissue separated by a median glossoepiglottic ligament that splits the LT into right and left halves. Tonsillar tissue on either side of the ligament exhibits discrete round nodules that project upward. Each prominence is covered by nonkeratinized epithelium and has a central crypt formed by an invagination of the overlying epithelium. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02782391193027
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http://dx.doi.org/10.1016/j.joms.2019.03.006DOI Listing
March 2019
2 Reads
1.280 Impact Factor

Acne keloidalis nuchae and obstructive sleep apnea: a retrospective case series.

Clin Exp Dermatol 2019 Apr 13. Epub 2019 Apr 13.

Oregon Health and Science University, Department of Dermatology, Portland, Oregon, United States.

Acne keloidalis nuchae (AKN) is an inflammatory skin disease characterized by scarring of hair follicles along the posterior neck and scalp. Most commonly, AKN is attributed to follicular irritation from hair clippers, helmets, and other external sources. Alternative explanations for disease development posit AKN as a cutaneous symptom of metabolic syndrome - similar to acanthosis nigricans in the setting of diabetes mellitus (DM). Read More

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http://dx.doi.org/10.1111/ced.13985DOI Listing
April 2019
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[Anaesthesia in Adult Patients with Obesity].

Anasthesiol Intensivmed Notfallmed Schmerzther 2019 Apr 12;54(4):242-254. Epub 2019 Apr 12.

The prevalence of obesity has substantially increased worldwide during the last ten years. Hence, more anaesthetic procedures will be performed in obese patients in the future and more hospitals have to be prepared for the perioperative treatment of extremely obese patients including medical, technical and organisational issues. These include not only the management of the perioperative problems of adiposity, but also of its numerous concomitant diseases. Read More

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http://www.thieme-connect.de/DOI/DOI?10.1055/a-0636-2782
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http://dx.doi.org/10.1055/a-0636-2782DOI Listing
April 2019
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Analysis of oral microbiota in patients with obstructive sleep apnea-associated hypertension.

Hypertens Res 2019 Apr 11. Epub 2019 Apr 11.

Department of Respiratory and Critical Care Medicine, the Second Affiliated Hospital of Fujian Medical University, 362000, Quanzhou, China.

Obstructive sleep apnea-hypopnea syndrome (OSAHS) is an independent risk factor for hypertension (HTN). The oral microbiota plays a pathophysiological role in cardiovascular diseases; however, there are few reports directly investigating and identifying the organisms involved in OSAHS-related HTN. Therefore, this study aimed to identify those organisms. Read More

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http://www.nature.com/articles/s41440-019-0260-4
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http://dx.doi.org/10.1038/s41440-019-0260-4DOI Listing
April 2019
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Evaluation of quality of life, anxiety, and depression in the spouses of patients with obstructive sleep apnea syndrome.

Niger J Clin Pract 2019 Apr;22(4):516-520

Department of Chest Diseases, Trakya University School of Medicine, Edirne, Turkey.

Background: Impaired quality of life can be seen in the spouses of the obstructive sleep apnea syndrome (OSAS) patients. The main aim of the study is to assess the quality of life, anxiety, and depression in the spouses of the OSAS patients.

Materials And Methods: A total of 100 OSAS patients and their spouses were included in the study. Read More

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http://dx.doi.org/10.4103/njcp.njcp_500_18DOI Listing
April 2019
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Effect of arousal on sympathetic overactivity in patients with obstructive sleep apnea.

Sleep Med 2019 Feb 19. Epub 2019 Feb 19.

Department of Neurology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea. Electronic address:

Objective: Obstructive sleep apnea (OSA) is associated with sympathetic overactivity. Intermittent hypoxemia and repetitive arousals are the proposed mechanisms; however, the main contributing factor for sympathetic overactivity remains to be determined. We therefore investigated the independent effect of apnea or arousal on sympathetic activity in a large cohort of OSA patients using heart rate variability analysis. Read More

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http://dx.doi.org/10.1016/j.sleep.2019.01.044DOI Listing
February 2019
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Evaluation of the masticatory muscle function, physiological sleep variables, and salivary parameters after electromechanical therapeutic approaches in adult patients with Down syndrome: a randomized controlled clinical trial.

Trials 2019 Apr 11;20(1):215. Epub 2019 Apr 11.

Center of Biosciences Applied to Patients with Special Health Care Needs (CEBAPE), Institute of Science and Technology, São José dos Campos Campus, São Paulo State University-UNESP, R: Esperança 265, São Paulo, SP, Brazil.

Background: There are many comorbidities associated with Down syndrome (DS), including obstructive sleep apnea (OSA) and masticatory muscle alteration. Muscular hypotonia, in particular, of the masticatory and oropharyngeal muscles is one of the main characteristics of individuals with DS, resulting in impairments of speech, swallowing, and mastication in these individuals. In addition, total or partial obstruction of the airways during sleep can occur due to pharyngeal hypotonia, leading to snoring and to OSA. Read More

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http://dx.doi.org/10.1186/s13063-019-3300-0DOI Listing
April 2019
2 Reads
2.117 Impact Factor

Sleep disorders in NiemannPick disease type C, beyond cataplexy.

Sleep Med 2019 Feb 19;57:122-127. Epub 2019 Feb 19.

Division of Neurology, Department of Clinical Medicine, Universidade Federal do Ceará, Brazil; Neurology Service, Hospital Geral de Fortaleza, Fortaleza, Ceará, Brazil; Center of Health Sciences, Universidade Estadual do Ceará, Fortaleza, Ceará, Brazil. Electronic address:

Purpose: The aim of this study was to clinically characterize sleep disorders in a cohort of Niemann-Pick type C (NPC) patients, correlating these findings with disease features and polysomnographic (PSG) results.

Methods: We evaluated eight consecutive patients with molecular confirmation of NPC followed at the Hospital Geral de Fortaleza. Patients underwent a comprehensive neurological and sleep evaluation. Read More

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http://dx.doi.org/10.1016/j.sleep.2019.02.007DOI Listing
February 2019
2 Reads