34,365 results match your criteria Obstructive Sleep Apnea-Hypopnea Syndrome


Sleep architectural dysfunction and undiagnosed obstructive sleep apnea after chronic ischemic stroke.

Sleep Med 2021 Apr 15;83:45-53. Epub 2021 Apr 15.

The Florey Institute of Neuroscience and Mental Health, Melbourne, VIC, Australia; University of Melbourne, Melbourne, VIC, Australia.

Objective/background: Sleep-wake dysfunction is bidirectionally associated with the incidence and evolution of acute stroke. It remains unclear whether sleep disturbances are transient post-stroke or are potentially enduring sequelae in chronic stroke. Here, we characterize sleep architectural dysfunction, sleep-respiratory parameters, and hemispheric sleep in ischemic stroke patients in the chronic recovery phase compared to healthy controls. Read More

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Intermittent hypoxia changes the interaction of the kinin-VEGF system and impairs myocardial angiogenesis in the hypertrophic heart.

Physiol Rep 2021 May;9(9):e14863

Departamento de Psicobiologia, Universidade Federal de São Paulo, São Paulo, Brazil.

Intermittent hypoxia (IH) is a feature of obstructive sleep apnea (OSA), a condition highly associated with hypertension-related cardiovascular diseases. Repeated episodes of IH contribute to imbalance of angiogenic growth factors in the hypertrophic heart, which is key in the progression of cardiovascular complications. In particular, the interaction between vascular endothelial growth factor (VEGF) and the kallikrein-kinin system (KKS) is essential for promoting angiogenesis. Read More

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REM sleep latency as an independent risk for cardiovascular events in hemodialysis patients.

Physiol Rep 2021 May;9(9):e14837

Department of Nephrology, Shirasagi Hospital, Osaka, Japan.

Background: Clinical significance of objectively measured poor sleep quality (SQ) as a risk for cardiovascular disease (CVD) events is not well known in hemodialysis (HD) patients, independently of sleep-related breathing disorders (SRBDs) and sleep-related metabolic abnormality.

Methods: The present study investigated baseline levels of objective sleep architecture together with obstructive sleep apnea (OSA) and central sleep apnea (CSA) using polysomnography in 88 HD study participants (M/F, 56/32; age 68.4 ± 9. Read More

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Top 100 influential manuscripts in obstructive sleep apnea: a bibliometric analysis.

Sleep Breath 2021 May 15. Epub 2021 May 15.

Department of Physiology, School of Basic Medical Sciences, Xinjiang Medical University, No. 393 Xinyi Road, Urumqi, Xinjiang, China.

Objective: This study aimed to explore the characteristics of the top 100 influential manuscripts on obstructive sleep apnea (OSA).

Methods: All manuscripts in English were searched from the Thomson Reuters Web of Science database by using OSA-related terms and ranked based on citation frequency. The top 100 influential manuscripts were selected and further analyzed by author, subject, journal, year of publication, country of origin, and institution. Read More

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Effect of continuous positive airway pressure on albuminuria in patients with obstructive sleep apnea: a meta-analysis.

Sleep Breath 2021 May 15. Epub 2021 May 15.

Department of Obstetrics & Gynecology, Nanri Branch of the First Hospital of Putian City, Putian, Fujian, China.

Purpose: A relationship between albuminuria and obstructive sleep apnea (OSA) has been documented in previous studies. Nevertheless, the impact of continuous positive airway pressure (CPAP) treatment on albuminuria in subjects with OSA is debated. This meta-analysis was carried out to investigate whether or not CPAP treatment affected urinary albumin-to-creatinine ratio (UACR) in subjects with OSA. Read More

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Criteria for oral appliance and/or supine avoidance therapy selection based on outcome optimization and cost-effectiveness.

J Med Econ 2021 May 14. Epub 2021 May 14.

Sleep Data, LLC, San Diego, CA, USA.

Produce empirical support for further enhancements to a therapy selection protocol for obstructive sleep apnea (OSA) patients intolerant of positive airway pressure. A retrospective analysis was conducted in 101 men and 69 women patients. Two-night home sleep apnea studies were conducted at baseline and with a trial oral appliance. Read More

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Obstructive sleep apnea phenotypes and cardiovascular risk: Is there a role for heart rate variability in risk stratification?

Sleep 2021 May;44(5)

Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.

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Positive airway pressure (PAP) treatment reduces glycated hemoglobin (HbA1c) levels in obstructive sleep apnea patients with concomitant weight loss: Longitudinal data from the ESADA.

J Sleep Res 2021 May 14:e13331. Epub 2021 May 14.

Department of Chest Diseases, Ege University Faculty of Medicine, Izmir, Turkey.

Patients with obstructive sleep apnea (OSA) are at increased risk of developing metabolic disease such as diabetes. The effects of positive airway pressure on glycemic control are contradictory. We therefore evaluated the change in glycated hemoglobin (HbA1c) in a large cohort of OSA patients after long-term treatment with positive airway pressure. Read More

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A Pediatric Patient With Seizures and Vagus Nerve Stimulation With Worsening Snoring and Apneas.

Authors:
Sameh S Morkous

Cureus 2021 Apr 9;13(4):e14379. Epub 2021 Apr 9.

Pediatric Neurology, Lehigh Valley Health Network (LVHN) Lehigh Valley Reilly Children's Hospital, Allentown, USA.

An 11-year-old female presents to the sleep clinic for evaluation for possible sleep-disordered breathing (SDB). She has a history of frequently intractable seizures for which she was tried on multiple antiepileptic medications. She had vagus nerve stimulation (VNS) implantation two years ago to treat her focal seizures. Read More

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Sleep Bruxism: An Integrated Clinical View.

Sleep Med Clin 2021 Jun 18;16(2):373-380. Epub 2021 Apr 18.

Department of Integral Adult Care Dentistry, Temporomandibular Disorder and Orofacial Pain Program, Sleep & Pain Research Group, Faculty of Dentistry, Universidad de La Frontera, Avenida Francisco Salazar 01145, Temuco, Chile.

The vision of adult sleep bruxism (SB) has changed over time. Thus, among the most important concomitant factors of SB noted are the pathophysiological aspect, namely sleep arousal, obstructive sleep apnea, gastroesophageal pH/gastroesophageal reflux disease, and the use or abuse of certain substances. The aim of this article was to review the main clinically relevant pathophysiological SB-associated factors and a proposal for a diagnostic process. Read More

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Long-term periodontal changes associated with oral appliance treatment of obstructive sleep apnea.

J Clin Sleep Med 2021 May 14. Epub 2021 May 14.

Associate Professor, Faculty of Dentistry, University of British Columbia, Vancouver, British Columbia, Canada.

Study Objectives: To characterize the mandibular anterior teeth crown height as a marker of periodontal changes and bone loss as a side effect of an oral appliance (OA) worn for a minimum of 4.5 years.

Methods: This retrospective study conducted on patients with healthy baseline periodontiu m recruited participants from consecutive sleep apnea patients treated with an OA between 2004 to 2014. Read More

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Sleep apnea, coronary artery calcium density and cardiovascular events: results from the Multi-Ethnic Study of Atherosclerosis (MESA).

J Clin Sleep Med 2021 May 14. Epub 2021 May 14.

Icahn School of Medicine at Mount Sinai, New York, NY.

Study Objectives: Evaluate the association between obstructive sleep apnea (OSA), coronary artery calcium (CAC) density, and cardiovascular events in the Multi-Ethnic Study of Atherosclerosis (MESA).

Methods: We analyzed 1041 participants with non-zero CAC scores who had polysomnography and CAC density data from the fifth examination of MESA. OSA was defined as apnea-hypopnea index [AHI] ≥ 15 events/hour. Read More

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Nailfold Capillaroscopic changes of sleep apnea patients.

Microvasc Res 2021 May 10:104177. Epub 2021 May 10.

Samsun Education and Research Hospital, Department of Dermatology, TR-55000 İlkadim, Samsun (Turkey).

Background: Obstructive Sleep Apnea Syndrome (OSAS) have frequent association with comorbidities and this makes it an independent risk factor for cardiovascular disease. Not only endothelial dysfunction, but also arterial stiffening, increased inflammatory mediators, oxidative stress after hypoxemia that develops due to OSAS, cause vascular pathologies in all diameters of vessels. Nail bed capillaroscopy is a simple, noninvasive, useful method to examine microcirculation and evaluate nail bed capillary abnormalities in diseases that cause vascular damage. Read More

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Implementing a sleep technician supervised and personalized APAP interface fitting session prior to initiation of home APAP therapy improves adherence in patients with obstructive sleep apnea.

J Clin Sleep Med 2021 May 13. Epub 2021 May 13.

Department of Pulmonology and Critical Care, Ascension Genesys Hospital, Grand Blanc, MI.

Study Objectives: Home Automatic Positive Airway Pressure (APAP) therapy is becoming a mainstay treatment of obstructive sleep apnea (OSA). It is typically prescribed without any prior supervised titration. Initial experience of APAP treatment dictates subsequent use. Read More

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Association of obstructive sleep apnea risk with depression and anxiety symptoms in women with polycystic ovary syndrome.

J Clin Sleep Med 2021 May 13. Epub 2021 May 13.

Department of Obstetrics, Gynecology and Reproductive Sciences, Division of Reproductive Endocrinology and Infertility, University of California San Francisco, San Francisco, California.

Study Objective: To determine whether obstructive sleep apnea (OSA) risk is associated with depression and anxiety symptoms in women with polycystic ovary syndrome (PCOS).

Methods: This is a cross-sectional study of women with PCOS, by the Rotterdam criteria, seen at a single academic center between June 2017 and June 2020. Depression symptoms, anxiety symptoms and OSA risk were assessed with self-administered Patient Health Questionnaire-9 (PHQ-9), Generalized Anxiety Disorder-7 (GAD-7) and Berlin questionnaires, respectively. Read More

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[Corrigendum] TLR4 mediates inflammation and hepatic fibrosis induced by chronic intermittent hypoxia in rats.

Mol Med Rep 2021 Jul 13;24(1). Epub 2021 May 13.

Department of Infectious Diseases, The First Quanzhou Affiliated Hospital of Fujian Medical University, Quanzhou, Fujian 362000, P.r. china.

Following the publication of the above article, the authors have realized that the first grant number featured in the Funding section of the Declarations on p. 658 appeared incorrectly: The text here should have been written as 'grant nos. 2018J01199, 2018Y0032 and 2016J01441' instead of 'grant nos. Read More

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Cognitive Performance is Lower Among Individuals with Overlap Syndrome than with COPD or Obstructive Sleep Apnea Alone: Role of Carotid Artery Stiffness.

J Appl Physiol (1985) 2021 May 13. Epub 2021 May 13.

Department of Psychiatry, University of Iowa, Iowa City, IA, United Statesgrid.214572.7.

Background: Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea (OSA) are both independently associated with increased cardiovascular disease (CVD) risk and impaired cognitive function. It is unknown if individuals with both COPD and OSA (i.e. Read More

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Sleep-disordered breathing in the otorhinolaryngological practice.

J Biol Regul Homeost Agents 2021 Jan-Feb;35(1 Suppl. 2):27-32

Consultant allergist, Casa di Cura Villa Montallegro, Genoa, Italy.

Sleep-disordered breathing (SDB) is a common disorder in childhood. Snoring and obstructive sleep apnea represents a demanding challenge for both paediatricians and otolaryngologists. This real-life study investigated the association of demographic and clinical factors on snoring and sleep apnea in children consecutively visited. Read More

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Revisional Laparoscopic SADI-S vs. Duodenal Switch Following Failed Primary Sleeve Gastrectomy: a Single-Center Comparison of 101 Consecutive Cases.

Obes Surg 2021 May 12. Epub 2021 May 12.

Department of General and Digestive Surgery, Bariatric and Metabolic Surgery Unit, Bellvitge University Hospital, University of Barcelona, C/Feixa Llarga s/n. L'Hospitalet de Llobregat, 08907, Barcelona, Spain.

Background: Single-anastomosis duodeno-ileal bypass (SADI-S) is being proposed for obese patients with insufficient weight loss or weight regain after sleeve gastrectomy (SG), but limited information is available. The purpose of this study is to assess the safety and efficacy of SADI-S as a revisional surgery after SG, compared with standard duodenal switch (DS).

Methods: Unicentric cohort study including all patients submitted to SADI-S and DS after failed SG in a high-volume institution, between 2008 and 2020. Read More

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