37,232 results match your criteria Obstructive Sleep Apnea-Hypopnea Syndrome


The relationship of obesity and obstructive sleep apnea to the development of sarcoidosis: A large retrospective case-control US Veterans Administration analysis.

Chest 2022 May 18. Epub 2022 May 18.

Stratton VA Medical Center, Albany, NY.

Background: Previous studies have demonstrated an association between body mass index (BMI) and the development of sarcoidosis. We investigated this association and the association between obstructive sleep apnea (OSA) and the development of sarcoidosis in a US Veterans Administration database.

Research Questions: Is the presence of OSA or the BMI associated with the development of sarcoidosis over the subsequent 12 months?

Study Design And Methods: We identified patients with sarcoidosis and OSA through ICD-9 and ICD-10 codes. Read More

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Poor sleep Quality and Obstructive Sleep Apnea are Associated with Maternal Mood, and Anxiety Disorders in Pregnancy.

Matern Child Health J 2022 May 21. Epub 2022 May 21.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Background: Previous studies suggest sleep quality and obstructive sleep apnea (OSA) may be associated with psychiatric symptoms, including depression, anxiety, and posttraumatic stress disorder (PTSD). However, few studies have examined the relationship between sleep quality and OSA with maternal psychiatric symptoms during pregnancy, a state of vulnerability to these disorders.

Objective: The objective of our study is to examine the association between poor sleep quality and sleep apnea with antepartum depression, anxiety, and PTSD among pregnant women. Read More

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Electric field aspects in hypoglossal nerve stimulation for obstructive sleep apnea: A bilateral electrophysiological evaluation of unilateral electrode configuration changes.

J Sleep Res 2022 May 21:e13592. Epub 2022 May 21.

Department of Neurology, University of Lübeck, Lübeck, Germany.

Hypoglossal nerve stimulation is an established treatment option for obstructive sleep apnea in selected patients. A unilateral hypoglossal nerve stimulation system was approved a decade ago, yet the physiological effect of unilateral hypoglossal stimulation on bilateral tongue motion remains unclear. This study examined how electrode configuration, stimulation cuff position, or body mass index influenced the contralateral genioglossus electromyography (EMG) signal. Read More

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Ertugliflozin and incident obstructive sleep apnea: an analysis from the VERTIS CV trial.

Sleep Breath 2022 May 20. Epub 2022 May 20.

Section of Pulmonary, Critical Care and Sleep Medicine, Yale School of Medicine, New Haven, CT, USA.

Purpose: The sodium-glucose transporter 2 inhibitor (SGLT2i) empagliflozin may reduce the incidence of obstructive sleep apnea (OSA) in patients with type 2 diabetes (T2D) and cardiovascular (CV) disease. This analysis of VERTIS CV, the CV outcome trial for the SGLT2i ertugliflozin conducted in a similar group of patients, explored the effects of ertugliflozin on reported incident OSA.

Methods: In VERTIS CV, patients ≥ 40 years with T2D and atherosclerotic CV disease (ASCVD) were randomized to ertugliflozin 5 or 15 mg or placebo. Read More

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Validation of the traditional Chinese version of the Sinus and Nasal Quality of Life Survey (SN-5) for children.

Pediatr Neonatol 2022 May 2. Epub 2022 May 2.

Department of Chinese Medicine, China Medical University Hospital, Taichung, 404327, Taiwan; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, 404328, Taiwan; Chinese Medicine Research Center, China Medical University, Taichung, 404328, Taiwan; Research Center for Traditional Chinese Medicine, China Medical University Hospital, Taichung, 404327, Taiwan; Department of Laboratory Science and Biotechnology, Asia University, 413305, Taiwan. Electronic address:

Background: Persistent sinonasal symptoms are common in children with chronic rhinosinusitis. The Sinus and Nasal Quality of Life (QoL) Survey (SN-5) was the first validated questionnaire measuring sinonasal-related QoL in populations aged 2-12 years. No norm has been established for Chinese-speaking countries. Read More

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Bimaxillary Orthognathic Surgery Does Not Induce Obstructive Sleep Apnea in Skeletal Class III Patients, Regarding ApneaLink Device Results.

J Oral Maxillofac Surg 2022 Apr 25. Epub 2022 Apr 25.

Associate Professor, Oral and Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address:

Purpose: Since the relationship between mandibular setback surgery and obstructive sleep apnea (OSA) occurrence still remains controversial, the aim of this study was to assess the impact of bimaxillary orthognathic surgery on the probability of OSA development, using the ApneaLink device.

Methods: The authors implemented a double-blinded prospective cohort study. All healthy patients with skeletal class III deformity were included in this study. Read More

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Increasing obstructive sleep apnea risk is associated with hearing impairment in middle-aged Chinese men-A cross-sectional study.

PLoS One 2022 20;17(5):e0268412. Epub 2022 May 20.

Physical Examination Department, Beijing Tongren Hospital, Capital Medical University, Beijing, China.

Objective: Midlife males with obstructive sleep apnea (OSA) bear a high risk for cardiovascular diseases. However, the association of OSA and hearing impairment is controversial. Our objective was to observe the incidence of hearing loss in middle-aged males with different risks for OSA. Read More

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The invisible costs of obstructive sleep apnea (OSA): Systematic review and cost-of-illness analysis.

PLoS One 2022 20;17(5):e0268677. Epub 2022 May 20.

Faculty of Psychology, Vita-Salute San Raffaele University, Milan, Italy.

Background: Obstructive sleep apnea (OSA) is a risk factor for several diseases and is correlated with other non-medical consequences that increase the disease's clinical and economic burden. However, OSA's impact is highly underestimated, also due to substantial diagnosis gaps.

Objective: This study aims at assessing the economic burden of OSA in the adult population in Italy by performing a cost-of-illness analysis with a societal perspective. Read More

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Telehealth Technology Application in Enhancing Continuous Positive Airway Pressure Adherence in Obstructive Sleep Apnea Patients: A Review of Current Evidence.

Front Med (Lausanne) 2022 3;9:877765. Epub 2022 May 3.

Department of Respiratory and Critical Care Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Obstructive sleep apnea (OSA) is a common type of sleep-disordered breathing associated with multiple comorbidities. Continuous positive airway pressure (CPAP) is the first choice for moderate-severe OSA but poor compliance brings a great challenge to its effectiveness. Telehealth interventions ease the follow-up process and allow healthcare facilities to provide consistent care. Read More

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Pneumoparotid related to obstructive sleep apnea syndrome treated by oral appliance with anterior opening to reduce intraoral pressure.

Authors:
Kazuya Yoshida

Clin Case Rep 2022 May 12;10(5):e05816. Epub 2022 May 12.

Department of Oral and Maxillofacial Surgery National Hospital Organization Kyoto Medical Center Kyoto Japan.

Pneumoparotid is associated with retrograde air insufflation in Stensen's duct and the parotid gland. A 57-year-old man experienced swelling and pain in the right parotid region after sleeping during a flight. Pneumoparotid and obstructive sleep apnea syndrome were diagnosed. Read More

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Sex Differences in Excessive Daytime Sleepiness Among Patients With Obstructive Sleep Apnea.

J Clin Neurol 2022 May;18(3):351-357

Department of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Background And Purpose: To identify sex differences in daytime sleepiness associated with apnea severity and periodic limb movements during sleep (PLMS) in subjects with obstructive sleep apnea (OSA).

Methods: This study used the Epworth Sleepiness Scale (ESS), Beck Depression Inventory (BDI), and Sleep Hygiene Index (SHI) in logistic regression analyses with interaction terms. Severe OSA, excessive daytime sleepiness (EDS), and PLMS were defined as an apnea-hypopnea index of ≥30, an ESS score of ≥11, and a periodic limb movements index of >15, respectively. Read More

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Effects of Vagus Nerve Stimulation on Sleep-Disordered Breathing, Daytime Sleepiness, and Sleep Quality in Patients With Drug-Resistant Epilepsy.

J Clin Neurol 2022 May;18(3):315-322

Department of Neurology, Neuroscience Center, Samsung Medical Center, Samsung Biomedical Research Institute, Samsung Advanced Institute for Health Sciences & Technology (SAIHST), School of Medicine, SungKyunkwan University, Seoul, Korea.

Background And Purpose: This study aimed to determine the long-term effects of vagus nerve stimulation (VNS) on sleep-disordered breathing (SDB), daytime sleepiness, and sleep quality in patients with drug-resistant epilepsy (DRE). It also investigated the relationships among these main effects, clinical characteristics, and VNS parameters.

Methods: Twenty-four patients were recruited. Read More

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Body Mass Index Is Not an Independent Factor Associated With Recovery Room Length of Stay for Patients Undergoing Outpatient Surgery.

J Patient Saf 2022 May 18. Epub 2022 May 18.

Department of Anesthesiology, Division of Perioperative Informatics.

Objectives: Prolonged recovery time in the postanesthesia care unit (PACU) increases cost and administrative burden of outpatient surgical staff. The primary aim of this study was to determine whether body mass index (BMI) is associated with prolonged recovery in the PACU after outpatient surgery in a freestanding ambulatory surgery center.

Methods: We retrospectively studied 3 years of surgeries performed at a freestanding ambulatory surgery center. Read More

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The Pathogenesis of Central and Complex Sleep Apnea.

Curr Neurol Neurosci Rep 2022 May 19. Epub 2022 May 19.

Division of Critical Care, Sleep Medicine and Physiology, Department of Medicine, University of California San Diego, San Diego, CA, USA.

Purpose: The purpose of this article is to review the recent literature on central apnea. Sleep disordered breathing (SDB) is characterized by apneas (cessation in breathing), and hypopneas (reductions in breathing), that occur during sleep. Central sleep apnea (CSA) is sleep disordered breathing in which there is an absence or diminution of respiratory effort during breathing disturbances while asleep. Read More

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Diagnostic value of smartphone in obstructive sleep apnea syndrome: A systematic review and meta-analysis.

PLoS One 2022 19;17(5):e0268585. Epub 2022 May 19.

Department of Otolaryngology-Head and Neck Surgery, Bucheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Objectives: To assess the diagnostic utility of smartphone-based measurement in detecting moderate to severe obstructive sleep apnea syndrome (OSAS).

Methods: Six databases were thoroughly reviewed. Random-effect models were used to estimate the summary sensitivity, specificity, negative predictive value, positive predictive value, diagnostic odds ratio, summary receiver operating characteristic curve and measured the areas under the curve. Read More

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Sleep Apnea and Risk of Influenza-Associated Severe Acute Respiratory Infection: Real-World Evidence.

Nat Sci Sleep 2022 10;14:901-909. Epub 2022 May 10.

Faculty of Medicine, College of Medicine, Chang Gung University, Taoyuan, 333, Taiwan.

Purpose: We executed the presented retrospective cohort study with the purpose of probing the risk of severe acute respiratory infection (SARI) following influenza in patients with sleep apnea.

Materials And Methods: We executed this real-world study by gathering Taiwan National Health Insurance Research Database (NHIRD) data. From a database containing 1 million individuals sampled at random from the NHIRD, we identified all patients aged 20 years or older with a sleep apnea diagnosis between 1997 and 2013 as the study group. Read More

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Fluid-structure interaction modelling of the upper airway with and without obstructive sleep apnea: a review.

Med Biol Eng Comput 2022 May 18. Epub 2022 May 18.

Biomedical Engineering, University of Manitoba, Winnipeg, Canada.

Obstructive sleep apnea (OSA) is a common respiratory disorder associated with the collapse of the upper airway during sleep. OSA may cause oxygen desaturation, arousals from sleep, and daytime sleepiness, in turn affecting quality of life. There is low success rate in existing OSA surgical treatments mainly due to heterogeneity of the OSA population and poor understanding of the mechanism of the upper airway collapse in each individual. Read More

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Obesity effects on sleep quality with anthropometric and metabolic changes.

Rev Assoc Med Bras (1992) 2022 May;68(5):574-578

Sisli Hamidiye Etfal Training and Research Hospital, Otolaryngology Department - Istanbul, Turkey.

Objective: Obesity is one of the etiological factors of sleep disorders (e.g., obstructive sleep apnea and restless leg syndrome). Read More

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Obstructive Sleep Apnea: characterization of the obstructive site and type of collapse.

Codas 2022 16;34(5):e20210208. Epub 2022 May 16.

Programa de Pós-graduação em Fonoaudiologia, Pontifícia Universidade Católica de São Paulo - PUCSP - São Paulo (SP), Brasil.

Obstructive Sleep Apnea is characterized by recurrent episodes of partial or complete collapse of the pharynx, followed by decreased oxyhemoglobin saturation and frequent arousals. It is regarded as a public health issue with important night and day symptoms that impact life quality. Its effects are associated with the areas of competence of Speech and Language Pathologists. Read More

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Experiences with Continuous Positive Airway Pressure Among African American Patients and their Bed Partners.

Behav Sleep Med 2022 May 18:1-12. Epub 2022 May 18.

Population Health Research Institute, The MetroHealth Campus of Case Western Reserve University, Cleveland, Ohio, USA.

Rationale: Despite having a higher prevalence and severity of obstructive sleep apnea (OSA), African Americans have lower adherence to continuous positive airway pressure (CPAP) compared to other groups. Information regarding challenges faced by African Americans prescribed CPAP are lacking.

Objectives: To determine the barriers and facilitators to optimal management of OSA with CPAP among African Americans and to understand the role bed partners may play. Read More

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Relationship of bruxism with oral health-related quality of life and facial muscle pain in dentate individuals.

J Clin Exp Dent 2022 May 1;14(5):e385-e389. Epub 2022 May 1.

DDS, MS, PhD. Department of Diagnosis and Surgery, Araçatuba Dental School, São Paulo State University (UNESP), São Paulo, Brasil.

Background: To determine whether there is a correlation of bruxism (sleep, daytime, or both) with oral health-related quality of life and facial pain of muscular origin in dentate individuals.

Material And Methods: Seventy-four dentate patients (complete dentition) were included in this study. These individuals had pain in the facial muscles due to temporomandibular disorder (TMD). Read More

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Gut microbiota dysbiosis in 4- to 6-year-old children with obstructive sleep apnea-hypopnea syndrome.

Pediatr Pulmonol 2022 May 17. Epub 2022 May 17.

Ningbo Women and Children's Hospital, Ningbo, Zhejiang, China.

Objective: Several experiments on animals have reported the relationship between obstructive sleep apnea-hypopnea syndrome (OSAHS) and gut microbiota. We investigated the gut microbiota composition of children aged 4-6 years with OSAHS to complement the pathogenesis and clinical screening methods of OSAHS.

Methods: We collected feces from 43 children with OSAHS and 45 controls aged 4-6 years. Read More

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Validation of the French Cues to CPAP Use Questionnaire in patients with OSAS: A step forward for evaluating cues to CPAP use in order to predict treatment adherence.

J Psychosom Res 2022 May 13;158:110943. Epub 2022 May 13.

University Sleep Clinic, University Hospital of Bordeaux, Place Amélie Raba-Leon, 33 076 Bordeaux, France; USR CNRS 3413 SANPSY, University Hospital Pellegrin, University of Bordeaux, France. Electronic address:

Purpose: The cues to starting CPAP are important in patients with Obstructive Sleep Apnea Syndrome (OSAS) to predict CPAP use and behavioral change. The Cues to CPAP Use Questionnaire (CCUQ) is a short practical self-reported scale to evaluate such cues to action. This study sought to examine the psychometric reliability and validity of the French version. Read More

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Research trends in hypertension associated with obstructive sleep apnea: a bibliometric analysis.

Sleep Breath 2022 May 17. Epub 2022 May 17.

School of Nursing, Jilin University, 965 Xinjiang Street, Chaoyang District, Changchun, 130021, Jilin Province, China.

Objectives: The purpose of this study was to systematically analyze the studies of hypertension associated with obstructive sleep apnea to assess the current status and hot spots in this field.

Methods: We searched the Web of Science Core Collection for publications related to hypertension associated with obstructive sleep apnea published before July 3, 2021. Bibliometric analyses and science mappings were carried out using the CiteSpace 5. Read More

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Cardiovascular Benefit of CPAP in Adults with Coronary Artery Disease and OSA without Excessive Sleepiness.

Am J Respir Crit Care Med 2022 May 17. Epub 2022 May 17.

Brigham and Women's Hospital, 1861, Boston, Massachusetts, United States.

Rational: Randomized controlled trials of continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea (OSA) have not demonstrated protection against adverse cardiovascular outcomes. Recently, observational studies revealed that OSA-related cardiovascular risk is concentrated in patients with an elevated pulse rate response to respiratory events (ΔHR). Here, in this post-hoc analysis of a prospective clinical trial, we test the hypothesis that a greater pre-treatment ΔHR is associated with greater CPAP-related protection against adverse cardiovascular outcomes. Read More

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Impact Of Metabolic Risk Factors On Covid-19 Clinical Outcomes: An Extensive Review.

Curr Cardiol Rev 2022 May 9. Epub 2022 May 9.

Universidade Estácio de Sá Campus Presidente Vargas, Rio de Janeiro.

Background: Cardiovascular (CV) risk factors, particularly cardiometabolic, seem to be associated with heightened severity and increased morbimortality in patients infected by the novel Coronavirus disease-2019 (COVID-19).

Methods: A thorough scoping review was performed to elucidate and aggregate the latest evidence concerning the impact of an adverse cardiometabolic profile towards severity, morbimortality, and prognosis of COVID-19 infection.

Results: The pathophysiology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is complex, being characterized by viral-induced immune dysregulation and hypercytokinaemia, particularly in patients with critical disease, evolving with profound endothelial dysfunction, systemic inflammation, and prothrombotic state. Read More

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Is it necessary to perform a follow-up study after adenotonsillectomy in all children with moderate-severe obstructive sleep apnoea?

Acta Otorrinolaringol Esp (Engl Ed) 2022 May-Jun;73(3):191-195

Unidad Multidisciplinar de Sueño, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.

Hypertrophy of adenotonsillar tissue is the most common cause of OSAS in otherwise healthy children, and therefore adenotonsillectomy is the first line treatment. Scientific societies recommend nocturnal follow-up PSG to assess for residual OSAS in children with preoperative evidence for moderate to severe OSAS, obesity, craniofacial anomalies that obstruct the upper airway and neurological disorders, based on the increasing trend of publications reporting residual OSAS after adenotonsillectomy. Follow-up PSG values in children with a pre-operative diagnosis of severe OSAS were analysed retrospectively, and compared to the parents' impression after ENT surgery. Read More

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Polysomnographic validation of an under-mattress monitoring device in estimating sleep architecture and obstructive sleep apnea in adults.

Sleep Med 2022 Apr 22;96:20-27. Epub 2022 Apr 22.

Division of Sleep Medicine, Stanford University, Stanford, CA, USA. Electronic address:

Objective: The objective of this study is to evaluate the validity of an under-mattress monitoring device (Fullpower Technologies) in estimating sleep continuity and architecture, as well as estimating obstructive sleep apnea in an adult population.

Methods: Adult volunteers (n=102, 55% male and 45% female, aged 40.6 ± 13. Read More

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