Sleep 2022 Jun 11. Epub 2022 Jun 11.
Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, USA.
Study Objectives: Obstructive sleep apnea (OSA) is characterized by multiple "endotypic traits", including pharyngeal collapsibility, muscle compensation, loop gain, and arousal threshold. Here we examined 1) within-night repeatability, 2) long-term consistency, and 3) influences of body position and sleep state, of endotypic traits estimated from in-home polysomnography in mild-to-severe OSA (apnea-hypopnea index, AHI>5 events/hr).
Methods: Within-night repeatability was assessed using Multi-Ethnic Study of Atherosclerosis (MESA): Traits derived separately from "odd" and "even" 30-min periods were correlated and regression (error vs. Read More