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Sleep Med 2022 Jun 9;97:64-72. Epub 2022 Jun 9.

2nd Department of Respiratory Medicine, Institute of Tuberculosis and Lung Diseases, Warsaw, Poland.

Objective: In 2010, a questionnaire-based study on obstructive sleep apnea (OSA) management in Europe identified differences regarding reimbursement, sleep specialist qualification, and titration procedures. Now, 10 years later, a follow-up study was conducted as part of the ESADA (European Sleep Apnea Database) network to explore the development of OSA management over time.

Methods: The 2010 questionnaire including questions on sleep diagnostic, reimbursement, treatment, and certification was updated with questions on telemedicine and distributed to European Sleep Centers to reflect European OSA management practice. Read More

Sleep 2022 Jun 11. Epub 2022 Jun 11.

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital and Harvard Medical School, Boston, USA.

Study Objectives: Obstructive sleep apnea (OSA) is characterized by multiple "endotypic traits", including pharyngeal collapsibility, muscle compensation, loop gain, and arousal threshold. Here we examined 1) within-night repeatability, 2) long-term consistency, and 3) influences of body position and sleep state, of endotypic traits estimated from in-home polysomnography in mild-to-severe OSA (apnea-hypopnea index, AHI>5 events/hr).

Methods: Within-night repeatability was assessed using Multi-Ethnic Study of Atherosclerosis (MESA): Traits derived separately from "odd" and "even" 30-min periods were correlated and regression (error vs. Read More

J Clin Sleep Med 2022 Jun 11. Epub 2022 Jun 11.

Department of Otorhinolaryngology, Head and Neck Surgery, Cantonal Hospital Baselland, Liestal, Switzerland.

Study Objectives: To determine whether home sleep testing with peripheral arterial tonometry (HST-PAT) can be used in upper airway stimulation (UAS) to evaluate therapy success.

Methods: Data analysis from 50 consecutive UAS patients was performed. Baseline values were measured by polysomnography (PSG) and HST-PAT. Read More

Stud Health Technol Inform 2022 Jun;290:522-525

Sleep Medicine Unit, IRCCS ICS Maugeri, Pavia, Italy.

Obstructive sleep apnea (OSA) is a common sleep disorder and polysomnography (PSG) is the gold standard for its diagnosis and treatment monitoring. There are nowadays several activity trackers measuring sleep quality through the detection of sleep stages. To allow an easier monitoring of the treatment efficacy at home, this work explores the possibility of using one of those commercial smart-bands. Read More

J Clin Sleep Med 2022 06;18(6):1523-1530

University of Texas at San Antonio, San Antonio, Texas.

Study Objectives: Obstructive sleep apnea (OSA) is increasingly common among military personnel, but diagnostic capabilities are challenged by limited capability for polysomnography (PSG). We sought to evaluate the diagnostic properties of peripheral arterial tonometry (PAT)-based home sleep apnea testing (HSAT) to accurately identify and classify OSA among active-duty military personnel.

Methods: This study was a retrospective review of all patients suspected of having OSA who completed an initial PAT-based HSAT followed by confirmatory PSG within 120 days. Read More

Diagnostics (Basel) 2022 May 11;12(5). Epub 2022 May 11.

Institute of Metrology and Biomedical Engineering, Faculty of Mechatronics, Warsaw University of Technology, 02-525 Warsaw, Poland.

It is well documented that body position significantly affects breathing indices during sleep in patients with obstructive sleep apnea. They usually worsen while changing from a non-supine to a supine position. Therefore, body position should be an accurately measured and credible parameter in all types of sleep studies. Read More

J Oral Maxillofac Surg 2022 Apr 25. Epub 2022 Apr 25.

Associate Professor, Oral and Maxillofacial Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran. Electronic address:

Purpose: Since the relationship between mandibular setback surgery and obstructive sleep apnea (OSA) occurrence still remains controversial, the aim of this study was to assess the impact of bimaxillary orthognathic surgery on the probability of OSA development, using a home sleep test device.

Methods: The authors implemented a double-blinded prospective cohort study. All healthy patients with skeletal class III deformity were included in this study. Read More

Sleep Med 2022 Jul 23;95:105-111. Epub 2022 Apr 23.

Johns Hopkins University, School of Medicine, USA; University of Miami, Miller School of Medicine, USA.

Objectives: Continuous glucose monitoring (CGM) provides temporal data on glycemic variability, a predictor of outcomes related to type 2 diabetes mellitus. The current study sought to determine whether CGM-derived metrics in patients with type 2 diabetes are different in moderate-to-severe versus mild obstructive sleep apnea (OSA).

Methods: In adults with type 2 diabetes, home testing was used of assess the presence of OSA. Read More

Sleep Med 2022 Jul 29;95:76-83. Epub 2022 Apr 29.

HP2 Laboratory, Inserm U1300, Grenoble Alpes University, Grenoble, France; EFCR Laboratory, Thorax and Vessels Division, Grenoble Alpes University Hospital, Grenoble, France. Electronic address:

Background: Obstructive sleep apnea (OSA) remains massively underdiagnosed, due to limited access to polysomnography (PSG), the highly complex gold standard for diagnosis. Performance scores in predicting OSA are evaluated for machine learning (ML) analysis applied to 3D maxillofacial shapes.

Methods: The 3D maxillofacial shapes were scanned on 280 Caucasian men with suspected OSA. Read More

Int J Environ Res Public Health 2022 05 1;19(9). Epub 2022 May 1.

Department of Oral and Maxillo Facial Sciences, "Sapienza" University of Rome, 00161 Rome, Italy.

Introduction: OSAS is an emerging public health problem. Early diagnosis in adults with comorbidities is the gold standard to avoid complications caused by a late diagnosis. The aim of the study, part of the [email protected] project, was to identify within a population with dysmetabolic comorbidities the association of occlusal clinical signs, defined by orthodontic parameters, and of the anthropometric phenotype, with the severity of OSAS. Read More

Sleep 2022 05 2;45(5). Epub 2022 Feb 2.

Department of Engineering, Natural Interaction Lab, Thom Building, University of Oxford, Oxford, UK.

Study Objectives: This paper reports on the multicentric validation of a novel FDA-cleared home sleep apnea test based on peripheral arterial tonometry (PAT HSAT).

Methods: One hundred sixty-seven participants suspected of having obstructive sleep apnea (OSA) were included in a multicentric cohort. All patients underwent simultaneous polysomnography (PSG) and PAT HSAT, and all PSG data were independently double scored using both the recommended 1A rule for hypopnea, requiring a 3% desaturation or arousal (3% Rule), and the acceptable 1B rule for hypopnea, requiring a 4% desaturation (4% Rule). Read More

J Chin Med Assoc 2022 May 5. Epub 2022 May 5.

Department of Otorhinolaryngology-Head and Neck Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC.

Background: In-laboratory polysomnography (PSG) is the gold standard for diagnosing obstructive sleep apnea syndrome (OSAS). However, the long waiting list and sleeping at a hospital make patients hesitate to undergo the examination, thereby delaying diagnosis. During COVID-19 pandemic, sleep labs are almost closed, and the delay is worsening. Read More

Eur Oral Res 2022 Jan;56(1):1-9

Department of Orthodontics and Craniofacial Developmental Biology, Graduate School of Biomedical and Health Sciences, Hiroshima UniversityJapan.

Purpose: Several studies agree that an abnormal maxilla-mandible relationship correlates better as an Obstructive Sleep Apnea (OSA) predictor, rather than obesity. One of the orthodontic therapies recommended for this kind of craniofacial deformity is to advance the mandible forward with an orthodontic activator, therefore, the aim of this study is to determine if healthy children that use this appliance experience a widening of the upper airway as well as an improvement in their sleep-breathing patterns.

Materials And Methods: 39 healthy children, 20 for activator group (10 boys and 10 girls, 4 mean age 10. Read More

J Clin Sleep Med 2022 Apr 27. Epub 2022 Apr 27.

Study Objectives: As sleep latency is an important factor in the diagnosis of many disorders, it is important to know whether the patient's subjective evaluation of sleep latency corresponds with an objectively measured evaluation. Some studies indicate that patients usually overestimate their sleep latency. We sought to determine how comorbidities affect the patient's ability to assess their sleep latency. Read More

Clin Respir J 2022 May 24;16(5):352-360. Epub 2022 Apr 24.

The Second School of Clinical Medicine, Southern Medical University, Guangzhou, China.

The effect of long-term continuous positive airway pressure (CPAP) treatment on apnea-hypopnea index (AHI) after CPAP withdrawal remains unclear, especially in obstructive sleep apnea (OSA) patients screened from the population. To examine that, 1241 civil servants who participated in the annual physical examination were screened for OSA between September and December 2017. Screened OSA firstly underwent 1-week CPAP adherence assessment. Read More

Biol Res Nurs 2022 Jul 23;24(3):400-409. Epub 2022 Apr 23.

Department of Graduate Institute of Health Care, 63113Chang Gung University of Science and Technology, Toa-Yuan, Taiwan.

Being overweight or obese is regarded as crucial risk factors for obstructive sleep apnea (OSA). This study aimed to determine the influencing factors of overweight and obese employees with OSA in high-tech workplaces. A cross-sectional study design was employed. Read More

J Clin Sleep Med 2022 Apr 25. Epub 2022 Apr 25.

Monash Lung, Sleep, Allergy & Immunology, Monash Health, Melbourne, Australia.

Study Objectives: Supine predominant obstructive sleep apnea (OSA) is highly prevalent. The proportion of time spent in the supine position may be overrepresented during polysomnography, which would impact on the apnea-hypopnea index (AHI) and have important clinical implications. We aimed to investigate the difference in body position during laboratory or home polysomnography compared to habitual sleep and estimate its effect on OSA severity. Read More

BMC Pulm Med 2022 Apr 22;22(1):151. Epub 2022 Apr 22.

Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, 2 East Yinghua (Cherry Blossom) Road, Hepingli, Chaoyang District, Beijing, 100029, China.

Background: Adiposity is a well-established risk factor for obstructive sleep apnea (OSA), but whether a combination of preferable anthropometric measurements may improve the accuracy of detecting OSA is unknown. This study aimed to explore the accuracies of the waist-hip ratio (WHR) in conjunction with the body mass index (BMI) when identifying the severity of OSA.

Design: A total of 2012 participants in the China-Japan Friendship Hospital from January 2018 to December 2019 underwent anthropometric measurements and an overnight home sleep test (HST). Read More

J Sleep Res 2022 Apr 19:e13594. Epub 2022 Apr 19.

Respiratory Division and Sleep Laboratory, Montreal Chest Institute - McGill University Health Centre, Respiratory Epidemiology Clinical Research Unit and Meakins-Christie Laboratories, McGill University, Montreal, Quebec, Canada.

Cortical arousal-related hypopneas are not scored on type 3 home devices, which therefore limits their diagnostic accuracy for obstructive sleep apnea. The objective of this study was to evaluate whether scoring heart rate accelerations as surrogate markers of arousal improves type 3 portable monitor diagnostic agreement compared with polysomnography and improves therapeutic decision-making. We prospectively recruited patients evaluated for obstructive sleep apnea to undergo in-laboratory simultaneous full polysomnography + type 3 portable monitoring. Read More

Mayo Clin Proc Innov Qual Outcomes 2022 Apr 4;6(2):166-175. Epub 2022 Apr 4.

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.

Objective: To determine whether continuous positive airway pressure (CPAP) adherence reduces health care-related costs or use in patients with obstructive sleep apnea (OSA) and comorbid cardiovascular disease (CVD).

Patients: A total of 23 million patients with CVD were identified in the Medicare fee-for-service database. Of the 65,198 who completed a sleep study between January 2016 and September 2018, 55,125 were diagnosed as having OSA and 1758 were identified in the 5% Medicare durable medical equipment (DME) database. Read More

Obes Surg 2022 06 9;32(6):1814-1821. Epub 2022 Apr 9.

Department of Surgery, OLVG, Location West, Jan Tooropstraat 164, 1061 AE, Amsterdam, The Netherlands.

Background: Preoperative assessment of obstructive sleep apnea (OSA) in patients scheduled for bariatric surgery can be performed by in-laboratory polysomnography (PSG) or by portable polygraphy (PP) at home. We aimed to evaluate the association between PSG/PP, OSA diagnosis, and implementation of continuous positive airway pressure (CPAP) therapy.

Methods: All patients who underwent bariatric surgery from 2015 to 2017 were retrospectively reviewed. Read More

J Clin Sleep Med 2022 Apr 11. Epub 2022 Apr 11.

Sleep Unit, Department of Respiratory & Sleep Medicine, Royal Children's Hospital, Melbourne, Australia.

Study Objectives: The gold standard for diagnosis of pediatric obstructive sleep apnea is level 1 polysomnography (PSG). Some children are selected for unattended level 2 home sleep apnea testing (HSAT) with telehealth support, and we sought to review this home service.

Methods: A retrospective audit was conducted from 2013 to 2020. Read More

Ann Am Thorac Soc 2022 Apr 6. Epub 2022 Apr 6.

Brigham and Women's Hospital, Division of Sleep and Circadian Disorders, Boston, Massachusetts, United States.

Rationale: Recent prospective studies suggest diabetes as a risk factor for the development of obstructive sleep apnea (OSA). However, the extent to which diabetes-related traits, such as hyperglycemia and insulin resistance, are related to OSA risk remains uncertain.

Objectives: To examine risk of developing OSA according to baseline levels of fasting insulin and hemoglobin A1c (HbA1c). Read More

IEEE J Biomed Health Inform 2022 Apr 4;PP. Epub 2022 Apr 4.

Although obstructive sleep apnea and hypopnea syndrome (OSAHS) is a common sleep disease, it is sometimes difficult to be detected in time because of the inconvenience of polysomnography (PSG) examination. Since snoring is one of the earliest symptoms of OSAHS, it can be used for early OSAHS prediction. With the recent development of wearable and IoT sensors, we proposed a deep learning-based accurate snore detection model for long-term home monitoring of snoring during sleep. Read More

Front Neurosci 2022 15;16:726880. Epub 2022 Mar 15.

HP2 Laboratory, Inserm U1300, Grenoble Alpes University, Grenoble, France.

Background: The capacity to diagnose obstructive sleep apnoea (OSA) must be expanded to meet an estimated disease burden of nearly one billion people worldwide. Validated alternatives to the gold standard polysomnography (PSG) will improve access to testing and treatment. This study aimed to evaluate the diagnosis of OSA, using measurements of mandibular movement (MM) combined with automated machine learning analysis, compared to in-home PSG. Read More

BMC Pulm Med 2022 Apr 2;22(1):123. Epub 2022 Apr 2.

San Francisco VA Healthcare System, San Francisco, CA, USA.

Background: Obstructive sleep apnea (OSA) is a very common and serious health condition which is highly prevalent among U.S. military Veterans. Read More

Auris Nasus Larynx 2022 Mar 28. Epub 2022 Mar 28.

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

Objective: Polysomnography (PSG) is considered the gold standard for diagnosing obstructive sleep apnea syndrome (OSA) in children. However, many hospitals do not carry out PSG evaluations, and use out-of-center sleep test (OCST) devices for diagnosis instead. The aim of this study was to confirm the reliability of OCSTs for the diagnosis of pediatric OSA. Read More

Otolaryngol Head Neck Surg 2022 Mar 29:1945998221088752. Epub 2022 Mar 29.

Department of Otolaryngology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

Objective: To determine whether combined transoral robotic surgery and postoperative oropharyngeal rehabilitation are effective for reducing the severity of obstructive sleep apnea.

Study Design: A quasi-experimental study enrolled participants without blinding between May 2019 and April 2021.

Setting: Single-center study at National Cheng Kung University Hospital. Read More

Anaesthesia 2022 07 24;77(7):818-828. Epub 2022 Mar 24.

University Health Network, University of Toronto, Toronto, ON, Canada.

Identifying surgical patients with obstructive sleep apnoea may assist with anaesthetic management to minimise postoperative complications. Using trial sequential analysis, we evaluated the impact of obstructive sleep apnoea diagnosed by polysomnography or home sleep apnoea testing on postoperative outcomes in surgical patients. Multiple databases were systematically searched. Read More

Children (Basel) 2022 Feb 24;9(3). Epub 2022 Feb 24.

Department of Medicine, University of California San Francisco-Fresno, Fresno, CA 93701, USA.

Obstructive sleep apnea in children has been linked with behavioral and neurocognitive problems, impaired growth, cardiovascular morbidity, and metabolic consequences. Diagnosing children at a young age can potentially prevent significant morbidity associated with OSA. Despite the importance of taking a comprehensive sleep history and performing thorough physical examination to screen for signs and symptoms of OSA, these findings alone are inadequate for definitively diagnosing OSA. Read More