Search Our Scientific Publications & Authors

J Alzheimers Dis 2018 Dec 31. Epub 2018 Dec 31.

Advanced Brain Monitoring, Carlsbad, CA, USA.

Background: The characterization of sleep in those with neurodegenerative disease (NDD) is essential in understanding the potential neurobiological mechanisms that underlie the connection between sleep disruption and NDD manifestations and progression.

Objective: Explore the inter-relationships between NDD and age, sex, diagnosis of obstructive sleep apnea, snoring, and duration of sleep time with the head in the supine and non-supine positions.

Methods: A case-control design was used to evaluate differences in sleep position obtained from multi-night, in-home Sleep Profiler recordings in 45 patients with diagnosed NDD (24 with mild cognitive impairment, 15 with Alzheimer's disease, and 6 with Lewy Body, Parkinson's, or other dementias) and 120 age-sex matched controls with normal cognition (NC). Read More

Sleep Med 2018 Nov 30. Epub 2018 Nov 30.

Division of Pulmonary, Critical Care and Sleep Medicine, Yale New Haven Medical Center, Yale School of Medicine, 20 York Street New Haven, CT, 06510, USA. Electronic address:

Objective: Apnea/hypopnea index (AHI), especially without arousal criteria, does not adequately risk stratify patients with mild obstructive sleep apnea (OSA). We describe and test scoring reliability of an event, Flow Limitation/Obstruction With recovery breath (FLOW), representing obstructive airflow disruptions using only pressure transducer and snore signals available without electroencephalography.

Methods: The following process was used (i) Development of FLOW event definition, (ii) Training period and definition refinement, and (iii) Reliability testing on 10 100-epoch polysomnography (PSG) samples and two 100-sample tests. Read More

Ann Am Thorac Soc 2018 Dec 20. Epub 2018 Dec 20.

Brigham and Women's Hospital and Harvard Medical School, Division of Sleep and Circadian Disorders , Boston, Massachusetts, United States.

Rationale: Air pollution may influence sleep through airway inflammation or autonomic nervous system pathway alterations. Epidemiological studies may provide evidence of relationships between chronic air pollution exposure and sleep apnea.

Objective: To determine if ambient-derived pollution exposure was associated with obstructive sleep apnea and objective sleep disruption. Read More

Front Endocrinol (Lausanne) 2018 29;9:714. Epub 2018 Nov 29.

Second Internal Medicine Department, Vinohrady Teaching Hospital, Prague, Czechia.

Obstructive sleep apnea (OSA) is a common disorder in Type 2 diabetes (T2D) patients further increasing their already high cardiovascular risk. As T2D patients typically not report OSA symptoms, systematic screening for OSA in this population is warranted. We aimed to determine the readiness of T2D patients to undergo screening and to compare their adherence to continuous positive airway pressure (CPAP) therapy with "regular" sleep clinic patients who typically seek medical advice on their own initiative. Read More

Sleep Med 2018 Oct 24. Epub 2018 Oct 24.

Department of Medicine, Division of Neurology, University of Toronto, Canada; Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute, Toronto, Canada; L.C. Campbell Cognitive Neurology Research Unit, Heart and Stroke Foundation Canadian Partnership for Stroke Recovery, Sunnybrook Health Sciences Centre, Toronto, Canada; Sleep Laboratory, Sunnybrook Health Sciences Centre, Toronto, Canada. Electronic address:

Objective: Continuous positive airway pressure (CPAP) has been shown to improve functional, motor and cognitive outcomes in post-stroke obstructive sleep apnea (OSA). However, rates of CPAP adherence are often low and factors impacting CPAP adherence remain under-explored. Our objective was to determine predictors of CPAP adherence in patients who had a stroke or transient ischemic attack (TIA). Read More

J Clin Sleep Med 2018 Dec 15;14(12):2075-2077. Epub 2018 Dec 15.

University of Michigan Sleep Disorders Center, University of Michigan, Ann Arbor, Michigan.

Abstract: The diagnosis and effective treatment of obstructive sleep apnea (OSA) in adults is an urgent health priority. It is the position of the American Academy of Sleep Medicine (AASM) that only a medical provider can diagnose medical conditions such as OSA and primary snoring. Throughout this statement, the term "medical provider" refers to a licensed physician and any other health care professional who is licensed to practice medicine in accordance with state licensing laws and regulations. Read More

J Clin Sleep Med 2018 Dec 15;14(12):2083-2086. Epub 2018 Dec 15.

Fairview Health Services, Minneapolis, Minnesota; University of Minnesota, Minneapolis, Minnesota.

Abstract: Catathrenia is a rare sleep-related breathing disorder marked by nocturnal groaning during prolonged exhalation. Home sleep apnea tests are growing in popularity, but no prior case reports exist documenting catathrenia detected by a home sleep apnea test. We report two cases of catathrenia incidentally detected in patients with low to intermediate risk of obstructive sleep apnea, in which diagnostic polysomnography was recommended but denied by insurers. Read More

J Clin Sleep Med 2018 Dec 15;14(12):2065-2073. Epub 2018 Dec 15.

Department of Neurology, Boston Medical Center, Boston, Massachusetts.

Study Objectives: Sleep-disordered breathing (SDB) is highly prevalent in patients with acute stroke. SDB is often underdiagnosed and associated with neurological deterioration and stroke recurrence. Polysomnography or home sleep apnea testing (HSAT) is typically used as the diagnostic modality; however, it may not be feasible to use regularly in patients with acute stroke. Read More

J Sleep Res 2018 Nov 26:e12795. Epub 2018 Nov 26.

Département de Pneumologie, Centre Hospitalier Universitaire, Angers, France.

Polysomnography (PSG) is necessary for the accurate estimation of total sleep time (TST) and the calculation of the apnea-hypopnea index (AHI). In type III home sleep apnea testing (HSAT), TST is overestimated because of the lack of electrophysiological sleep recordings. The aim of this study was to evaluate the accuracy and reliability of a novel automated sleep/wake scoring algorithm combining a single electroencephalogram (EEG) channel with actimetry and HSAT signals. Read More

Pulmonology 2018 Nov 23. Epub 2018 Nov 23.

Respiratory Failure Unit, G. Papanikolaou Hospital, Aristotle University of Thessaloniki, Greece.

Objectives: Obstructive sleep apnea syndrome (OSA) is a cause of high morbidity and mortality so diagnosis and treatment is essential. Questionnaires and oximetry have been used for OSA screening.

Aim: To evaluate the clinical utility of different sleep questionnaires (Stop Bang (S-B), Berlin (BQ), Epworth Sleepiness Scale (ESS)) in deciding on treatment with Continuous Positive Airway Pressure (CPAP) and to examine whether the combination of the questionnaires alone or with oximetry improves their predictive value for CPAP initiation. Read More

Sleep Breath 2018 Nov 19. Epub 2018 Nov 19.

Division of Endocrinology and Metabolism, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama 6 Road, Bangkok, 10400, Thailand.

Purpose: Hypothyroidism is associated with a high frequency of obstructive sleep apnea (OSA). However, the prevalence of OSA in hypothyroid patients is not different from the general population in many reports. The importance of thyroid function screening in sleep-disordered breathing is still controversial. Read More

Conf Proc IEEE Eng Med Biol Soc 2018 Jul;2018:457-460

Obstructive Sleep Apnea (OSA) is a common sleep disorder affecting $>10\%$ of the middle-aged population. The gold standard diagnostic procedure is the Polysomnography (PSG), which is both costly and time consuming. A simple and non-expensive screening therefore would be of great value. Read More

Conf Proc IEEE Eng Med Biol Soc 2018 Jul;2018:179-182

Obstructive Sleep Apnea (OSA) is the most common form of sleep-disordered breathing in children. The gold standard to screen for OSA, polysomnography (PSG), requires an overnight stay in the hospital and is resource intensive. The Phone Oximeter is a non-invasive smartphone-based tool to record pulse oximetry. Read More

Acta Clin Belg 2018 Nov 15:1-9. Epub 2018 Nov 15.

a Leuven University Centre for Sleep and Wake Disorders (LUCS) , University Hospitals Leuven , Leuven , Belgium.

Objectives: Last years, vibrating devices were introduced to treat positional sleep apnoea (POSA). However, few data exist on determinants of effectiveness and adherence in clinical settings.

Methods: The NightBalance Sleep Position Trainer (SPT) analyses the patient's position during the first 2 nights, starts to build up vibrations during the following 7 and is 100% performant from night 10 on; and, reports on %supine, usage time, number of (responses on) vibrations. Read More

J Altern Complement Med 2018 Nov 14. Epub 2018 Nov 14.

4 Department of Physical Therapy and Rehabilitation, Faculty of Health Sciences, Medipol University , Istanbul, Turkey .

Objectives: This study aims to investigate the effects of t'ai chi and qigong (TCQ) training on severity of obstructive sleep apnea (OSA).

Design: A prospective, 12-week, single-center, double-blinded, randomized controlled trial.

Setting: Sleep Disorders Center of Medical Faculty in Istanbul, Turkey. Read More

J Clin Sleep Med 2018 Nov 15;14(11):1859-1863. Epub 2018 Nov 15.

Sleep Unit, Heart and Lung Center, Helsinki University Hospital, University of Helsinki, Helsinki Finland.

Study Objectives: No consensus exists regarding monitoring the initiation of positive airway pressure (PAP) by oximetry. A PAP device report may be insufficient to ensure a good therapeutic response in all patients. This study aimed to identify patients who would potentially benefit from oximetry monitoring during PAP initiation. Read More

J Clin Sleep Med 2018 Nov 15;14(11):1889-1894. Epub 2018 Nov 15.

Baylor Scott and White Health, Central Division, Temple, Texas.

Study Objectives: A home sleep apnea test (HSAT) is an acceptable alternative to polysomnography (PSG) for the diagnosis of obstructive sleep apnea (OSA) in patients with high pretest probability without certain comorbidities, such as severe pulmonary disease, congestive heart failure, or neuromuscular weakness. Current guidelines recommend repeat in-laborataory PSG in those with an initial negative PSG and high clinical suspicion for OSA. This retrospective study evaluated predictors of OSA on HSAT in patients who had a negative PSG. Read More

Curr Diab Rep 2018 Oct 25;18(12):137. Epub 2018 Oct 25.

Endocrinology, Department of Systems Medicine, University of Rome Tor Vergata, Via Montpellier, 1, 00133, Rome, Italy.

Purpose Of Review: This review considers the relationship between abnormal blood pressure (BP) variability and autonomic dysfunction through an attempt to answer questions about its clinical relevance and pertinence to diabetes and cardiovascular autonomic neuropathy (CAN) and which therapeutic measures can lessen its cardiovascular impact.

Recent Findings: Office, ambulatory, and home BP monitoring identify posture-related, circadian, short-term, and long-term BP variabilities. Abnormal BP variability is a risk marker for organ damage, mortality, and cardiovascular events. Read More

Sleep 2018 Oct 22. Epub 2018 Oct 22.

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, MA.

Rationale: While short sleep duration has been linked to unhealthy dietary patterns, little is known about the association of obstructive sleep apnea (OSA), a disorder characterized by sleep fragmentation, and diet.

Objective: Investigate associations between diet quality and OSA in the Multi-Ethnic Study of Atherosclerosis and assess whether reductions in slow wave sleep (stage N3) and rapid eye movement (REM) sleep are potential mediators for these associations.

Methods: A diverse population (N = 1,813) completed a food frequency questionnaire and underwent Type 2 in-home polysomnography, which included measurement of N3 and REM sleep and apnea-hypopnea index (AHI). Read More

Sleep Breath 2018 Dec 11;22(4):1179-1188. Epub 2018 Oct 11.

Division of Pulmonary, Critical Care, and Sleep Medicine, New York University School of Medicine, New York, NY, USA.

Rationale: Home sleep apnea testing (HSAT) typically does not include electroencephalogram (EEG) monitoring for sleep assessment. In patients with insomnia and low sleep efficiency, overestimation of the sleep period can result from absence of EEG, which will reduce sleep disordered breathing (SDB) indices and may lead to a false-negative result.

Objective: To validate a single channel frontal EEG for scoring sleep versus wake against full EEG during polysomnography, and then to examine the utility of adding this single channel EEG to standard HSAT to prevent false-negative results. Read More

Paediatr Anaesth 2018 Nov 3;28(11):940-946. Epub 2018 Oct 3.

Department of Pulmonary Medicine, Sleep Disorders Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Sleep-disordered breathing has a prevalence of 12% in the pediatric population. It represents a spectrum of disorders encompassing abnormalities of the upper airway that lead to sleep disruption, including primary snoring, obstructive sleep apnea, central sleep apnea, and sleep-related hypoventilation. Sleep-disordered breathing is the most common indication for adenotonsillectomy, one of the most common procedures performed in children. Read More

J Clin Sleep Med 2018 Sep 15;14(9):1605-1620. Epub 2018 Sep 15.

Department of Otolaryngology-Head and Neck Surgery, Division of Sleep Surgery, Stanford University, Stanford, California.

Study Objectives: Sleep disorders in most individuals remain undiagnosed and without treatment. The use of novel tools and mobile technology has the potential to increase access to diagnosis. The objective of this study was to perform a quantitative and qualitative analysis of the available literature evaluating the accuracy of smartphones and portable devices to screen for sleep-disordered breathing (SDB). Read More

J Clin Sleep Med 2018 Sep 15;14(9):1495-1501. Epub 2018 Sep 15.

Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria.

Study Objectives: To study the feasibility and accuracy of home sleep apnea testing (HSAT) in the diagnosis of obstructive sleep apnea (OSA) in a stroke rehabilitation unit.

Methods: Stroke patients referred to a neurorehabilitation center underwent OSA screening by means of HSAT within the Home Polygraphic Recording with Telemedicine Monitoring for Diagnosis and Treatment of Sleep Apnea in Stroke, or HOPES study (ClinicalTrials.gov identifier: NCT02748681). Read More

Sleep Med Rev 2018 10 17;41:149-160. Epub 2018 Feb 17.

Charité Universitatsmedizin, Sleep Center, Germany; International Clinical Research Center, St. Anne's University Hospital Brno, Brno, Czech Republic.

One of the most common sleep-related disorders is obstructive sleep apnea, characterized by a reduction of airflow while breathing during sleep and cause significant health problems. This disorder is mainly diagnosed in sleep labs with polysomnography, involving high costs and stress for the patient. To address this situation multiple systems have been proposed to conduct the examination and analysis in the patient's home, using sensors to detect physiological signals that are examined by algorithms. Read More

Sleep Med 2018 Nov 10;51:80-84. Epub 2018 Aug 10.

Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Sweden.

Objective: Combined insomnia and obstructive sleep apnea has been the focus of considerable research with respect to its health effects. A related issue is whether sleep disturbances in combination with snoring might exert effects on objective sleep variables in the non-clinical general population. The purpose of the present study was to investigate the polysomnographical characteristics of individuals who had sought medical help for both disturbed sleep and for snoring. Read More

Sleep Med 2018 Oct 30;50:145-151. Epub 2018 May 30.

Advanced Brain Monitoring, Carlsbad, CA, USA.

Objective/background: Systematically compare four criteria for Positional Obstructive Sleep Apnea (POSA) based on AASM 2007 and 2012 hypopnea scoring definitions.

Patients/methods: 142 records acquired by in-home polysomnography (Sleep Profiler PSG2™) were retrospectively analyzed using AHI based on the American Academy Sleep Medicine 2007 and 2012 criteria (AHI and AHI). Positional obstructive sleep apnea (POSA) was characterized using four criteria: Amsterdam Positional OSA Classification (APOC), supine AHI twice the non-supine AHI (Cartwright), Cartwright plus the non-supine AHI < 5 (Mador), and the overall AHI severity at least 1. Read More

Sleep Breath 2018 Jul 18. Epub 2018 Jul 18.

Resonea Inc., 11445 E Via Linda, Suite 2 # 224, Scottsdale, AZ, 85259, USA.

Purpose: Diagnosis of obstructive sleep apnea by the gold-standard of polysomnography (PSG), or by home sleep testing (HST), requires numerous physical connections to the patient which may restrict use of these tools for early screening. We hypothesized that normal and disturbed breathing may be detected by a consumer smartphone without physical connections to the patient using novel algorithms to analyze ambient sound.

Methods: We studied 91 patients undergoing clinically indicated PSG. Read More

Cureus 2018 May 8;10(5):e2593. Epub 2018 May 8.

Bariatric Surgery, University of north dakota.

Background Obstructive sleep apnea (OSA) is a common sleep disorder, especially in patients with obesity. Bariatric surgery is an effective tool to reduce weight and treat co-morbid diseases in patients with morbid obesity. One of these disorders is OSA. Read More

IEEE Trans Biomed Circuits Syst 2018 08 7;12(4):762-773. Epub 2018 May 7.

Obstructive Sleep Apnea (OSA) is one of the main under-diagnosed sleep disorder. It is an aggravating factor for several serious cardiovascular diseases, including stroke. There is, however, a lack of medical devices for long-term ambulatory monitoring of OSA since current systems are rather bulky, expensive, intrusive, and cannot be used for long-term monitoring in ambulatory settings. Read More

IEEE J Biomed Health Inform 2018 Apr 4. Epub 2018 Apr 4.

Sleep disorders are a common health condition that can affect numerous aspects of life. Obstructive sleep apnea is one of the most common disorders and is characterized by a reduction or cessation of airflow during sleep. In many countries this disorder is usually diagnosed in sleep laboratories, by a polysomnography, which is an expensive procedure involving much effort for the patient. Read More

IEEE J Biomed Health Inform 2018 Jun 1. Epub 2018 Jun 1.

Obstructive Sleep Apnea (OSA) is a prevalent sleep disorder, and highly affects the quality of human life. Currently, gold standard for OSA detection is Polysomnogram. Since this method is time consuming and cost inefficient, practical systems focus on the usage of electrocardiogram (ECG) signals for OSA detection. Read More

J Clin Sleep Med 2018 Jul 15;14(7):1245-1247. Epub 2018 Jul 15.

Division of Sleep Medicine, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

Abstract: The diagnostic criteria for obstructive sleep apnea (OSA) in adults, as defined in the International Classification of Sleep Disorders, Third Edition, requires an increased frequency of obstructive respiratory events demonstrated by in-laboratory, attended polysomnography (PSG) or a home sleep apnea test (HSAT). However, there are currently two hypopnea scoring criteria in The AASM Manual for the Scoring of Sleep and Associated Events: Rules, Terminology and Technical Specifications (AASM Scoring Manual). This dichotomy results in differences among laboratory reports, patient treatments and payer policies. Read More

Chest 2019 Jan 5;155(1):227-233. Epub 2018 Jul 5.

Division of Pulmonary, Critical Care, Allergy and Immunology, Department of Medicine, Northshore University Health System, Evanston, IL. Electronic address:

As the cost of health care continues to escalate, payers are adapting by moving away from models based on traditional fee-for-service reimbursement to models focused on rewarding care delivery that reduces costs and improves quality. These alternative payment models (APMs) are being introduced by government and commercial payers and will likely become the norm over time. Recent changes in sleep medicine related to advances in technology and approaches by payers for the management of OSA make this an appropriate time to incorporate the delivery of sleep medicine services into APMs. Read More

Sleep Disord 2018 3;2018:2394146. Epub 2018 Jun 3.

Department of Psychiatry, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, ON, Canada.

Introduction: Obstructive sleep apnea (OSA) is common and usually underdetected in patients with cardiac arrhythmia. Ambulatory sleep testing may provide an alternative method for detection of OSA under realistic conditions compared to in-laboratory polysomnography. We aimed to (1) determine the sleep architecture in arrhythmia patients; (2) detect differences in sleep parameters between patients with and without OSA; and (3) compare the results of two consecutive nights of unattended ambulatory sleep testing. Read More

Sleep Med 2018 Aug 9;48:157-162. Epub 2018 Mar 9.

Center for Investigation and Research in Sleep, University Hospital of Lausanne (CHUV), Rue du Bugnon 46, 1011, Lausanne, Switzerland.

Objective/background: To determine the prevalence of positional obstructive sleep apnea (POSA) and exclusive POSA (ePOSA) in the general population and to assess the factors independently associated with POSA and ePOSA according to gender and menopausal status.

Patients/methods: Participants of the population-based HypnoLaus Sleep Cohort underwent full polysomnography at home. POSA was defined as an apnea-hypopnea index (AHI) ≥5/h, and supine/non-supine AHI ratio (sAHI/nsAHI) ≥2 (ePOSA when non-supine AHI was normalized). Read More

Sleep Breath 2018 Dec 29;22(4):1153-1160. Epub 2018 Jun 29.

Interdiscplinary Center for Sleep Medicine, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.

Background: OSA-patients with persistent excessive daytime sleepiness (EDS) despite CPAP treatment are challenging in daily clinical life. To rule out residual sleep-disordered breathing (SDB), CPAP device-derived data are used in outpatient setting. In case of no pathological finding, a more intensive work-up with is necessary. Read More

J Clin Sleep Med 2018 Jun 15;14(6):991-1003. Epub 2018 Jun 15.

Sleep Disorders Centre, Department of Respiratory and Sleep Medicine, Princess Alexandra Hospital, Woolloongabba, Australia.

Study Objectives: Severities of obstructive sleep apnea (OSA) estimated both for the overall sleep duration and for the time spent in rapid eye movement (REM) and non-rapid eye movement (NREM) sleep are important in managing the disease. The objective of this study is to investigate a method by which snore sounds can be analyzed to detect the presence of OSA in NREM and REM sleep.

Methods: Using bedside microphones, snoring and breathing-related sounds were acquired from 91 patients with OSA (35 females and 56 males) undergoing routine diagnostic polysomnography studies. Read More

PLoS One 2018 30;13(5):e0198315. Epub 2018 May 30.

Faculty of Medicine, University of Basel, Basel, Switzerland.

Background: Obstructive sleep apnea syndrome (OSAS) is common in adults. People with OSAS have a higher risk of experiencing traffic accidents and occupational injuries (OIs). We aimed to clarify the diagnostic performance of a three-channel screening device (ApneaLinkTM) compared with the gold standard of full-night attended polysomnography (PSG) among hospital outpatients not referred for sleep-related symptoms. Read More

Sleep Sci 2018 Jan-Feb;11(1):45-48

Hospital Alemán.

According to recent reports, sleep disorders affect 30% of the adult population and 5-10% of children. Obstructive Sleep Apnea Hypopnea Syndrome (OSA) has a considerable epidemiological impact and demand for consultation is growing in our community. Therefore, it is necessary to know the principles of interpretation of diagnostic methods. Read More

Sleep Sci 2018 Jan-Feb;11(1):12-19

Hospital de Carabineros (HOSCAR), Neurphysiology Unit - Santiago - RM - Chile.

Objective: This study uses polysomnography and the Epworth sleepiness scale to assess the efficiency of the OcluchMAD in patients with Obstructive sleep apnea-hypopnea syndrome (OSAS), on overall respiratory disturbance indices (RDI), supine respiratory disturbance index (SRDI), minimum oxygen saturation, microarousals, CT90 (or ID90), sleep efficacy and snoring. These data are associated with skeletal class and facial biotype in order to establish predictive parameters for its effectiveness according to craniofacial morphology.

Methods: 22 adult patients (between 38 and 60 years of age) of both sexes (7 women, 15 men) diagnosed with OSAS in the Hospital de Carabineros de Chile (HOSCAR) Neurology Unit were recruited and given the Ocluch MAD in the hospital's dental clinic, for its use during a three-month period. Read More

Diabet Med 2018 10 24;35(10):1391-1398. Epub 2018 May 24.

Nordsjaellands University Hospital, Hilleroed, Denmark.

Aims: To examine whether people with Type 2 diabetes with concurrent obstructive sleep apnoea have increased arterial stiffness as compared with people with Type 2 diabetes without obstructive sleep apnoea.

Methods: In a study with a case-control design, 40 people with Type 2 diabetes and treatment-naïve moderate to severe obstructive sleep apnoea (Apnoea-Hypopnoea Index ≥15) and a control group of 31 people with Type 2 diabetes without obstructive sleep apnoea (Apnoea-Hypopnoea Index <5) were examined. Obstructive sleep apnoea status was evaluated using the ApneaLink + home-monitoring device (Resmed Inc. Read More

Am Fam Physician 2018 May;97(9):581-588

McGill University, Montreal, Quebec, Canada.

Based on systematic surveillance of more than 110 medical journals, 247 studies met criteria as POEMs (patient-oriented evidence that matters) in 2017. Members of the Canadian Medical Association identified 20 of these POEMs as most relevant to practice. This article reviews the clinical questions and bottom-line answers from these studies. Read More

J Pediatr 2018 Jul 8;198:67-75.e1. Epub 2018 May 8.

Section of Gastroenterology, Hepatology, and Nutrition, Department of Pediatrics and the Digestive Health Institute, Children's Hospital Colorado and University of Colorado School of Medicine, Aurora, CO.

Objective: To determine the effects of treating obstructive sleep apnea/nocturnal hypoxia on pediatric nonalcoholic fatty liver disease (NAFLD) severity and oxidative stress.

Study Design: Biopsy proven participants (n = 9) with NAFLD and obstructive sleep apnea/hypoxia were studied before and after treatment with continuous positive airway pressure (CPAP) for sleep disordered breathing, including laboratory testing and markers of oxidative stress, urine F(2)-isoprostanes.

Results: Adolescents (age 11. Read More

Blood Press Monit 2018 Aug;23(4):175-184

Department of Sleep Medicine Center, NanFang Hospital, Southern Medical University.

Background: Obstructive sleep apnea-hypopnea syndrome (OSAHS) is common in people with hypertension and cardiac rhythm disorder. The objectives of this study were to determine the effect of short-term continuous positive airway pressure (CPAP) on blood pressure (BP) and cardiac rhythm in Chinese patients with moderate to severe OSAHS.

Patients And Methods: Eligible patients in the two hospitals were consecutively enrolled into the prospective study. Read More

J Am Geriatr Soc 2018 Jul 9;66(7):1296-1302. Epub 2018 May 9.

Department of Neurology, School of Public Health, University of Michigan, Ann Arbor, Michigan.

Objectives: To estimate the proportion of older Americans at risk for obstructive sleep apnea (OSA) who receive OSA evaluations, diagnosis, and treatment.

Design: Cross sectional study.

Setting: National Health and Aging Trends Study (NHATS), Round 3 survey. Read More

Sleep 2018 Aug;41(8)

Sleep Apnea Patient-Centered Outcomes Network.

Study Objectives: Home sleep apnea testing (HSAT) is increasingly used as an alternative to laboratory-based polysomnography (PSG) for the diagnosis of obstructive sleep apnea. Patient satisfaction with sleep testing performed at home or in the lab has been sparsely assessed, despite its potentially pivotal role in determining patients' acceptance of sleep apnea treatment. We hypothesize that satisfaction in clinical practice may differ from what has been previously reported within the research setting. Read More

J Clin Sleep Med 2018 May 15;14(5):819-828. Epub 2018 May 15.

Respiratory Epidemiology and Clinical Research Unit, Research Institute of the McGill University Health Centre - Montreal, Quebec, Canada.

Study Objectives: Parkinson disease (PD) non-motor symptoms are associated with sleep disorders and impair quality of life. Our objective was to assess the effect of obstructive sleep apnea (OSA) treatment using continuous positive airway pressure (CPAP) on PD non-motor symptoms.

Methods: In this prospective observational study, 67 patients with idiopathic PD underwent polysomnography. Read More

Sleep Breath 2018 Apr 23. Epub 2018 Apr 23.

Department of Experimental, Diagnostic and Speciality Medicine (DIMES), Alma Mater Studiorum Università di Bologna, Viale Berti Pichat 5, 40126, Bologna, Italy.

Smartphone applications are considered as the prime candidate for the purposes of large-scale, low-cost and long-term sleep monitoring. How reliable and scientifically grounded is smartphone-based assessment of healthy and disturbed sleep remains a key issue in this direction. Here we offer a review of validation studies of sleep applications to the aim of providing some guidance in terms of their reliability to assess sleep in healthy and clinical populations, and stimulating further examination of their potential for clinical use and improved sleep hygiene. Read More

Otolaryngol Head Neck Surg 2018 Jul 10;159(1):166-172. Epub 2018 Apr 10.

1 Department of Otorhinolaryngology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Objective To assess the accuracy and clinical reliability of watch peripheral arterial tonometry (PAT) compared with polysomnography (PSG) for the diagnosis of pediatric obstructive sleep apnea (OSA). Study Design Prospective, diagnostic test study. Setting National tertiary referral hospital. Read More

J Clin Sleep Med 2018 Apr 15;14(4):631-639. Epub 2018 Apr 15.

Mayo Clinic Center for Sleep Medicine, Mayo Clinic, Rochester, Minnesota.

Study Objectives: Health care complexity includes dimensions of patient comorbidity and the level of services needed to meet patient demands. Home sleep apnea tests (HSAT) are increasingly used to test medically uncomplicated patients suspected of having moderate to severe obstructive sleep apnea (OSA). Patients with significant comorbidities or other sleep disorders are not candidates for HSAT and require attended in-center polysomnography. Read More