Search Our Scientific Publications & Authors

J Am Soc Nephrol 2020 Jun 26. Epub 2020 Jun 26.

Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota.

Background: Obstructive sleep apnea may be associated with development of CKD through hypoxia, inflammation, and oxidative stress. Individuals with this sleep disorder are also at increased risk for established CKD risk factors, including obesity, hypertension, and type 2 diabetes.

Methods: We examined the association between obstructive sleep apnea, other sleep characteristics, and risk of incident CKD (stage 3 or higher) in 1525 participants (mean age, 62. Read More

J Res Med Sci 2020 13;25:42. Epub 2020 Apr 13.

Department of Pulmonology, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, România.

Background: Obstructive sleep apnea (OSA) can lead to cardiac complications: brady and tachyarrhythmias and sudden cardiac death. Continuous positive airway pressure (CPAP) is the gold standard for the treatment of OSA. The present study aims to demonstrate the efficiency of CPAP in the treatment of cardiac arrhythmias in patients with OSA. Read More

Am J Otolaryngol 2020 Jun 1;41(5):102589. Epub 2020 Jun 1.

Department of ENT, Azienda USL Toscana Sud Est, Ospedale Misericordia, Grosseto, Italy.

Purpose: Snoring is a very common disorder, but, at present, there is no universally accepted classification for the condition. The main aim of this paper is to introduce a home sleep monitoring-based classification of common snoring patterns in simple snorers and in patients with obstructive sleep apnea-hypopnea syndrome (OSAHS).

Materials And Methods: In total, 561 consecutive patients with a history of snoring, either simple or associated with apnea, were enrolled in this home sleep monitoring study. Read More

Physiol Meas 2020 Jun 19. Epub 2020 Jun 19.

Department of Otolaryngology Head and Neck Surgery & Center of Sleep Medicine, Xi'an Jiaotong University Second Affiliated Hospital, Xi'an, Shaanxi, CHINA.

Objective: Polysomnography is typically used to evaluate the severity of obstructive sleep apnea (OSA) but inconvenience of application and high cost considerably affect the diagnostics. In this study, sleeping sound signals are used to detect OSA in patients.

Approach: A deep feature transfer-based OSA detection approach is proposed. Read More

J Clin Sleep Med 2020 Jun 9. Epub 2020 Jun 9.

Emory University School of Medicine, Atlanta, Georgia.

Study Objectives: Peripheral arterial tonometry (PAT) based technology represents a validated portable monitoring modality for diagnosis of obstructive sleep apnea (OSA). We assessed the diagnostic accuracy of PAT-based technology in a large point-of-care cohort of patients studied with concurrent polysomnography (PSG).

Methods: During study enrollment, all participants suspected to have OSA and tested by in-laboratory PSG underwent concurrent PAT device recordings. Read More

Otolaryngol Head Neck Surg 2020 Jun 9:194599820931087. Epub 2020 Jun 9.

Tripler Army Medical Center, Tripler AMC, Hawaii, USA.

Objective: To systematically review the international literature for studies evaluating the effect of alcohol consumption on the occurrence and severity of snoring and obstructive sleep apnea and to use the available data to perform a meta-analysis.

Data Sources: MEDLINE, Embase, The Cochrane Library, CINAHL/EBASCO, and Scopus.

Review Methods: The protocol was registered in PROSPERO in March 2018. Read More

J Clin Sleep Med 2020 Jun 5. Epub 2020 Jun 5.

Sleep Centre, Foothills Medical Centre, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

Study Objectives: Home sleep apnea testing (HSAT) is commonly used to diagnose obstructive sleep apnea (OSA), but its role in identifying patients with suspected hypoventilation or predicting their response to continuous positive airway pressure (CPAP) therapy has not been assessed. The primary objective was to determine if HSAT, combined with clinical variables, could predict the failure of CPAP to correct nocturnal hypoxemia during polysomnography (PSG) in a population with suspected hypoventilation. Secondary objectives were to determine if HSAT and clinical parameters could predict awake or sleep hypoventilation. Read More

Am J Hypertens 2020 Jun 3. Epub 2020 Jun 3.

Brigham and Women's Hospital, Boston, MA.

Background: Obstructive sleep apnea (OSA), nocturnal hypertension, and non-dipping systolic blood pressure (BP) are each highly prevalent among African Americans. However, few data are available on the association between OSA and nighttime BP in this population.

Methods: We examined the association of OSA with nighttime BP among African Americans who completed 24-hour ambulatory BP monitoring at Exam 1 (2000-2004) of the Jackson Heart Study (JHS) and subsequently participated in the JHS Sleep Study (2012-2016). Read More

J Sci Med Sport 2020 Apr 18. Epub 2020 Apr 18.

School of Human Movement and Nutrition Sciences, University of Queensland, Australia; School of Exercise and Nutrition Sciences, Queensland University of Technology, Australia. Electronic address:

Objectives: To explore the prevalence of obstructive sleep apnea (OSA) within a professional rugby league team and determine associations of OSA with ethnicity, positional group, and physical characteristics.

Design: Observational prospective cohort study.

Methods: Twenty-two professional rugby league athletes underwent one night of home-based polysomnography with apnea-hypopnea index (AHI), rapid eye movement (REM), non-REM and supine determined to indicate OSA. Read More

Sleep Breath 2020 May 16. Epub 2020 May 16.

Division of Otolaryngology - Head and Neck Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Purpose: Little is known regarding the influence of in-laboratory polysomnography (PSG) equipment on sleep position, especially on the prevalence of supine positioning, which in many cases may lead to a more severe sleep apnea diagnosis. The aim of this study was to assess the percentage of supine sleep during an in-laboratory PSG compared to that seen during a home sleep apnea test (HSAT).

Methods: This was a retrospective cohort study comparing in-laboratory PSG and HSAT using a peripheral arterial tone (PAT) technology device. Read More

Sleep Breath 2020 May 13. Epub 2020 May 13.

LHL-sykehuset, Ragnar Strømsv. 10, 2067, Jessheim, Norway.

Purpose: An increase in PaCO is the element that defines sleep hypoventilation (SH). We queried if patients with SH, and those with PaCO increases during sleep for shorter time periods than SH (shamSH) differed from the patients without SH (noSH) in other ways.

Methods: This was a retrospective re-analysis of data from 100 stable inpatients with COPD with and without chronic hypercapnic respiratory failure. Read More

Eur J Endocrinol 2020 Jul;183(1):31-39

Department of Endocrinology and Metabolism, Royal Adelaide Hospital, Adelaide, South Australia, Australia.

Objective: Obstructive sleep apnea (OSA) is generally considered to lower serum testosterone concentration in men, although data supporting this as a direct effect are limited. The aim of this study was to determine the relationship between the presence and severity of OSA and testosterone in a community-based cohort of men aged over 40 years.

Design And Methods: Anthropometry, polysomnography and biomedical information were collected from enrolled, consenting men from the prospective, longitudinal MAILES study cohort. Read More

Otolaryngol Clin North Am 2020 Jun 23;53(3):367-383. Epub 2020 Apr 23.

Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Place, Box 1232, New York, NY 10029, USA.

Obstructive sleep apnea is a common, but under-recognized, condition. Polysomnography remains the gold standard for diagnosing obstructive sleep apnea and determining whether treatment is appropriate. The development of home sleep apnea testing has allowed for a faster and more convenient method of diagnosis. Read More

Ir J Psychol Med 2020 Apr 24:1-7. Epub 2020 Apr 24.

Adelaide Medical School, Adelaide University, 4 North Terrace, Adelaide, South Australia, Australia.

Objectives: We aimed to assess the incidence of obstructive sleep apnoea (OSA) in people with schizophrenia, to explore clinical associates with OSA and how well OSA screening tools perform in this population.

Methods: All patients registered in a community outpatient Clozapine clinic, between January 2014 and March 2016, were consecutively approached to participate. Participants were screened for OSA using at home multichannel polysomnography (PSG) and were diagnosed with OSA if the apnoea-hypopnoea index (AHI) was >10 events/hr. Read More

J Clin Sleep Med 2020 Apr 13. Epub 2020 Apr 13.

Sleep Unit, Department of Respiratory Diseases, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain.

Study Objectives: Involvement of primary care teams in the care of patients with obstructive sleep apnea (OSA) is a focus of interest. The study objective was to compare diagnostic and therapeutic agreement between decisions taken by primary care professionals and sleep unit specialists.

Methods: Prospective multicenter study, setting at primary care and specialized care in the urban area of Barcelona, Spain. Read More

Prog Cardiovasc Dis 2020 Apr 8. Epub 2020 Apr 8.

Saint Luke's Mid America Heart Institute, Kansas City, MO, USA.

The presence of hypertension (HTN) in patients with diabetes mellitus (DM) further worsens cardiovascular disease (CVD) prognosis. In addition, masked HTN and abnormal circadian blood pressure (BP) variability are common among patients with DM. Clinical trial data show that sodium-glucose cotransporter 2 inhibitors (SGLT2i) improve CVD prognosis and prevent progression of renal dysfunction in high-risk patients with type 2 DM (T2DM). Read More

Physiol Meas 2020 05 12;41(4):044007. Epub 2020 May 12.

Faculty of Biomedical Engineering, Technion, Israel Institute of Technology, Haifa, Israel.

Objective: Portable oximetry has been shown to be a promising candidate for large-scale obstructive sleep apnea screening. In polysomnography (PSG), the gold standard OSA diagnosis test, the oxygen desaturation index (ODI) is usually computed from desaturation events occurring during sleep periods only, i.e. Read More

Maturitas 2020 May 11;135:1-5. Epub 2020 Feb 11.

Division of General Internal Medicine, Mayo Clinic, Rochester, MN, United States; Division of Endocrinology, Metabolism and Nutrition, Mayo Clinic, Rochester, MN, United States. Electronic address:

Objectives: The STOP-BANG questionnaire (snoring, tiredness, observed apneas, high blood pressure, body mass index, age, neck size, gender) was originally validated to screen for obstructive sleep apnea (OSA) in the surgical population. It has been validated in mixed populations of men and women. We aimed to evaluate its reliability for OSA screening of midlife women. Read More

Sleep Breath 2020 Mar 28. Epub 2020 Mar 28.

MyCardio LLC, SleepImage®, 3513 Brighton Blvd, Denver, CO, 80216, USA.

Objective: Sleep quality is vital for healthy development in children. Sleep disorders are prevalent and negatively affect sleep quality. Early identification and appropriate intervention can improve children's health and quality of life. Read More

Sci Rep 2020 Mar 24;10(1):5332. Epub 2020 Mar 24.

Pneumology Department, Río Hortega University Hospital, Valladolid, Spain.

The most appropriate physiological signals to develop simplified as well as accurate screening tests for obstructive sleep apnoea (OSA) remain unknown. This study aimed at assessing whether joint analysis of at-home oximetry and airflow recordings by means of machine-learning algorithms leads to a significant diagnostic performance increase compared to single-channel approaches. Consecutive patients showing moderate-to-high clinical suspicion of OSA were involved. Read More

Ther Adv Endocrinol Metab 2020 21;11:2042018820906689. Epub 2020 Feb 21.

Warwickshire Institute for the Study of Diabetes, Endocrinology and Metabolism (WISDEM) and Human Metabolism Research Unit (HMRU), University Hospitals Coventry and Warwickshire NHS Trust, Coventry, CV2 2DX, UK.

Background: Obstructive sleep apnoea (OSA) and polycystic ovary syndrome (PCOS) are associated with significant comorbidities and commonly coexist. The primary aim of this study was to examine the relationship between OSA and quality of life (QoL) in women with PCOS.

Methods: We conducted an observational cross-sectional study. Read More

Laryngoscope 2020 Feb 28. Epub 2020 Feb 28.

Division of Sleep Surgery, Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, U.S.A.

Objectives/hypothesis: Hypoglossal nerve stimulation (HGNS) effectively treats obstructive sleep apnea in select patients. Drug-induced sleep endoscopy (DISE) is required for HGNS candidacy. Data suggest that mandibular advancement (MA) devices and HGNS share similar target populations. Read More

Stroke 2020 Apr 11;51(4):1294-1296. Epub 2020 Feb 11.

From the Department of Medicine, Division of Neurology, Sunnybrook Health Sciences Centre, University of Toronto, Canada; and Hurvitz Brain Sciences Research Program, Sunnybrook Research Institute, Sunnybrook Health Sciences Centre, Toronto, Canada.

Background and Purpose- Compared with other causes of ischemic stroke, the mechanism of action of embolic stroke of undetermined source (ESUS) remains unclear, with previous literature suggesting that ESUS may be due to an undetected cardioembolic source. This study aimed to improve our understanding of the pathophysiology of ESUS through current knowledge of sleep disorders. Methods- Patients were included in this study if they sustained an ischemic stroke and completed either polysomnography or a home sleep apnea test. Read More

Adv Exp Med Biol 2020 ;1271:107-112

Department of Anthropology, Biology Institute, Wrocław University of Environmental and Life Sciences, Wrocław, Poland.

Polysomnography, a gold standard for the diagnosis of sleep-disordered breathing, is a complex investigation requiring access to the sleep laboratory. Thus, sleep-disordered breathing could be underdiagnosed. The aim of this paper was to investigate the feasibility and effectiveness of self-performed investigation of obstructive sleep apnea (OSA) in the home setting, using a portable device, and to assess the comfort and simplicity of the procedure from the patient's perspective. Read More

J Clin Sleep Med 2020 Feb 14. Epub 2020 Feb 14.

Service Epilepsie, Sommeil, Explorations Fonctionnelles Neurologiques Pédiatriques, Hôpital Femme Mère Enfant, Hospices Civils de Lyon, Bron, France.

Study Objectives: Due to a limited number of pediatric sleep centers, the aim was to test the feasibility of ambulatory polysomnography (PSG-home) in a group of French children suspected of obstructive sleep apnea (OSA).

Methods: Children undergoing one-night PSG-home, with device installed at the pediatric sleep physician's office, were prospectively included. General failure was considered when PSG-home recording captured <5 h of artifact-free sleep or when ≥1 channel (nasal flow, thoraco-abdominal belts, oximetry) presented artifacts >75% of the recording time. Read More

ERJ Open Res 2020 Jan 10;6(1). Epub 2020 Feb 10.

Laboratori del Son, Servei de Pneumologia, Hospital Clínic, Barcelona, Spain.

Background: Current continuous positive airway pressure (CPAP) devices can be monitored remotely; however, in-person visits are kept for clinical follow-up in order to promote CPAP use and resolve potential side-effects. Mobile health is a promising way to provide remote and easy clinical control for CPAP follow-up and support. We aimed to evaluate the feasibility and acceptance by obstructive sleep apnoea (OSA) patients and healthcare professionals of a newly designed mobile app (Appnea-Q) to promote clinical control through a self-monitoring tool for patients with CPAP supervised by sleep professionals. Read More

Int J Environ Res Public Health 2020 02 10;17(3). Epub 2020 Feb 10.

Department of Head-Neck Surgery, Otolaryngology, Head-Neck and Oral Surgery Unit, Morgagni Pierantoni Hospital, Via Carlo Forlanini, 34, 47121 Forlì, Italy.

The purpose of this study was to evaluate the prevalence of position-dependent obstructive sleep apnea (POSA) in elderly patients (≥65 years old). Adult (range 19-65 years old) and elderly patients were also compared in order to show differences in the incidence of POSA between these two groups of patients. A prospective bi-center study was performed between January 2018 and May 2019. Read More

Sensors (Basel) 2020 Feb 7;20(3). Epub 2020 Feb 7.

ITI/Larsys/Madeira Interactive Technologies Institute, 9020-105 Funchal, Portugal.

Sleep related disorders can severely disturb the quality of sleep. Among these disorders, obstructive sleep apnea (OSA) is highly prevalent and commonly undiagnosed. Polysomnography is considered to be the gold standard exam for OSA diagnosis. Read More

Pediatr Int 2020 Feb 8. Epub 2020 Feb 8.

Department of Pulmonology, Faculty of Heath Sciences, University of Warmia and Mazury in Olsztyn, Jagiellońska 78, 10-357, Olsztyn, Poland.

Background: The most common respiratory disturbance in sleeping children is the Obstructive Sleep Apnea Syndrome. The passive smoking is mentioned one of factors predisposing to Obstructive Sleep Apnea Syndrome. Determination of correlations between exposure to tobacco smoke (passive smoking) and development of respiratory disorders in children during sleep. Read More

Respir Res 2020 Feb 4;21(1):42. Epub 2020 Feb 4.

Translational Research Unit, Hospital Universitario Miguel Servet, IIS Aragón, Zaragoza, Spain and CIBER Enfermedades Respiratorias, Madrid, Spain.

Background: Obstructive sleep apnoea (OSA) and morbid obesity (MO), defined by a body mass index ≥35 kg/m, are two closely related conditions. Recent studies suggest that circulating microRNA (miRNA) plays a potential role in the physiopathology of both conditions. To date, circulating miRNA expression has been studied separately in both conditions, but never jointly. Read More

Arch Bronconeumol 2020 Jan 30. Epub 2020 Jan 30.

Hospital Universitari Germans Trias i Pujol, Department of Respiratory Medicine, Badalona, Barcelona, Spain; Universitat Autònoma de Barcelona, Department of Medicine, Barcelona, Catalunya, Spain; Fundació Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol (IGTP), Department of Respiratory Medicine, Badalona, Catalunya, Spain; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERESP), Department of Respiratory Medicine, Barcelona, Catalunya, Spain.

Study Objectives: To evaluate the diagnostic accuracy of a non-invasive technology based on image processing for the identification of obstructive sleep apnea (OSA) and its severity at patients' home.

Methods: Observational, prospective, diagnostic accuracy study to evaluate the degree of measure agreement between Sleepwise (SW), in-laboratory attended polysomnography (PSG) and a home sleep apnea test (HSAT). 38 consecutive subjects with suspected OSA referred as outpatients to the sleep unit were recruited from September 2016 to September 2017. Read More

Respiration 2020;99(2):132-139. Epub 2020 Jan 29.

Centre de Recherche, Institut Universitaire de Cardiologie et de Pneumologie de Québec, Université Laval, Québec, Québec, Canada,

Background: Chronic obstructive pulmonary disease (COPD) and sleep apnea are common conditions and often coexist. The proper diagnosis of sleep apnea may affect the management and outcome of patients with COPD.

Objective: To determine the accuracy of home nocturnal oximetry to distinguish between nocturnal oxygen desaturation related to COPD alone or to sleep apnea in patients with moderate-to-severe COPD who have significant nocturnal hypoxemia with cyclical changes in saturation. Read More

J Clin Sleep Med 2020 Feb 13;16(2):279-283. Epub 2020 Jan 13.

VA Puget Sound Health Care System, Seattle, Washington.

Study Objectives: Incorporating registered nurses (RN-level) into obstructive sleep apnea (OSA) management decisions has the potential to augment the workforce and improve patient access, but the appropriateness of such task-shifting in typical practice is unclear.

Methods: Our medical center piloted a nurse triage program for sleep medicine referrals. Using a sleep specialist-designed decision-making tool, nurses triaged patients referred for initial sleep studies to either home sleep apnea test (HSAT) or in-laboratory polysomnography (PSG). Read More

J Clin Sleep Med 2020 Feb 13;16(2):319-323. Epub 2020 Jan 13.

Charité-Universitätsmedizin Berlin, CCM-CC11, Centre for Sleep Medicine.

None: Night-to-night variability (NNV) of the degree of obstructive sleep apnea (OSA) over the long term is not well investigated. In our case, we investigated the NNV of the apnea-hypopnea index (AHI) with regard to sleep structure. Unattended polysomnography (PSG) at home was used to determine the AHI in the course of 4 weeks in a single patient with a mild-to-moderate OSA, by using the Somnocheck R&K system. Read More

J Clin Sleep Med 2020 Feb 13;16(2):199-206. Epub 2020 Jan 13.

Program in Medical Sciences, School of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS, Brazil.

Study Objectives: The accuracy of obstructive sleep apnea (OSA) screening instruments in seniors may change as the predictive role of sex, age, and body mass index (BMI) changes with aging. We investigated the diagnostic performance of the STOP-BANG questionnaire in older individuals with aging-adapted scores and thresholds.

Methods: Independent community-dwelling adults aged 65 years or older were screened for OSA. Read More

J Clin Sleep Med 2020 Mar 14;16(3):353-359. Epub 2020 Jan 14.

Department of Oral and Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Study Objectives: Obstructive sleep apnea (OSA) is a sleep-related breathing disorder, commonly managed by either continuous positive airway pressure (CPAP) or a mandibular advancement device (MAD). Long-term follow-up and comparison regarding efficacy of these therapies is scarce. In this study the results of treatment, patient adherence, and satisfaction over a 10-year follow-up of these therapies are reported. Read More

Conf Proc IEEE Eng Med Biol Soc 2019 07;2019:4990-4993

Obstructive sleep apnea (OSA) is a common disorder with a low diagnosis ratio, leaving many patients undiagnosed and untreated. In the last decades, accelerometry has been found to be a feasible solution to obtain respiratory activity and a potential tool to monitor OSA. On the other hand, many smartphone-based systems have already been developed to propose solutions for OSA monitoring and treatment. Read More

Conf Proc IEEE Eng Med Biol Soc 2019 07;2019:4982-4985

Obstructive sleep apnea (OSA) is a prevalent disease, but most patients remain undiagnosed and untreated. Recently, mHealth tools are being proposed to screen OSA patients at home. In this work, we analyzed full-night audio signals recorded with a smartphone microphone. Read More

Conf Proc IEEE Eng Med Biol Soc 2019 07;2019:4301-4305

Medical devices used in a home setting for treating a variety of chronic diseases lack the ability to convey meaningful information to the patients directly about how they are engaging with their devices in real-time. This research is focused on the development of a monitoring system that addresses this need. For this initial design and testing, the research team applied the technology to a positive airway pressure (PAP) system used in the treatment of those suffering from obstructive sleep apnea (OSA). Read More

Conf Proc IEEE Eng Med Biol Soc 2019 Jul;2019:4233-4236

Obstructive sleep apnea (OSA) is characterized by upper airway obstructions known as apnea/hypopnea events. Narrowing of the upper airway during or near the vicinity of apnea/hypopnea causes the spectrum of the snores to shift to higher frequencies. Using an instrumentation quality wideband (WB) microphone (4Hz-100kHz), we previously demonstrated that potentially diagnostically useful frequency shifts could be detected even in regions beyond the human hearing range. Read More

Conf Proc IEEE Eng Med Biol Soc 2019 07;2019:2572-2575

Obstructive Sleep Apnea (OSA) is recognized as an increasing health risk, leading to daytime sleepiness and various medical conditions, such as hypertension and heart failure. Polysomnography (PSG), the gold standard to diagnose OSA, is a resource-intensive and expensive investigation confined to the hospital.Portable home monitoring, i. Read More

Intern Med J 2020 Jan 6. Epub 2020 Jan 6.

Thoracic and Sleep Medicine, The Prince Charles Hospital, Chermside, Queensland, Australia.

Background: A major impediment to provision of obstructive sleep apnoea (OSA) treatment is reliance on labour-intensive and costly laboratory-based polysomnography (PSG). This study investigated if measurement of oximetry and nasal flow via the ApneaLink™ device (AL) could identify patients with moderate-severe OSA among those referred for PSG to a tertiary sleep service.

Methods: New referrals to The Prince Charles Hospital Sleep Disorders Centre were assessed for suitability. Read More

Br J Surg 2020 01;107(2):e39-e55

Department of Surgical, Oncological and Gastroenterological Sciences, Section of Surgery, University of Padua, Padua, Italy.

Background: Obesity has become an increasing problem worldwide during the past few decades. Hence, surgeons and anaesthetists will care for an increasing number of obese patients in the foreseeable future, and should be prepared to provide optimal management for these individuals. This review provides an update of recent evidence regarding perioperative strategies for obese patients. Read More

Sleep Breath 2020 Jan 2. Epub 2020 Jan 2.

Sleep & Human Health Institute, 6739 Academy N.E., Suite 380, Albuquerque, NM, 87109, USA.

Study Objectives: Positive airway pressure (PAP) noncompliance remains a major barrier in obstructive sleep apnea (OSA) treatment. The PAP-NAP, a daytime PAP "test-drive," has been associated with increased PAP use, but risk factors and indications for the procedure remain unspecified.

Methods: A retrospective chart review was conducted on 139 patients who (1) were diagnosed with OSA (n = 116) or upper airway resistance syndrome (UARS) (n = 23); (2) adamantly refused to proceed with either a full-night attended titration or in-home trial of PAP; and (3) elected to proceed with a PAP-NAP instead. Read More

Sleep Sci 2019 Apr-Jun;12(2):72-78

University Institute for Regenerative Medicine and Oral Implantology - UIRMI (UPV/EHU-Fundación Eduardo Anitua), Sleep - Vitoria - Álava - Spain.

Study Objectives: Night-to-night variability in the apnea-hypopnea index (AHI) may affect the accuracy of the diagnosis of obstructive sleep apnea (OSA) and treatment selection. This study was conducted to assess the utility of the standard error of measurement (SEM) in predicting the night-to-night variability in the OSA.

Methods: Ninety nine patients underwent a 3-consecutive nights of sleep monitoring with a validated home portable monitoring devise (BTI-APNiA, BTI Biotechnology Institute, Vitoria, Spain). Read More

Sleep Sci 2019 Apr-Jun;12(2):65-71

University of Sao Paulo, Center of Clinical and Epidemiologic Research (CPCE) - São Paulo - São Paulo - Brazil.

Objective: Polygraphy (PG) is an attractive alternative for diagnosing obstructive sleep apnea (OSA) in patients with high pre-test probability. However, several patients may not present typical symptoms. In this scenario, it is unclear the performance of PG for diagnosing OSA in non-referred populations to sleep laboratories. Read More

J Otolaryngol Head Neck Surg 2019 Dec 3;48(1):69. Epub 2019 Dec 3.

Sections of Otolaryngology - Head and Neck Surgery and Pediatric Surgery, Department of Surgery, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

Background: Obstructive sleep apnea (OSA) is the most common indication for adenotonsillectomy in children. Home-based sleep oximetry continues to be used in the diagnosis of pediatric OSA despite a lack of correlation with lab-based polysomnography. This study investigates whether factors influence surgeons in selecting patients for home-based sleep oximetry, how the study findings are used in patient management, and whether abnormal oximetry findings are associated with post-operative complications. Read More

Ann Intern Med 2019 12;171(11):ITC81-ITC96

University of Pittsburgh, Pittsburgh, Pennsylvania (S.R.P.).

Obstructive sleep apnea (OSA) is very common but is frequently undiagnosed. Symptoms include loud snoring, nocturnal awakening, and daytime sleepiness. Motor vehicle accidents due to drowsy driving are a particular concern. Read More