29,821 results match your criteria Obstructive Sleep Apnea


Prevalence and Factors Contributing to Daytime and Nocturnal Hypoxemia in Chronic Heart Failure Patients.

Respiration 2019 Jan 17:1-10. Epub 2019 Jan 17.

Laboratoire HP2, INSERM U 1042, Grenoble Alpes University, Grenoble, France.

Background: Despite clinical optimization, many chronic heart failure (CHF) patients remain symptomatic with dyspnea and poor quality of life.

Study Objective: While oxygen therapy is prescribed in severe cases, the actual prevalence of different patterns of hypoxemia is unknown.

Methods: We analyzed 183 stable CHF patients with optimized medical treatment in the "MARS" database. Read More

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http://dx.doi.org/10.1159/000490734DOI Listing
January 2019

Adhesion molecule gene variants and plasma protein levels in patients with suspected obstructive sleep apnea.

PLoS One 2019 17;14(1):e0210732. Epub 2019 Jan 17.

UBC Hospital Sleep Disorders Program, Division of Respiratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

Study Objectives: Untreated obstructive sleep apnea (OSA) patients have an increased risk of cardiovascular disease (CVD). Adhesion molecules, including soluble E-selectin (sE-selectin), intercellular adhesion molecule-1 (ICAM-1), and vascular adhesion molecule-1 (VCAM-1), are associated with incident CVD. We hypothesized that specific genetic variants will be associated with plasma levels of adhesion molecules in suspected OSA patients. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210732PLOS
January 2019

Normal-tension glaucoma: managing a case of mistaken identity.

Authors:
Dan Samaha

Clin Exp Optom 2019 Jan 16. Epub 2019 Jan 16.

School of Optometry, University of Montreal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1111/cxo.12870DOI Listing
January 2019

Palatine Tonsil Stenting of the Airway as Determined by Drug-Induced Sleep Endoscopy.

Case Rep Otolaryngol 2018 10;2018:2614143. Epub 2018 Dec 10.

Department of Otolaryngology-Head and Neck Surgery, West Virginia University School of Medicine, Morgantown, WV, USA.

Objective: To demonstrate lateral pharyngeal wall collapse and increased apnea-hypopnea index in a child posttonsillectomy.

Background: Some children have worsening of their sleep symptoms after tonsillectomy for obstructive sleep apnea. This case report demonstrates an open airway on drug-induced sleep endoscopy (DISE) in a child with tonsillar hypertrophy followed by more pronounced airway obstruction related to lateral pharyngeal wall collapse after tonsillectomy. Read More

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http://dx.doi.org/10.1155/2018/2614143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311753PMC
December 2018
1 Read

The HMGB1-RAGE/TLR-TNF-α signaling pathway may contribute to kidney injury induced by hypoxia.

Exp Ther Med 2019 Jan 6;17(1):17-26. Epub 2018 Nov 6.

Department of Respiratory and Critical Medicine, Peking University First Hospital, Beijing 100034, P.R. China.

The hypoxia-reoxygenation process of obstructive sleep apnea (OSA) may cause oxidative stress injury of the kidney, but the molecular mechanisms are not clear. The present study aimed to investigate whether high mobility group box 1 protein (HMGB1) and its subsequent inflammatory pathway served a role in kidney injury. Adult Sprague Dawley rats were used to establish hypoxia models: Continuous hypoxia, intermittent hypoxia and intermittent hypoxia with hypercapnia. Read More

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http://dx.doi.org/10.3892/etm.2018.6932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307518PMC
January 2019

Molecular Pathways and Respiratory Involvement in Lysosomal Storage Diseases.

Int J Mol Sci 2019 Jan 15;20(2). Epub 2019 Jan 15.

Rare Metabolic Diseases Unit, Pediatric Department, Fondazione MBBM, Università degli Studi di Milano Bicocca, San Gerardo Hospital, ASST di Monza, 20900 Monza, Italy.

Lysosomal storage diseases (LSD) include a wide range of different disorders with variable degrees of respiratory system involvement. The purpose of this narrative review is to treat the different types of respiratory manifestations in LSD, with particular attention being paid to the main molecular pathways known so far to be involved in the pathogenesis of the disease. A literature search was conducted using the Medline/PubMed and EMBASE databases to identify studies, from 1968 through to November 2018, that investigated the respiratory manifestations and molecular pathways affected in LSD. Read More

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http://dx.doi.org/10.3390/ijms20020327DOI Listing
January 2019

Apnea hypopnea index during rapid eye movement sleep with diabetic retinopathy in patients with type 2 diabetes.

J Clin Endocrinol Metab 2019 Jan 11. Epub 2019 Jan 11.

Department of Endocrinology and Metabolism, Toranomon Hospital, Tokyo, Japan.

Context: Recent studies based on home sleep apnea testing (HSAT) reported the potential association of sleep disordered breathing (SDB), such as obstructive sleep apnea (OSA), with diabetic retinopathy (DR). A few studies showed that the apnea hypopnea index during rapid eye movement sleep (REM-AHI) is associated with glycated hemoglobin and hypertension, two known risk factors for DR. However, there are no studies that have evaluated the association of REM-AHI with DR because previous studies were based on HSAT. Read More

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http://dx.doi.org/10.1210/jc.2018-00946DOI Listing
January 2019

Renal Cortical Oxygen Tension is Decreased Following Exposure to Long-term but not Short-term Intermittent Hypoxia in the Rat.

Am J Physiol Renal Physiol 2019 Jan 16. Epub 2019 Jan 16.

Physiology, University College Cork, Ireland.

Chronic kidney disease (CKD) occurs in more than 50% of patients with obstructive sleep apnea (OSA). However, the impact of intermittent hypoxia (IH) on renal function and oxygen homeostasis is unclear. Male Sprague Dawley rats were exposed to IH (270 secs at 21% O; 90 secs hypoxia, 6. Read More

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http://dx.doi.org/10.1152/ajprenal.00254.2018DOI Listing
January 2019

Obstructive Sleep Apnea and Cognitive Decline in Older Adults.

Authors:
Tomoyuki Kawada

Am J Respir Crit Care Med 2019 Jan 16. Epub 2019 Jan 16.

Nippon Medical School, Hygiene and Public Health, Bunkyo-Ku, Tokyo, Japan ;

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http://dx.doi.org/10.1164/rccm.201811-2173LEDOI Listing
January 2019

Reply to: Obstructive Sleep Apnea and Cognitive Decline in Older Adults.

Am J Respir Crit Care Med 2019 Jan 16. Epub 2019 Jan 16.

Hopital du Sacre-Coeur de Montreal, 67120, Center for Advanced Research in Sleep Medicine, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1164/rccm.201812-2280LEDOI Listing
January 2019

Atrial Fibrillation: A Review of Modifiable Risk Factors and Preventive Strategies.

Rom J Intern Med 2018 Dec 1. Epub 2018 Dec 1.

Department of Electrophysiology, Heart Center at University of Leipzig, Leipzig, Germany.

Atrial fibrillation (AF), as the most common cardiac arrhythmia worldwide, is associated with increased mortality and morbidity. Successful therapeutic strategies have been introduced so far, but they are associated with significant costs. Therefore, identification of modifiable risk factors of AF and the development of appropriate preventive strategies may play a substantial role in promoting community health and reducing health care system costs. Read More

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http://dx.doi.org/10.2478/rjim-2018-0045DOI Listing
December 2018

A giant parapharyngeal lipoma causing obstructive sleep apnea.

J Stomatol Oral Maxillofac Surg 2019 Jan 12. Epub 2019 Jan 12.

Department of Maxillo-Facial Surgery and stomatology, Nantes university Hospital, France.

Lipoma is the most common soft tissue mesenchymal neoplasm. Its occurrence is low in the oral cavity (1 to 4%) and in head and neck region (20 to 25 %). Usually asymptomatic and slowly growing, lipoma can compress neighboring cervico-facial structures causing dysphagia, dyspnea, or obstructive sleep apnea. Read More

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http://dx.doi.org/10.1016/j.jormas.2018.12.015DOI Listing
January 2019

Characteristics of obstructive sleep apnea in myasthenia gravis patients: a single center study.

Neurol Sci 2019 Jan 16. Epub 2019 Jan 16.

Department of Neurology, Kyungpook National University Chilgok Hospital, Daegu, South Korea.

Background: Recent studies have shown a high prevalence of obstructive sleep apnea in myasthenia gravis compared to the normal population. The aim of this study was to elucidate clinical and polysomnographic differences between clinically stable Korean MG patients with and without OSA.

Methods: A total of 18 consecutively stable MG patients were included in this prospective study. Read More

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http://dx.doi.org/10.1007/s10072-019-3706-1DOI Listing
January 2019

Case Report: Post obstructive pulmonary edema (POPE) Type II following elective adenotonsillectomy requiring novel use of high frequency oscillatory ventilation (HFOV).

F1000Res 2018 31;7:1373. Epub 2018 Aug 31.

Department of Pediatric Anesthesia, Alberta Children's Hospital, Calgary, Alberta, T3B 6A8, Canada.

This case report describes a previously healthy 14 year-old patient undergoing elective outpatient adenotonsillectomy that was complicated by acute postoperative pulmonary edema requiring 12 hours of high frequency oscillatory ventilation (HFOV) support.  We describe the clinical findings that led us to this rare diagnosis and management of post obstructive pulmonary edema (POPE) Type II, a rare but recognized complication following the surgical relief of an upper airway obstruction. This case is unique in that no previously published case report or review of POPE Type II has described the need for HFOV support. Read More

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http://dx.doi.org/10.12688/f1000research.16044.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325615PMC

Obesity cardiomyopathy: the role of obstructive sleep apnea and obesity hypoventilation syndrome.

Ir J Med Sci 2019 Jan 15. Epub 2019 Jan 15.

Respiratory Division, University Hospital Limerick, Limerick, Ireland.

The negative long-term health consequences of obesity are well known to both the medical profession and general public. Despite this, the number of obese and overweight individuals worldwide continues to steadily rise. Although obesity has long been associated with an increased risk for cardiovascular disease and mortality, the classification of a cardiomyopathy of obesity is a more recent development. Read More

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http://link.springer.com/10.1007/s11845-018-01959-5
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http://dx.doi.org/10.1007/s11845-018-01959-5DOI Listing
January 2019
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Torus mandibularis affects the severity and position-dependent sleep apnea in non-obese patients.

Clin Otolaryngol 2019 Jan 15. Epub 2019 Jan 15.

Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Korea.

Objective: Various anatomical structures of upper airway and physical differences are known to be risk factors for obstructive sleep apnea (OSA). Torus mandibularis is a structure that can appear on the inside of the mandible. Therefore, it is possible for tori to influence airway volume by occupying the space for tongue, and cause sleep apnea. Read More

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http://doi.wiley.com/10.1111/coa.13286
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http://dx.doi.org/10.1111/coa.13286DOI Listing
January 2019
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Revisiting age-related admission following tonsillectomy in the pediatric population.

Laryngoscope 2019 Jan 15. Epub 2019 Jan 15.

Pediatric Ear, Nose, and Throat Associates of Alabama, Children's Hospital of Alabama, Birmingham, Alabama, U.S.A.

Objectives/hypothesis: The objectives of this study were to examine patient outcomes using a 36-month age cutoff as a strict admission criterion following tonsillectomy, and review the safety and determine the plausibility of same-day discharge of children under 3 years old following tonsillectomy.

Study Design: Retrospective chart review.

Methods: A chart review of patients aged 24 to 42 months undergoing tonsillectomy over a 3-year period was conducted. Read More

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http://doi.wiley.com/10.1002/lary.27795
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http://dx.doi.org/10.1002/lary.27795DOI Listing
January 2019
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Maxillary protraction to treat pediatric obstructive sleep apnea and maxillary retrusion: a preliminary report.

Sleep Med 2018 Dec 26. Epub 2018 Dec 26.

Division of Sleep Medicine, Stanford University School of Medicine, Palo Alto, CA, USA.

Introduction: Midface retrusion creates a size deficiency problem in the upper airway that has been improved in children using surgical midface advancement and orthopedic protraction of the maxilla. The results of these treatments have been mostly promising at enlarging the pharyngeal airway. Recently introduced bone anchored maxillary protraction (BAMP) uses implant inserted devices in the jaws to pull the maxilla forward against a backward pressure to the lower jaw. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13899457183041
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http://dx.doi.org/10.1016/j.sleep.2018.12.005DOI Listing
December 2018
1 Read

Non-invasive ventilation in acute respiratory failure of patients with obesity hypoventilation syndrome.

Minerva Med 2018 Dec;109(6 Suppl 1):1-5

Unit of Respiratory Diseases and Allergies, Department of Internal Medicine (DiMI), San Martino University Hospital, Genoa, Italy.

Introduction: Non-invasive ventilation (NIV) has been used successfully for the management of acute respiratory failure (ARF) more often in the last two decades compared to prior decades. There are particular groups of patients that are more likely to benefit from NIV. One of these groups is patients with obesity hypoventilation syndrome (OHS). Read More

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http://dx.doi.org/10.23736/S0026-4806.18.05921-9DOI Listing
December 2018

Adulthood and childhood ADHD in patients consulting for obesity is associated with food addiction and binge eating, but not sleep apnea syndrome.

Appetite 2019 Jan 11. Epub 2019 Jan 11.

CHRU de Tours, Équipe de Liaison et de Soins en Addictologie & Clinique Psychiatrique Universitaire, 2 boulevard Tonnellé, 37044, Tours Cedex 9, France; Université de Tours, UMR INSERM U1253 iBrain « Brain and Imaging », 2 boulevard Tonnellé, 37044, Tours Cedex, France. Electronic address:

Introduction: The exact mechanisms underlying the established association between ADHD and obesity remain unclear. Food addiction and binge eating may contribute to this link. We examined for the first time the association between childhood/adult ADHD and food addiction/binge eating in patients with obesity, as well as the association between ADHD and sleep apnea syndrome. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01956663183130
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http://dx.doi.org/10.1016/j.appet.2019.01.013DOI Listing
January 2019
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Obstructive sleep apnea in patients with idiopathic normal-pressure hydrocephalus.

Authors:
Tomoyuki Kawada

J Neurol Sci 2019 Jan 9;397:155. Epub 2019 Jan 9.

Department of Hygiene and Public Health, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-Ku, Tokyo 113-8602, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0022510X193000
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http://dx.doi.org/10.1016/j.jns.2019.01.006DOI Listing
January 2019
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Depression is differently associated with sleep measurement in obstructive sleep apnea, restless leg syndrome and periodic limb movement disorder.

Psychiatry Res 2018 Dec 31;273:37-41. Epub 2018 Dec 31.

Department of Psychiatry, Changhua Christian Hospital, No.135, Nanxiao St., Changhua County 500 Changhua, Taiwan; Chung Shan Medical University, Taichung, Taiwan. Electronic address:

Depression causes sleep disturbance and is associated with various sleep-related disorders. However, how depression affects the symptomatic presentation of different sleep-related disorders is unclear. In this study, we investigated the sleep parameters of different sleep-related disorders between depressive and non-depressive patients. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01651781183151
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http://dx.doi.org/10.1016/j.psychres.2018.12.166DOI Listing
December 2018
1 Read

Is Maxillomandibular Advancement Associated With Comorbidity Reduction in Patients With Obstructive Sleep Apnea?

J Oral Maxillofac Surg 2018 Dec 17. Epub 2018 Dec 17.

Associate Professor, Department of Oral and Maxillofacial Surgery, Massachusetts General Hospital, Boston, MA. Electronic address:

Purpose: This study investigated whether patients with documented obstructive sleep apnea (OSA) who have a decrease in apnea-hypopnea index (AHI) score and self-reported symptoms after maxillomandibular advancement (MMA) with genial tubercle advancement (GTA) also have a change in their medical comorbidity profile a minimum of 2 years postoperatively. Changes in the quantity of medical diagnoses, quantity of prescription medications, and average weight and body mass index (BMI) were assessed.

Patients And Methods: This is a retrospective cohort study of patients with a diagnosis of OSA (AHI score >5 on polysomnogram [PSG]) treated at the Massachusetts General Hospital (Boston, MA) with MMA and GTA from 2001 through 2015. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02782391183137
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http://dx.doi.org/10.1016/j.joms.2018.12.006DOI Listing
December 2018
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Treatment of Sleep Apnea in Patients with Paroxysmal Atrial Fibrillation: Design and Rationale of a Randomized Controlled Trial.

Scand Cardiovasc J 2019 Jan 14:1-20. Epub 2019 Jan 14.

a Department of Cardiology , Oslo University Hospital , Rikshospitalet , Oslo , Norway.

Rationale: Atrial fibrillation is associated with increased mortality as well as morbidity. There is strong evidence for an association between atrial fibrillation and sleep apnea. It is not known whether treatment of sleep apnea with continuous positive airway pressure (CPAP) will reduce the burden of atrial fibrillation. Read More

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https://www.tandfonline.com/doi/full/10.1080/14017431.2019.1
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http://dx.doi.org/10.1080/14017431.2019.1567933DOI Listing
January 2019
1 Read

Inducers of post-apneic blood pressure fluctuation monitored by pulse transfer time measurement in obstructive sleep apnea varied with syndrome severity.

Sleep Breath 2019 Jan 12. Epub 2019 Jan 12.

Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, China.

Purpose: This study investigated the properties of blood pressure (BP) fluctuation and sympathovagal imbalance with the severity of OSAS.

Methods: Nocturnal BP was continuously monitored by polysomnography for mild (n = 33), moderate (n = 34), and severe (n = 37) OSAS patients. Apnea-related systolic BP elevation (△SBP) indicated the amplitude of BP fluctuation. Read More

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http://dx.doi.org/10.1007/s11325-018-1770-zDOI Listing
January 2019

Episodic Migraine Comorbidities: Avoiding Pitfalls and Taking Therapeutic Opportunities.

Curr Pain Headache Rep 2019 Jan 12;23(1). Epub 2019 Jan 12.

Mount Sinai Beth Israel, New York, NY, USA.

Migraine is a common neurologic disorder. This article will discuss a few factors that influence migraine (mostly episodic) and its treatment, such as sleep, obstructive sleep apnea (OSA), obesity, and affective disorders, as well as autoimmune diseases. Practitioners must be aware of these coexisting conditions (comorbidities) as they affect treatment. Read More

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http://link.springer.com/10.1007/s11916-019-0742-8
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http://dx.doi.org/10.1007/s11916-019-0742-8DOI Listing
January 2019
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Correlations between Waist and Neck Circumferences and Obstructive Sleep Apnea Characteristics.

Sleep Vigil 2018 Dec 15;2(2):111-118. Epub 2018 May 15.

Department of Anesthesiology, University of California at Los Angeles, Los Angeles, CA 90095, USA.

Purpose: The body mass index (BMI), an estimate of body fat, provides a rather imprecise indication of risk for obstructive sleep apnea (OSA). We examined whether other measures, including waist and neck circumference, provide improved indicators of risk in treatment-naïve OSA subjects.

Methods: We studied 59 OSA subjects [age, 48. Read More

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http://dx.doi.org/10.1007/s41782-018-0041-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326580PMC
December 2018
1 Read

Association of Obstructive Sleep Apnea With Cardiovascular Outcomes in Patients With Acute Coronary Syndrome.

J Am Heart Assoc 2019 Jan;8(2):e010826

4 Department of Otolaryngology Head & Neck Surgery Beijing Anzhen Hospital Capital Medical University Beijing China.

Background The prognostic significance of obstructive sleep apnea ( OSA ) in patients with acute coronary syndrome ( ACS ) in the contemporary era is unclear. We performed a large, prospective cohort study and did a landmark analysis to delineate the association of OSA with subsequent cardiovascular events after ACS onset. Methods and Results Between June 2015 and May 2017, consecutive eligible patients admitted for ACS underwent cardiorespiratory polygraphy during hospitalization. Read More

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http://dx.doi.org/10.1161/JAHA.118.010826DOI Listing
January 2019
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Perioperative impact of sleep apnea in a high-volume specialty practice with a strong focus on regional anesthesia: a database analysis.

Reg Anesth Pain Med 2019 Jan 11. Epub 2019 Jan 11.

Department of Anesthesiology, Critical Care and Pain Management, Hospital for Special Surgery, New York, USA

Background And Objectives: Obstructive sleep apnea (OSA) is a risk factor for adverse postoperative outcome and perioperative professional societies recommend the use of regional anesthesia to minimize perioperative detriment. We studied the impact of OSA on postoperative complications in a high-volume orthopedic surgery practice, with a strong focus on regional anesthesia.

Methods: After Institutional Review Board approval, 41 766 cases of primary total hip and knee arthroplasties (THAs/TKAs) from 2005 to 2014 were extracted from institutional data of the Hospital for Special Surgery (approximately 5000 THAs and 5000 TKAs annually, of which around 90% under neuraxial anesthesia). Read More

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http://dx.doi.org/10.1136/rapm-2018-000038DOI Listing
January 2019

Asthma is associated with increased probability of needing CPAP in children with severe obstructive sleep apnea.

Pediatr Pulmonol 2019 Jan 10. Epub 2019 Jan 10.

Division of Pulmonary and Sleep Medicine, Children's National Health System, Washington, District of Columbia.

Objective: Initiation of continuous positive airway pressure (CPAP) in children with severe obstructive sleep apnea syndrome (OSAS) is challenging and the distinct features of the subset of children requiring CPAP are poorly defined. Asthma often coexists with OSAS in children. The goal of this study was to explore the influence of asthma in the need for CPAP therapy in children with severe OSAS. Read More

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http://doi.wiley.com/10.1002/ppul.24245
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http://dx.doi.org/10.1002/ppul.24245DOI Listing
January 2019
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Influence of Preoperative Weight Loss on Outcomes of Bariatric Surgery for Patients Under the Enhanced Recovery After Surgery Protocol.

Obes Surg 2019 Jan 10. Epub 2019 Jan 10.

2nd Department of General Surgery, Jagiellonian University Medical College, ul. Kopernika 21, 30-501, Krakow, Poland.

Introduction: The enhanced recovery after surgery (ERAS) protocol, which emphasizes preoperative interventions, is safely implemented in patients undergoing bariatric surgery. Patients are additionally encouraged to achieve weight loss preoperatively. We aimed to identify factors contributing to preoperative weight loss and assess their influence on outcomes of bariatric surgery among patients under the ERAS protocol. Read More

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http://link.springer.com/10.1007/s11695-018-03660-z
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http://dx.doi.org/10.1007/s11695-018-03660-zDOI Listing
January 2019
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Editorial: Obstructive Sleep Apnea and the Brain.

Front Surg 2018 21;5:78. Epub 2018 Dec 21.

Neuroscience Research Australia (NeuRA) and the University of New South Wales, Sydney, NSW, Australia.

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https://www.frontiersin.org/article/10.3389/fsurg.2018.00078
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http://dx.doi.org/10.3389/fsurg.2018.00078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6315176PMC
December 2018
1 Read

Prevalence of obstructive sleep apnea in primary care patients with hypertension.

J Gen Fam Med 2019 Jan 24;20(1):39-42. Epub 2018 Oct 24.

Muribushi Project for Okinawa Residency Programs Okinawa Japan.

Background: As the number of patients with hypertension who have obstructive sleep apnea (OSA) might be underestimated, this study aimed to explore the prevalence of OSA and develop a diagnostic algorithm for moderate or severe OSA among primary care (PC) patients with hypertension.

Methods: This multicenter cross-sectional study enrolled patients diagnosed with hypertension aged 18 years or older in Japan from October 2012 to September 2014.

Results: Forty-nine patients (64. Read More

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http://doi.wiley.com/10.1002/jgf2.214
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http://dx.doi.org/10.1002/jgf2.214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321825PMC
January 2019
1 Read

Is only fixed positive airway pressure a robust tool for kidney protection in patients with obstructive sleep apnea?

J Thorac Dis 2018 Nov;10(Suppl 33):S3819-S3823

Division of nephrology, Department of Internal Medicine; NHIS Ilsan Hospital, Goyang, Korea.

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http://dx.doi.org/10.21037/jtd.2018.10.91DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297492PMC
November 2018

Sleep-related painful erection in a patient with obstructive sleep apnea syndrome.

Int J Impot Res 2019 Jan 10. Epub 2019 Jan 10.

Department of Urology, Peking Union Medical College Hospital, Beijing, China.

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http://www.nature.com/articles/s41443-018-0110-y
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http://dx.doi.org/10.1038/s41443-018-0110-yDOI Listing
January 2019
1 Read

Skeletal changes after rapid maxillary expansion in children with obstructive sleep apnea evaluated by low-dose multi-slice computed tomography.

Sleep Med 2018 Dec 16. Epub 2018 Dec 16.

Stanford University Sleep Medicine Division, Redwood City, CA, USA.

Objective: The objective of this study was to evaluate the skeletal effects of rapid maxillary expansion (RME) therapy performed using teeth as anchors, in obstructive sleep apnea (OSA) children, by low-dose computed tomography (CT) of the midpalatal suture opening, maxillary base width, nasal cavities width, first molar angulation and, unlike most studies in the literature, on the pterygoid processes distance.

Methods: Fourteen children (mean age 8.68 years) with OSA presenting a malocclusion characterized by upper-jaw contraction had 16-Multislice CT (MSCT) scans taken before (T0) and after (T1) RME. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S13899457183027
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http://dx.doi.org/10.1016/j.sleep.2018.11.023DOI Listing
December 2018
1 Read

Successful screening of sleep-disordered breathing using a pacemaker-based algorithm in Japan.

J Cardiol 2019 Jan 7. Epub 2019 Jan 7.

Yokohama City University Graduate School of Medicine, Department of Medical Science and Cardio-renal Medicine, Yokohama, Japan.

Background: Recent pacemakers with transthoracic impedance sensors have a specific algorithm identifying sleep apnea (SA). Our aim was to evaluate the algorithm in Japanese patients.

Methods: Consecutive patients implanted with a pacemaker with sleep apnea monitoring algorithm at our hospital were enrolled prospectively. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09145087183034
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http://dx.doi.org/10.1016/j.jjcc.2018.10.007DOI Listing
January 2019
2 Reads

Treating moderate-severe obstructive sleep apnoea for cardiovascular health: Is what stake the stakeholder holds important?

Respirology 2019 Jan 10. Epub 2019 Jan 10.

CIRUS, Sleep and Circadian Group, Woolcock Institute, University of Sydney, Sydney, NSW, Australia.

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http://doi.wiley.com/10.1111/resp.13467
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http://dx.doi.org/10.1111/resp.13467DOI Listing
January 2019
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Imbalance of osteoprotegerin/receptor activator of nuclear factor-κB ligand and oxidative stress in patients with obstructive sleep apnea-hypopnea syndrome.

Chin Med J (Engl) 2019 Jan;132(1):25-29

Department of Respiratory Medicine, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.

Background: Obstructive sleep apnea-hypopnea syndrome (OSAHS) is associated with a higher prevalence of osteoporosis. However, the underlying mechanisms linking OSAHS with bone loss are still unclear. The aim of this study was to investigate the changes of receptor activator of nuclear factor-κB ligand (RANKL, an osteoclastogenesis-promoting factor) and osteoprotegerin (OPG, the decoy receptor for RANKL), oxidative stress and bone metabolism markers in OSAHS, in order to understand the potential mechanisms underlying bone loss in OSAHS patients. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000046DOI Listing
January 2019
2 Reads

Immediate Use of Continuous Positive Airway Pressure in Patients With Obstructive Sleep Apnea Following Transsphenoidal Pituitary Surgery: A Case Series.

J Neurosurg Anesthesiol 2019 Jan 8. Epub 2019 Jan 8.

Department of Anesthesiology and Perioperative Care, Vancouver General Hospital.

Background: Patients who undergo transsphenoidal pituitary resection have an elevated risk of obstructive sleep apnea (OSA) yet their outcomes and the safety of continuous positive airway pressure (CPAP) remains unclear. Our study objective was to determine the incidence of complications related to the use of early positive airway pressure following pituitary resection.

Methods: We retrospectively identified all patients who underwent endoscopic transsphenoidal pituitary tumor resection between January 1, 2005 and March 24, 2016 at our institution, including those with diagnosed or suspected OSA. Read More

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http://dx.doi.org/10.1097/ANA.0000000000000573DOI Listing
January 2019
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Determinants of depressive mood in coronary artery disease patients with obstructive sleep apnea and response to continuous positive airway pressure treatment in non-sleepy and sleepy phenotypes in the RICCADSA cohort.

J Sleep Res 2019 Jan 9:e12818. Epub 2019 Jan 9.

Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

We explored determinants of depressive mood in adults with coronary artery disease and obstructive sleep apnea and response to positive airway pressure treatment in sleepy and non-sleepy phenotypes. In this secondary analysis of the RICCADSA trial conducted in Sweden, 493 cardiac patients with obstructive sleep apnea (n = 386) or no obstructive sleep apnea (n = 107) with complete Epworth Sleepiness Scale and Zung Self-rating Depression Scale questionnaires were included. Sleepy (Epworth Sleepiness Scale ≥10) versus non-sleepy (Epworth Sleepiness Scale <10) patients with depressive mood (Zung Self-rating Depression Scale score ≥50) were evaluated after 3 and 12 months of positive airway pressure treatment. Read More

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http://doi.wiley.com/10.1111/jsr.12818
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http://dx.doi.org/10.1111/jsr.12818DOI Listing
January 2019
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Tempol relieves lung injury in a rat model of chronic intermittent hypoxia via suppression of inflammation and oxidative stress.

Iran J Basic Med Sci 2018 Dec;21(12):1238-1244

Department of Respiratory Medicine, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan 650101, People's Republic of China.

Objectives: Obstructive sleep apnea (OSA) is confirmed to cause lesions in multiple organs, especially in the lung tissue. Tempol is an antioxidant that has been reported to restrain inflammation and oxidative stress, with its role in OSA-induced lung injury being unclear. This study aimed to investigate the beneficial effect of tempol on chronic intermittent hypoxia (IH)-induced lung injury. Read More

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http://dx.doi.org/10.22038/ijbms.2018.31716.7714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312670PMC
December 2018

Obstructive Sleep Apnea Screening in Patients With Atrial Fibrillation: Missed Opportunities for Early Diagnosis.

J Clin Med Res 2019 Jan 3;11(1):21-25. Epub 2018 Dec 3.

Department of Internal Medicine, Staten Island University Hospital Staten Island, 475 Seaview Ave, Staten Island, NY 10305, USA.

Background: "There is a high prevalence of obstructive sleep apnea (OSA) among patients with atrial fibrillation (AF). There is also strong evidence that proper OSA management can reduce AF recurrence." Polysomnography is the gold standard for OSA diagnosis, but screening tests, such as STOP-BANG, have been successful in identifying patients at risk for OSA. Read More

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http://dx.doi.org/10.14740/jocmr3635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306129PMC
January 2019

Drug Induced Sleep Endoscopy in Obstructive Sleep Apnea.

Tanaffos 2018 Feb;17(2):122-126

Department of Pulmonary and Critical Care Medicine, Lung Diseases Research Center, Faculty of Medicine, Mashhad University of Medical Science, Mashhad, Iran.

Background: One of the main challenges of surgical treatment in Obstructive Sleep Apnea (OSA) is identifying the correct site of upper airway obstruction in an individual patient. Drug-Induced Sleep Endoscopy (DISE) in sedated patients with obstructive sleep apnea is the technique of choice for revealing anatomic and dynamic collapsible areas.

Materials And Methods: In a prospective cross-sectional study adult patients with OSA documented by polysomnography were evaluated by sleep endoscopy. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320559PMC
February 2018
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Single versus double suspension sutures for selected cases of obstructive sleep apnea.

Auris Nasus Larynx 2019 Jan 6. Epub 2019 Jan 6.

Faculty of Medicine, Zagazig University, Egypt.

Objective: To compare the results of expansion pharyngoplasty using bilateral single palatal suspension sutures (SSS) versus double suspension sutures (DSS) for the treatment of selected cases of obstructive sleep apnea (OSA) with retropalatal collapse.

Methods: Patients were randomly categorized into two groups: the first group for whom bilateral SSS were performed and a second group for whom bilateral DSS were done. Snoring on the basis of the visual analog scale (VAS), Epworth Sleepiness Scale (ESS), apnea hypopnea index (AHI), lowest O saturation were assessed preoperatively and 6 months postoperatively in all patients. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03858146183072
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http://dx.doi.org/10.1016/j.anl.2018.12.014DOI Listing
January 2019
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The validity of two commercially-available sleep trackers and actigraphy for assessment of sleep parameters in obstructive sleep apnea patients.

PLoS One 2019 9;14(1):e0210569. Epub 2019 Jan 9.

Chest Service, Saint-Pierre University Hospital, Brussels, Belgium and Université Libre de Bruxelles, Brussels, Belgium.

Objective: The use of activity and sleep trackers that operate through dedicated smartphone applications has become popular in the general population. However, the validity of the data they provide has been disappointing and only Total Sleep Time (TST) is reliably recorded in healthy individuals for any of the devices tested. The purpose of this study was to evaluate the ability of two sleep trackers (Withings pulse 02 (W) and Jawbone Up (U)) to measure sleep parameters in patients suffering from obstructive sleep apnea (OSA). Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210569PLOS
January 2019
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Differences in three-dimensional craniofacial anatomy between responders and non-responders to mandibular advancement splint treatment in obstructive sleep apnoea patients.

Eur J Orthod 2019 Jan 5. Epub 2019 Jan 5.

Discipline of Orthodontics, Faculty of Dentistry, University of Sydney, Sydney Dental Hospital, Sydney Local Health District, New South Wales, Australia.

Aim: The primary aim of this study was to assess the differences in the upper airway morphology between responders and non-responders to mandibular advancement splint (MAS) treatment in obstructive sleep apnoea (OSA) management. The secondary aim was to assess the correlation between the minimum cross-sectional area of the upper airway and the anatomical structures (i.e. Read More

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https://academic.oup.com/ejo/advance-article/doi/10.1093/ejo
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http://dx.doi.org/10.1093/ejo/cjy085DOI Listing
January 2019
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SEVERE OSAS CAUSES SYSTEMIC MICROVASCULAR DYSFUNCTION. CLINICAL EVALUATION OF NINETY-EIGHT OSAS PATIENTS.

Clin Otolaryngol 2019 Jan 8. Epub 2019 Jan 8.

Bakırköy Dr.Sadi Konuk Training and Research Hospital, Department of Otorhinolaryngology - Head and Neck Surgery, Istanbul, Turkey.

Obstructive sleep apnea syndrome is described as "Sleep disorder characterized by recurrent episodes of upper respiratory tract obstruction (apnea) and decreased blood-oxygen saturation occurring during sleep". The assessment of systemic microvascular density and reactivity is important for cardiovascular disease pathophysiology and cardiovascular risk classification. Cutaneous microcirculation which can be demonstrated via nailfold capillaroscopy is an easily accessible and acceptable non-invasive method for the assessment of systemic microcirculation. Read More

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http://doi.wiley.com/10.1111/coa.13285
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http://dx.doi.org/10.1111/coa.13285DOI Listing
January 2019
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