205,874 results match your criteria Obstruction Large Bowel

Subacute duodenal obstruction caused by Common Celiaco-Mesenteric Trunk anomaly-A case report.

Int J Surg Case Rep 2021 May 26;83:106043. Epub 2021 May 26.

Department of General Surgery, Grant Government Medical College and Sir J&J Group of Hospitals, Mumbai, India.

Introduction And Importance: The origin of the mesenteric vasculature is highly variable. One such variation is the common celiaco-mesenteric trunk (CMT). To our knowledge, this is the first reported case of subacute duodenal obstruction caused by common CMT. Read More

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Tbx18-positive cells-derived myofibroblasts contribute to renal interstitial fibrosis via transforming growth factor-β signaling.

Exp Cell Res 2021 Jun 9:112682. Epub 2021 Jun 9.

Department of Cardiology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address:

It has been demonstrated that the T-box family transcription factor 18 (Tbx18) -positive cells give rise to renal mesenchymal cells and contribute to the development of the urinary system. However, it is unclear whether Tbx18-positive cells are the origin of the myofibroblasts during renal fibrosis. The present study aimed to determine the contribution of Tbx18-positive cells in kidney fibrosis and their underlying mechanism. Read More

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Initial experience of endoscopic ultrasound-guided antegrade covered stent placement with long duodenal extension for malignant distal biliary obstruction (with video).

J Hepatobiliary Pancreat Sci 2021 Jun 12. Epub 2021 Jun 12.

Division of Gastroenterology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea.

Background/purpose: This study aimed to evaluate the feasibility of endoscopic ultrasound (EUS)-guided antegrade covered stent placement with long duodenal extension (EASL) for malignant distal biliary obstruction (MDBO) with duodenal obstruction (DO) or surgically altered anatomy (SAA) after failed endoscopic retrograde cholangiopancreatography (ERCP).

Methods: Outcomes were technical and clinical success, reintervention rate, adverse events, stent patency, and overall survival. Inverse probability of treatment weighting (IPTW) and competing-risk analysis were performed to compare with conventional EUS-BD. Read More

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The role of neutrophils in asthma.

Zhejiang Da Xue Xue Bao Yi Xue Ban 2021 Feb;50(1):123-130

Department of Respiratory and Critical Care Medicine,the Second Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310009,China.

Bronchial asthma is a chronic respiratory disease,characterized by airway inflammation,airway hyperresponsiveness,reversible airway obstruction and airway remodeling,in which a variety of cells including airway inflammatory cells and structural cells are involved. Previous studies have shown that asthma is mainly driven by Th2 cytokines IL-4,IL-5,and IL-13,leading to airway eosinophil inflammation. With further research,however,it has been found that neutrophils are also closely related to asthma. Read More

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February 2021

Predictors of Respiratory Dysfunction at Diagnosis of Robin Sequence.

Laryngoscope 2021 Jun 12. Epub 2021 Jun 12.

Department of Plastic and Craniofacial Surgery, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.

Objectives/hypothesis: Robin sequence (RS) consists of associated micrognathia, glossoptosis, and respiratory dysfunction, with or without cleft palate. Studies on how different patient characteristics impact the severity of respiratory dysfunction are scarce and contradictory; this study investigates how different features affect respiratory obstruction severity at diagnosis of RS in controlled analysis.

Study Design: Retrospective cohort study that enrolled 71 RS patients under 90 days old who received care in our institution from 2009 to 2020. Read More

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A diagnostic delay of 10 years in the DanEoE cohort calls for focus on education - a population-based cross-sectional study of incidence, diagnostic process and complications of eosinophilic oesophagitis in the North Denmark Region.

United European Gastroenterol J 2021 Jun 12. Epub 2021 Jun 12.

Centre for Clinical Research, North Denmark Regional Hospital, Hjørring, Denmark.

Background: In the North Denmark Region with a population of 580,000 the awareness of eosinophilic oesophagitis (EoE) increased after 2011 due to a regional biopsy guideline. However, very little was known of the incidence, diagnostic process, or complications of EoE in Denmark.

Objective: The objectives of the study were to establish a cohort of EoE patients and describe the incidence, diagnostic process, and complications of EoE. Read More

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miR-126-3p is essential for CXCL12-induced angiogenesis.

J Cell Mol Med 2021 Jun 12. Epub 2021 Jun 12.

INSERM U1148, Laboratory for Vascular Translational Sciences (LVTS), UFR SMBH Université Sorbonne Paris Nord, Bobigny, France.

Atherosclerosis, in the ultimate stage of cardiovascular diseases, causes an obstruction of vessels leading to ischemia and finally to necrosis. To restore vascularization and tissue regeneration, stimulation of angiogenesis is necessary. Chemokines and microRNAs (miR) were studied as pro-angiogenic agents. Read More

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Augmented Package of Palliative Care for Women With Cervical Cancer: Responding to Refractory Suffering.

JCO Glob Oncol 2021 Jun;7:886-895

Department of Non-communicable Diseases, World Health Organization, Geneva, Switzerland.

The essential package of palliative care for cervical cancer (EPPCCC), described elsewhere, is designed to be safe and effective for preventing and relieving most suffering associated with cervical cancer and universally accessible. However, it appears that women with cervical cancer, more frequently than patients with other cancers, experience various types of suffering that are refractory to basic palliative care such as what can be provided with the EPPCCC. In particular, relief of refractory pain, vomiting because of bowel obstruction, bleeding, and psychosocial suffering may require additional expertise, medicines, or equipment. Read More

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Role of Imaging in Obstetric Interventions: Criteria, Considerations, and Complications.

Radiographics 2021 Jun 11:200163. Epub 2021 Jun 11.

From the Department of Radiology and Biomedical Imaging, University of California San Francisco, 505 Parnassus Ave, Box 0628, San Francisco, CA 94143-0628 (P.J., V.A.F.); Department of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Conn (M.V.R.); Department of Radiology, Winthrop University Hospital, Mineola, NY (D.S.K.); and Department of Radiology, University of Washington, Seattle, Wash (M.M.).

US has an established role in the prenatal detection of congenital and developmental disorders. Many pregnant women undergo US at 18-20 weeks of gestation for assessment of fetal anatomy and detection of structural anomalies. With advances in fetoscopy and minimally invasive procedures, in utero fetal interventions can be offered to address some of the detected structural and physiologic fetal abnormalities. Read More

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How I Handle Retreatment of LUTS Following a Failed MIST.

Curr Urol Rep 2021 Jun 11;22(8):40. Epub 2021 Jun 11.

Department of Urology, Weill Cornell Medical College of Cornell University, 425 East 61st street, 12th floor, New York, NY, 10065, USA.

Purpose Of Review: The goal of this paper is to review retreatment management after failed minimally invasive treatment (MIST) of various technologies.

Recent Findings: A failed MIST can be defined by the return, persistence, or worsening of LUTS, as documented by symptom scores. Persistence, development, or recurrence of comorbidities such as recurrent urinary tract infection (UTI), retention, stones, hematuria, and incontinence can also signal a failed MIST. Read More

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Clinical Application of PEEK as a Provisional Fixed Dental Prosthesis Retained by Reciprocated Guide Surfaces of Healing Abutments During Dental Implant Treatment.

Int J Oral Maxillofac Implants 2021 May-Jun;36(3):581-586

Purpose: The aim of this study was to evaluate the clinical use of a high-performance polymer, polyether ether ketone (PEEK), as a material for use in provisional fixed dental prostheses (FDPs) that can be retained by reciprocated guide surfaces of hexagonal-shaped healing abutments during dental implant treatment.

Materials And Methods: Patients requiring teeth replacement with dental implants for partially and fully edentulous cases in the maxilla and mandible were included. The provisional FDP was fabricated with hex castable copings and PEEK granules using the lost wax technique. Read More

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Effects of parenteral nutrition and hydration on survival in advanced cancer patients with malignant bowel obstruction: secondary analysis of a multicenter prospective cohort study.

Support Care Cancer 2021 Jun 10. Epub 2021 Jun 10.

Palliative and Supportive Care Division, Seirei Mikatahara General Hospital, 3453 Mikatahara-cho, Kita-ku, Hamamatsu City, Shizuoka, 433-8558, Japan.

Purpose: The benefits of parenteral nutrition and hydration (PNH) in patients with advanced cancer remain unknown. Therefore, we conducted a prospective multicenter cohort study to assess the effects of PNH on survival in patients with malignant bowel obstruction (MBO).

Methods: The present study was a secondary analysis. Read More

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Case Report: Complicated Meckel Diverticulum Spectrum in Children.

Front Surg 2021 25;8:674382. Epub 2021 May 25.

Pediatric Surgery Division, Department of Surgery, Faculty of Medicine, Public Health and Nursing, Universitas Gadjah Mada/Dr. Sardjito Hospital, Yogyakarta, Indonesia.

Meckel diverticulum (MD) is the most common congenital anomaly of the intestines, with an incidence of 2% of the general population. It can present as various clinical features with complications and be life threatening if diagnosis is delayed and treatment late. We report three pediatric cases with complicated MD: one female presented with small-bowel obstruction, one male with peritonitis, and one female with severe iron-deficiency anemia, without gross gastrointestinal bleeding nor any ectopic gastric mucosa. Read More

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The Detective Value of Magnetically Controlled Robotic Capsule Endoscopy in Patients With Suspected Small Intestinal Disease.

Front Med (Lausanne) 2021 25;8:610563. Epub 2021 May 25.

Department of Gastroenterology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.

To explore the detective value of magnetically controlled robotic capsule endoscopy (MCRCE) in patients with suspected small intestinal disease. In total, 1,802 patients with suspected small intestinal disease and negative gastroenteroscopy from Shanghai Jiao Tong University Affiliated Sixth People's Hospital were examined with MCRCE, and the data were collected for further analysis. Among the 1,802 patients who were examined with MCRCE, 974 were diagnosed with small intestinal disease, reaching a positive detection rate of 54. Read More

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"Poor Effort" Does Not Account for Reduced Forced Vital Capacity in Asthmatic Children.

Front Pediatr 2021 25;9:596384. Epub 2021 May 25.

Department of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, China.

Poor forced vital capacity (FVC) effort has been considered to be the main reason for FVC reduction by the ATS/ERS guideline; however, this has rarely been mentioned in previous studies. The present study aims to determine whether reduced FVC in asthmatic children is correlated to poor FVC effort. A total of 209 asthmatic children within 5-13 years old were included and divided into reduced FVC ("restricted," = 66) and typical obstruction group ("obstructed," = 143). Read More

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Cystic Prostatic Carcinoma - A Clinical Case and Literature Review.

Res Rep Urol 2021 3;13:335-340. Epub 2021 Jun 3.

Urology Department, St. Luke's Clinical Hospital, Saint-Petersburg, Russia.

Cystic formations in the prostate are quite common, but the vast majority are benign. The cystic form of prostate adenocarcinoma can present unexpected symptoms, and management can be difficult because of the local advanced stage of the disease. A unique feature of this case is the surgical local cancer treatment. Read More

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Endobronchial Tumor With Ball Valve Mechanism: A Real Airway Emergency.

Cureus 2021 Jun 8;13(6):e15522. Epub 2021 Jun 8.

Interventional Pulmonology, Norton Thoracic Institute, Phoenix , USA.

Central airway obstruction due to the tumor can present as near-complete tracheal obstruction. The results can be life-threatening requiring emergent intervention. Rigid bronchoscopy has been preferred for the management of central airway obstruction. Read More

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Spontaneous Massive Intrarenal Hemorrhage in a Patient With De Novo Ureteropelvic Junction Obstruction.

Cureus 2021 May 8;13(5):e14904. Epub 2021 May 8.

Department of Urology, San Fernando General Hospital, San Fernando, TTO.

This case represents an even rarer presentation of ureteropelvic junction obstruction (UPJO), that of a spontaneous life-threatening hemorrhage into the renal pelvis of a patient with previously unknown UPJO. Unique to this patient was the emergent nature of the presentation, requiring life-saving surgery. A review of the literature follows a discussion of the case. Read More

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Graphene Oxide Functionalized Double-Layered Patch with Anti-Adhesion Ability for Abdominal Wall Defects.

Int J Nanomedicine 2021 3;16:3803-3818. Epub 2021 Jun 3.

Department of Plastic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People's Republic of China.

Background: Effective repair of full-thickness abdominal wall defects requires a patch with sufficient mechanical strength and anti-adhesion characteristics to avoid the formation of hernias and intra-abdominal complications such as intestinal obstruction and fistula. However, patches made from polymers or bio-derived materials may not meet these requirements and lack the bionic characteristics of the abdominal wall.

Materials And Methods: In this study, we report a consecutive electrospun method for preparing a double-layer structured nanofiber membrane (GO-PCL/CS-PCL) using polycaprolactone (PCL), graphene oxide (GO) and chitosan (CS). Read More

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A Bayesian Latent Class Model to Predict Kidney Obstruction in the Absence of Gold Standard.

J Am Stat Assoc 2020 6;115(532):1645-1663. Epub 2020 Jan 6.

Department of Biostatistics, Epidemiology, and Informatics, University of Pennsylvania.

Kidney obstruction, if untreated in a timely manner, can lead to irreversible loss of renal function. A widely used technology for evaluations of kidneys with suspected obstruction is diuresis renography. However, it is generally very challenging for radiologists who typically interpret renography data in practice to build high level of competency due to the low volume of renography studies and insufficient training. Read More

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January 2020

MiR-124 and miR-506 are involved in the decline of protein C in children with extra-hepatic portal vein obstruction.

Sci Rep 2021 Jun 10;11(1):12320. Epub 2021 Jun 10.

Department of General Surgery, Capital Institute of Pediatrics, No. 2 Yabaolu Rd., Beijing, 100020, People's Republic of China.

The deficiency of protein C (PROC) can be partly rescued by Rex shunt through restoring portal blood flow in children with extra-hepatic portal venous obstruction (EHPVO). However, the decline of PROC is still found in some patients with a normal portal blood flow after Rex shunt. The aim of this study was to identify the candidate miRNAs involving in the decline of PROC and their mechanism. Read More

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Acute fasciolosis in an alpaca: a case report.

BMC Vet Res 2021 Jun 10;17(1):215. Epub 2021 Jun 10.

University College Dublin, Belfield, Dublin 4, D04W6F6, Ireland.

Background: The popularity of new world camelids, particularly alpacas, is growing rapidly in Ireland, presenting a clinical challenge to veterinary practitioners who may not have worked with these species previously. To the authors' knowledge, the clinical course of a case of acute fasciolosis in an alpaca has not previously been reported, and fasciolosis has not been reported at all in alpacas in Ireland, making this case report a valuable addition to the current literature.

Case Presentation: A three-year-old male castrated huacaya alpaca was admitted to UCD Veterinary Hospital with a two-day history of colic and tenesmus. Read More

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Correlation between body mass index and prostate volume in benign prostatic hyperplasia patients undergoing holmium enucleation of the prostate surgery.

BMC Urol 2021 Jun 10;21(1):88. Epub 2021 Jun 10.

Department of Urology, The University of Arizona, 1501 N Campbell Ave, PO Box 245077, Tucson, AZ, 85724-5077, USA.

Background: Benign prostatic obstruction (BPO) due to benign prostatic hyperplasia (BPH) is a leading cause of morbidity in men over the age of 40. This study examined whether there was an association between body mass index (BMI) and pre-operative prostate volume and whether expression of two genes, alpha-2-macroglobulin (A2M) and transforming growth factor beta 3 (TGFB3), was correlated with BMI, pre-operative prostate volume, and age at surgery.

Methods: Medical records of patients who underwent holmium enucleation of the prostate surgery for treatment of BPO were retrospectively reviewed. Read More

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Guidelines on analgosedation, monitoring, and recovery time for flexible bronchoscopy: a systematic review.

BMC Pulm Med 2021 Jun 10;21(1):198. Epub 2021 Jun 10.

Lung Clinic Cologne-Merheim, Thoracic Surgery, Hospital of Cologne, University of Witten/Herdecke, Ostmerheimer Str. 200, 51109, Cologne, Germany.

Background: Patients undergoing bronchoscopy in spontaneous breathing are prone to hypoxaemia and hypercapnia. Sedation, airway obstruction, and lung diseases impair respiration and gas exchange. The restitution of normal respiration takes place in the recovery room. Read More

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Prognostic value of C-reactive protein to albumin ratio for long-term outcomes of patients with peripheral arterial disease underwent endovascular treatment.

Vascular 2021 Jun 10:17085381211025172. Epub 2021 Jun 10.

Department of Cardiology, Medical Faculty, M.D. Kafkas University, Kars, Turkey.

Background: Peripheral artery disease (PAD) is part of the systemic atherosclerotic process that is highly associated with cardiovascular diseases. Despite successful endovascular treatment (EVT) strategies, mortality and morbidity rates still remain higher in PAD patients. C-reactive protein (CRP) and albumin are biomarkers of inflammation and malnutrition that play key roles in the progression of peripheral arterial disease. Read More

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Differential diagnosis of the association of gastrointestinal symptoms and ST segment elevation, in the absence of chest pain.

Oscar M P Jolobe

Am J Emerg Med 2021 Jun 4;49:137-141. Epub 2021 Jun 4.

British Medical Association, Flat 6 Souchay Court, 1 Clothorn Road, Manchester M20 6BR, United Kingdom. Electronic address:

This is a review of the underlying causes of the association of ST segment elevation and gastrointestinal symptoms such as abdominal pain, nausea, vomiting, and anorexia, in patients who do not have chest pain. The review was based on anecdotal reports in Googlescholar and Pubmed using the search terms, abdominal pain, nausea, vomiting, anorexia, ST elevation, myocardial infarction, and Takotsubo cardiomyopathy. Those patients who did not have acute myocardial infarction as the cause of the association of ST segment elevation and gastrointestinal symptoms were compared with counterparts with similar symptoms who had well authenticated acute myocardial infarction or Takotsubo cardiomyopathy as the underlying cause of ST segment elevation. Read More

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High Peak Inspiratory Pressures After a Change of Heat and Moisture Exchangers: A Case Series.

A A Pract 2021 Jun 10;15(6):e01483. Epub 2021 Jun 10.

From the Department of Anesthesiology and Perioperative Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

Elevated peak inspiratory pressures (PIPs) cause harm via hypoventilation, barotrauma, and hemodynamic instability. Heat and moisture exchangers (HMEs) are used during mechanical ventilation to prevent heat loss, dehydration of airway mucosa, and accumulation of dried secretions. Multiple reports detail sudden HME occlusions causing increased PIPs. Read More

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Prospective multicenter evaluation of moving cell metallic stents in endoscopic multiple stent deployment for hepatic hilar obstruction.

J Hepatobiliary Pancreat Sci 2021 Jun 10. Epub 2021 Jun 10.

TSOZ Pancreatobiliary Study Group, Osaka, Japan.

Background And Aim: Bilateral stent deployment for malignant biliary obstruction (MHBO) can be achieved using side-by-side (SBS) or stent-in-stent (SIS) procedures. Compared with SBS techniques, the procedural steps of SIS are technically complex due to the necessity of introducing the delivery system into a contralateral biliary tract through the mesh of the SEMS. To overcome this issue, a novel uncovered SEMS, the HILZO Moving Cell Stent (MCS) has been released. Read More

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Anatomical patterns of biliary atresia including hepatic radicles at the porta hepatis influence short- and long-term prognoses.

J Hepatobiliary Pancreat Sci 2021 Jun 10. Epub 2021 Jun 10.

Mashiko Memorial Hospital, Aichi Prefecture, 35-28 Takebashi-cho, Nakamura-ku, Nagoya, Japan, 4538566.

Background/purpose: The biliary atresia (BA) inflammatory process leads to various obstructive patterns of extrahepatic biliary trees. The significance of the various BA obstructive patterns is unclear. This study aimed to determine the relationship between the anatomical patterns of the biliary tract and short- and long-term prognoses in BA. Read More

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