1,698 results match your criteria Obstetrics and Gynecology Clinics of North America [Journal]


Innovation and Progress in Gynecologic Cancer Care: Faster than Ever.

Authors:
Carolyn Y Muller

Obstet Gynecol Clin North Am 2019 03;46(1):xv-xvi

Gynecologic Oncology, University of New Mexico, Comprehensive Cancer Center, 1 University of New Mexico, MSC 07 4025, Albuquerque, NM 87131, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ogc.2018.11.001DOI Listing
March 2019
3 Reads

Gynecologic Cancer Care: Innovative Progress.

Obstet Gynecol Clin North Am 2019 03;46(1):xiii-xiv

Department of Obstetrics and Gynecology, Office of Continuing Medical Education and Professional Development, University of New Mexico School of Medicine, MSC10 5580, 1 University of New Mexico, Albuquerque, NM 87131-0001, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ogc.2018.11.002DOI Listing
March 2019
2 Reads

Endometrial Cancer: Obesity, Genetics, and Targeted Agents.

Obstet Gynecol Clin North Am 2019 Mar;46(1):89-105

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Iowa, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA. Electronic address:

It is imperative to understand the underlying mechanisms of both endometrial carcinogenesis and recurrence in order to develop more effective prevention and treatment. This article reviews available molecular data, the interplay between endometrial cancer carcinogenesis with obesity and genetics, as well as current targeted therapies. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.09.006DOI Listing

Ovarian Cancer: Clinical Trial Breakthroughs and Impact on Management.

Obstet Gynecol Clin North Am 2019 Mar;46(1):67-88

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Duke Cancer Institute, Duke University Medical Center, Box 3079, Durham, NC 27710, USA.

Ovarian cancer treatment continues to evolve. Despite aggressive surgery and chemotherapy, most women will ultimately die from disease. Improvement in disease control are due to the incorporation of molecular targeted agents and the adoption of maintenance therapy. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.09.005DOI Listing
March 2019
2 Reads

Less Is More: Minimally Invasive and Quality Surgical Management of Gynecologic Cancer.

Obstet Gynecol Clin North Am 2019 Mar;46(1):55-66

Program in Women' Oncology, Women and Infants Hospital, 101 Dudley Street, Providence, RI 02905, USA.

Surgery is a cornerstone of gynecologic oncology. Minimally invasive techniques have been adopted rapidly, in lieu of open approaches, in cervical and endometrial cancer staging. In addition, nodal assessment has undergone significant changes with the introduction of SLN biopsies. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.09.004DOI Listing

Germline and Somatic Tumor Testing in Gynecologic Cancer Care.

Obstet Gynecol Clin North Am 2019 Mar;46(1):37-53

University of California, Irvine, 333 The City Boulevard, Suite 1400, Orange, CA 92868, USA.

New technologies have advanced the science of tumor biology and genomics. Commercially available germline and somatic testing modalities have the downstream benefits of enabling prevention strategies in women with hereditary cancers and their family members in addition to identifying women who benefit most from novel targeted therapeutics. The matrix of available testing is complex and evolving. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.09.003DOI Listing
March 2019
4 Reads

Cancer Screening and Prevention Highlights in Gynecologic Cancer.

Obstet Gynecol Clin North Am 2019 Mar;46(1):19-36

Division of Gynecology Oncology, Department of Obstetrics and Gynecology, University of Virginia, University of Virginia Medical Center, PO Box 800712, Charlottesville, VA 22908, USA.

This article provides an up-to-date summary of screening approaches and key strategies in prevention of gynecologic malignancies. The Pap smear is the only proven screening intervention in the field of gynecologic oncology. Women should receive treatment for precancerous conditions of the cervix, vulva, vagina, and endometrial lining. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.09.002DOI Listing
March 2019
8 Reads

Palliative Care in Gynecologic Oncology.

Obstet Gynecol Clin North Am 2019 Mar;46(1):179-197

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Washington University School of Medicine, Alvin J. Siteman Cancer Center, 660 South Euclid Avenue, Mail Stop 8064-37-905, St Louis, MO 63110, USA. Electronic address:

The integration of palliative care and hospice into standard gynecologic oncology care is associated with cost-savings, longer survival, lower symptom burden, and better quality of life for patients and caregivers. Consequently, this comprehensive approach is formally recognized and endorsed by the Society of Gynecologic Oncology, the National Comprehensive Cancer Network, and the American Society of Clinical Oncology. This article reviews the background, benefits, barriers, and most practical delivery models of palliative care. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.10.001DOI Listing
March 2019
1 Read

Gynecologic Cancer Survivorship.

Authors:
Elizabeth Lokich

Obstet Gynecol Clin North Am 2019 Mar;46(1):165-178

Division of Gynecologic Oncology, Women and Infants Hospital, Warren Alpert Medical School at Brown University, 101 Dudley Street, Providence, RI 02905, USA. Electronic address:

Survivorship care includes surveillance and prevention of cancer recurrence, addressing side effects of cancer and cancer treatment and coordination of follow-up care. This article reviews guidelines for surveillance of women with ovarian, endometrial, cervical, and vulvar cancer. It also reviews many of the long-term physical side effects of gynecologic cancer treatment including fatigue, neuropathy, lymphedema, cognitive dysfunction, sexual health concerns, menopausal symptoms, infertility, and economic stressors. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.10.002DOI Listing
March 2019
2 Reads

Personalized Medicine in Gynecologic Cancer: Fact or Fiction?

Obstet Gynecol Clin North Am 2019 Mar;46(1):155-163

Department of Gynecologic Oncology, Ochsner Clinic Foundation, 2700 Napoleon Avenue, New Orleans, LA 70115, USA.

Personalized medicine in gynecologic oncology is an evolving field. In recent years, tumor profiling and large databases such as TCGA and NCI-Match have provided us with enormous amounts of molecular data. Several therapies that capitalize on novel genetic and immune discoveries including VEGF inhibitors, PARP inhibitors, and cancer vaccinations are discussed in this article. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.09.010DOI Listing
March 2019
3 Reads

Chemotherapy, Biologic, and Immunotherapy Breakthroughs in Cancer Care.

Obstet Gynecol Clin North Am 2019 Mar;46(1):137-154

Department of Obstetrics and Gynecology, Uniformed Services University of the Health Sciences, 9618 Alta Vista Terrace, Bethesda, MD 20814, USA. Electronic address:

As the understanding of cancer biology expands, a wider array of treatment options has become available in the field of gynecologic cancer. Therapies that target specific molecular pathways are now being used. Drugs that target cancer angiogenesis, signal transduction, DNA repair, and immune evasion mechanisms are currently being used, in addition to or in lieu of traditional chemotherapy, to achieve more personalized treatment of each patient and their unique disease. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.09.009DOI Listing
March 2019
6 Reads

Vulvar Cancer.

Obstet Gynecol Clin North Am 2019 Mar;46(1):125-135

Department of Obstetrics and Gynecology, University of New Mexico, MSC10 5580, 1 University of New Mexico, Albuquerque, NM 87131, USA.

This article reviews the epidemiology, diagnosis, and management of vulvar preinvasive lesions, squamous cell carcinoma, and melanoma. There is an emphasis on sentinel lymph node dissection for early stage disease and advances in chemoradiation for late-stage disease. A brief review of vulvar Paget disease is also included. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.09.008DOI Listing
March 2019
5 Reads

(At Least) Once in Her Lifetime: Global Cervical Cancer Prevention.

Obstet Gynecol Clin North Am 2019 Mar;46(1):107-123

Department of Epidemiology and Population Health, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Belfer 1308A, Bronx, NY 10461, USA.

Cervical cancer disproportionately burdens lower-resourced settings, in which nearly 90% of cervical cancer and cervical cancer-related deaths occur. Targeting human papillomavirus (HPV) by prophylactic HPV vaccination in young adolescent girls and HPV-based screening in mid-adult women offers the most cost-effective strategy to reduce cervical cancer burden worldwide and mitigate the health disparities in cervical cancer burden between low-resourced and high-resourced settings. Political and social will, along with the necessary financial investments, will be necessary to realize the opportunity for significant global reductions in the cervical cancer burden. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.09.007DOI Listing

Current Quality of Gynecologic Cancer Care in North America.

Obstet Gynecol Clin North Am 2019 Mar;46(1):1-17

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, McMaster University, Juravinski Cancer Centre, 699 Concession Street, Hamilton, Ontario L8V 5C2, Canada. Electronic address:

Evaluating the quality of care received by gynecologic cancer patients in the real world is essential for excellent outcomes. The recent population-based literature looking at quality of care was reviewed for all gynecologic malignancies. Outcomes are generally highest when care is provided by high-volume providers in high-volume cancer centers. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.09.001DOI Listing

The Disruptive Changes of Midlife: A Biopsychosocial Adventure.

Obstet Gynecol Clin North Am 2018 12 25;45(4):xv-xvii. Epub 2018 Oct 25.

Psychiatry and Preventive Medicine, Rush Medical College, Rush University Medical Center, 2150 West Harrison Street, Room 278, Chicago, IL 60612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ogc.2018.08.001DOI Listing
December 2018
7 Reads

A More Complete Picture of Reproductive Aging and the Menopause Transition.

Obstet Gynecol Clin North Am 2018 12 25;45(4):xiii-xiv. Epub 2018 Oct 25.

Department of Obstetrics and Gynecology, Continuing Medical Education and Professional Development, University of New Mexico School of Medicine, MSC10 5580, 1 University of New Mexico, Albuquerque, NM 87131-0001, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ogc.2018.08.002DOI Listing
December 2018

Cognitive Changes with Reproductive Aging, Perimenopause, and Menopause.

Obstet Gynecol Clin North Am 2018 Dec 25;45(4):751-763. Epub 2018 Oct 25.

Division of Geriatrics, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison Geriatric Research Education and Clinical Center (GRECC) (11G), Wm S. Middleton Memorial Veterans Hospital, 2500 Overlook Terrace, Madison, WI 53706, USA.

This article reviews the role of endogenous estrogen in neural and cognitive processing, followed by an examination of longitudinal cognitive data captured in various stages of the menopausal transition. The remaining text reviews the contradictory results from major hormone therapy trials to date, evidence for the "timing hypothesis," and closes with recommendations for future research and for practicing clinicians. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.07.011DOI Listing
December 2018
2 Reads

Genitourinary Changes with Aging.

Obstet Gynecol Clin North Am 2018 Dec 25;45(4):737-750. Epub 2018 Oct 25.

Department of Obstetrics and Gynecology, University of California, Davis, 4860 Y Street, Suite 2500, Sacramento, CA 95817, USA. Electronic address:

Both chronologic aging and menopause affect the physical, physiologic, and microbiological characteristics of the genitourinary tract. The genitourinary syndrome of menopause, characterized by vulvovaginal and lower urinary tract signs and symptoms, is prevalent and has a significant negative impact on women's lives. In this article, the authors detail the genitourinary tract changes associated with menopause and/or aging. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.07.010DOI Listing
December 2018
17 Reads

Physical Activity and Physical Function: Moving and Aging.

Obstet Gynecol Clin North Am 2018 Dec 25;45(4):723-736. Epub 2018 Oct 25.

Department of Epidemiology, University of Michigan, School of Public Health, 1415 Washington Heights, Room 6618, Ann Arbor, MI 48109-2029, USA.

Evidence supports that the physical disablement process starts earlier than previously thought, in midlife when women still have many years to live. Physical activity participation and interventions have been successful in preventing disability in older adults and may be promising for maintaining function at younger ages. Changing the conversation to more relevant topics in midlife, like positive changes in body composition, sleep, and improved mood, may move the dial on participation, as midlife women do not meet guidelines for physical activity. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08898545183006
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http://dx.doi.org/10.1016/j.ogc.2018.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226270PMC
December 2018
20 Reads

Female Sexual Function at Midlife and Beyond.

Obstet Gynecol Clin North Am 2018 Dec 25;45(4):709-722. Epub 2018 Oct 25.

Department of Population Health Sciences, University of Utah, 295 Chipeta Way 1N492, Salt Lake City, UT 84108, USA; Department of Internal Medicine, University of Utah, 295 Chipeta Way 1N492, Salt Lake City, UT 84108, USA.

Sexual function is an important component of quality of life for women. Midlife poses several challenges to optimal sexual function and intimacy for women. In addition to anatomic factors related to estrogen deficiency, such as genitourinary syndrome of menopause, vulvovaginal atrophy, and pelvic organ prolaps, psychosocial factors, including prior sexual trauma, play an important role in sexual function in women. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.07.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226268PMC
December 2018
12 Reads
1.400 Impact Factor

Bone Health During the Menopause Transition and Beyond.

Obstet Gynecol Clin North Am 2018 Dec 25;45(4):695-708. Epub 2018 Oct 25.

Division of General Internal Medicine and Health Services Research, David Geffen School of Medicine at UCLA, 911 Broxton Avenue, 1st floor, Los Angeles, CA 90024, USA.

The menopause transition is a critical period for bone health, with rapid losses in bone mass and strength occurring in a 3-year window bracketing the date of the final menstrual period. Declines in bone mass are accompanied by deleterious changes in bone macrostructure and microarchitecture, which may be captured by changes in composite strength indices and indices of trabecular thickness and connectivity. The onset of the rapid bone loss phase is preceded by changes in sex steroid hormones and increases in markers of bone resorption, measurements of which may be clinically useful in predicting the onset of the rapid loss phase and in identifying the women who will lose the most bone strength over the menopause transition. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226267PMC
December 2018
13 Reads

Sleep, Health, and Metabolism in Midlife Women and Menopause: Food for Thought.

Obstet Gynecol Clin North Am 2018 Dec 25;45(4):679-694. Epub 2018 Oct 25.

Department of Psychiatry and Connors Center for Women's Health, Brigham and Women's Hospital, Dana Farber Cancer Institute, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

Sleep and metabolism are essential components of health. Metabolic health depends largely on individual's lifestyle. Disturbances in sleep health, such as changes in sleep patterns that are associated with menopause/reproductive aging and chronologic aging, may have metabolic health consequences. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338227PMC
December 2018
12 Reads

Depression During and After the Perimenopause: Impact of Hormones, Genetics, and Environmental Determinants of Disease.

Obstet Gynecol Clin North Am 2018 Dec 25;45(4):663-678. Epub 2018 Oct 25.

Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, 3535 Market Street, Philadelphia, PA, 19104, USA; Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, 3535 Market Street, Philadelphia, PA, 19104, USA; Penn PROMOTES Research on Sex and Gender in Health, University of Pennsylvania, 3535 Market Street, Philadelphia, PA, 19104, USA.

Vulnerability to depression is increased across the menopause transition and in the early years after the final menstrual period. Clinicians should systematically screen women in this age group; if depressive symptoms or disorder are present, treatment of depression should be initiated. Potential treatments include antidepressants for moderate to severe symptoms, psychotherapy to target psychological and interpersonal factors, and hormone therapy for women with first-onset major depressive disorder or elevated depressive symptoms and at low risk for adverse effects. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226029PMC
December 2018
7 Reads

Cardiovascular Implications of the Menopause Transition: Endogenous Sex Hormones and Vasomotor Symptoms.

Obstet Gynecol Clin North Am 2018 Dec 25;45(4):641-661. Epub 2018 Oct 25.

Departments of Psychiatry and Epidemiology, School of Medicine, Graduate School of Public Health, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA 15213, USA.

The menopause transition (MT) is a critical period of women's lives marked by several physiologic changes and menopause-related symptoms that have implications for health. Risk for cardiovascular disease, the leading cause of death in women, increases after menopause, suggesting a contribution of the MT to its development. This article focuses on the relationship between 2 main features of the MT and women's cardiovascular health: (1) dynamic alterations of sex hormones, particularly endogenous estradiol and follicle-stimulating hormone, and (2) vasomotor symptoms, the cardinal symptom of the menopause. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.07.006DOI Listing
December 2018
12 Reads

Vasomotor Symptoms Across the Menopause Transition: Differences Among Women.

Obstet Gynecol Clin North Am 2018 Dec 25;45(4):629-640. Epub 2018 Oct 25.

The Saul R. Korey Department of Neurology, Albert Einstein College of Medicine, Jack and Pearl Resnick Campus, 1300 Morris Park Avenue Block, Room 316, Bronx, NY 10461, USA.

Vasomotor symptoms (VMS) are the primary menopausal symptoms, occurring in up 80% of women and peaking around the final menstrual period. The average duration is 10 years, longer in women with an earlier onset. Compared with non-Hispanic white women, black and Hispanic women are more likely and Asian women are less likely to report VMS. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226273PMC
December 2018
7 Reads

Menstrual Cycle Hormone Changes Associated with Reproductive Aging and How They May Relate to Symptoms.

Obstet Gynecol Clin North Am 2018 Dec 25;45(4):613-628. Epub 2018 Oct 25.

Department of Obstetrics and Gynecology, University of Colorado School of Medicine, 12631 East 17th Avenue, Mail Stop B-198, Aurora, CO 80045, USA. Electronic address:

Key cycle changes occur as women transition from reproductive life to menopause, and they can be roughly linked to menopausal staging. It is important to understand the types of studies that inform the current knowledge. Patterns of symptoms within menstrual cycles (sleep, headache) generally favor worsening in association with the perimenstrual phase of the cycle, and patterns of chronic symptoms, such as hot flashes and adverse mood, appear to be worse when hormones are more variable. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226272PMC
December 2018
2 Reads

Menstrual Cycle Changes as Women Approach the Final Menses: What Matters?

Authors:
Siobán D Harlow

Obstet Gynecol Clin North Am 2018 Dec 25;45(4):599-611. Epub 2018 Oct 25.

Department of Epidemiology, School of Public Health of the University of Michigan, 1415 Washington Heights, Ann Arbor, MI 48109-2029, USA. Electronic address:

Increased variability in menstrual cycle length marks the onset of the menopausal transition, with the likelihood of long cycles increasing as women approach menopause. This article describes the STRAW+10 bleeding criteria for recognizing onset of the early and late menopausal transition, as well as the specific bleeding changes a woman may experience during this life stage, including how women's bleeding experiences differ. The high probability of episodes of excessive and prolonged bleeding as women approach their final menstrual period is documented, as is the continuing probability of ovulation as women reach their final menstrual period. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.07.003DOI Listing
December 2018
1 Read

Onset of the Menopause Transition: The Earliest Signs and Symptoms.

Obstet Gynecol Clin North Am 2018 Dec 25;45(4):585-597. Epub 2018 Oct 25.

Department of Obstetrics/Gynecology, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA; Department of Psychiatry, University of Pennsylvania School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104, USA.

Although more than 80% of women experience some degree of psychological or physical symptoms around menopause, both women and clinicians have misconceptions about how hormonal changes relate to menopausal symptoms and psychological conditions. Recently, several large-scale, longitudinal studies have been conducted to better characterize symptoms and changes that occur around menopause. This article offers current evidence for symptoms that occur in the early menopause transition, including vasomotor symptoms, mood changes, sleep problems, and changes in sexual functioning. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.07.002DOI Listing
December 2018
6 Reads

Declining Fertility with Reproductive Aging: How to Protect Your Patient's Fertility by Knowing the Milestones.

Obstet Gynecol Clin North Am 2018 Dec 25;45(4):575-583. Epub 2018 Oct 25.

Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, 550 16th Street, 7th Floor, San Francisco, CA 94158-2519, USA. Electronic address:

Protection of fertility shares many of the same concepts as optimization of general health, such as smoking cessation, maintenance of a healthy body weight, and moderation of alcohol intake. Increasing attention has been placed on minimizing exposures to known reproductive toxicants. There are few conclusive data to support specific diet patterns or supplements for fertility. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.07.001DOI Listing
December 2018

Treatment of Peripartum Mental Health Disorders: An Essential Element of Prenatal Care.

Obstet Gynecol Clin North Am 2018 09 11;45(3):xv-xvi. Epub 2018 Jul 11.

Department of Obstetrics and Gynecology, Medical University of South Carolina, Clinical Science Building, 96 Jonathan Lucas Street, Charleston, SC 29425, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ogc.2018.06.001DOI Listing
September 2018
2 Reads

Pregnancy: An Opportune Time to Evaluate and Treat Mental Health Disorders.

Obstet Gynecol Clin North Am 2018 09 11;45(3):xiii-xiv. Epub 2018 Jul 11.

Department of Obstetrics and Gynecology, Continuing Medical Education and Continuing Professional Development, University of New Mexico School of Medicine, MSC 10 5580, 1 University of New Mexico, Albuquerque, NM 87131-0001, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ogc.2018.06.002DOI Listing
September 2018

Psychosocial Aspects of Fertility and Assisted Reproductive Technology.

Obstet Gynecol Clin North Am 2018 Sep;45(3):563-574

Duke University Hospital, 2301 Erwin Road, Durham, NC 27710, USA.

Psychosocial aspects of fertility, infertility, and assisted reproductive technology (ART) can significantly impact patients' sense of self-identity and personal agency, mental well-being, sexual and marital relationships, reproductive efficiency, compliance with treatment, and pregnancy outcomes. Research is needed to understand how stress, anxiety, depression, mood disorders, and psychotropic medications impact fertility and infertility treatment. The psychosocial implications of ART on our society include a shift toward older maternal age at conception, the complexities of third-party reproduction, and consideration for the psychological and socioeconomic barriers to receiving care. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08898545183004
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http://dx.doi.org/10.1016/j.ogc.2018.04.006DOI Listing
September 2018
15 Reads

The Unwelcome Guest: Working with Childhood Sexual Abuse Survivors in Reproductive Health Care.

Obstet Gynecol Clin North Am 2018 Sep;45(3):549-562

Prospicare, 555 West Crosstown Parkway, Suite 403, Kalamazoo, MI 49008, USA. Electronic address:

Health care providers (HCPs) are often poorly prepared to respond to childhood sexual abuse (CSA) survivors' needs in reproductive health care. With few protocols addressing the CSA survivor population, HCPs struggle with delivering interventions that meet professional standards of care within the systemic constraints of reproductive health care. To bridge the gap that exists when the unwelcome guest of CSA enters the reproductive health care arena, it is important to understand the psychological influences of trauma that affect CSA survivors, the symptoms or behavioral cues that are commonly revealed, and therapeutic approaches that can facilitate positive patient-provider experiences in health care. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.04.009DOI Listing
September 2018

Perinatal Intimate Partner Violence.

Obstet Gynecol Clin North Am 2018 Sep;45(3):535-547

Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, National Crime Victims Research and Treatment Center (NCVRTC), 67 President Street, 2nd Floor South, MSC 861, Charleston, SC 29425-8610, USA.

This article reviews the prevalence and outcomes of perinatal intimate partner violence (IPV). Reported rates of perinatal IPV range from 3.7% to 9. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.04.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6089231PMC
September 2018

Impact of Pregnancy Loss on Psychological Functioning and Grief Outcomes.

Authors:
Tonia M Cassaday

Obstet Gynecol Clin North Am 2018 Sep;45(3):525-533

Department of Psychiatry, Medical University of South Carolina, 65 President Street, Charleston, SC 29425, USA. Electronic address:

This article discusses the prevalence and timing of perinatal loss. The impact that perinatal grief has on psychological functioning is presented, including common grief reactions and the risk factors for complicated grief. The ways that perinatal grief is processed by each parent and the impact that it has on the relationships is also discussed. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.04.004DOI Listing
September 2018
12 Reads

Treatment of Perinatal Opioid Use Disorder.

Obstet Gynecol Clin North Am 2018 Sep;45(3):511-524

Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, MSC 861, 67 President Street, Charleston, SC 29403, USA; Department of Obstetrics and Gynecology, Medical University of South Carolina, MSC 861, 67 President Street, Charleston, SC 29403, USA. Electronic address:

Opioid agonist therapy is the standard of care for pregnant women with Opioid Use Disorder, but medication-assisted withdrawal from opioid agonist therapy is increasingly prevalent. We review available literature evaluating the risks and benefits of medication-assisted withdrawal. We highlight the importance of supporting women in making an informed treatment choice that is best for them. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.05.001DOI Listing
September 2018
3 Reads

Management of Attention Deficit Hyperactivity Disorder During Pregnancy.

Obstet Gynecol Clin North Am 2018 Sep;45(3):495-509

Perinatal and Reproductive Psychiatry Program, Harvard Medical School, CTNI, Women's Mental Health, Massachusetts General Hospital, 185 Cambridge Street, 2nd Floor, Boston, MA 02114, USA.

Attention deficit hyperactivity disorder (ADHD) is a common neurobehavioral disorder affecting 3.2% of women. More women are taking psychostimulant medications, including during pregnancy. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.04.010DOI Listing
September 2018
5 Reads

Perinatal Sleep Problems: Causes, Complications, and Management.

Obstet Gynecol Clin North Am 2018 Sep;45(3):483-494

Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, MSC 861, Charleston, SC 29425, USA.

Changes in sleep are ubiquitous in the perinatal period and it is important to be able to determine when these changes are significant enough to indicate sleep deficiency associated with increased risk for poor maternal and infant outcomes. Guidelines for identifying sleep deficiency include insomnia symptoms, excessively shortened sleep duration, and perception of insufficient or nonrestful sleep. Causes and complicating factors related to such sleep problems have been well-documented and are used to tailor behavioral and pharmacologic treatments for women who are pregnant or in the early postpartum period. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.04.003DOI Listing
September 2018
2 Reads

Identification and Treatment of Peripartum Anxiety Disorders.

Obstet Gynecol Clin North Am 2018 Sep;45(3):469-481

Department of Psychiatry, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242, USA. Electronic address:

Anxiety disorders in the peripartum period are common and frequently overlooked. They can present de novo or as exacerbations of generalized anxiety disorder, obsessive compulsive disorder, panic disorder and social anxiety disorder, or posttraumatic stress disorder. Calculating a score on the Edinburgh postnatal depression scale is a useful method of screening for these disorders while also screening for perinatal depression. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.04.001DOI Listing
September 2018
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Recognizing and Managing Postpartum Psychosis: A Clinical Guide for Obstetric Providers.

Authors:
Lauren M Osborne

Obstet Gynecol Clin North Am 2018 Sep;45(3):455-468

Departments of Psychiatry & Behavioral Sciences and Gynecology & Obstetrics, Women's Mood Disorders Center, Johns Hopkins University School of Medicine, 550 North Broadway, Suite 305, Baltimore, MD 21205, USA. Electronic address:

Postpartum psychosis is a psychiatric emergency that affects 1 to 2 per 1000 women. Key clinical features include mood fluctuation, abnormal thoughts or behaviors, and confusion. Women with a history of bipolar disorder are at heightened risk, as are first-time mothers; current research on the causes focuses on biological triggers, such as immune dysregulation. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08898545183003
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http://dx.doi.org/10.1016/j.ogc.2018.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174883PMC
September 2018
12 Reads

Complementary Health Practices for Treating Perinatal Depression.

Obstet Gynecol Clin North Am 2018 Sep;45(3):441-454

Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, 700 Butler Drive, Providence, RI 02903, USA; Butler Hospital, 345 Blackstone Boulevard, Providence, RI 02906, USA; Center for Women's Behavioral Health, Women & Infants Hospital of Rhode Island, 2 Dudley Street, Providence, RI 02905, USA. Electronic address:

This article provides a focused review of the evidence for several complementary health approaches (ie, omega-3 fatty acids, folate, vitamin D, selenium, zinc, magnesium, B vitamins, physical activity, yoga) in the treatment of perinatal depression. There is evidence that some of these treatments may be reasonable to consider in women during pregnancy or the postpartum period. However, there are little data on the comparative safety and efficacy of these relative to traditional treatments (eg, psychotherapy, pharmacotherapy). Read More

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http://dx.doi.org/10.1016/j.ogc.2018.04.002DOI Listing
September 2018
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Pharmacologic Treatment of Perinatal Depression.

Obstet Gynecol Clin North Am 2018 Sep;45(3):419-440

Department of Psychiatry, University of North Carolina-Chapel Hill, Campus Box 7160, Chapel Hill, NC 27599-7160, USA.

This review provides information about medications used to treat perinatal depression, including guidance around when to use certain medications and when to consult a mental health provider. For each group of medications, including selective serotonin reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, mirtazapine, bupropion, lithium, atypical antipsychotics, and lamotrigine, the risks and benefits of treatment during pregnancy and lactation are reviewed, and unique qualities of each medication. A treatment algorithm is included and a description of the Food and Drug Administration's approach to providing information about medications. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08898545183004
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http://dx.doi.org/10.1016/j.ogc.2018.04.007DOI Listing
September 2018
32 Reads

Treatment of Peripartum Bipolar Disorder.

Obstet Gynecol Clin North Am 2018 Sep;45(3):403-417

Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, 676 St. Clair Street, Chicago, IL 60611, USA.

Bipolar disorder affects women throughout their childbearing years. During the perinatal period, women with bipolar disorder are vulnerable to depressive episode recurrences and have an increased risk for postpartum psychosis. Perinatal screening is critical to identify women at risk. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.05.002DOI Listing
September 2018

Medical Disorders in Pregnancy.

Obstet Gynecol Clin North Am 2018 06 15;45(2):xv-xvi. Epub 2018 Mar 15.

Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226-3522, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ogc.2018.02.003DOI Listing
June 2018
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Team-Based Care of Pregnant Women with Challenging Medical Disorders.

Obstet Gynecol Clin North Am 2018 06;45(2):xiii-xiv

Continuing Medical Education and Professional Development, University of New Mexico School of Medicine, MSC10 5580, 1 University of New Mexico, Albuquerque, NM 87131-0001, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ogc.2018.02.004DOI Listing
June 2018
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Thromboprophylaxis in Pregnancy.

Obstet Gynecol Clin North Am 2018 Jun;45(2):389-402

Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Tufts Medical Center, 800 Washington Street, Box 360, Boston, MA 02111, USA. Electronic address:

Venous thromboembolism is a leading cause of maternal morbidity and mortality worldwide. Identifying women who are at greatest risk for venous thromboembolism, and managing their pregnancies with appropriate thromboprophylaxis is essential to decreasing this life-threatening condition. Those at greatest risk are patients with thrombophilias, a personal or family history of venous thromboembolism, and those undergoing cesarean delivery. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.01.007DOI Listing
June 2018
2 Reads

Infections in Pregnancy and the Role of Vaccines.

Obstet Gynecol Clin North Am 2018 Jun;45(2):369-388

Department of Obstetrics and Gynecology, Obstetrics Clinical Research, Duke University Medical System, Durham, NC, USA.

Pregnant women are at risk for infection and may have significant morbidity or mortality. Influenza, pertussis, zika, and cytomegalovirus produce mild or asymptomatic illness in the mother, but have profound implications for her fetus. Maternal immunization can prevent or mitigate infections in pregnant women and their infants. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.01.006DOI Listing
June 2018
20 Reads

Seizures in Pregnancy.

Obstet Gynecol Clin North Am 2018 Jun;45(2):349-367

Department of Obstetrics, Gynecology and Women's Health, University of Missouri School of Medicine, 500 North Keene Street, Suite 406, Columbia, MO 65201, USA. Electronic address:

Seizures are among the most serious neurologic complications encountered in pregnancy. This review provides a foundation for the initial diagnosis, evaluation, classification, and management of seizures during pregnancy. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.02.001DOI Listing
June 2018
5 Reads

Hypertensive Disorders in Pregnancy.

Obstet Gynecol Clin North Am 2018 Jun;45(2):333-347

Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, University of Alabama at Birmingham, Women and Infants Center, 1700 6th Avenue South, Birmingham, AL 35249, USA.

Hypertensive disorders of pregnancy are a heterogeneous group of conditions that include chronic hypertension, gestational hypertension, preeclampsia, and preeclampsia superimposed on chronic hypertension. These disorders account for a significant proportion of perinatal morbidity and mortality nearly 10% of all maternal deaths in the United States. Given the substantial health burden of hypertensive disorders in pregnancy, there is increasing interest in optimizing management of these conditions. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.01.012DOI Listing
June 2018
4 Reads

Pregestational Diabetes in Pregnancy.

Obstet Gynecol Clin North Am 2018 Jun;45(2):315-331

Division of Maternal Fetal Medicine, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA. Electronic address:

Diabetes is a common chronic condition in women of reproductive age. Preconception care is crucial to reducing the risk of adverse maternal and fetal outcomes, such as hypertensive disorders, abnormal fetal growth, traumatic delivery and stillbirth, associated with poor glycemic control. Insulin is the preferred medication to optimize glucose control in women with pregestational diabetes. Read More

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http://dx.doi.org/10.1016/j.ogc.2018.01.002DOI Listing
June 2018
1 Read