62,785 results match your criteria Obstetrics Gynaecology & Reproductive Medicine [Journal]


Combined laparoscopic uterine artery occlusion and myomectomy versus laparoscopic myomectomy: a direct-comparison meta-analysis of short- and long term outcomes in women with symptomatic leiomyomas.

J Minim Invasive Gynecol 2019 Feb 15. Epub 2019 Feb 15.

Department of Gynaecology and Gynaecological Oncology, Guy's and St Thomas' NHS Foundation Trust, King's College, London, UK.

Objective: To ascertain the efficacy and safety of laparoscopic uterine artery occlusion (LUAO) during laparoscopic myomectomy (LM) on the intra- and post-operative morbidity and to assess its impact on leiomyomas recurrence rate.

Data Sources: MEDLINE, Scopus, Web of Science and Cochrane Database were searched for relevant references from inception until December 2018, in line with PRISMA guidelines.

Methods Of Study Selection: Two authors screened for study eligibility and extracted data. Read More

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http://dx.doi.org/10.1016/j.jmig.2019.02.004DOI Listing
February 2019

The Link between Thyroid Autoimmunity, Depression and Bipolar Disorder.

Open Med (Wars) 2019 16;14:52-58. Epub 2019 Jan 16.

Department of Obstetrics and Gynaecology, Lithuanian University of Health Sciences, Kaunas, Lithuania.

Depression and bipolar disorder are two major psychiatric illnesses whose pathophysiology remains elusive. Newly emerging data support the hypothesis that the dysfunction of the immune system might be a potential factor contributing to the development of these mental disorders. The most common organ affected by autoimmunity is the thyroid; therefore, the link between autoimmune thyroid disorders and mental illnesses has been studied since the 1930s. Read More

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http://dx.doi.org/10.1515/med-2019-0008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371203PMC
January 2019

Planning, Implementing, and Running a Multicentre Preterm Birth Study with Biobank Resources in Brazil: The Preterm SAMBA Study.

Biomed Res Int 2019 16;2019:5476350. Epub 2019 Jan 16.

Department of Obstetrics and Gynecology, University of Campinas (UNICAMP), School of Medical Sciences, Campinas, SP, Brazil.

Background: Our aim was to describe the steps in planning, implementing, and running a multicentre cohort study of maternal and perinatal health using a high-quality biobank comprised of maternal serum, plasma, and hair samples collected from five sites in Brazil. The Preterm SAMBA study, conducted by the Brazilian Network for Studies on Reproductive and Perinatal Health, was an innovative approach used to identify women at higher risk for preterm birth. It is also of great importance in the study of other maternal and perinatal complications in the context of Brazil, which is a middle-income country. Read More

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http://dx.doi.org/10.1155/2019/5476350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354138PMC
January 2019

Parents and clinicians: partners in perinatal bereavement research -experiences from the International Stillbirth Alliance Conference 2017.

Res Involv Engagem 2019 1;5. Epub 2019 Feb 1.

1Pregnancy Loss Research Group, Irish Centre for Fetal and Neonatal Translational Research (INFANT), University College Cork, Cork, Ireland.

In recent years, there has been a global call to reduce the numbers of preventable stillbirths and increase public awareness about the incidence and impact of pregnancy loss. The lived experiences of bereaved parents have much to contribute to developing the research agenda and clinical care in pregnancy loss. The multidisciplinary Pregnancy Loss Research Group (PLRG) based at the INFANT Centre at University College Cork and Cork University Maternity Hospital, has an established practice of active engagement and participation of patient members. Read More

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http://dx.doi.org/10.1186/s40900-018-0137-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357380PMC
February 2019

Editorial.

Authors:
Bid Kumar

Ultrasound 2019 Feb 31;27(1). Epub 2019 Jan 31.

Department of Obstetrics and Gynaecology, Wrexham Maelor Hospital, Wrexham, UK.

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http://dx.doi.org/10.1177/1742271X19826768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362543PMC
February 2019

Effect of insulin or insulin-like growth factor-I administration at mid-luteal phase of the estrous cycle during superovulation on hormonal profile of Sahiwal cows.

Vet World 2018 Dec 27;11(12):1736-1741. Epub 2018 Dec 27.

Department of Veterinary Gynaecology and Obstetrics, College of Veterinary and Animal Sciences, Govind Ballabh Pant University of Agriculture and Technology, Pantnagar, Uttarakhand, India.

Aim: The present study was designed to study the effect of insulin and insulin-like growth factor-1 (IGF-I) administration during luteal phase of the estrous cycle on the hormonal profile of Sahiwal embryo donor cows during superovulation.

Materials And Methods: Cows (n=18) were selected and divided into three groups; control (n=6, untreated), T-I (n=6, insulin-treated), and T-II (n=6, IGF-I treated). Insulin and IGF-I were given S/C on 5, 6, 7, and 8 days of estrous cycle. Read More

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http://dx.doi.org/10.14202/vetworld.2018.1736-1741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362330PMC
December 2018

Sphenopalatine ganglion block: A newer modality for management of postdural puncture headache.

J Anaesthesiol Clin Pharmacol 2018 Oct-Dec;34(4):567-568

Department of Obstetrics and Gynaecology, Himalayan Hospital, Dehradun, Uttarakhand, India.

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http://dx.doi.org/10.4103/joacp.JOACP_64_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360880PMC
February 2019

Understanding and provision of preconception care by general practitioners.

Aust N Z J Obstet Gynaecol 2019 Feb 17. Epub 2019 Feb 17.

Charles Perkins Centre, The University of Sydney, Sydney, Australia.

Background: Preconception care (PCC) defines health interventions prior to conception aimed at improving pregnancy and infant outcomes.

Aim: To explore the understanding and provision of PCC by general practitioners (GPs) within the Sydney Local Health District.

Materials And Methods: A questionnaire developed with GPs assessed structure and content of PCC provided, attitudes toward PCC and perceived barriers and facilitators. Read More

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http://dx.doi.org/10.1111/ajo.12962DOI Listing
February 2019

Birth choices for women in a 'Positive Birth after Caesarean' clinic: Randomised trial of alternative shared decision support strategies.

Aust N Z J Obstet Gynaecol 2019 Feb 18. Epub 2019 Feb 18.

School of Nursing, University of Alabama at Birmingham, Birmingham, Alabama, USA.

Background: Systematic approaches to information giving and decision support for women with previous caesarean sections are needed.

Aim: To evaluate decision support within a 'real-world' shared decision-making model.

Methods: A pragmatic comparative effectiveness randomised trial in the Positive Birth After Caesarean Clinic. Read More

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http://dx.doi.org/10.1111/ajo.12955DOI Listing
February 2019

Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses.

Lancet 2019 Feb 14. Epub 2019 Feb 14.

Department of Women and Children's Health, King's College London, London, UK. Electronic address:

Background: Intrahepatic cholestasis of pregnancy is associated with adverse perinatal outcomes, but the association with the concentration of specific biochemical markers is unclear. We aimed to quantify the adverse perinatal effects of intrahepatic cholestasis of pregnancy in women with increased serum bile acid concentrations and determine whether elevated bile acid concentrations were associated with the risk of stillbirth and preterm birth.

Methods: We did a systematic review by searching PubMed, Web of Science, and Embase databases for studies published from database inception to June 1, 2018, reporting perinatal outcomes for women with intrahepatic cholestasis of pregnancy when serum bile acid concentrations were available. Read More

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http://dx.doi.org/10.1016/S0140-6736(18)31877-4DOI Listing
February 2019

Management of intrahepatic cholestasis in pregnancy.

Lancet 2019 Feb 14. Epub 2019 Feb 14.

Department of Obstetrics and Gynaecology, Monash University, Clayton, VIC 3168, Australia. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(18)32323-7DOI Listing
February 2019

Management of idiopathic recurrent pericarditis during pregnancy.

Int J Cardiol 2019 Feb 6. Epub 2019 Feb 6.

University Cardiology AOU, Città della Salute e della Scienza di Torino, Torino, Italy.

Background: Data concerning idiopathic recurrent pericarditis in pregnancy are scarce.

Objectives: To evaluate the management and outcome of idiopathic recurrent pericarditis during pregnancy.

Methods And Results: Twenty-one pregnancies were evaluated in fourteen women with a history of recurrent idiopathic pericarditis (mean maternal age 31. Read More

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http://dx.doi.org/10.1016/j.ijcard.2019.02.003DOI Listing
February 2019

Age at menarche and clinical outcomes following medically assisted reproduction (MAR): a cohort study.

Gynecol Endocrinol 2019 Feb 18:1-5. Epub 2019 Feb 18.

a Assisted Reproduction Unit, Third Department of Obstetrics and Gynecology , "Attikon Hospital ", Medical School, National and Kapodistrian University of Athens , Athens , Greece.

Medically assisted reproduction (MAR) technologies have advanced rapidly, but in contrast to the specificity of modern approaches, they provide limited effectiveness in the management of the infertile couple. The purpose of this study was to assess the possible relationship between age at menarche and MAR outcomes of clinical pregnancy, live birth and the adverse incident of miscarriage, and to determine the offspring sex ratio according to age at menarche. In a cohort of 254 infertile couples who underwent 426 IVF/ICSI cycles, statistical analysis was performed by applying Student's t-test, chi-square test, and logistic regression models, adequately in the respective parameters and outcomes. Read More

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http://dx.doi.org/10.1080/09513590.2018.1538344DOI Listing
February 2019

The effect of maternal body mass index (BMI) and telomere function on in vitro fertilization (IVF) outcome: a preliminary cohort study.

Hum Fertil (Camb) 2019 Feb 17:1-7. Epub 2019 Feb 17.

b Sackler School of Medicine , Tel Aviv University , Tel Aviv , Israel.

Telomeres are a specific base sequence of DNA, responsible for chromosome stability and DNA protection. We aimed to investigate the association between telomere systems and IVF outcomes according to patients' BMI. For all telomere characteristics, there was a distinct trend towards shorter telomeres and activation of telomere shortening compensatory mechanisms in the BMI group >25kg/m, reaching statistical significance for senescence only (r = 0. Read More

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http://dx.doi.org/10.1080/14647273.2019.1575988DOI Listing
February 2019

Current treatments for female primary stress urinary incontinence.

Climacteric 2019 Feb 18:1-7. Epub 2019 Feb 18.

a Department of Obstetrics and Gynaecology, Helsinki University Hospital , Helsinki University , Helsinki , Finland.

Stress urinary incontinence (SUI) affects millions of women worldwide. Pelvic floor muscle training is the first-line treatment for SUI, and if this fails, midurethral sling surgery has become the gold-standard treatment. More recently, complications from midurethral mesh slings, particularly chronic pain and dyspareunia, have become a major concern. Read More

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http://dx.doi.org/10.1080/13697137.2019.1568404DOI Listing
February 2019
1 Read

Macrophages infiltrating endometriosis-like lesions exhibit progressive phenotype changes in a heterologous mouse model.

J Reprod Immunol 2019 Jan 25;132:1-8. Epub 2019 Jan 25.

Robinson Research Institute and Adelaide Medical School, The University of Adelaide, Adelaide, SA 5000, Australia; The Women's and Children's Hospital, Department of Obstetrics and Gynaecology, North Adelaide, SA 5006, Australia. Electronic address:

Endometriotic lesion development involves complex interactions between endometrial tissue, the peritoneum and immune cells. Macrophages are essential in this process; however their precise roles are not defined. To investigate whether infiltrating macrophages acquire functionally different phenotypes during lesion development, human endometrial tissues were grafted into immunodeficient mice expressing macrophage-specific green fluorescent protein (GFP). Read More

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http://dx.doi.org/10.1016/j.jri.2019.01.002DOI Listing
January 2019

The European registry on obstetric Antiphospholipid syndrome (EUROAPS): A survey of 1000 consecutive cases.

Autoimmun Rev 2019 Feb 14. Epub 2019 Feb 14.

Obstetrics and Gynaecology Department, High Risk Unit, Vall d'Hebron University Hospital, Universitat Autonoma, Barcelona, Spain.

Aim To analyse the clinical features, laboratory data and foetal-maternal outcomes, and follow them up on a cohort of 1000 women with obstetric antiphospholipid syndrome (OAPS).

Methods: The European Registry of OAPS became a registry within the framework of the European Forum on Antiphospholipid Antibody projects and was placed on a website in June 2010. Thirty hospitals throughout Europe have collaborated to carry out this registry. Read More

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http://dx.doi.org/10.1016/j.autrev.2018.12.006DOI Listing
February 2019

Mortinaissance attribuable à l'ulcération du cordon ombilical.

J Obstet Gynaecol Can 2019 Feb 13. Epub 2019 Feb 13.

Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynaecology, and Reproductive Sciences, University of Manitoba, Winnipeg, MB.

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http://dx.doi.org/10.1016/j.jogc.2019.01.005DOI Listing
February 2019

Diagnosis of Fetal Multicystic Dysplastic Kidney in the First Trimester of Pregnancy by 2-D and 3-D Ultrasonography.

J Obstet Gynaecol Can 2019 Feb 13. Epub 2019 Feb 13.

Perinatal Service, Monash Medical Centre, Clayton, Victoria, Australia; Mercy Hospital for Women, Heidelberg, Victoria, Australia.

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http://dx.doi.org/10.1016/j.jogc.2018.05.028DOI Listing
February 2019

Diagnostic d'une dysplasie rénale multikystique fœtale au premier trimestre de grossesse par échographies 2D et 3D.

J Obstet Gynaecol Can 2019 Feb 13. Epub 2019 Feb 13.

Perinatal Service, Monash Medical Centre, Clayton, Victoria, Australia; Mercy Hospital for Women, Heidelberg, Victoria, Australia.

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http://dx.doi.org/10.1016/j.jogc.2018.08.007DOI Listing
February 2019

Oblitération de l'ostium vaginal secondaire au lichen scléreux.

J Obstet Gynaecol Can 2019 Feb 13. Epub 2019 Feb 13.

Department of Obstetrics and Gynaecology, Dalhousie University, Halifax, NS.

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http://dx.doi.org/10.1016/j.jogc.2019.01.006DOI Listing
February 2019

Introital Obliteration as a Consequence of Lichen Sclerosus.

J Obstet Gynaecol Can 2019 Feb 13. Epub 2019 Feb 13.

Department of Obstetrics and Gynaecology, Dalhousie University, Halifax, NS. Electronic address:

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http://dx.doi.org/10.1016/j.jogc.2018.11.009DOI Listing
February 2019

Stillbirth Due to Umbilical Cord Erosion.

J Obstet Gynaecol Can 2019 Feb 13. Epub 2019 Feb 13.

Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynaecology, and Reproductive Sciences, University of Manitoba, Winnipeg, MB.

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http://dx.doi.org/10.1016/j.jogc.2018.11.006DOI Listing
February 2019

Pro-endometriotic niche in endometriosis.

Reprod Biomed Online 2018 Dec 23. Epub 2018 Dec 23.

Department of Obstetrics and Gynaecology, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. Electronic address:

Endometriosis is a complex and heterogeneous disorder of unknown aetiology. This benign disease possesses special biological behaviours that mimic those of malignant tumours. A pro-endometriotic niche established by an existing lesion is a supportive micro-environment for the progression of endometriosis. Read More

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http://dx.doi.org/10.1016/j.rbmo.2018.12.025DOI Listing
December 2018

Prenatal diagnosis and management of congenital diaphragmatic hernia.

Best Pract Res Clin Obstet Gynaecol 2019 Jan 5. Epub 2019 Jan 5.

Academic Department of Development and Regeneration, Cluster Woman and Child, Biomedical Sciences, KU Leuven, Belgium; Clinical Department of Obstetrics & Gynaecology, KU Leuven, Leuven, Belgium; Institute for Women's Health, University College London, London, UK; European Reference Network on Rare and Inherited Congenital Anomalies "ERNICA". Electronic address:

Congenital diaphragmatic hernia is characterized by failed closure of the diaphragm, thereby allowing abdominal viscera to herniate into the thoracic cavity and subsequently interfering with normal lung development. At birth, pulmonary hypoplasia leads to respiratory insufficiency and persistent pulmonary hypertension (PHT), that is lethal in up to 32% of patients. In isolated cases, the outcome may be predicted prenatally by medical imaging and advanced genetic testing. Read More

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http://dx.doi.org/10.1016/j.bpobgyn.2018.12.010DOI Listing
January 2019
1 Read

Frequency and risk factors of thoracic metastases and optimisation of the use of cross-sectional chest imaging in follow-up patients with cervical cancer.

Clin Radiol 2019 Feb 13. Epub 2019 Feb 13.

Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.

Aim: To optimise cross-sectional chest imaging usage by identifying frequency and risk factors associated with thoracic metastases in cervical cancer patients after initial definitive treatment.

Materials And Methods: This study, conducted during 2004-2015, examined 361 consecutive patients with histopathologically proven cervical carcinoma with at least 1 year of follow-up. Electronic medical records and all available imaging modes were used to record and assess patient and tumour characteristics and timing of thoracic metastases. Read More

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http://dx.doi.org/10.1016/j.crad.2018.11.014DOI Listing
February 2019

Risk factors for pelvic and distant recurrence in locally advanced cervical cancer.

Eur J Obstet Gynecol Reprod Biol 2019 Feb 6;235:6-12. Epub 2019 Feb 6.

Medical Oncology Department, A.C. Camargo Cancer Center, São Paulo, SP, Brazil. Electronic address:

Objective: Despite the benefits of concomitant radiotherapy and cisplatin for locally advanced cervical cancer, recurrence rates remain high. New treatment strategies such as consolidation chemotherapy and different concomitant chemotherapy combinations have been tested in recent years. Identification of the best candidates for each treatment strategy could optimize results. Read More

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http://dx.doi.org/10.1016/j.ejogrb.2019.01.028DOI Listing
February 2019

Mobile obstetric and neonatal simulation based skills training in India.

Midwifery 2019 Feb 7;72:14-22. Epub 2019 Feb 7.

Department of Paediatrics, Monash University, Melbourne, Australia.

Background: The developing world has a significantly high risk of women and babies dying during childbirth. Interprofessional simulation training has improved birth practices and outcomes by impacting clinical and non-technical skills like communication, teamwork, leadership and effective use of resources. While these programs have become a training requirement in many high-income countries, they have not been widely introduced in the low-income, low-resource settings. Read More

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http://dx.doi.org/10.1016/j.midw.2019.02.006DOI Listing
February 2019

SIRT1 participates in the response to methylglyoxal-dependent glycative stress in mouse oocytes and ovary.

Biochim Biophys Acta Mol Basis Dis 2019 Feb 13. Epub 2019 Feb 13.

Department of Life, Health and Environmental Sciences, University of L'Aquila, L'Aquila, Italy; Infertility Service, San Salvatore Hospital, L'Aquila 67100, L'Aquila, Italy. Electronic address:

Methylglyoxal (MG), a highly reactive dicarbonyl derived from metabolic processes, is the most powerful precursor of advanced glycation end products (AGEs). Glycative stress has been recently associated with ovarian dysfunctions in aging and PCOS syndrome. We have investigated the role of the NAD-dependent Class III deacetylase SIRT1 in the adaptive response to MG in mouse oocytes and ovary. Read More

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http://dx.doi.org/10.1016/j.bbadis.2019.02.011DOI Listing
February 2019

The importance of non-technical performance for teams managing postpartum haemorrhage: video review of 99 obstetric teams.

BJOG 2019 Feb 16. Epub 2019 Feb 16.

School of Applied Psychology, University of Applied Sciences and Arts Northwestern Switzerland, Switzerland.

Objective: Little is known about how teams' non-technical performance influences clinical performance in obstetric emergencies like postpartum haemorrhage.

Design: Video review - observational study.

Setting: A university hospital (5,000 deliveries) and a regional hospital (2,000 deliveries) in Denmark. Read More

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http://dx.doi.org/10.1111/1471-0528.15655DOI Listing
February 2019
1 Read

Generation of immortalized human endometrial stromal cell lines with different endometriosis risk genotypes.

Mol Hum Reprod 2019 Feb 16. Epub 2019 Feb 16.

Department of Obstetrics and Gynaecology and Gynaecology Research Centre, Royal Women's Hospital, University of Melbourne, Parkville, Victoria, Australia.

Endometriotic lesions are composed in part of endometrial-like stromal cells, however, there is a shortage of immortalized human endometrial stromal cultures available for research. As genetic factors play a role in endometriosis risk, it is important that genotype is also incorporated into analysis of pathological mechanisms. Human telomerase reverse transcriptase (hTERT) immortalization (using Lenti-hTERT-green fluorescent protein virus) took place following genotype selection; 13 patients homozygous for either the risk or non-risk 'other' allele for one or more important endometriosis risk single nucleotide polymorphism on chromosome 1p36. Read More

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http://dx.doi.org/10.1093/molehr/gaz006DOI Listing
February 2019

Management of fetal tumors.

Best Pract Res Clin Obstet Gynaecol 2019 Jan 14. Epub 2019 Jan 14.

Fetal Medicine Unit, Department of Obstetrics and Gynaecology, Mount Sinai Hospital and University of Toronto, Toronto, Canada. Electronic address:

In this review article, we discuss the most common fetal tumors, their prenatal management, and outcomes. Overall, the most important outcome predictors are tumor histology, size, vascularity, and location. Very large lesions, lesions causing cardiac failure, and hydrops and lesions obstructing the fetal airway have the poorest outcome, as they may cause fetal death or complications at the time of delivery. Read More

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http://dx.doi.org/10.1016/j.bpobgyn.2019.01.006DOI Listing
January 2019
1 Read

Specific Decrease in B-Cell-Derived Extracellular Vesicles Enhances Post-Chemotherapeutic CD8 T Cell Responses.

Immunity 2019 Feb 6. Epub 2019 Feb 6.

Institute of Immunology and Department of Orthopaedics of the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China. Electronic address:

Systemic immunosuppression greatly affects the chemotherapeutic antitumor effect. Here, we showed that CD19 extracellular vesicles (EVs) from B cells through CD39 and CD73 vesicle-incorporated proteins hydrolyzed ATP from chemotherapy-treated tumor cells into adenosine, thus impairing CD8 T cell responses. Serum CD19 EVs were increased in tumor-bearing mice and patients. Read More

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http://dx.doi.org/10.1016/j.immuni.2019.01.010DOI Listing
February 2019

Imaging of postoperative endometriosis.

Diagn Interv Imaging 2019 Feb 12. Epub 2019 Feb 12.

Department of Radiology, Hôpital Tenon, 4, rue de la Chine, 75020 Paris, France.

Endometriosis is a chronic gynecological condition that affects primarily young women. Imaging plays a pivotal role for the diagnosis and pre-surgical mapping of the disease. By comparison, the role of imaging in the identification of disease recurrence and postoperative complications are not well established. Read More

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http://dx.doi.org/10.1016/j.diii.2018.11.003DOI Listing
February 2019

Maternal respiratory distress and successful reversal with sugammadex during intrauterine transfusion with fetal paralysis.

Int J Obstet Anesth 2019 Jan 8. Epub 2019 Jan 8.

Department of Obstetrics and Gynaecology, IWK Health Centre, Halifax, Nova Scotia, Canada.

A 70 kg, 34-year-old woman at 29 weeks-of-gestation required intrauterine transfusion for Rh (D) alloimmunization. In the ambulatory treatment clinic, 19 mg of rocuronium was administered intramuscularly in split doses into the fetal buttock. The fetus moved and inadvertent maternal neuromuscular blockade occurred, leading to respiratory distress. Read More

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http://dx.doi.org/10.1016/j.ijoa.2019.01.002DOI Listing
January 2019

Adherence and Concordance of Influenza and Pertussis Vaccination Coverage in Pregnant Women in Spain.

Int J Environ Res Public Health 2019 Feb 14;16(4). Epub 2019 Feb 14.

Unidad Mixta de Investigación para el Análisis de las Desigualdades en Salud y la Mortalidad FISABIO-UA, Departament of Community Health, Preventive Medicine and Public Health, and Science's History, University of Alicante, Carretera de San Vicente del Raspeig s/n, 03690 Alicante, Spain.

: Pregnant women should receive two vaccines during pregnancy due to maternal-foetal complications and risks as well as the influenza and pertussis vaccinations. The goal was to evaluate vaccination coverage against influenza and pertussis in pregnant women, following midwife professional advice during the pregnancy follow-up; : Prospective cohort study of 1017 pregnancies during the vaccination campaign in 2015⁻2016. To estimate the degree of consistency between the coverage declared by mothers and that registered in the Nominal Vaccination Registry (NVR), we used the Cohen's kappa index (k); : 95. Read More

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http://dx.doi.org/10.3390/ijerph16040543DOI Listing
February 2019

Assessment of optimal insulin administration timing for standard carbohydrates rich meals using continuous glucose monitoring in children with type 1 diabetes-crossover randomized study.

J Diabetes Investig 2019 Feb 15. Epub 2019 Feb 15.

Department of Children's Diabetology, Medical University Of Silesia, Katowice, Poland.

Objective: Assessment of postprandial glucose concentration after carbohydrates rich meals using continuous glucose monitoring in 30 children with type 1 diabetes treated using continuous subcutaneous insulin infusion with a rapid-acting analogs insulin.

Methods: During 3 days, participants administering simple boluses with different delay time between insulin administration and beginning of carbohydrates rich meals consumption (meal №1 containing - 197 kcal, №2 - 247 kcal and meal №3 - 323 kcal; practically not containing protein and fat). In our cross-over randomized study we analyzed: average glucose concentration profiles in 5-minutes intervals, mean glucose at insulin administration, after 120 and 180 minutes, mean and peak glucose, glucose peak time, areas under glucose and glucose increase curves, time period lengths with glucose below 50, 70 mg/dl and over 140, 200 mg/dl. Read More

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http://dx.doi.org/10.1111/jdi.13027DOI Listing
February 2019

A lower maternal cortisol to cortisone ratio precedes clinical diagnosis of preterm and term preeclampsia by many weeks.

J Clin Endocrinol Metab 2019 Feb 15. Epub 2019 Feb 15.

Department of Obstetrics and Gynaecology, NIHR Biomedical Research Centre, University of Cambridge, Cambridge, UK.

Context: Previous studies have shown reduced placental levels of 11-beta-hydroxysteroid dehydrogenase-type 2 (11βHSD2) in preeclampsia. However, it is not known if the maternal cortisol to cortisone ratio is predictive of placental complications of pregnancy.

Objective: To determine the relationship between the maternal serum cortisol to cortisone ratio at different stages of pregnancy and the risk of preeclampsia or fetal growth restriction (FGR). Read More

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http://dx.doi.org/10.1210/jc.2018-02312DOI Listing
February 2019

Therapeutic Potential of Endothelial Colony Forming Cells Derived from Human Umbilical Cord Blood.

Curr Stem Cell Res Ther 2019 Feb 14. Epub 2019 Feb 14.

Department of Obstetrics and Gynaecology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan. China.

Endothelial progenitor cells (EPCs) are implicated in mutiple biologic processes such as vascular homeostasis, neovascularization and tissue regeneration, and tumor angiogenesis. A subtype of EPCs is referred to as endothelial colony-forming cells (ECFCs), which display robust clonal proliferative potential and can form durable and functional blood vessels in animal models. In this review, we provide a brief overview of EPCs' characteristics, classification and origins, a summary of the progress in preclinical studies as regard to the therapeutic potential of human umbilical cord blood derived ECFCs (CB-ECFCs) for ischemia repair, tissue engineering and tumor, and highlight the necessity to select high proliferative CB-ECFCs and to optimize their recovery and expansion conditions. Read More

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http://dx.doi.org/10.2174/1574888X14666190214162453DOI Listing
February 2019

Hyperglycaemia cause vascular inflammation through advanced glycation end products/early growth response-1 axis in gestational diabetes mellitus.

Mol Cell Biochem 2019 Feb 14. Epub 2019 Feb 14.

School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, India.

Hyperglycaemia during pregnancy is the main reason for developing diabetes mediated vascular complications. Advanced glycation end products (AGEs) are formed due to non-enzymatic glycation of proteins, lipids and nucleic acids during hyperglycaemia. It has the potential to damage vasculature by modifying the substrate or by means of AGEs and receptor of AGE (RAGE) interaction. Read More

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http://dx.doi.org/10.1007/s11010-019-03503-0DOI Listing
February 2019

Bone mineral density in midlife long-term users of hormonal contraception in South Africa: relationship with obesity and menopausal status.

Womens Midlife Health 2018 10;4. Epub 2018 Apr 10.

1MatCH Research Unit [Maternal, Adolescent and Child Health Research Unit], Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of the Witwatersrand, 40 Dr AB Xuma Street,11th floor, Suite 1108-9,Commercial City, Durban, 4001 South Africa.

Background: In South Africa, hormonal contraception is widely used in women over the age of 40 years. One of these methods and the most commonly used is depot-medroxyprogesterone acetate (DMPA) which has been found to have a negative effect on bone mass. Limited information is available on the effect of norethisterone enanthate (NET-EN) on bone mass, and combined oral contraceptives (COCs) have not been found to be associated with loss of bone mass. Read More

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http://dx.doi.org/10.1186/s40695-018-0035-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6297953PMC

3D laparoscopy as a tertiary cytoreductive (TCR) surgery in infiltrating ureter recurrent epithelial ovarian cancer - case report and a mini-review of the literature.

Prz Menopauzalny 2018 Dec 31;17(4):185-188. Epub 2018 Dec 31.

Mazovia Hospital, Warsaw, Poland.

The paper describes a case of a 61-year-old woman with recurrent epithelial ovarian cancer infiltrating the ureter treated with 3D laparoscopy as a tertiary cytoreductive surgery (TCR). In addition, a mini-review of the literature concerning TCR is presented. Read More

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http://dx.doi.org/10.5114/pm.2018.81745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372846PMC
December 2018

Oestrogen receptor alpha PvuII polymorphism and uterine fibroid incidence in Caucasian women.

Prz Menopauzalny 2018 Dec 31;17(4):149-154. Epub 2018 Dec 31.

Department of Biochemistry and Pharmacogenomics, Faculty of Pharmacy with Division of Laboratory Medicine, Medical University of Warsaw, Warsaw, Poland.

Introduction: Uterine fibroids (UFs) are benign, monoclonal tumours of the female genital tract that originate from the myometrium. They may be diagnosed in as many as 80% of women depending on the selected population. UFs depend mostly on steroid hormones. Read More

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http://dx.doi.org/10.5114/pm.2018.81735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372853PMC
December 2018

Uterine artery embolization in the treatment of symptomatic fibroids - state of the art 2018.

Authors:
Anna Stępniak

Prz Menopauzalny 2018 Dec 31;17(4):141-143. Epub 2018 Dec 31.

3 Chair and Department of Gynaecology, Medical University of Lublin, Lublin, Poland.

Uterine fibroids are considered to be the most common benign tumours in females. The vast majority of these tumours are incidental findings and do not require any treatment. Symptomatic fibroids, with ailments such as abnormal uterine bleeding, dysmenorrhoea, pelvic pain, impaired urination, bowel dysfunction, infertility, and recurrent pregnancy loss, are indicated for medical treatment. Read More

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http://dx.doi.org/10.5114/pm.2018.81733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372851PMC
December 2018

Surgical Experience in Pediatric Patients with Chiari-I Malformations Aged ≤18 Years.

J Neurosci Rural Pract 2019 Jan-Mar;10(1):85-88

Department of Neurosurgery, Maharaja Agrasen Hospital, New Delhi, India.

Objective: The objective of this study was to retrospectively study Chiari I malformation patients (<18 years) treated surgically.

Materials And Methods: Chiari I malformation patients (<18 years) treated surgically at our institute were retrospectively studied.

Results: During the study period between January 1999 and June 2011, fifty patients, aged ≤18 years with Chiari malformation, were treated surgically and formed the basis for this series. Read More

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http://dx.doi.org/10.4103/jnrp.jnrp_160_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337998PMC
February 2019

Approach to sexual dysfunction in women with cancer.

Int J Gynecol Cancer 2019 Feb 13. Epub 2019 Feb 13.

Department of Obstetrics and Gynaecology, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy.

Sexual dysfunction in female cancer patients remains under-diagnosed and under-treated. As sexual dysfunction is becoming an increasingly common side effect of cancer treatments, it is imperative for healthcare providers and especially gynecologic oncologists to include a comprehensive evaluation of sexual health as a routine part of the workup of such patients. Although most oncologists are not experienced in treating sexual dysfunctions, simple tools can be incorporated into clinical practice to improve the management of these conditions. Read More

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http://dx.doi.org/10.1136/ijgc-2018-000096DOI Listing
February 2019

Fitz-Hugh-Curtis syndrome.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Department of General Medicine, Chiba University Hospital, Chiba, Japan.

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http://dx.doi.org/10.1136/bcr-2019-229326DOI Listing
February 2019
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Ergometrine-induced atrial fibrillation at caesarean section.

BMJ Case Rep 2019 Feb 13;12(2). Epub 2019 Feb 13.

Department of Obstetrics and Gynaecology, Centenary Hospital for Women and Children, Canberra Hospital, Garran, Australian Capital Territory, Australia.

A 36-year-old woman with a history of one previous caesarean section presented to the birthing suite of a regional hospital with spontaneous rupture of membranes at 39+2/40 weeks. Syntocinon was administered to initiate uterine contractions in the absence of labour, as the patient desired vaginal birth. A caesarean section was subsequently indicated and ergometrine was administered for uterine atony. Read More

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http://dx.doi.org/10.1136/bcr-2018-226747DOI Listing
February 2019

Effect of human embryonic morphological development on fetal growth parameters: the Rotterdam Periconceptional Cohort (Predict Study).

Reprod Biomed Online 2018 Dec 21. Epub 2018 Dec 21.

Department of Obstetrics and Gynaecology, Erasmus MC, University Medical Centre, PO Box 2040, Rotterdam 3000CA, the Netherlands. Electronic address:

Research Question: Is embryonic morphological development according to the Carnegie stages associated with pregnancy outcome?

Design: In a tertiary hospital-based cohort, 182 singleton non-malformed pregnancies were selected. Serial transvaginal three-dimensional ultrasound (3D-US) scans were carried out between 6 and 10 gestational weeks. Embryonic development was annotated according to the morphological criteria of the Carnegie classification using a virtual reality system. Read More

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http://dx.doi.org/10.1016/j.rbmo.2018.12.016DOI Listing
December 2018

Potential of survivin for treatment of gynaecological tumour diseases.

Ceska Gynekol 2018 ;83(3):226-231

Objective: The main purpose of this article is to consolidate known facts about survivin, its contribution to inhibition of apoptosis, impact to tumorigenesis of gynaecological types of tumours. and possibilities of inhibition of survivin on molecular-genetic levels.

Design: A review article. Read More

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January 2018