115,802 results match your criteria Obstetric Anesthesia Digest [Journal]


Atypical case of posterior reversible encephalopathy syndrome related to late onset postpartum eclampsia: A case report.

Medicine (Baltimore) 2019 Apr;98(16):e15187

Advanced Emergency and Critical Care Medical Center, Okayama University Hospital, Okayama City, Okayama, Japan.

Rationale: Eclampsia, an obstetric emergency frequently seen in pregnant or puerperal women, is a risk factor for posterior reversible encephalopathy syndrome (PRES). Most cases of eclampsia occur postpartum. We report a woman with PRES associated with eclampsia 10 weeks post-delivery, the latest onset ever reported. Read More

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http://dx.doi.org/10.1097/MD.0000000000015187DOI Listing

Amniotic Fluid Embolism in a Grown-Up Congenital Heart Disease Patient.

J Cardiovasc Echogr 2019 Jan-Mar;29(1):20-22

Department of Medicine and Surgery, Division of Cardiology, University of Salerno, Largo Città di Ippocrate, Salerno, Italy.

Amniotic fluid embolism (AFE) is a rare but potentially lethal obstetric condition affecting women during labor, delivery, or also in the immediate postpartum period, when amniotic fluid, fetal cells, hair, or other debris could enter the maternal circulation. We present the first case of AFE described in literature in a 33-year-old patient with a complex history of congenital heart disease, where the crucial points for successful course were the prompt recognition and treatment of the disease and the use, for the first time, as diagnostic tool for AFE, of right ventricular free-wall longitudinal speckle-tracking strain. Read More

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http://dx.doi.org/10.4103/jcecho.jcecho_64_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6450229PMC

Fetal movement frequency and the effect of associated perinatal factors: Multicenter study.

Women Birth 2019 Apr 28;32(2):127-130. Epub 2018 Jun 28.

Perinatal Center, Shiga University of Medical Science, Japan.

Background: Decreased fetal movements are associated with adverse perinatal outcomes, including stillbirth. Delayed maternal visits to a health care provider after perceiving decreased fetal movements are frequently observed in stillbirths. Informing pregnant women of the normal range of fetal movement frequency is essential in their earlier visits in order to prevent stillbirth. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18715192183021
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http://dx.doi.org/10.1016/j.wombi.2018.06.010DOI Listing

Fear of childbirth and associated factors among low-risk pregnant women.

J Obstet Gynaecol 2019 Apr 22:1-5. Epub 2019 Apr 22.

a Department of Obstetrics and Gynaecology, Faculty of Medicine Siriraj Hospital , Mahidol University , Bangkok , Thailand.

The aims of this study were to determine prevalence of childbirth fear among uncomplicated pregnant women in Siriraj Hospital and possible associated factors. A total of 305 uncomplicated, singleton pregnant women were enrolled during early third trimester. All participants were interviewed regarding baseline demographic, social, economic, family, and obstetric characteristics. Read More

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https://www.tandfonline.com/doi/full/10.1080/01443615.2019.1
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http://dx.doi.org/10.1080/01443615.2019.1584885DOI Listing
April 2019
1 Read

Influenza and pertussis vaccination of women during pregnancy in Victoria, 2015-2017.

Med J Aust 2019 Apr 21. Epub 2019 Apr 21.

Monash University, Melbourne, VIC.

Objectives: To assess variations by time of year and hospital in the uptake of influenza and pertussis vaccinations by pregnant women in Victoria; to identify factors associated with vaccination uptake.

Design, Setting: Retrospective analysis of data in the Victorian Perinatal Data Collection (VPDC), a population surveillance system for obstetric conditions, procedures, and pregnancy and birth outcomes.

Participants: Women whose pregnancies ended in a live or stillbirth during July 2015 - June 2017. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.5694/mja2.50125
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http://dx.doi.org/10.5694/mja2.50125DOI Listing
April 2019
1 Read

Post-cesarean delivery pain. Management of the opioid-dependent patient before, during and after cesarean delivery.

Authors:
R Landau

Int J Obstet Anesth 2019 Feb 10. Epub 2019 Feb 10.

Virginia Apgar Professor of Anesthesiology, Department of Anesthesiology, Columbia University Medical Center, Columbia University College of Physicians & Surgeons, New York, United States. Electronic address:

The opioid crisis has reached an unprecedented magnitude in the United States and worldwide, and data on opioid use and misuse in the obstetric population are extremely concerning. Despite an abundant number of studies evaluating strategies to prevent neonatal opioid withdrawal syndrome mothers who are chronic opioid users, in babies born to mothers using chronic opioids, numerous questions remain unanswered, including (1) how to optimally manage postpartum pain in opioid-dependent patients (2) how to reconcile buprenorphine and methadone use with intrapartum and postpartum analgesia, so as to avoid opioid withdrawal during and after delivery (3) how to safely and effectively provide a stepwise multimodal approach that incorporates systemic opioid-sparing approaches, such as neuraxial opioids, clonidine, ketamine, gabapentin, and regional anesthetic blocks, to ensure adequate pain relief while avoiding opioid withdrawal (4) how to optimally manage postpartum recovery and (5) how to avoid excessive opioid prescription and possibly left-over opioids that may promote persistent use, misuse and diversion. With the recognition that an increasing number of pregnant women are taking chronic opioids, the goals of this review article are to summarize the existing literature on post-cesarean pain management in the obstetric patient with an opioid-use disorder; and to provide clinicians with a stepwise approach for management before, as well as during and after, cesarean delivery of women who have been chronically using opioids during their pregnancy. Read More

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http://dx.doi.org/10.1016/j.ijoa.2019.01.011DOI Listing
February 2019

Obstetric complications in bipolar disorder: The role of mental health disorders in the risk of caesarean section.

J Affect Disord 2019 Apr 8;252:458-463. Epub 2019 Apr 8.

Perinatal Mental health Unit, Department of Psychiatry and Clinical Psychology, Institute of Neuroscience, Hospital Clinic, IDIBAPS, Barcelona, Catalonia, Spain; Vulnerability, Psychopathology and Gender research group, Generalitat de Catalunya, Catalonia, Spain.

Background: Women with Bipolar Disorder (BD) during pregnancy present a negative impact on them and their babies' health. Caesarean Section (C-Section) is an intervention to reduce complications associated with childbirth, but it also has risks, including maternal infections, anaesthetic and psychological complications. There are few studies that analyse the C-Section rates in women with BD compared to the general population. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01650327183226
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http://dx.doi.org/10.1016/j.jad.2019.04.017DOI Listing
April 2019
2 Reads

Role of Leptin in the Association Between Body Adiposity and Persistent Asthma: A Longitudinal Study.

Obesity (Silver Spring) 2019 Apr 20. Epub 2019 Apr 20.

VIMA: Aging and Chronic Diseases, Epidemiological and Public Health Approaches, INSERM U1168, Villejuif, France.

Objective: Obesity is a likely risk factor for asthma. However, underlying mechanisms by which obesity affects asthma activity remain poorly understood. This study aimed to investigate the role of leptin, an adipocyte-derived proinflammatory protein, as a mediator in the association between body adiposity (assessed using BMI, waist circumference, and body fat percentage) and persistent asthma. Read More

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http://dx.doi.org/10.1002/oby.22466DOI Listing
April 2019
1 Read

Obstetric perineal tears: risk factors, wound infection and dehiscence: a prospective cohort study.

Arch Gynecol Obstet 2019 Apr 19. Epub 2019 Apr 19.

Department of Gynaecology and Obstetrics, Odense University Hospital, J.B. Winsløws Vej 4, 5000, Odense C, Denmark.

Purpose: To assess risk factors for perineal tears, wound infection and dehiscence among primiparous women.

Methods: A prospective cohort study at four Danish hospitals (Odense, Esbjerg, Aarhus and Kolding) among 603 primiparous women sampled in three groups: 203 with none/labia/1st degree, 200 with 2nd degree, and 200 with 3rd/4th degree tears included between July 2015 and January 2018. Baseline data were obtained and a clinical examination of perineal wound healing was performed 11-21 days postpartum. Read More

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http://link.springer.com/10.1007/s00404-019-05165-1
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http://dx.doi.org/10.1007/s00404-019-05165-1DOI Listing
April 2019
5 Reads

What's new in obstetric anesthesia in 2017?

Authors:
A S Habib

Int J Obstet Anesth 2019 Mar 28. Epub 2019 Mar 28.

Department of Anesthesiology, Duke University School of Medicine, Durham, NC, USA. Electronic address:

The Gerard W. Ostheimer lecture is delivered every year at the annual meeting of the Society for Obstetric Anesthesia and Perinatology. The lecture aims to provide the anesthesiologist who provides obstetric anesthesia care with a review of the most relevant articles that were published in the preceding calendar year. Read More

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http://dx.doi.org/10.1016/j.ijoa.2019.03.005DOI Listing
March 2019
2 Reads

Birth ball use for women in labor: A systematic review and meta-analysis.

Complement Ther Clin Pract 2019 May 2;35:92-101. Epub 2019 Feb 2.

Department of Physiotherapy, Universidade Federal de Pernambuco (UFPE), Recife, Pernambuco, Brazil; Post-Graduate Program in Physiotherapy, Universidade Federal de Pernambuco (UFPE), Recife, Pernambuco, Brazil. Electronic address:

Objective: To evaluate, with the best level of evidence, the possible benefits of using birth balls during labor in maternal and neonatal outcomes.

Methods: This research was made using MEDLINE/PubMed, LILCAS, CINAHL, CENTRAL, and SCOPUS databases, with no period or language restrictions. The terms "labor" and "birth ball" were used. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17443881183079
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http://dx.doi.org/10.1016/j.ctcp.2019.01.015DOI Listing
May 2019
4 Reads

Emotional freedom techniques and breathing awareness to reduce childbirth fear: A randomized controlled study.

Complement Ther Clin Pract 2019 May 15;35:224-231. Epub 2019 Feb 15.

Istanbul University-Cerrahpasa, Florence Nightingale Faculty of Nursing, Department of Women Health and Gynecologic Nursing, Abide-i Hürriyet Street, 34381, Şişli, Istanbul, Turkey. Electronic address:

Background: Emotional freedom techniques (EFT) and breathing awareness (BA) are applicable during labour. The present study aimed to determine the effectiveness of EFT and BA in the reduction of childbirth fear.

Materials And Methods: This randomized controlled study included 120 pregnant women, of whom the EFT, BA and control groups. Read More

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http://dx.doi.org/10.1016/j.ctcp.2019.02.011DOI Listing

Use of ultrasound and mHealth to improve perinatal outcomes in low and middle income countries.

Semin Perinatol 2019 Mar 16. Epub 2019 Mar 16.

Department of Obstetrics and Gynecology, Columbia University, New York, NY, USA.

The explosion of mobile health and portable obstetric ultrasound interventions in low- and middle-income countries (LMIC) reflects the optimism that technology can help reduce persistently high rates of maternal and neonatal mortality and morbidity in these settings. While these technology-driven interventions have had success in improving aspects of antenatal and perinatal care, they have not clearly demonstrated reductions in mortality. The expanding synergy between mobile health (mHealth) and ultrasound technology shows promise to enhance care, but it will likely take combining these technological advances with system-wide approaches that also address referral patterns and infrastructure barriers to improve outcomes. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01460005193004
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http://dx.doi.org/10.1053/j.semperi.2019.03.016DOI Listing
March 2019
1 Read

[Perineal risk and obstetrical protection: a survey with birth professionals].

Gynecol Obstet Fertil Senol 2019 Apr 16. Epub 2019 Apr 16.

Pôle de gynécologie-obstétrique, CHRU de Nancy, 10 rue du Docteur Heydenreich, 54 000 Nancy, France; INSERM U1254, CHRU Nancy, Rue du Morvan, 54 000 Vandoeuvre-lès-Nancy, France.

Objectives: The main objective was to evaluate the practices declared by birth professionals in the Lorraine region about perineal obstetric protection (any perineal tear combined). The secondary objective was to evaluate prevention measures performed in practice by birth professionals according to the perineal risk subjectively estimated for each obstetric situation.

Methods: This is a practice survey conducted through an anonymous questionnaire distributed to birth professionals (gynecologists, interns, midwife and midwife student) in October 2016. Read More

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http://dx.doi.org/10.1016/j.gofs.2019.04.012DOI Listing

Shock index thresholds to predict adverse outcomes in maternal hemorrhage and sepsis: a prospective cohort study.

Acta Obstet Gynecol Scand 2019 Apr 18. Epub 2019 Apr 18.

Department of Women and Children's Health, King's College London, London, UK.

Introduction: Shock Index (SI) is a predictor of hemodynamic compromise in obstetric patients. The Shock Index threshold for action is not well understood. We aimed to evaluate Shock Index thresholds as predictors of outcomes in obstetric patients. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/aogs.13626
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http://dx.doi.org/10.1111/aogs.13626DOI Listing
April 2019
1 Read

Women's preferences and factors influencing their obstetric care service utilization in rural Sindh: A Cross sectional Study.

J Pak Med Assoc 2019 Apr;69(4):576-579

Health Services Academy Islamabad.

The objective of this study was to explore women's preferences and factors influencing the obstetric services in a rural setting of Sindh Province. This cross sectional study was conducted on 100 women who were interviewed by using a validated questionnaire. The women who had given birth during the year preceding the study were eligible for inclusion in the study. Read More

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Readability, content, quality and accuracy assessment of internet-based patient education materials relating to labor analgesia.

Int J Obstet Anesth 2019 Jan 8. Epub 2019 Jan 8.

Section of Obstetric Anesthesiology, Department of Anesthesiology, Cedars-Sinai Medical Center, USA.

Background: With over 90% of parturients searching the internet for health information, the quality of information is important. Web-based patient education materials (PEMs) related to labor analgesia are frequently of low readability. This study compares the readability, content, quality and accuracy of labor analgesia-related PEMs from relevant healthcare society websites and the top internet search results. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0959289X183027
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http://dx.doi.org/10.1016/j.ijoa.2019.01.003DOI Listing
January 2019
1 Read

The use of Episcissors-60 to reduce the rate of Obstetric Anal Sphincter Injuries: A systematic review.

Eur J Obstet Gynecol Reprod Biol 2019 Apr 6;237:23-27. Epub 2019 Apr 6.

University Hospital Coventry, Clifford Bridge Road, Coventry, UK.

Objectives: The aim of this systematic review is to evaluate the effect of Episcissors-60, which were designed to improve the accuracy of episiotomies, on the rate of Obstetric Anal Sphincter Injuries.

Study Design: This review is registered with the International Prospective Register of Systematic Reviews (PROSPERO) database (CRD42018094935). A literature search of the PubMed, Embase and Cochrane databases was performed from inception to May 2018. Read More

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http://dx.doi.org/10.1016/j.ejogrb.2019.04.004DOI Listing
April 2019
1.627 Impact Factor

How and why front-line health workers (did not) use a multifaceted mHealth intervention to support maternal and neonatal healthcare decision-making in Ghana.

BMJ Glob Health 2019 8;4(2):e001153. Epub 2019 Mar 8.

Ghana Health Service, Research and Development Division, Dodowa Research Centre, Accra, Ghana.

Introduction: Despite increasing use of mHealth interventions, there remains limited documentation of 'how and why' they are used and therefore the explanatory mechanisms behind observed effects on beneficiary health outcomes. We explored 'how and why' an mHealth intervention to support clinical decision-making by front-line providers of maternal and neonatal healthcare services in a low-resource setting was used. The intervention consisted of phone calls (voice calls), text messaging (short messaging service (SMS)), internet access (data) and access to emergency obstetric and neonatal protocols via an Unstructured Supplementary Service Data (USSD). Read More

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http://gh.bmj.com/lookup/doi/10.1136/bmjgh-2018-001153
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http://dx.doi.org/10.1136/bmjgh-2018-001153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441261PMC
March 2019
1 Read

Latent class analysis of the social determinants of health-seeking behaviour for delivery among pregnant women in Malawi.

BMJ Glob Health 2019 30;4(2):e000930. Epub 2019 Mar 30.

Program in Global Surgery and Social Change, Harvard Medical School, Boston, Massachusetts, USA.

Introduction: In the era of Sustainable Development Goals, reducing maternal and neonatal mortality is a priority. With one of the highest maternal mortality ratios in the world, Malawi has a significant opportunity for improvement. One effort to improve maternal outcomes involves increasing access to high-quality health facilities for delivery. Read More

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http://dx.doi.org/10.1136/bmjgh-2018-000930DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441245PMC

Centers of Excellence for Anesthesia Care of Obstetric Patients.

Anesth Analg 2019 May;128(5):844-846

University of Arkansas for Medical Sciences.

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http://dx.doi.org/10.1213/ANE.0000000000004027DOI Listing

Long-term Breastfeeding in the Prevention of Allergic Rhinitis: Allergic Rhinitis Cohort Study for Kids (ARCO-Kids Study).

Clin Exp Otorhinolaryngol 2019 Apr 18. Epub 2019 Apr 18.

Department of Otorhinolaryngology, Seoul National University College of Medicine, Seoul, Korea.

Objectives: There is a great deal of interest in the possibility that environmental factors may influence the risk of developing allergic rhinitis (AR) in early life. We investigated the simultaneous effects of mode of delivery and duration of breastfeeding on the development of AR in children.

Methods: Data from 1,374 children participating in the Allergic Rhinitis Cohort Study for kids (ARCO-kids study) was analyzed. Read More

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http://dx.doi.org/10.21053/ceo.2018.01781DOI Listing
April 2019
2 Reads

Antigen specific vaccine hesitancy in pregnancy.

Vaccine 2019 Apr 13. Epub 2019 Apr 13.

School of Medicine, Griffith University, Southport, Queensland, Australia. Electronic address:

Background: Vaccinations in pregnancy are recommended for the potential benefits of preventing severe pertussis disease in newborns and for preventing the impact of influenza on the pregnant woman, her foetus in utero and, the newborn in the first six months of life. Published data in Australia suggested that coverage rates were sub-optimal so the reasons for this were reviewed.

Methods: A cross-sectional survey of 1014 postnatal women, aged 18 years and older, who had given birth in the previous six months was undertaken on the Gold Coast in Queensland, Australia. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X193047
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http://dx.doi.org/10.1016/j.vaccine.2019.04.021DOI Listing
April 2019
1 Read

Preference for caesarean attitudes toward birth in a Chilean sample of young adults.

Women Birth 2019 Apr 13. Epub 2019 Apr 13.

Birth Place Lab., University of British Columbia, BC Women's Hospital Shaughnessy Building E418 4500 Oak Street, Vancouver, BC V6H 3N1, Canada. Electronic address:

Background: Little empirical research exists about what motivates birth mode preferences, and even less about this topic in Latin America, where obstetric interventions and caesareans are some of the highest worldwide.

Aim: To identify factors associated with caesarean preference among Chilean men and women who plan to have children and to inform childbirth education and informed consent procedures.

Methods: An online cross-sectional survey measuring attitudes toward birth was administered to graduate students at a large public university in Chile. Read More

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http://dx.doi.org/10.1016/j.wombi.2019.03.012DOI Listing

Obstetric outcomes in women with rheumatoid arthritis: Results from Nationwide Inpatient Sample Database 2003-2011.

Semin Arthritis Rheum 2019 Mar 23. Epub 2019 Mar 23.

University of Mississippi, 2500 North State Street, Jackson, MS 39232, United States.

Objective: Fertility is reduced in patients with Rheumatoid Arthritis due to unknown cause. Few studies have addressed pregnancy outcomes in RA. This study was undertaken to determine the frequency of complications occurring during pregnancy for women with RA and compare with the general obstetric population by using the largest inpatient care database. Read More

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http://dx.doi.org/10.1016/j.semarthrit.2019.03.011DOI Listing
March 2019
1 Read

A gestational vulnerability window for smoking exposure and the increased risk of preterm birth: how timing and intensity of maternal smoking matter.

Reprod Health 2019 Apr 16;16(1):43. Epub 2019 Apr 16.

School of Public Health, Department of Family Science, University of Maryland, 4200 Valley Drive, College Park, MD, 20742, USA.

Background: Reducing the incidence of preterm birth is a national priority. Maternal cigarette smoking is strongly and consistently associated with preterm birth. The objective of this study was to examine prenatal exposure based on combined measures of timing (by trimester) and intensity level (the number of cigarettes smoked per day) of maternal smoking to identify a pregnancy period with the highest risk of preterm birth. Read More

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https://reproductive-health-journal.biomedcentral.com/articl
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http://dx.doi.org/10.1186/s12978-019-0705-xDOI Listing
April 2019
6 Reads

Spatial and temporal trends of cesarean deliveries in Uganda: 2012-2016.

BMC Pregnancy Childbirth 2019 Apr 16;19(1):132. Epub 2019 Apr 16.

African Field Epidemiology Network, Kampala, Uganda.

Background: Cesarean section (CS) is an important intervention in complicated births when the safety of the mother or baby is compromised. Despite worldwide concerns about the overutilization of CS in recent years, many African women and their newborns still die because of limited or no access to CS services. We evaluated temporal and spatial trends in CS births in Uganda and modeled future trends to inform programming. Read More

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https://bmcpregnancychildbirth.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12884-019-2279-6DOI Listing
April 2019
2 Reads

[Assessing post-internship residents’ criteria for their future place of gynecological/obstetric practice in Lorraine].

Sante Publique 2019 November December;30(6):833-843

Objective: Assessing criteria of post-internship choices of residents registered to postgraduate study in gynecology-obstetric (GO) and incentive measures which may impact the attractiveness of maternity hospitals.

Methods: A regional anonymous survey composed of four parts was performed between 2015 and 2016 with 39 residents in GO from Lorraine.

Results: The answer rate was 89. Read More

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http://dx.doi.org/10.3917/spub.187.0833DOI Listing

Risk factors and potential protective factors of pregnancy-induced hypertension in China: A cross-sectional study.

J Clin Hypertens (Greenwich) 2019 Apr 16. Epub 2019 Apr 16.

Department of Obstetrics and Gynecology, Henan Provincial People's Hospital, Henan, China.

A cross-sectional study was conducted to the reported factors and assesses possible protective factors for pregnancy-induced hypertension (PIH) in China. The data of pregnant women who delivered between October 2016 and September 2017 were collected from a birth registry. The primary outcome was the occurrence of PIH. Read More

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http://dx.doi.org/10.1111/jch.13541DOI Listing
April 2019
1 Read

Brucellosis in pregnancy: results of multicenter ID-IRI study.

Eur J Clin Microbiol Infect Dis 2019 Apr 15. Epub 2019 Apr 15.

Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.

Brucellosis in pregnant women is reported to be associated with obstetric complications (OCs), and adequate data for human brucellosis during pregnancy are largely lacking. We performed this multicenter retrospective cross-sectional study to evaluate the epidemiology, clinical course, treatment responses, and outcomes of brucellosis among pregnant women. The study period comprised a 14-year period from January 2002 to December 2015. Read More

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http://link.springer.com/10.1007/s10096-019-03540-z
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http://dx.doi.org/10.1007/s10096-019-03540-zDOI Listing
April 2019
3 Reads

Effect of the drug combination of magnesium sulfate and phentolamine on homocysteine and C-reactive protein in the serum of patients with pregnancy-induced hypertension syndrome.

Exp Ther Med 2019 May 13;17(5):3682-3688. Epub 2019 Mar 13.

Ward 1, Department of Gynecology, Jining No. 1 People's Hospital, Jining, Shandong 272011, P.R. China.

Effect and clinical efficacy of magnesium sulfate combined with phentolamine on homocysteine and C-reactive protein in the serum of patients with pregnancy-induced hypertension syndrome were investigated. A total of 96 patients with pregnancy-induced hypertension syndrome who were diagnosed and treated in Jining No. 1 People's Hospital from February 2016 to January 2018 were retrospectively analyzed. Read More

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http://dx.doi.org/10.3892/etm.2019.7385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447783PMC
May 2019
1 Read

Effects of cooperative blood transfusion and homologous blood transfusion on the production of red blood cell irregular antibodies in obstetric patients.

Exp Ther Med 2019 May 5;17(5):3477-3482. Epub 2019 Mar 5.

Department of Gynecology, Maternity and Child Health Care of Zaozhuang, Zaozhuang, Shandong 277100, P.R. China.

Effects of cooperative blood transfusion and homologous blood transfusion on the production of red blood cell irregular antibodies in obstetric patients were investigated. A total of 300 obstetric patients who underwent blood transfusion in the Maternity and Child Health Care of Zaozhuang from February 2016 to February 2018 were enrolled. There were 150 obstetric patients receiving the same type of transfusion who were included in the control group. Read More

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http://dx.doi.org/10.3892/etm.2019.7343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447778PMC

In vitro comparison of liposomal drug delivery systems targeting the oxytocin receptor: a potential novel treatment for obstetric complications.

Int J Nanomedicine 2019 27;14:2191-2206. Epub 2019 Mar 27.

Centre for Organic Electronics, University of Newcastle, Callaghan, NSW, Australia.

Introduction: Targeted intervention to the uterus has great potential for the treatment of obstetric complications (eg, preterm birth, dysfunctional labor, and postpartum hemorrhage) by improving the effectiveness and safety of therapeutic compounds. In particular, targeting the oxytocin receptor (OTR) is a novel approach for drug delivery to the uterus. The aim of this study was to report the complete data set for the pharmaceutical synthesis and in vitro characterization of PEGylated liposomes conjugated with anti-OTR monoclonal antibodies (OTR-Lipo) or atosiban (ATO-Lipo, OTR antagonist). Read More

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http://dx.doi.org/10.2147/IJN.S198116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443222PMC
March 2019
1 Read

Point-of-care coagulation testing for obstetric hemorrhage: time for a theranostic approach?

Int J Obstet Anesth 2019 Apr 5. Epub 2019 Apr 5.

Brigham and Women's Hospital, Department of Anesthesiology, Perioperative, and Pain Medicine, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ijoa.2019.04.001DOI Listing

Predictors of Obstetric Fistula Repair Outcomes in Lubango, Angola.

J Obstet Gynaecol Can 2019 Apr 12. Epub 2019 Apr 12.

Program in Global Surgery and Social Change, Harvard Medical School, Boston, MA; Center for Surgery and Public Health,(,) Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

Objective: Obstetric fistulas have a significant physical and social impact on many women in Angola. The majority of the population of this sub-Saharan African nation does not have access to high-quality obstetric care, and this is associated with a risk of prolonged labour and formation of obstetric fistulas. Fistulas are challenging to correct surgically and may require repeated operations. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S17012163193008
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http://dx.doi.org/10.1016/j.jogc.2019.01.025DOI Listing
April 2019
6 Reads

CFTR mutation compromises spermatogenesis by enhancing miR-15b maturation and suppressing its regulatory target CDC25A.

Biol Reprod 2019 Apr 15. Epub 2019 Apr 15.

Joint Laboratory of Reproductive Medicine, SCU-CUHK, Key Laboratory of Obstetric, Gynecologic and Pediatric Diseases and Birth Defects of Ministry of Education, West China Second University Hospital, Sichuan University, Chengdu 610041, P.R. China.

MicroRNAs (miRNAs) have recently been shown to be important for spermatogenesis; both DROSHA and Dicer1 KO mice exhibit infertility due to abnormal miRNA expression. However, the roles of individual miRNAs in spermatogenesis remain elusive. Here we demonstrated that miR-15b, a member of the miR-15/16 family, is primarily expressed in testis. Read More

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http://dx.doi.org/10.1093/biolre/ioz062DOI Listing
April 2019
1 Read

Hypertensive Disorders of Pregnancy and Symptoms of Depression and Anxiety as Related to Gestational Age at Birth: Findings from the All Our Families Study.

Psychosom Med 2019 Apr 12. Epub 2019 Apr 12.

Department of Psychology, Faculty of Science, McGill University (Kristin Horsley and Blaine Ditto); Department of Psychology, Faculty of Arts, University of Calgary (Lianne Tomfohr-Madsen); Department of Pediatrics and Community Health Sciences, Cumming School of Medicine (Suzanne Tough).

Objective: To investigate whether symptoms of depression or state anxiety changed the strength or nature of the association between hypertensive disorders of pregnancy (HDP) and gestational age at birth.

Methods: We conducted a secondary analysis of data from the All Our Families Cohort, a prospective pregnancy cohort study based in Calgary, Alberta, Canada. Self-reported depressive symptoms and state anxiety were assessed between three- and five-months' gestation, and obstetrical information including diagnosis of HDP, parity, type of delivery, and gestational age at birth was retrieved from the maternal discharge abstract. Read More

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http://dx.doi.org/10.1097/PSY.0000000000000695DOI Listing

Epidural test dose in obstetric patients: should we still use it?

Curr Opin Anaesthesiol 2019 Apr 9. Epub 2019 Apr 9.

Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany.

Purpose Of Review: As the application of a test dose after epidural catheter insertion in obstetrics has recurrently been associated with serious adverse events affecting both maternal and foetal outcomes, the question whether to test or not remains a controversial issue.

Recent Findings: Present guidelines do not provide clear recommendations in this regard and several recent surveys indicate a heterogeneity in clinical routine.

Summary: Physiological alterations during pregnancy and labour restrict the use and also the validity of traditional test agents. Read More

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http://dx.doi.org/10.1097/ACO.0000000000000721DOI Listing
April 2019
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Anesthetic Considerations of Hereditary Neuropathy With Liability to Pressure Palsies in an Obstetric Patient: A Case Report.

A A Pract 2019 Apr 8. Epub 2019 Apr 8.

The University of Sydney, Sydney, New South Wales, Australia.

Hereditary neuropathy with liability to pressure palsies is an autosomal dominant condition occurring in up to 16 per 100,000 people and predisposes to neural compressive injury. Given the rarity of this condition, no guidelines currently exist for the anesthetic management of hereditary neuropathy with liability to pressure palsies. We describe the management of analgesia during labor in a woman diagnosed with hereditary neuropathy with liability to pressure palsies and a history of nerve palsy after obstetric anesthesia. Read More

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http://dx.doi.org/10.1213/XAA.0000000000001010DOI Listing

Maternal Mortality in Rural Varanasi: Delays, Causes, and Contributing Factors.

Indian J Community Med 2019 Jan-Mar;44(1):26-30

Department of Community Medicine, IMS, BHU, Varanasi, Uttar Pradesh, India.

Background: Pregnancy and motherhood are natural processes and considered to be full of positive experiences. However, for various reasons many women end up dying during pregnancy, childbirth, and the postpartum period. Improving maternal health and reducing maternal mortality have been prioritized in several international declarations and national policies. Read More

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http://dx.doi.org/10.4103/ijcm.IJCM_170_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437805PMC
April 2019
3 Reads

The Spectrum of Adverse Pregnancy Outcomes Based on Kidney Disease Diagnoses: A 20-Year Population Study.

Am J Nephrol 2019 Apr 12;49(5):400-409. Epub 2019 Apr 12.

Central and Northern Adelaide Renal and Transplantation Services (CNARTS), Royal Adelaide Hospital, Adelaide, South Australia, Australia,

Background And Objectives: Kidney disorders in pregnancy may be under-recognized and have variable impact on outcomes depending on diagnosis. Population-level data are limited, particularly for Australia, and comparison of impact of different kidney disorders on pregnancy has rarely been assessed. This study examined the prevalence and outcomes of varied kidney disorders using population-level perinatal data from a large cohort. Read More

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http://dx.doi.org/10.1159/000499965DOI Listing
April 2019
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Quality Improvement Opportunities Identified Through Case Review of Pregnancy-Related Deaths From Obstetric Hemorrhage.

J Obstet Gynecol Neonatal Nurs 2019 Apr 11. Epub 2019 Apr 11.

Objective: To analyze quality improvement opportunities (QIOs) identified through review of cases of maternal death from obstetric hemorrhage by the California Pregnancy-Associated Mortality Review Committee.

Design: Qualitative descriptive using thematic analysis.

Sample: A total of 159 QIOs identified from 33 cases of pregnancy-related deaths from obstetric hemorrhage in California from 2002 to 2007. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S08842175193004
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http://dx.doi.org/10.1016/j.jogn.2019.03.002DOI Listing
April 2019
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Translating Maternal Mortality Review Into Quality Improvement Opportunities in Response to Pregnancy-Related Deaths in California.

J Obstet Gynecol Neonatal Nurs 2019 Apr 11. Epub 2019 Apr 11.

Objective: To describe quality improvement opportunities (QIOs) associated with the five leading causes of pregnancy-related death in California and the methods by which the QIOs were collected by the California Pregnancy-Associated Mortality Review committee.

Design: Qualitative, descriptive design using thematic analysis.

Sample: A total of 907 QIOs identified from 203 cases of pregnancy-related deaths from cardiovascular disease, preeclampsia/eclampsia, hemorrhage, venous thromboembolism, and sepsis that occurred in California from 2002 to 2007. Read More

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http://dx.doi.org/10.1016/j.jogn.2019.03.003DOI Listing
April 2019
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Comparing the diagnostic accuracy of three ultrasound modalities for diagnosing obstetric anal sphincter injuries.

Am J Obstet Gynecol 2019 Apr 11. Epub 2019 Apr 11.

Obstetrics and Gynecology, Croydon University Hospital, London, United Kingdom. Electronic address:

Background: The optimal imaging modality of obstetric anal sphincter injuries (OASIs) needs to take into consideration convenience, availability and ability to assess the sphincter morphology. Endoanal ultrasound is currently regarded as the reference standard but is not widely available in obstetric units. Exoanal alternatives exist, such as three-dimensional (3D) introital or transperineal ultrasound, which are already readily available in most obstetrics and gynecology units. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.04.009DOI Listing

Spontaneous preterm labour that leads to preterm birth: An update and personal reflection.

Authors:
Ronald F Lamont

Placenta 2019 Mar 25. Epub 2019 Mar 25.

Department of Gynaecology and Obstetrics, University of Southern Denmark, Odense University Hospital, Odense, Denmark, and Division of Surgery, University College London, Northwick Park Institute for Medical Research Campus, London, UK. Electronic address:

Objective: The objective was to provide an update of progress made over time (including personal reflection) of our attempts to reduce the mortality and morbidity associated with spontaneous preterm labour that leads to preterm birth.

Methods: An experienced and evidence based approach was taken to provide an overview of progress made over a generation (∼40 years) in our understanding of spontaneous preterm labour.

Results: It is evident that we have made significant progress in our understanding of the aetiology, the measurement of the burden, the basic science, systems biology and mechanical pathways of the preterm parturition syndrome. Read More

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http://dx.doi.org/10.1016/j.placenta.2019.03.010DOI Listing

Fetal electrocardiography ST analysis for intrapartum monitoring: a critical appraisal of conflicting evidence and a way forward.

Am J Obstet Gynecol 2019 Apr 10. Epub 2019 Apr 10.

In the past century, some areas of obstetric including intrapartum care have been slow to benefit from the dramatic advances in technology and medical care. Although fetal heart rate monitoring (cardiotocography, CTG) became available a half century ago, its interpretation often differs between institutions and countries, its diagnostic accuracy needs improvement, and a technology to help reduce the unnecessary obstetric interventions that have accompanied the CTG is urgently needed. During the second half of the 20 century, key findings in animal experiments captured the close relationship between myocardial glycogenolysis, myocardial workload, and ST changes, thus demonstrating that ST waveform analysis of the fetal ECG can provide information on oxygenation of the fetal myocardium and establishing the physiological basis for the use of ECG in intrapartum fetal surveillance. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.04.003DOI Listing
April 2019
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Quality Improvement Opportunities Identified Through Case Review of Pregnancy-Related Deaths From Preeclampsia/Eclampsia.

J Obstet Gynecol Neonatal Nurs 2019 Apr 10. Epub 2019 Apr 10.

Objective: To analyze quality improvement opportunities (QIOs) identified through review of cases of maternal death from preeclampsia/eclampsia by the California Pregnancy-Associated Mortality Review Committee.

Design: Qualitative descriptive design using thematic analysis.

Sample: A total of 242 QIOs identified from 54 cases of pregnancy-related deaths from preeclampsia/eclampsia in California between 2002 and 2007. Read More

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http://dx.doi.org/10.1016/j.jogn.2019.02.008DOI Listing
April 2019
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[Gestational diabetes mellitus (Update 2019)].

Wien Klin Wochenschr 2019 Apr 12. Epub 2019 Apr 12.

Abteilung für Innere Medizin, Privatklinik Wehrle-Diakonissen, Salzburg, Österreich.

Gestational diabetes mellitus (GDM) is defined as a glucose tolerance disorder with onset during pregnancy and is associated with increased feto-maternal morbidity as well as long-term complications in mother and child. Women who fulfil the criteria of a manifest diabetes in early pregnancy (fasting plasma glucose >126 mg/dl, spontaneous glucose level >200 mg/dl or HbA1c > 6.5% before 20 weeks of gestation) should be classified as having manifest diabetes in pregnancy and treated as such. Read More

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http://dx.doi.org/10.1007/s00508-018-1419-8DOI Listing
April 2019
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Difficult case: rituximab in anti-SRP antibody myositis in pregnancy.

Pract Neurol 2019 Apr 12. Epub 2019 Apr 12.

Imperial College Healthcare NHS Trust, London, UK

A 30-year-old nulliparous woman presented at 15-week gestation with severe skeletal and respiratory muscle weakness, having been diagnosed with anti-signal recognition particle antibody myositis 3 years before. Remission had previously been induced with rituximab (after failure of standard therapies). She had continued oral prednisolone and rituximab every 6 months but had stopped this when planning pregnancy. Read More

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http://dx.doi.org/10.1136/practneurol-2018-002168DOI Listing
April 2019
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