301,474 results match your criteria Obesity Silver Spring Md.[Journal]


[Correlation among serum levels of Irisin, insulin resistance and abdominal obesityin patients with first-episode schizophrenia].

Zhonghua Yi Xue Za Zhi 2019 Feb;99(7):520-524

Department of Psychiatry, First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, China.

To explore the possible role of Irisin in antipsychotic drug-induced insulin resistance and abdominal obesity in patients with schizophrenia and to provide a theoretical basis for the prevention of antipsychotic drug-induced obesity. Fifty-five patients with first-episode schizophrenia, from the First Affiliated Hospital of Zhengzhou University, between January 2016 and December 2017, were admitted as well as fifty healthy controls during the same period. Serum Irisin levels were measured by enzyme-linked immunosorbent assay (ELISA). Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2019.07.009DOI Listing
February 2019

Sexual orientation identity in relation to unhealthy body mass index: individual participant data meta-analysis of 93 429 individuals from 12 UK health surveys.

J Public Health (Oxf) 2019 Feb 21. Epub 2019 Feb 21.

Public Health England, London, UK.

Background: Lesbian, gay and bisexual adults are more likely than heterosexual adults to experience worse health outcomes. Despite increasing public health interest in the importance of maintaining a healthy body weight, no study has considered sexual orientation identity (SOI) and unhealthy BMI categories among adults in the UK population.

Methods: Individual participant data meta-analysis using pooled data from population health surveys reporting on 93 429 adults with data on SOI, BMI and study covariates. Read More

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http://dx.doi.org/10.1093/pubmed/fdy224DOI Listing
February 2019

Obesity and Laboratory Aspirin Resistance in High Risk Pregnant Women Treated with Low Dose Aspirin.

Am J Obstet Gynecol 2019 Jan 29. Epub 2019 Jan 29.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, The Ohio State University College of Medicine, Columbus, OH.

Background: Low dose aspirin (LDA) is used for preeclampsia (PE) prevention in high risk women, but the precise mechanism and optimal dose is unknown. Evidence suggests that an imbalance in prostacyclin and thromboxane A (TXA) plays a key role in the pathogenesis of PE. Aspirin has a dose-dependent effect blocking production of TXA, a potent stimulator of platelet aggregation and promoter of vasoconstriction. Read More

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http://dx.doi.org/10.1016/j.ajog.2019.01.222DOI Listing
January 2019

Cholinergic drugs ameliorate endothelial dysfunction by decreasing O-GlcNAcylation via M3 AChR-AMPK-ER stress signaling.

Life Sci 2019 Feb 17. Epub 2019 Feb 17.

Department of Pharmacology, School of Basic Medical Sciences, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi 710061, People's Republic of China. Electronic address:

Aims: Obesity is associated with increased cardiovascular morbidity and mortality. It is accompanied by augmented O-linked β-N-acetylglucosamine (O-GlcNAc) modification of proteins via increasing hexosamine biosynthetic pathway (HBP) flux. However, the changes and regulation of the O-GlcNAc levels induced by obesity are unclear. Read More

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http://dx.doi.org/10.1016/j.lfs.2019.02.036DOI Listing
February 2019

Impact of maternal body mass index and gestational weight gain on pregnancy complications: An individual participant data meta-analysis of European, North American and Australian cohorts.

BJOG 2019 Feb 20. Epub 2019 Feb 20.

The Generation R Study Group, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.

Objective: To assess the separate and combined associations of maternal pre-pregnancy BMI and gestational weight gain with the risks of pregnancy complications and their population impact.

Design: Individual participant data meta-analysis of 39 cohorts.

Setting: Europe, North America and Oceania. Read More

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http://dx.doi.org/10.1111/1471-0528.15661DOI Listing
February 2019

Gender differences in lifestyle and risk factors of metabolic syndrome: Do women have better health habits than men?

J Clin Nurs 2019 Feb 20. Epub 2019 Feb 20.

Department of Nursing, Chang Gung University of Science and Technology, No.261, Wenhua 1st Rd., Guishan Dist. 33303, Taoyuan City, Taiwan.

Aims And Objectives: The purpose of this paper was to examine the gender-specific lifestyles of adults with metabolic syndrome in the Taiwanese community.

Background: Many studies show different prevalence of metabolic syndrome in males and females, however few studies have investigated gender-specific lifestyle risk factors, which are important for effectively reducing prevalence.

Design: A cross-sectional study design was used. Read More

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http://dx.doi.org/10.1111/jocn.14824DOI Listing
February 2019

Association of vaspin rs2236242 gene variants with type 2 diabetes and obesity in a Chinese population: A prospective, single-center study.

J Cell Physiol 2019 Feb 20. Epub 2019 Feb 20.

Department of Nephrology, Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University, Shanghai, People's Republic of China.

Aim: Vaspin is an adipokine separated from visceral fat tissues of obese diabetic rats. This study was to investigate the association between vaspin rs2236242 gene polymorphism and type 2 diabetes mellitus (T2DM) or obesity in a Chinese population.

Materials And Methods: T2DM patients and nondiabetic controls were recruited from Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University (Shanghai, China) from May 1, 2015 to June 30, 2017. Read More

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http://dx.doi.org/10.1002/jcp.28267DOI Listing
February 2019

Association of cardiovascular autonomic dysfunction with peripheral arterial stiffness in patients with type 1 diabetes.

J Clin Endocrinol Metab 2019 Feb 20. Epub 2019 Feb 20.

Department of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, Madrid, Spain.

Context: Cardiovascular autonomic (CAN) neuropathy appears to contribute to peripheral arterial stiffness (AS) in type 1 diabetes. If CAN in patients with AS is associated to concomitant asymptomatic atherosclerotic disease (aPAD) remains unclear.

Objective: To assess the risk of CAN in patients with type 1 diabetes and AS and its potential association to atherosclerosis. Read More

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http://dx.doi.org/10.1210/jc.2018-02729DOI Listing
February 2019

A pilot study of metabolic fitness effects of weight-supported walking in women with obesity.

PLoS One 2019 20;14(2):e0211529. Epub 2019 Feb 20.

Department of Surgery, SUNY Downstate Medical Center, Brooklyn, New York, United States of America.

Background: This is an exploratory pilot study of novel technology enabling people with mobility disability to walk with minimal effort, in the "sedentary range". The study's premise is that impairment of the leading physical activity of daily living, walking, is a major contributor to a dysmetabolic state driving many prevalent "civilization diseases" associated with insulin resistance.

Methods: We explore within-subject changes in standard oral glucose tolerance (OGT) tests including metabotropic molecules after 22 twice-weekly, 30-minute bouts of weight-supported light-moderate physical activity in 16 non-diabetic obese, otherwise healthy, reproductive-age, volunteer women walking on an "anti-gravity" lower-body positive pressure (LBPP) treadmill. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0211529PLOS
February 2019

Limited significance of repeated long-term radiological and hormonal examination in nonfunctioning adrenal incidentalomas.

Int Braz J Urol 2018 Dec 18;44. Epub 2018 Dec 18.

Division of Urology, Department of Regenerative and Transplant Medicine, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.

Purpose: The purposes of the present study were to evaluate growth rate of nonfunctioning adrenal incidentalomas (AIs) and their development to hormonal hypersecretion on follow-up.

Materials And Methods: A retrospective study was conducted from the electronic medical records. A total of 314 patients were diagnosed with adrenal tumors between 2000 and 2016. Read More

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http://dx.doi.org/10.1590/S1677-5538.IBJU.2018.0235DOI Listing
December 2018

[Formation in the phylogenesis of three pulls of cells with expressed different absorption and metabolism of fatty acids. Insulin and medium chains fatty acids.]

Klin Lab Diagn 2018 ;63(12):732-740

Moscow State University M.V. Lomonosov, 119991, Moscow.

Somatic cells at the early stages of phylogenesis realized the metabolism of long-chain fatty acids (FA), primarily palmitic saturated FA. It dominated the construction of a bilayer cell membrane and as a substrate for oxidation in mitochondria during energy production. Later, polyene FAs became involved in the construction of the cell membrane, the membranes of intracellular organelles, and became the substrate for the synthesis of biologically active eicosanoids. Read More

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http://dx.doi.org/10.18821/0869-2084-2018-63-12-732-740DOI Listing
January 2018

The role of maternal obesity in infant outcomes in polycystic ovary syndrome-A systematic review, meta-analysis, and meta-regression.

Obes Rev 2019 Feb 20. Epub 2019 Feb 20.

Monash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.

Polycystic ovary syndrome (PCOS) is associated with worsened pregnancy and infant outcomes, higher body mass index (BMI), and longitudinal weight gain. Despite most of the clinical features of PCOS being risk factors for worsened infant outcomes in the general population, their impact on infant outcomes in PCOS is unknown. We aimed to investigate the association of PCOS with infant outcomes considering maternal adiposity, other known risk factors, and potential confounders. Read More

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http://dx.doi.org/10.1111/obr.12832DOI Listing
February 2019

Risk factors for hypertension in Canada.

Health Rep 2019 Feb;30(2):3-13

Health Analysis Division, Statistics Canada, Ottawa Hospital Research Institute, and the Institute of Clinical and Evaluative Sciences, Ottawa, Ontario.

Background: Hypertension (or high blood pressure) affects almost one in four adults in Canada. Quantifying risk factors associated with hypertension may help to inform prevention efforts.

Data And Methods: Data from the first four cycles of the Canadian Health Measures Survey (including 13,407 respondents) were used to identify hypertension status by systolic and diastolic blood pressure levels and the use of antihypertensive medications. Read More

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February 2019

Changes in Sexual Functioning in Women and Men in the 5 Years After Bariatric Surgery.

JAMA Surg 2019 Feb 20. Epub 2019 Feb 20.

University of California, San Francisco.

Importance: Short-term improvements in sexual functioning are reported after bariatric surgery, but to our knowledge, little is known about the durability of these improvements.

Objective: To determine the percentage of adults with impairment in sexual functioning who experience durable improvements in sexual functioning after bariatric surgery and to identify factors associated with improvements.

Design, Setting, And Participants: The Longitudinal Assessment of Bariatric Surgery-2 is an observational cohort study conducted at 10 hospitals in 6 US clinical centers. Read More

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http://dx.doi.org/10.1001/jamasurg.2018.1162DOI Listing
February 2019

Clinical Features and Comorbidities of Patients With Necrobiosis Lipoidica With or Without Diabetes.

JAMA Dermatol 2019 Feb 20. Epub 2019 Feb 20.

Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia.

Importance: Necrobiosis lipoidica (NL) is a rare granulomatous condition. Current knowledge of its key features is based on a limited number of studies and case reports, leading to wide variability in the characterization of its defining features, with limited comparison of patients with or without diabetes.

Objective: To evaluate the epidemiologic characteristics, clinical features, and disease associations of NL in patients with or without type 1 or 2 diabetes. Read More

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http://dx.doi.org/10.1001/jamadermatol.2018.5635DOI Listing
February 2019

Autonomic responses induced by aerobic submaximal exercise in obese and overweight adolescents.

Cardiol Young 2019 Feb;29(2):169-173

3Post-Graduate Program in Physical Therapy,UNESP,Presidente Prudente,SP,Brazil.

Background: Graded exercises tests are performed in adult populations; nonetheless, the use of this type of assessment is greatly understudied in overweight and obese adolescents.

Objective: To investigate heart rate autonomic responses to submaximal aerobic exercise in obese and overweight adolescents.

Methods: We recruited 40 adolescents divided into two groups: (1) overweight group comprising 10 boys and 10 girls between Z-score +1 and +2 and (2) obese group comprising 10 boys and 10 girls above Z-score >+2. Read More

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http://dx.doi.org/10.1017/S1047951118002007DOI Listing
February 2019

Risk factors for development of obesity in an ethnically diverse CHD population.

Cardiol Young 2019 Feb;29(2):123-127

2Department of Pediatrics,Icahn School of Medicine at Mount Sinai,New York,NY,USA.

Objectives: Previous cross-sectional studies have demonstrated obesity rates in children with CHD and the general paediatric population. We reviewed longitudinal data to identify factors predisposing to the development of obesity in children, hypothesising that age may be an important risk factor for body mass index growth.Study designRetrospective electronic health records were reviewed in all 5-20-year-old CHD patients seen between 2011 and 2015, and in age-, sex-, and race/ethnicity-matched controls. Read More

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http://dx.doi.org/10.1017/S1047951118001889DOI Listing
February 2019

Activating Effects of Phenolics from Apache Red Zea mays L. on Free Fatty-Acid Receptor-1 and Glucokinase Evaluated with a Dual Culture System with Epithelial, Pancreatic and Liver Cells.

J Agric Food Chem 2019 Feb 20. Epub 2019 Feb 20.

The aim was to characterize a phenolic-rich water extract from the pericarp of an improved genotype of Apache red maize (RPE), and evaluate its ability to activate the type-2 diabetes markers free fatty acid receptor 1 (GPR40) and glucokinase (GK) in vitro. The extract contained mainly phenolic acids, anthocyanins, and other flavonoids. RPE inhibited α-amylase (IC50 = 88. Read More

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http://dx.doi.org/10.1021/acs.jafc.8b06642DOI Listing
February 2019

Physicochemical properties, sensory traits and storage stability of reduced-fat frankfurters formulated by replacing beef tallow with defatted bovine heart.

Meat Sci 2019 Jan 30;151:89-97. Epub 2019 Jan 30.

Division of Applied Life Science (BK21 Plus), Gyeongsang National University, Jinju 52828, Republic of Korea; Institute of Agriculture and Life Sciences, Gyeongsang National University, Jinju 52828, Republic of Korea. Electronic address:

The consumer interests for low-fat meat products are increasing to reduce obesity and chronic diseases. Reduced-fat frankfurter (RFF) was prepared by replacing beef tallow with defatted bovine heart (DBH) produced by supercritical-CO (SC-CO) and hexane. Six different frankfurters i. Read More

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http://dx.doi.org/10.1016/j.meatsci.2019.01.011DOI Listing
January 2019

The impact of BMI on operating room time, blood loss, and hospital stay in patients undergoing spinal fusion.

Clin Neurol Neurosurg 2019 Feb 11;179:19-22. Epub 2019 Feb 11.

Boulder Neurosurgical Associates, Boulder, CO, United States; Justin Parker Neurological Institute, Boulder, CO, United States. Electronic address:

Objective: Obesity affects not only the health of an individual but society as a whole and especially the healthcare system. Healthcare providers are faced with challenges to deliver adequate care in this resource-limited environment, assure safety, and accommodate the increasing population of overweight patients. The effects of increased body mass index (BMI) on clinical outcomes, complications, health care resource utilization, effectiveness of minimally invasive approaches, and perioperative parameters in spine surgeries have all been previously studied, but the majority of these findings are conflicting rather than conclusive. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03038467193003
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http://dx.doi.org/10.1016/j.clineuro.2019.02.012DOI Listing
February 2019
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Effects of myofascial release in erector spinae myoelectric activity and lumbar spine kinematics in non-specific chronic low back pain: Randomized controlled trial.

Clin Biomech (Bristol, Avon) 2019 Feb 14;63:27-33. Epub 2019 Feb 14.

Department of Anatomy and Human Embryology, Universitat de València, Valencia, Spain.

Background: Flexion-relaxation response of the lumbar erector spinae has been previously studied after different interventions such as exercise programs or spinal manipulation, in subjects with chronic low back pain. The objective of the study was to investigate the effects of an isolated myofascial release protocol on erector spinae myoelectric activity and lumbar spine kinematics in chronic low back pain.

Methods: Thirty-six participants, with nonspecific chronic low back pain, were randomized to myofascial release group (n = 18) receiving four sessions of myofascial treatment, each lasting 40 min, and to control group (n = 18) receiving a sham myofascial release. Read More

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http://dx.doi.org/10.1016/j.clinbiomech.2019.02.009DOI Listing
February 2019

Uncovering genetic mechanisms of kidney aging through transcriptomics, genomics, and epigenomics.

Kidney Int 2019 Mar;95(3):624-635

Division of Cardiovascular Sciences, School of Medical Sciences, Faculty of Medicine, Biology and Health, University of Manchester, Manchester, UK; Division of Medicine and Manchester Heart Centre, Manchester University National Health Service Foundation Trust, Manchester Academic Health Science Centre, Manchester, UK. Electronic address:

Nephrons scar and involute during aging, increasing the risk of chronic kidney disease. Little is known, however, about genetic mechanisms of kidney aging. We sought to define the signatures of age on the renal transcriptome using 563 human kidneys. Read More

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http://dx.doi.org/10.1016/j.kint.2018.10.029DOI Listing

Renal biopsy findings in patients with extreme obesity: more heterogeneous than you think.

Kidney Int 2019 Mar;95(3):495-498

Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USA.

The number of obese and morbidly obese patients is increasing and so is the burden of renal disease in these patients. In a large series of biopsies from the morbidly obese patient population, Choung et al. show that there is heterogeneity in the renal disease affecting this population. Read More

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http://dx.doi.org/10.1016/j.kint.2018.12.008DOI Listing

Analysis of the efficacy of an internet-based self-administered intervention ("Living Better") to promote healthy habits in a population with obesity and hypertension: An exploratory randomized controlled trial.

Int J Med Inform 2019 Apr 21;124:13-23. Epub 2018 Dec 21.

Universitat de València, Facultad de Psicología, Valencia, Spain; CIBER Fisiopatología Obesidad y Nutrición (CB06/03), Instituto Carlos III, Spain. Electronic address:

Introduction: Changes in unhealthy lifestyles are key elements in the prevention and treatment of obesity and hypertension. Internet-based programs offer great potential for the implementation of evidence-based interventions focused on promoting healthy habits. We evaluate the efficacy of an Internet-based self-administered program ("Living Better") that addresses people diagnosed as being overweight or having type I obesity and hypertension. Read More

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http://dx.doi.org/10.1016/j.ijmedinf.2018.12.007DOI Listing

Dietary intake of people with severe mental illness: systematic review and meta-analysis.

Br J Psychiatry 2019 Feb 20:1-9. Epub 2019 Feb 20.

Associate Professor in Nutrition and Dietetics,School of Health Sciences and Priority Research Centre for Physical Activity and Nutrition,University of Newcastle,Australia.

Background: Severe mental illness (SMI) is thought to be associated with lower diet quality and adverse eating behaviours contributing towards physical health disparities. A rigorous review of the studies looking at dietary intake in psychotic disorders and bipolar disorder is lacking.AimsTo conduct a systematic, comprehensive evaluation of the published research on dietary intake in psychotic disorders and bipolar disorder. Read More

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http://dx.doi.org/10.1192/bjp.2019.20DOI Listing
February 2019

Perceived benefits and barriers of walking among overweight and obese adults.

Health Mark Q 2019 Feb 20:1-17. Epub 2019 Feb 20.

a Department of Marketing , Griffith University , Nathan , Queensland , Australia.

The current study aimed to explore perceived barriers and benefits of walking of overweight and obese adults. Fifteen face-to-face, semistructured interviews were conducted. Content and thematic analyses were used. Read More

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http://dx.doi.org/10.1080/07359683.2019.1567004DOI Listing
February 2019

The association of type D personality and depression with infertility in women.

J Psychosom Obstet Gynaecol 2019 Feb 20:1-8. Epub 2019 Feb 20.

a Department of Obstetrics and Gynecology , In vitro Fertilization Unit, Suleyman Demirel University Faculty of Medicine , Isparta , Turkey.

Purpose: Type D personality-defined as the presence of two personality characters, namely negative affectivity (NA) and social inhibition (SI)-is associated with various disorders. The 14-item Type D Scale (DS14), which consists of NA and SI subscales, can be used for the detection of the presence of Type D personality. The aim of our study was to investigate the association of Type D personality and depression with infertility in women. Read More

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http://dx.doi.org/10.1080/0167482X.2019.1573224DOI Listing
February 2019

Melanocortin 3 receptor gene polymorphism is associated with polycystic ovary syndrome in Turkish population.

Gynecol Endocrinol 2019 Feb 20:1-6. Epub 2019 Feb 20.

h Department of Pharmacology , Sivas Numune Hospital , Sivas , Turkey.

Polycystic ovary syndrome (PCOS) is a frequent complex disorder with an ill-defined etiology. Genetic factors seem rather effective at the occurrence of the disease, however, the evidence of established various studies results are unsatisfied. We aimed to make a contribution to the genetic baseline of the disease by investigating melanocortin 3 receptor gene polymorphism in affected patients. Read More

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http://dx.doi.org/10.1080/09513590.2019.1576614DOI Listing
February 2019

Relative sarcopenia and mortality and the modifying effects of chronic kidney disease and adiposity.

J Cachexia Sarcopenia Muscle 2019 Feb 19. Epub 2019 Feb 19.

Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.

Background: Conventional definitions of sarcopenia based on lean mass may fail to capture low lean mass relative to higher fat mass, that is, relative sarcopenia. The objective of this study is to determine the associations of sarcopenia and relative sarcopenia with mortality independent of co-morbidities, and whether chronic kidney disease (CKD) and adiposity alter these associations.

Methods: Dual energy X-ray absorptiometry-derived appendicular lean mass index (ALMI, kg/m ) and fat mass index (FMI, kg/m ) were assessed in 14 850 National Health and Nutrition Examination Survey participants from 1999 to 2006 and were linked to death certificate data in the National Death Index with follow-up through 2011. Read More

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http://dx.doi.org/10.1002/jcsm.12396DOI Listing
February 2019

Evaluation of a rare glucose-dependent insulinotropic polypeptide receptor variant in a patient with diabetes.

Diabetes Obes Metab 2019 Feb 19. Epub 2019 Feb 19.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany; Institute of Experimental Pediatric Endocrinology, Berlin, Germany.

Aims: Glucose-dependent insulinotropic polypeptide (GIP) is an incretin hormone that augments insulin secretion in pancreatic β-cells via its glucose-dependent insulinotropic polypeptide receptor (GIPR). Recent genome-wide association studies identified a single nucleotide variant (SNV) in the GIPR encoding gene (GIPR), rs1800437, that is associated with obesity and insulin resistance. In the present study, we tested whether GIPR variants contribute to obesity and disturb glucose homeostasis or diabetes in specific patient populations. Read More

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http://dx.doi.org/10.1111/dom.13634DOI Listing
February 2019

Umbilical Single-Port Sleeve Gastrectomy as a Standardized Procedure: How to Do It? (Video).

Obes Surg 2019 Feb 19. Epub 2019 Feb 19.

Department of Digestive Diseases, Obesity center, Institut Mutualiste Montsouris, Paris Descartes University, Paris, France.

Background: Laparoscopic sleeve gastrectomy is the most common bariatric procedure worldwide, commonly performed using laparoscopic multiport. Feasibility and safety of single-port sleeve gastrectomy (SPSG) have been proved. We reported a standardized procedure describing the different steps as a reference for bariatric surgeons. Read More

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http://dx.doi.org/10.1007/s11695-019-03728-4DOI Listing
February 2019

Exercise physiology: future opportunities and challenges.

Pflugers Arch 2019 Feb 19. Epub 2019 Feb 19.

Section for Cell Biology and Physiology, Department of Biology, University of Copenhagen, Universitetsparken 13, 2100, Copenhagen Ø, Denmark.

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http://dx.doi.org/10.1007/s00424-019-02263-6DOI Listing
February 2019

A systematic review of tailored eHealth interventions for weight loss.

Digit Health 2019 Jan-Dec;5:2055207619826685. Epub 2019 Feb 5.

School of Applied Psychology, University College Cork, Ireland.

Objective: The aim of this study is to review the evidence for tailored eHealth weight-loss interventions, describing in detail: 1. how tailoring was implemented in these studies and 2. whether these tailored approaches were effective in producing weight loss compared with generic or inactive controls. Read More

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http://dx.doi.org/10.1177/2055207619826685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366004PMC
February 2019

Miniature Schnauzers under primary veterinary care in the UK in 2013: demography, mortality and disorders.

Canine Genet Epidemiol 2019 15;6. Epub 2019 Feb 15.

Bath Veterinary Referrals, Rosemary Lodge, Wellsway, Bath, BA2 5RL UK.

Background: Individual dog breeds are often reported as predisposed to specific breed-related disorders but reliable epidemiological data on disease prevalence are sparse. The Miniature Schnauzer in the UK is a popular small breed dog that is often considered as relatively healthy and long-lived, but is this really true? This study aimed to use data from the VetCompass™ Programme at the Royal Veterinary College to characterise the demography, mortality and common disorders of the general population of Miniature Schnauzers under veterinary care in the UK.

Results: The study population of 455,557 dogs from 304 clinics in the VetCompass™ database under veterinary care during 2013 included 3857 Miniature Schnauzers (0. Read More

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http://dx.doi.org/10.1186/s40575-019-0069-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6376765PMC
February 2019

Expression of Hcy and blood lipid levels in serum of CHD patients and analysis of risk factors for CHD.

Exp Ther Med 2019 Mar 18;17(3):1756-1760. Epub 2018 Dec 18.

Department of Emergency, Weifang People's Hospital, Weifang, Shandong 261000, P.R. China.

Expression of homocysteine (Hcy) and blood lipid levels in serum of atherosclerotic coronary heart disease (CHD) patients was investigated and the related risk factors were analyzed. A total of 148 CHD patients were selected as study group and another 120 healthy people attending Weifang People's Hospital for physical examination in the same period as control group. Hcy and blood lipid levels in serum were measured in the two groups, including total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C). Read More

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http://dx.doi.org/10.3892/etm.2018.7111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364198PMC

Lifestyle Medicine: The Health Promoting Power of Daily Habits and Practices.

Authors:
James M Rippe

Am J Lifestyle Med 2018 Nov-Dec;12(6):499-512. Epub 2018 Jul 20.

Rippe Lifestyle Institute, Shrewsbury, Massachusetts.

There is no longer any serious doubt that daily habits and actions profoundly affect both short-term and long-term health and quality of life. This concept is supported by literally thousands of research articles and incorporated in multiple evidence-based guidelines for the prevention and/or treatment of chronic metabolic diseases. The study of how habits and actions affect both prevention and treatment of diseases has coalesced around the concept of "lifestyle medicine. Read More

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http://dx.doi.org/10.1177/1559827618785554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367881PMC

Health and Wellness Coaching Improves Weight and Nutrition Behaviors.

Authors:
Julie Kennel

Am J Lifestyle Med 2018 Nov-Dec;12(6):448-450. Epub 2018 Aug 9.

Ohio State University, Columbus, Ohio.

Most Americans have an eating pattern inconsistent with the Dietary Guidelines, putting them at risk for obesity and chronic disease. Health and wellness coaching (HWC) for lifestyle behavior change is emerging as a potentially effective tool to prevent and treat chronic disease. A systematic literature review identified 11 randomized controlled trials studying the use of HWC for improving nutrition-related biomarkers and eating behaviors. Read More

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http://dx.doi.org/10.1177/1559827618792846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367877PMC

Body-mass index correlates with severity and mortality in acute pancreatitis: A meta-analysis.

World J Gastroenterol 2019 Feb;25(6):729-743

Institute for Translational Medicine, Medical School, University of Pécs, Pécs 7624, Hungary.

Background: Obesity rates have increased sharply in recent decades. As there is a growing number of cases in which acute pancreatitis (AP) is accompanied by obesity, we found it clinically relevant to investigate how body-mass index (BMI) affects the outcome of the disease.

Aim: To quantify the association between subgroups of BMI and the severity and mortality of AP. Read More

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http://dx.doi.org/10.3748/wjg.v25.i6.729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378543PMC
February 2019

Effect of Sheng-jiang powder on multiple-organ inflammatory injury in acute pancreatitis in rats fed a high-fat diet.

World J Gastroenterol 2019 Feb;25(6):683-695

Department of Integrative Medicine, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.

Background: Obesity worsens inflammatory organ injury in acute pancreatitis (AP), but there is no effective preventive strategy. Sheng-jiang powder (SJP) has been shown to alleviate multiple-organ inflammatory injury in rats with high-fat diet-induced obesity. Hence, SJP is supposed to have an effect on multiple-organ inflammatory injury in AP in rats fed a high-fat diet. Read More

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http://dx.doi.org/10.3748/wjg.v25.i6.683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378539PMC
February 2019

Performing the screw fixation from C3 to odontoid process in a patient with Klippel-Feil syndrome and type II odontoid fracture.

J Craniovertebr Junction Spine 2018 Oct-Dec;9(4):277-279

Department of Neurosurgery, Faculty of Medicine, Kirikkale University, Kirikkale, Turkey.

A 56-year-old female patient was admitted with a history of pain during neck movements after cervical injury. Computerized tomography scan revealed type II odontoid fracture and fusion anomaly between C2 and C3 vertebrae. At surgery, the anteroinferior part of C2 vertebra corpus could not be reached; therefore, transodontoid screw was advanced from C3 vertebra toward odontoid process. Read More

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http://dx.doi.org/10.4103/jcvjs.JCVJS_54_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364369PMC
February 2019

Differing presenting features of idiopathic intracranial hypertension in the UK and US.

Eye (Lond) 2019 Feb 19. Epub 2019 Feb 19.

Metabolic Neurology, Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, UK.

Aim: Demographic factors potentially influencing the presentation and severity of idiopathic intracranial hypertension (IIH) in the US vs. UK populations include obesity and ethnicity. We aimed to compare the presenting features of IIH between populations in the UK and US tertiary referral centres, to assess what population differences exist and whether these cause different presentations and impact on visual function. Read More

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http://dx.doi.org/10.1038/s41433-019-0359-5DOI Listing
February 2019

Publisher Correction: Pathways to eating in children and adolescents with obesity.

Int J Obes (Lond) 2019 Feb 19. Epub 2019 Feb 19.

Institute of Medical Science, University of Toronto, Toronto, Canada.

In the original version of this Article the following were listed as authors; however, they should have only been referred to in the Acknowledgments section and not listed in this way. Read More

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http://dx.doi.org/10.1038/s41366-019-0338-8DOI Listing
February 2019

Rosiglitazone remodels the lipid droplets and britens human visceral and subcutaneous adipocytes ex vivo.

J Lipid Res 2019 Feb 19. Epub 2019 Feb 19.

Icahn School of Medicine at Mount Sinai, United States.

Treatment with PPARγ agonists in vivo improves human adipocyte metabolism, but the cellular mechanisms and possible depot differences in responsiveness to their effects are poorly understood. To examine the ex vivo metabolic effects of rosiglitazone, we cultured explants of human visceral (omental) and abdominal subcutaneous adipose tissues for 7 days. Rosiglitazone increased mRNA levels of transcriptional regulators of brite/beige adipocytes (PGC1α, PRDM16), triglyceride synthesis (GPAT3, DGAT1), and lipolysis (ATGL), similarly in adipose tissues from both depots. Read More

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http://dx.doi.org/10.1194/jlr.M091173DOI Listing
February 2019

Respiratory chain polymorphisms and obesity in the Spanish population, a cross-sectional study.

BMJ Open 2019 Feb 19;9(2):e027004. Epub 2019 Feb 19.

Genomic and Genetic Diagnosis Unit, Research Foundation of Valencia University Clinical Hospital-INCLIVA, Valencia, Spain.

Objective: To study the association of genes involved in the mitochondrial respiratory chain (MRC) pathway with body mass index (BMI) and obesity risk.

Design: This work studies three cross-sectional populations from Spain, representing three provinces: HORTEGA (Valladolid, Northwest/Centre), SEGOVIA (Segovia, Northwest/centre) and PIZARRA (Malaga,South).

Setting: Forty-eight single nucleotide polymorphisms (SNPs) from MRC genes were selected and genotyped by SNPlex method. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-027004DOI Listing
February 2019

Application of a novel sex independent anthropometric index, termed angle index, in relation to type 2 diabetes: a Trinidadian case-control study.

BMJ Open 2019 Feb 19;9(2):e024029. Epub 2019 Feb 19.

Biochemistry Unit, Department of Preclinical Sciences, Faculty of Medical Sciences, The University of the West Indies, St Augustine, Trinidad and Tobago.

Objective: To develop a novel sex independent anthropometric index, termed as angle index, related to type 2 diabetes.

Design: Case-control.

Participants: The study comprised 121 participants and were divided into two groups. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-024029DOI Listing
February 2019

Pregnancy outcomes of early detected gestational diabetes: a retrospective comparison cohort study, Qatar.

BMJ Open 2019 Feb 19;9(2):e023612. Epub 2019 Feb 19.

Department of Endocrinology, Qatar Metabolic Institute, Hamad Medical Corporation, Doha, Qatar.

Objective: To compare pregnancy outcomes in patients with early versus usual gestational diabetes mellitus (GDM).

Design: A retrospective cohort study.

Settings: The Women's Hospital, Hamad Medical Corporation, Qatar. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-023612DOI Listing
February 2019

Feasibility of working with a wholesale supplier to co-design and test acceptability of an intervention to promote smaller portions: an uncontrolled before-and-after study in British Fish & Chip shops.

BMJ Open 2019 Feb 19;9(2):e023441. Epub 2019 Feb 19.

Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK.

Objectives: To explore the feasibility of working with a wholesale supplier to co-design and deliver, and to assess the acceptability of, an intervention to promote smaller portions in Fish & Chip shops.

Design: Uncontrolled before-and-after study.

Setting: Fish & Chip shops in northern England, 2016. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-023441DOI Listing
February 2019

Do changes in weight status affect cognitive function in children and adolescents with obesity? A secondary analysis of a clinical trial.

BMJ Open 2019 Feb 19;9(2):e021586. Epub 2019 Feb 19.

Liggins Institute, University of Auckland, Auckland, New Zealand.

Objectives: It is unclear whether an association exists between obesity in children/adolescents and cognitive function, and whether the latter can be altered by body mass index (BMI) standard deviation score (SDS) reductions. We aimed to determine whether an association exists between BMI SDS and cognitive function in children/adolescents with obesity engaged in an obesity intervention. Second, we sought to determine if BMI SDS reduction at 12 months was associated with improved cognitive function. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-021586DOI Listing
February 2019

Change in the distribution of body mass index in Brazil: analysing the interindividual inequality between 1974 and 2013.

J Epidemiol Community Health 2019 Feb 19. Epub 2019 Feb 19.

Department of Social and Behavioral Science, Harvard TH Chan School of Public Health, Boston, Massachusets, USA.

Background: Brazil is among the 10 countries with the highest prevalence of overweight in the world. The aim was to analyse the changes in the dispersion of body mass index (BMI) in the Brazilian population from the 1970s to 2013 in specific population groups.

Methods: Data were extracted from five national household surveys between 1974-1975 and 2013, including adults aged 20 to 64. Read More

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http://dx.doi.org/10.1136/jech-2018-211664DOI Listing
February 2019

Parents' perceptions of obesity prevention during infancy: a qualitative study.

CMAJ Open 2019 Jan-Mar;7(1):E81-E87. Epub 2019 Feb 18.

Department of Family Practice (Hale) and School of Population and Public Health (Lee), University of British Columbia; British Columbia Children's Hospital and SCOPE BC (Sustainable Childhood Obesity Prevention through Community Engagement) (Amed, Keidar), Vancouver, BC; East Kootenay Division of Family Practice (Purcell), Cranbrook, BC; College of Medicine (Farhadi), University of Saskatchewan, Saskatoon, Sask.

Background: Infancy appears to be a critical period for establishing a person's weight set point. It remains unclear which interventions during infancy may be most effective in preventing later obesity and which ones are most acceptable to parents. The aim of this study was to examine the attitudes of parents of children aged 2 years and under toward different obesity prevention messages and their preferences with regard to these messages. Read More

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http://dx.doi.org/10.9778/cmajo.20180066DOI Listing
February 2019
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