297,208 results match your criteria Obesity Facts [Journal]


Screening for non-alcoholic fatty liver disease in patients with type 2 diabetes mellitus using transient elastography.

J Gastroenterol Hepatol 2018 Dec 14. Epub 2018 Dec 14.

Gastroenterology and Hepatology Unit, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Background: The recommendation in regards to screening for non-alcoholic fatty liver disease (NAFLD) among type 2 diabetes mellitus (T2DM) patients differs in major guidelines.

Aim: To study the prevalence of NALFD and advanced fibrosis among T2DM patients.

Methods: Cross-sectional study of consecutive adult T2DM patients attending the Diabetes Clinic of a university hospital. Read More

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December 2018

Prevalence and associated risk factors of periodic limb movement in sleep in two German population-based studies.

Sleep 2018 Dec 14. Epub 2018 Dec 14.

Institute of Epidemiology and Social Medicine, Westfälische Wilhelms-Universität Münster, Münster, Germany.

Study Objectives: Periodic limb movements in sleep (PLMS) are frequent motor phenomena; however, population-based data are scarce. We assessed the prevalence of PLMS and factors associated with PLMS within two German population-based cohorts, the SHIP-TREND and BiDirect.

Methods: Single-night polysomnography was performed on 1107 subjects recruited from the general population (mean age: 52. Read More

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December 2018

Social and early life adversity and chronic health conditions among Tunisian adults.

Transl Behav Med 2018 Dec 13. Epub 2018 Dec 13.

Duluth Medical Research Institute, University of Minnesota, Duluth, MN, USA.

Early life adversities (ELAs) are shown as significant risk factors for chronic health conditions (CHCs). ELAs include multiple types of abuse such as the social abuse (peer, community, and collective violence). The purpose is to describe the relationship between childhood social abuse and chronic conditions in adulthood among a sample of adults in Tunisia and to investigate the role of obesity and tobacco use as mediators of this association. Read More

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December 2018

Cytological and molecular aspects of the ageing sperm.

Hum Reprod 2018 Dec 14. Epub 2018 Dec 14.

Laboratory of Seminology - Sperm Bank 'Loredana Gandini' Department of Experimental Medicine, 'Sapienza' University of Rome, Italy.

Study Question: Is ageing associated with a decline in semen quality and molecular changes to human sperm?

Summary Answer: Semen quality declines with advancing age and characteristic molecular changes take place during the ageing process, including increased sperm DNA damage, altered sperm protamination and altered seminal plasma miRNA profile.

What Is Known Already: During ageing, the reproductive system is exposed to physiological changes and potentially damaging factors that may impair testicular function. Reactive oxygen species (ROS) can induce errors during DNA replication, transcription or post-transcriptional events (fragmentation, chromatin condensation abnormalities and protamine expression defects). Read More

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December 2018

Do wearable sensors add meaningful information to the Timed Up and Go test? A study on obese women.

J Electromyogr Kinesiol 2018 Dec 5;44:78-85. Epub 2018 Dec 5.

Rehabilitation Unit and Research Lab in Biomechanics and Rehabilitation, S Giuseppe Hospital, Istituto Auxologico Italiano, Piancavallo, VB, Italy.

The purpose of this study was to validate Time Up and Go test (TUG) as measured by a single Inertial Measurement Unit (IMU) placed on the lower back to that measured by a stopwatch in obese and normal weight women; in addition, the comparison of the performance of TUG test between obese and healthy women using the instrumented TUG (iTUG). Forty-four severely obese women and 14 age-matched healthy women were assessed simultaneously by IMU and stopwatch. The comparison between manual and instrumented assessment of total time duration showed no significant differences both in the healthy (8. Read More

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December 2018

Targeting STATs in neuroinflammation: the Road Less Traveled!

Pharmacol Res 2018 Dec 11. Epub 2018 Dec 11.

Department of Pharmacology, Faculty of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran.

JAK/STAT transduction pathway is a highly conserved pathway implicated in regulating cellular proliferation, differentiation, survival and apoptosis. Dysregulation of this pathway is involved in the onset of autoimmune, haematological, oncological, metabolic and neurological diseases. Over the last few years, the research of anti-neuroinflammatory agents has gained considerable attention. Read More

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December 2018

Role of the androgen receptor gene CAG repeat polymorphism on the sequence of pubertal events and adiposity in girls with high dehydroepiandrosterone sulfate.

J Pediatr Adolesc Gynecol 2018 Dec 11. Epub 2018 Dec 11.

Institute of Maternal and Child Research, School of Medicine, University of Chile, Santiago, Chile. Electronic address:

Study Objective: The Androgen Receptor (AR) harbors a variable repeat of a variable number of glutamine residues [(CAG)n] which seems to affect inversely AR transcriptional activity. We assessed whether (CAG)n affect the sequence of the androgen-sensitive pubertal events and body composition in prepubertal girls.

Design: and participants: Nested case-control study within the Growth and Obesity Cohort Study of 1196 low-middle income children (≈50% girls) from Santiago, Chile. Read More

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December 2018

Identifying notions of environment in obesity research using a mixed-methods approach.

Obes Rev 2018 Dec 14. Epub 2018 Dec 14.

Copenhagen Centre for Health Research in the Humanities, The Saxo Institute, University of Copenhagen, Copenhagen, Denmark.

The recent rise of computation-based methods in social science has opened new opportunities for exploring qualitative questions through analysis of large amounts of text. This article uses a mixed-methods design that incorporates machine reading, network analysis, semantic analysis, and qualitative analysis of 414 highly cited publications on obesogenic environments between 2001 and 2015. The method produces an elaborate network map exhibiting five distinct notions of environment, all of which are currently active in the field of obesity research. Read More

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December 2018

Delivering in-school interventions to improve dietary behaviours amongst 11- to 16-year-olds: A systematic review.

Obes Rev 2018 Dec 14. Epub 2018 Dec 14.

The Staffordshire Centre for Psychological Research and Centre for Health Psychology, Staffordshire University, Stoke-on-Trent, UK.

Childhood obesity is a global health concern, which has both short- and long-term health consequences for the individual, and is a potential burden on health care services and the wider economy. The school environment is a setting where changes can be applied to dietary behaviours, as schools have direct and intensive contact with children. This systematic review evaluated school-based interventions designed to improve dietary behaviours among adolescents (11- to 16-year-olds). Read More

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December 2018

The Health Risks of Obesity Have Not Been Exaggerated.

Med Sci Sports Exerc 2019 Jan;51(1):222-225

Center for Physical Activity and Weight Management, The University of Kansas, University of Kansas Medical Center, Lawrence, KS.

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January 2019

The Health Risks of Obesity Have Been Exaggerated.

Med Sci Sports Exerc 2019 Jan;51(1):218-221

Department of Exercise Science, Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC.

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January 2019

CE: Addressing Food Insecurity in Vulnerable Populations.

Am J Nurs 2018 Dec 12. Epub 2018 Dec 12.

Heather L. Flores is an NP at the John and Ella Byrd McCain Health and Counseling Center, Alabama A&M University, Huntsville. Azita Amiri is an assistant professor of nursing at the University of Alabama, Huntsville. Contact author: Heather L. Flores, The authors and planners have disclosed no potential conflicts of interest, financial or otherwise.

A review of risk factors, health effects, screening, and resources. ABSTRACT: Food insecurity affects people of all ages, in every area in which nurses work or volunteer. The U. Read More

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December 2018

Nanoparticle-mediated lysosomal reacidification restores mitochondrial turnover and function in β cells under lipotoxicity.

FASEB J 2018 Dec 14:fj201801292R. Epub 2018 Dec 14.

Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer-Sheva, Israel.

Chronic exposure of pancreatic β cells to high concentrations of free fatty acids leads to lipotoxicity (LT)-mediated suppression of glucose-stimulated insulin secretion. This effect is in part caused by a decline in mitochondrial function as well as by a reduction in lysosomal acidification. Because both mitochondria and lysosomes can alter one another's function, it remains unclear which initiating dysfunction sets off the detrimental cascade of LT, ultimately leading to β-cell failure. Read More

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December 2018

Eating pathology and psychological outcomes in young adults in self-regulation interventions using daily self-weighing.

Health Psychol 2018 Dec 13. Epub 2018 Dec 13.

Warren Alpert Medical School.

Objective: Self-regulation interventions encouraging daily weighing prevent weight gain in young adults; however, concerns have been raised that such interventions may have undesirable effects on eating pathology, depression, and health-related quality of life (HRQL). The present study examined whether self-regulation interventions and self-weighing frequency were associated with these indices in normal weight individuals and those with overweight or obesity.

Methods: Young adults ( = 599), 18-35 years with a body mass index (BMI) 21. Read More

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December 2018

[Application of da Vinci robot's bilateral axillo-breast approach in thyroid surgery of obese patients].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Jul;32(14):1061-1065

Departmeng of Thyroid and Breast Surgery, Jinan Military General Hospital, Jinan, 250031, China.

To discuss the effect of obesity on the operation of thyroid gland surgery and surgical results.The clinical data of 446 patients who underwent robot thyroid surgery through bilateral axillo-breast approach (BABA) from the General Hospital of Jinan Military region from February 2014 to November 2017 were analyzed retrospectively, and the patients were divided into BMI<25 kg/m²; group, BMI 25-30 kg/m²; group and BMI>30 kg/m²; group according to body mass index (BMI). The operative complications were compared between the three groups of benign and malignant patients, such as operation time, postoperative lead flow, postoperative hospitalization time, tumor size (malignant), lymph node metastasis (malignant), cosmetic satisfaction score, laryngeal nerve injury and parathyroid function decrease. Read More

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[Position paper on taxes to non-basic energy-dense foods and sugar-sweetened beverages].

Salud Publica Mex 2018 Sep-Oct;60(5):586-591

Dirección General, Instituto Nacional de Salud Pública. México.

In 2014 the Mexican government implemented taxes to reduce the consumption of sugar-sweetened beverages and nonessential energy-dense foods. In this manuscript, we analyze the scientific evidence linking the consumption of these products to chronic diseases, and summarize the studies that have evaluated the observed and expected impact of food taxes in Mexico. The implementation of taxes to unhealthy foods has reduced purchases of sugar-sweetened beverages in 7. Read More

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Assessment of Serum Vitamin D and Irisin Levels in Obese Patients.

Clin Lab 2018 Oct;64(11)

Background: 25-hydroxyvitamin D and irisin have been found to be involved in the pathogenesis of obesity. The aim of the study is to assess the serum levels of 25-hydroxyvitamin D and irisin in obese patients and to determine the association of 25-hydroxyvitamin D and irisin levels with anthropometric parameters. Methods: The study was carried out on 300 obese patients in addition to 156 healthy age and gender matched subjects as a control group. Read More

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October 2018

Elevated circulating cathepsin S levels are associated with metabolic syndrome in overweight and obese individuals.

Diabetes Metab Res Rev 2018 Dec 14:e3117. Epub 2018 Dec 14.

Department of Endocrinology, Huashan Hospital Fudan University.

Objective: Cathepsin S is highly expressed in subcutaneous and visceral adipose tissue. Cathepsin S correlates with central obesity and contributes to the formation and progression of atherosclerosis. Here, we sought to evaluate the association of serum cathepsin S with metabolic syndrome (MS) in overweight and obese Chinese adults. Read More

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December 2018

Waist circumference and abdominal volume index are the strongest anthropometric discriminators of metabolic syndrome in Spanish adolescents.

Eur J Clin Invest 2018 Dec 14:e13060. Epub 2018 Dec 14.

Department of Nursing, University of Granada, Av. Ilustración, 60, 18016, Granada, Spain.

Background: Waist circumference has been suggested as predictor for metabolic syndrome (MetS) in adolescents but it has not been compared with newly proposed anthropometric indexes. This study aimed to disclose the capacity of ten classic and novel anthropometric indexes to discriminate by the presence of MetS in this young population.

Materials And Methods: A cross-sectional study was performed on 981 adolescents (13. Read More

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December 2018

Structural responses to the obesity and non-communicable diseases epidemic: Update on the Chilean law of food labelling and advertising.

Obes Rev 2018 Dec 13. Epub 2018 Dec 13.

Institute of Nutrition and Food Technology (INTA), University of Chile, Santiago, Chile.

Chile approved the law of food labelling and advertising in 2012; this law aims to address the obesity epidemic, particularly in children. The implementation details were published in 2015, and the law was implemented finally in 2016, as described in the current article. Regulated foods were defined based on a specially developed nutrient profiling, which considered natural foods as gold standard. Read More

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December 2018

Preconception management of women with obesity: A systematic review.

Obes Rev 2018 Dec 13. Epub 2018 Dec 13.

Department of Medicine (Austin Health), University of Melbourne, Heidelberg Heights, Victoria, Australia.

The prevalence of women of child-bearing age with obesity continues to rise at an alarming rate. This has significant implications for both the short-term and long-term health of mother and offspring. Given the paucity of evidence-based literature in this field, the preconception management of women with obesity is highly variable both between institutions and around the world. Read More

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December 2018

The effect of body condition on postoperative recovery of dachshunds with intervertebral disc disease treated with postoperative physical rehabilitation.

Vet Surg 2018 Dec 13. Epub 2018 Dec 13.

College of Veterinary Medicine, University of Illinois, Urbana-Champaign, Illinois.

Objective: To determine the impact of obesity on postoperative recovery from thoracolumbar hemilaminectomy in dachshunds treated with rehabilitation.

Study Design: Prospective observational trial.

Animals: Thirty-two dachshunds with thoracolumbar intervertebral disk disease and pain perception. Read More

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December 2018

Insights into the Pulmonary Vascular complications of heart failure with Preserved Ejection Fraction.

J Physiol 2018 Dec 13. Epub 2018 Dec 13.

Pittsburgh Heart, Lung, Blood and Vascular Medicine Institute, University of Pittsburgh, Pittsburgh, PA, USA.

Pulmonary hypertension in the setting of heart failure with preserved ejection fraction (PH-HFpEF) is a growing public health problem that is increasing in prevalence. While PH-HFpEF is defined by a high mean pulmonary artery pressure, high left ventricular end-diastolic pressure and a normal ejection fraction, some HFpEF patients develop PH in the presence of pulmonary vascular remodeling with a high transpulmonary pressure gradient or pulmonary vascular resistance. Aging, increased left atrial pressure and stiffness, mitral regurgitation, as well as features of metabolic syndrome, which include obesity, diabetes, and hypertension, are recognized as risk factors for PH-HFpEF. Read More

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December 2018

Clinical Features Related to Statin-Associated Muscle Symptoms.

Muscle Nerve 2018 Dec 13. Epub 2018 Dec 13.

Departments of Pediatrics, Neurology, and Pathology & Anatomical Sciences, University at Buffalo, Buffalo, NY, 14214, USA.

Introduction: Statins reduce cardiovascular disease risk and are generally well-tolerated, yet up to 0.5% of statin-treated patients develop incapacitating muscle symptoms including rhabdomyolysis. Our objective was to identify clinical factors related to statin-associated muscle symptoms (SAMS). Read More

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December 2018

Contribution of Adipose Tissue Inflammation to the Development of Type 2 Diabetes Mellitus.

Compr Physiol 2018 Dec 13;9(1):1-58. Epub 2018 Dec 13.

Cancer Prevention Program, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

The objective of this comprehensive review is to summarize and discuss the available evidence of how adipose tissue inflammation affects insulin sensitivity and glucose tolerance. Low-grade, chronic adipose tissue inflammation is characterized by infiltration of macrophages and other immune cell populations into adipose tissue, and a shift toward more proinflammatory subtypes of leukocytes. The infiltration of proinflammatory cells in adipose tissue is associated with an increased production of key chemokines such as C-C motif chemokine ligand 2, proinflammatory cytokines including tumor necrosis factor α and interleukins 1β and 6 as well as reduced expression of the key insulin-sensitizing adipokine, adiponectin. Read More

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December 2018

What young Australians think about a tax on sugar-sweetened beverages.

Aust N Z J Public Health 2018 Dec 13. Epub 2018 Dec 13.

School of Medicine, Deakin University, Victoria.

Objective: To determine support for a tax on sugar-sweetened beverages (SSBs) among young Australian adults and the potential impact on SSB consumption if a tax is introduced.

Methods: Cross-sectional convenience survey of Australians aged 18-30 years sampled in the City of Greater Geelong, Australia, in November-December 2017.

Results: A total of 1,793 responses were recorded. Read More

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December 2018

Cross-talk of healthy and impaired human tissues for dissection of disease pathogenesis.

Biotechnol Prog 2018 Dec 13:e2766. Epub 2018 Dec 13.

Venetian Institute of Molecular Medicine, Via Orus 2, 35131, Padova, Italy.

Systemic diseases affect multiple tissues that interact with each other within a network difficult to explore at the body level. However, understanding the inter-dependences between tissues could be of high relevance for drug target identification, especially at the first stages of disease development. In vitro systems have the advantages of accessibility to measurements and precise controllability of culture conditions, but currently have limitations in mimicking human in vivo systemic tissue response. Read More

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December 2018

Call for Analysis of Look AHEAD Data.

Authors:

Obesity (Silver Spring) 2018 Dec 12. Epub 2018 Dec 12.

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December 2018

Clinical indices and local levels of inflammatory biomarkers in per-implant health of obese and nonobese individuals.

Clin Implant Dent Relat Res 2018 Dec 13. Epub 2018 Dec 13.

Department of Periodontology, Faculty of Dentistry, Ziauddin University, Karachi, Pakistan.

Background: Obesity seem to regulate peri-implant health. It is proposed that peri-implant crevicular fluid (PICF) levels of interleukin (IL)-1β and IL-6 are higher in obese as compared to nonobese individuals.

Objective: The purpose of the present clinico-laboratory study is to estimate and compare the clinical and radiographic indices and PICF levels of IL-1β and IL-6 among obese and nonobese patients. Read More

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December 2018

Do lifestyle interventions during pregnancy have the potential to reduce long-term postpartum weight retention? A systematic review and meta-analysis.

Obes Rev 2018 Dec 12. Epub 2018 Dec 12.

Else Kroener-Fresenius Center for Nutritional Medicine, University Hospital Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

Reducing postpartum weight retention is a promising strategy for addressing the rising prevalence of overweight and obesity in women. This systematic review and meta-analysis explored whether lifestyle interventions during pregnancy have the potential to reduce weight retention at 4 months postpartum and beyond. A search of five electronic databases for randomized controlled trials comparing the effect of weight-related lifestyle interventions beginning in pregnancy on postpartum weight retention to standard prenatal care groups was performed. Read More

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December 2018

Predicting Infections in Chronic Leg Ulcers: A Step Ahead.

Int J Clin Pract 2018 Dec 12:e13304. Epub 2018 Dec 12.

New York University School of Medicine, Department of Biochemistry and Molecular Pharmacology.

Chronic wounds, often called ulcers, are a worldwide challenge and were recently referred to as a silent epidemic [1-4]. They have been classified into vascular, diabetic, and pressure ulcers, have a significant impact on the individual, the healthcare system, and society as a whole [5-7], and affect virtually all aspects of life [8, 9]. The medical and socioeconomic impact of chronic ulcers is escalating worldwide, a trend at least partly driven by escalating health care costs, an aging population, an increase in the incidence of diabetes, and the obesity pandemic [1, 10, 11]. Read More

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December 2018

Long-term safety and drug survival of acitretin in psoriasis: a retrospective observational study.

Int J Dermatol 2018 Dec 13. Epub 2018 Dec 13.

Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Background: This retrospective observational study aimed to investigate the long-term safety, drug survival, and factors associated with the survival of acitretin in a real-world setting.

Methods: Data of adult patients with psoriasis who attended Siriraj Hospital between 2012 and 2017 and were treated with acitretin were reviewed. Demographic data and clinical courses were recorded. Read More

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December 2018

Comparability of published cut-points for the assessment of physical activity: Implications for data harmonization.

Scand J Med Sci Sports 2018 Dec 12. Epub 2018 Dec 12.

PROFITH ''PROmoting FITness and Health through physical activity'' Research Group, Department of Physical and Sports Education, Faculty of Sports Science, University of Granada, Ctra. Alfacar s/n, 18011, Granada, Spain.

This study aimed to compare estimations of sedentary time (SED) and time spent in physical activity (PA) intensities in children with overweight/obesity across different age-appropriate cut-points based on different body-worn attachment sites and acceleration metrics. A total of 104 overweight/obese children (10.1±1. Read More

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December 2018

Brown adipose tissue thermogenesis in polycystic ovary syndrome.

Clin Endocrinol (Oxf) 2018 Dec 12. Epub 2018 Dec 12.

Department of Physiology, Monash University, Melbourne, Victoria, Australia.

Objective: Polycystic ovary syndrome (PCOS) is associated with increased obesity with a greater propensity to weight gain and a lack of sustainable lifestyle interventions. Altered brown adipose tissue (BAT) thermogenesis is a potential contributor to obesity in PCOS. BAT activity and modulation has not been studied in PCOS. Read More

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December 2018
1 Read

Global patterns in excess body weight and the associated cancer burden.

CA Cancer J Clin 2018 Dec 12. Epub 2018 Dec 12.

Scientific Vice President, Surveillance and Health Services Research, American Cancer Society, Atlanta, GA.

The prevalence of excess body weight and the associated cancer burden have been rising over the past several decades globally. Between 1975 and 2016, the prevalence of excess body weight in adults-defined as a body mass index (BMI) ≥ 25 kg/m -increased from nearly 21% in men and 24% in women to approximately 40% in both sexes. Notably, the prevalence of obesity (BMI ≥ 30 kg/m ) quadrupled in men, from 3% to 12%, and more than doubled in women, from 7% to 16%. Read More

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December 2018

Excessive Gestational Weight Gain.

J Midwifery Womens Health 2018 Dec 12. Epub 2018 Dec 12.

Excessive gestational weight gain (GWG) is associated with an increasing incidence of maternal and neonatal complications, including hypertensive disorders of pregnancy, fetal macrosomia, and increased cesarean birth rates. In the United States, it is recommended that health care providers use an individualized approach to counsel a woman about pregnancy weight gain goals that is based on the woman's initial body mass index (BMI) and to track GWG throughout the pregnancy by evaluating maternal weight at each visit. Studies have shown that women entering pregnancy with a higher BMI are at increased risk for excessive GWG and postpartum weight retention. Read More

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December 2018

Microbes: possible link between modern lifestyle transition and the rise of metabolic syndrome.

Obes Rev 2018 Dec 11. Epub 2018 Dec 11.

Department of Internal Medicine, Division of Gastroenterology, Rush University Medical Center, Chicago, IL, USA.

The rapid decrease in infectious diseases globally has coincided with an increase in the prevalence of obesity and other components of metabolic syndrome. Insulin resistance is a common feature of metabolic syndrome and can be influenced by genetic and non-genetic/environmental factors. The emergence of metabolic syndrome epidemics over only a few decades suggests a more prominent role of the latter. Read More

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December 2018

Association between life span and body condition in neutered client-owned dogs.

J Vet Intern Med 2018 Dec 11. Epub 2018 Dec 11.

Institute of Ageing and Chronic Disease, University of Liverpool, Cheshire, United Kingdom.

Background: There is an association between overweight status and life span in kenneled dogs, but a similar association has not been reported for pet dogs.

Objectives: To examine the effects of being overweight in middle age on the life span of neutered client-owned dogs.

Animals: Fifty-thousand seven-hundred eighty seven middle-aged neutered client-owned dogs attending a network of approximately 900 veterinary hospitals across North America. Read More

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December 2018

Interaction of body mass index or waist-to-hip ratio and sun exposure associated with nonmelanoma skin cancer: A prospective study from the Women's Health Initiative.

Cancer 2018 Dec 11. Epub 2018 Dec 11.

Division of Dermatology, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California.

Background: The incidence of nonmelanoma skin cancer (NMSC) exceeds the incidence of all other types of cancers combined. Cumulative sun exposure and intermittent sun exposure are known risk factors for the development of NMSC. Because obesity has been shown to decrease the risk of NMSC incidence, this study investigated whether the risk of NMSC with sun exposure was consistent across different levels of body size. Read More

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December 2018

TNF, but not hyperinsulinemia or hyperglycemia, is a key driver of obesity-induced monocytosis revealing that inflammatory monocytes correlate with insulin in obese male mice.

Physiol Rep 2018 Dec;6(23):e13937

Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Canada.

Inflammation contributes to obesity-related hyperinsulinemia and insulin resistance, which often precede type 2 diabetes. Inflammation is one way that obesity can promote insulin resistance. It is not clear if the extent of obesity, hyperinsulinemia, or hyperglycemia, underpins changes in cellular immunity during diet-induced obesity. Read More

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December 2018

Laparoscopic artificial urinary sphincter implantation in women with stress urinary incontinence: update on 13 years experience in a single center.

BJU Int 2018 Dec 11. Epub 2018 Dec 11.

Clinique du Pré, Dept of Urology, Technopôle Université, 13 Avenue René Laennec, 72018, Le Mans, France.

Introduction: Stress urinary incontinence (SUI) mainly affects women as a result of pregnancies with laborious delivery, obesity, and pelvic floor dysfunctions. The first therapeutic approach includes life-style interventions, pelvic floor muscle or bladder training. The second-line treatment usually is surgical. Read More

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December 2018

New therapeutic strategy of hinokitiol in haemorrhagic shock-induced liver injury.

J Cell Mol Med 2018 Dec 8. Epub 2018 Dec 8.

Division of General Surgery, Department of Surgery, Taipei Medical University Hospital, Taipei, Taiwan.

Haemorrhagic shock and resuscitation (HS/R) may cause global ischaemia-reperfusion injury, which can result in systemic inflammation, multiorgan failure (particularly liver failure) and high mortality. Hinokitiol, a bioactive tropolone-related compound, exhibits antiplatelet and anti-inflammatory activities. Targeting inflammatory responses is a potential strategy for ameliorating hepatic injury during HS/R. Read More

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December 2018

Experiences of Obese Adolescents trying to Reach a Healthy Weight: Considerations for the Development of a Curriculum Guide.

P R Health Sci J 2018 Dec;37(4):208-212

School of Education, Interamerican University of Puerto Rico, Metro Campus, San Juan, PR.

Objective: Obesity, almost all around the world, has been described by the medical authorities as the most common pediatric illness in children and youngsters. The purpose of this study is to explore, describe, and analyze the experiences of obese adolescents on being obese and trying to reach a healthy weight.

Design And Methods: A convenience sample of eight obese adolescents from 15 to 17 years old of both genders from three high schools of the educational region of San Juan, Puerto Rico was obtained. Read More

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December 2018

Visceral Adiposity Index is not Superior over Anthropometric Parameters with regards to Inflammation in Healthy Adolescent Girls.

P R Health Sci J 2018 Dec;37(4):195-199

Department of Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, Belgrade, Serbia.

Objective: Better than simple anthropometric parameters, the visceral adiposity index (VAI) has recently been proposed as a predictor of cardiometabolic risk in adults. However, there are conflicting results on the associations of these parameters in children and adolescents. Therefore, we aimed to estimate this potential relationship between VAI, anthropometric parameters (i. Read More

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December 2018

Obesity and inflammation.

Eur Cytokine Netw 2018 Sep;29(3):83-94

Department of Gastroenterology, Human Nutrition and Internal Medicine, Poznan University of Medical Sciences, Fredry 10, Poznan 61-701, Poland.

The prevalence of obesity has recently increased dramatically and has contributed to the increasing prevalence of various pathological conditions, including type 2 diabetes mellitus, nonalcoholic fatty liver disease, asthma, various types of cancer, cardiovascular and neurodegenerative diseases, and others. Accumulating evidence points to localized inflammation in adipose tissue, which, in turn, promotes systemic low-grade inflammation as a primary force contributing to the development of these pathologies. A better understanding of the underlying mechanisms behind obesity-induced adipose tissue inflammation is required to develop effective therapeutic or prophylactic strategies. Read More

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September 2018

Cytokines and male infertility.

Eur Cytokine Netw 2018 Sep;29(3):73-82

Unit of Reproductive Endocrinology, First Department of Obstetrics and Gynecology, Medical School, Aristotle University of Thessaloniki, Greece. "Papageorgiou General Hospital", Ring Road-Nea Efkarpia, 56403 Thessaloniki, Greece.

Many male infertility cases have no apparent cause, being characterized as idiopathic. Both inflammation and obesity have long been associated with infertility. On one hand, inflammation, such as orchitis and male accessory gland infections (MAGIs), are regulated by inflammatory cytokines. Read More

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September 2018

Elevated adiponectin and sTNFRII serum levels can predict progression to hepatocellular carcinoma in patients with compensated HCV1 cirrhosis.

Eur Cytokine Netw 2018 Sep;29(3):112-120

AP-HP, hôpital Jean-Verdier, service d'hépatologie, Bondy, France, Inserm UMR_S 1162, « Génomique fonctionnelle des tumeurs solides », 75005 Paris, France, Université Paris 13, Sorbonne Paris-Cité, « Équipe labellisée Ligue contre le cancer », 93206 Saint-Denis, France.

An obesity-related altered adipose tissue secretion is suggested as a risk factor for hepatocellular carcinoma (HCC) in patients with hepatitis C virus (HCV) cirrhosis. However, no prospective study has yet examined the predictive value of circulating adipokines and immuno-inflammatory biomarkers regarding this risk. This was a case-control study nested in a prospective French national cohort of HCV-infected patients with biopsy-proven compensated cirrhosis. Read More

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September 2018

A hotspots analysis-relation discovery representation model for revealing diabetes mellitus and obesity.

BMC Syst Biol 2018 Dec 14;12(Suppl 7):116. Epub 2018 Dec 14.

Key Laboratory of Symbolic Computation and Knowledge Engineering of Ministry of Education, College of Computer Science and Technology, Jilin University, Changchun, 130012, China.

Background: Nowadays, because of the huge economic burden on society causing by obesity and diabetes, they turn into the most serious public health challenges in the world. To reveal the close and complex relationships between diabetes, obesity and other diseases, search the effective treatment for them, a novel model named as representative latent Dirichlet allocation (RLDA) topic model is presented.

Results: RLDA was applied to a corpus of more than 337,000 literatures of diabetes and obesity which were published from 2007 to 2016. Read More

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December 2018

Subtherapeutic anticoagulation with dabigatran following Roux-en-Y gastric bypass surgery.

J Cardiol Cases 2013 Jul 29;8(1):e49-e50. Epub 2013 Apr 29.

Division of Hematology and Cellular Therapy, West Penn Allegheny Health System, Pittsburgh, PA, USA.

We report a 66-year-old male with a history of Roux-en-Y gastric bypass surgery who began dabigatran for new onset atrial fibrillation. After 5 weeks of therapy, his transesophageal echocardiogram prior to electrocardioversion showed severe spontaneous echo contrast. Cardioversion was postponed and anticoagulant therapy was continued. Read More

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Compendium of the Health and Wellness Coaching Literature.

Am J Lifestyle Med 2018 Nov-Dec;12(6):436-447. Epub 2017 May 19.

Department of Exercise & Sport Sciences, Ithaca College, Ithaca, New York (GAS, SH, KC, LC).

Health and wellness coaching (HWC) for lifestyle behavior change is emerging as a practice, role, and profession, in diverse health care, employee wellness, and community settings. Health care professionals apply HWC as a behavior change methodology for the prevention and treatment of diabetes, hypertension, hyperlipidemia, heart disease, cancer, and other chronic disorders. The purpose of this systematic review was to provide a comprehensive and organized compendium of HWC literature. Read More

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