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    Systematic Proteomic Analysis of Protein Methylation in Prokaryotes and Eukaryotes Revealed Distinct Substrate Specificity.
    Proteomics 2017 Nov 18. Epub 2017 Nov 18.
    The Chemical Proteomics Center and State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
    The studies of protein methylation mainly focus on lysine and arginine residues due to their diverse roles in essential cellular processes from gene expression to signal transduction. Nevertheless, atypical protein methylation occurring on amino acid residues, such as glutamine and glutamic acid, was largely neglected until recently. In addition, the systematic analysis for the distribution of methylation on different amino acids in various species is still lacking, which hinders our understanding of its functional roles. Read More

    Levels of serum retinol binding protein 4 before and after non-surgical periodontal treatment in lean and obese subjects: an interventional study.
    J Clin Periodontol 2017 Nov 18. Epub 2017 Nov 18.
    Service of Endocrinology and Nutrition, University Hospital Doctor Peset-FISABIO, Av. Gaspar Aguilar 90, 46017, Valencia, Spain.
    Aim: We aimed to evaluate serum RBP4 levels before and after periodontal therapy in lean and obese subjects with chronic periodontitis (CP) in order to determine its possible association with periodontitis.

    Materials And Methods: This is an interventional study for which a total of 112 lean and 119 obese subjects were recruited. Patients with CP were evaluated before and after three months of non-surgical periodontal treatment. Read More

    Poor agreement in questionnaire-based diagnostic criteria for adult atopic dermatitis is a challenge when examining cardiovascular comorbidity.
    Allergy 2017 Nov 18. Epub 2017 Nov 18.
    Department of Dermatology and Allergy, Herlev and Gentofte Hospital, University of Copenhagen, Hellerup, Denmark.
    Background: The association between atopic dermatitis (AD) and cardio-metabolic risk factors is not yet established. Furthermore, no validated questionnaire-based method of identifying adults with AD is currently available.

    Objectives: To assess the cardio-metabolic risk in adults with a history of AD by using three different questionnaire-based diagnostic criteria. Read More

    Psychological Aspects of Obesity in Children and Adolescents.
    Indian J Pediatr 2017 Nov 18. Epub 2017 Nov 18.
    Department of Psychiatry, AIIMS, Jodhpur, India.
    Childhood obesity is multi factorial health condition, so the simple evaluation of body fat will not be sufficed to manage the global epidemic of childhood obesity. Literature consistently provides evidence for physical health risks associated with childhood obesity; however in recent times, mental health of the obese children has also gained attention of the researchers as well as clinicians. Obese children experience number of psycho-social problems that significantly affect their quality of life and wellbeing. Read More

    Impact of prolonged overfeeding on skeletal muscle mitochondria in healthy individuals.
    Diabetologia 2017 Nov 17. Epub 2017 Nov 17.
    Pennington Biomedical Research Center, Baton Rouge, LA, USA.
    Aims/hypotheses: Reduced mitochondrial capacity in skeletal muscle has been observed in obesity and type 2 diabetes. In humans, the aetiology of this abnormality is not well understood but the possibility that it is secondary to the stress of nutrient overload has been suggested. To test this hypothesis, we examined whether sustained overfeeding decreases skeletal muscle mitochondrial content or impairs function. Read More

    Migration and Cardiovascular Disease Risk Among Ghanaian Populations in Europe: The RODAM Study (Research on Obesity and Diabetes Among African Migrants).
    Circ Cardiovasc Qual Outcomes 2017 Nov;10(11)
    From Julius Global Health, Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, The Netherlands (D.B., D.E.G., K.K.-G.); School of Public Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana (D.B., P.A.B., E.O.-D.); Department of Public Health, Academic Medical Center, University of Amsterdam, Amsterdam Public Health Research Institute, The Netherlands (C.A., E.B., K.M., K.S.); Department of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom (L.S., J.A.); Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany (M.S., C.G., I.D.); Regional Institute for Population Studies, University of Ghana, Legon, Ghana (A.d.-G.A.); Mother Kevin Postgraduate Medical School, Uganda Martyrs University, Kampala (S.B.); Kumasi Centre for Collaborative Research, Kwame NKrumah University of Science and Technology, Ghana (E.O.-D.); Institute of Tropical Medicine and International Health, Charité-University Medicine Berlin, Germany (F.P.M.); Charite Center for Cardiovascular Research, Berlin, Germany (J.S.); Non-Communicable Disease Research Unit, South African Medical Research Council, Cape Town, South Africa (A.P.K.); and Division of Epidemiology and Biostatistics, School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (K.K.-G.).
    Background: For migrant populations from sub-Saharan Africa, adverse cardiovascular disease (CVD) risk factors have been observed to be higher than found in their home country-based counterparts or among the host populations in high-income countries. Differences in absolute overall CVD risk, however, remain largely unexplained. We, therefore, predicted the differences in 10-year CVD risk among sub-Saharan African migrants (Ghanaians) living in 3 European cities and Ghana. Read More

    Gut roundtable meeting paper: selected recent advances in hepatocellular carcinoma.
    Gut 2017 Nov 17. Epub 2017 Nov 17.
    Programme of Hepatology, CIMA, IdiSNA, CIBERehd, University of Navarra, Pamplona, Spain.
    Hepatocellular carcinoma (HCC) ranks number three among the most frequent causes of death from solid tumors worldwide. With obesity and fatty liver diseases as risk factors on the rise, HCC represents an ever increasing challenge. While there is still no curative treatment for most patients numerous novel drugs have been proposed, but most ultimately failed in phase III trials. Read More

    Are food and drink retailers within NHS venues adhering to NICE Quality standard 94 guidance on childhood obesity? A cross-sectional study of two large secondary care NHS hospitals in England.
    BMJ Open 2017 Nov 16;7(11):e018214. Epub 2017 Nov 16.
    NIHR Bristol Biomedical Research Centre (Nutrition Theme), University Hospitals Bristol NHS Foundation Trust and the University of Bristol, Bristol, UK.
    Objective: To assess whether the food and drink retail outlets in two major National Health Service (NHS) district general hospitals in England adhere to quality statements 1-3 of the UK National Institute for Health and Care Excellence (NICE) quality standard 94.

    Design: Cross-sectional, descriptive study to assess the food and drink options available in vending machines, restaurants, cafes and shops in two secondary care hospitals.

    Main Outcome Measures: Adherence to quality statement 1 whereby the food and drink items available in the vending machines were classified as either healthy or less healthy using the Nutrient Profiling Model (NPM). Read More

    Prevalence and recognition of obesity and its associated comorbidities: cross-sectional analysis of electronic health record data from a large US integrated health system.
    BMJ Open 2017 Nov 16;7(11):e017583. Epub 2017 Nov 16.
    Endocrinology and Metabolism Institute, Cleveland Clinic, Cleveland, Ohio, USA.
    Objective: To determine the prevalence of obesity and its related comorbidities among patients being actively managed at a US academic medical centre, and to examine the frequency of a formal diagnosis of obesity, via International Classification of Diseases, Ninth Revision (ICD-9) documentation among patients with body mass index (BMI) ≥30 kg/m(2).

    Design: The electronic health record system at Cleveland Clinic was used to create a cross-sectional summary of actively managed patients meeting minimum primary care physician visit frequency requirements. Eligible patients were stratified by BMI categories, based on most recent weight and median of all recorded heights obtained on or before the index date of 1July 2015. Read More

    Considerations regarding sarcoidosis in the bariatric surgical patient.
    Surg Obes Relat Dis 2017 Oct 16. Epub 2017 Oct 16.
    Department of Medicine, Division of Pulmonary & Critical Care Medicine, Albany Medical College, Albany, New York.
    The sarcoidosis patient who seeks surgical management for obesity presents many challenges. The interaction between sarcoidosis and obesity complicates both disorders and creates special issues to consider when contemplating surgery. This manuscript will review the approach to pre- and postoperative management of the sarcoidosis patient undergoing bariatric surgery. Read More

    Improvement in quality of life after bariatric surgery: sleeve versus bypass.
    Surg Obes Relat Dis 2017 Oct 16. Epub 2017 Oct 16.
    Department of Surgery, Catharina Hospital, Eindhoven, the Netherlands.
    Background: Obesity is steadily growing to be the largest threat to human health in this century, not only increasing prevalence of obesity-related co-morbidity but also impairing health-related quality of life (QoL). Bariatric surgery has shown to improve co-morbidity as well as QoL.

    Objectives: To assess the differences in improvement in QoL for the 2 most performed procedures: laparoscopic sleeve gastrectomy (SG) and laparoscopic Roux-en-Y gastric bypass (RYGB). Read More

    IGF-1R mRNA expression is increased in obese children.
    Growth Horm IGF Res 2017 Nov 11. Epub 2017 Nov 11.
    Department of Paediatrics, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, SP, Brazil. Electronic address:
    Objectives: Obese children are often taller than age-matched subjects. Reports on GH and IGF-I levels in obese individuals are controversial, with normal and reduced GH-IGF-I levels having been reported in this group of patients. Thus, the aim of this study was to analyse insulin-like growth factor type 1 receptor (IGF-IR) mRNA expression in obese children. Read More

    AMP-Activated Protein Kinase Regulation of the NLRP3 Inflammasome during Aging.
    Trends Endocrinol Metab 2017 Nov 14. Epub 2017 Nov 14.
    Laboratory of Experimental and Molecular Immunology and Neurogenetics (INEM), UMR 7355 CNRS-University of Orleans, Orléans, France and IDM, University of Cape Town, Cape Town, South Africa.
    The NLRP3 inflammasome has recently emerged as an unexpected marker of stress and metabolic risk and has also been implicated in the development of major aging-related diseases such as gout, type 2 diabetes, obesity, cancer, and neurodegenerative and cardiovascular disorders. Several pathways regulating the NLRP3 inflammasome are currently being studied, but how the NLRP3 inflammasome is regulated remains unknown. AMP-activated protein kinase (AMPK), a central regulator of multiple metabolic pathways involved in the pathophysiology of aging and age-related diseases, has emerged as an important integrator of signals controlling inflammation including the inflammasome. Read More

    The effect of a physical activity intervention on preschoolers' fundamental motor skills - A cluster RCT.
    J Sci Med Sport 2017 Nov 11. Epub 2017 Nov 11.
    Faculty of Health Sciences, University of Ottawa, 200 Lees Ave., Ottawa, ON K1N 6N5, Canada; Healthy Active Living and Obesity (HALO) Research Group, Children's Hospital of Eastern Ontario Research Institute, 401 Smyth Rd., Ottawa, ON K1H 5B2, Canada. Electronic address:
    Objectives: To assess the effect of a physical activity intervention delivered in the childcare centres (CC), with or without a parent-driven home physical activity component, on children's fundamental motor skills (FMS).

    Design: Six-month 3-arm cluster randomized controlled trial.

    Methods: Preschoolers were recruited from 18 licensed CC. Read More

    Reduced gene expression of sirtuins and active AMPK levels in children and adolescents with obesity and insulin resistance.
    Obes Res Clin Pract 2017 Nov 14. Epub 2017 Nov 14.
    Metabolic Disorders Research Center, Endocrinology and Metabolism Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran; H. Aliasghar Children's Hospital, Iran University of Medical Sciences, Tehran, Iran.
    Background: Sirtuins, including SIRT1 and SIRT2, are longevity-associated deacetylase enzymes that modulate metabolic homeostasis in response to the cellular energy state. Adenosine monophosphate activated protein kinase (AMPK) and SIRT1 are interrelated and share several common target pathways. This study aimed to evaluate the SIRT1 and SIRT2 gene expression in peripheral blood mononuclear cells (PBMCs) as well as plasma levels of AMPK, in obese children and adolescents. Read More

    Do factors related to participation in physical activity change following restrictive bariatric surgery? A qualitative study.
    Obes Res Clin Pract 2017 Nov 14. Epub 2017 Nov 14.
    School of Physiotherapy and Exercise Science, Faculty of Health Sciences, Curtin University, Perth, Western Australia, Australia.
    Aims: To explore participants' ability to participate in physical activity (PA), and barriers and facilitators to PA, at 12 months following restrictive bariatric surgery, and how these differed from participants' pre-surgery perceptions. Motivators for PA post-surgery were also explored.

    Methods: Qualitative one-on-one in-depth interviews were conducted pre- and 12 months post-surgery. Read More

    Clinic and Home-Based Behavioral Intervention for Obesity in Preschoolers: A Randomized Trial.
    J Pediatr 2017 Nov 14. Epub 2017 Nov 14.
    Department of Pediatrics, Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine, Cincinnati, OH.
    Objective: To test the hypotheses that an innovative skills-based behavioral family clinic and home-based intervention (LAUNCH) would reduce body mass index z score (BMIz) compared with motivational interviewing and to standard care in preschool-aged children with obesity.

    Study Design: Randomized controlled trial with children between the ages of 2 and 5 years above the 95(th) percentile for body mass index for age and sex recruited from 27 pediatrician offices across 10 recruitment cycles between March 12, 2012 and June 8, 2015. Children were randomized to LAUNCH (an 18-session clinic and home-based behavioral intervention), motivational interviewing (delivered at the same frequency as LAUNCH), or standard care (no formal intervention). Read More

    Life after endometrial cancer: A systematic review of patient-reported outcomes.
    Gynecol Oncol 2017 Nov 14. Epub 2017 Nov 14.
    Division of Epidemiology, College of Public Health, The Ohio State University, Columbus, OH, United States. Electronic address:
    Background: Women with endometrial cancer (EC) are the second largest population of female cancer survivors in the United States. However, the outcomes of EC survivors, from the patient perspective, are not well-understood. Therefore, we conducted a systematic review of patient-reported outcomes (PROs) following an EC diagnosis. Read More

    Economy class syndrome: what is it and who are the individuals at risk?
    Rev Bras Hematol Hemoter 2017 Oct - Dec;39(4):349-353. Epub 2017 May 26.
    Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.
    The term 'economy class syndrome' refers to the occurrence of thrombotic events during long-haul flights that mainly occur in passengers in the economy class of the aircraft. This syndrome results from several factors related to the aircraft cabin (immobilization, hypobaric hypoxia and low humidity) and the passenger (body mass index, thrombophilia, oral contraceptives or hormone replacement therapy, cancer), acting together to predispose to excessive blood coagulation, which can result in venous thromboembolism. Several risk factors, both genetic and acquired, are associated with venous thromboembolism. Read More

    Esophagectomy After Weight-Reduction Surgery.
    Thorac Surg Clin 2018 Feb 18;28(1):53-58. Epub 2017 Oct 18.
    Division of Thoracic Surgery, University of Tennessee Health Science Center, 1325 Eastmoreland Avenue, Suite #460, Memphis, TN 38104, USA. Electronic address:
    Obesity is now epidemic worldwide, and an increasing number of patients have undergone a weight-loss procedure. Although obesity is a risk factor for esophageal cancer, there are few reports on esophagectomy after bariatric procedures. Careful understanding of the patient's gastroesophageal anatomy as a result of the bariatric procedure and attention to the creation of the esophageal replacement conduit are fundamental for the success of esophagectomy after bariatric surgery. Read More

    Thoracic Surgery Considerations in Obese Patients.
    Thorac Surg Clin 2018 Feb;28(1):27-41
    Department of Cardiothoracic Surgery, Stanford University, 300 Pasteur Drive, Falk Cardiovascular Research Building, 2nd Floor, Stanford, CA 94305, USA. Electronic address:
    The obesity epidemic in the United States has increased greatly over the past several decades, and thoracic surgeons are likely to see obese patients routinely in their practices. Obesity has direct deleterious health effects such as metabolic disorder and cardiovascular disease, and is associated with many cancers. Obese patients who need thoracic surgery pose practical challenges to many of the routine elements in perioperative management. Read More

    Preoperative Risk Factors Associated With Urinary Complications After Kidney Transplantation.
    Transplant Proc 2017 Nov;49(9):2018-2024
    U1195, University Paris Sud, INSERM, Université Paris-Saclay, Le Kremlin-Bicetre, France.
    Background: Only surgically irrelevant risk factors including sex, African-American ancestry, or exceptional U-stitch anastomosis have been identified to associate with urinary complications after kidney transplantation. The objective was to identify modifiable and nonmodifiable risk factors associated with urinary complications after kidney transplantation.

    Methods: A single-center study of 3,129 kidney transplants performed over 40 years was conducted to identify independent risk factors using χ(2) tests and logistic regression analysis. Read More

    Physical activity and calorie intake mediate the relationship from depression to body fat mass among female Mexican health workers.
    Int J Behav Nutr Phys Act 2017 Nov 17;14(1):160. Epub 2017 Nov 17.
    Unidad de Investigación Epidemiológica y en Servicios de Salud, Instituto Mexicano del Seguro Social, Boulevard Benito Juárez No. 31. Centro. C.P., 62000, Cuernavaca, Morelos, Mexico.
    Background: Depression is a foremost cause of morbidity throughout the world and the prevalence of depression in women is about twice as high as men. Additionally, overweight and obesity are major global health concerns. We explored the relationship between depression and body fat, and the role of physical activity and diet as mediators of this relationship in a sample of 456 adult female Mexican health workers. Read More

    Observation and assessment of the nutritional quality of 'out of school' foods popular with secondary school pupils at lunchtime.
    BMC Public Health 2017 Nov 17;17(1):887. Epub 2017 Nov 17.
    MRC/CSO Social & Public Health Sciences Unit, University of Glasgow, Glasgow, UK.
    Background: The contemporary Scottish diet is unhealthy and a risk factor for poor health outcomes including obesity. Over a third of Scottish children are at risk of being overweight or obese, and there have been calls to strengthen the evidence base on the role of the food retail environment around schools in influencing the consumption of unhealthy foods.

    Methods: We examined the food retail environment around five secondary schools in Glasgow city, Scotland. Read More

    First case report of Cohen syndrome in the Tunisian population caused by VPS13B mutations.
    BMC Med Genet 2017 Nov 17;18(1):134. Epub 2017 Nov 17.
    Service des Maladies Congénitales et Héréditaires, CHU Mongi Slim La Marsa, Sidi Daoud La Marsa, 2046, Tunis, Tunisia.
    Background: Cohen syndrome is a rare autosomal recessive developmental disorder that comprises variable clinical features counting developmental delay, pigmentary retinopathy, myopia, acquired microcephaly, truncal obesity, joint hypermobility, friendly disposition and intermittent neutropenia. VPS13B (vacuolar protein sorting 13, yeast, homologue of B) gene is the only gene responsible for Cohen Syndrome, causative mutations include nonsense, missense, indel and splice-site variants. The integrity of the Golgi apparatus requires the presence of the peripheral membrane protein VPS13B that have an essential function in intracellular protein transport and vesicle-mediated sorting. Read More

    Male Breast Cancer and Hyperestrogenemia: A Thirteen-Year Review.
    World J Oncol 2014 Apr 6;5(2):55-61. Epub 2014 May 6.
    Division of Hematology and Medical Oncology, University of Florida, Jacksonville, FL, USA.
    Background: Male breast cancer (MBC) is a very rare malignancy and accounts for 0.1% of all male cancers. MBC has not been studied as extensively as its female counterpart. Read More

    Female Body Mass Index and its Relationship With Triple Negative Breast Cancer and Ethnicity.
    World J Oncol 2013 Oct 27;4(4-5):188-193. Epub 2013 Sep 27.
    Department Chair, Division of Hematology and Oncology, University of Florida, College of Medicine, Jacksonville, Fl, USA.
    Background: Breast cancer in women is a relatively common malignancy in the western hemisphere and is perhaps one of the leading causes of mortality among females. We conducted a retrospect cohort study to investigate the association of body mass index (BMI) with triple negative breast cancer and ethnicity.

    Methods: Tumor Registry Database at the University of Florida, College of Medicine in Jacksonville was utilized for our cohort study. Read More

    Kidney Cancer: Current Progress in Treatment.
    World J Oncol 2011 Aug 24;2(4):158-165. Epub 2011 Aug 24.
    Faculty of Pharmacy, Adina Institute of Pharmaceutical Sciences, Sagar, M.P. - 470002, India.
    Kidney cancer accounts for approximately 2% of all cancers worldwide, with renal cell carcinoma being the most widespread form. Worldwide, the occurrence and mortality rates are rising by 2-3% per decade. Cigarette smoking, obesity, acquired cystic kidney disease and inherited vulnerability are identified risk issues for kidney cancer. Read More

    Perceptions of general and postpresidential election discrimination are associated with loss of control eating among racially/ethnically diverse young men.
    Int J Eat Disord 2017 Nov 17. Epub 2017 Nov 17.
    The Prevention Science Institute, University of Oregon, Eugene, Oregan.
    Objective: The purpose of this study was to examine the association between young men's perceived experiences with discrimination, both general and following the 2016 presidential election, and their loss of control (LOC) eating. The degree to which men identified with their ethnic identity was evaluated as a moderator.

    Method: The sample included 798 men (18-30 years; M = 24. Read More

    Melatonin alleviates adipose inflammation through elevating α-ketoglutarate and diverting adipose-derived exosomes to macrophages in mice.
    J Pineal Res 2017 Nov 17. Epub 2017 Nov 17.
    College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi, 712100, China.
    Obesity is associated with macrophage infiltration and metabolic inflammation, both of which promote metabolic disease progression. Melatonin is reported to possess anti-inflammatory properties by inhibiting inflammatory response of adipocytes and macrophages activation. However, the effects of melatonin on the communication between adipocytes and macrophages during adipose inflammation remain elusive. Read More

    Effects of a healthy-eater self-schema and nutrition literacy on healthy-eating behaviors among Taiwanese college students.
    Health Promot Int 2017 Nov 14. Epub 2017 Nov 14.
    Department of Nursing, Chang Gung University of Science and Technology, Tao-Yuan 33303, Taiwan.
    Unhealthy eating behaviors contribute to obesity and chronic illness. This study examined the relative contributions of a healthy-eater self-schema (a self-conception as a healthy eater) and nutrition literacy on healthy-eating behaviors and whether nutrition literacy was a mediator among Taiwanese college students. A total of 1216 undergraduate students from six universities in Taiwan participated in the study from April to June 2016. Read More

    Pancreatic cancer incidence trends: evidence from the Surveillance, Epidemiology and End Results (SEER) population-based data.
    Int J Epidemiol 2017 Nov 14. Epub 2017 Nov 14.
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20850, USA.
    Background: Annual pancreatic cancer incidence rates have been increasing. We examine pancreatic cancer incidence trends by demographics and histologic type.

    Methods: Data from the Surveillance, Epidemiology and End Results (SEER) registries were available to assess temporal trends and pancreatic cancer rates from 1974 to 2013. Read More

    Invited Commentary: Gestational Hypertension and Diabetes-A Major Public Health Concern.
    Am J Epidemiol 2017 Nov;186(10):1125-1128
    The obesity epidemic in the United States and other countries has contributed to an increase in the rates of gestational diabetes and hypertension. In the past, it was thought that most cases of gestational diabetes and hypertension would resolve after completion of pregnancy. In this issue of the Journal, Pace et al. Read More

    The Association between Food Addiction and Early Maladaptive Schemas in Overweight and Obese Women: A Preliminary Investigation.
    Nutrients 2017 Nov 17;9(11). Epub 2017 Nov 17.
    Department of Human Science, European University of Rome, Via degli Aldobrandeschi 190, 00163 Roma, Italy.
    In recent years, there has been a growing focus on early maladaptive schemas (EMSs) as core features associated with eating psychopathology. The aims of the present study were to assess in overweight and obese women: (i) the association between dysfunctional eating patterns (i.e. Read More

    Adherence to Hunger Training over 6 Months and the Effect on Weight and Eating Behaviour: Secondary Analysis of a Randomised Controlled Trial.
    Nutrients 2017 Nov 17;9(11). Epub 2017 Nov 17.
    Department of Human Nutrition, University of Otago, Dunedin 9054, New Zealand.
    Monitoring blood glucose prior to eating can teach individuals to eat only when truly hungry, but how adherence to 'hunger training' influences weight loss and eating behaviour is uncertain. This exploratory, secondary analysis from a larger randomized controlled trial examined five indices of adherence to 'hunger training', chosen a priori, to examine which adherence measure best predicted weight loss over 6 months. We subsequently explored how the best measure of adherence influenced eating behavior in terms of intuitive and emotional eating. Read More

    Kappaphycus alvarezii as a Food Supplement Prevents Diet-Induced Metabolic Syndrome in Rats.
    Nutrients 2017 Nov 17;9(11). Epub 2017 Nov 17.
    Functional Foods Research Group, Institute for Agriculture and the Environment, University of Southern Queensland, Toowoomba, QLD 4350, Australia.
    The red seaweed, Kappaphycus alvarezii, was evaluated for its potential to prevent signs of metabolic syndrome through use as a whole food supplement. Major biochemical components of dried Kappaphycus are carrageenan (soluble fiber ~34.6%) and salt (predominantly potassium (K) 20%) with a low overall energy content for whole seaweed. Read More

    Metabolic Profile in Patients with Mild Obstructive Sleep Apnea.
    Metab Syndr Relat Disord 2017 Nov 17. Epub 2017 Nov 17.
    1 Disciplina de Medicina e Biologia do Sono, Departamento de Psicobiologia, Universidade Federal de São Paulo , São Paulo, Brazil .
    Background: Mild obstructive sleep apnea (OSA) is a highly prevalent disorder in adults. However, it is not clear whether mild OSA has significant metabolic complications. This study examined the prevalence of metabolic syndrome (MS) in patients with mild OSA compared to control group. Read More

    Increased Cellular Aging by 3 Years of Age in Latino, Preschool Children Who Consume More Sugar-Sweetened Beverages: A Pilot Study.
    Child Obes 2017 Nov 17. Epub 2017 Nov 17.
    3 Psychiatry, University of California , San Francisco, San Francisco, CA.
    Background: Previous studies in adults and older children find that sugar-sweetened beverage (SSB) consumption increases risk for obesity and cellular aging, as measured by leukocyte telomere length (LTL).

    Methods: In a previously described, San Francisco-based Latino birth cohort, where telomere length was measured at birth, we evaluate the relationship between beverage consumption (including SSB and 100% fruit juice), obesity, and LTL at 2-3 years old, as well as change in LTL from birth. LTL (T/S Ratio) was measured in 61 children (mean 2. Read More

    CLINICAL ASSESSMENT OF CARDIOVASCULAR DISEASE ASSOCIATED RISK FACTORS IN JIMMATOWN, SOUTHWEST ETHIOPIA; A COMMUNITY BASED CROSS – SECTIONAL STUDY.
    Ethiop Med J 2017 Jan;55(1):3-9
    Introduction: Cardiovascular disease has been identified as emerging epidemic in developing world and Sub-saharan Africa. The prevalence of risk factors associated with cardiovascular disease is not clearly established in our country. We conducted this study to determine the prevalence of cardiovascular disease associated risk factors in Jimma town. Read More

    Perceptions of adults with overweight/obesity and chronic musculoskeletal pain: an interpretative phenomenological analysis.
    J Clin Nurs 2017 Nov 17. Epub 2017 Nov 17.
    Teesside University, Health and Social Care Institute.
    Aims: To gain insight into the lived experience of adults with overweight/obesity and chronic musculoskeletal pain (CMP). Knowledge gained will inform healthcare professionals about the complexity of the weight-pain relationship and enable more effective engagement with this population BACKGROUND: Quantitative studies show links between weight and pain. Adults with overweight/obesity are more likely to experience comorbidity however, qualitative research describing the complexities of the relationship is limited. Read More

    Exome sequence analysis and follow up genotyping implicates rare ULK1 variants to be involved in susceptibility to schizophrenia.
    Ann Hum Genet 2017 Nov 17. Epub 2017 Nov 17.
    Molecular Psychiatry Laboratory, Division of Psychiatry, University College London, London, UK.
    Schizophrenia (SCZ) is a severe, highly heritable psychiatric disorder. Elucidation of the genetic architecture of the disorder will facilitate greater understanding of the altered underlying neurobiological mechanisms. The aim of this study was to identify likely aetiological variants in subjects affected with SCZ. Read More

    [Chronic kidney disease - The relevant information for an occupational physician].
    Med Pr 2017 Nov 8. Epub 2017 Nov 8.
    Gdański Uniwersytet Medyczny / Medical University of Gdansk, Gdańsk, Poland (Katedra i Klinika Nefrologii, Transplantologii i Chorób Wewnętrznych / Department of Nephrology, Transplantology and Internal Medicine).
    For a number of years chronic kidney disease (CKD) has been listed in the group of lifestyle diseases, such as obesity, diabetes, cardiovascular disease and hypertension. It is estimated that in Poland more than 4 million people may suffer from various stages of CKD. Chronic kidney disease may also be a consequence of all the other civilization diseases. Read More

    Effect of the metabolic syndrome on organ damage and mortality in patients with systemic lupus erythematosus: a longitudinal analysis.
    Clin Exp Rheumatol 2017 Oct 18. Epub 2017 Oct 18.
    Department of Medicine, Tuen Mun Hospital, Hong Kong, SAR China.
    Objectives: To study the effect of the metabolic syndrome (MetS) on organ damage and mortality in patients with SLE.

    Methods: Consecutive patients who fulfilled ≥4 ACR criteria for SLE were assessed for the MetS in October 2010. The MetS was defined by the updated joint consensus criteria, using the Asian criteria for central obesity. Read More

    Peri-implant parameters and C-reactive protein levels among patients with different obesity levels.
    Clin Implant Dent Relat Res 2017 Nov 16. Epub 2017 Nov 16.
    Department of General Dentistry, Eastman Institute for Oral Health, University of Rochester, Rochester, New York.
    Background: It is hypothesized that peri-implant conditions are worse with increasing severity of obesity, because systemic low-grade inflammatory marker (C-reactive protein [CRP]) is higher in severe form of obese individuals.

    Purpose: The aim of the cross-sectional retrospective study was to compare clinical and radiographic peri-implant inflammatory parameters in patients with different levels of obesity and correlate these parameters with CRP levels.

    Materials And Methods: Eighty-four patients who participated in this study were divided into 4 groups: class I obese (group 1), class II obese (group 2), class III obese (group 3), and nonobese individuals (group 4) were included. Read More

    In Vivo Validation of a Less Invasive Gastrostimulator.
    Artif Organs 2017 Nov;41(11):E213-E221
    Bio, Electro and Mechanical Systems Department, Université Libre de Bruxelles, Brussels, Belgium.
    Gastrointestinal stimulator implants have recently shown promising results in helping obese patients lose weight. However, to place the implant, the patient currently needs to undergo an invasive surgical procedure. We report a less invasive procedure to stimulate the stomach with a gastrostimulator. Read More

    Mapping brown adipose tissue based on fat water fraction provided by Z-spectral imaging.
    J Magn Reson Imaging 2017 Nov 17. Epub 2017 Nov 17.
    Department of Radiology, University of Illinois at Chicago, Illinois, USA.
    Background: Brown adipose tissue (BAT) has a great relevance in metabolic diseases and has been shown to be reduced in obesity and insulin resistance patients. Currently, Dixon MRI is used to calculate fat-water fraction (FWF) and differentiate BAT from white adipose tissue (WAT). However, it may fail in areas of phase wrapping and introduce fat-water swapping artifacts. Read More

    Being overweight or obese as a risk factor for acute liver injury secondary to acute acetaminophen overdose.
    Pharmacoepidemiol Drug Saf 2017 Nov 17. Epub 2017 Nov 17.
    Mahidol University International College, Nakhon Pathom, Thailand.
    Purpose: Increased incidences of hepatotoxicity have been observed in obese patients with acute acetaminophen overdose. We evaluate whether the status of being overweight or obese is associated with increase in the development of hepatotoxicity and acute liver injury (ALI) in patients with acute acetaminophen overdose.

    Methods: This was a retrospective cohort study comparing the risk of hepatotoxicity and ALI between overweight or obese patients (body mass index [BMI] ≥ 25) and normal BMI patients (BMI ≤ 24. Read More

    Changes in mothers' intended duration of breastfeeding from the prenatal to neonatal periods.
    Birth 2017 Nov 17. Epub 2017 Nov 17.
    Division of Nutrition, Physical Activity, and Obesity, Centers for Disease Control and Prevention, Atlanta, GA, USA.
    Background: Although previous studies suggest that the intentions of mothers to breastfeed during pregnancy strongly predict actual breastfeeding practice, no studies have examined the changes in the intentions of mothers to breastfeed from the prenatal to neonatal periods. The purpose of this study was to examine changes in intended breastfeeding duration from the prenatal to neonatal periods, their association with actual duration, and predictors for shortened duration.

    Methods: The Infant Feeding Practices Study II was a longitudinal study of mothers in the United States. Read More

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