250,383 results match your criteria Nutritional Neuropathy


One-carbon metabolism nutrient intake and the association between body mass index and urinary arsenic metabolites in adults in the Chihuahua cohort.

Environ Int 2018 Dec 12;123:292-300. Epub 2018 Dec 12.

Environmental Science and Engineering, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Curriculum in Toxicology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. Electronic address:

Background: Exposure to inorganic arsenic (iAs) via drinking water is a serious global health threat. Various factors influence susceptibility to iAs-associated health outcomes, including differences in iAs metabolism. Previous studies have shown that obesity is associated with iAs metabolism. Read More

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December 2018
1 Read

'There is no point giving cash to women who don't spend it the way they are told to spend it' - Exploring women's agency over cash in a combined participatory women's groups and cash transfer programme to improve low birthweight in rural Nepal.

Soc Sci Med 2018 Dec 6;221:9-18. Epub 2018 Dec 6.

Institute for Global Health, University College London, 30 Guilford Street, WC1N 1EH, United Kingdom. Electronic address:

Cash transfer programmes form an integral part of nutrition, health, and social protection policies worldwide, but the mechanisms through which they achieve their health and nutritional impacts are incompletely understood. We present results from a process evaluation of a combined participatory women's groups and cash transfer programme to improve low birth weight in rural Nepal. We explored the ways in which context, implementation, and mechanism of the intervention affected beneficiary women's agency over cash transfers. Read More

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December 2018
1 Read

Inflammatory response under zinc deficiency is exacerbated by dysfunction of the Th2 lymphocyte - M2 macrophage pathway.

Immunology 2018 Dec 15. Epub 2018 Dec 15.

Department of Public Health and Environmental Medicine, The Jikei University School of Medicine.

Nutritional zinc deficiency leads to immune dysfunction and aggravates inflammation. However, the underlying mechanism remains unknown. In this study, the relationship between macrophage subtypes (M1 and M2) or helper T lymphocytes (Th1 and Th2) were investigated using the spleen from rats fed zinc-deficient or standard diet. Read More

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December 2018

Feasibility study on direct fermentation of soybean meal by Bacillus stearothermophilus under non-sterile conditions.

J Sci Food Agric 2018 Dec 15. Epub 2018 Dec 15.

School of Food & Biological Engineering, Jiangsu University, Zhenjiang, 212003, China.

Background: To evaluate the feasibility of high-temperature solid-state fermentation using soybean meal (SBM) during the non-sterile process, Bacillus stearothermophilus was employed to assess the nutritional quality and bioactivity of SBM after fermentation.

Results: The fermented SBM (FSBM) without autoclaving showed significant improvements in nutritional quality and bioactivity. The contents of peptides and, crude and soluble proteins increased by 131. Read More

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December 2018
1 Read

Effects of isoquinoline alkaloids from Macleaya cordata on physiological, immunological and inflammatory parameters in healthy beagles: Alkaloids in dog nutrition.

J Anim Physiol Anim Nutr (Berl) 2018 Dec 14. Epub 2018 Dec 14.

Institute of Animal Nutrition, Freie Universität Berlin, Berlin, Germany.

The aim of the study was to investigate nutritional, physiological and immunological effects of a plant-derived blend of isoquinoline alkaloids (Sangrovit® Extra) in healthy dogs. Two groups of healthy, adult beagles (N = 10) were tested in a cross-over experiment, lasting two consecutive three-week periods. The experimental group received 1. Read More

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December 2018

Systematic review of clinician awareness of mycotoxin impact in neural tube defects and best practices for pediatric neurosurgeons: implications for public health and policy.

Childs Nerv Syst 2018 Dec 14. Epub 2018 Dec 14.

Department of Neurosurgery, Baylor College of Medicine; Division of Pediatric Neurosurgery, Texas Children's Hospital, 6701 Fannin St., Ste. 1230, Houston, TX, 77030, USA.

Purpose: In lower-income populations, high rates of neural tube defects (NTDs) are a concern. Nutritional folate deficiencies and mycotoxins in contaminated food supplies increase risk of NTDs. As physicians in public health and involved in the care of children with NTDs, pediatric neurosurgeons have an interest in the treatment and prevention of NTDs. Read More

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December 2018
1 Read

Gender-specific discrepancy in subjective global assessment for mortality in hemodialysis patients.

Sci Rep 2018 Dec 14;8(1):17846. Epub 2018 Dec 14.

Department of Internal Medicine, College of Medicine, Ewha Womans University, Seoul, Korea.

Although subjective global assessment (SGA) is a widely used representative tool for nutritional investigations even among dialysis patients, no studies have examined gender-specific differences in the ability of SGA to predict mortality in hemodialysis (HD) patients. A total of 2,798 dialysis patients were enrolled from clinical research center for end-stage renal disease (CRC for ESRD) between 2009 and 2015. The cohort was divided into two groups based on nutritional status as evaluated by SGA: 'good nutrition' and 'mild to severe malnutrition'. Read More

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December 2018
1 Read

Vascular and cognitive effects of cocoa-rich chocolate in postmenopausal women: a study protocol for a randomised clinical trial.

BMJ Open 2018 Dec 14;8(12):e024095. Epub 2018 Dec 14.

Primary Health Care Research Unit, La Alamedilla Health Center, Institute of Biomedical Research of Salamanca (IBSAL), Health Service of Castilla y León (SACyL), Salamanca, Spain.

Introduction: The intake of polyphenols has certain health benefits. This study will aim to assess the effect of adding a daily amount of chocolate high in cocoa content and polyphenols to the normal diet on blood pressure, vascular function, cognitive performance, quality of life and body composition in postmenopausal women.

Methods And Analysis: Here we plan a randomised clinical trial with two parallel groups involving a total of 140 women between 50 and 64 years in the postmenopausal period, defined by amenorrhoea of ​​at least 12 consecutive months. Read More

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December 2018

Study protocol for a double-blind randomised controlled trial investigating the impact of 12 weeks supplementation with a extract on cholesterol levels in adults with elevated fasting LDL cholesterol who are overweight or have obesity.

BMJ Open 2018 Dec 14;8(12):e022195. Epub 2018 Dec 14.

Department of Nutrition, Dietetics and Food, Monash University, Notting Hill, Victoria, Australia.

Introduction: Hyperlipidaemia, hyperglycaemia and chronic inflammation are risk factors for chronic diseases cardiovascular disease and type 2 diabetes. Polyphenols are bioactive compounds found in marine algae with potential antihyperlipidaemic, antihyperglycaemic and anti-inflammatory effects. The modulation of these risk factors using bioactive polyphenols may represent a useful strategy for disease prevention and management; research in humans, however, remains limited. Read More

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December 2018
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Smaller erector spinae muscle size is associated with inability to recover activities of daily living after pneumonia treatment.

Respir Investig 2018 Dec 11. Epub 2018 Dec 11.

Department of Cardiology, Pulmonology, and Nephrology, Yamagata University School of Medicine, 2-2-2 Iida-Nishi, Yamagata 990-9585, Japan. Electronic address:

Background: Elderly patients who are hospitalized due to pneumonia experience deterioration of their activities of daily living (ADL) during this period; in some cases, this loss of ADL is not recovered at the end of antibiotic treatment. In this study, we examined whether erector spinae muscle cross-sectional area (ESMCSA) measured by computed tomography (CT) could predict a low level of ADL at the end of antibiotic treatment for pneumonia.

Methods: Eighty patients (mean age 74. Read More

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December 2018

Reference TSH levels in Spanish pregnant women. Is it possible to unify criteria?

Endocrinol Diabetes Nutr 2018 Dec 11. Epub 2018 Dec 11.

Servicio de Análisis Clínicos, Hospital do Meixoeiro, Complexo Hospitalario Universitario, Xerencia de Xestión Integrada de Vigo, Vigo (Pontevedra), España.

Introduction: Specific TSH and free thyroxine ranges are needed to adequately assess maternal thyroid function during pregnancy.

Aim: The aim of this review is to review studies reporting data on references TSH and free thyroxine levels in Spanish women during the first trimester of pregnancy.

Material And Methods: Literature search and selection of studies providing reference TSH ranges in the first trimester of pregnancy. Read More

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December 2018

Adherence to low carbohydrate diet in relation to glioma: A case-control study.

Clin Nutr 2018 Nov 30. Epub 2018 Nov 30.

Department of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran; Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran; Obesity and Eating Habits Research Center, Endocrinology and Metabolism Molecular -Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. Electronic address:

Background: Observational studies that investigated the association between adherence to low carbohydrate diet and odds of glioma are sparse. This is particularly relevant in developing countries where dietary carbohydrate intake is very high.

Objective: This study was, therefore, conducted to investigate the association between adherence to low carbohydrate dietary pattern and odds of glioma among Iranian adults. Read More

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November 2018
4.476 Impact Factor

Candida albicans.

Authors:
Duncan Wilson

Trends Microbiol 2018 Dec 11. Epub 2018 Dec 11.

Medical Research Council Centre for Medical Mycology at the University of Aberdeen, Aberdeen Fungal Group, Institute of Medical Sciences, Foresterhill, Aberdeen, UK. Electronic address:

Pathogens often face zinc restriction due to the action of nutritional immunity - host processes which restrict microbial access to key micronutrients such as zinc and iron. Candida albicans scavenges environmental zinc via two pathways. The plasma membrane transporter Zrt2 is essential for zinc uptake and growth in acidic environments. Read More

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December 2018

Social nutrition: an emerging field in insect science.

Curr Opin Insect Sci 2018 Aug 18;28:73-80. Epub 2018 May 18.

School of Agriculture, Food and Wine, The University of Adelaide, Waite Campus, Southern Australia 5005, Australia.

Nutrition is thought to be a major driver of social evolution, yet empirical support for this hypothesis is scarce. Here we illustrate how conceptual advances in nutritional ecology illuminate some of the mechanisms by which nutrition mediates social interactions in insects. We focus on experiments and models of nutritional geometry and argue that they provide a powerful means for comparing nutritional phenomena across species exhibiting various social ecologies. Read More

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August 2018
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Do avian malaria parasites reduce vector longevity?

Curr Opin Insect Sci 2018 Aug 25;28:113-117. Epub 2018 Aug 25.

Estación Biológica de Doñana (EBD-CSIC), Calle Américo Vespucio, 26, E-41092 Seville, Spain; CIBER Epidemiología y Salud Pública (CIBERESP), Seville, Spain.

Avian Plasmodium and malaria-like parasites of the genus Haemoproteus are widespread vector-borne parasites commonly found infecting birds. These parasites impose deleterious effects on their vertebrate hosts compromising their survival. While the interaction between these parasites and their vertebrate hosts has received much attention, the study of those factors determining the consequences of parasite infections in the insect vectors has been traditionally neglected. Read More

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Effects of thermal processing on the structural and functional properties of soluble dietary fiber from whole grain oats.

Food Sci Technol Int 2018 Dec 14:1082013218817705. Epub 2018 Dec 14.

1 School of Food and Biological Engineering, Zhengzhou University of Light Industry, Zhengzhou, People's Republic of China.

Normal pressure steaming, high pressure steaming, microwave, and frying are widely used to deactivate enzyme in the oats, but these thermal processing methods may affect the structural and functional properties of soluble dietary fiber, which contribute greatly to the health benefits of oat foods. The objective of this study was to evaluate the effects of four different thermal processing methods on the structural and functional properties of soluble dietary fiber from whole grain oats. The results showed that the thermal processing resulted in changes on nutritional components of whole grain oats. Read More

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December 2018

Feather and skin development of ostriches Struthio camelus.

J S Afr Vet Assoc 2018 Dec 5;89(0):e1-e5. Epub 2018 Dec 5.

Directorate for Animal Sciences, Western Cape Department of Agriculture.

Information on feather and skin growth is important for the development of mathematical optimisation nutritional models for ostriches. Ostriches (n = 65) were subjected to a four-stage formulated growth diet programme (pre-starter, starter, grower and finisher), with declining protein and energy content. Nine birds were weighed, stunned, exsanguinated, defeathered, skinned and eviscerated at 1, 54, 84, 104, 115, 132 and 287 days of age. Read More

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December 2018
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Pediatric Fatty Liver and Obesity: Not Always Justa Matter of Non-Alcoholic Fatty Liver Disease.

Children (Basel) 2018 Dec 13;5(12). Epub 2018 Dec 13.

Pediatrics Residency Joint Programs, University of Naples Federico II, 80131 Naples, Italy.

Obesity-related non-alcoholic fatty liver disease (NAFLD) represents the most common cause of pediatric liver disease due to overweight/obesity large-scale epidemics. In clinical practice, diagnosis is usually based on clinical features, blood tests, and liver imaging. Here, we underline the need to make a correct differential diagnosis for a number of genetic, metabolic, gastrointestinal, nutritional, endocrine, muscular, and systemic disorders, and for iatrogenic/viral/autoimmune hepatitis as well. Read More

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December 2018

Gender- and Age-Related Changes in Trunk Muscle Composition Using Chemical Shift Encoding-Based Water⁻Fat MRI.

Nutrients 2018 Dec 13;10(12). Epub 2018 Dec 13.

Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technical University of Munich, Ismaninger Str. 22, 81675 Munich, Germany.

Ageing, sarcopenia, and malnutrition are associated with quantitative and qualitative changes of body composition. There are several imaging modalities, including magnetic resonance imaging (MRI), for the assessment of trunk muscle tissue composition. In this study, we investigated the gender- and age-related changes in trunk muscle composition using chemical shift encoding-based water⁻fat MRI. Read More

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December 2018

Overview on the Effects of -Acetylcysteine in Neurodegenerative Diseases.

Molecules 2018 Dec 13;23(12). Epub 2018 Dec 13.

IRCCS Centro Neurolesi "Bonino-Pulejo", Via Provinciale Palermo, Contrada Casazza, 98124 Messina, Italy.

-acetylcysteine (NAC), which is an acetylated cysteine compound, has aroused scientific interest for decades due to its important medical applications. It also represents a nutritional supplement in the human diet. NAC is a glutathione precursor and shows antioxidant and anti-inflammatory activities. Read More

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December 2018

Impact of Rearing Conditions on the Ambrosia Beetle's Microbiome.

Life (Basel) 2018 Dec 13;8(4). Epub 2018 Dec 13.

Red de Estudios Moleculares Avanzados, Instituto de Ecología A. C., Xalapa C.P. 91070, Mexico.

Ambrosia beetles, along with termites and leafcutter ants, are the only fungus-farming lineages within the tree of life. Bacteria harbored by ambrosia beetles may play an essential role in the nutritional symbiotic interactions with their associated fungi; however, little is known about the impact of rearing conditions on the microbiota of ambrosia beetles. We have used culture-independent methods to explore the effect of rearing conditions on the microbiome associated with , , and , evaluating different media in laboratory-controlled conditions and comparing wild and laboratory conditions. Read More

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December 2018

Ethnobotanic, phytochemical uses and ethnopharmacological profile of genus Cnidoscolus spp. (Euphorbiaceae): A comprehensive overview.

Biomed Pharmacother 2019 Jan 20;109:1670-1679. Epub 2018 Nov 20.

Northeast Biotechnology Network, Graduate Program of Biotechnology, State University of Ceará, Itaperi campus, 60714-903, Fortaleza, CE, Brazil; Biotechnology and Molecular Biology Laboratory, State University of Ceará, Itaperi campus, 60714-903, Fortaleza, CE, Brazil.

The application of medicinal plants are the most important biotechnological alternative in the treatment of numerous diseases, especially in developing countries, such as Brazil. Among them, we specified some specimens of the genus Cnidoscolus used as phytotherapies, with healing properties, analgesic, anti-inflammatory, antibiotic and diuretic, anticancer, among others. Such effects are possibly associated with the presence of terpenoids, alkaloids, coumarins, flavonoids phenolic compounds, among others. Read More

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January 2019

Retinol palmitate and ascorbic acid: Role in oncological prevention and therapy.

Biomed Pharmacother 2019 Jan 13;109:1394-1405. Epub 2018 Nov 13.

Faculty of Pharmacy, Ton Duc Thang University, Ho Chi Minh City-700000, Vietnam; Department of Biological Sciences, Federal University of Piauí, Picos, Piauí, 64.067-670, Brazil. Electronic address:

Cancer development has been directly related to oxidative stress. During chemotherapy, some cancer patients use dietary antioxidants to avoid nutritional deficiencies due to cancer treatment. Among the antioxidants consumed, there are vitamins, including retinyl palmitate (PR) and ascorbic acid (AA), which have the capacity to reduce free radicals formation, protect cellular structures and maintain the cellular homeostasis. Read More

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January 2019

Chronic fatigue syndrome (CFS): Suggestions for a nutritional treatment in the therapeutic approach.

Biomed Pharmacother 2019 Jan 5;109:1000-1007. Epub 2018 Nov 5.

Research Department, Innlandet Hospital Trust, Brumunddal, Norway; Inland Norway University of Applied Sciences, Elverum, Norway.

Chronic fatigue syndrome (CFS) is known as a multi-systemic and complex illness, which induces fatigue and long-term disability in educational, occupational, social, or personal activities. The diagnosis of this disease is difficult, due to lacking a proper and suited diagnostic laboratory test, besides to its multifaceted symptoms. Numerous factors, including environmental and immunological issues, and a large spectrum of CFS symptoms, have recently been reported. Read More

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January 2019

Limitations to using phloem sap to assess tree water and nutrient status.

Tree Physiol 2018 Dec 14. Epub 2018 Dec 14.

School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney NSW, Australia.

Rapid, reliable tools are needed to infer physiological and nutritional health for managing forest systems. Understanding the processes governing tree health is central to the development of these tools. Non-foliar approaches such as the collection of phloem sap reflect processes governing both the use and acquisition of plant water and nutrients at a wide range of temporal (diurnal to seasonal) and spatial (canopy) scales. Read More

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December 2018

Bacteriome-associated Wolbachia of the parthenogenetic termite Cavitermes tuberosus.

FEMS Microbiol Ecol 2018 Dec 14. Epub 2018 Dec 14.

Evolutionary Biology & Ecology, Université libre de Bruxelles, Avenue F.D. Roosevelt 50, CP 160/12, B-1050 Brussels, Belgium.

Wolbachia has deeply shaped the ecology and evolution of many arthropods, and interactions between the two partners are a continuum ranging from parasitism to mutualism. Non-dispersing queens of the termite Cavitermes tuberosus are parthenogenetically produced through gamete duplication, a mode of ploidy restoration generally induced by Wolbachia. These queens display a bacteriome-like structure in the anterior part of the mesenteron. Read More

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December 2018

Prevalence and correlates of anemia among adolescents in Nepal: Findings from a nationally representative cross-sectional survey.

PLoS One 2018 14;13(12):e0208878. Epub 2018 Dec 14.

Department of Paediatrics, the University of Melbourne, Melbourne, Australia.

Anemia is regarded as major public health problem among adolescents in Low and Middle-Income Countries (LMICs) but there is limited primary data in many countries, including Nepal. This study investigated the prevalence and correlates of anemia in a nationally representative sample of adolescents within the 2014 National Adolescent Nutrition Survey in Nepal. A total of 3780 adolescents aged 10 to 19 years were selected from a cross-sectional survey through multi-stage cluster sampling. Read More

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December 2018

Why do current strategies for optimal nutritional therapy neglect the microbiome?

Nutrition 2018 Oct 5;60:100-105. Epub 2018 Oct 5.

Department of Surgery, Oregon Health Sciences University, Portland, Oregon, USA.

Strategies for providing optimal nutritional therapy have evolved over time, with the emphasis on specific directives (such as route, use of immunonutrition, high protein, organ-specific formulas, etc.), achieving variable degrees of success for improving outcomes in the intensive care unit. As the largest immune organ in the body comprising the largest interface between the host and the external environment, the gut can have an amplifying effect on a pattern of dysbiosis, immune dysregulation, and multiple organ failure seen in the critically ill patient. Read More

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October 2018
6 Reads

Normal axillary thickness thresholds as a metric for nutritional status of children.

Clin Imaging 2018 Dec 1;54:57-62. Epub 2018 Dec 1.

Department of Radiology, University of Michigan Medical School, 3208C Medical Sciences Building 1, B1D502, Ann Arbor, MI 48109-5030, United States of America. Electronic address:

Introduction: Childhood pneumonia is a major cause of death in the 3rd world, and undernourishment increases the severity of the condition. We considered axillary thickness as a simple measurement to evaluate nutritional status that can be performed simultaneously with lung ultrasound. Our goal was to determine the distribution of axillary thickness in a cohort of children to determine a threshold for malnutrition. Read More

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December 2018
1 Read

Neutrophils Restrict Tumor-Associated Microbiota to Reduce Growth and Invasion of Colon Tumors in Mice.

Gastroenterology 2018 Dec 11. Epub 2018 Dec 11.

Molecular & Integrative Physiology, University of Michigan School of Public Health, Ann Arbor MI; Internal Medicine Division of Gastroenterology, University of Michigan School of Public Health, Ann Arbor MI; Rogel Cancer Center. University of Michigan Medical School, Ann Arbor MI. Electronic address:

Background & Aims: Neutrophils are among the most prevalent immune cells in the microenvironment of colon tumors, are believed to promote growth of colon tumors, and their numbers correlate with outcomes of patients with colon cancer. Trials of inhibitors of neutrophil trafficking are under way in patients with cancer, but it is not clear how neutrophils contribute to colon tumorigenesis.

Methods: Colitis-associated colon cancer was induced mice with conditional deletion of neutrophils (LysMCre;Mcl1) and wild-type littermates (LysMCre;Mcl1, control mice) by administration of azoxythmethane and/or dextran sulfate sodium. Read More

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December 2018

Vitamin B12 and folate deficiencies are not associated with nutritional or weight status in older adults.

Exp Gerontol 2018 Dec 11. Epub 2018 Dec 11.

Unit for Aging Brain and Dementia, Department of Geriatric Medicine, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.

It is not known whether undernutrition causes vitamin B12 and folate deficiencies. The present study aimed to determine whether nutritional status, measured using the Mini Nutritional Assessment (MNA) scale, and body mass index (BMI) are indicators of lower level serum vitamin B12 and folate in older adults. 1007 outpatients aged 65 years or over were included the study. Read More

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December 2018

Nutritional risk index as a predictor of mortality in acutely decompensated heart failure.

PLoS One 2018 14;13(12):e0209088. Epub 2018 Dec 14.

Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea.

Background: We investigated the role of nutritional risk index (NRI) in predicting 1-year mortality in patients with acute decompensated heart failure (ADHF).

Methods: Among 5,625 cohort patients enrolled in Korean Acute Heart Failure (KorAHF) Registry, a total of 5,265 patients who were possible to calculate NRI [NRI = (1.519 x serum albumin [g/dl]) + (41. Read More

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December 2018
1 Read

Impact of a Nutrition-Focused Quality Improvement Intervention on Hospital Length of Stay.

J Nurs Care Qual 2018 Dec 12. Epub 2018 Dec 12.

Clinical Nutrition, Sodexo Healthcare, Gaithersburg, Maryland (Ms Siegel and Mr Higgins); Department of Agricultural Economics, Mississippi State University, Starkville, Mississippi (Dr Fan); Catholic Heath Initiatives, Denver, Colorado (Ms Goldman); and Health Economics and Outcomes Research, Abbott Nutrition Research and Development, Columbus, Ohio (Drs Goates and Partridge).

Background: Despite its high prevalence, malnutrition in hospitalized patients often goes unrecognized and undertreated.

Local Problem: A hospital system sought to improve nutrition care by implementing a quality improvement initiative. Nurses screened patients upon admission using the Malnutrition Screening Tool and initiated oral nutrition supplements for patients at risk. Read More

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December 2018

Effects of apolipoprotein E on nutritional metabolism in dementia.

Curr Opin Lipidol 2018 Dec 12. Epub 2018 Dec 12.

Geriatric Research, Education, and Clinical Center, Veterans Affairs Puget Sound Healthcare System.

Purpose Of Review: Various groups have explored the effect of apolipoprotein E (APOE) on neurodegeneration through nutritional and metabolic alterations. In this review, we hope to summarize recent findings in humans as well as preclinical APOE models.

Recent Findings: Metabolic pathways including lipid metabolism appear to play a large role in the pathophysiology of Alzheimer's disease. Read More

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December 2018

Losartan prevents the elevation of blood pressure in adipose-PRR deficient female mice while elevated circulating sPRR activates the renin angiotensin system.

Am J Physiol Heart Circ Physiol 2018 Dec 14. Epub 2018 Dec 14.

Graduate Center for Nutritional Sciences, University of Kentucky, United States.

The deletion of the prorenin receptor (PRR) in adipose tissue elevates systolic blood pressure (SBP) and circulating soluble form of PRR (sPRR) in male mice fed a high-fat diet (HF). However, sex differences in the contribution of adipose-PRR and sPRR to the regulation of the renin-angiotensin system (RAS) in key organs for blood pressure control are undefined. Therefore, we assessed blood pressure and the systemic and intrarenal RAS status in adipose-PRR KO female mice. Read More

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December 2018
1 Read

Functional, nutritional and social factors associated with mobility limitations in the elderly: a systematic review.

Salud Publica Mex 2018 Sep-Oct;60(5):579-585

Postgraduate Program in Collective Health, Odontology Department, Federal University of Rio Grande do Norte. Natal, Brazil.

Objective: To systematically review the prevalence and incidence of mobility limitations in the elderly people and their associated factors.

Materials And Methods: Articles in the electronic literature were searched via PubMed, Scopus,,Lilacs, SciELO, PAHO, MedCarib, Repidisca, Wholis, IBCES, PEDro, Medline and Bireme (2012-2016). The instrument STROBE was used to analyze the quality of the work and the PRISMA recommendation was used to structure the review. Read More

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September 2017

An overview of inflammatory bowel disease.

Authors:
Lisa Younge

Nurs Stand 2018 Dec 10. Epub 2018 Dec 10.

The Royal London Hospital, London, England.

Inflammatory bowel disease (IBD) is a term that refers to two main conditions: Crohn's disease and ulcerative colitis. It is a lifelong inflammatory disorder that affects the gastrointestinal tract. Managing IBD requires a multidisciplinary team approach, and specialist IBD nurses have an important role in this, providing education, support and advocacy to patients with IBD. Read More

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December 2018
1 Read

[FSGS collapsing variant during anabolic steroid abuse: Case Report].

G Ital Nefrol 2018 Dec;35(6)

UO Nefrologia e Dialisi AUSL Romagna Ospedale Infermi Rimini.

Anabolic Androgenic Steroids (AAS) is an hormone family whose use has considerably increased among body-builders during the last decades. The AAS abuse, especially associated with other drugs or nutritional supplements and protein loads, may cause a variety of pathologies to several organs with a mechanism related to dosage, timing and substance. The kidney is the main metabolizer of these drugs and it can be acutely or chronically damaged with ESKD. Read More

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December 2018

Changes in Prealbumin and Body Mass Index Associated with T Lymphocyte Subsets and Nutritional Status in Chronic Hepatitis B and HBV-Cirrhosis Patients.

Clin Lab 2018 Oct;64(11)

Background: Patient immune response is one of the main factors influencing hepatitis virus (HBV) eradication or chronicity. Our study aimed to investigate the relationship between the nutritional status and immune function, and to provide the appropriate clinical diagnosis data for treatment of patients with chronic hepatitis B virus (CHB) and cirrhosis. Methods: T lymphocyte subsets were tested using flow cytometry in 100 patients (48 with CHB, 52 with cirrhosis) and 26 healthy individuals. Read More

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October 2018

Integrating a genome-wide association study with a large-scale transcriptome analysis to predict genetic regions influencing the glycaemic index and texture in rice.

Plant Biotechnol J 2018 Dec 13. Epub 2018 Dec 13.

International Rice Research Institute, Los Baños, Laguna, 4030, Philippines.

Reliably generating rice varieties with low glycaemic index (GI) is an important nutritional intervention given the high rates of Type II diabetes incidences in Asia where rice is staple diet. We integrated a genome-wide association study (GWAS) with a transcriptome-wide association study (TWAS) to determine the genetic basis of the GI in rice. GWAS utilized 305 re-sequenced diverse indica panel comprising ~2. Read More

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December 2018

Developmental regulation of lifelong dental experiences and beliefs in Guangzhou and Hong Kong.

Gerodontology 2018 Dec 14. Epub 2018 Dec 14.

Cooperative Research Centre for Oral Health Science Melbourne Dental School, University of Melbourne, Melbourne, Victoria, Australia.

Aims: The aim of this study was to explain through the life-course and life-span perspectives of developmental regulation theory the controls on dental experiences and beliefs throughout the lives of older people in Guangzhou and Hong Kong.

Background: Dental diseases and disabilities among older people are serious public health concerns in China.

Methods: A facilitator conducted eight focus groups, three in Hong Kong and five in Guangzhou, involving a total of 51 participants. Read More

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December 2018
0.806 Impact Factor

Do lifestyle interventions during pregnancy have the potential to reduce long-term postpartum weight retention? A systematic review and meta-analysis.

Obes Rev 2018 Dec 12. Epub 2018 Dec 12.

Else Kroener-Fresenius Center for Nutritional Medicine, University Hospital Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

Reducing postpartum weight retention is a promising strategy for addressing the rising prevalence of overweight and obesity in women. This systematic review and meta-analysis explored whether lifestyle interventions during pregnancy have the potential to reduce weight retention at 4 months postpartum and beyond. A search of five electronic databases for randomized controlled trials comparing the effect of weight-related lifestyle interventions beginning in pregnancy on postpartum weight retention to standard prenatal care groups was performed. Read More

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December 2018

Are overweight people more susceptible to anxiety?

Int J Geriatr Psychiatry 2018 Dec 12. Epub 2018 Dec 12.

Center for Tobacco Control Research, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

Objectives: This study aimed to investigate anxiety status and its relationship with BMI among empty nesters in China, so as to improve their quality of life and provide direction for further research.

Methods: A cross-sectional survey was conducted among 4901 empty nesters in Shanxi, China. Anxiety, weight, height, depression, socio-demographic variables, attention to daily nutritional health, social activities, and self-care ability were evaluated in the study. Read More

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December 2018

Association Between Muscle Strength and Modeling Estimates of Muscle Tissue Heterogeneity in Young and Old Adults.

J Ultrasound Med 2018 Dec 12. Epub 2018 Dec 12.

Research Service, Washington, DC, USA.

Objectives: Assessing aging muscle through estimates of muscle heterogeneity may overcome some of the limitations of grayscale analyses. The objectives of this study included determining statistical model parameters that characterize muscle echogenicity and are associated with strength in younger and older participants.

Methods: Thirty-three community-dwelling participants were assigned to younger and older groups. Read More

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December 2018

Enzymatic Assisted Development of Biofunctional Polyphenol-enriched Buckwheat Protein: Physicochemical Property, In Vitro Digestibility and Antioxidant Activity.

J Sci Food Agric 2018 Dec 12. Epub 2018 Dec 12.

Food Protein Research and Development Center, Department of Food Science and Engineering, South China University of Technology, Guangzhou, 510640, PR China.

Background: During the last decade, buckwheat is reported to have biological activities and functional properties. The present study investigated the high-polyphenol buckwheat (Fagopyrum esculentum Moench) protein prepared by dual-enzymatic hydrolysis assisting and its physicochemical property, in vitro digestibility and antioxidant activity.

Results: Results showed that the polyphenols of the buckwheat protein (E-BWP) from a synergistic enzymatic action of 1. Read More

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December 2018

Doubled lifespan and patient-like pathologies in progeria mice fed high-fat diet.

Aging Cell 2018 Dec 12:e12852. Epub 2018 Dec 12.

Edward A. Doisy Department of Biochemistry and Molecular Biology, St Louis University School of Medicine, St Louis, Missouri.

Hutchinson-Gilford Progeria Syndrome (HGPS) is a devastating premature aging disease. Mouse models have been instrumental for understanding HGPS mechanisms and for testing therapies, which to date have had only marginal benefits in mice and patients. Barriers to developing effective therapies include the unknown etiology of progeria mice early death, seemingly unrelated to the reported atherosclerosis contributing to HGPS patient mortality, and mice not recapitulating the severity of human disease. Read More

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December 2018
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Health outcomes in spinal muscular atrophy type 1 following AVXS-101 gene replacement therapy.

Pediatr Pulmonol 2018 Dec 12. Epub 2018 Dec 12.

Department of Pediatrics, Ohio State University, Columbus, Ohio.

Background: Spinal Muscular Atrophy type 1 (SMA1) is a rare genetic neuromuscular disease where 75% of SMA1 patients die/require permanent-ventilation by 13.6 months. This study assessed the health outcomes of SMA1 infants treated with AVXS-101 gene replacement therapy. Read More

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December 2018
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Chemical and isotopic markers detect water deficit and its influence on nutrient allocation in P. vulgaris.

Physiol Plant 2018 Dec 11. Epub 2018 Dec 11.

Sydney Institute of Agriculture, School of Life and Environmental Sciences, Faculty of Science, The University of Sydney, Sydney, NSW, 2006, Australia.

The impact of drought on plant growth and yield has been widely studied and is considered a major limitation to crops reaching yield potential. Less known is the impact of water deficit on the nutritional quality of the resulting yield. This study characterised the impact of water deficit on carbon assimilation, modelled water use efficiency from carbon isotope discrimination and analysed the concentration of mineral nutrients, amino acids and sugars in leaf, phloem and pod pools collected from Phaseolus vulgaris L. Read More

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December 2018

Interaction of body mass index or waist-to-hip ratio and sun exposure associated with nonmelanoma skin cancer: A prospective study from the Women's Health Initiative.

Cancer 2018 Dec 11. Epub 2018 Dec 11.

Division of Dermatology, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California.

Background: The incidence of nonmelanoma skin cancer (NMSC) exceeds the incidence of all other types of cancers combined. Cumulative sun exposure and intermittent sun exposure are known risk factors for the development of NMSC. Because obesity has been shown to decrease the risk of NMSC incidence, this study investigated whether the risk of NMSC with sun exposure was consistent across different levels of body size. Read More

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December 2018