3,308 results match your criteria Nutrition and Cancer[Journal]


An Analysis of Overweight and Obesity Status among Childhood Cancer Survivors in Saudi Arabia: A Single Center Study.

Nutr Cancer 2019 Feb 22:1-7. Epub 2019 Feb 22.

e Clinical Oncology Department, Faculty of Medicine , Mansoura University , Mansoura , Egypt.

Overweight and obesity in the pediatric population remains a growing worldwide health burden. The extent to which this trend extends to childhood cancer survivors (CCS) remains less well explored. We conducted a retrospective observational study from a single institution in Saudi Arabia to estimate the prevalence of overweight and obese status among CCS over a five-year period. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2019.1577980DOI Listing
February 2019

Prognostic Nutritional Index Predicts Outcomes of Patients after Gastrectomy for Cancer: A Systematic Review and Meta-Analysis of Nonrandomized Studies.

Nutr Cancer 2019 Feb 22:1-12. Epub 2019 Feb 22.

a Department of General Surgery , The Third Hospital of Mianyang the Mental Health Center of Sichuan , Mianyang , Sichuan , China.

Objective: The primary aim of this systematic review was to evaluate the survival predication value of preoperative prognostic nutritional index (PNI) in patients with gastric cancer. The second aim was to explore the relationship between preoperative PNI and clinicopathological features.

Methods: A systematic search of the electronic databases identified studies that investigated the association of preoperative PNI with short or long-term outcomes among patients after gastrectomy for cancer. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2019.1577986DOI Listing
February 2019

Induction of Apoptosis in HeLa by Corn Small RNAs.

Nutr Cancer 2019 Feb 20:1-11. Epub 2019 Feb 20.

a Cancer and Translational Research Lab, Dr D. Y. Patil Biotechnology & Bioinformatics Institute, Dr D.Y. Patil Vidyapeeth , Pune , India.

Insights in RNA biology have opened up a plethora of opportunities to explore the small regulatory RNAs from various natural and artificial sources. These small RNAs have been suggested to play a role too in tumor progression by either as oncogenic or tumor suppressor small RNAs. In this study, authors have attempted to evaluate the therapeutic potential of small RNAs fractionated from corn (Zea mays) upon growth and survival of HeLa. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/01635581.2018.1
Publisher Site
http://dx.doi.org/10.1080/01635581.2018.1526307DOI Listing
February 2019
1 Read

A Step toward Understanding Diet Quality in Urban African-American Breast Cancer Survivors: A Cross-sectional Analysis of Baseline Data from the Moving Forward Study.

Nutr Cancer 2019 Feb 18:1-16. Epub 2019 Feb 18.

e Department of Medicine , Medical College of Wisconsin , Milwaukee , Wisconsin , USA.

Purpose: Little is known about the dietary behaviors of African-American breast cancer survivors (AABCS). We sought to describe dietary intake and quality in AABCS and examine associations with demographic, social, lifestyle, and body composition factors to potentially inform the development of effective dietary interventions.

Methods: Baseline data from a prospective weight loss trial of 210 AABCS were assessed. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1557217DOI Listing
February 2019

Sea Squirt (Halocynthia roretzi) Hydrolysates Induce Apoptosis in Human Colon Cancer HT-29 Cells through Activation of Reactive Oxygen Species.

Nutr Cancer 2019 Feb 9:1-10. Epub 2019 Feb 9.

a Department of Marine-Bio Convergence Science , Pukyong National University , Busan , Republic of Korea.

Recent evidence provides that seafood has a lot of health benefits due to its unique bioactive compounds. Sea squirt is widely cultured and consumed as a foodstuff in Korea; however, seldom reports with reference to bioactivities are available until now. In this study, edible part of sea squirt was hydrolyzed by pepsin and its hydrolysates was evaluated for anticancer effect on human colon cancer HT-29 cells. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1540717DOI Listing
February 2019

Pre-Operative vs. Peri-Operative Nutrition Supplementation in Hepatic Resection for Cancer: A Systematic Review.

Nutr Cancer 2019 Feb 9:1-20. Epub 2019 Feb 9.

c Discipline of Surgery, School of Medicine , University of Sydney , Camperdown , NSW , Australia.

Despite improvements in safety of hepatic resection post-operative complications occur in up to a half of patients. A systematic review was undertaken to compare the effect of pre-operative and peri-operative nutritional supplementation on post-operative outcomes in patients undergoing hepatic resection for malignancy. Included studies were identified through a search of PubMed (1966 to November 2016), Embase (1947 to November 2016) and the Cochrane Library (1993 to November 2016). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1560479DOI Listing
February 2019

Nutrition and Cancercapsaicin Treatment Reduces Tumor Growth, Tumor Cell Proliferation Ex Vivo and Partially Reverses Cancer Cachexia in Walker 256 Tumor-Bearing Rats.

Nutr Cancer 2019 Feb 9:1-7. Epub 2019 Feb 9.

d Departamento de Patologia Médica , Hospital das Clínicas, Universidade Federal do Paraná , Curitiba , Brazil.

Capsaicin (trans-8-methyl-n-vanillyl-6-nonenamide) is the main pungent component found in hot peppers.

Aim: In this study, we investigated the effect of capsaicin treatment on tumor growth and the metabolic indicators of cachexia in Walker 256 tumor-bearing rats.

Methods: Male Wistar rats were inoculated subcutaneously in the right flank with 1 ml of a sterile suspension of 3 × 10 Walker tumor cells. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1557219DOI Listing
February 2019

Encapsulation of Nutraceutical Ingredients in Liposomes and Their Potential for Cancer Treatment.

Nutr Cancer 2019 Feb 9:1-15. Epub 2019 Feb 9.

a Computational Modeling and Nano Scale Processing Unit , Indian Institute of Food Processing Technology (IIFPT), Ministry of Food Processing Industries, Government of India , Thanjavur , Tamil Nadu, India.

At present, cancer is one of the major diseases in the world affecting numerous lives. There have been various approaches to combat the disease, particularly involving chemical interventions (chemotherapy). However, owing to serious side effects of chemotherapy, employment of natural supplements in cancer therapy has been long desired. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1557212DOI Listing
February 2019

Nutritional Risk Assessment by Scored Patient-Generated Subjective Global Assessment Associated with Demographic Characteristics in 23,904 Common Malignant Tumors Patients.

Nutr Cancer 2019 Feb 9:1-11. Epub 2019 Feb 9.

k Department of Gastrointestinal Surgery/Clinical Nutrition , Beijing Shijitan Hospital, Capital Medical University , Beijing , PR China.

Malnutrition is a problem affecting tumor patients greatly. This study aims to investigate whether demographic characteristics are related to the malnutrition of cancer patients. Twenty-three thousand nine hundred and four (23,904) patients with 16 common malignant tumors were enrolled in the study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2019.1566478DOI Listing
February 2019
2.322 Impact Factor

Body Composition Adjusted Dosing of Gemcitabine-Nab-Paclitaxel in Pancreatic Cancer Does Not Predict Toxicity Compared to Body Surface Area Dosing.

Nutr Cancer 2019 Feb 9:1-5. Epub 2019 Feb 9.

f School of Clinical Sciences , Monash University , Clayton , Victoria , Australia.

Combination gemcitabine and nab-paclitaxel (Gem-Nab-P) is a common regimen used to treat metastatic pancreatic ductal adenocarcinoma (PDAC). Toxicity from this regimen is associated with significant morbidity. Currently, Gem-Nab-P is dosed using estimated body surface area, derived from height and weight. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1542011DOI Listing
February 2019
3 Reads
2.322 Impact Factor

Nutritional Interventions for Treating Cancer-Related Fatigue: A Qualitative Review.

Nutr Cancer 2019 Jan 26:1-20. Epub 2019 Jan 26.

a Department of Surgery , University of Rochester Medical Center (URMC) , Rochester , New York , USA.

Cancer-related fatigue (CRF) is a debilitating syndrome that persists for many cancer survivors for years after treatment. Symptoms include early and persistent fatigue, functional decline, depression, and cognitive difficulties. Inflammation, assessed using pro-inflammatory biomarkers, is increased in cancer survivors with fatigue and treatments for fatigue are often aimed at reducing inflammation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1513046DOI Listing
January 2019
2 Reads

Low Phase Angle Is Correlated With Worse General Condition in Patients with Advanced Cancer.

Nutr Cancer 2019 Jan 26:1-6. Epub 2019 Jan 26.

g Palliative and Supportive Care Division , Seirei Mikatahara Hospital , Hamamatsu , Japan.

Objectives: Phase angle (PA) is a poor prognostic factor in patients with advanced cancer. This study aimed to identify possible correlations between PA and symptoms, quality of life, fluid retention, and laboratory data in cancer patients in palliative care settings.

Methods: Individuals who visited the outpatient clinic or were admitted to the palliative care unit were eligible. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1557216DOI Listing
January 2019

Emerging Roles of Probiotics in Prevention and Treatment of Breast Cancer: A Comprehensive Review of Their Therapeutic Potential.

Nutr Cancer 2019 Jan 26:1-12. Epub 2019 Jan 26.

d Department of Traditional Pharmacy, School of Persian Medicine , Tehran University of Medical Sciences , Tehran , Iran.

Breast cancer is the most common cancer among women. Need for novel preventive and curative approaches with more safety than the present one seems inevitable. This review is devoted to potentially favorable role of probiotics in prevention and treatment of breast cancer as well as their alleviating role regarding chemotherapy-induced side effects. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1557221DOI Listing
January 2019

Platinum Combination Chemotherapy Is Poorly Tolerated in Malnourished Advanced Lung Cancer Patients with Poor Performance Status.

Nutr Cancer 2019 Jan 26:1-5. Epub 2019 Jan 26.

a Division of Thoracic Oncology , Shizuoka Cancer Center , Shizuoka , Japan.

This study aimed to explore the tolerability and safety of platinum combination chemotherapy in malnourished patients with advanced non-small cell lung cancer (NSCLC) and poor performance status (PS). We retrospectively reviewed NSCLC patients with a PS of 2 who received first-line platinum combination chemotherapy at the Shizuoka Cancer Center between December 2009 and December 2014. Nutritional status was classified using the Glasgow Prognostic Score (GPS), which is an indicator of systemic inflammation and malnutrition. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1559941DOI Listing
January 2019

The Impact of Preoperative Underweight Status on Postoperative Complication and Survival Outcome of Gastric Cancer Patients: A Systematic Review and Meta-analysis.

Nutr Cancer 2019 Jan 26:1-10. Epub 2019 Jan 26.

a Department of Surgical Oncology , First Affiliated Hospital of China Medical University , Heping District , Shenyang , People's Republic of China.

Objective: In this study, we performed a systematic review and meta-analysis to evaluate the impact of preoperative underweight status on postoperative complications and survival outcome of gastric cancer (GC) patients.

Methods: The related studies were identified by searching PubMed and Embase databases. According to the body mass index (BMI), all patients were classified into underweight group (<18. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1559937DOI Listing
January 2019
1 Read

Consumption of Decorticated Pulses Ensures the Optimum Intake of Isoflavones by the Urban Indian Population.

Nutr Cancer 2019 Jan 26:1-11. Epub 2019 Jan 26.

a Food Engineering and Technology Department , Institute of Chemical Technology , Mumbai , India.

Sample urban population was assessed for consumption of legumes. Genistein and daidzein content of commonly consumed legumes was evaluated to estimate the isoflavone intake through the consumption of these legumes by selected population. Total genistein content of all legumes considered for analysis was found to be in the range of 0. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1559936DOI Listing
January 2019

MIX2: A Novel Natural Multi-Component Modulator of Multidrug-Resistance and Hallmarks of Cancer Cells.

Nutr Cancer 2019 Jan 24:1-14. Epub 2019 Jan 24.

a Department of Biochemistry and Molecular Biology , Centre of Postgraduate Medical Education , Warsaw , Poland.

Multidrug resistance is one of the key barriers suppressing the effectiveness of drug therapies of malignant tumors. Here, we report a study on the effect of a mix of natural extracts (MIX2) prepared from fresh fruits of Prunus spinosa, Crataegus monogyna, Sorbus aucuparia, and Euonymus europaeus on the classic hallmarks of cancer cells and the expression of multidrug resistance proteins. In the studies, HeLa and T98G cell lines, and classic methods of molecular biology, including RT-qPCR, Western blot, flow cytometry, and confocal imaging, were used. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/01635581.2018.1
Publisher Site
http://dx.doi.org/10.1080/01635581.2018.1560480DOI Listing
January 2019
6 Reads

Vitamin C Prevents Hydrocortisone-Induced Injury in HMEC-1 through Promoting Bestrophin-3 Expression.

Nutr Cancer 2019 Jan 23:1-9. Epub 2019 Jan 23.

b Department of Orthopedics , The First Hospital of Hebei Medical University , Shijiazhuang , PR China.

Objective: To investigate the protective effects and underlying mechanisms of Vitamin C (VC) on hydrocortisone (HC)-induced cell injury in human microvascular endothelial cells (HMEC).

Methods: Cell viability was measured by CCK-8 assay and the expression of Best-3 was detected by Western blotting assay. The experiment was divided into normal control, HC injury group, VC treatment groups, HC + Best-3 siRNA group, HC + VC + Best-3 siRNA group, HC + pcDNA3. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1539184DOI Listing
January 2019
7 Reads

Investigation of TF-binding lectins from dietary sources and SRL on proliferation and cell cycle progression in human colon HT29 and SW620 cells.

Nutr Cancer 2019 Jan 23:1-9. Epub 2019 Jan 23.

a Department of Studies in Biochemistry , Karnatak University , Dharwad , India;

TF antigen binding lectins from dietary sources PNA, ACA, ABL, JAC, and SRL from Sclerotium rolfsii have been reported to induce diverse effects on cancer cell proliferation by different mechanisms. This study aimed to compare effects of these lectins on growth and cell cycle progression in colon cancer HT29 and SW620 cells. As reported SRL, ABL, and JAC inhibited while PNA and ACA increased cell proliferation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1559940DOI Listing
January 2019

Relationship between Sarcopenia and mTOR Pathway in Patients with Colorectal Cancer: Preliminary Report.

Nutr Cancer 2019 Jan 20:1-6. Epub 2019 Jan 20.

a Universidade Federal de Minas Gerais , Belo Horizonte , Brazil.

Sarcopenia is a syndrome characterized by loss of muscle mass and strength that impacts clinical outcomes and mortality in cancer patients. Although the molecular pathways involved in sarcopenia are not fully elucidated, the decrease in protein synthesis rate appears to be one of the most important events. The objective of this study was to investigate the relationship between sarcopenia and mTOR signaling pathway in patients undergoing colorectal resection surgery. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1540716DOI Listing
January 2019
2 Reads

Pre-Exposure to Chronic Unpredictable Stress Suppresses the Chemopreventive Potential of Aloe Vera (Av) Leaf Gel Against 7,12-Dimethylbenz(a)anthracene (DMBA) Induced Carcinogenesis.

Nutr Cancer 2019 Jan 20:1-13. Epub 2019 Jan 20.

a Department of Biochemistry, Faculty of Life Sciences , Aligarh Muslim University (AMU) , Aligarh , Uttar Pradesh , India.

The present study evaluates the topical application of aloe vera (Av) leaf gel as a protective natural product against 7,12-dimethylbenz(a)anthracene (DMBA)-induced skin lesions in Swiss albino mice and as an antioxidant for the systemic toxicity of DMBA in the presence and absence of chronic unpredictable stress (CUS). Animals were randomized into seven groups and sacrificed after 16 weeks of treatment. Av gel application along with DMBA + 12-O-tetradecanoylphorbol-13-acetate (TPA) was found to be effective in reducing tumor incidence, cumulative number of papillomas, tumor burden and tumor yield when compared to untreated groups. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1560482DOI Listing
January 2019
1 Read

Isochamanetin is a Selective Inhibitor for CyclinD1 in SKOV3 Cell Lines.

Nutr Cancer 2019 Jan 19:1-11. Epub 2019 Jan 19.

a Department of Biotechnology , Sathyabama Institute of Science and Technology , Chennai , India.

The cyclinD1 is an emerging potent therapeutic drug target in the treatment of ovarian cancer. CyclinD1, Cdks phosphorylation regulates cell cycle and controls transcription. For this reason, CyclinD1 have been subject to extensive cell cycle- related research, and consequently various therapeutic inhibitor drugs have been developed to these protein targets. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1559933DOI Listing
January 2019
2 Reads

Phyla nodiflora L. Extracts Induce Apoptosis and Cell Cycle Arrest in Human Breast Cancer Cell Line, MCF-7.

Nutr Cancer 2019 Jan 19:1-8. Epub 2019 Jan 19.

a Biotechnology Research Institute, Universiti Malaysia Sabah , Kota Kinabalu , Sabah , Malaysia.

Phyla nodiflora L. has been used as medicinal remedies for various ailments due to its antioxidant, anti-inflammatory, anti-bacterial, anti-tumor activity. Previously, we found that the plant extracts induced DNA fragmentation in MCF-7. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1559942DOI Listing
January 2019
2 Reads

Pretreatment Controlling Nutritional Status Score and Lactate Dehydrogenase as Predictive Markers of Survival in Patients with Malignant Peritoneal Mesothelioma.

Nutr Cancer 2019 Jan 20:1-11. Epub 2019 Jan 20.

a Department of Gastroenterology , Cangzhou Central Hospital , Cangzhou , Hebei , China.

Objective: To investigate the relationships between the Controlling Nutritional Status (CONUT) score and ascites fluid lactate dehydrogenase (LDH) level, and prognosis in patients with malignant peritoneal mesothelioma (MPeM).

Methods: A total of 125 patients with MPeM were selected for the study using a pathological screening method. Once the diagnosis is established, before the treatment their clinical characteristics and nutritional evaluations were recorded including CONUT score and ascites LDH level. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1560481DOI Listing
January 2019
4 Reads

Low Transthyretin Levels Predict Poor Prognosis in Cancer Patients in Palliative Care Settings.

Nutr Cancer 2019 Jan 20:1-7. Epub 2019 Jan 20.

a Department of Palliative Medicine , National Cancer Center Hospital East , Kashiwa , Japan.

Objectives: Although transthyretin (TTR) is a nutritional indicator and is influenced by systemic inflammation, it may be a good prognostic indicator for cancer patients in palliative care settings. This study investigates the correlation between low TTR levels and survival among cancer patients in palliative care settings.

Methods: This was a sub-analysis of a prospective, multicenter cohort study. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1557213DOI Listing
January 2019
4 Reads

TAS2R38 Bitterness Receptor Genetic Variation and Risk of Gastrointestinal Neoplasm: A Meta-Analysis.

Nutr Cancer 2019 Jan 20:1-9. Epub 2019 Jan 20.

a Department of Cancer Biomedical Science Graduate School of Cancer Science and Policy , National Cancer Center , Goyang-si , Gyeonggi-do , Korea.

Genetic variation in TAS2R38 bitterness taste receptor could alter the efficacy of molecular sensing, hence may be associated with cancer risk. Thus, we performed a meta-analysis to verify the association between the risk of gastrointestinal (GI) neoplasm and TAS2R38 genetic variation. Studies with TAS2R38 diplotype distribution and GI neoplasm phenotypes were searched from PubMed, EMBASE and SCOPUS, and five articles including eight studies were finally selected. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/01635581.2018.1
Publisher Site
http://dx.doi.org/10.1080/01635581.2018.1559935DOI Listing
January 2019
4 Reads

The Use of Trace and Essential Elements in Common Clinical Disorders: Roles in Assessment of Health and Oxidative Stress Status.

Nutr Cancer 2019 Jan 19:1-8. Epub 2019 Jan 19.

b Laboratorio de Farmacología, INP and Facultad de Medicina , Universidad Nacional Autónoma de México , Mexico City , Mexico.

During the early life, the diet of infants is mainly dominated by milk. Milk is a natural food rich in trace elements focus on essential elements. These elements are very necessary for human metabolism and since they cannot be synthesized by the body, the only source available for the humans to obtain them is by ingestion of natural food. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1557214DOI Listing
January 2019

Prognostic Role of the Prognostic Nutritional Index in Pancreatic Cancer: A Meta-analysis.

Nutr Cancer 2019 Jan 20:1-7. Epub 2019 Jan 20.

a Department of Radiation Oncology , The First Affiliated Hospital of China Medical University , Shenyang , China.

Objective: The prognostic nutritional index (PNI) has been reported to play an important prognostic role in various malignancies. Here we performed a meta-analysis to explore the predictive value of PNI in pancreatic cancer (PC).

Methods: Clinical studies about PNI and prognosis in PC were retrieved from Pubmed, Embase, Web of Science and Cochrane Libarary updated on 31 December 2017. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1559930DOI Listing
January 2019

Enteral Nutrition Support Does Not Improve PNI in Radiotherapy Patients with Locally Advanced Esophageal Cancer.

Nutr Cancer 2019 Jan 20:1-7. Epub 2019 Jan 20.

a Department of Radiation Oncology , Zhejiang Cancer Hospital , Hangzhou , China.

Objective: The assessment of prognostic nutritional index (PNI) before and during radiotherapy is an important parameter for the prognosis in patients with cancer. In this study, enteral tube feeding (ETF) was used during radiotherapy in patients with EC. Dynamic changes of various nutritional indicators (including PNI) were monitored. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1559939DOI Listing
January 2019
1 Read

Neuroprotective Effect of Ilex Paraguariensis Intake on Brain Myelin of Lung Adenocarcinoma-Bearing Male Balb/c Mice.

Nutr Cancer 2019 Jan 19:1-5. Epub 2019 Jan 19.

a Consejo Nacional de Investigaciones Científicas y Técnicas, CONICET, INICSA , Córdoba , Argentina.

Ilex paraguariensis (IP) is widely consumed as tea with high nutritional value. This plant contains several bioactive phenolic compounds, which are antioxidant and anti-inflammatory. On the other hand, lung adenocarcinoma (LAC) deleteriously involves neoplastic progression, inflammatory paraneoplastic syndromes, and death. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1559932DOI Listing
January 2019
5 Reads

Regulation of the Intracellular ROS Level Is Critical for the Antiproliferative Effect of Quercetin in the Hepatocellular Carcinoma Cell Line HepG2.

Nutr Cancer 2019 Jan 19:1-9. Epub 2019 Jan 19.

a Department of Pharmaceutical Engineering , Hoseo University , Asan , Republic of Korea.

Quercetin, an antioxidant flavonoid, has been known that it can induce the cell cycle arrest and apoptosis of hepatocellular carcinoma (HCC) cells by the stabilization or induction of p53. Here, we found that quercetin reduced the proliferation of HepG2 cells significantly, but not Huh7 cells. Interestingly, quercetin down-regulated the intracellular ROS level in HepG2 cells, but not Huh7 cells. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1559929DOI Listing
January 2019

An Olive Leaf Extract Rich in Polyphenols Promotes Apoptosis in Cervical Cancer Cells by Upregulating p21 Gene Expression.

Nutr Cancer 2019 Jan 19:1-14. Epub 2019 Jan 19.

a Kidney and Transplantation Research Center, Annunziata Hospital , Cosenza , Italy.

Most of the common drugs used to treat the cervical cancer, which main etiological factor is the HPV infection, cause side effects and intrinsic/acquired resistance to chemotherapy. In this study we investigated whether an olive leaf extract (OLE), rich in polyphenols, was able to exert anti-tumor effects in human cervical cancer cells (HeLa). MTT assay results showed a reduction of HeLa cells viability OLE-induced, concomitantly with a gene and protein down-regulation of Cyclin-D1 and an up-regulation of p21, triggering intrinsic apoptosis. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1559934DOI Listing
January 2019
1 Read

Changes in Circulating Levels of 25-hydroxyvitamin D3 in Breast Cancer Patients Receiving Chemotherapy.

Nutr Cancer 2019 Jan 19:1-11. Epub 2019 Jan 19.

a Division of Human Nutrition and Health , Wageningen University & Research , Wageningen , the Netherlands.

Cancer treatments, toxicities and their effects on lifestyle, may impact levels of vitamin D. The aim of this study was to determine serum 25-hydroxyvitamin D3 (25(OH)D) levels before, directly after and 6 months after chemotherapy in breast cancer patients (n = 95), and a comparison group of women (n = 52) not diagnosed with cancer. Changes in 25(OH)D levels over time were compared using linear mixed models adjusted for age and season of blood sampling. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1559938DOI Listing
January 2019
2 Reads

Devil's Club Falcarinol-Type Polyacetylenes Inhibit Pancreatic Cancer Cell Proliferation.

Nutr Cancer 2019 Jan 19:1-11. Epub 2019 Jan 19.

a Department of Surgery , University of British Columbia , Vancouver , British Columbia , Canada.

Natural falcarinol-type (FC-type) polyacetylenes are known to show anticancer activities. We studied the bioactivity of synthetic FC, 1,2-dihydrofalcarinol (FCH) and 3-acetoxyfalcarinol (FCA) and compared them with the natural bioactive polyacetylene [9,17-octadecadiene-12,14-diyne-1,11,16-triol,1-acetate] (DCA) isolated from Devil's club (DC) Oplopanax horridus. Antiproliferation activity of these polyacetylenes, along with DC inner stem bark 70% ethanol and water extracts, was tested on human pancreatic ductal adenocarcinoma cell lines PANC-1 and BxPC-3. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1559931DOI Listing
January 2019
1 Read

Zerumbone Suppresses Human Colorectal Cancer Invasion and Metastasis via Modulation of FAk/PI3k/NFκB-uPA Pathway.

Nutr Cancer 2019 Jan 16:1-13. Epub 2019 Jan 16.

a Research Center for Molecular Medicine , Hamadan University of Medical Sciences , Hamadan , Iran.

The current study explored the basic molecular mechanisms of zerumbone (ZER), an herbal compound, in inhibiting the migration and invasion of colorectal cancer (CRC) cells in vitro. Two types of CRC cells, namely HCT-116 and SW48, were treated with various concentrations of ZER (8, 16, and 24 µM) for 24, 48, and 72 h, respectively. In vitro assays were performed to determine alterations in proliferation ability, mRNA expression and protein levels, and migration and invasion potential of CRC cells. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1540719DOI Listing
January 2019
2.322 Impact Factor

Role of Heme Iron in the Association Between Red Meat Consumption and Colorectal Cancer.

Nutr Cancer 2019 Jan 14:1-11. Epub 2019 Jan 14.

a Division of Gastroenterology, Hepatology and Nutrition, Department of Life, Health, and Environmental Sciences , University of L'Aquila , L'Aquila , Italy.

The growing incidence of colorectal cancer (CRC) in the world seems to be related to the spread of Westernized lifestyles, particularly dietary habits. Several studies have found that high consumption of red meat-especially processed red meat, a mainstay of Western diets-is associated with an increased risk of developing CRC. One possible reason for the association are the adverse effects exerted by the heme iron contained in red meat, which has the potential to affect homeostasis and colonic epithelial cell renewal and to promote the formation of mutagenic and carcinogenic agents. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1521441DOI Listing
January 2019

Rising Cancer Incidence and Role of the Evolving Diet in Kenya.

Nutr Cancer 2019 Jan 13:1-16. Epub 2019 Jan 13.

c Department of Chemistry and Biochemistry, School of Science , University of Eldoret , Eldoret , Kenya.

Kenya has experienced an increase in the incidence of various types of cancers in the last few decades. This article highlights dietary factors as major contributors to this rising trend of cancer incidence in Kenya at the backdrop of an evolving diet. Literature search revealed that diet plays a major role in the etiology of various cancers with highest incidence rates in various categories of people in Kenya. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1542010DOI Listing
January 2019
2 Reads

Inhibitory Effects of the Extracts of Juglans sigillata Green Husks on the Proliferation, Migration and Survival of KYSE150 and EC9706 Human Esophageal Cancer Cell Lines.

Nutr Cancer 2019 Jan 11:1-10. Epub 2019 Jan 11.

a Tianjin Institute of Acute Abdominal Diseases of Integrated Traditional Chinese and Western Medicine, Tianjin Nankai Hospital , Tianjin , P.R. China.

This study evaluated the antitumor activity of the extracts of green husks of Juglans sigillata Dode on esophageal cancer. KYSE150 EC9706 cells were treated with different concentrations of six components of the extracts of J. sigillata green husks. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/01635581.2018.1
Publisher Site
http://dx.doi.org/10.1080/01635581.2018.1557223DOI Listing
January 2019
8 Reads

Oligonol, a Low Molecular Weight Polyphenol, Enhances Apoptotic Cell Death in Ovarian Cancer Cells via Suppressing NF-κB Activation.

Nutr Cancer 2019 Jan 11:1-8. Epub 2019 Jan 11.

b Department of Obstetrics and Gynecology , Seoul National University Bundang Hospital , Seongnam , Republic of Korea.

Background: Oligonol, a low molecular weight polyphenol derived from lychee fruit, not only has anti-inflammatory effects in various disease conditions but also has antitumor-promoting effects. We evaluate the nuclear factor-kappa B (NF-κB)-related anticancer effect of oligonol in ovarian cancer using SKOV-3 cells.

Methods: Cell viability was examined after oligonol treatment using MTT assay and reactive oxygen species (ROS) production measurement. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/01635581.2018.1
Publisher Site
http://dx.doi.org/10.1080/01635581.2018.1557215DOI Listing
January 2019
3 Reads
2.322 Impact Factor

Nutrition and Swallowing Therapy in Head and Neck Cancer: Utilization of Care and Preventative Efficacy.

Nutr Cancer 2019 Jan 11:1-9. Epub 2019 Jan 11.

b Department of Radiation Oncology, Sylvester Comprehensive Cancer Center , University of Miami , Miami , Florida , USA.

Purpose: To examine the impact of ethnicity, Spanish language preference, socioeconomic status, and treatment setting on utilization of supportive services before radiotherapy (RT) among head and neck cancer patients and to determine whether a lack of these services is associated with an increased rate of adverse events.

Methods And Materials: Demographic, staging, and treatment details were retrospectively collected for patients treated at a safety-net hospital (n = 56) or adjacent private academic hospital (n = 183) from January 1, 2014, to June 30, 2016. Supportive care services evaluated were limited to speech/swallowing therapy and nutrition therapy. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1557220DOI Listing
January 2019
1 Read

Actinidia arguta (Hardy Kiwi) Root Extract Exerts Anti-cancer Effects via Mcl-1-Mediated Apoptosis in Cholangiocarcinoma.

Nutr Cancer 2019 Jan 11:1-11. Epub 2019 Jan 11.

a Department of Radiology , Shengjing Hospital of China Medical University , Shenyang , China.

Cholangiocarcinoma (CCA) is a highly aggressive and chemoresistant liver malignancy. Thus, identification of strategies to overcome insensitivity to apoptosis and growth inhibition is a growing focus of research in this malignancy. This study evaluated the potential anti-cancer effects of an ethanol extract from the Actinidia arguta (Hardy Kiwi) root (RAE) on CCA. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/01635581.2018.1
Publisher Site
http://dx.doi.org/10.1080/01635581.2018.1557218DOI Listing
January 2019
8 Reads
2.322 Impact Factor

Benefits of Oral Nutritional Supplements in Patients with Locally Advanced Nasopharyngeal Cancer during Concurrent Chemoradiotherapy: An Exploratory Prospective Randomized Trial.

Nutr Cancer 2019 Jan 11:1-9. Epub 2019 Jan 11.

a Department of Radiation Oncology , Fudan University Shanghai Cancer Center , Shanghai , China.

Background: Weight loss during chemoradiotherapy is a major problem in patients with head and neck cancer. The aim of this study was to evaluate the effect of ONS on weight, nutritional status and quality of life (QOL) in patients with loco-regionally advanced nasopharyngeal cancer (NPC) undergoing chemoradiotherapy.

Methods: Patients with locally advanced NPC treated at a tertiary hospital in China prior to curative chemoradiotherapy were eligible for this exploratory randomized study. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/01635581.2018.1
Publisher Site
http://dx.doi.org/10.1080/01635581.2018.1557222DOI Listing
January 2019
4 Reads

Association of Activity Altering Genotypes - Tyr113His and His139Arg in Microsomal Epoxide Hydrolase Enzyme with Esophageal Squamous Cell Carcinoma.

Nutr Cancer 2019 Jan 11:1-12. Epub 2019 Jan 11.

a Department of Biochemistry , University of Kashmir , Srinagar , J&K , India.

The study aimed to explore the relationship of microsomal epoxide hydrolase (mEH) exon 3 (Tyr113His) and exon 4 (His139Arg) polymorphisms and predicted mEH activity with esophageal squamous cell carcinoma (ESCC) risk. 482 histologically confirmed cases and equal number of matched controls were analyzed by polymerase chain reaction-restriction length polymorphism (PCR-RFLP). Conditional logistic regression models were used to examine the association of polymorphisms with ESCC. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1484934DOI Listing
January 2019
2.322 Impact Factor

The Potential Influence of Dietary Counseling on Nutritional Status and Dietary Supplement Consumption in Breast Cancer Patients: A Pilot Study.

Nutr Cancer 2019 Jan 11:1-7. Epub 2019 Jan 11.

a University of Life Sciences in Lublin , Faculty of Food Science and Biotechnology , Lublin , Poland.

Introduction: Cancer, in particular breast cancer, is one of the leading causes of death among women. Good nutritional status contributes to the efficacy of treatment and recovery, and nutritional interventions can minimize the adverse effects of cancer therapy.

Aim: The aim of this study was to describe the potential role of dietary counseling in breast cancer patients. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1531138DOI Listing
January 2019

Effect of Phoenix dactylifera L. Sap Against Bleomycin-Induced Pulmonary Fibrosis and Oxidative Stress in Rats: Phytochemical and Therapeutic Assessment.

Nutr Cancer 2019 Jan 9:1-11. Epub 2019 Jan 9.

f Laboratory of Experimental Medicine, Faculty of Medicine of Tunis , University of Tunis El Manar , Tunis , Tunisia.

Lung fibrosis is a lethal interstitial disease characterized by massive proliferation of fibroblast inducing excessive collagen deposition. We aimed to investigate whether Date palm sap (DPS) can play a protective effect on bleomycin (BLM)-induced lung fibrosis in rats. MaleWistar rats were given single dose of BLM (4 mg/kg, intra-tracheal), while DPS (45 mg/kg, intraperitoneal) was administered three days later and continued for three weeks (BLM/DPS group). Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/01635581.2018.1
Publisher Site
http://dx.doi.org/10.1080/01635581.2018.1521442DOI Listing
January 2019
6 Reads
2.322 Impact Factor

The Effect of Oral Administration of PUFAs on the Matrix Metalloproteinase Expression in Gastric Adenocarcinoma Patients Undergoing Chemotherapy.

Nutr Cancer 2019 Jan 8:1-8. Epub 2019 Jan 8.

a Department of Clinical Biochemistry, Faculty of Medicine , Tabriz university of Medical Sciences , Tabriz , Iran.

Objective: Gastric cancer is the third-leading cause of cancer-related mortality and the fifth most common cancer globally. Polyunsaturated fatty acids (PUFAs) are considered as functional ingredients that improve the efficacy of chemotherapeutic drugs. The aim of this study is to investigate the effect of PUFAs administration on matrix metalloproteinases (MMPs). Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/01635581.2018.1
Publisher Site
http://dx.doi.org/10.1080/01635581.2018.1506494DOI Listing
January 2019
7 Reads
2.322 Impact Factor

Undaria pinnatifida a Rich Marine Reservoir of Nutritional and Pharmacological Potential: Insights into Growth Signaling and Apoptosis Mechanisms in Cancer.

Nutr Cancer 2018 Aug-Sep;70(6):956-970. Epub 2019 Jan 7.

a Department of Biological Sciences, College of Natural Sciences , Kongju National University , Chungnam , Republic of Korea.

Seaweeds are an important part of diet consumed in a different part of the world such as New Zealand, Ireland, Wales, and Asian countries including Korea, China, and Japan. In addition, seaweed is nutritious sources possessing health improving effects and therapeutic potential. Recently, one of the widely eaten seaweed species Undaria pinnatifida (U. Read More

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/01635581.2018.1
Publisher Site
http://dx.doi.org/10.1080/01635581.2018.1490449DOI Listing
January 2019
1 Read

Identification and Quantification of Quercetin, A Major Constituent of Artocarpus altilis by Targeting Related Genes of Apoptosis and Cell Cycle: In Vitro Cytotoxic Activity Against Human Lung Carcinoma Cell Lines.

Nutr Cancer 2019 Jan 7:1-14. Epub 2019 Jan 7.

a Department of Biomedical Sciences , Kulliyyah of Allied Health Sciences, International Islamic University Malaysia (IIUM), Jalan Sultan Ahmad Shah, Bandar Indera Mahkota , Kuantan , Pahang , Malaysia.

Nine phenolic compounds were identified and quantified in Artocarpus altilia fruit. One of the main compounds was quercetin, which is the major class of flavonoids has been identified and quantified in pulp part of A. altilis fruit of methanol extract. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1516790DOI Listing
January 2019

Angio-Suppressive Effect of Partially Purified Lectin-like Protein from Musa acuminata pseudostem by Inhibition of VEGF-Mediated Neovascularization and Induces Apoptosis Both In Vitro and In Vivo.

Nutr Cancer 2018 Dec 29:1-16. Epub 2018 Dec 29.

a Post Graduation Department of Biotechnology , Teresian College , Siddhartha Nagar , Mysore , Karnataka , India.

Lifestyle and nutritional changes have contributed much to the somatic genetic changes which have concurrently led to an increase cancer in humans. Hence the plant-based and nutritional involvements block oncogenic transformation are in good demand. We evaluate Phloem exudates of the dietary plant, Musa acuminate pseudostem, the initial domesticated plant species with the effective lectin activity for its functional role against the tumor development and its mechanism of action. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1540714DOI Listing
December 2018
2.322 Impact Factor

Prebiotic Chondroitin Sulfate Disaccharide Isolated from Chicken Keel Bone Exhibiting Anticancer Potential Against Human Colon Cancer Cells.

Nutr Cancer 2018 Dec 29:1-15. Epub 2018 Dec 29.

a Department of Biosciences and Bioengineering , Indian Institute of Technology Guwahati , Guwahati, Assam , India.

Chondroitin sulfate (CS)-Keel disaccharide (CSD) was produced by chondroitin AC lyase (PsPL8A) degradation of food grade CS-Keel polysaccharide isolated from chicken keel cartilage. PsPL8A showed specific activity, 340 ± 5.2 U mg with CS-Keel polysaccharide. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/01635581.2018.1521446DOI Listing
December 2018