394 results match your criteria Nursing Home Acquired Pneumonia


Oral care and nursing home-acquired pneumonia.

Evid Based Dent 2019 Mar;20(1):14-15

Department of Public Health, NHS Fife, Fife, Scotland.

Data sources Cochrane Oral Health Trials Register, Cochrane Central Register of Controlled Trials, MEDLINE, Embase, CINAHL, Chinese Biomedical Literature Database, China National Infrastructure, US National Institutes of Health Ongoing Trials Registry, WHO Clinical Trials Registry, Sciencepaper Online, 19 Chinese dental and nursing journals. Reference lists of included studies were also screened.Study selection Studies were included if they explored oral care with the purpose of reducing pneumonia compared to no oral care, usual care or other oral care measures. Read More

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http://dx.doi.org/10.1038/s41432-019-0002-0DOI Listing

Methicillin-resistant staphylococcus aureus pneumonia in older people: a diagnostic and therapeutic challenge.

Acta Clin Belg 2018 Nov 16:1-4. Epub 2018 Nov 16.

a Department of Internal Medicine , University Hospital Ghent , Ghent , Belgium.

Pneumonia is one of the leading causes of death in older people, with high mortality rates (> 80%). One of the bacterial pathogens causing pneumonia is Staphylococcus aureus. The unique adaptive ability of S. Read More

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http://dx.doi.org/10.1080/17843286.2018.1547854DOI Listing
November 2018
10 Reads

Oral care measures for preventing nursing home-acquired pneumonia.

Cochrane Database Syst Rev 2018 09 27;9:CD012416. Epub 2018 Sep 27.

Department of Oral and Maxillofacial Surgery, State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, NO.14, 3rd Section of Ren Min Nan Road, Chengdu, Sichuan, China, 610041.

Background: Pneumonia occurring in residents of long-term care facilities and nursing homes can be termed 'nursing home-acquired pneumonia' (NHAP). NHAP is the leading cause of mortality among residents. NHAP may be caused by aspiration of oropharyngeal flora into the lung, and by failure of the individual's defence mechanisms to eliminate the aspirated bacteria. Read More

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http://dx.doi.org/10.1002/14651858.CD012416.pub2DOI Listing
September 2018
5 Reads

Decreased relative risk of pneumococcal pneumonia during the last decade, a nested case-control study.

Pneumonia (Nathan) 2018 25;10. Epub 2018 Sep 25.

3Department of Chemical Biochemistry, Section Microbiology, Faculty of Pharmacy and Biochemistry; Hospital de Clínicas, Universidad de Buenos Aires, Buenos Aires, Argentina.

Background: (SP) is one of the most common pathogens of Community-Acquired Pneumonia (CAP), but recent reports suggest that its incidence may be declining in relation to the use of the conjugate 13-valent pneumococcal vaccine in children. We compared the result of the immunochromatographic SP urinary antigen test (SPUAT) and clinical outcomes in patients with CAP admitted in two periods of time: 2001-2002(CAP1) and 2015-2016(CAP2).

Methods: This was a matched nested case-control study of two prospectively recorded cohorts of patients admitted with CAP, with SPUAT and blood culture performed in all patients. Read More

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http://dx.doi.org/10.1186/s41479-018-0053-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154928PMC
September 2018
9 Reads

Frequency and outcome of post-extubation dysphagia using nurse-performed swallowing screening protocol.

Nurs Crit Care 2019 Mar 3;24(2):70-75. Epub 2018 Jul 3.

Medical Doctor, Department of Rehabilitation, Saiseikai Yokohama-shi Tobu Hospital, Yokohama-shi, Kanagawa, Japan.

Background: Post-extubation dysphagia reportedly occurs in 3%-60% of patients and is independently associated with poor patient outcomes.

Aim: The aim of this study was to investigate the frequency of post-extubation dysphagia, as diagnosed using our novel nurse-performed swallowing screening protocol, and to evaluate patient outcomes, including the frequency of discharge home, the length of the intensive care unit and hospital stays, the frequency of hospital-acquired pneumonia and death in the intensive care unit and hospital.

Design: This was a prospective cohort study. Read More

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http://dx.doi.org/10.1111/nicc.12359DOI Listing
March 2019
54 Reads

Ceftolozane-tazobactam for the treatment of multidrug-resistant pneumonia in a patient receiving intermittent hemodialysis.

Am J Health Syst Pharm 2018 May;75(9):e184-e188

Department of Pharmacy, Midtown Medical Center, Columbus Regional Health, Columbus, GA.

Purpose: The safety and effectiveness of ceftolozane-tazobactam for the treatment of multidrug-resistant (MDR) pneumonia in a patient receiving intermittent hemodialysis are reported.

Case Report: A 79-year-old African-American man arrived at an emergency trauma center from a nursing home via ambulance with shortness of breath and potential nasogastric tube misplacement. His medical history included end-stage renal disease (ESRD) for which he was receiving intermittent hemodialysis 3 times per week, hypertension, sacral ulcer, coronary artery bypass graft surgery, and colonization of his airway. Read More

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http://dx.doi.org/10.2146/ajhp170056DOI Listing
May 2018
4 Reads

Naso- and oropharyngeal bacterial carriage in nursing home residents: Impact of multimorbidity and functional impairment.

PLoS One 2018 5;13(1):e0190716. Epub 2018 Jan 5.

Institute of Medical Statistics, Computer Sciences and Documentation, Jena University Hospital, Jena, Thuringia, Germany.

Objective: From April 2013 to February 2014 we performed a multicentre prospective cross-sectional study in 541 German nursing home residents. We determined pharyngeal carriage of Streptococcus pneumoniae (primary objective) and other bacteria (secondary objective) in naso- and oropharyngeal swabs by culture-based standard procedures and explored the influence of multimorbidity and functional status on bacterial carriage.

Methods: Socio-demographic data, vaccination status, multimorbidity, nutrition and functional status defined by Comprehensive Geriatric Assessment were evaluated. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0190716PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5755901PMC
February 2018
6 Reads

Significance of blood cultures in nursing home-acquired pneumonia.

J Infect Chemother 2018 Apr 29;24(4):272-277. Epub 2017 Dec 29.

Department of Respiratory Medicine, Kobe City Medical Center West Hospital, Japan.

The significance of blood cultures in nursing home-acquired pneumonia (NHAP) is incompletely understood. We retrospectively analyzed the clinical and laboratory features of 515 patients with NHAP admitted to our hospital over an 11-year period. Blood cultures were obtained from 336 patients (65. Read More

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http://dx.doi.org/10.1016/j.jiac.2017.11.012DOI Listing
April 2018
5 Reads

Bacterial Pneumonia in Older Adults.

Infect Dis Clin North Am 2017 12 13;31(4):689-713. Epub 2017 Sep 13.

Division of Infectious Diseases, Department of Medicine, University of Michigan, 1150 West Medical Center Drive, Ann Arbor, MI 48109-5680, USA. Electronic address:

The incidence of pneumonia increases with age, and is particularly high in patients who reside in long-term care facilities (LTCFs). Mortality rates for pneumonia in older adults are high and have not decreased in the last decade. Atypical symptoms and exacerbation of underlying illnesses should trigger clinical suspicion of pneumonia. Read More

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http://dx.doi.org/10.1016/j.idc.2017.07.015DOI Listing
December 2017
14 Reads

Professional oral health care for preventing nursing home-acquired pneumonia: A cost-effectiveness and value of information analysis.

J Clin Periodontol 2017 Dec 24;44(12):1236-1244. Epub 2017 Oct 24.

Division of Gerodontology and Removable Prosthodontics, University Clinics of Dental Medicine, Geneva, Switzerland.

Aim: Professional oral health care (POHC) prevents nursing home-acquired pneumonia (NHAP) and its related mortality. We assessed the cost-effectiveness of POHC versus no POHC (nPOHC) and the monetary value of eliminating uncertainty by future research.

Methods: A German public-private payer perspective was adopted. Read More

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http://dx.doi.org/10.1111/jcpe.12775DOI Listing
December 2017
6 Reads

Prevalence, pathogenesis, therapy, and prevention of cardiovascular events in patients with community-acquired pneumonia.

Pneumonia (Nathan) 2016 21;8:11. Epub 2016 Jul 21.

Institute for Cellular and Molecular Medicine, Department of Immunology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.

It is now well recognised that cardiac events occur relatively commonly in patients with acute community-acquired pneumonia. While these events are more frequent in patients with underlying risk factors-such as those with underlying chronic cardiovascular and respiratory comorbidities, the elderly, and in nursing home residents-they also occur in patients with no underlying risks other than severe pneumonia. Recent research elucidating the underlying pathogenic mechanisms related to these cardiac events has indicated a probable role for platelet activation, which is possibly exacerbated by pneumolysin in the case of pneumococcal infections. Read More

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http://dx.doi.org/10.1186/s41479-016-0011-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5471702PMC
July 2016
11 Reads

Predictors of mortality in nursing-home residents with pneumonia: a multicentre study.

Clin Microbiol Infect 2018 Jan 2;24(1):72-77. Epub 2017 Jun 2.

Division of Infectious and Tropical Diseases, Hospital of Lodi, Lodi, Italy.

Objectives: To evaluate predictors of mortality in patients residing in nursing-homes (NHs) or long-term care facilities (LTCFs) with diagnosis of NH-acquired pneumonia (NHAP).

Methods: We conducted an observational, prospective study (December 2013-December 2015) of patients residing in nine NHs/LTCFs of Central and Northern Italy with diagnosis of NHAP. Data on demographics, comorbidities, microbiology, and therapies were entered into an electronic database. Read More

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http://dx.doi.org/10.1016/j.cmi.2017.05.023DOI Listing
January 2018
5 Reads

Additional Cost Because of Pneumonia in Nursing Home Residents: Results From the Incidence of Pneumonia and Related Consequences in Nursing Home Resident Study.

J Am Med Dir Assoc 2017 May;18(5):453.e7-453.e12

Gérontopôle, University Hospital of Toulouse, Toulouse, France; University of Toulouse III Paul Sabatier, Toulouse, France.

Objectives: Pneumonia is a frequent condition in older people. Our aim was to examine the total healthcare cost related to pneumonia in nursing home (NH) residents over a 1-year follow-up period.

Design: This was a prospective, longitudinal, observational, and multicenter study that was a part of the Incidence of Pneumonia and related Consequences in Nursing Home Resident study. Read More

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http://dx.doi.org/10.1016/j.jamda.2017.01.021DOI Listing
May 2017
24 Reads

Clinical characteristics and outcome of healthcare associated pneumonia in Turkey.

Tuberk Toraks 2016 Sep;64(3):185-190

Clinic of Chest Diseases, Adiyaman State Hospital, Adiyaman, Turkey.

Introduction: Pneumonia in cases with preceding hospitalization, hemodialysis, intravenous therapy, wound care, or chemotherapy within the prior 30 days and residence in nursing homes are defined as healthcare associated pneumonia (HCAP). The aim of this study was to compare the demographic and laboratory data, isolated causative agents and prognosis of patients with community-acquired pneumonia (CAP) and HCAP in a large population in Turkey.

Materials And Methods: The data of 785 cases (average age 65. Read More

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September 2016
10 Reads

Discharge disposition as an independent predictor of readmission among patients hospitalised for community-acquired pneumonia.

Int J Clin Pract 2017 Mar;71(3-4)

Section of Hospital Medicine, Department of Medicine, University of Chicago, Chicago, IL, USA.

Background: Community-acquired pneumonia (CAP) is the most common non-obstetrical reason for hospital admission, the leading infectious cause of death, and a target for public reporting. CAP has thus become a target of quality improvement and pay-for-performance efforts. However, the relationship between discharge disposition and readmission risk has not been investigated. Read More

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http://dx.doi.org/10.1111/ijcp.12935DOI Listing
March 2017
18 Reads

Clinical impact and prevalence of MRSA CC398 and differences between MRSA-Tet and MRSA-Tet in an area of Spain with a high density of pig farming: a prospective cohort study.

Clin Microbiol Infect 2017 Sep 29;23(9):678.e1-678.e4. Epub 2017 Mar 29.

Department of Medicine, Universitat Autònoma de Barcelona, Spain; Infectious Diseases Unit, Health Sciences Research Institute of the Germans Trias i Pujol Foundation, Badalona, Barcelona, Spain; CIBER de Enfermedades Respiratorias, Madrid, Spain.

Objectives: Tetracycline resistance (Tet) is a phenotypic marker of the livestock-associated methicillin-resistant Staphylococcus aureus (MRSA) CC398 clone. The aim of this study was to analyse the prevalence of MRSA CC398 in patients in contact with healthcare facilities and differences between patients with MRSA-Tet and MRSA tetracycline-susceptible (Tet) strains.

Methods: Patients diagnosed with MRSA from January 2012 to December 2015 were divided into two groups, MRSA-Tet and MRSA-Tet. Read More

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http://dx.doi.org/10.1016/j.cmi.2017.03.019DOI Listing
September 2017
4 Reads

Nursing home-acquired pneumonia, dysphagia and associated diseases in nursing home residents: A retrospective, cross-sectional study.

Geriatr Nurs 2017 Sep - Oct;38(5):437-441. Epub 2017 Mar 25.

Department of Oral Function and Prosthetic Dentistry, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands.

Background: Nursing home-acquired pneumonia (NHAP) is a common infection among nursing home residents. There is also a high prevalence of dysphagia in nursing home residents and they suffer more often from comorbidity and multimorbidity. This puts nursing home residents at higher risk of (mortality from) NHAP. Read More

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http://dx.doi.org/10.1016/j.gerinurse.2017.02.007DOI Listing
November 2017
20 Reads

Evaluation of an ultraviolet room disinfection protocol to decrease nursing home microbial burden, infection and hospitalization rates.

BMC Infect Dis 2017 03 3;17(1):186. Epub 2017 Mar 3.

University of Wisconsin-Milwaukee, 1921 East Hartford Avenue, Milwaukee, WI, 5321, USA.

Background: The focus of nursing home infection control procedures has been on decreasing transmission between healthcare workers and residents. Less evidence is available regarding whether decontamination of high-touch environmental surfaces impacts infection rates or resident outcomes. The purpose of this study was to examine if ultraviolet disinfection is associated with changes in: 1) microbial counts and adenosine triphosphate counts on high-touch surfaces; and 2) facility wide nursing home acquired infection rates, and infection-related hospitalization. Read More

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http://dx.doi.org/10.1186/s12879-017-2275-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335784PMC
March 2017
5 Reads

The Prevalence of Oropharyngeal Dysphagia in Danish Patients Hospitalised with Community-Acquired Pneumonia.

Dysphagia 2017 06 22;32(3):383-392. Epub 2016 Dec 22.

Department of Physiotherapy and Occupational Therapy, Metropolitan University College, Copenhagen, Denmark.

Community-acquired pneumonia (CAP) and oropharyngeal dysphagia (OD) are prevalent conditions in the elderly. The aim of this study was to explore the relationship between CAP, OD, and frailty in patients admitted to a department of respiratory medicine at a regional hospital. The outcome was mortality during hospitalization and within 30 days of discharge and rehospitalization within 30 days of discharge. Read More

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http://dx.doi.org/10.1007/s00455-016-9765-zDOI Listing
June 2017
8 Reads

Severity Assessment and the Immediate and Long-Term Prognosis in Community-Acquired Pneumonia.

Semin Respir Crit Care Med 2016 12 13;37(6):886-896. Epub 2016 Dec 13.

Department of Respiratory Medicine, Maastricht University Medical Center, Maastricht, The Netherlands.

Severity assessment is a crucial step in the initial management of patients with community-acquired pneumonia (CAP). While approximately half of patients are at low risk of death and can be safely treated as outpatients, around 20% are at increased risk. While CURB-65 (confusion, respiratory rate, blood pressure, urea) and pneumonia severity index (PSI) scores are equally useful as an adjunct to clinical judgment to identify patients at low risk, the so-called minor American Thoracic Society/Infectious Diseases Society of America criteria are predictive of patients in need of intensified treatment (i. Read More

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http://dx.doi.org/10.1055/s-0036-1592127DOI Listing
December 2016
23 Reads

Antimicrobial Resistance and Clinical Outcomes in Nursing Home-Acquired Pneumonia, Compared to Community-Acquired Pneumonia.

Yonsei Med J 2017 Jan;58(1):180-186

Division of Pulmonary and Critical Care Medicine, Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang, Korea.

Purpose: Patients with nursing home-acquired pneumonia (NHAP) should be treated as hospital-acquired pneumonia (HAP) according to guidelines published in 2005. However, controversy still exists on whether the high mortality of NHAP results from multidrug resistant pathogens or underlying disease. We aimed to outline differences and factors contributing to mortality between NHAP and community-acquired pneumonia (CAP) patients. Read More

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http://dx.doi.org/10.3349/ymj.2017.58.1.180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5122635PMC
January 2017
22 Reads

Association Between Results of Quality Assessment of Long-Term Care Facilities and Hospital-Acquired Pneumonia in Individuals with Stroke or Neurodegenerative Disease in Korea.

J Am Geriatr Soc 2016 12 21;64(12):e311-e313. Epub 2016 Nov 21.

Institute of Health Services Research, Department of Preventive Medicine, College of Medicine, Yonsei University, Seoul, Korea.

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http://dx.doi.org/10.1111/jgs.14536DOI Listing
December 2016
3 Reads

The Impact of Disability and Social Determinants of Health on Condition-Specific Readmissions beyond Medicare Risk Adjustments: A Cohort Study.

J Gen Intern Med 2017 01 15;32(1):71-80. Epub 2016 Nov 15.

Department of Internal Medicine, Division of General Medicine, University of Michigan Medical School, 2800 Plymouth Road, Building 16, 430W, Ann Arbor, MI, 48109, USA.

Background: Readmission rates after pneumonia, heart failure, and acute myocardial infarction hospitalizations are risk-adjusted for age, gender, and medical comorbidities and used to penalize hospitals.

Objective: To assess the impact of disability and social determinants of health on condition-specific readmissions beyond current risk adjustment.

Design, Setting, And Participants: Retrospective cohort study of Medicare patients using 1) linked Health and Retirement Study-Medicare claims data (HRS-CMS) and 2) Healthcare Cost and Utilization Project State Inpatient Databases (Florida, Washington) linked with ZIP Code-level measures from the Census American Community Survey (ACS-HCUP). Read More

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http://dx.doi.org/10.1007/s11606-016-3869-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215164PMC
January 2017
59 Reads

Role of Atypical Bacteria in Hospitalized Patients With Nursing Home-Acquired Pneumonia.

Hosp Pharm 2016 Oct;51(9):768-777

Nursing home-acquired pneumonia (NHAP) has been identified as one of the leading causes of mortality and hospitalization for long-term care residents. However, current and previous pneumonia guidelines differ on the appropriate management of NHAP in hospitalized patients, specifically in regard to the role of atypical bacteria such as Chlamydiae pneumonia, Mycoplasma pneumoniae, and Legionella. The purpose of this review is to evaluate clinical trials conducted in hospitalized patients with NHAP to determine the prevalence of atypical bacteria and thus the role for empiric antibiotic coverage of these pathogens in NHAP. Read More

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http://dx.doi.org/10.1310/hpj5109-768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5080996PMC
October 2016
7 Reads

Erratum to: Nursing home-acquired pneumonia presenting at the emergency department.

Intern Emerg Med 2017 03;12(2):279

Medicina Interna 4, Hospital Santa Marta, CHLC, Lisbon, Portugal.

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http://link.springer.com/10.1007/s11739-016-1557-9
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http://dx.doi.org/10.1007/s11739-016-1557-9DOI Listing
March 2017
4 Reads

The use of ertapenem for the treatment of community-acquired pneumonia in routine hospital practice: a matched cohort study.

Rev Esp Quimioter 2016 Oct 8;29(5):259-64. Epub 2016 Sep 8.

Dolores Sousa. Department of Infectious Diseases. Complexo Hospitalario Universitario A Coruña. Xubias de arriba 84, 15006. A Coruña. Spain.

Objective: The clinical response to ertapenem in community-acquired pneumonia (CAP) at the setting of routine hospital practice has been scarcely evaluated.

Methods: We retrospectively compared CAP cases treated with ertapenem or with other standard antimicrobials (controls) at a tertiary 1,434-bed center from 2005 to 2014.

Results: Out of 6,145 patients hospitalized with CAP, 64 (1%) ertapenem-treated and 128 controls were studied (PSI IV-V 72%, mean age 73 years. Read More

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October 2016
4 Reads

A New Prognosis Score to Predict Mortality After Acute Pneumonia in Very Elderly Patients.

J Am Med Dir Assoc 2016 12 3;17(12):1123-1128. Epub 2016 Sep 3.

Department of Geriatrics and Internal Medicine, Hospital of Champmaillot, University Hospital, Dijon, France; UMR Inserm/U1093 Cognition, Action, Sensorimotor Plasticity, University of Burgundy, Dijon, France. Electronic address:

Objectives: Acute pneumonia (AP) induces an excess of mortality among the elderly. We evaluated the value of a new predictive biomarker index compared to usual prognosis scores for predicting in-hospital and 1-year mortalities in elderly inpatients with AP.

Design: Retrospective study in 6 clinical departments of a university hospital. Read More

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http://dx.doi.org/10.1016/j.jamda.2016.07.018DOI Listing
December 2016
6 Reads

Multicenter Osteopathic Pneumonia Study in the Elderly: Subgroup Analysis on Hospital Length of Stay, Ventilator-Dependent Respiratory Failure Rate, and In-hospital Mortality Rate.

J Am Osteopath Assoc 2016 Sep;116(9):574-87

Context: Osteopathic manipulative treatment (OMT) is a promising adjunctive treatment for older adults hospitalized for pneumonia.

Objective: To report subgroup analyses from the Multicenter Osteopathic Pneumonia Study in the Elderly (MOPSE) relating to hospital length of stay (LOS), ventilator-dependent respiratory failure rate, and in-hospital mortality rate.

Design: Multicenter randomized controlled trial. Read More

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http://dx.doi.org/10.7556/jaoa.2016.117DOI Listing
September 2016
6 Reads

Changes in physical function after hospitalization in patients with nursing and healthcare-associated pneumonia.

J Infect Chemother 2016 Oct 1;22(10):662-6. Epub 2016 Aug 1.

Department of Internal Medicine I, Kawasaki Medical School, Okayama, Japan.

To clarify the functional changes after hospitalization due to pneumonia in elderly Japanese patients, we investigated the changes in physical functioning, nutritional routes, and diet that occurred after hospitalization in patients with nursing and healthcare-associated pneumonia (NHCAP). We analyzed 405 patients with NHCAP and compared findings with 448 patients with community-acquired pneumonia (CAP). Among the NHCAP patients, 140 (34%) patients showed a decline in activities of daily living function between baseline and discharge. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S1341321X163009
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http://dx.doi.org/10.1016/j.jiac.2016.06.005DOI Listing
October 2016
8 Reads

Oral Health and Hospital-Acquired Pneumonia in Elderly Patients: A Review of the Literature.

J Dent Hyg 2016 Jun;90 Suppl 1:15-21

Purpose: The U.S. spends an average of $6. Read More

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June 2016
25 Reads

Anthropometric measurements may be informative for nursing home-acquired pneumonia.

Pak J Med Sci 2016 May-Jun;32(3):694-9

Aysegul Yildirim Kaptanoglu, MD. Professor, Trakya University, Faculty of Health Sciences, Department of the Health Management Section, Edirne, Turkey.

Objective: To evaluate the relationship between anthropometric measurements and Nursing Home-Acquired Pneumonia (NHAP) risk.

Methods: Consecutive patients of 65 years or elderly who were living in the Balikli Rum Hospital Nursing Homes were included in this prospective study. At the beginning of this study, the patients' anthropometrics values were measured. Read More

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http://dx.doi.org/10.12669/pjms.323.9635DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928425PMC
July 2016
5 Reads

Association of influenza with severe pneumonia/empyema in the community, hospital, and healthcare-associated setting.

Respir Med Case Rep 2016 24;19:1-4. Epub 2016 May 24.

Division of Infectious Diseases and Infection Control, Tohoku Medical and Pharmaceutical University Hospital, Sendai City, Miyagi, Japan; Laboratory for Clinical Microbiology, Tohoku Medical and Pharmaceutical University Hospital, Sendai City, Miyagi, Japan.

Unlabelled: We presented three cases of influenza-related severe pneumonia/empyema that occurred in one season.

Case 1: A 76-year-old diabetic man, developed empyema as a result of severe community-acquired pneumonia (CAP) secondary to Haemophilus influenzae, as confirmed on sputum culture. Nasal swab was positive for influenza A antigen. Read More

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http://dx.doi.org/10.1016/j.rmcr.2016.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908279PMC
June 2016
7 Reads

Predictive and prognostic factors in patients with blood-culture-positive community-acquired pneumococcal pneumonia.

Eur Respir J 2016 09 12;48(3):797-807. Epub 2016 May 12.

Dept of Pneumology, Hospital Clinic of Barcelona - Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Ciber de Enfermedades Respiratorias (CIBERES), Barcelona, Spain

In patients with pneumococcal community-acquired pneumonia (CAP), the risk factors for bacteraemia and its impact on outcomes are not fully elucidated. We aimed to compare characteristics of patients with blood-culture-positive versus blood-culture-negative pneumococcal CAP, and to characterise bacteraemic serotypes.We describe a prospective, observational study on nonimmunocompromised patients with pneumococcal CAP, from 1996 to 2013. Read More

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http://dx.doi.org/10.1183/13993003.00039-2016DOI Listing
September 2016
29 Reads

Community-Acquired Pneumonia Due to Multidrug- and Non-Multidrug-Resistant Pseudomonas aeruginosa.

Chest 2016 Aug 7;150(2):415-25. Epub 2016 Apr 7.

Department of Pneumology, Institut Clinic del Tórax, Hospital Clinic of Barcelona - Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona - SGR 911- Ciber de Enfermedades Respiratorias (Ciberes) Barcelona, Spain. Electronic address:

Background: Pseudomonas aeruginosa is not a frequent pathogen in community-acquired pneumonia (CAP). However, in patients with severe CAP, P aeruginosa can be the etiology in 1.8% to 8. Read More

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http://dx.doi.org/10.1016/j.chest.2016.03.042DOI Listing
August 2016
47 Reads

Defining characteristics and risk indicators for diagnosing nursing home-acquired pneumonia and aspiration pneumonia in nursing home residents, using the electronically-modified Delphi Method.

BMC Geriatr 2016 Mar 7;16:60. Epub 2016 Mar 7.

BENECOMO, Flemish-Netherlands Geriatric Oral Research Group, Ghent, Belgium.

Background: In nursing home residents, it is not possible to distinguish pneumonia and aspiration pneumonia clinically. International literature reveals no consensus on which and how many characteristics and risk indicators must be present to diagnose (nursing home-acquired) pneumonia and aspiration pneumonia. The aim of this survey was to reach consensus among a panel of clinical medical experts in geriatrics and pulmonology about the characteristics required for diagnosing pneumonia, and about the risk indicators needed to consider the diagnosis aspiration pneumonia in nursing home residents with pneumonia. Read More

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http://dx.doi.org/10.1186/s12877-016-0231-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4782327PMC
March 2016
6 Reads

Nursing home-acquired pneumonia presenting at the emergency department.

Intern Emerg Med 2016 Oct 7;11(7):999-1004. Epub 2016 Mar 7.

Medicina Interna 4, Hospital Santa Marta, CHLC, Lisbon, Portugal.

Nursing home-acquired pneumonia (NHAP) is one of the most common infections arising amongst nursing home residents, and its incidence is expected to increase as population ages. The NHAP recommendation for empiric broad-spectrum antibiotic therapy, arising from the concept of healthcare-associated pneumonia, has been challenged by recent studies reporting low rates of multidrug-resistant (MDR) bacteria. This single center study analyzes the results of NHAP patients admitted through the Emergency Department (ED) at a tertiary center during the year 2010. Read More

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http://link.springer.com/10.1007/s11739-016-1412-z
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http://dx.doi.org/10.1007/s11739-016-1412-zDOI Listing
October 2016
5 Reads

Efficacy of 23-valent pneumococcal polysaccharide vaccine in preventing community-acquired pneumonia among immunocompetent adults: A systematic review and meta-analysis of randomized trials.

Vaccine 2016 Mar 17;34(13):1496-1503. Epub 2016 Feb 17.

Department of Respiratory Medicine, Peking University Third Hospital, Beijing, China. Electronic address:

Background: Data on the efficacy of the 23-valent pneumococcal polysaccharide vaccine (PPV-23) in preventing adult community-acquired pneumonia (CAP) among the target population of individuals aged over 65 years and high-risk individuals aged 19-64 years are conflicting. As the Advisory Committee on Immunization Practices (ACIP) has recently demonstrated PPV-23 is likely beneficial to immunocompromised adults by the Grading, Assessment, Development, and Evaluation (GRADE) framework, we conducted meta-analysis to examine its efficacy in an immunocompetent population.

Methods: We searched the PUBMED, EMBASE, and Cochrane Library databases for randomized trials. Read More

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http://dx.doi.org/10.1016/j.vaccine.2016.02.023DOI Listing
March 2016
29 Reads

Experiences of nursing staff caring for patients with methicillin-resistant Staphylococcus aureus.

Int Nurs Rev 2016 Jun 6;63(2):233-41. Epub 2016 Feb 6.

Sophiahemmet University and Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, Sweden.

Background: Methicillin-resistant Staphylococcus aureus is a resistant variant of S. aureus and can cause pneumonia, septicaemia and, in some cases, death. Caring for patients with antibiotic resistant bacteria is a challenge for healthcare personnel. Read More

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http://doi.wiley.com/10.1111/inr.12245
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http://dx.doi.org/10.1111/inr.12245DOI Listing
June 2016
5 Reads

Facility characteristics as independent prognostic factors of nursing home-acquired pneumonia.

Korean J Intern Med 2016 Mar 2;31(2):296-304. Epub 2016 Feb 2.

Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Myongji Hospital, Seonam University College of Medicine, Goyang, Korea.

Background/aims: Recently, the incidence of nursing home-acquired pneumonia (NHAP) has been increasing and is now the leading cause of death among nursing home residents. This study was performed to identify risk factors associated with NHAP mortality, focusing on facility characteristics.

Methods: Data on all patients ≥ 70 years of age admitted with newly diagnosed pneumonia were reviewed. Read More

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http://dx.doi.org/10.3904/kjim.2014.256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4773711PMC
March 2016
8 Reads

Efficacy of PPV23 in Preventing Pneumococcal Pneumonia in Adults at Increased Risk--A Systematic Review and Meta-Analysis.

PLoS One 2016 13;11(1):e0146338. Epub 2016 Jan 13.

Pfizer Deutschland GmbH, Linkstr. 10, 10785, Berlin, Germany.

Background: Pneumococcal community-acquired pneumonia (pCAP) is the most frequent form of pneumonia. The elderly and adults with underlying diseases are at an increased risk of developing pCAP. The 23-valent pneumococcal polysaccharide vaccine (PPV23) was licensed over 30 years ago and is recommended as the standard intervention in many countries across the globe, although its efficacy continues to be debated. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0146338PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711910PMC
July 2016
19 Reads

Impact of microbiological samples in the hospital management of community-acquired, nursing home-acquired and hospital-acquired pneumonia in older patients.

Eur J Clin Microbiol Infect Dis 2016 Mar 11;35(3):489-95. Epub 2016 Jan 11.

Department of Geriatrics and Internal Medicine, Hospital of Champmaillot, University Hospital, Dijon, France.

We investigated the positivity rate, the detection rates for non-covered pathogens and the therapeutic impact of microbiological samples (MS) in community-acquired pneumonia (CAP), nursing home-acquired pneumonia (NHAP) and hospital-acquired pneumonia (HAP) in elderly hospitalised patients. Patients aged 75 years and over with pneumonia and hospitalised between 1/1/2013 and 30/6/2013 in the departments of medicine (5) and intensive care (1) of our university hospital were included. Microbiological findings, intra-hospital mortality and one-year mortality were recorded. Read More

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http://link.springer.com/10.1007/s10096-015-2565-9
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http://dx.doi.org/10.1007/s10096-015-2565-9DOI Listing
March 2016
7 Reads

An investigation of multimorbidity measures as risk factors for pneumonia in elderly frail patients admitted to hospital.

Eur J Intern Med 2016 Mar 11;28:102-6. Epub 2015 Dec 11.

Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy; Internal Medicine and Critical Subacute Care Unit, Geriatric-Rehabilitation Department, Parma University Hospital, Parma, Italy.

Objectives: To investigate the association of different chronic comorbidities, considered singularly and together in Cumulative Illness Rating Scale (CIRS) indexes, with pneumonia diagnosis in a group of elderly frail hospitalized patients.

Design And Methods: With a retrospective cohort design, all clinical records of frail (Rockwood ≥ 5) nonterminal patients ≥ 65 years old acutely admitted over a 8-month span in an internal medicine ward were evaluated. Pneumonia status and its categorization (community-acquired, CAP, vs healthcare-associated, HCAP) were defined according to chest radiology findings and validated criteria. Read More

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http://dx.doi.org/10.1016/j.ejim.2015.11.021DOI Listing
March 2016
20 Reads

The treatment of nursing home-acquired pneumonia using a medically intensive Hospital in the Home service.

Med J Aust 2015 Dec;203(11):441-2

NHMRC National Centre for Antimicrobial Stewardship and Guidance, Doherty Institute for Infection and Immunity, Melbourne, VIC.

Objectives: To compare the outcomes for patients with nursing home-acquired pneumonia (NHAP) treated completely in a Hospital in the Home (HITH) setting with those of patients treated in a traditional hospital ward.

Design: Case-control study.

Setting And Participants: All patients admitted by the Royal Melbourne Hospital for treatment of NHAP from 1 July 2013 to 31 January 2014. Read More

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December 2015
19 Reads

A Systematic Review of Interventions to Change Staff Care Practices in Order to Improve Resident Outcomes in Nursing Homes.

PLoS One 2015 11;10(11):e0140711. Epub 2015 Nov 11.

Dementia Collaborative Research Centre: Carers and Consumers, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia.

Background: We systematically reviewed interventions that attempted to change staff practice to improve long-term care resident outcomes.

Methods: Studies met criteria if they used a control group, included 6 or more nursing home units and quantitatively assessed staff behavior or resident outcomes. Intervention components were coded as including education material, training, audit and feedback, monitoring, champions, team meetings, policy or procedures and organizational restructure. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0140711PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641718PMC
June 2016
12 Reads

Clinical characteristics of nursing home-acquired pneumonia in elderly patients admitted to a Korean teaching hospital.

Korean J Intern Med 2015 Sep 27;30(5):638-47. Epub 2015 Aug 27.

Department of Internal Medicine, Jeju National University School of Medicine, Jeju, Korea.

Background/aims: Nursing home-acquired pneumonia (NHAP) is included under healthcare-associated pneumonia. However, the optimal treatment strategy for NHAP has been controversial in several studies. We evaluated the clinical features of NHAP compared to community-acquired pneumonia (CAP) in elderly patients admitted with pneumonia. Read More

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http://dx.doi.org/10.3904/kjim.2015.30.5.638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578015PMC
September 2015
21 Reads

Opening of a respiratory intermediate care unit in a general hospital: impact on mortality and other outcomes.

Respiration 2015 8;90(3):235-42. Epub 2015 Jul 8.

Department of Pneumology and Respiratory Intermediate Care Unit, University Hospital of Cattinara, Trieste, Italy.

Background: Respiratory intermediate care units (RICUs) are specialized areas aimed at optimizing the cost-benefit ratio of care. No data exist about the impact of opening a RICU on hospital outcomes.

Objectives: We wondered if opening a RICU may improve the outcomes of patients with acute respiratory failure (ARF), acute exacerbation of chronic obstructive pulmonary disease (AECOPD), or community-acquired pneumonia (CAP). Read More

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http://dx.doi.org/10.1159/000433557DOI Listing
July 2016
17 Reads

Impact of bacterial coinfection on clinical outcomes in pneumococcal pneumonia.

Eur J Clin Microbiol Infect Dis 2015 Sep 10;34(9):1839-47. Epub 2015 Jun 10.

Department of Respiratory Medicine, Kurashiki Central Hospital, 1-1-1 Miwa, Kurashiki, Okayama, 710-0052, Japan,

The aim of this study was to investigate the influence of bacterial coinfection on patients with pneumococcal pneumonia. We retrospectively analyzed the incidence, clinical features, microbial distributions, and outcomes of patients with bacterial coinfection in a cohort of 433 hospitalized patients with pneumococcal pneumonia. Eighty-five patients (19. Read More

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http://link.springer.com/10.1007/s10096-015-2421-y
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http://dx.doi.org/10.1007/s10096-015-2421-yDOI Listing
September 2015
4 Reads

Metallo-β-lactamase-producing infection in a non-hospital environment.

Acute Med Surg 2016 01 27;3(1):32-35. Epub 2015 Apr 27.

Clinical Laboratory Center Gunma University Hospital Maebashi Gunma Japan.

Case: A 92-year-old female resident at a nursing home was transported to the emergency department unconscious, hypotensive, and febrile. Chest X-rays and computed tomography revealed a permeation shadow in the right lung. The patient was diagnosed with sepsis due to pneumonia. Read More

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http://dx.doi.org/10.1002/ams2.120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667230PMC
January 2016
5 Reads