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    146 results match your criteria Nummular Dermatitis

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    Typical and atypical clinical appearance of atopic dermatitis.
    Clin Dermatol 2017 Jul - Aug;35(4):354-359. Epub 2017 Mar 24.
    Icahn School of Medicine at Mt Sinai, New York, NY. Electronic address:
    Atopic dermatitis is a complex, systemic inflammatory disorder associated with a variety of clinical features. The original criteria of Hanifin and Rajka include major criteria and a list of about two dozen minor criteria however, even the minor criteria do not include some features of atopic dermatitis noted less commonly but still seen with some frequency. This contribution first reviews the common clinical appearance of atopic dermatitis in infancy, childhood, and adulthood, as well as the less typical appearances, including lichenoid atopic dermatitis; juvenile plantar dermatosis; nummular-type atopic dermatitis; follicular atopic dermatitis; alopecia of atopic dermatitis; eczema coxsackium; and psoriasiform, perineal, and lip licker's dermatitis. Read More

    Chemical Tattoo Treatment Leading to Systemic Cobalt Hypersensitivity.
    Skinmed 2017 1;15(3):221-222. Epub 2017 Jun 1.
    Department of Dermatology, Medical College of Wisconsin, Milwaukee, WI;
    An otherwise healthy 36-year-old Caucasian woman, without prior history of atopic dermatitis or eczema, presented to an outside dermatologist with a generalized, severely pruritic eruption involving the entire body except the face. One month previously, she had used a 50% trichloroacetic acid tattoo removal solution on a blue-colored tattoo on the medial aspect of the left ankle. The patient's eruption persisted for 7 months, and after several attempts to slowly taper her prednisone dose, she presented to our institution. Read More

    Adult-Onset Atopic Dermatitis: Fact or Fancy?
    Dermatol Clin 2017 Jul;35(3):299-302
    Department of Dermatology, Oregon Health & Science University, 3303 Bond Avenue, Portland, OR 97239, USA. Electronic address:
    Atopic dermatitis therapy can be a challenge in many cases. Persistence into adulthood often reflects the more severe cases and such patients have the added problems of hand eczema and thick nummular lesions that resist topical medications. Within this group are patients labeled as having adult-onset atopic dermatitis, a designation that is hard to define and probably represents those whose childhood eczema was simply forgotten. Read More

    The histopathological differentiation between palmar psoriasis and hand eczema: A retrospective review of 96 cases.
    J Am Acad Dermatol 2017 Jul 9;77(1):130-135. Epub 2017 Feb 9.
    Department of Dermatology, Hallym University Sacred Heart Hospital, Anyang, Korea.
    Background: The histopathologic differences among palmar psoriasis (PP), hand eczema (HE), and hyperkeratotic hand dermatitis (HHD) have been poorly described.

    Objectives: We sought to distinguish among PP, HE, and HHD on a histopathologic basis.

    Methods: We retrospectively analyzed the histology of hematoxylin-eosin-stained sections obtained from 96 patients diagnosed with PP, HE, or HHD. Read More

    [Nummular dermatitis: report of two cases in children].
    Arch Argent Pediatr 2016 Aug 1;114(4):e241-4. Epub 2016 Aug 1.
    Centro de Salud "Severo Ochoa", Gijón, Asturias, España.
    Nummular eczema or dermatitis is an uncommon paediatric pathology. It is presented as red-purplish small papules and vesicles that join to form exudative circular patches and then to eczematous or lichenified patches with discoid shape. The lesions appear predominantly on the extensor surface of extremities, although they can appear in trunk, hands or feet. Read More

    Leprosy in the Bible.
    Clin Dermatol 2016 Jan-Feb;34(1):3-7. Epub 2015 Nov 17.
    Domestic and Specialized Medicine Centre "Dilmed", ul. Bohaterów Monte Cassino 3, 40-231 Katowice, Poland. Electronic address:
    For many years, the biblical term tzaraat has referred to leprosy. In fact, the disease or diseases described under this name have no relationship to leprosy, as it was known in the Middle Ages or today; moreover, the term referred not only to skin disease, but also to the state of the ritual impurity and punishment for the sins. Although the real nature of tzaraat remains unknown, the differential diagnosis might include the following: Psoriasis, seborrheic dermatitis, favus, dermatophyte infections, nummular dermatitis, atopic dermatitis, pityriasis rosea, crusted scabies, syphilis, impetigo, sycosis barbae, alopecia areata, furuncles, scabies, neurodermatitis, scarlet fever, lupus erythematosus, lichen sclerosus et atrophicus, folliculitis decalvans, morphea, sarcoidosis, and lichen planopilaris. Read More

    [The Dutch College of General Practitioners practice guideline 'Eczema'].
    Ned Tijdschr Geneeskd 2014 ;158:A8009
    *Namens de werkgroep NHG-standaard 'Eczeem', waarvan de leden aan het eind van dit artikel staan vermeld.
    The Dutch College of General Practitioners practice guideline 'Eczema' provides recommendations for the diagnosis and treatment of common types of eczema: atopic dermatitis, contact dermatitis, acro-vesicular eczema, nummular eczema, hypostatic eczema, and asteatotic eczema. Age is an important factor when determining the type of eczema. According to the guideline, patient history and physical examination are sufficient in the diagnosis of eczema; additional investigations are rarely indicated. Read More

    Patch test results of hand eczema patients: relation to clinical types.
    J Eur Acad Dermatol Venereol 2015 May 15;29(5):940-7. Epub 2014 Sep 15.
    Department of Dermatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
    Background: Allergic contact dermatitis is a well-known cause of hand eczema, although the influence of contact allergens on different clinical types of hand eczema remains still unclear.

    Objective: To identify most common positive tested allergens among hand eczema patients and to define the relation between specific contact allergies and clinical types of hand eczema according to the guidelines of the Danish Contact Dermatitis Group (DCDG).

    Methods: We included 1571 hand eczema subjects who were patch tested from 1 January 2002 to 31 December 2013. Read More

    Clinical features and aggravating factors in nummular eczema in Thais.
    Asian Pac J Allergy Immunol 2013 Mar;31(1):36-42
    Department of Dermatology, Mahidol University, Bangkok, Thailand.
    Background: Nummular eczema is an idiopathic inflammatory skin disease that mostly has a chronic and relapsing course. Many factors are thought to be responsible for this condition, such as atopic dermatitis, dry skin, emotional stress or seasonal variation.

    Objective: The purpose of the study was to assess clinical findings and aggravating factors of nummular eczema and to evaluate characteristics, severity of disease and quality of life of patients. Read More

    Nummular eczema and contact allergy: a retrospective study.
    Dermatitis 2012 Jul-Aug;23(4):153-7
    Department of Internal Medicine and Clinical Oncology-Section of Dermatology, University of Bari Medical School, Bari, Italy.
    Background: Etiopathogenesis of nummular eczema is obscure; many causative factors have been proposed. Only a few studies investigated the relevance of contact allergy.

    Objective: This retrospective study aimed to investigate the role of contact allergy in the underlying mechanism of nummular eczema. Read More

    Skin diseases in rural Yucatan, Mexico.
    Int J Dermatol 2012 Jul;51(7):823-8
    Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
    Objectives: There are no known reports of the frequency of skin diseases endemic to rural Yucatan, Mexico. The aim of this study was to report the prevalence of dermatologic conditions in rural villages in that region.

    Methods: We conducted a retrospective descriptive study of all cases of skin disease diagnosed by a team of American board-certified dermatologists during consultations in January 2009, August 2009, and June 2010, in the state of Yucatan, Mexico. Read More

    Less common clinical manifestations of atopic dermatitis: prevalence by age.
    Pediatr Dermatol 2012 Sep-Oct;29(5):580-3. Epub 2012 Apr 2.
    Outpatient Department, Hospital Nacional de Niños Benjamin Bloom, San Salvador, El Salvador.
    The common manifestations of atopic dermatitis (AD) appear sequentially with involvement of the cheeks in infancy, flexural extremities in childhood, and hands in adulthood. Although less common clinical manifestations are well described, they have not been the subject of epidemiologic studies to describe their prevalence in specific age groups. This observational, cross-sectional, comparative study included 131 children younger than 18 of both sexes with AD who attended the clinics of the Dermatology Department of the National Institute of Pediatrics in Mexico City. Read More

    A comparative analysis of mast cell quantification in five common dermatoses: lichen simplex chronicus, psoriasis, lichen planus, lupus, and insect bite/allergic contact dermatitis/nummular dermatitis.
    ISRN Dermatol 2012 1;2012:759630. Epub 2012 Feb 1.
    Department of Pathology and Laboratory Medicine, University of Florida College of Medicine-Jacksonville, Jacksonville, FL 32209, USA.
    There is a large body of literature demonstrating an important role of mast cells in adaptive and innate immunity. The distribution of mast cells in the skin varies in different parts of the body. It is well known that mast cells are important for effector functions of classic IgE-associated allergic disorders as well as in host defense against infective agents and influence the manifestation of autoimmune diseases. Read More

    Clinical features of the extrinsic and intrinsic types of adult-onset atopic dermatitis.
    Asia Pac Allergy 2011 Jul 28;1(2):80-6. Epub 2011 Jul 28.
    Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
    Background: Most study concerning the prevalence and dermatological manifestations of the extrinsic and the intrinsic form of atopic dermatitis (AD) were performed in children and adult AD related to the early-onset AD extending to adult life. Adult-onset AD is a subgroup of AD. Apart from the typical eczematous flexural distribution pattern of AD, this group may also have nontypical morphology and localization. Read More

    Shape and configuration of skin lesions: grouped herpetiform.
    Clin Dermatol 2011 Sep-Oct;29(5):509-10
    Department of Endocrinological and Medical Sciences, Section of Dermatology, University of Genoa,Viale Benedetto XV No. 7, 16132 Genova, Italy.
    Lesions that may present in a grouped way include diseases with grouped vesicles such as dyshidrosis, nummular dermatitis, herpes simplex, and herpes zoster; diseases with grouped vesicobullae such as dermatitis herpetiformis, herpes gestationis, subacute lupus erythematosus in the bullous variant, and pemphigus herpetiformis; and diseases with grouped pustules such as pustular psoriasis, dermatitis continua of Hallopeau, and impetigo herpetiformis. Read More

    Retrospective study of intraepidermal nerve fiber distribution in biopsies of patients with nummular eczema.
    Am J Dermatopathol 2011 Aug;33(6):621-3
    Colworth Discover, Colworth Science Park, Sharnbrook, Bedfordshire, United Kingdom.
    Background: Nummular eczema is a chronic inflammatory condition characterized by pruritus and histologically characterized by spongiosis. The etiology is unknown, and the lesions frequently arise spontaneously. Neuropeptides contribute to mediating and maintaining eczematous conditions. Read More

    Dermal dendritic cells in psoriasis, nummular dermatitis, and normal-appearing skin.
    J Am Acad Dermatol 2012 Jan 12;66(1):98-105. Epub 2011 Jun 12.
    Department of Dermatology, Penn State Hershey Medical Center, Hershey, Pennsylvania 17033, USA.
    Background: The reason psoriasis (PSO) favors extensor skin is unknown. We hypothesized that PSO may involve extensor skin preferentially because of differences in the number or type of dermal dendritic cells (dDCs) between flexural and extensor skin.

    Objective: We sought to compare dDC type and distribution in normal-appearing flexural and extensor skin, PSO, and nummular dermatitis (ND). Read More

    Classification of hand eczema: clinical and aetiological types. Based on the guideline of the Danish Contact Dermatitis Group.
    Contact Dermatitis 2011 Jul;65(1):13-21
    Department of Dermato-Allergology, National Allergy Research Centre, Copenhagen University Gentofte Hospital, 2900 Hellerup, Denmark.
    Background: No generally accepted classification scheme for hand eczema exists. The Danish Contact Dermatitis Group recently developed a guideline defining common clinical types and providing criteria for aetiological types.

    Objectives: To test the concepts of this guideline in a group of hand eczema patients. Read More

    Arcuate, annular, and polycyclic inflammatory and infectious lesions.
    Clin Dermatol 2011 Mar-Apr;29(2):140-50
    UMDNJ-New Jersey Medical School, 185 South Orange Avenue, Medical Science Building Room C520, Newark, NJ 07103-2714, USA.
    Common shapes encountered in dermatologic diseases include linear, nummular, annular, polycyclic, and arciform. The last three have a relatively restricted differential, which must be entirely explored. It is not uncommon for a single disease to present in annular, arciform or polycyclic configurations; moreover, the lesions may evolve from being arciform to annular and then become polycyclic. Read More

    Non-typical morphology and localization in Turkish atopic dermatitis patients with onset before the age of 18 years.
    Indian J Dermatol Venereol Leprol 2011 Jan-Feb;77(1):23-7
    Department of Dermatology and Venereology, Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey.
    Background: Hanifin and Rajka's criteria (HRC) are the gold standard for the diagnosis of atopic dermatitis (AD). Apart from the age-related distribution and typical morphology of the lesions as defined in one of the major criteria of HRC, patients may also show nontypical morphology and localization.

    Aim: The aim of this study was to find the frequency of nontypical morphology and localization in Turkish AD patients with onset before the age of 18 years, who were diagnosed according to HRC. Read More

    Phenotypes of atopic dermatitis.
    J Dtsch Dermatol Ges 2011 Jan 4;9(1):12-20. Epub 2010 Nov 4.
    Department of Medicine, Section of Dermatology and Venereology, University of Verona, Italy.
    Atopic dermatitis (AD) is a common disease affecting both children and adults. AD develops from a complex interplay between environmental, genetic, immunologic and biochemical factors. Genetic factors predispose atopic subjects to mount exaggerated Th2 responses and to a poorly efficient epidermal barrier, which may be sufficient to initiate inflammation in the skin and may favor allergic sensitization. Read More

    Methotrexate is a safe and effective treatment for paediatric discoid (nummular) eczema: a case series of 25 children.
    Australas J Dermatol 2010 May;51(2):128-30
    Royal Children's Hospital, Parkville, Melbourne, Victoria, Australia.
    We present a case series of 25 paediatric patients with refractory discoid eczema treated with methotrexate. Patients were commenced on either 5 mg or 10 mg of methotrexate per week. Sixteen patients (64%) completely cleared their eczema after an average of 10. Read More

    Dental infection associated with nummular eczema as an overlooked focal infection.
    J Dermatol 2009 Aug;36(8):462-5
    Department of Dermatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan.
    Nummular eczema is a common skin disease, but the pathoetiology has yet to be elucidated. We report here a case of severe nummular eczema. Although the skin lesions were resistant to topical corticosteroids, the patient became responsive to treatment and no recurrence was noted after the eradication of dental infections. Read More

    An update on pityriasis rosea and other similar childhood exanthems.
    Curr Opin Pediatr 2009 Aug;21(4):481-5
    Pediatrics and Dermatology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA.
    Purpose Of Review: Pityriasis rosea is a common skin condition seen in children and adults. Whereas pityriasis rosea is a benign condition, it is important to distinguish it from other childhood exanthems.

    Recent Findings: Pityriasis rosea can present in a variety of manners. Read More

    Sensitizing potential of triclosan and triclosan-based skin care products in patients with chronic eczema.
    Dermatol Ther 2008 Oct;21 Suppl 2:S35-8
    Section of Dermatology and Venereology, Department of Biomedical and Surgical Sciences, University of Verona, Verona, Italy.
    Triclosan is a lypophilic chlorophenol biocide with broad-spectrum antibacterial and antifungal activity. Triclosan-based topical products have been shown to be tolerated and beneficial in atopic dermatitis. The aim of this study was to evaluate the sensitizing potential of triclosan and triclosan-based creams in patients affected by eczematous dermatitis. Read More

    Cytokine-induced CEACAM1 expression on keratinocytes is characteristic for psoriatic skin and contributes to a prolonged lifespan of neutrophils.
    J Invest Dermatol 2009 Mar 9;129(3):671-81. Epub 2008 Oct 9.
    Inserm, U844, Montpellier, France.
    Carcinoembryonic antigen-related cellular adhesion molecule 1 (CEACAM1) is a cell-surface glycoprotein, belonging to the carcinoembryonic antigen family, expressed by human neutrophils, epithelial cells, activated T and NK cells. CEACAM1 is expressed as a cell-surface molecule with different isoforms or can be secreted as a soluble protein. Here, we show that keratinocytes in the outer epidermal layer of psoriatic skin express CEACAM1, unlike those in healthy skin or in cutaneous lesions of patients with atopic or nummular dermatitis. Read More

    Adult-onset atopic dermatitis: a cross-sectional study of natural history and clinical manifestation.
    Asian Pac J Allergy Immunol 2007 Dec;25(4):207-14
    Department of Dermatology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
    The previously reported prevalence of adult-onset atopic dermatitis (AD) varied from 13% to 47%. There were a few reports of clinical features of adult-onset AD. The purpose of this article was to study the clinical features of Thai patients with adult-onset AD. Read More

    Lichen planus-like atopic dermatitis: expanding the differential diagnosis of spongiotic dermatitis.
    J Cutan Pathol 2008 Mar;35(3):311-4
    Department of Dermatology, Drexel University, Philadelphia, PA, USA.
    Spongiotic dermatitis represents a commonly encountered histopathological pattern seen by dermatopathologists. The differential diagnosis of lymphocyte predominant acute spongiotic dermatitis typically entails atopic dermatitis (AD), contact dermatitis, nummular dermatitis, pityriasis rosea and seborrheic dermatitis. Recently, our group has characterized a distinct subtype of spongiotic dermatitis occurring exclusively in heavily pigmented patients. Read More

    The differential diagnosis of atopic dermatitis in childhood.
    Dermatol Ther 2006 Mar-Apr;19(2):73-82
    Oregon Health and Sciences University, Portland, 97239, USA.
    Atopic is the most common of the dermatitides seen in infancy and childhood, but there are numerous other diseases that can mimic the skin findings. These include seborrheic dermatitis, immunodeficiency, and psoriasis in infancy; scabies, tinea corporis infection, perioral, nummular, contact, and molluscum dermatitis in childhood. It is sometimes extremely difficult to differentiate between ichthyosis and AD, and it is also important to differentiate AD from erythrodermic conditions including acrodermatitis enteropathica, biotin deficiency, and Netherton syndrome. Read More

    Relevance of patch testing in patients with nummular dermatitis.
    Indian J Dermatol Venereol Leprol 2005 Nov-Dec;71(6):406-8
    Department of Dermatology, Manipal Hospital, Bangalore, Karnataka, India.
    Background: A chronic dermatosis like nummular dermatitis may be complicated by contact dermatitis due to an impaired cutaneous barrier. This study is aimed at evaluating secondary contact dermatitis in patients with nummular dermatitis.

    Methods: Patch testing with the Indian Standard Series was performed in 50 of 78 patients with a clinical diagnosis of nummular eczema. Read More

    Successful treatment of chronic persistent vesicular hand dermatitis with topical pimecrolimus.
    Saudi Med J 2005 Dec;26(12):1989-91
    Dermatology Department, College of Medicine, King Faisal University, Al-Khobar, Kingdom of Saudi Arabia.
    Hand dermatitis is a common chronic skin condition that has many clinical forms including contact, hyperkeratotic, frictional, nummular, atopic, pompholyx and chronic vesicular hand dermatitis. Topical steroids are the first line agents used. Here, we report the successful response to topical pimecrolimus 1% cream in a patient with steroid resistant chronic vesicular hand dermatitis. Read More

    Soak and smear: a standard technique revisited.
    Arch Dermatol 2005 Dec;141(12):1556-9
    Department of Dermatology, University of Pennsylvania, 3600 Spruce Street, 2 Maloney Building, Philadelphia, PA 19104, USA.
    Background: Atopic dermatitis, nummular eczema, chronic hand dermatitis, palmar plantar psoriasis, and xerotic eczema are common inflammatory skin conditions. They may be refractory to conventional topical and even systemic treatment. Little evidence is available that demonstrates the benefits of aggressive topical treatment of patients with these disorders. Read More

    Eosinophilic pustular folliculitis in infancy: not a distinctive inflammatory disease of the skin.
    Am J Dermatopathol 2005 Oct;27(5):443-55
    Department of Dermatology, Friedrich-Schiller-University of Jena, Germany.
    In the standard literature of dermatology and dermatopathology "eosinophilic pustular folliculitis in infancy" is presented as a distinctive inflammatory disease of the skin, to wit, a variant of "Ofuji's eosinophilic folliculitis". Assessment critically of the first publication devoted to the subject revealed a potpourri of findings clinical and histopathologic, with no clear criteria being set forth by the authors to enable diagnosis, with precision. Our review of all articles dedicated to the matter of "eosinophilic pustular folliculitis in infancy" shows that criteria for diagnosis are found with great difficulty. Read More

    Adult-onset atopic dermatitis.
    J Am Acad Dermatol 2005 Apr;52(4):579-82
    Department of Dermatology, Istanbul University, Istanbul, Turkey.
    Adult-onset atopic dermatitis (AD) is a recently introduced subgroup of AD. Apart from the most typical flexural lichenified/exudative pattern in adults, patients may also have nontypical morphology and localization. The aim of this retrospective study was to find the frequency of nontypical morphology and localization in adult-onset AD and to evaluate the accuracy of United Kingdom Working Party's criteria in detecting those cases. Read More

    Contact dermatitis of the feet: a study of 53 cases.
    Dermatitis 2004 Sep;15(3):125-30
    Department of Medicine--Clinic of Dermatology, Santa Casa de São Paulo-Medical School, São Paulo, Brazil.
    Background: Contact dermatitis of the feet is a common dermatosis that very often makes patients unable to perform daily activities. The differential diagnosis should be made with other dermatoses, such as tinea, atopic dermatitis, psoriasis, dyshidrosis, and nummular eczema. It is clinically difficult to establish a true diagnosis of contact dermatitis, and the results of epicutaneous tests may not be definite. Read More

    Retrospective survey of patch testing at department of dermatology and venerology, zagreb university hospital center in zagreb, croatia.
    Acta Dermatovenerol Croat 2004 ;12(4):261-7
    Department of Dermatology and Venerology Zagreb University Hospital Center, Salata 4, 10000 Zagreb, Croatia.
    Epicutaneous (patch) test is a standard test to confirm contact allergy. During a six-year period (1998-2003), contact allergic dermatitis was diagnosed in 4132 (65%) of 6341 patients using standard patch test with a Croatian series of allergens according to the International Contact Dermatitis Research Group (ICDRG). The most common clinical diagnoses related to contact allergy (male; female) were contact allergic dermatitis (65. Read More

    Lesional T cells and dermal dendrocytes in psoriasis plaque express increased levels of granulysin.
    J Am Acad Dermatol 2004 Dec;51(6):1006-8
    Psoriasis Research Institute, Palo Alto and Stanford University School of Medicine, Palo Alto, California, USA.
    Granulysin is a broad-spectrum potent antimicrobial peptide produced by the immunocytes. We determined granulysin levels in certain cutaneous inflammatory diseases and correlated expression of granulysin with the relative risks of secondary infections in these conditions. In immunohistochemistry stains a monoclonal antigranulysin antibody was used at 1:150 dilutions. Read More

    Textile dermatitis in patients with contact sensitization in Israel: a 4-year prospective study.
    J Eur Acad Dermatol Venereol 2004 Sep;18(5):531-7
    Dermatology Clinic, Meir Hospital, 44281, Kfar Saba, affiliated with the Sackler School of Medicine, Tel Aviv University, Israel.
    Background: The exact incidence of textile dermatitis is unknown because of the lack of controlled epidemiological studies. Nevertheless, the increasing frequency of contact dermatitis to clothing has been demonstrated, thus indicating the importance of further investigations in this field.

    Objective: To analyse the results from a 4-year prospective study of the clinical and aetiological features of contact dermatitis to textiles in Israel. Read More

    Helicobacter pylori-positive patients with pruritic skin diseases are at increased risk for gastric cancer.
    Aliment Pharmacol Ther 2004 Jul;20 Suppl 1:80-4
    Health Administration Center, Wakayama University, Japan.
    Background: Helicobacter pylori infection has been implicated as a possible cause of extraintestinal disorders such as skin diseases. A number of case reports describe patients with skin diseases, such as prurigo nodularis, that are associated with gastric cancer.

    Aim: The aim of this study was to examine the prevalence of H. Read More

    Histological study of necrolytic acral erythema.
    J Ark Med Soc 2004 Apr;100(10):354-5
    Department of Dermatology, Faculty of Medicine Ain Shams University, Cairo, Egypt.
    Described in 1996, necrolytic acral erythema remains the sole diagnostic cutaneous marker for hepatitis C virus infection. To date only eight cases have been described in literature, a fact that makes full histological description and appreciation of the disease process inadequate. Thirty necrolytic acral erythema cases were biopsied and detailed histological description was performed by three separate dermatopathologists who were blinded as to clinical presentation. Read More

    Severe, generalized nummular eczema secondary to interferon alfa-2b plus ribavirin combination therapy in a patient with chronic hepatitis C virus infection.
    Arch Dermatol 2004 Feb;140(2):215-7
    Harvard Medical School, Boston, Massachusetts, USA.
    Background: With increasing rates of hepatitis C virus infection and diagnosis, more patients are being treated with interferon alfa-2b plus ribavirin therapy. Cutaneous side effects to combination therapy are common and may limit treatment. There are few previous case reports of generalized eczematous dermatoses occurring after combination therapy for hepatitis C virus, none in a North American patient, and none of this severity or recalcitrance. Read More

    Cutaneous diseases in Asians.
    Dermatol Clin 2003 Oct;21(4):669-77
    Department of Dermatology, Henry Ford Health System, 2799 West Grand Boulevard, Detroit, MI 48202, USA.
    Atopic dermatitis, nummular dermatitis, dyshidrosis, and melasma seem to be more common in Asians, whereas psoriasis and skin cancer are less common. In addition, there are less common skin conditions that are usually seen in Asians, including Mongolian spot, nevus of Ota, nevus of Ito, Kawasaki disease, primary cutaneous amyloidosis, Kikuchi-Fujimoto disease, and LCAI. Awareness of these less common cutaneous disorders can be helpful, especially for clinicians who work in areas with a large Asian population. Read More

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