51,085 results match your criteria Nose Anatomy


Pigmented Melanotic Schwannoma of the Neck: Report of 2 Cases and Review of the Literature.

Ear Nose Throat J 2019 Feb 13;98(2):102-106. Epub 2019 Feb 13.

1 Department of Otolaryngology-Head and Neck Surgery, Thomas Jefferson University, Philadelphia, PA, USA.

Background:: Melanotic schwannoma is a rare tumor with indeterminate biologic behavior and varying treatment recommendations.

Methods:: We report 2 cases of pigmented melanotic schwannoma of the head and neck and perform literature review. The pathologic and immunohistochemical characteristics of melanotic schwannoma are reviewed. Read More

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http://dx.doi.org/10.1177/0145561319826542DOI Listing
February 2019

Computed Tomography Description of the Uncinate Process Angulation in Patients With Cystic Fibrosis and Comparison With Primary Ciliary Dyskinesia, Nasal Polyposis, and Controls.

Ear Nose Throat J 2019 Feb 7;98(2):89-93. Epub 2019 Feb 7.

1 Ear Nose and Throat Department and Cystic Fibrosis Centre, Intercommunal Hospital of Créteil, Paris, France.

Background:: There is a medial bulging of the lateral nasal wall in patients with cystic fibrosis (CF).

Aims:: Uncinate process (UP) angulation measurements in patients and controls to objectify this bulging.

Materials And Methods:: Thirty CF, 17 primary ciliary dyskinesia (PCD), 13 chronic rhinosinusitis with polyps (CRSwp), and 30 controls were included. Read More

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http://dx.doi.org/10.1177/0145561319828645DOI Listing
February 2019

An Unknown Renaissance Portrait of Tagliacozzi (1545-1599), the Founder of Plastic Surgery.

Authors:
Sophie Ménard

Plast Reconstr Surg Glob Open 2019 Jan 4;7(1):e2006. Epub 2019 Jan 4.

Yale University, New Haven, Conn.

This article examines a recently discovered painting of a young scholar holding a reconstructed nose. Experts in ancient paintings have confirmed that the portrait is an authentic painting of the School of Bologna in Italy, from the last quarter of the Renaissance. In the 1580s, Gaspare Tagliacozzi (1545-1599), a young professor in surgery and anatomy at the University of Bologna, Italy, was the only one to carry out reconstructions of the nose and other missing parts of the face. Read More

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http://dx.doi.org/10.1097/GOX.0000000000002006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6382240PMC
January 2019
2 Reads

Microscopic anatomy of sensory receptors.

Authors:
Nicholas J Wade

J Hist Neurosci 2019 Mar 11:1-22. Epub 2019 Mar 11.

a Department of Psychology , University of Dundee , Dundee , Scotland , United Kingdom.

Experiences following stimulation of the senses have been recorded for millennia, and they could be related to the gross anatomy of the sense organs. Examination of their microanatomy was to await the development of achromatic microscopes in the early nineteenth century. Among the microscopic structures that were isolated and described were specialized sensory cells, called receptors, and they could be related to the stimuli that excited them. Read More

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http://dx.doi.org/10.1080/0964704X.2018.1554298DOI Listing

Estimation of nares-to-epiglottis distance for selecting an appropriate nasopharyngeal airway.

Medicine (Baltimore) 2019 Mar;98(10):e14832

Department of Anesthesiology, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan.

The nasopharyngeal airway is an important equipment in airway management, a correct placement is crucial for its effectiveness. We measured the nares-to-epiglottis distance (NED) and examined the correlations of the optimal insertion length (NED-1) with patient characteristics and various external facial measurements. We aimed to develop a simple method for estimating the optimal insertion length and to help select an appropriate nasopharyngeal airway. Read More

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http://dx.doi.org/10.1097/MD.0000000000014832DOI Listing
March 2019
1 Read

Evaluation of apertura piriformis and related cranial anatomical structures through computed tomography: Golden ratio.

Folia Morphol (Warsz) 2019 Mar 5. Epub 2019 Mar 5.

Istanbul Medeniyet University, Faculty of Medicine,Department of Biostatistics and Medical Informatics,Istanbul, Turkey, Istanbul Medeniyet University, Faculty of Medicine,Department of Biostatistics and Medical Informatics,Istanbul, Turkey, 34000 İstanbul, Turkey.

Background: The purpose of study was to evaluate normal morphometric measurements of piriform aperture (PA) by limiting the age range in genders to show the morphometry of the relevant and close proximal cranial structures; and also to investigate whether these are in compliance with the golden ratio.

Materials And Methods: Our study was performed on 83 (42 female, 41 male) multidetector computed tomography images obtained from patients. A total of 14 morphological measurements were performed including the height of PA, the width of PA and 12 cranial structures; and these measurements were evaluated for compliance with the golden ratio. Read More

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http://dx.doi.org/10.5603/FM.a2019.0021DOI Listing

How to characterize a nasal product. The state of the art of in vitro and ex vivo specific methods.

Int J Pharm 2019 Feb 26;561:47-65. Epub 2019 Feb 26.

Laboratoire de Pharmacie Galénique et de Biopharmacie, Université libre de Bruxelles (ULB), Brussels, Belgium.

Nasal delivery offers many benefits over other conventional routes of delivery (e.g. oral or intravenous administration). Read More

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http://dx.doi.org/10.1016/j.ijpharm.2019.02.026DOI Listing
February 2019

Intra-fraction motion gating during frameless Gamma Knife Icon™ therapy: The relationship between cone beam CT assessed intracranial anatomy displacement and infrared-tracked nose marker displacement.

J Radiosurg SBRT 2019 ;6(1):67-76

Leeds Cancer Centre, St. James's University Hospital, Leeds, LS9 7TF, UK.

Methods: Gamma Knife Icon™'s high-definition motion management (HDMM) system gates treatment delivery should intra-fraction displacement of a nose marker exceed some user-defined threshold. A method, previously-validated with a phantom, is used to relate intra-fractional displacements of the nose marker to displacements of patient targets. Additionally, novel analysis is performed to ascertain the relationship between nose marker displacement and displacement of a 3D grid of coordinates throughout stereotactic space. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355448PMC
January 2019

Detecting Happiness Using Hyperspectral Imaging Technology.

Comput Intell Neurosci 2019 15;2019:1965789. Epub 2019 Jan 15.

College of Computer and Information Science, Southwest University, Chongqing, China.

Hyperspectral imaging (HSI) technology can be used to detect human emotions based on the power of material discrimination from their faces. In this paper, HSI is used to remotely sense and distinguish blood chromophores in facial tissues and acquire an evaluation indicator (tissue oxygen saturation, StO) using an optical absorption model. This study explored facial analysis while people were showing spontaneous expressions of happiness during social interaction. Read More

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http://dx.doi.org/10.1155/2019/1965789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350538PMC
January 2019
1 Read

Infant Midnasal Stenosis: Reliability of Nasal Metrics.

AJNR Am J Neuroradiol 2019 Mar 14;40(3):562-567. Epub 2019 Feb 14.

Division of Pediatric Otolaryngology-Head and Neck Surgery (K.M.L., S.H.P., J.R.S.), University of Utah and Primary Children's Hospital, Salt Lake City, Utah

Background And Purpose: Midnasal stenosis is a poorly defined entity that may be a component of other conditions of nasal obstruction contributing to respiratory distress in infants. We sought to establish whether midnasal vault narrowing is a component of well-defined syndromes of nasal narrowing, such as bilateral choanal atresia and pyriform aperture stenosis, and to characterize the nasal anatomy of patients with syndromic craniosynostosis.

Materials And Methods: A convenience sample of patients with pyriform aperture stenosis, bilateral choanal atresia, and Apert and Crouzon syndromes with maxillofacial CT scans was identified. Read More

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http://dx.doi.org/10.3174/ajnr.A5980DOI Listing
March 2019
1 Read

Treatment of Facial Telangiectases With Glycerin Sclerotherapy.

Dermatol Surg 2019 Feb 6. Epub 2019 Feb 6.

Park Avenue Dermatology, Orange Park, Florida.

Background: Sclerotherapy is used to treat varicosities and telangiectases. Glycerin is a sclerosing agent that has been used off-label for years with a favorable adverse effect profile. However, the treatment of facial telangiectases with sclerotherapy is controversial given the potential for necrosis and embolization in relation to the complex vascular anatomy of the face. Read More

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http://dx.doi.org/10.1097/DSS.0000000000001824DOI Listing
February 2019

Nasal Parameters, Nostrils Shapes and Philtral Column Shape: A Morphometric Analysis in Nepalese Medical Undergraduate Students.

J Nepal Health Res Counc 2019 Jan 28;16(41):462-466. Epub 2019 Jan 28.

Department of Oral Pathology, KIST Medical College and Hospital, Imadole Kathmandu, Nepal.

Background: The nose is a pyramidal shaped structure situated in the midline of midface being attached to the facial skeleton. The shape, size and spatial location of the nose-philtrum-upper lip complex are important from aesthetic point of view. Hence, to study the nasal parameters, shape of nostril and philtrum among the undergraduate students remained as the main aim of this study. Read More

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January 2019
1 Read

Computer-Aided Facial Reconstruction of "Mary-Magdalene" Relics Following Hair and Skull Analyses.

Clin Med Insights Ear Nose Throat 2019 14;12:1179550618821933. Epub 2019 Jan 14.

UVSQ (DANTE Laboratory EA 4498), UFR of Health Sciences, Montigny-Le-Bretonneux, France.

The supposed relics of "Mary-Magdalene" are preserved in Provence (France) in an ancient tradition. They consist of a dry skull and a lock of hair. For the first time, they were officially subjected to an extensive medico-surgical examination by photogrammetry, high-magnification binocular lenses, scanning electron microscope, and energy-dispersive X-ray elemental analysis, to propose a full computer-aided facial reconstruction. Read More

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http://dx.doi.org/10.1177/1179550618821933DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343449PMC
January 2019
4 Reads

Unconventional Endovascular Access for Symptomatic Thoracic Aortic Ulcer with Infrarenal Aortic Occlusion-A Case Report.

Ann Vasc Surg 2019 Feb 4. Epub 2019 Feb 4.

Humanitas Clinical and Research Center, Rozzano, Milan, Italy; Humanitas University Department of Biomedical Sciences, Rozzano, Milan, Italy. Electronic address:

Background: A man in very poor general condition was admitted for acute thrombosis of the infrarenal aorta associated to a penetrating aortic ulcer (PAU) of the distal thoracic aorta.

Methods: We planned a two-stage procedure: an axillobifemoral revascularization to be followed by thoracic endovascular aortic repair (TEVAR) after rehabilitation. Before the second stage, the patient presented with acute respiratory failure secondary to an abrupt PAU evolution. Read More

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http://dx.doi.org/10.1016/j.avsg.2018.10.049DOI Listing
February 2019
2 Reads

Etiopathogenesis of Primary Acquired Nasolacrimal Duct Obstruction: What We Know and What We Need to Know.

Ophthalmic Plast Reconstr Surg 2019 Jan 25. Epub 2019 Jan 25.

Institute of Functional and Clinical Anatomy, Friedrich Alexander University Erlangen-Nürnberg, Erlangen, Germany.

Purpose: To provide a systematic review of the literature on the etiopathogenesis of primary acquired nasolacrimal duct obstruction (PANDO).

Methods: The authors performed a PubMed search of all articles published in English with specific reference to etiopathogenesis of PANDO or associations of PANDO. Data captured include demographics, study techniques, hypothesis, presumed or confirmed interpretations with regards to pathogenesis, mechanisms, or pathways. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001310DOI Listing
January 2019

Evaluation of the antioxidant effects of different histone deacetylase inhibitors (HDACis) on human lens epithelial cells (HLECs) after UVB exposure.

BMC Ophthalmol 2019 Feb 4;19(1):42. Epub 2019 Feb 4.

Eye Institute, Eye and Ear, Nose, and Throat Hospital of Fudan University, 83 Fenyang Road, Shanghai, 200031, People's Republic of China.

Background: To compare the protective effects of the histone deacetylase inhibitors (HDACis) β-hydroxybutyrate (βOHB), trichostatin A (TSA), suberoylanilide hydroxamic acid (SAHA) and valproic acid (VPA) on human lens epithelial cells(HLECs) following ultraviolet-B (UVB) exposure.

Methods: HLECs were divided into subgroups: four HDACi groups, a control group, a UVB-treated group and a DMSO group (cells treated with DMSO and UVB irradiation). In the HDACi groups, HLECs were cultured with different concentrations of HDACis 12 h prior to UVB irradiation. Read More

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http://dx.doi.org/10.1186/s12886-019-1056-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360693PMC
February 2019
3 Reads

Malignant peripheral nerve sheath tumor of the nasal cavity and nasopharynx in a child: A case report.

Medicine (Baltimore) 2019 Jan;98(4):e14223

Department of Radiology, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.

Rationale: Malignant peripheral nerve sheath tumors (MPNSTs) are rare neoplasms with only a few reported cases affecting the nasal cavity, paranasal sinuses, and anterior skull base.

Patient Concerns: A 12-year-old girl with a mass in her nose was admitted to the Department of Otorhinolaryngology of Shenzhen Children's Hospital. She had a 4-month history of progressive, unilateral right nasal obstruction, unilateral mucopurulent rhinorrhea, foul nasal odor, snoring, hyposmia, occasional epistaxis, and no headache, no facial numbness, without eye swelling and vision loss. Read More

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http://dx.doi.org/10.1097/MD.0000000000014223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358413PMC
January 2019
7 Reads
5.723 Impact Factor

Metastases to the nose from clear cell renal cell carcinoma: A case report.

Medicine (Baltimore) 2019 Jan;98(4):e14012

Department of Oncology.

Rationale: Patients with nasal metastases are seldom seen among clear cell renal cell carcinoma (CCRCC). We report a rare case presenting as a solitary nasal cutaneous nodule, and summarize the therapeutic experience of tyrosine kinase inhibitors (TKIs).

Patient Concerns: A 86-year-old man with a chief complaint of continuous back pain for 3 months and discovery of a cutaneous nodule on the nose for a month visited the oncology department of our hospital. Read More

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http://dx.doi.org/10.1097/MD.0000000000014012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358352PMC
January 2019
7 Reads

Bone wax migrates to the orbit in a patient with a frontal sinus abnormality: a case report.

BMC Ophthalmol 2019 Jan 24;19(1):29. Epub 2019 Jan 24.

Department of Ophthalmology, the 2nd Xiangya Hospital, Central South University, Changsha, 410011, Hunan Province, China.

Background: Bone wax is the most widely used hemostatic bone sealant because of its availability, ease of use, immediate action, and minimal adverse effects. Several complications have been reported to be associated with the use of bone wax, such as infection, osteohypertrophy, pain, granuloma formation, allergic reaction, and thrombosis. Here, we present a rare complication, namely, bone wax migration, which developed after a craniotomy on a patient who had a frontal sinus abnormality. Read More

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http://dx.doi.org/10.1186/s12886-019-1037-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345031PMC
January 2019
2 Reads

[Clinical differences between primary nasopharyngeal NK/T-cell lymphoma and primary nasal cavity NK/T-cell lymphoma with nasopharynx extension].

Zhonghua Zhong Liu Za Zhi 2019 Jan;41(1):56-62

Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

To investigate the clinical and prognostic differences between primary nasopharyngeal natural killer (NK)/T-cell lymphoma (NP NKTCL) and extranodal NK/T-cell lymphoma of the nasal cavity with nasopharynx extension (N-NP NKTCL). A total of 89 patients with NP NKTCL and 113 patients with N-NP NKTCL from January 2000 to June 2015 were retrospectively analyzed. Clinical and pathological features, treatment responses and prognosis were compared between the two groups. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0253-3766.2019.01.010DOI Listing
January 2019

A distinct neurodevelopmental syndrome with intellectual disability, autism spectrum disorder, characteristic facies, and macrocephaly is caused by defects in CHD8.

J Hum Genet 2019 Apr 22;64(4):271-280. Epub 2019 Jan 22.

College of Science and Engineering, Hamad Bin Khalifa University, Doha, Qatar.

A decade ago, we described novel de novo submicroscopic deletions of chromosome 14q11.2 in three children with developmental delay, cognitive impairment, and similar dysmorphic features, including widely-spaced eyes, short nose with flat nasal bridge, long philtrum, prominent Cupid's bow of the upper lip, full lower lip, and auricular anomalies. We suggested that this constituted a new multiple congenital anomaly-intellectual disability syndrome due to defects in CHD8 and/or SUPT16H. Read More

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http://dx.doi.org/10.1038/s10038-019-0561-0DOI Listing
April 2019
1 Read
2.462 Impact Factor

Potential life-threatening complication of tonsillectomy: cervicofacial surgical emphysema.

BMJ Case Rep 2019 Jan 20;12(1). Epub 2019 Jan 20.

Otolaryngology Department, NHS Lothian, Livingston, UK.

A 30-year-old woman presented to the accident and emergency department 3 days post-tonsillectomy with bleeding from the tonsillar fossa and left-sided facial swelling. The patient denied any dysphagia or breathing difficulties but experienced pain on neck movement. On examination, although the bleeding had stopped on reaching the emergency department, a small clot was noted in her left tonsillar fossa. Read More

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http://dx.doi.org/10.1136/bcr-2018-228377DOI Listing
January 2019
7 Reads

Repeated gestational exposure to diesel engine exhaust affects the fetal olfactory system and alters olfactory-based behavior in rabbit offspring.

Part Fibre Toxicol 2019 01 17;16(1). Epub 2019 Jan 17.

NeuroBiologie de l'Olfaction, INRA, Université Paris-Saclay, 78350, Jouy-en-Josas, France.

Background: Airborne pollution, especially from diesel exhaust (DE), is known to have a negative effect on the central nervous system in exposed human populations. However, the consequences of gestational exposure to DE on the fetal brain remain poorly explored, with various effects depending on the conditions of exposure, as well as little information on early developmental stages. We investigated the short-term effects of indirect DE exposure throughout gestation on the developing brain using a rabbit model. Read More

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https://particleandfibretoxicology.biomedcentral.com/article
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http://dx.doi.org/10.1186/s12989-018-0288-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335688PMC
January 2019
9 Reads

A modified reconstructive technique for paediatric congenital alar rim deformity.

Int J Pediatr Otorhinolaryngol 2019 Mar 29;118:201-205. Epub 2018 Dec 29.

Department of Plastic and Reconstructive Surgery, Great Ormond Street Hospital for Children, London, WC1N 3JH, UK.

Alar subunit retraction or notching whether acquired or congenital, can be challenging to reconstruct. Congenital cysts and benign lumps involving the nasal alar region can also result in acquired alar deformity once resected. Published reports describe different surgical methods, but we demonstrate a simple and highly satisfying technique. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01655876183064
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http://dx.doi.org/10.1016/j.ijporl.2018.12.034DOI Listing
March 2019
3 Reads

Cysteinyl leukotriene 1 receptor expression in nasal polyps.

Otolaryngol Pol 2018 Oct;72(6):17-22

Uniwersytet Medyczny w Białymstoku Klinika Otolaryngologii.

Cysteinyl leukotrienes (CysLTs) have been implicated in the pathogenesis of chronic rhinosinusitis (CRS). This study was undertaken to better understand the role of CysLTs in the development of CRS through 1). assessment of the pattern of expression of CysLT1 receptor in nasal polyps from patients with CRS and 2). Read More

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http://dx.doi.org/10.5604/01.3001.0012.5422DOI Listing
October 2018
1 Read

CD73 expression on effector T cells sustained by TGF-β facilitates tumor resistance to anti-4-1BB/CD137 therapy.

Nat Commun 2019 01 11;10(1):150. Epub 2019 Jan 11.

Department of Medicine-Division of Hematology/Oncology, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.

Agonist antibodies (Ab) directed against costimulatory molecules on the surface of antigen-primed T cells are in various stages of pre-clinical and clinical trials, albeit with limited therapeutic benefit as single agents. The underlying mechanisms of action remain incompletely understood. Here, we demonstrate an inhibitory role of ecto-enzyme CD73 for agonistic anti-4-1BB/CD137 Ab therapy. Read More

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http://www.nature.com/articles/s41467-018-08123-8
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http://dx.doi.org/10.1038/s41467-018-08123-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329764PMC
January 2019
5 Reads
10.742 Impact Factor

Three-Dimensional endoscopy: The future of nasoendoscopic training.

Laryngoscope 2019 Jan 9. Epub 2019 Jan 9.

Department of Ear, Nose and Throat (ENT) Surgery, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom.

Objectives/hypothesis: Three-dimensional (3D) endoscopy is an emerging tool in surgery that provides real-time depth perception. Its benefits have been investigated in surgical training, but the current literature lacks significant objective outcome data. We aimed to objectively compare the efficacy of two-dimensional (2D) versus 3D high-definition endoscopes in novice users. Read More

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http://doi.wiley.com/10.1002/lary.27812
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http://dx.doi.org/10.1002/lary.27812DOI Listing
January 2019
12 Reads

Lobar evenness of deposition/retention in rat lungs of inhaled silver nanoparticles: an approach for reducing animal use while maximizing endpoints.

Part Fibre Toxicol 2019 01 7;16(1). Epub 2019 Jan 7.

HCTm CO.,LTD, Seoicheon-ro 578 beon-gil, Majang-myeon, Icheon, 17383, South Korea.

Background: Information on particle deposition, retention and clearance are important for the evaluation of the risk of inhaled nanomaterials to human health. Recent revised OECD inhalation toxicity test guidelines require to evaluate the lung burden of nanomaterials after rodent subacute and subchronic inhalation exposure (OECD 412, OECD 413). These revised test guidelines require additional post-exposure observation (PEO) periods that include lung burden measurements that can inform on lung clearance behavior and translocation. Read More

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https://particleandfibretoxicology.biomedcentral.com/article
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http://dx.doi.org/10.1186/s12989-018-0286-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322301PMC
January 2019
9 Reads
7.113 Impact Factor

Endoscopic Two-port Technique for Infratemporal Fossa Tumors: Using Prelacrimal Medial Maxillectomy and Caldwell-Luc Approach.

World Neurosurg 2019 Jan 3. Epub 2019 Jan 3.

Department of Otorhinolaryngology - Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea. Electronic address:

Background: Endoscopic endonasal approach to infratemporal fossa (ITF) had gained popularity. However, the inferior turbinate and/or lacrimal duct are often removed when performing endoscopic medial maxillectomy for ITF approach and there were potential risk of empty nose syndrome or epiphora. Although endoscopic prelacrimal recess approach (EPRA) had been introduced to avoid these complications, there were some limitations associated with surgical freedom. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183295
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http://dx.doi.org/10.1016/j.wneu.2018.12.134DOI Listing
January 2019
9 Reads

Neuroprotective effect of insulin-loaded chitosan nanoparticles/PLGA-PEG-PLGA hydrogel on diabetic retinopathy in rats.

Int J Nanomedicine 2019 18;14:45-55. Epub 2018 Dec 18.

Department of Ophthalmology and The Eye Institute, Eye and Ear, Nose, and Throat Hospital, Fudan University, Shanghai, China,

Background: To pursuit effective sustained release systems for insulin to treat diabetic retinopathy (DR), a novel insulin delivering system was developed via loading onto chitosan nanoparticles/poly(lactic-co-glycolic acid)-poly(ethylene glycol)-poly(lactic-co-glycolic acid) hydrogel (ICNPH).

Methods And Materials: Examinations including electroretinography, HE staining, transmission electron microscopy, terminal deoxynucleotidyl transferased UTP nick-end labeling, immunofluorescence, Western blot, and real-time polymerase chain reaction were performed to evaluate the neuroprotective efficacy of ICNPH on DR by a single subconjunctival injection.

Results: Compared with the insulin, blank, and sham treatment groups, subconjunctival injection of ICNPH significantly reduced the decrease of scotopic B-wave amplitude, alleviated retinal micro- and ultrastructural changes, and reduced retinal cell apoptosis caused in DR rats. Read More

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http://dx.doi.org/10.2147/IJN.S184574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6302824PMC
February 2019
3 Reads

Clinical T staging is superior to fluorodeoxyglucose positron emission tomography for predicting local outcomes after intra-arterial infusion chemoradiotherapy for maxillary sinus squamous cell carcinoma.

Nagoya J Med Sci 2018 Nov;80(4):541-550

Department of Radiology, Hyogo College of Medicine, Nishinomiya, Japan.

Concomitant intra-arterial infusion chemoradiotherapy (IA-CRT) has been used to treat locally advanced maxillary sinus squamous cell carcinoma (MSSCC) with positive outcomes. However, an optimal predictive prognostic factor for MSSCC treated with IA-CRT remains elusive. The aim of the present study was to assess the feasibility of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET), including volumetric parameters, to predict the prognosis of MSSCC treated with IA-CRT. Read More

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http://dx.doi.org/10.18999/nagjms.80.4.541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295423PMC
November 2018
6 Reads

Treatment for active tuberculosis in giraffe (Giraffa camelopardalis) in a Zoo and potential consequences for public health - Case report.

Ann Agric Environ Med 2018 Dec 5;25(4):593-595. Epub 2017 Jul 5.

Department of Microbiology, National Veterinary Research Institute, Pulawy, Poland.

Introduction: Bovine tuberculosis (bTB) is an infectious disease that occurs in many species of both domestic and free-ranging animals, as well as animals kept in zoos. According to the Polish regulations, cattle tuberculosis are slaughtered and microbiological examinations are performed, the rest of animal species can be treated and laboratory diagnostics are not obligatory.

Case Report: The presented case concerns two male giraffes which were purchased by the zoo and united with a third male. Read More

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http://www.journalssystem.com/aaem/Treatment-for-active-tube
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http://dx.doi.org/10.26444/aaem/75685DOI Listing
December 2018
6 Reads

Candida auris otomycosis in Iran and review of recent literature.

Mycoses 2019 Feb;62(2):101-105

Department of Medical Mycology/Invasive Fungi Research Center (IFRC), School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Candida auris is a multidrug-resistant yeast emerging in immunocompromised and in otherwise healthy individuals. Due to difficulties in microbiological identification of C. auris because of the lack of available laboratory technology in developing countries, the number of patients affected is most likely underestimated. Read More

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http://dx.doi.org/10.1111/myc.12886DOI Listing
February 2019
1 Read
1.805 Impact Factor

Haemolacria in a 22-year-old boy.

BMJ Case Rep 2018 Dec 22;11(1). Epub 2018 Dec 22.

Departemnt of Anatomy, Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair, Andaman, India.

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22515
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http://dx.doi.org/10.1136/bcr-2018-225151DOI Listing
December 2018
8 Reads

Obstructive sleep apnea in children: How it affects parental psychological status?

Int J Pediatr Otorhinolaryngol 2019 Feb 30;117:157-162. Epub 2018 Nov 30.

Department of Nuclear Medicine, University Hospital Center Split, Croatia.

Purpose Of The Study: The aim of this study was to evaluate the influence of obstructive sleep apnea (OSA) in children on maternal and paternal anxiety.

Patients And Methods: This prospective study was conducted from January 2013 until January 2016 in the Ear, Nose and Throat (ENT) Department at the University Hospital of Split, Croatia. The parents of 59 children with a median age of 5 years (range: 2-9) who were suffering from obstructive sleep apnea (OSA) due to adenotonsillar hypertrophy were enrolled into the study. Read More

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http://dx.doi.org/10.1016/j.ijporl.2018.11.032DOI Listing
February 2019
2 Reads

Squamous cell carcinoma of the head and neck in children.

Int J Pediatr Otorhinolaryngol 2019 Feb 20;117:131-137. Epub 2018 Nov 20.

Department of Otolaryngology & Communication Enhancement, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, United States; Department of Otolaryngology, Harvard Medical School, 25 Shattuck St, Boston, MA, 02115, United States. Electronic address:

Objective: To discuss the presentation, evaluation, and management of squamous cell carcinoma of the head and neck in the pediatric population.

Methods: Medical records of pediatric (≤20 years) patients treated for squamous cell carcinoma of the head and neck between 1996 and 2016 were reviewed. Data pertaining to clinical presentation, diagnostic methods, treatment plan, complications, recurrence, follow-up, or outcome were collected. Read More

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http://dx.doi.org/10.1016/j.ijporl.2018.11.019DOI Listing
February 2019
1 Read

Latin Americans show wide-spread Converso ancestry and imprint of local Native ancestry on physical appearance.

Nat Commun 2018 12 19;9(1):5388. Epub 2018 Dec 19.

Ministry of Education Key Laboratory of Contemporary Anthropology and Collaborative Innovation Center of Genetics and Development, School of Life Sciences and Human Phenome Institute, Fudan University, Shanghai, 200433, China.

Historical records and genetic analyses indicate that Latin Americans trace their ancestry mainly to the intermixing (admixture) of Native Americans, Europeans and Sub-Saharan Africans. Using novel haplotype-based methods, here we infer sub-continental ancestry in over 6,500 Latin Americans and evaluate the impact of regional ancestry variation on physical appearance. We find that Native American ancestry components in Latin Americans correspond geographically to the present-day genetic structure of Native groups, and that sources of non-Native ancestry, and admixture timings, match documented migratory flows. Read More

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http://dx.doi.org/10.1038/s41467-018-07748-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300600PMC
December 2018
3 Reads
10.742 Impact Factor

A Safer Non-surgical Filler Augmentation Rhinoplasty Based on the Anatomy of the Nose.

Aesthetic Plast Surg 2019 Apr 17;43(2):447-452. Epub 2018 Dec 17.

Department of Plastic and Reconstructive Surgery, School of Medicine, Kyungpook National University, 130 Dongdeok-ro, Jung-gu, Daegu, 41944, Republic of Korea.

Background: Filler augmentation rhinoplasty is a quick, non-surgical procedure that can produce outcomes comparable to open rhinoplasty surgery. However, the increased frequency of vascular complications has emerged as an important issue. The present study aimed to investigate measures to overcome the vascular complications based on the anatomy of the nose. Read More

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http://link.springer.com/10.1007/s00266-018-1279-7
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http://dx.doi.org/10.1007/s00266-018-1279-7DOI Listing
April 2019
11 Reads

A morphometric study of the structures bordering the infra-cochlear corridor - Relevant for endoscopic/microscopic ear surgery.

J Otol 2018 Sep 18;13(3):81-84. Epub 2018 Aug 18.

Department of Ear Nose and Throat Surgery, The Alfred Hospital, Melbourne, Australia.

Application of surgical endoscope, used alone or in combination with the surgical microscope, for the operative management of ear and temporal bone conditions may allow improved access and clearance of disease. Preservation of normal structures may also be improved. As the use of this tool is increasing, the need for better understanding of the anatomy of the ear is becoming evident. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S16722930183005
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http://dx.doi.org/10.1016/j.joto.2018.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291685PMC
September 2018
12 Reads

Fecal volatile organic compounds for early detection of colorectal cancer: where are we now?

J Cancer Res Clin Oncol 2019 Jan 15;145(1):223-234. Epub 2018 Dec 15.

Department of Gastroenterology and Hepatology, Amsterdam UMC, Vrije Universiteit Amsterdam, AG&M Research Institute, Amsterdam, The Netherlands.

Introduction: The fecal volatolome, which is composed of fecal volatile organic compounds (VOCs), seems to hold potential as non-invasive biomarker for the detection of colorectal cancer (CRC) and its precursor lesions advanced adenomas (AA). The potential of the fecal volatolome has been subject of various studies using either chemical analytical or pattern-recognition techniques. The available literature on the potential of the fecal volatolome as CRC and AA biomarker was reviewed. Read More

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http://link.springer.com/10.1007/s00432-018-2821-3
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http://dx.doi.org/10.1007/s00432-018-2821-3DOI Listing
January 2019
11 Reads

Probiotics Streptococcus salivarius 24SMB and Streptococcus oralis 89a interfere with biofilm formation of pathogens of the upper respiratory tract.

BMC Infect Dis 2018 Dec 13;18(1):653. Epub 2018 Dec 13.

Laboratory of Clinical Chemistry and Microbiology, IRCCS Orthopedic Institute Galeazzi, Milan, Italy.

Background: Infections of the ears, paranasal sinuses, nose and throat are very common and represent a serious issue for the healthcare system. Bacterial biofilms have been linked to upper respiratory tract infections and antibiotic resistance, raising serious concerns regarding the therapeutic management of such infections. In this context, novel strategies able to fight biofilms may be therapeutically beneficial and offer a valid alternative to conventional antimicrobials. Read More

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http://dx.doi.org/10.1186/s12879-018-3576-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292094PMC
December 2018
5 Reads

Analysis of the development of human foetal nasal turbinates using CBCT imaging.

Surg Radiol Anat 2019 Feb 6;41(2):209-219. Epub 2018 Dec 6.

Department of Anatomy, School of Life Dentistry at Tokyo, The Nippon Dental University, 1-9-20 Fujimi, Chiyoda-ku, Tokyo, 102-8159, Japan.

Purpose: The morphological structure of the nasal cavity (NC) is important for endoscopic surgical treatment. The location of nasal turbinates, including the superior turbinate (ST), middle turbinate (MT) and inferior turbinate (IT), are well presented during the formation of the human NC in cone beam CT (CBCT) images. There is a complex relationship between the nasal sinuses, the maxillary sinus (MS), ethmoidal sinus and sphenoid sinus, during formation of the NC structure at the morphological level. Read More

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http://dx.doi.org/10.1007/s00276-018-2145-7DOI Listing
February 2019
2 Reads

[Research progress in maxillary sinus mucosal disease associated with maxillary sinus floor lifting].

Zhonghua Kou Qiang Yi Xue Za Zhi 2018 Dec;53(12):849-853

Department of Prosthodontics, Hospital of Stomatology, College of Medicine, Zhejiang University, Hangzhou 310000, China.

Maxillary sinus augmentation is an effective procedure to gain bone height for implant placement in an atrophic posterior maxilla. But maxillary sinus diseases are prevalent in patients scheduled for sinus lift procedures. The presence of these diseases may increase the difficulties in performing the surgery and the risk of developing postoperative complications. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1002-0098.2018.12.012DOI Listing
December 2018
1 Read

[Expression of CD117, MITF and NAT10 and their prognostic values in sinonasal mucosal melanoma].

Zhonghua Bing Li Xue Za Zhi 2018 Dec;47(12):931-935

Department of Pathology, Eye, Ear, Nose and Throat Hospital, Fudan University, Shanghai 200031, China.

To investigate the correlation between the expression of CD117, MITF, NAT10 and clinical parameters in sinonasal mucosal melanoma (SNMM). Formalin-fixed paraffin-embedded tumor specimens of 80 cases of SNMM at the Eye, Ear, Nose and Throat Hospital, Fudan University, from December 1999 to November 2013 were analyzed for CD117, MITF and NAT10 expression by immunohistochemistry. There were 40 men and 40 women. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-5807.2018.12.007DOI Listing
December 2018

Evaluation of bendable surgical suction devices made of shape-memory alloy for the endonasal transsphenoid removal of pituitary tumors.

Ear Nose Throat J 2018 Dec;97(12):413-416

Department of Medical Engineering, Fraunhofer Institute for Machine Tools and Forming Technology, Nöthnitzer Straße 44, 01187 Dresden, Germany.

In minimally invasive surgeries, it can be difficult to reach desired anatomic areas with rigid instruments, especially when obstacles are present in the surgical corridor (e.g., during transnasal pituitary surgery). Read More

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http://dx.doi.org/10.1177/014556131809701211DOI Listing
December 2018
1 Read

Comparisons of skin toxicity in patients with extranodal nasal-type natural killer/T-cell lymphoma after treatment with intensity-modulated radiotherapy and conventional radiotherapy.

J Cancer Res Ther 2018 Dec;14(Supplement):S975-S979

Department of Radiation Oncology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan Province 450052, P.R. China.

Background: Intensity-modulated radiation therapy (IMRT) has been more widely used in extranodal nasal-type natural killer/T-cell lymphoma (NKTCL) because it can maximally improve the local control rate of tumor and reduce the radiation dose received by surrounding normal tissues. However, there has been no consensus on whether IMRT can help to lower the toxic and adverse reactions caused by radiation therapy. The aim of this study is to compare skin toxicity caused by IMRT and conventional radiotherapy in Stage I-II NKTCL. Read More

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http://dx.doi.org/10.4103/0973-1482.192791DOI Listing
December 2018
2 Reads