387 results match your criteria Normal and Abnormal Puerperium


Relationship between non-alcoholic fatty liver disease during pregnancy and abnormal glucose metabolism during and after pregnancy.

J Investig Med 2020 Mar 17;68(3):743-747. Epub 2019 Dec 17.

Endocrinology, Diabetes, and Metabolism, University of Florida College of Medicine, Gainesville, Florida, USA.

While non-alcoholic fatty liver disease (NAFLD) is associated with increased risk of impaired glucose tolerance and type 2 diabetes mellitus (DM) in non-pregnant patients, the clinical significance of NAFLD during pregnancy is still unclear. We hypothesized that sonographic findings of NAFLD during pregnancy would be associated with gestational diabetes mellitus (GDM) and predict abnormal postpartum glucose metabolism. NAFLD was assessed by ultrasound during and after pregnancy. Read More

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http://dx.doi.org/10.1136/jim-2019-001186DOI Listing

Associations between postpartum phenotypes, cow factors, genetic traits, and reproductive performance in seasonal-calving, pasture-based lactating dairy cows.

J Dairy Sci 2020 Jan 20;103(1):1016-1030. Epub 2019 Nov 20.

Animal and Grassland Research and Innovation Centre, Teagasc, Moorepark, Fermoy, Co. Cork, Ireland, P61 C996. Electronic address:

The objective of this study was to evaluate associations between corpus luteum (CL) status, uterine health, body condition score (BCS), metabolic status, parity, genetic merit for fertility traits, and reproductive performance in pasture-based dairy cows managed for seasonal reproduction. First- and second-lactation (n = 2,600) spring-calving dairy cows from 35 dairy farms located in Ireland were enrolled in the study. Farms were visited every 2 wk, and animals that were at wk 3 (range: 14-27 d in milk) and wk 7 (range: 42-55 d in milk) postpartum were examined. Read More

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http://dx.doi.org/10.3168/jds.2018-16001DOI Listing
January 2020

Measurement of lipid profiles in the early postpartum period after hypertensive disorders of pregnancy.

J Clin Lipidol 2019 Nov - Dec;13(6):1008-1015. Epub 2019 Oct 12.

Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta, Canada; Department of Medicine, University of Calgary, Calgary, Alberta, Canada; Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada; O'Brien Institute for Public Health, University of Calgary, Calgary, Alberta, Canada; Department of Obstetrics & Gynecology, University of Calgary, Calgary, Alberta, Canada. Electronic address:

Background: The hypertensive disorders of pregnancy (HDP), including preeclampsia (PE) and gestational hypertension (GHTN), are independent risk factors for future maternal cardiovascular disease. Epidemiologic evidence has demonstrated that women with HDP have abnormal cardiovascular risk factors in the early postpartum period, but this has not been fully characterized.

Objective: This study aimed to assess the lipid profiles among women with PE, GHTN, and normal blood pressure in the first 4 years postpartum. Read More

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http://dx.doi.org/10.1016/j.jacl.2019.10.002DOI Listing
October 2019

Abnormal IL-10 levels were related to alanine aminotransferase abnormalities during postpartum in HBeAg positive women with chronic hepatitis B.

Medicine (Baltimore) 2019 Nov;98(46):e17969

Department of Obstetrics and Gynecology, Beijing YouAn Hospital.

Alanine transaminase (ALT) abnormalities are common in chronic hepatitis B (CHB) carriers during postpartum period. Disturbances in cytokines are considered to be associated with hepatitis Flares. There are limited data on cytokines changes in HBeAg positive patients with ALT abnormalities. Read More

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http://dx.doi.org/10.1097/MD.0000000000017969DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6867749PMC
November 2019

Associations between postpartum fertility phenotypes and genetic traits in seasonal-calving, pasture-based lactating dairy cows.

J Dairy Sci 2020 Jan 31;103(1):1002-1015. Epub 2019 Oct 31.

Animal and Grassland Research and Innovation Centre, Teagasc, Moorepark, Fermoy, Co. Cork, Ireland, P61 C996. Electronic address:

The objective of this study was to evaluate the associations between corpus luteum (CL) status, uterine health, body condition score (BCS), metabolic status, and parity at wk 3 and 7 postpartum in seasonal-calving, pasture-based, lactating dairy cows. The associations between those phenotypes and individual genetic traits were also evaluated. First- and second-parity spring-calving lactating dairy cows (n = 2,600) from 35 dairy farms in Ireland were enrolled. Read More

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http://dx.doi.org/10.3168/jds.2018-16000DOI Listing
January 2020

The experience of postpartum bleeding in women with inherited bleeding disorders.

Res Pract Thromb Haemost 2019 Oct 26;3(4):733-740. Epub 2019 Jul 26.

Department of Medicine University of Toronto Toronto Ontario Canada.

Introduction: Postpartum hemorrhage (PPH) affects 6% of all deliveries and is the leading cause of maternal death worldwide (19.7%). The incidence of PPH in women with inherited bleeding disorders is substantially greater than in unaffected women; however, estimates of relative risk are highly variable. Read More

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http://dx.doi.org/10.1002/rth2.12246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782019PMC
October 2019
2 Reads

[Pelvic floor function of 5 143 women in early postpartum stage and analysis on the effect factors].

Zhonghua Fu Chan Ke Za Zhi 2019 Aug;54(8):522-526

Department of Obstetrics and Gynecology, Peking University People's Hospital, Beijng Key Laboratory of Female Pelvic Floor Disorders, Beijing 100044, China, is working on the Department of Women's Health, Xicheng Women and Children's Health Hospital, Beijing 100054, China.

To describe the situation of early stage of pelvic floor function and investigate the effect factors in postpartum women. A retrospective survey was conducted, and women who did regular examination and gave birth in Peking University People's Hospital and had an annual pelvic floor examination at 6-12 weeks after delivery from Sep. 2012 to Dec. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0529-567x.2019.08.004DOI Listing
August 2019
2 Reads

Gestational Diabetes Mellitus Changes the Metabolomes of Human Colostrum, Transition Milk and Mature Milk.

Med Sci Monit 2019 Aug 16;25:6128-6152. Epub 2019 Aug 16.

Ministry of Education of China International Collaborative Joint Laboratory of Reproduction and Development, Chongqing Medical University, Chongqing, China (mainland).

BACKGROUND Gestational diabetes mellitus (GDM) is a pregnancy complication that is diagnosed by the novel onset of abnormal glucose intolerance. Our study aimed to investigate the changes in human breast milk metabolome over the first month of lactation and how GDM affects milk metabolome. MATERIAL AND METHODS Colostrum, transition milk, and mature milk samples from women with normal uncomplicated pregnancies (n=94) and women with GDM-complicated pregnancies (n=90) were subjected to metabolomic profiling by the use of gas chromatography-mass spectrometry (GC-MS). Read More

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http://dx.doi.org/10.12659/MSM.915827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708282PMC
August 2019
6 Reads

Risk factors for abnormal postpartum glucose outcome in women with gestational diabetes mellitus diagnosed by modified The International Association of the Diabetes and Pregnancy Study Groups criteria.

J Obstet Gynaecol Res 2019 Aug 10;45(8):1545-1552. Epub 2019 Jun 10.

Department of Obstetrics, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.

Aim: To characterize postpartum glycemic outcome and related risk factors in women diagnosed with gestational diabetes mellitus (GDM) by modified The International Association of the Diabetes and Pregnancy Study Groups (IADPSG) criteria.

Methods: This is a cohort study of 583 patients with GDM diagnosed by modified IADPSG criteria for Chinese women from 2016 to 2017. According to their oral glucose tolerance tests (OGTT) results at 6-12 weeks postpartum, the subjects were categorized into normal glucose tolerance (NGT) and abnormal glucose tolerance (AGT) groups using the World Health Organization criteria. Read More

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http://dx.doi.org/10.1111/jog.14009DOI Listing
August 2019
3 Reads

Invited review: A systematic review of the effects of prolonged cow-calf contact on behavior, welfare, and productivity.

J Dairy Sci 2019 Jul 15;102(7):5765-5783. Epub 2019 May 15.

Animal Welfare Program, Faculty of Land and Food Systems, University of British Columbia, Vancouver, BC, Canada V6T 1Z4. Electronic address:

Separation of calves from cows within hours or days of birth is common on dairy farms. Stakeholders have conflicting perspectives on whether this practice is harmful or beneficial for the animals' welfare and production. Our objective was to critically evaluate the scientific evidence for both acute and long-term effects of early separation versus an extended period of cow-calf contact. Read More

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http://dx.doi.org/10.3168/jds.2018-16021DOI Listing
July 2019
7 Reads

Multidetector CT appearance of the pelvis after vaginal delivery: normal appearances and abnormal acute findings.

Diagn Interv Radiol 2019 May;25(3):210-218

Department of Radiological Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Roma, Italy; Department of Radiological Sciences, Università Cattolica del Sacro Cuore, Roma, Italy.

Vaginal delivery is the most commonly performed delivery in the world and accounts for nearly two-thirds of all deliveries in the United States. It is a secure method but may be associated with some acute complications, especially in the immediate postpartum days, which can potentially be fatal for the mother. The most frequent acute complications are hemorrhages/hematomas, uterine rupture, endometritis, retained product of conception (RPOC), ovarian thrombosis and HELLP syndrome (hemolysis, elevated liver enzymes, low platelet count). Read More

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http://www.dirjournal.org/eng/makale/2040/62/Full-Text
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http://dx.doi.org/10.5152/dir.2019.18127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521907PMC
May 2019
22 Reads

Macroscopic evaluation of the placenta of the alpaca (Vicugna pacos).

Reprod Domest Anim 2019 Jul 21;54(7):996-1002. Epub 2019 May 21.

Faculty Veterinary Medicine, Department of Reproduction, Obstetrics and Herd Health, Ghent University, Merelbeke, Belgium.

Macroscopic evaluation of the placenta is an essential post-partum examination in the alpaca and can be of special interest in case of abortion, premature birth or stillbirth. Since there are not many reference values regarding macroscopic properties of normal alpaca placentas, a small descriptive study was conducted. Only placentae from normally foaling alpaca mares, giving birth to healthy crias, after a full-term and uneventful gestation (±350 days; range 335-360 days) were taken into account (N = 11). Read More

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http://dx.doi.org/10.1111/rda.13453DOI Listing
July 2019
3 Reads

Effect of postpartum glucose tolerance results on subsequent weight retention in women with recent gestational diabetes: A retrospective cohort study.

Diabetes Res Clin Pract 2019 May 18;151:169-176. Epub 2019 Apr 18.

Women's College Research Institute, Women's College Hospital, Toronto, Canada; Institute of Health Policy, Management and Evaluation/Dalla Lana School of Public Health, University of Toronto, Toronto, Canada; Department of Medicine, University of Toronto, Toronto, Canada; Institute for Clinical Evaluative Sciences, Toronto, Canada; Sunnybrook Health Sciences Centre, Toronto, Canada. Electronic address:

Aims: Glucose tolerance normalizes postpartum in most women with gestational diabetes (GDM), which may provide false reassurance and decrease weight-reducing behaviours. We evaluated whether awareness of normal postpartum glucose tolerance was associated with higher weight retention than being unaware of glucose tolerance.

Methods: This cohort study of women with GDM collected survey data during pregnancy and in the first and second postpartum year. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01688227193013
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http://dx.doi.org/10.1016/j.diabres.2019.04.016DOI Listing
May 2019
11 Reads

Negatively controlled, randomized clinical trial to evaluate intramammary treatment of nonsevere, gram-negative clinical mastitis.

J Dairy Sci 2019 Jun 10;102(6):5438-5457. Epub 2019 Apr 10.

Department of Animal Science, Michigan State University, East Lansing 48864. Electronic address:

The objective of this negatively controlled, randomized clinical trial was to examine clinical outcomes of 2-d or 8-d treatment using an approved intramammary (IMM) product containing ceftiofur hydrochloride compared with no antimicrobial treatment of nonsevere, gram-negative cases of clinical mastitis (CM). Additionally, we contrasted clinical outcomes of cases caused by Escherichia coli (n = 56) or Klebsiella pneumoniae (n = 54). Cases (n = 168) of nonsevere (abnormal milk or abnormal milk and udder) CM were randomly assigned to receive 2 d (n = 56) or 8 d (n = 56) of IMM ceftiofur or assigned to a negative control group (n = 56). Read More

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http://dx.doi.org/10.3168/jds.2018-16156DOI Listing
June 2019
4 Reads

[Impact of cessation of antiviral therapy at delivery on postpartum liver function in mothers with chronic hepatitis B virus infection].

Zhonghua Gan Zang Bing Za Zhi 2019 Feb;27(2):112-117

Department of Epidemiology, School of Public Health, Southern Medical University, Guangzhou 510515, China; Department of Hospital Infection Management, Zhujiang Hospital, Southern Medical University, Guangzhou 510220, China.

To investigate the impact of immediate cessation of antiviral therapy on postpartum liver function and the factors influencing postpartum abnormality in mothers with chronic hepatitis B virus infection. A retrospective cohort study was conducted. One hundred eighty-eight pregnant women with HBV DNA level > 2×106 IU/ml were enrolled from June 2014 to June 2018. Read More

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http://dx.doi.org/10.3760/cma.j.issn.1007-3418.2019.02.008DOI Listing
February 2019
11 Reads

Angiogenic Factor Estimation as a Warning Sign of Preeclampsia-Related Peripartum Morbidity Among Hospitalized Patients.

Hypertension 2019 04;73(4):868-877

From the Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology (J.L.P., S.C., A.M., R.M., H.R., R.N., H.N., D.Y., S.S., S.R.), University of Chicago, IL.

Preeclampsia-related morbidity and mortality is rising predominantly because of delayed identification of patients at risk for preeclampsia with severe features and associated complications. This study explored the association between angiogenic markers (sFlt1 [soluble fms-like tyrosine kinase-1]) and PlGF [placental growth factor]) and preeclampsia-related peripartum complications. Normotensive women or those with hypertensive disorders of pregnancy were enrolled. Read More

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12205DOI Listing
April 2019
11 Reads
6.480 Impact Factor

Dietary calcium status during maternal pregnancy and lactation affects lipid metabolism in mouse offspring.

Sci Rep 2018 11 8;8(1):16542. Epub 2018 Nov 8.

Laboratory of Nutrition, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.

Calcium plays important roles in lipid metabolism and adipogenesis, but whether its status in early life affects later lipid profiles needs to be clarified. Three to four-week old C57BL/6J female mice were fed with three different reproductive diets containing normal, low (insufficient) and high (excessive) calcium concentrations respectively throughout pregnancy and lactation. At postnatal 21 days, the weaning male and female pups from each group were sacrificed for experiments and the remaining were fed with the normal chow diet for 16 weeks. Read More

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http://www.nature.com/articles/s41598-018-34520-6
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http://dx.doi.org/10.1038/s41598-018-34520-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224457PMC
November 2018
5 Reads

Associations between the general condition of culled dairy cows and selling price at Ontario auction markets.

J Dairy Sci 2018 Nov 7;101(11):10580-10588. Epub 2018 Sep 7.

Department of Population Medicine, University of Guelph, Guelph, ON, N1G 2W1, Canada; Campbell Centre for the Study of Animal Welfare, University of Guelph, Guelph, ON, N1G 2W1, Canada. Electronic address:

Dairy cows are culled from the herd for a variety of reasons, the most common being fertility problems, low milk production, or udder problems. Disease and injury can contribute to the decision to cull either directly, or indirectly, by causing fertility or production problems, leading to culling. Disease or injury may also affect the cow's ability to handle the stress of transportation and may increase the risk for reduced welfare. Read More

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http://dx.doi.org/10.3168/jds.2018-14519DOI Listing
November 2018
9 Reads

Postpartum assessment of the beta cell function and insulin resistance for Chinese women with previous gestational diabetes mellitus.

Gynecol Endocrinol 2019 Feb 5;35(2):174-178. Epub 2018 Sep 5.

a Department of Endocrinology and Metabolism , Shanghai General Hospital Shanghai Jiao Tong University , Shanghai , China.

Gestational diabetes mellitus (GDM) imparts a high risk of developing postpartum diabetes and is considered to be an early stage of type 2 diabetes mellitus (T2DM). In this study, a 75-g oral glucose tolerance test was performed on 472 women with GDM at 6-8 weeks after delivery. The clinical and metabolic characteristics were compared between the patients with normal glucose tolerance (NGT) and abnormal glucose metabolism (AGM). Read More

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https://www.tandfonline.com/doi/full/10.1080/09513590.2018.1
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http://dx.doi.org/10.1080/09513590.2018.1512094DOI Listing
February 2019
11 Reads

Transfusion Medicine in a Multidisciplinary Approach to Morbidly Adherent Placenta: Preparing for and Preventing the Worst.

Transfus Med Rev 2018 10 27;32(4):244-248. Epub 2018 Jun 27.

Department of Pathology and Cell Biology, Columbia University Medical Center and New York-Presbyterian Hospital, New York, NY. Electronic address:

The increasing incidence of placenta accreta has paralleled the rise in its greatest risk factor: cesarean delivery. In placenta accreta, the abnormal invasion of the chorionic villi into the myometrium prevents separation of the placenta at delivery, and the myometrium is unable to contract to prevent hemorrhage. Spontaneous uterine rupture and hemoperitoneum may also occur in the setting of placenta percreta. Read More

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http://dx.doi.org/10.1016/j.tmrv.2018.05.007DOI Listing
October 2018
20 Reads
2.923 Impact Factor

Abdominal computed tomography (CT) scan in the evaluation of refractory puerperal fever: impact on management.

J Matern Fetal Neonatal Med 2020 Feb 6;33(4):577-582. Epub 2018 Sep 6.

Department of Obstetrics, Gynecology and Reproductive sciences, Chaim Sheba Medical Center, Tel Hashomer, Sackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel.

Computed tomography (CT) imaging should be employed judiciously, given its cost, use of intravenous contrast, and ionizing radiation. The aim of this study was to determine the clinical benefit of a CT scan in the evaluation of refractory puerperal fever and to identify the appropriate candidates for its use. This was a retrospective cohort study conducted in a single tertiary care center between January 2007 to April 2017. Read More

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http://dx.doi.org/10.1080/14767058.2018.1497603DOI Listing
February 2020
54 Reads

Changes Over Time in Hepatic Markers Predict Changes in Insulin Sensitivity, β-Cell Function, and Glycemia.

J Clin Endocrinol Metab 2018 07;103(7):2651-2659

Leadership Sinai Centre for Diabetes, Mount Sinai Hospital, Toronto, Ontario, Canada.

Context: Serum concentrations of liver enzymes and the hepatokine fetuin-A have been linked to the risk of type 2 diabetes, but their longitudinal impact on insulin resistance and β-cell dysfunction is unclear.

Objective: To evaluate the impact of changes over 2 years in fetuin-A and the liver enzymes alanine aminotransferase (ALT), aspartate aminotransferase (AST), and γ-glutamyltransferase (GGT) on changes in insulin sensitivity, β-cell function, and glycemia in women with varying degrees of previous gestational dysglycemia, reflecting a range of future diabetic risk.

Design/setting/participants: In total, 336 women underwent glucose challenge test (GCT) and oral glucose tolerance test (OGTT) in pregnancy, followed by repeat OGTT and measurement of ALT/AST/GGT/fetuin-A at both 1 year and 3 years postpartum. Read More

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http://dx.doi.org/10.1210/jc.2018-00306DOI Listing
July 2018
15 Reads

Previous Gestational Diabetes Increases Atherogenic Dyslipidemia in Subsequent Pregnancy and Postpartum.

Lipids 2018 04 6;53(4):387-392. Epub 2018 May 6.

Department of Medicine, Universitat Autònoma de Barcelona, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain.

In a cohort of women with previous gestational diabetes mellitus (GDM), we aimed to ascertain whether women with abnormal glucose tolerance 1-year postdelivery had a more atherogenic lipid profile during and after pregnancy than those with normal glucose tolerance. A prospective cohort study with longitudinal design between January 2004 and March 2016 was conducted. Three hundred and six (56. Read More

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http://dx.doi.org/10.1002/lipd.12040DOI Listing
April 2018
13 Reads

Biotin and pantothenic acid oversupplementation to conditional SLC5A6 KO mice prevents the development of intestinal mucosal abnormalities and growth defects.

Am J Physiol Cell Physiol 2018 07 18;315(1):C73-C79. Epub 2018 Apr 18.

Department of Medical Research, VA Medical Center , Long Beach, California.

Intestinal absorption of the water-soluble vitamins biotin and pantothenic acid is carrier mediated and involves the sodium-dependent multivitamin transporter (SMVT; product of the SLC5A6 gene). We recently observed that intestinal-specific (conditional) knockout of the mouse Slc5a6 gene (SMVT-cKO) is associated with growth retardation, the development of spontaneous and severe inflammation, abnormal histology in the large intestine, altered gut permeability, and early death. Our aim in this study was to examine the possibility that biotin and pantothenic acid oversupplementation (BPS) of the SMVT-cKO mice could reverse the above-described abnormalities. Read More

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http://dx.doi.org/10.1152/ajpcell.00319.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6087731PMC
July 2018
11 Reads

Natural History of Squamous Intraepithelial Lesions in Pregnancy and Mode of Delivery.

Anticancer Res 2018 04;38(4):2439-2442

Department of Obstetrics and Gynecology, General Hospital Vienna, Medical University Vienna, Vienna, Austria

Background: Numerous studies have addressed the impact of mode of delivery on the natural history of squamous intraepithelial lesions (SIL) in pregnant women. However, the literature is still contradictory.

Patients And Methods: In the course of a retrospective analysis, data of 63 pregnant women with abnormal cervical smears who were referred to our Outpatient Department for pre-invasive lesions of the cervix were analyzed. Read More

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http://ar.iiarjournals.org/content/38/4/2439.abstract
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http://dx.doi.org/10.21873/anticanres.12496DOI Listing
April 2018
19 Reads

The characteristics and predictors of postpartum hepatitis flares in women with chronic hepatitis B.

Am J Gastroenterol 2018 05 27;113(5):686-693. Epub 2018 Feb 27.

Department of Obstetrics and Gynecology, Beijing Ditan Hospital, Capital Medical University, Beijing, China. Division of Gastroenterology and Hepatology, Department of Medicine, NYU Langone Health, New York University School of Medicine, New York, NY, USA. Liver Diseases Center, Beijing Ditan Hospital, Capital Medical University, Beijing, China. Department of Biostatistics, Beijing Ditan Hospital, Capital Medical University, Beijing, China. Information Center, Beijing Ditan Hospital, Capital Medical University, Beijing, China. Department of Gynecology and Obstetrics, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China. W Yi and CQ Pan contributed equally to this work.

Introduction: We aimed to characterize postpartum disease flares among treatment-naive mothers with chronic hepatitis B (CHB). CHB mothers were enrolled and compared with non-infected mothers in terms of postpartum alanine aminotransferase (ALT) abnormalities.

Methods: Demographic, virological, and biochemical parameters were collected up to postpartum week 16, with flares and exacerbations defined as ALT levels 5-10 and >10 times the upper limit of normal, respectively. Read More

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http://dx.doi.org/10.1038/s41395-018-0010-2DOI Listing
May 2018
47 Reads

Electromyographic characterisation of abdominal wall trigger points developed after caesarean section and response to local anaesthesia: an observational study.

BJOG 2018 Sep 15;125(10):1313-1318. Epub 2018 Apr 15.

Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, Brazil.

Objective: This study examines the electromyography pattern of abdominal trigger points developed after a caesarean section, and the association between clinical response and local anaesthetic injection.

Design: Prospective cohort study.

Setting: A tertiary university hospital. Read More

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http://dx.doi.org/10.1111/1471-0528.15204DOI Listing
September 2018
23 Reads

SULFATION PATHWAYS: The steroid sulfate axis and its relationship to maternal behaviour and mental health.

Authors:
William Davies

J Mol Endocrinol 2018 08 13;61(2):T199-T210. Epub 2018 Feb 13.

School of PsychologyCardiff University, Cardiff, UK

Steroid hormones can exist in functionally dissociable sulfated and non-sulfated (free) forms and can exert profound effects on numerous aspects of mammalian physiology; the ratio of free-to-sulfated steroids is governed by the antagonistic actions of steroid sulfatase (STS) and sulfotransferase (SULT) enzymes. Here, I examine evidence from human and animal model studies, which suggests that STS and its major substrate (dehydroepiandrosterone sulfate, DHEAS) and product (DHEA) can influence brain function, behaviour and mental health, before summarising how the activity of this axis varies throughout mammalian pregnancy and the postpartum period. I then consider how the steroid sulfate axis might impact upon normal maternal behaviour and how its dysfunction might contribute towards risk of postpartum psychiatric illness. Read More

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http://dx.doi.org/10.1530/JME-17-0219DOI Listing
August 2018
8 Reads

Establishing blood gas ranges in healthy bovine neonates differentiated by age, sex, and breed type.

J Dairy Sci 2018 Apr 2;101(4):3205-3212. Epub 2018 Feb 2.

Department of Biological and Pharmaceutical Sciences, Institute of Technology Tralee, Tralee, Co. Kerry, Ireland, V92 CX88. Electronic address:

Calf mortality and morbidity commonly occurs within the first month of life postpartum. Standard health ranges are invaluable aids in diagnostic veterinary medicine to confirm normal or the degree and nature of abnormal parameters in (sub)clinically ill animals. Extensive research has indicated significant differences between the physiologies of neonate and adult cattle, particularly for blood parameters such as pH, base excess, anion gap, and bicarbonate (HCO). Read More

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http://dx.doi.org/10.3168/jds.2017-13445DOI Listing
April 2018
19 Reads

Postpartum computed tomography angiography of the fetoplacental macrovasculature in normal pregnancies and in those complicated by fetal growth restriction.

Acta Obstet Gynecol Scand 2018 Mar;97(3):322-329

Department of Obstetrics and Gynecology, Aalborg University Hospital, Aalborg, Denmark.

Introduction: Current knowledge of the fetoplacental vasculature in fetal growth restriction (FGR) due to placental dysfunction focuses on the microvasculature rather than the macrovasculature. The aim of this study was to investigate the feasibility of computed tomography angiography to analyze the fetoplacental macrovasculature in normal and FGR pregnancies.

Material And Methods: We included 29 placentas (22-42 weeks of gestation) from normal birthweight pregnancies and eight placentas (26-37 weeks of gestation) from FGR pregnancies (birthweight < -15% and abnormal umbilical Doppler flow). Read More

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http://dx.doi.org/10.1111/aogs.13289DOI Listing
March 2018
15 Reads

Inability to suppress the stress-induced activation of the HPA axis during the peripartum period engenders deficits in postpartum behaviors in mice.

Psychoneuroendocrinology 2018 04 21;90:182-193. Epub 2017 Dec 21.

Tufts University School of Medicine, Department of Neuroscience, Boston, MA 02111, United States. Electronic address:

The stress-induced activation of the hypothalamic-pituitary-adrenal (HPA) axis is normally suppressed during pregnancy. Dysregulation of the HPA axis has been proposed to play a role in postpartum depression. However, direct investigation into the relationship between the HPA axis and postpartum depression has been hindered by the lack of useful animal models. Read More

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http://dx.doi.org/10.1016/j.psyneuen.2017.12.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6613202PMC
April 2018
11 Reads

Is unplanned out-of-hospital birth managed by paramedics 'infrequent', 'normal' and 'uncomplicated'?

BMC Pregnancy Childbirth 2017 12 22;17(1):436. Epub 2017 Dec 22.

University of the Sunshine Coast, ML40, Locked bag 4, Maroochydore DC, Qld, 4558, Australia.

Background: Unplanned out-of-hospital birth is often perceived as precipitate in nature, 'infrequent', 'normal' and 'uncomplicated'. However, international studies report unplanned out-of-hospital birth is associated with increased rates of maternal and neonatal morbidity and mortality. This research describes intrapartum, immediate postpartum and neonatal care provided by paramedics in Queensland, Australia. Read More

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http://dx.doi.org/10.1186/s12884-017-1617-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741876PMC
December 2017
13 Reads

Circulating B-type natriuretic peptide in women with and without recent gestational diabetes: The impact of current glucose intolerance.

Clin Endocrinol (Oxf) 2018 02 27;88(2):227-233. Epub 2017 Nov 27.

Leadership Sinai Centre for Diabetes, Mount Sinai Hospital, Toronto, Canada.

Context: Circulating B-type natriuretic peptide, as measured by the N-terminal fragment of its prohormone (NT-proBNP), is inversely associated with incident type 2 diabetes (T2DM) but positively related to future cardiovascular disease (CVD). Recognizing that gestational diabetes (GDM) identifies women at future risk for both T2DM and CVD, we sought to determine whether gestational glucose tolerance relates to NT-proBNP in the years after delivery.

Design/patients/measurements: Three hundred and forty women underwent a glucose challenge test (GCT) and an oral glucose tolerance test (OGTT) in pregnancy, yielding 4 gestational glucose tolerance groups: GDM (n = 105); gestational impaired glucose tolerance (n = 59); abnormal GCT with a normal OGTT (n = 98); and normal GCT with normal OGTT (n = 75). Read More

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http://dx.doi.org/10.1111/cen.13510DOI Listing
February 2018
23 Reads

Abnormal 1-hour post-load glycemia during pregnancy impairs post-partum metabolic status: a single-center experience.

J Endocrinol Invest 2018 May 24;41(5):567-573. Epub 2017 Oct 24.

Endocrinology Section, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Hospital, University of Catania, via Palermo 636, 95122, Catania, Italy.

Purpose: Recent evidence indicates that people with normal glucose tolerance (NGT) but 1-h post-load plasma glucose (1-h OGTT) ≥ 155 mg/dl have an increased risk for developing Type 2 diabetes mellitus (T2DM), determining a new risk category with deeper metabolic impairment. The aim of this study was to identify, among women with gestational diabetes (GDM), which alterations at OGTT during pregnancy are more frequently associated with 1-h OGTT ≥ 155 mg/dl at post-partum examination.

Methods: Among 297 women affected by GDM, we retrospectively evaluated 244 resulted NGT after delivery. Read More

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http://dx.doi.org/10.1007/s40618-017-0774-zDOI Listing
May 2018
6 Reads

Postpartum Retained Products of Conception: A Novel Approach to Follow-Up and Early Diagnosis.

Ultraschall Med 2018 Dec 21;39(6):643-649. Epub 2017 Sep 21.

Obstetrics and Gynecology, Assaf Harofeh Medical Center, Tel Aviv University, Zerifin, Israel.

Purpose:  To investigate whether ultrasound follow-up for the detection of postpartum retained products of conception (RPOC) in women considered at risk for this condition may allow for early diagnosis.

Methods:  Parturients at risk for RPOC underwent an ultrasound exam on the second postpartum day. Based on the ultrasound findings, women were either: (1) discharged to routine postpartum care in cases of normal scans, (2) invited for follow-up in cases of abnormal scans. Read More

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http://dx.doi.org/10.1055/s-0043-113817DOI Listing
December 2018
48 Reads

Outcome of Pregnancy Related Acute Kidney Injury Observed in a Tertiary Care Hospital.

Mymensingh Med J 2017 07;26(3):463-470

Dr AK Saleh Uddin Ahammed, Assistant Professor, Department of Nephrology, MMC, Mymensingh, Bangladesh.

This prospective case control study was carried out in Mymensingh Medical College Hospital (MMCH) from April 2011 to March 2012. The main objective of the study was to determine the short term maternal outcome of pregnancy related Acute Kidney Injury and to identify aetiological factors and to observe clinical features of pregnancy related Acute Kidney Injury. Total 60 pregnant women with AKI were included in the study as sample and equal (60) number of pregnant women with normal renal function was taken as control. Read More

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July 2017
28 Reads

Pregnancy outcomes in patients with uterine fibroids treated with ultrasound-guided high-intensity focused ultrasound.

BJOG 2017 Aug;124 Suppl 3:30-35

Department of Obstetrics and Gynaecology of Chongqing Haifu Hospital, Chongqing, China.

Objective: To investigate the effect of high-intensity focused ultrasound (HIFU) ablation for uterine fibroids on pregnancy.

Design: A retrospective observational study.

Setting: Department of Gynaecology in a single centre in China. Read More

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http://dx.doi.org/10.1111/1471-0528.14742DOI Listing
August 2017
40 Reads

Relationships among early postpartum luteal activity, parity, and insemination outcomes based on in-line milk progesterone profiles in Canadian Holstein cows.

Theriogenology 2017 Sep 27;100:32-41. Epub 2017 May 27.

Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB T6G 2P5, Canada; Livestock Research & Extension Branch, Alberta Agriculture and Forestry, Edmonton, AB T6H 5T6, Canada. Electronic address:

The objectives of this retrospective study were to use in-line milk progesterone (mP4) data to investigate relationships of (1) commencement of luteal activity (CLA), and (2) luteal phase (LP) length and frequency preceding first postpartum AI, with parity and AI outcomes in Canadian Holstein cows. Starting 21 ± 1 days postpartum (DPP), levels of mP4 were assessed every 2.2 ± 2. Read More

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http://dx.doi.org/10.1016/j.theriogenology.2017.05.021DOI Listing
September 2017
9 Reads

Reference values for maternal total and differential leukocyte counts in different trimesters of pregnancy and the initial postpartum period in western Turkey.

J Obstet Gynaecol 2017 Jul 7;37(5):571-575. Epub 2017 Feb 7.

b Department of Gynecology and Obstetrics , Manisa Maternity and Child Hospital , Manisa , Turkey.

The aim of this study was to investigate alterations in the leukocyte and differential leukocyte counts in different trimesters of pregnancy and the initial postpartum period. The study population consisted of 40,325 pregnant women. A full blood count and automated differential leukocyte count were performed and all the haemogram results in the different trimesters of pregnancy were recorded. Read More

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http://dx.doi.org/10.1080/01443615.2016.1268575DOI Listing
July 2017
20 Reads
0.604 Impact Factor

Benefits of Cervical Cancer Screening by Liquid-Based Cytology as Part of Routine Antenatal Assessment.

Asian Pac J Cancer Prev 2016 ;17(9):4457-4461

Department of Obstetrics and Gynaecology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand E-mail :

Purpose: To determine the prevalence of abnormal cervical cytology, as diagnosed using a liquid-based cytology technique, in pregnant women attending the Antenatal Care (ANC) clinic at Siriraj Hospital.

Materials And Methods: This cross-sectional study included 655 first-visit pregnant women who attended ANC clinic at Siriraj Hospital during June to November 2015 study period. After receiving routine antenatal care, cervical cytology screening was performed with the Siriraj liquid-based cytology technique. Read More

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February 2017
21 Reads

Performance of the Obstetric Early Warning Score in critically ill patients for the prediction of maternal death.

Am J Obstet Gynecol 2017 Jan 15;216(1):58.e1-58.e8. Epub 2016 Oct 15.

Grupo de Investigación en Cuidados intensivos y Obstetricia (GRICIO), Departments of Obstetrics and Gynecology, Universidad de Cartagena, Barrio Alcibia, sector María Auxiliadora, Cartagena, Colombia; Internal Medicine, Universidad de Cartagena, Barrio Alcibia, sector María Auxiliadora, Cartagena, Colombia; Unidad de Cuidados Intensivos Gestión Salud, Barrio Alcibia, sector María Auxiliadora, Cartagena, Colombia.

Background: Every day, about 830 women die worldwide from preventable causes related to pregnancy and childbirth. Obstetric early warning scores have been proposed as a potential tool to reduce maternal morbidity and mortality, based on the identification of predetermined abnormal values in the vital signs or laboratory parameters, to generate a rapid and effective medical response. Several early warning scores have been developed for obstetrical patients, but the majority are the result of a clinical consensus rather than statistical analyses of clinical outcome measures (ie, maternal deaths). Read More

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http://dx.doi.org/10.1016/j.ajog.2016.09.103DOI Listing
January 2017
55 Reads
1 Citation
4.704 Impact Factor

Parturition effects on reproductive health in the gilt and sow.

Reprod Domest Anim 2016 Oct;51 Suppl 2:36-47

Department Production Animal Medicine, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.

In this review, we address significant characteristics of parturition in the pig and their connection to post-partum reproductive health and fertility. We discuss the normal physiology and behaviour around parturition and the effect of the second phase (expulsion of foetuses) on the third phase of parturition (expulsion of foetal membranes). In addition, we intend to cover retained placenta, and the connection to post-partum uterine health and fertility in the contemporary prolific sow. Read More

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http://doi.wiley.com/10.1111/rda.12798
Publisher Site
http://dx.doi.org/10.1111/rda.12798DOI Listing
October 2016
8 Reads

Amniotic Fluid Embolism.

MCN Am J Matern Child Nurs 2017 Jan/Feb;42(1):29-35

Courtney Stanley Sundin is a Clinical Nurse Supervisor at Labor & Delivery, Baylor Scott & White All Saints Medical Center, Andrews Women's Hospital, Fort Worth, TX. The author can be reached via e-mail at Lauren Bradham Mazac is a Clinical Nurse Supervisor at Labor & Delivery, Baylor Scott & White All Saints Medical Center, Andrews Women's Hospital, Fort Worth, TX.

Amniotic fluid embolism (AFE) is a rare but serious and potentially deadly complication of pregnancy that is unpreventable and unpredictable. Most AFE events occur during labor; however, approximately one third happen during the immediate postpartum period. Presentation is abrupt and thought to be an abnormal response to fetal materials entering maternal circulation through the placental insertion site. Read More

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http://dx.doi.org/10.1097/NMC.0000000000000292DOI Listing
April 2018
59 Reads

"Seeing Is Believing": Dermatoscope Facilitated Breast Examination of the Breastfeeding Woman with Nipple Pain.

Breastfeed Med 2016 09 17;11:356-60. Epub 2016 Aug 17.

4 Department of Physiology and Cell Biology, Faculty of Health Sciences, Ben-Gurion University of the Negev , Beer-Sheva, Israel .

Background: It is well recognized that breastmilk provides optimal nutrition and immunological protection for infants. Many women, however, experience nipple pain while breastfeeding, leading to premature cessation of nursing. To overcome these difficulties, timely diagnosis is crucial to effectively treat the underlying pathology and permit resumption of breastfeeding. Read More

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http://dx.doi.org/10.1089/bfm.2016.0051DOI Listing
September 2016
21 Reads

Abnormal glucose tolerance post-gestational diabetes mellitus as defined by the International Association of Diabetes and Pregnancy Study Groups criteria.

Eur J Endocrinol 2016 Oct 15;175(4):287-97. Epub 2016 Jul 15.

Galway Diabetes Research CentreNational University of Ireland, Galway, Ireland.

Objective: An increase in gestational diabetes mellitus (GDM) prevalence has been demonstrated across many countries with adoption of the International Association of the Diabetes and Pregnancy Study Groups (IADPSG) diagnostic criteria. Here, we determine the cumulative incidence of abnormal glucose tolerance among women with previous GDM, and identify clinical risk factors predicting this.

Design: Two hundred and seventy women with previous IADPSG-defined GDM were prospectively followed up for 5years (mean 2. Read More

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http://dx.doi.org/10.1530/EJE-15-1260DOI Listing
October 2016
49 Reads

Glucose Intolerance after a Recent History of Gestational Diabetes Based on the 2013 WHO Criteria.

PLoS One 2016 10;11(6):e0157272. Epub 2016 Jun 10.

Department of Endocrinology, UZ Gasthuisberg, KU Leuven, Leuven, Belgium.

Aims: Uncertainty exists on the prevalence of glucose intolerance in women with a recent diagnosis of gestational diabetes (GDM) based on a two-step screening strategy and the 2013 World Health Organization (WHO) criteria. Our aim was to evaluate the uptake of postpartum screening, the prevalence and the risk factors for glucose intolerance in women with a recent history of GDM.

Methods: Retrospective analysis of the medical records of women with a recent history of GDM diagnosed in a universal two-step screening strategy with the 2013 WHO criteria. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0157272PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4902304PMC
July 2017
42 Reads

Predictors of Abnormal Glucose Tolerance in the Early Postpartum Period in Patients with Gestational Diabetes.

Kurume Med J 2016 25;62(3-4):47-51. Epub 2016 May 25.

Department of Obstetrics and Gynecology, Kurume University School of Medicine.

This study was designed to investigate the clinical predictors of abnormal glucose tolerance 5-7 weeks after delivery. Subjects were 155 women diagnosed with gestational diabetes mellitus (GDM) between October 2005 and September 2013 whose pregnancy and delivery were managed at our center. Subjects were divided into a normal glucose tolerance group (NGT; n = 113), or abnormal glucose tolerance group (AGT; n = 42) with borderline or overt diabetes mellitus, based on 75-g oral glucose tolerance test (75 gOGTT) results 5-7 weeks after delivery. Read More

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http://dx.doi.org/10.2739/kurumemedj.MS65006DOI Listing
April 2017
25 Reads

Postpartum sacral stress fracture: a case report.

BMC Pregnancy Childbirth 2016 Apr 30;16:96. Epub 2016 Apr 30.

Department of Obstetrics and Gynecology, American University of Beirut Medical Center, PO Box: 11-0236, Riad El Solh, Beirut, 1107 2020, Beirut, Lebanon.

Background: Stress fractures are classified as insufficiency and fatigue fractures. Insufficiency fractures occur when normal stresses are placed on bone with decreased mineralization and elastic resistance; whereas fatigue fractures occur when abnormal forces are applied to normal bone.

Case Presentation: We report a case of postpartum bilateral sacral fracture in the absence of documented osteoporosis in a 30 year old Lebanese female, thus satisfying the classification of fatigue fractures. Read More

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http://dx.doi.org/10.1186/s12884-016-0873-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4852431PMC
April 2016
12 Reads

Early Postpartum Glucose Testing in Women with Gestational Diabetes Mellitus.

Am J Perinatol 2016 08 27;33(10):966-71. Epub 2016 Apr 27.

Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Objective Given that most women with gestational diabetes mellitus (GDM) never undergo the recommended 6 to 12 weeks postpartum glucose tolerance test (GTT), we assessed the feasibility of performing GTTs on postpartum day 2. Study Design Women with abnormal postpartum day 2 results were similar to women with normal postpartum day 2 results except that more women with abnormal results required medicine to treat their GDM (Table 1). [corrected]. Read More

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http://dx.doi.org/10.1055/s-0036-1583193DOI Listing
August 2016
17 Reads