7,989 results match your criteria Noninvasive Ventilation


Noninvasive Ventilation Use in Pediatric Status Asthmaticus.

J Asthma 2021 Jun 10:1-9. Epub 2021 Jun 10.

Department of Critical Care, New York-Presbyterian Morgan Stanley Children's Hospital.

Noninvasive ventilation (NIV) is sometimes used in refractory pediatric status asthmaticus for its potential benefits of stenting airways and dispersing albuterol. However, its effectiveness in pediatric asthma remains unproven. The usage pattern, outcomes, and safety of NIV in pediatric status asthmaticus are described. Read More

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Noninvasive Ventilation in Patients With COVID-19-Related Acute Hypoxemic Respiratory Failure: A Retrospective Cohort Study.

Front Med (Lausanne) 2021 24;8:638201. Epub 2021 May 24.

National Clinical Research Center for Infectious Disease, The Third People's Hospital of Shenzhen, The Second Affiliated Hospital of Southern University of Science and Technology, Shenzhen, China.

Noninvasive ventilation (NIV) has been used to alleviate hypoxemia and dyspnea, but there is no consensus on the application of NIV in patients with coronavirus disease 2019 (COVID-19). Some staff use NIV as the rescue therapy which might lead to the adverse outcomes. This study was to identify early factors associated with intubation to help the medical staff select appropriate patients for receiving NIV treatment. Read More

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Incidence of pneumomediastinum in COVID-19: A single-center comparison between 1st and 2nd wave.

Respir Investig 2021 May 28. Epub 2021 May 28.

Tor Vergata Polyclinic, Department of Surgery, Units of Thoracic Surgery and Breast Surgery, Floor 7A, Viale Oxford 81, 00133, Rome, Italy.

In this study, we compared the incidence of pneumomediastinum in coronavirus disease (COVID-19) patients during the ascending phases of the 1st and 2nd epidemic waves. Crude incidence was higher during the 2nd wave at a quasi-significant level (0.68/1000 vs. Read More

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Detection of acute ventilatory problems via magnetic induction in a newborn animal model.

Pediatr Res 2021 Jun 8. Epub 2021 Jun 8.

Department of Neonatology, University Children's Hospital, RWTH Aachen University, Aachen, Germany.

Background: Magnetic induction measurement (MIM) is a noninvasive method for the contactless registration of respiration in newborn piglets by using measurement coils positioned at the bottom of an incubator. Acute pulmonary problems may be determinants of poor neurological and psychomotor outcomes in preterm infants. The current study tested the detection of pulmonary ventilation disorders via MIM in 11 newborn piglets. Read More

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Effects of Mechanical Insufflation-Exsufflation on Sputum Volume in Mechanically Ventilated Critically Ill Subjects.

Respir Care 2021 Jun 8. Epub 2021 Jun 8.

Cardiac Surgery Critical Care Unit, Institut Clinic Cardiovascular, Hospital Clínic, Barcelona, Spain.

Background: Mechanical insufflation-exsufflation (MI-E) is a noninvasive technique performed to simulate cough and remove sputum from proximal airways. To date, the effects of MI-E on critically ill patients on invasive mechanical ventilation are not fully elucidated. In this randomized crossover trial, we evaluated the efficacy and safety of MI-E combined to expiratory rib cage compressions (ERCC). Read More

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SNAP: Supportive noninvasive ventilation for acute chest syndrome prevention in children with sickle cell disease.

Pediatr Blood Cancer 2021 Jun 8:e29136. Epub 2021 Jun 8.

Department of Pediatrics, Boston Medical Center, Boston, Massachusetts, USA.

Background: Acute chest syndrome (ACS) is a leading cause of morbidity and mortality among children with sickle cell disease (SCD). Preventing hypoxemia by optimizing lung aeration during sleep remains a challenge.

Objectives: To explore safety, feasibility, and tolerability of noninvasive, bi-level positive airway pressure ventilation (BiPAP) as preventative, supportive care for hospitalized, medically stable children with SCD on a general pediatric inpatient unit. Read More

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PICU Follow-Up Clinic: Patient and Family Outcomes 2 Months After Discharge.

Pediatr Crit Care Med 2021 Jun 8. Epub 2021 Jun 8.

Division of Pediatric Critical Care Medicine, Department of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montréal, QC, Canada. CHU Sainte-Justine Research Center, Montréal, QC, Canada. Department of Psychology, Université de Montréal, Montréal, QC, Canada.

Objectives: Hospitalization in a PICU is a life-altering experience for children and their families. Yet, little is known about the well-being of these children after their discharge. We are describing the outcome of PICU survivors at a PICU clinic 2 months after discharge. Read More

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Insights About Prone and Lateral Positioning in Spontaneously Breathing Patients With COVID-19 Pneumonia Undergoing Noninvasive Helmet CPAP Treatment.

Chest 2021 06;159(6):2506-2507

Dipartimento di Anestesia, Rianimazione, Terapia Intensiva e Scienze Tossicologiche, IRCCS Fondazione Policlinico A. Gemelli, Roma, Italy.

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Protective ventilation and outcomes of critically ill patients with COVID-19: a cohort study.

Ann Intensive Care 2021 Jun 7;11(1):92. Epub 2021 Jun 7.

Divisao de Pneumologia, Instituto Do Coracao, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, São Paulo, Brazil.

Background: Approximately 5% of COVID-19 patients develop respiratory failure and need ventilatory support, yet little is known about the impact of mechanical ventilation strategy in COVID-19. Our objective was to describe baseline characteristics, ventilatory parameters, and outcomes of critically ill patients in the largest referral center for COVID-19 in Sao Paulo, Brazil, during the first surge of the pandemic.

Methods: This cohort included COVID-19 patients admitted to the intensive care units (ICUs) of an academic hospital with 94 ICU beds, a number expanded to 300 during the pandemic as part of a state preparedness plan. Read More

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Enlarged pulmonary artery on computed tomography and respiratory failure in sickle cell disease acute chest syndrome.

Pulm Circ 2021 Apr-Jun;11(2):20458940211018345. Epub 2021 May 21.

Department of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, NY, USA.

Predicting the severity of acute chest syndrome is an important research priority in sickle cell disease. In this retrospective study of patients with acute chest syndrome, an enlarged pulmonary artery on computed tomography was associated with severe respiratory failure defined by the need for either noninvasive or mechanical ventilation. Read More

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A Retrospective Analysis of Outcome in Malaria Patients Admitted into a Multidisciplinary Intensive Care Unit of a Tertiary Care Teaching Hospital.

Anesth Essays Res 2020 Jul-Sep;14(3):425-427. Epub 2021 Mar 22.

Department of Critical Care Medicine, NRI Medical College, Guntur, Andhra Pradesh, India.

Introduction: Malaria is a significant public health problem with people worldwide at risk for the disease. It is a mosquito-borne disease causing high-grade fever, chills, and flu-like illness. The World Health Organization (WHO) recommends the case with severe malaria should be admitted in the intensive care unit (ICU). Read More

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Inflammatory Myopathy Associated with Anti-mitochondrial Antibody Presenting Only with Respiratory Failure.

Intern Med 2021 Jun 5. Epub 2021 Jun 5.

Department of Neurology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Japan.

A 56-year-old woman presenting with type II respiratory failure was transferred to our hospital. She did not exhibit muscle weakness or elevated serum myogenic enzymes, but needle electromyography revealed myogenic changes in the limb muscles, and her blood tests were positive for anti-mitochondrial antibodies (AMA). Muscle histopathological findings included immune-mediated necrotizing myopathy, so she was diagnosed with inflammatory myopathy associated with AMA. Read More

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The Intermittent Abdominal Pressure Ventilator as an alternative modality of noninvasive ventilatory support: a narrative review.

Am J Phys Med Rehabil 2021 May 28. Epub 2021 May 28.

Institute of Respiratory Disease, Department of Basic Medical Science, Neuroscience and Sensory Organs, University of Bari "Aldo Moro", Italy Pulmonary Rehabilitation Unit, Don Carlo Gnocchi Foundation, Milan, Italy Department of Physical Medicine and Rehabilitation, Rutgers University New Jersey Medical School, Newark, USA.

Abstract: Noninvasive ventilation has become the initial treatment for symptomatic ventilatory pump failure (VPF) but when used at ventilatory support settings can be an alternative to tracheostomy mechanical ventilation. The intermittent abdominal pressure ventilator (IAPV), a corset with an internal air sack inflated by a ventilator, allows to increase tidal volumes through the raising of the diaphragm and its consequent passive descent. It has been used for daytime support for over 70 years but its knowledge among clinicians is scarce. Read More

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Helmet and face mask for non-invasive respiratory support in patients with acute hypoxemic respiratory failure: A retrospective study.

J Crit Care 2021 May 29;65:56-61. Epub 2021 May 29.

Department of Medicine and Surgery, University of Milano-Bicocca, Via Cadore, 48, Monza 20900, MB, Italy.; Department of Anesthesia and Intensive Care Medicine, San Gerardo Hospital, ASST Monza, Monza e Brianza, Via G. B. Pergolesi, 33, Monza 20900, MB, Italy. Electronic address:

Purpose: Non-invasive respiratory support could reduce the incidence of intubation in patients with Acute Hypoxemic Respiratory Failure (AHRF). The optimal interface or modality of non-invasive respiratory support is debated. We sought to evaluate the differences between patients who succeeded or failed non-invasive respiratory support, with a specific focus on the type of non-invasive respiratory support (i. Read More

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Perioperative respiratory adverse events during ambulatory anesthesia in obese children.

Ir J Med Sci 2021 Jun 5. Epub 2021 Jun 5.

Department of Anesthesia, Klinikum Klagenfurt, Feschigstrasse 11, 9020, Klagenfurt, Austria.

Obesity is one of the most common clinical conditions in the pediatric population with an increasing prevalence ranging from 20 to 30% worldwide. It is well known that during ambulatory anesthesia, obese children are more prone to develop perioperative respiratory adverse events (PRAEs) associated with obesity. To avoid or at least minimize these adverse effects, a thorough preoperative assessment should be undertaken as well as consideration of specific anesthetic approaches such as preoxygenation before induction of anesthesia and optimizing drug dosing. Read More

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Noninvasive ventilation can modulate heart rate variability during high-intensity exercise in COPD-CHF patients.

Heart Lung 2021 Jun 1;50(5):609-614. Epub 2021 Jun 1.

Cardiopulmonary Physiotherapy Laboratory, Physiotherapy Department, Federal University of Sao Carlos, UFSCar, Rodovia Washington Luis, KM 235, Monjolinho, CEP: 13565-905, Sao Carlos, SP, Brazil. Electronic address:

Objective: to assess the acute effects of non-invasive ventilation (NIV) during high-intensity exercise on heart rate variability (HRV) responses in chronic obstructive pulmonary disease (COPD) and Chronic heart failure (CHF) patients.

Methods: This was randomized, double blinded and controlled study. Fourteen patients with COPD-HF diagnosis were evaluated. Read More

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Noninvasive ventilation for respiratory distress syndrome is a potential risk factor for retinopathy of prematurity : Single Slovenian tertiary center study.

Wien Klin Wochenschr 2021 Jun 3. Epub 2021 Jun 3.

Neonatal Intensive Care Unit, Department of Perinatology, Division of Gynecology and Obstetrics, University Medical Centre Ljubljana, Šlajmerjeva 4, 1000, Ljubljana, Slovenia.

Retinopathy of prematurity (nROP) among extremely low gestational age newborns (ELGAN) in Slovenia has increased in recent years. At the same time mortality has further decreased and less invasive approaches for treatment of respiratory distress syndrome have been established. With the aim to study the possible association between the incidence of ROP and the duration of noninvasive ventilation, this retrospective study comprised ELGANs born during the first period (2010/2011), when invasive respiratory support was the prevalent method and in the second period (2015/2016), when noninvasive respiratory support was adopted. Read More

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Severe coronavirus disease pneumonia in pediatric patients in a referral hospital.

J Trop Pediatr 2021 Jun 3. Epub 2021 Jun 3.

Department of Pediatric Infectious Disease, Ankara City Hospital Ankara, Turkey.

Objective: We aimed to evaluate the characteristics and outcomes of critically ill children managed in an intensive care unit because of coronavirus disease (COVID-19) pneumonia with respiratory support requirements.

Methods: We performed a single-center retrospective observational study in a pediatric intensive care unit (PICU) with 32 beds in Ankara City Hospital, Ankara, Turkey, from March 13, 2020, to December 31, 2020. Patients who needed positive-pressure ventilation (PPV) therapy for COVID-19 pneumonia were included in the study. Read More

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Characteristics, Comorbidities, Complications, and Outcomes Among 802 Patients With Severe Acute Respiratory Syndrome Coronavirus 2 in a Community Hospital in Florida.

Crit Care Explor 2021 May 12;3(5):e0416. Epub 2021 May 12.

Division of Academic Affairs and Research, Orlando Regional Healthcare, Orlando, FL.

Objectives: Coronavirus disease 2019 continues to increase throughout the United States. Despite the rapid progression of the disease, there is limited information of the factors associated with mortality in Florida. This study aims to review the demographics, characteristics, comorbidities, complications, and outcomes of hospitalized patients, and their association with mortality. Read More

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Timing of Intubation in Coronavirus Disease 2019: A Study of Ventilator Mechanics, Imaging, Findings, and Outcomes.

Crit Care Explor 2021 May 12;3(5):e0415. Epub 2021 May 12.

Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL.

Objectives: Determine the variation in outcomes and respiratory mechanics between the subjects who are intubated earlier versus later in their coronavirus disease 2019 course.

Design: Retrospective cohort study.

Setting: Northwestern Memorial Hospital ICUs. Read More

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Prediction of Acute Respiratory Failure Requiring Advanced Respiratory Support in Advance of Interventions and Treatment: A Multivariable Prediction Model From Electronic Medical Record Data.

Crit Care Explor 2021 May 12;3(5):e0402. Epub 2021 May 12.

Department of Biomedical Informatics, Emory University, Atlanta, GA.

Background: Acute respiratory failure occurs frequently in hospitalized patients and often begins outside the ICU, associated with increased length of stay, cost, and mortality. Delays in decompensation recognition are associated with worse outcomes.

Objectives: The objective of this study is to predict acute respiratory failure requiring any advanced respiratory support (including noninvasive ventilation). Read More

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Pulmonary Barotrauma in COVID-19 Patients: Invasive versus Noninvasive Positive Pressure Ventilation.

Int J Gen Med 2021 24;14:2017-2032. Epub 2021 May 24.

Department of General Surgery and Urology, Faculty of Medicine, Jordan University of Science and Technology, King Abdullah University Hospital, Irbid, 22110, Jordan.

Purpose: This study aims to determine the incidence and outcome of COVID-19 patients who required positive pressure ventilation (PPV) and subsequently developed pulmonary barotrauma (PBT). Also, to investigate the risk factors and predictors of these complications to better understand the disease pathogenesis.

Patients And Methods: This retrospective analysis enrolled all adult COVID-19 patients admitted through the period from October 1, 2020, to December 31, 2020. Read More

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The effect of high flow nasal oxygen therapy in intensive care units: A systematic review and meta-analysis.

Expert Rev Respir Med 2021 Jun 3. Epub 2021 Jun 3.

Zhujiang Hospital, Guangzhou, 510280 China.

Background: High flow nasal oxygen (HFNO) therapy has been widely used in intensive care units (ICU); however, its efficacy remains inconclusive. This systematic review and meta-analysis aimed to compare the efficacy of HFNO therapy with that of alternative noninvasive oxygen therapies such as conventional oxygen therapy (COT) and noninvasive ventilation (NIV) in ICU.

Methods: A Pubmed, Embase, Web of Science, Cochrane Library database search, which identified studies that assessed the outcomes of HFNO in adult ICU patients, was performed in March 2020. Read More

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Central apnea and periodic breathing in children with underlying conditions.

J Sleep Res 2021 Jun 2:e13388. Epub 2021 Jun 2.

Assistance Publique-Hôpitaux de Paris (AP-HP), Pediatric Noninvasive Ventilation and Sleep Unit, Hôpital Necker-Enfants Malades, Paris, France.

Central sleep apneas and periodic breathing are poorly described in childhood. The aim of the study was to describe the prevalence and characteristics of central sleep apnea and periodic breathing in children with associated medical conditions, and the therapeutic management. We retrospectively reviewed all poly(somno)graphies with a central apnea index ≥ 5 events per hr in children aged > 1 month performed in a paediatric sleep laboratory over a 6-year period. Read More

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Noninvasive Respiratory Support in Neonates: A Review of Current Evidence and Practices.

Indian J Pediatr 2021 Jun 1. Epub 2021 Jun 1.

Department of Neonatology, Newborn Unit, Paramita Children's Hospital, Kothapet, L B Nagar, Hyderabad, Telangana, 500074, India.

Respiratory distress is a common problem seen in neonates, both preterm and full term. Appropriate use of respiratory support can be life-saving in these neonates. While invasive ventilation is unavoidable in some situations, noninvasive ventilation may be sufficient in several neonates. Read More

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Agreement Between Transcutaneous Monitoring and Arterial Blood Gases During COPD Exacerbation.

Respir Care 2021 Jun 1. Epub 2021 Jun 1.

Department of Anaesthesia and Intensive Care, Bispebjerg and Frederiksberg Hospital, University of Copenhagen, Copenhagen, Denmark.

Background: Transcutaneous measurements of CO and O (P , P ) are noninvasive and allow for continuous monitoring in adults with exacerbation of COPD, but substantial accuracy issues may exist. We investigated agreement between results of arterial blood gas analysis and transcutaneous measurements of CO and O in patients with COPD.

Methods: Adult subjects were monitored after acute admission to a respiratory intermediate care unit or ICU due to exacerbation of COPD and with ongoing noninvasive ventilation or immediately following extubation. Read More

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Effects of early extubation followed by noninvasive ventilation versus standard extubation on the duration of invasive mechanical ventilation in hypoxemic non-hypercapnic patients: a systematic review and individual patient data meta-analysis of randomized controlled trials.

Crit Care 2021 06 1;25(1):189. Epub 2021 Jun 1.

Department of Medicine - DIMED, Section of Anesthesiology and Intensive Care, University of Padua, Padua, Italy.

Background: Usefulness of noninvasive ventilation (NIV) in weaning patients with non-hypercapnic hypoxemic acute respiratory failure (hARF) is unclear. The study aims to assess in patients with non-hypercapnic hARF, the efficacy of NIV after early extubation, compared to standard weaning.

Methods: In this individual patient data meta-analysis, we searched EMBASE, Medline and Cochrane Central Register of Controlled Trials to identify potentially eligible randomized controlled trials published from database inception to October 2020. Read More

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Application of surgical mask with high-flow nasal cannula (HFNC) leads to improved oxygenation in patients with COVID-19: a set of case reports.

Vnitr Lek 2021 ;67(E-2):29-33

The new coronavirus SARS-CoV-2 is responsible for the development of acute infectious illness named COVID-19. While most people have a mild course of the disease, a significant minority of patients will develop some degree of respiratory insufficiency requiring hospitalization. In case of failure of conventional oxygen therapy, the method of choice in patients with respiratory insufficiency is ventilation with high-flow nasal cannula (HFNC). Read More

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Pheochromocytoma Multisystem Crisis: A Case Study.

Crit Care Nurse 2021 Jun;41(3):25-32

Josh Eckroth is a bedside and charge nurse in the mixed ICU, Asante Rogue Regional Medical Center.

Introduction: Known as the "great mimic," pheochromocytoma is rare and difficult to diagnose. When a pheochromocytoma begins to cause end-organ damage, it becomes pheochromocytoma multisystem crisis, an even more rare and deadly diagnosis.

Clinical Findings: N. Read More

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