19,956 results match your criteria Nicotine Addiction


Circulating ghrelin changes as a biomarker of the stress response and craving in abstinent smokers.

Pharmacol Biochem Behav 2022 Jun 21:173423. Epub 2022 Jun 21.

University of Minnesota School of Medicine, 1035 University Drive, Duluth, MN 55812-2487, USA. Electronic address:

Rationale: There has been growing interest in the role of ghrelin in stress and addiction. Ghrelin regulates central reward mechanisms by mediating the mesolimbic dopaminergic system. Stress also induces neurophysiological activations related to drug reward. Read More

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Clinical Condition of the Oral Cavity in the Adult Polish Population below 70 Years of Age after Myocardial Infarction-A Case-Control Study.

Int J Environ Res Public Health 2022 Jun 14;19(12). Epub 2022 Jun 14.

Department of Periodontal and Oral Mucosa Diseases, Medical University of Warsaw, 02-097 Warsaw, Poland.

According to recent scientific consensus, there is an increasing amount of evidence on the correlation between oral health and cardiovascular disease morbidity. The aim of the present study was to investigate the number of missing teeth, the presence of residual roots with necrotic pulp and teeth with caries, the type of teeth deficiencies, and periodontal status in patients after myocardial infarction (MI). A total of 151 patients after MI and 160 randomly selected controls without history of MI were enrolled in the study. Read More

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Episodic Future Thinking about Smoking-Related Illness: A Preliminary Investigation of Effects on Delay Discounting, Cigarette Craving, and Cigarette Demand.

Int J Environ Res Public Health 2022 Jun 10;19(12). Epub 2022 Jun 10.

Fralin Biomedical Research Institute, 1 Riverside Circle, Roanoke, VA 24016, USA.

Cigarette smokers show excessive delay discounting (devaluation of delayed rewards), which may contribute to tobacco use disorder. Episodic future thinking (EFT), or mental simulation of future events, has been shown to reduce both delay discounting and laboratory smoking behavior. Traditionally, EFT involves vividly imagining positive future events. Read More

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Bidirectionality of Smoking and Depression in Adolescents: a Systemic Review.

Trends Psychiatry Psychother 2022 Jun 23. Epub 2022 Jun 23.

Menninger Department of Psychiatry and Behavioral sciences, Baylor College of Medicine, Houston, TX, USA.

Objective: Recently, there is an increase in evidence that both smoking and mental health are continuously increasing among adolescents. This systematic review elucidates the research on evidence of the direction of association and risk factors influencing this relationship between smoking and depression. We also highlight the recent studies on the effects of electronic cigarettes and the development of the association between depression and smoking. Read More

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"Genetic influences impacting nicotine use and abuse during adolescence: insights from human and rodent studies".

Brain Res Bull 2022 Jun 20. Epub 2022 Jun 20.

Department of Biobehavioral Heatlh, Pennsylvania State University, University Park, PA. Electronic address:

Nicotine use continues to be a major public health concern, with an alarming recent rise in electronic cigarette consumption. Heritability estimates of nicotine use and abuse range from 40-80%, providing strong evidence that genetic factors impact nicotine addiction-relevant phenotypes. Although nicotine use during adolescence is a key factor in the development of addiction, it remains unclear how genetic factors impact adolescent nicotine use and abuse. Read More

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Contingency management for smokers with mental health disorders and smoking-sensitive conditions caused or exacerbated by tobacco use: A review of existing studies, intervention parameters, and research priorities.

Exp Clin Psychopharmacol 2022 Jun 23. Epub 2022 Jun 23.

Department of Psychology.

Cigarette smoking is highly prevalent in people with smoking-sensitive conditions and mental health disorders. As early as the 1960s, evidence indicated the efficacy of contingency management (CM) for smoking cessation in various populations. This invited review is a critical appraisal of existing CM studies on smoking cessation in populations presenting smoking-sensitive conditions. Read More

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Identifying Hotspots of People Diagnosed of Tuberculosis with Addiction to Alcohol, Tobacco, and Other Drugs through a Geospatial Intelligence Application in Communities from Southern Brazil.

Trop Med Infect Dis 2022 May 24;7(6). Epub 2022 May 24.

Department of Maternal-Infant and Public Health Nursing, Ribeirão Preto College of Nursing, University of São Paulo, Ribeirão Preto 05403-000, Sao Paulo, Brazil.

(1) Background: tuberculosis (TB) is considered one of the leading causes of death worldwide by a single infectious agent. This study aimed to identify hotspots of people diagnosed with tuberculosis and abusive use of alcohol, tobacco, and other drugs in communities through a geospatial intelligence application; (2) Methods: an ecological study with a spatio-temporal approach. We considered tuberculosis cases diagnosed and registered in the Notifiable Diseases Information System, which presented information on alcoholism, smoking, and drug abuse. Read More

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Associations between classic psychedelics and nicotine dependence in a nationally representative sample.

Sci Rep 2022 Jun 22;12(1):10578. Epub 2022 Jun 22.

Department of Psychology, Harvard University, 33 Kirkland St, Cambridge, MA, 02138, USA.

Tobacco use is the single largest cause of preventable death worldwide, but none of the established treatments aimed at smoking cessation work for a majority of smokers. As such, there is an urgent need for interventions capable of reliably treating nicotine addiction. The use of classic psychedelics has been associated with lower odds of many forms of substance dependence. Read More

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TOBACCO USE DISORDER AND DUAL DISORDERS Joint statement by the Spanish Psychiatry Society and the Spanish Dual Disorders Society.

Actas Esp Psiquiatr 2022 Jun 1;50(Supplement):77-138. Epub 2022 Jun 1.

Catedrática de Psiquiatría. Universidad de Oviedo, Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto Universitario de Neurociencias del Principado de Asturias (INEUROPA), Instituto de Investigación sanitaria del Principado de Asturias (ISPA), Servicio de Salud del Principado de Asturias (SESPA). Asturias, España. Miembro de la Sociedad Española de Psiquiatría (SEP).

Tobacco Use Disorder (TUD) is a health problem of the first order in the world population, affecting a vulnerable population, such as people with other mental disorders, whose morbidity and mortality are increased as a result. Read More

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A Community-Based Exploratory Cross-Sectional Study of Elder Abuse Perpetration or Victimization Among Elders in Ethiopia, 2022.

Clin Interv Aging 2022 15;17:957-969. Epub 2022 Jun 15.

Department of Nursing, Mizan-Tepi University, Mizan Aman, South West Regional State, Ethiopia.

Background: Elderly abuse and comorbid problematic substance use, disability, and physical and mental illness have been major problems in low-income countries. In most countries, the elderly are the most neglected segment of the population, and there is insufficient information about elderly abuse perpetration or victimization in low-income countries like Ethiopia. Therefore, this study was aimed to assess elderly abuse perpetration or victimization among the elderly in Mizan Aman town, southwest Ethiopia. Read More

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Po and Pb content in the smoke of Heated Tobacco Products versus Conventional Cigarette smoking.

Sci Rep 2022 Jun 20;12(1):10314. Epub 2022 Jun 20.

Institute of Radiation Physics, Lausanne University Hospital and University of Lausanne, Grand Pré 1, 1007, Lausanne, Switzerland.

Po is a radioactive component of conventional cigarette tobacco smoke and is a recognized carcinogen. Despite the expanding market of heated tobacco products, no data are available on the activity of Po in the smoke of IQOS Heets cigarette. We determined the Po activity in the mainstream smoke of thirteen cigarette brands available on the Swiss market using a smoking machine and compared the results to the Po activity measured in the mainstream smoke of the IQOS system. Read More

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Arrêt du tabac : une personnalisation nécessaire des programmes de sevrage.

Sante Publique 2021 ;33(4):505-515

Objective: With 13 million smokers in France in 2019, smoking remains a major health issue. The LAST (Lieux d'accompagnement à la santé sans tabac [Locations for Health Support without Tobacco]) project set up in New-Aquitaine aims to encourage smokers to get help to quit smoking.

Method: In order to identify the barriers and levers to be mobilized to encourage smokers to seek help and then build with them the ideal cessation program, an individual qualitative study based on semi-structured interviews was conducted in May 2019 with 19 smokers at the contemplation or preparation step (transtheo-retical model). Read More

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Nicotine replacement gums dependence: A case report of a new potential addiction.

Encephale 2022 Jun 17. Epub 2022 Jun 17.

North Western Mental Health, Melbourne, Australia.

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The effect of aerobic exercises of different intensities on anxiety, cigarette addiction, sleep quality, and quality of life in former smokers.

Ir J Med Sci 2022 Jun 20. Epub 2022 Jun 20.

Physiotherapy and Rehabilitation, Health Science Faculty, Hasan Kalyoncu University, Havalimanı yolu üzeri 8.km, Gaziantep, 27010, Turkey.

Background: There is a worldwide struggle to quit smoking and prevent relapsing. Aerobic exercises are frequently utilized to aid in smoking cessation and prevent relapse.

Aims: This study aimed to investigate the effects of aerobic exercises of different intensity on the level of anxiety, smoking addiction, and quality of sleep and life in former smokers. Read More

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Tobacco Treatment Outcomes for Hospital Patients With and Without Mental Health Diagnoses.

Front Psychiatry 2022 26;13:853001. Epub 2022 May 26.

Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC, United States.

Background: The prevalence of mental health conditions is higher in cigarette smokers than nonsmokers. However, those with diagnosed mental health disorders are understudied within general inpatient hospital settings. This study seeks to evaluate how having a mental health diagnosis influences response to a brief opt-out inpatient tobacco treatment intervention. Read More

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Éducation thérapeutique chez les patients coronariens : impact sur le sevrage tabagique.

Ann Cardiol Angeiol (Paris) 2022 Jun 16. Epub 2022 Jun 16.

Service de Prévention et de Sécurité des Soins, CHU Sahloul, Sousse, Tunisie; Faculté de Médecine de Sousse, Université de Sousse, Sousse, Tunisie. Electronic address:

Aim Of The Study: To describe the results of a therapeutic education program (cessation rate and success factors) among smoking coronary patients followed in the smoking cessation clinic at Sahloul University Hospital in Sousse during the period from 2015 to 2020.

Patients And Methods: A descriptive cross-sectional study was conducted among smokers with coronary artery disease who presented to the smoking cessation clinic at Sahloul University Hospital during the period from 2015 to 2020. The data collection was done by reviewing the records of smokers. Read More

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Effectiveness of brief counselling in a hospital setting for smoking cessation and risky alcohol drinking reduction: randomised clinical trial protocol.

Rev Colomb Psiquiatr (Engl Ed) 2022 Jun 15. Epub 2022 Jun 15.

Departamento de Medicina Preventiva y Social, Hospital Universitario de San Ignacio, Bogotá, Colombia. Electronic address:

Introduction: Chronic diseases are a public health problem, and 80% of them are related to modifiable risk factors such as unhealthy diet, physical inactivity, smoking, and risky alcohol consumption. Although the intervention in smoking and hazardous alcohol drinking has proven to be effective in Primary Care, it is unknown whether it works in the same way in the hospital setting.

Objective: To evaluate the effectiveness of brief counselling in order to modify the stage of change in smokers and at-risk drinkers treated in a high complexity hospital. Read More

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Change in distress about police brutality and substance use among young people, 2017-2020.

Drug Alcohol Depend 2022 Jun 10;237:109530. Epub 2022 Jun 10.

Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90089, USA; Institute for Addiction Science, University of Southern California, Los Angeles, CA 90089, USA.

Background: It is unknown whether increasing attention to police brutality is a source of stress associated with substance use risk among young people.

Methods: A longitudinal racially/ethnically diverse cohort from Los Angeles, California (n = 1797) completed baseline (2017; mean age: 17.9) and follow-up (2020; mean age: 21. Read More

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Changes in tobacco use in the early phase of COVID-19 pandemic in Hong Kong: a qualitative study.

Nicotine Tob Res 2022 Jun 18. Epub 2022 Jun 18.

School of Public Health, The University of Hong Kong, Hong Kong SAR, China.

Introduction: Changes in tobacco use and related personal and environmental factors amid the COVID-19 pandemic can be captured by qualitative studies, but they are few in non-Western populations. We assessed the perceived links between tobacco use and COVID-19, and changes in the use of cigarettes, electronic cigarettes (ECs) and heated tobacco products (HTPs) in the early phase of the pandemic in Hong Kong, where lockdown was not implemented.

Methods: Semi-structured telephone interviews were conducted from January to June 2021 in 95 participants (36 EC users, 28 HTP users, 32 exclusive cigarette users). Read More

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Cigarette Smoke Extract, but Not Electronic Cigarette Aerosol Extract, Inhibits Monoamine Oxidase and Produces Greater Acute Aversive/Anhedonic Effects Than Nicotine Alone on Intracranial Self-Stimulation in Rats.

Front Neurosci 2022 25;16:868088. Epub 2022 May 25.

Hennepin Healthcare Research Institute, Minneapolis, MN, United States.

Conventional tobacco cigarettes appear to have greater abuse liability than non-combusted products such as electronic cigarettes (ECs) and nicotine replacement therapy (NRT). This may be due to the higher levels of behaviorally active non-nicotine constituents [e.g. Read More

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Therapeutic Potential of Histamine H3 Receptors in Substance Use Disorders.

Curr Top Behav Neurosci 2022 Jun 16. Epub 2022 Jun 16.

Department of Pharmacology and Toxicology, Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

Substance use disorders are a leading cause of morbidity and mortality, and available pharmacological treatments are of modest efficacy. Histamine is a biogenic amine with four types of receptors. The histamine H receptor (HR) is an autoreceptor and also an heteroreceptor. Read More

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Classic Psychedelics in Addiction Treatment: The Case for Psilocybin in Tobacco Smoking Cessation.

Curr Top Behav Neurosci 2022 Jun 16. Epub 2022 Jun 16.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

This manuscript reviews research suggesting that classic psychedelics (5-HT2A receptor agonists) are effective in treating addictions including tobacco use disorder. I review historical research from the 1950s to 1970s suggesting that classic psychedelics are associated with addiction recovery across pharmacologically distinct drugs of addiction. I then review anthropological reports about ceremonial use of classic psychedelics and epidemiological studies that are consistent with anti-addiction efficacy. Read More

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The effect of the COVID-19 lockdown on mental health care use in South Africa: an interrupted time-series analysis.

Epidemiol Psychiatr Sci 2022 Jun 15;31:e43. Epub 2022 Jun 15.

Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.

Aims: The coronavirus disease 2019 (COVID-19) pandemic and ensuing restrictions have negatively affected the mental health and well-being of the general population, and there is increasing evidence suggesting that lockdowns have led to a disruption of health services. In March 2020, South Africa introduced a lockdown in response to the COVID-19 pandemic, entailing the suspension of all non-essential activities and a complete ban of tobacco and alcohol sales. We studied the effect of the lockdown on mental health care utilisation rates in private-sector care in South Africa. Read More

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Understanding the implementation strategy of a secondary care tobacco addiction treatment pathway (the CURE project) in England: a strategic behavioural analysis.

BMJ Open 2022 Jun 14;12(6):e054739. Epub 2022 Jun 14.

Department of Social Work, Education and Community Wellbeing, Northumbria University, Newcastle upon Tyne, Tyne and Wear, UK.

Objectives: The Conversation, Understand, Replace, Experts and evidence-based treatment (CURE) project implemented an evidence-based intervention that offers a combination of pharmacotherapy and behavioural support to tobacco-dependent inpatients. Understanding key characteristics of CURE's implementation strategy, and identifying areas for improvement, is important to support the roll-out of nationwide tobacco dependence services. This study aimed to (1) specify key characteristics of CURE's exiting implementation strategy and (2) develop theoretical-informed and stakeholder-informed recommendations to optimise wider roll-out. Read More

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Investigating the reciprocal temporal relationships between tobacco consumption and psychological disorders for youth: an international review.

BMJ Open 2022 Jun 13;12(6):e055499. Epub 2022 Jun 13.

College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia

Objective: To investigate reciprocal temporal relationships between tobacco consumption and psychological disorders for youth. Review DATA SOURCES: Five databases (PubMed, Embase, Scopus, CINAHL and PsycINFO) on 26 September 2019 and updated on 11 May 2021, indexing tobacco, mental illness and longitudinal. Methods used consensus and multiple reviewers. Read More

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Acute glucagon-like peptide-1 receptor agonist liraglutide prevents cue-, stress-, and drug-induced heroin-seeking in rats.

Behav Pharmacol 2022 Jun 7. Epub 2022 Jun 7.

Department of Neural and Behavioral Sciences, Penn State College of Medicine.

Substance use disorder is challenging to treat due to its relapsing nature. In the last decade, opioid use disorder has been a threat to public health, being declared an epidemic by the Centers for Disease Control and Prevention. This is a tragic situation, considering there currently are only three effective, yet not ideal, treatments to prevent relapse to opioids. Read More

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Prevalence and Associated Factors of Attention-Deficit Hyperactivity Disorder among Children Aged 6-17 Years in North Eastern Ethiopia.

Ethiop J Health Sci 2022 Mar;32(2):321-330

Department of Psychiatry, College of Health Science, Debre Berhan University, Debre Berhan, Ethiopia.

Background: Attention-deficit hyperactivity disorder is one of the public neurodevelopmental disorders characterized by impulsivity and restlessness or hyperactivity. This study aimed to assess the prevalence of Attention-deficit hyperactivity disorder and its associated factors among children aged 6 to 17 years in Shewa Robit town, Northeastern Ethiopia, 2020.

Methods: A community-based cross-sectional study was conducted among 365 children aged 6-17 years from Feb 1-March 30, 2020, at Shewa Robit town. Read More

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The multitarget FAAH inhibitor/D3 partial agonist ARN15381 decreases nicotine self-administration in male rats.

Eur J Pharmacol 2022 Jun 8;928:175088. Epub 2022 Jun 8.

School of Pharmacy, Pharmacology Unit, University of Camerino, Italy. Electronic address:

Tobacco use disorder is a worldwide health problem for which available medications show limited efficacy. Nicotine is the psychoactive component of tobacco responsible for its addictive liability. Similar to other addictive drugs, nicotine enhances mesolimbic dopamine transmission. Read More

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Efficiency of Inhaled Cannabidiol in Cannabis Use Disorder: The Pilot Study Cannavap.

Front Psychiatry 2022 24;13:899221. Epub 2022 May 24.

Addiction Department of René Muret Hospital, Assistance Publique des Hopitaux de Paris, Sevran, France.

Introduction: Cannabidiol (CBD), the second most prevalent cannabinoid found in cannabis, is considered to be safe for use. Studies suggest that CBD may be of benefit in treating cannabis use disorder (CUD). In clinical practice, CBD is already being used by patients who are trying to reduce or stop their cannabis consumption. Read More

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Exercise and Reduced Nicotine Content Cigarettes in Adult Female Smokers: A Pilot Trial.

Int J Environ Res Public Health 2022 May 29;19(11). Epub 2022 May 29.

Department of Kinesiology, University of Virginia, Charlottesville, VA 22904, USA.

Although Reduced Nicotine Cigarettes (RNC) are suggested to improve smoking cessation and cardiometabolic health in relation to cancer risk, the effectiveness of exercise training with RNC on smoking cessation and cardiometabolic health is unknown. Female smokers (N = 27) were randomized to: (1) usual nicotine cigarettes (i.e. Read More

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