289 results match your criteria Nevus Sebaceus


BRAF and KRAS mutations in tubular apocrine adenoma and papillary eccrine adenoma of the skin.

Hum Pathol 2018 Mar 12;73:59-65. Epub 2017 Dec 12.

Department of Pathology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei 10051, Taiwan.

Tubular apocrine adenoma (TAA) and papillary eccrine adenoma (PEA) are benign sweat gland tumors. Their names imply that they exhibit apocrine and eccrine differentiation, respectively. However, morphologically they are very similar and are often indistinguishable. Read More

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March 2018
5 Reads

Detection of somatic mutations in secondary tumors associated with nevus sebaceus by targeted next generation sequencing. Comment on Kitamura et al.

Int J Dermatol 2018 Jan 31;57(1):120-122. Epub 2017 Oct 31.

Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL, USA.

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January 2018

Epidermal nevus syndromes: New insights into whorls and swirls.

Pediatr Dermatol 2018 Jan 16;35(1):21-29. Epub 2017 Oct 16.

Department of Dermatology, University of California, San Francisco, Santa Rosa, CA, USA.

Knowledge of the molecular underpinnings of many epidermal nevi and epidermal nevus syndrome has expanded rapidly in recent years. In this review and update on epidermal nevus syndrome, we will cover recent genetic discoveries involving epidermal nevi, including nevus sebaceus, keratinocytic epidermal nevus, nevus comedonicus, congenital hemidysplasia with ichthyosiform nevus and limb defects syndrome, phakomatosis pigmentokeratotica, Becker's nevus, porokeratotic adnexal ostial nevus, inflammatory linear verrucous epidermal nevi, and cutaneous-skeletal hypophosphatemia syndrome. We will discuss how newly defined mutations relate to the biology reflected in the cutaneous patterns seen in these mosaic disorders and how new molecular data has informed our understanding of these diseases and shaped management decisions. Read More

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January 2018
5 Reads

Simultaneous Development of Three Different Neoplasms of Trichilemmoma, Desmoplastic Trichilemmoma and Basal Cell Carcinoma Arising from Nevus Sebaceus.

Arch Craniofac Surg 2017 Mar 25;18(1):46-49. Epub 2017 Mar 25.

Department of Pathology, Busan-Baik Hospital, Inje University School of Medicine, Busan, Korea.

Nevus sebaceus is a hamartoma of the sebaceous gland that occurs congenitally, from which various secondary tumors can arise with a prevalence of 5%-6%. Benign neoplasms commonly arise from nevus sebaceous, but they have a very low malignant potential. Two neoplasms may occasionally arise within the same lesion, but it is rare for three or more neoplasms to occur in a nevus sebaceus simultaneously. Read More

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March 2017
5 Reads

Pigmented Trichoblastoma of Nose: An Unusual Occurrence.

J Clin Diagn Res 2017 Jul 1;11(7):MD09-MD10. Epub 2017 Jul 1.

Junior Resident, Department of Ear, Nose and Throat, Sri Siddhartha Medical College, Agalakote, Karnataka, India.

Nevus sebaceus of Jadassohn is a congenital tumour affecting the scalp and face. It is usually presented as a pigmented patch or plaque. It is a complex cutaneous hamartoma which involves pilosebaceous follicle, epidermis and adnexal structures. Read More

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July 2017
4 Reads

CD13 is a marker for onychofibroblasts within nail matrix onychodermis: Comparison of its expression patterns in the nail unit and in the hair follicle.

J Cutan Pathol 2017 Nov 18;44(11):909-914. Epub 2017 Aug 18.

Dermpath Diagnostics, Port Chester, New York.

Background: We previously demonstrated the presence of onychodermis, a specialized mesenchymal cell population beneath the nail matrix and proximal nail bed demonstrating CD10 expression. We hypothesize that the onychodermis could be the nail analog of the follicular dermal papilla, which is known to express CD13. We compare CD13 expression patterns between specialized mesenchymes of nail and hair, and compare these findings with CD10 expression patterns. Read More

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November 2017
14 Reads

Dermoscopy of syringocystadenoma papilliferum.

Australas J Dermatol 2018 Feb 11;59(1):e59-e61. Epub 2017 Jul 11.

Dermatology and Skin Cancer Unit, Arcispedale S. Maria Nuova, Institute for Research and Health Care, Reggio Emilia, Italy.

Syringocystadenoma papilliferum is a benign adnexal neoplasm frequently seen in association with other adnexal tumours. We report the dermoscopic features of three cases of syringocystadenoma papilliferum developing in naevus sebaceus. Clinically the lesions were characterised by exophytic papillary structures. Read More

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February 2018
2 Reads

Dermoscopic Analysis of Nevus Sebaceus of Jadassohn: A Study of 13 Cases.

Skin Appendage Disord 2017 May 16;3(2):83-91. Epub 2017 Mar 16.

Department of Dermatology, University Hospital Hassan II, Fez, Morocco.

Background: Nevus sebaceus of Jadassohn (NSJ) is a complex cutaneous hamartoma with various clinical appearances.

Aim: To describe different dermoscopic patterns of this nevus according to its evolutionary stages.

Methods: This was an analytical study of NSJ carried out in the Department of Dermatology at the University Hospital Hassan II, Fez, Morocco. Read More

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May 2017
2 Reads

Patient Perspectives: What is a nevus sebaceus?

Authors:

Pediatr Dermatol 2017 May;34(3):359-360

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May 2017
2 Reads

A Case of Syringocystadenoma Papilliferum with Tubular Papillary Adenoma of the Chest.

J Nippon Med Sch 2017 ;84(2):79-82

Department of Dermatology, Nippon Medical School.

We report a case of syringocystadenoma papilliferum (SCAP) combined with tubular papillary adenoma (TPA) arising on the chest of a 45-year-old Japanese woman. Histopathological examination revealed the characteristic findings of SCAP in the superficial part of the lesion and those of TPA in the deeper part. We reviewed the English literature about this combination. Read More

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September 2017
4 Reads

Sebaceous Neoplasms.

Authors:
Katharina Flux

Surg Pathol Clin 2017 Jun;10(2):367-382

Department of Dermatology, University of Heidelberg, Im Neuenheimer Feld 440, 69120 Heidelberg, Germany; Labor für Dermatohistologie und Oralpathologie, Bayerstrasse 69, 80335 München, Munich, Germany. Electronic address:

Sebaceous skin tumors are classified into sebaceous adenoma, sebaceoma, and sebaceous carcinoma. An additional group of cystic sebaceous tumors indicate the Muir-Torre syndrome (MTS). Cystic sebaceous tumors are considered as morphologic variants of the 3 main categories. Read More

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June 2017
3 Reads

Giant proliferating trichilemmal cyst arising from a nevus sebaceus growing for 30 years.

J Cutan Pathol 2017 Apr 17. Epub 2017 Apr 17.

Department of Pathology, Dermatopathology Division, Sylvester Comprehensive Cancer Center and Miller School of Medicine, University of Miami, Miami, Florida.

Nevus sebaceus of Jadassohn, a congenital cutaneous hamartoma, has the potential to develop into various epidermal adnexal-origin neoplasms. While the most common neoplasms are trichoblastoma or syringocystadenoma, proliferating trichilemmal cysts are exceptionally rare. We report a case of a 63-year-old Cuban male with a giant proliferating trichilemmal cyst arising from a nevus sebaceus on the right shoulder which had been growing for 30 years. Read More

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April 2017
3 Reads

Sebaceous Carcinoma Arising Within a Nevus Sebaceus Excised by Mohs Micrographic Surgery.

Dermatol Surg 2017 09;43(9):1181-1184

Department of Dermatology, Houston Methodist Hospital, Houston, Texas The Surgery Center at Plano Dermatology, Plano, Texas Department of Dermatology, Kelsey-Seybold Clinic, Houston, Texas Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, Texas.

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September 2017
1 Read

Professional interest in dermatopathology of Stanisław Ostrowski - the only one State Polish President among physicians.

Pol J Pathol 2017;68(4):277-283

President of prewar Lvov and Polish Republic on Exile, associate professor Stanisław Ostrowski was a dermatologist with a keen interest in dermatopathology. This study was based on original resources, which - mainly reports of his own authorship - were focused on dermatopathology. Stanisław Ostrowski provided excellent description of naevus epitheliomatosus sebaceus Wolters-Friboes both in Polish and German to be cited after decades in renowned handbooks of dermatopahtology published by Springer Verlag. Read More

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June 2018
3 Reads

Linear trichilemmomas on the ankle of a 28-year-old female.

J Cutan Pathol 2017 Jan 21;44(1):93-97. Epub 2016 Oct 21.

Department of Dermatology, Tufts Medical Center, Boston, MA, USA.

Trichilemmomas are benign cutaneous proliferations derived from the outer root sheath of the hair follicle. They most often occur on the head and neck region and show a female predominance. When multiple, they are associated with Cowden syndrome (CS), a rare disorder due to an autosomal dominant germline mutation in PTEN (phosphatase and tensin homolog on chromosome 10), a tumor suppressor gene. Read More

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January 2017
19 Reads

Reply to "Apocrine intraductal carcinoma in situ in nevus sebaceus: two case reports".

J Cutan Pathol 2016 11 1;43(11):1079-1080. Epub 2016 Sep 1.

Dermatopathology Friedrichshafen, Friedrichshafen, Germany.

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November 2016
2 Reads

Syringocystadenocarcinoma Papilliferum In Situ, a Variant of Cutaneous Adenocarcinoma In Situ: A Case Report With Literature Review.

Am J Dermatopathol 2016 Oct;38(10):762-5

*Department of Dermatology, The Third Xiangya Hospital of Central South University, Changsha, China; †Department of Surgery, and ‡Department of Pathology and Laboratory Medicine and Department of Dermatology, Hofstra Northwell School of Medicine, NY.

Syringocystadenocarcinoma papilliferum in situ, a variant of cutaneous adenocarcinoma in situ, is extremely rare. Only 9 cases have been published to date with 2 cases demonstrating pagetoid epidermal involvement. In this study, we report a case of syringocystadenocarcinoma papilliferum in situ with pagetoid epidermal involvement arising from a long-standing nevus sebaceus on the scalp of a 60-year-old woman. Read More

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October 2016
11 Reads

Coexistent trichilemmoma and trichoblastoma without associated nevus sebaceus.

J Biol Regul Homeost Agents 2016 Apr-Jun;30(2 Suppl 2):17-20

Department of Medical 1Department of Pathology, Division of Dermatopathology, University of Virginia Health System, Charlottesville, Virginia.

Trichilemmoma and trichoblastoma are benign adnexal neoplasms derived from the hair follicle unit. While trichilemmomas are closely associated with the epidermis, trichoblastomas are found within the dermis and subcutaneous tissue. Both tumors have been reported to arise within nevus sebaceus of Jadassohn (NSJ). Read More

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July 2016
3 Reads

Basal Cell Carcinoma or Trichoblastoma? Dermoscopic Examination of Black Macules Developing in the Same Nevus Sebaceus.

Case Rep Oncol 2016 Jan-Apr;9(1):143-7. Epub 2016 Feb 20.

Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

Nevus sebaceus (NS) is a common congenital birthmark, and various tumors have been reported to develop in NS. Basal cell carcinoma (BCC) seldom occurs in NS, and it is very important to be able to clinicopathologically distinguish BCC from trichoblastoma. Herein, we describe a case of BCC and trichoblastoma occurring simultaneously in the same NS, including the differential dermoscopic features. Read More

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June 2016
4 Reads

Case of squamous cell carcinoma arising within a linear nevus sebaceus on the trunk.

J Dermatol 2016 Oct;43(10):1236-1237

Department of Dermatology, Saitama Medical University Saitama Medical Center, Saitama, Japan.

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October 2016
2 Reads

Linear syringocystadenoma papilliferum on the retroauricular area associated with nevus sebaceus.

Dermatol Online J 2016 Nov 15;22(11). Epub 2016 Nov 15.

Specialist of Dermatology and Venereology, Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey.

Syringocystadenoma papilliferum is a rare cutaneous adnexal tumor that usually arises in the head and neck region. It may develop de novo or within a nevus sebaceus. Linear syringocystadenoma papilliferum is an uncommon variant of this benign tumor. Read More

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November 2016
1 Read

Basal Cell Carcinoma and Syringocystadenoma Papilliferum Arising in Nevus Sebaceous on Face-A Rare Entity.

Indian J Dermatol 2015 Nov-Dec;60(6):637

Department of Pathology, Hind Institute of Medical Sciences, Safedabad, Barabanki, Uttar Pradesh, India.

Nevus sebaceus of Jadassohn is a congenital cutaneous hamartoma comprising of multiple skin structures. It has the potential to develop into variety of neoplasms of various epidermal adnexal origins. While multiple tumors may occasionally arise, it is unusual to develop two different types of tumor, benign and malignant, to arise simultaneously within a single sebaceus nevus. Read More

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December 2015
1 Read

Epidermal nevus syndromes.

Handb Clin Neurol 2015 ;132:291-316

Departments of Dermatology and Community and Family Medicine, University of California San Francisco, Santa Rosa, CA, USA. Electronic address:

The term epidermal nevus syndrome (ENS) has been used to describe the association of epidermal hamartomas and extracutaneous abnormalities. Although many continue to use the term "ENS," it is now understood that this is not one disease, but rather a heterogeneous group with distinct genetic profiles defined by a common cutaneous phenotype: the presence of epidermal and adnexal hamartomas that are associated with other organ system involvement. One commonality is that epidermal nevi often follow the lines of Blaschko and it appears the more widespread the cutaneous manifestations, the greater the risk for extracutaneous manifestations. Read More

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August 2016
5 Reads

Nevus sebaceus with basal cell carcinoma, poroma, and verruca vulgaris.

Indian J Pathol Microbiol 2015 Oct-Dec;58(4):534-6

Department of Pathology, Gülhane Military Medical Academy, Ankara, Turkey.

Nevus sebaceus (NS) is a congenital, benign, hamartomatous lesion and it is possible to see several benign or malignant tumors accompanying it. One of these is the poroma, which is very rare, and has only been reported twice before, in the English literature. In this paper, we presented two new cases of NS. Read More

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April 2017
2 Reads

Systematised naevus sebaceus resulting from post-zygotic mutation in HRAS.

Australas J Dermatol 2017 Feb 23;58(1):58-60. Epub 2015 Sep 23.

St John's Institute of Dermatology, King's College London, Guy's Hospital, London, UK.

Naevus sebaceus has recently been shown to result from post-zygotic mutations in HRAS, KRAS or occasionally NRAS. We present details of a neonate with extensive naevus sebaceus in whom we identified a pathogenic mutation in HRAS (c.37G > C; p. Read More

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February 2017
21 Reads

Endocrine mucin-producing sweat gland carcinoma arising in nevus sebaceous.

J Cutan Pathol 2015 Sep 22. Epub 2015 Sep 22.

Department of Cellular Pathology, Hospital El Bierzo, Ponferrada, Spain.

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September 2015
1 Read

Nevus sebaceus: a clinicopathological study of 168 cases and review of the literature.

Int J Dermatol 2016 Feb 17;55(2):193-200. Epub 2015 Sep 17.

Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.

Background: Nevus sebaceus is a hamartoma composed of abnormal epidermal and dermal components with clinical and histopathological features that change with aging. Prophylactic excision of the lesion was advised historically considering its potential for giving rise to malignant tumors. However, whether early prophylactic excision should be performed has been questioned recently as most of the tumors have been found to be benign in origin. Read More

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February 2016
4 Reads

Secondary neoplasms arising from nevus sebaceus: A retrospective study of 450 cases in Taiwan.

J Dermatol 2016 Feb 12;43(2):175-80. Epub 2015 Sep 12.

Department of Dermatology, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan.

Nevus sebaceus is frequently associated with the development of secondary neoplasms. Incidences of malignant transformation vary among different reports and few data is available regarding Asian populations. We aimed to determine the characteristics of secondary tumors developing from nevus sebaceus in a Taiwanese population and to review the published work. Read More

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February 2016
7 Reads

A Histological Snapshot of Hypothetical Multistep Progression From Nevus Sebaceus to Invasive Syringocystadenocarcinoma Papilliferum.

Am J Dermatopathol 2016 Jan;38(1):56-62

Departments of *Pathology, and †Dermatology, University of Alabama at Birmingham, Birmingham, AL.

Syringocystadenocarcinoma papilliferum (SCACP) is an extremely rare adnexal neoplasm, believed to arise in a preexisting nevus sebaceus of Jadassohn (NSJ) through a multistep progression process. This hypothetical process involves an NSJ giving rise to syringocystadenoma papilliferum, which then presumably undergoes malignant transformation in rare circumstances to give rise to SCACP in situ, which finally progresses to an invasive SCACP. Of the 30 SCACP cases reported so far, none have documented the process from a birthmark to the final invasive lesion, with histological evidence of each step, in a single tumor. Read More

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January 2016
2 Reads

Ceruminous adenoma (ceruminoma) arising in a nevus sebaceus of Jadassohn within the external auditory canal of a 3 year-old boy - A case report.

Int J Pediatr Otorhinolaryngol 2015 Nov 20;79(11):1932-4. Epub 2015 Jul 20.

Medical University of Warsaw, Department of Pediatric Otolaryngology, Poland.

Nevus sebaceus of Jadassohn is a congenital yellowish hairless skin lesion, mainly located on the head and neck. A common phenomenon is the coexistence of secondary tumors within the lesion. These are mainly benign tumors, the majority of which are trichoblastoma and syringocystadenoma papilliferum. Read More

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November 2015
4 Reads

Nevus Sebaceus of Jadassohn.

Eplasty 2015 20;15:ic38. Epub 2015 Jul 20.

Division of Plastic Surgery, Department of Surgery, Morsani College of Medicine, University of South Florida, Tampa.

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August 2015
3 Reads

Syringocystadenoma papilliferum arising on naevus sebaceus: A 6-year-old child case described with dermoscopic features.

Australas J Dermatol 2015 May;56(2):e53-4

Department of Dermatology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.

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May 2015
3 Reads

Sebaceus and Becker's Nevus: Overview of Their Presentation, Pathogenesis, Associations, and Treatment.

Am J Clin Dermatol 2015 Jun;16(3):197-204

Albert Einstein College of Medicine, Bronx, NY, USA.

Nevus sebaceus (NS) and Becker's nevus (BN) are two variants of epidermal nevi. NS clinically presents as a yellowish-orange, hairless plaque on the scalp, face, or neck, while BN presents as a tan-to-brown hyperpigmented, sometimes hypertrichotic, plaque typically on the chest and shoulder. Histologically, NS displays mature or nearly mature sebaceus glands as well as acanthosis and fibroplasia of the papillary dermis. Read More

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June 2015
3 Reads

Trichoblastoma, syringocystadenoma papilliferum, desmoplastic trichilemmoma and tumor of the follicular infundibulum with signet-ring cells, all arising in nevus sebaceus.

J Cutan Pathol 2015 Sep 12;42(9):645-51. Epub 2015 May 12.

Department of Dermatology, University of Iowa, Iowa City, IA, USA.

Herein, we describe a 63-year-old male with multiple tumors arising within a nevus sebaceus on the posterior scalp. On histopathologic examination, four distinct tumors were identified: trichoblastoma, syringocystadenoma papilliferum, desmoplastic trichilemmoma and tumor of the follicular infundibulum (TFI). Within the TFI component of the nevus sebaceus, there was intracytoplasmic accumulation of eosinophilic keratin, as shown on pancytokeratin-stained sections, imparting a signet-ring appearance to the cells. Read More

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September 2015
5 Reads

Identification of somatic KRAS mutation in a Korean baby with nevus sebaceus syndrome.

Ann Lab Med 2015 Jan 8;35(1):178-80. Epub 2014 Dec 8.

Department of Pediatrics, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.

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January 2015
1 Read

Apocrine intraductal carcinoma in situ in nevus sebaceus: two case reports.

J Cutan Pathol 2014 Dec 11;41(12):944-9. Epub 2014 Nov 11.

Department of Dermatology, Hospital Infanta Cristina, Madrid, Spain.

Ductal carcinoma in situ (DCIS) in the mammary glands consists of a proliferation of ductal luminal cells with preserved polarity but lacking the marked intercellular cohesion of hyperplastic cells. We report two cases of DCIS arising in the apocrine glandular structures of a nevus sebaceus (NS). The first patient was a 44-year-old woman with a ductal neoplasm composed of multilayered ductal elements with a monomorphous cellularity and a polar orientation of nuclei. Read More

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December 2014
3 Reads

[Developmental abnormalities and nevi of the scalp].

Authors:
V Behle H Hamm

Hautarzt 2014 Dec;65(12):1022-9

Klinik und Poliklinik für Dermatologie, Venerologie und Allergologie, Universitätsklinikum Würzburg, Josef-Schneider-Straße 2, 97080, Würzburg, Deutschland.

Unusual congenital or early-onset skin lesions on the scalp often pose a diagnostic challenge particularly as the clinical evaluation may be hampered by dense hair growth. Thus, this paper provides a concise review on developmental abnormalities and nevi with exclusive or predominant scalp localization. Aplasia cutis congenita occurs as an isolated finding, in association with genetic syndromes, nevi and anomalies or as a consequence of intrauterine trauma and teratogens. Read More

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December 2014
2 Reads

Two Concurrent Facial Epidermal Nevi without Systemic Abnormalities: Nevus Sebaceus and Nevus Comedonicus.

Ann Dermatol 2014 Aug 31;26(4):501-4. Epub 2014 Jul 31.

Department of Dermatology, Kyungpook National University School of Medicine, Daegu, Korea.

Epidermal nevi (EN) are hamartomatous lesions derived from epidermal components originating from pluripotent cell mutations. They have been categorized according to their predominant component. The existence of >2 types of EN concurrently within a single area or within contiguous areas has been rarely reported. Read More

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August 2014
7 Reads

Rapidly growing pigmented tumor on a scalp nevus sebaceous of a pediatric patient: Observation or excision.

Dermatol Online J 2014 Jul 15;20(7). Epub 2014 Jul 15.

School of Medicine Temple University.

A 14-year-old girl presented with a new, rapidly growing, pigmented tumor on a previously existing yellowish, verrucous plaque on the scalp. The patient received complete surgical excision. Routine histology ruled out basal cell carcinoma (BCC) and the histological diagnosis was pigmented trichoblastoma arising in nevus sebaceous (NS). Read More

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July 2014
5 Reads

Photoletter to the editor: A neurocutaneous rarity: phacomatosis pigmentokeratotica.

J Dermatol Case Rep 2014 Jun 30;8(2):58-9. Epub 2014 Jun 30.

Department of Dermatology, Freiburg University Medical Center, Freiburg, Germany.

Phacomatosis pigmentokeratotica is characterized by the coexistence of nevus sebaceus, papular nevus spilus and associated neurologic abnormalities. We report a case of phacomatosis pigmentokeratotica in a 28-year-old male who presented with palmar-plantar dysesthesia and ipsilateral brain hemiatrophy. As a characteristic neuroimaging finding of the disorder, we found multiple hypointense lesions involving the ipsilateral hemisphere. Read More

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June 2014
1 Read

Update on pediatric dermatologic surgery from tots to teens.

Authors:
Julianne A Mann

Curr Opin Pediatr 2014 Aug;26(4):452-9

Department of Dermatology and Pediatrics, Oregon Health and Science University, Portland, Oregon, USA.

Purpose Of Review: Children and their parents typically present to pediatricians to discuss treatment options for melanocytic nevi, nevus sebaceus, port-wine stains, and hemangiomas. Each of these conditions may be medically managed, but in some situations surgical intervention may be preferable.

Recent Findings: Although recent studies have improved our understanding of melanoma risk among patients with congenital nevi, prospective trials are needed to more accurately assess whether surgical excision mitigates this risk. Read More

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August 2014
1 Read

Frequent activating HRAS mutations in trichilemmoma.

Br J Dermatol 2014 Nov 30;171(5):1073-7. Epub 2014 Sep 30.

Department of Pathology, National Taiwan University Hospital, Taipei, Taiwan; Graduate Institute of Pathology, College of Medicine, National Taiwan University, Taipei, Taiwan.

Background: Trichilemmoma is a benign follicular epithelial tumour exhibiting outer root sheath differentiation. It is associated with Cowden syndrome and naevus sebaceus (NS), but the pathogenesis of sporadic tumours is poorly understood. Recently, NS was found to be caused by postzygotic HRAS or KRAS mutations. Read More

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November 2014
4 Reads

Syringocystadenocarcinoma papilliferum with locoregional metastases.

Dermatol Online J 2014 Apr 16;20(4):22335. Epub 2014 Apr 16.

United States Navy.

Syringocystadenocarcinoma papilliferum (SCACP) is a rare malignant counterpart of syringocystadenoma papilliferum (SCAP). To date, less than 30 cases have been reported, and of those, only three had locoregional metastases [1,2]. Herein, we report a case of a 42-year-old man with a rapidly growing nodule on his right parietal scalp ultimately diagnosed as SCACP arising in association with a preexisting SCAP and nevus sebaceus. Read More

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April 2014
5 Reads

Desmoplastic sebaceoma arising from nevus sebaceus: a new variant.

J Cutan Pathol 2014 Jun 2;41(6):509-12. Epub 2014 Apr 2.

Department of Pathology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Tao-Yuan, Taiwan.

Nevus sebaceus is known to have the potential to develop into various secondary tumors. We observed a sebaceoma arising from a nevus sebaceus excised from the left cheek of a 51-year-old woman. This sebaceoma showed desmoplastic change similar to that observed in desmoplastic trichoepithelioma and desmoplastic trichilemmoma. Read More

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June 2014
4 Reads

Acantholytic squamous cell carcinoma arising in a nevus sebaceous: A case report.

Authors:
Ahmed Alhumidi

Int J Health Sci (Qassim) 2013 Nov;7(3):343-6

Assistant Professor and Consultant of Histopathology and Dermatopathology, King Khalid University hospital, King Saud University, P.O. Box 2925, Riyadh - 11461, Department of Pathology (32), Riyadh, Kingdom of Saudi Arabia.

Although nevus sebaceous (NS) is known to develop various types of secondary neoplasms, it rarely causes carcinoma and only fifteen cases of secondary squamous cell carcinoma (SCC) have been reported. We report a rare variant of SCC (acantholytic type) arising in nevus sebaceus. Read More

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November 2013
1 Read

Development of six tumors in a sebaceus nevus of jadassohn: report of a case.

Korean J Pathol 2013 Dec 24;47(6):569-74. Epub 2013 Dec 24.

Department of Family Medicine, Diskapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey. ; Department of Family Medicine, University of Antwerp, Antwerp, Belgium.

Nevus sebaceus of Jadassohn is a congenital cutaneous hamartoma comprised of multiple skin structures. It has the potential to develop into variety of neoplasms of various epidermal adnexal origins. While multiple tumors may occasionally arise, it is unusual for more than four tumors to arise simultaneously within a single sebaceus nevus. Read More

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December 2013
2 Reads

Syringocystadenoma.

Dermatol Online J 2013 Dec 16;19(12):20722. Epub 2013 Dec 16.

New York University School of Medicine.

We present a case of a 35-year-old woman with a yellow, verrucous, and itchy plaque on her scalp. Within this plaque, there was an erythematous, bleeding papule. Histopathologic findings were compatible with a diagnosis of syringocystadenoma papilliferum within a nevus sebaceous. Read More

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December 2013
1 Read

Naevus sebaceus: a mosaic RASopathy.

Clin Exp Dermatol 2014 Jan;39(1):1-6

Dermatology Centre, Salford Royal NHS Foundation Trust, Stott Lane, University of Manchester, Manchester, UK.

Epidermal naevi are common cutaneous mosaic disorders that occur in 0.1-0.3% of live births. Read More

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January 2014
6 Reads

Neoplastic skin lesions of the scalp in children: a retrospective study of 265 cases in Taiwan.

Eur J Dermatol 2014 Jan-Feb;24(1):70-5

Department of Dermatology and Allergy, Technische Universität München, Biedersteiner Strasse 29, 80802 Munich, Germany.

Background: The preferential occurrence of certain skin neoplasms on the scalp of children raises concerns from their parents and warrants special diagnostic and therapeutic approaches.

Objective: To explore the demographic and clinical characteristics of scalp neoplasms in the pediatric population, with attention to malignant tumors and systemic syndromes.

Methods: Scalp neoplasms in patients aged 12 years or younger were retrospectively collected in 1990-2010 from two tertiary referral centers in Taiwan. Read More

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February 2015
2 Reads