CD13 is a marker for onychofibroblasts within nail matrix onychodermis: comparison of its expression patterns in the nail unit and in the hair follicle.
- Ji-Hye Park,
- Dong-Youn Lee,
- Kee-Taek Jang,
- Sang-Yun Ha,
- Ghee Young Kwon,
- Kyung-Hoon Lee,
- Jong Sup Shim,
- Eun Ji Kwon
J Cutan Pathol 2017 Jul 14. Epub 2017 Jul 14.
Department of Dermpath Diagnostics, New York, Port Chester, NY, USA.
Background: We previously demonstrated the presence of onychodermis, a specialized mesenchymal cell population beneath the the nail matrix and proximal nail bed demonstrating CD10 expression. We hypothesize that the onychodermis could be the nail analog of the follicular dermal papilla, which is known to express CD13. We compare CD13 expression patterns between specialized mesenchymes of nail and hair, and compare these findings with CD10 expression patterns. Read More