326 results match your criteria Nevus Sebaceus


Secondary Malignant Tumors Arising in Nevus Sebaceus: Two Case Reports.

Diagnostics (Basel) 2022 Jun 13;12(6). Epub 2022 Jun 13.

Department of Dermatology, International University of Health and Welfare, Narita 286-8520, Chiba, Japan.

Nevus sebaceus is a benign tumor that is present at birth and is often seen on the scalp or face. Secondary malignant tumors sometimes occur in nevus sebaceus in adulthood. Herein, we present two malignant tumors arose from nevus sebaceus. Read More

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Multiple secondary neoplasms in nevus sebaceus excision.

Proc (Bayl Univ Med Cent) 2022 3;35(2):241-242. Epub 2021 Nov 3.

Dermatology, Intermountain Hospital, Logan, Utah.

Nevus sebaceus is a congenital hamartoma associated with several secondary tumors. We report the case of a 19-year-old woman who presented with changes in a nevus sebaceus lesion on her parietal scalp, which was subsequently excised. Upon pathological examination, both basaloid hamartoma and syringocystadenoma papilliferum were noted within the specimen, which is rare. Read More

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November 2021

A case of naevus sebaceus of Jadassohn of the scalp in Jamaica.

J Surg Case Rep 2021 Dec 28;2021(12):rjab552. Epub 2021 Dec 28.

Department of Pathology, Cornwall Regional Hospital, Montego Bay, Jamaica.

Naevus sebaceus (NS), also referred to as NS of Jadassohn, is a rare non-melanocytic congenital cutaneous hamartoma with mainly sebaceous differentiation. NS has pluripotent potential with the possible evolution of benign and/or malignant neoplastic transformation. Literature of clinical audit and retrospective analyses conclude that there is no need for prophylactic excision except for cases in which malignant transformation is suspected. Read More

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December 2021

Cerebriform congenital scalp mass.

JAAD Case Rep 2021 Oct 23;16:105-107. Epub 2021 Aug 23.

Department of Dermatology, University of Florida College of Medicine, Gainesville, Florida.

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October 2021

Topical sirolimus therapy for nevus sebaceus and epidermal nevus: A case series.

J Am Acad Dermatol 2021 Aug 21. Epub 2021 Aug 21.

Departments of Dermatology and Pediatrics, Yale University School of Medicine, New Haven, Connecticut. Electronic address:

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Somatic KRAS mutation affecting codon 146 in linear sebaceous nevus syndrome.

Am J Med Genet A 2021 12 13;185(12):3825-3830. Epub 2021 Jul 13.

UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.

Linear Sebaceous Nevus Syndrome is a rare disorder that presents with nevus sebaceus in association with corneal dermoids, colobomas, choroidal osteomas, and arachnoid cysts. It is thought to represent a mosaic RASopathy. These are disorders characterized by postzygotic somatic mutation in genes involved in RAS/MAPK signaling pathway. Read More

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December 2021

Trichoblastoma Arising From the Nevus Sebaceus of Jadassohn.

Cureus 2021 May 29;13(5):e15325. Epub 2021 May 29.

Dermatology Unit, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences, Casablanca, MAR.

Trichoblastoma is a rare benign skin adnexal tumour, belonging to the category of trichogenic tumours. The clinical and histological findings may often be confused with basal cell carcinoma, a malignant epidermal skin tumour. We report here a case of a 70-year-old man presented with a dome-shaped, dark-pigmented nodule within a yellowish hairless plaque on the scalp. Read More

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Syringocystadenoma papilliferum of the scalp.

Dermatol Online J 2021 Mar 15;27(3). Epub 2021 Mar 15.

Department of Dermatology, University of Illinois College of Medicine, Peoria, IL.

Syringocystadenoma papilliferum is a rare, benign adnexal tumor of eccrine or apocrine origin that typically presents at birth or before puberty. Syringocystadenoma papilliferum is associated with a nevus sebaceus in about 40% of cases. We present a 50-year old woman with a pink-orange plaque and nodule on the scalp, consistent with syringocystadenoma papilliferum that arose within a nevus sebaceus. Read More

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Peculiar non-syndromic midline variant of nevus sebaceus on the chest of an elderly male.

J Cutan Pathol 2021 Jul 29;48(7):1000-1002. Epub 2021 Apr 29.

Department of Dermatology, University of Heidelberg, Heidelberg, Germany.

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A Rare Case of Porocarcinoma and Trichoblastoma Arising in a Nevus Sebaceus of Jadassohn.

Case Rep Dermatol Med 2021 3;2021:7598086. Epub 2021 Mar 3.

Department of Dermatology, University of Rochester Medical Center, 40 Celebration Drive, Rochester, NY 14642, USA.

Nevus sebaceus of Jadassohn, or "organoid nevus," is a common, benign hamartoma of the skin consisting of epithelial and adnexal components. Its natural history and association with neoplastic growths is well documented. The majority of concomitant neoplasms are benign-trichoblastoma and syringocystadenoma papilliferum are most frequently discovered-but malignant tumors have been described. Read More

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Nevus sebaceus of Jadassohn - high frequency ultrasound imaging and videodermoscopy examination. Case presentation.

Med Pharm Rep 2021 Jan 29;94(1):112-117. Epub 2021 Jan 29.

Dermatology Department, Rostov State Medical University, Russia.

Nevus sebaceus of Jadassohn (NSJ) is a congenital cutaneous hamartoma mainly developing from pilosebaceous unit cells. NSJ has the potential to develop into a variety of benign and malignant tumors, which are not limited to sebaceous differentiation. The dynamical monitoring for the earliest malignant transformation is necessary. Read More

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January 2021

Phacomatosis spilosebacea: A new name for a distinctive binary genodermatosis.

J Am Acad Dermatol 2021 Feb 11. Epub 2021 Feb 11.

Department of Dermatology, Medical Center-University of Freiburg, Freiburg, Germany.

Phacomatosis pigmentokeratotica (PPK) is defined by the association of papular nevus spilus arranged in a flag-like pattern and sebaceous nevus following Blaschko's lines. A systematic search of the worldwide literature retrieved 95 well-established PPK cases. An additional 30 cases were excluded for a number of reasons. Read More

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February 2021

An updated review of the sebaceous gland and its role in health and diseases Part 2: Pathophysiological clinical disorders of sebaceous glands.

Dermatol Ther 2021 03 19;34(2):e14862. Epub 2021 Feb 19.

Veterans Affairs Hospital and SUNY Downstate Dermatology Service, Brooklyn, New York, USA.

Sebaceous glands are sebum-secreting components of pilosebaceous units. In the second of this two-part series, we review the pathologies in which sebaceous glands are primarily and secondarily implicated. They are primarily involved in steatocystoma simplex and multiplex, sebaceous gland hyperplasia, sebaceoma, sebaceous adenoma, sebaceous carcinoma, nevus sebaceus, and folliculosebaceous cystic hamartoma. Read More

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Dermoscopy of collision tumor arising in nevus sebaceus of Jadassohn.

JAAD Case Rep 2021 Feb 17;8:74-76. Epub 2020 Dec 17.

Department of Dermatology, Mohammed V University in Rabat, Ibn Sina University Hospital, Rabat, Morocco.

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February 2021

An updated review of the sebaceous gland and its role in health and diseases Part 1: Embryology, evolution, structure, and function of sebaceous glands.

Dermatol Ther 2021 01 1;34(1):e14695. Epub 2021 Jan 1.

Veterans Affairs Hospital and SUNY Downstate Dermatology Service, Brooklyn, New York, USA.

Sebaceous glands are sebum-secreting components of pilosebaceous units. The embryological development of the sebaceous gland follows that of the hair follicle and epidermal tissue, beginning between weeks 13 and 16 of fetal development. New sebaceous glands do not normally develop following birth, but their size increases with age. Read More

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January 2021

Intraepidermal apocrine differentiation in an infantile nevus sebaceus.

J Cutan Pathol 2021 Apr 6;48(4):595-597. Epub 2020 Nov 6.

Division of Dermatology, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.

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A practical review of dermoscopy for pediatric dermatology part II: Vascular tumors, infections, and inflammatory dermatoses.

Pediatr Dermatol 2020 Sep 4;37(5):798-803. Epub 2020 Aug 4.

Department of Dermatology, Tufts Medical Center, Boston, Massachusetts, USA.

In addition to the evaluation of melanocytic growths (Part I), dermoscopy is helpful in the identification and management of vascular tumors, skin infections, and inflammatory conditions. In this practical review, we present the classic dermoscopic findings of the following: vascular tumors, infectious conditions (molluscum contagiosum, scabies, verruca vulgaris), inflammatory conditions (psoriasis, atopic dermatitis), juvenile xanthogranuloma, and nevus sebaceus. Read More

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September 2020

Case of melorheostosis associated with ipsilateral verrucous epidermal nevus, linear connective tissue nevus, diffuse hyperpigmentation and hypertrichosis: A fortuitous coincidence?

J Dermatol 2020 Sep 12;47(9):1063-1066. Epub 2020 Jul 12.

Department of Experimental, Diagnostic and Specialty Medicine - Division of Dermatology, University of Bologna, Bologna, Italy.

Melorheostosis (MEL) is a rare benign bone disorder that can be associated with several anomalies, including vascular abnormalities, nevus sebaceus, unilateral nevoid telangiectasia, linear scleroderma and hypertrichosis. We report the case of a 6-year-old patient who showed an unusual co-occurrence of bone hyperostosis and different skin lesions affecting the same side of the body: MEL, verrucous epidermal nevus, connective tissue nevus, linear scleroderma-like disorder, hyperpigmentation and hypertrichosis. The spatial co-occurrence of these conditions made us speculate as to whether they originated from a common genetic mechanism or if their co-occurrence was completely accidental. Read More

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September 2020

Nevus sebaceus with syringocystadenoma papilliferum, prurigo nodularis, apocrine cystadenoma, basaloid follicular proliferation, and sebaceoma: case report and review of nevus sebaceus-associated conditions.

Dermatol Online J 2020 Feb 15;26(2). Epub 2020 Feb 15.

School of Medicine, University of California San Diego, La Jolla, CA.

Nevus sebaceus is a benign skin hamartoma of congenital onset that grows during puberty, and in adulthood can develop secondary benign and malignant neoplasms. The most common benign neoplasms occurring in nevus sebaceus are believed to be syringocystadenoma papilliferum, trichilemmoma, and trichoblastoma. A patient with nevus sebaceus developed not only syringocystadenoma papilliferum but also prurigo nodularis within her hamartomatous lesion; multiple biopsies were necessary to establish the diagnoses. Read More

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February 2020

Basaloid tumors arising from seborrheic keratosis: Malignant basal cell carcinoma or benign basaloid follicular hamartomatous proliferation?

J Cutan Pathol 2020 Mar 3;47(3):207-218. Epub 2019 Dec 3.

Department of Medicine, Mackay Medical College, New Taipei City, Taiwan.

Background: Basaloid tumors arising from seborrheic keratosis (SK) that resembled basal cell carcinoma (BCC) were infrequently observed in our patients. They also exhibited morphologic features similar to those of trichoblastoma or basaloid follicular hamartoma.

Methods: We retrospectively collected cases of SK with basaloid tumors from 2001 to 2017. Read More

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Osteoma Cutis Associated with Nevus Sebaceus: Case Report and Review of Cutaneous Osteoma-associated Skin Tumors (COASTs).

Cureus 2019 Jun 20;11(6):e4959. Epub 2019 Jun 20.

Dermatology, San Diego Family Dermatology, National City, USA.

Osteoma cutis is a benign cutaneous lesion characterized by the presence of bone within the dermis or subcutaneous fat. It most often develops in association with other skin lesions such as cutaneous tumors. Nevus sebaceus is a benign hamartoma of the skin that is composed of epidermal and dermal components. Read More

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Mites within Nevus Sebaceus Lesion of an Immune-Competent 7-Month-Old Infant.

Ann Dermatol 2019 Aug 1;31(Suppl):S34-S35. Epub 2019 Jul 1.

Department of Dermatology, SMG-SNU Boramae Medical Center, Seoul, Korea.

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Squamous cell carcinoma with perineural involvement in nevus sebaceus.

Cutis 2019 Apr;103(4):E17-E19

Department of Pathology, Laboratory Services, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.

Nevus sebaceus (NS), also known as an organoid nevus, is a congenital skin hamartoma involving the pilosebaceous unit, epidermis, and adnexa, frequently occurring in the scalp area. During childhood, the lesion remains unchanged but may subsequently increase in size during puberty in response to hormonal release, with possible tumor development. We report a case of squamous cell carcinoma (SCC) development in an NS with histologic evidence of perineural involvement on the anterior central scalp of a 13-year-old adolescent girl. Read More

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Syringocystadenoma papilliferum arising in a naevus sebaceous.

Malays J Pathol 2019 Apr;41(1):47-49

University of Malaya, Faculty of Medicine, Department of Medicine, Division of Dermatology, Kuala Lumpur, Malaysia.

Naevus sebaceus is a cutaneous hamartoma with the potential of developing into benign or malignant neoplasms. Syringocystadenoma papilliferum (SCAP) have been reported to originate from naevus sebaceus. SCAP is a rare, benign adnexal skin tumour of apocrine or eccrine type of differentiation which typically presents as a nodule or a plaque on the scalp or face. Read More

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Optimal Timing for Surgical Excision of Nevus Sebaceus on the Scalp: A Single-Center Experience.

Dermatol Surg 2020 01;46(1):20-25

Department of Dermatology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan.

Background: Treatment of nevus sebaceus (NS) on the scalp is usually surgical excision, but the optimal timing is debatable. The scalp presents significant challenges to the reconstructive surgeon because the lack of elasticity of the scalp makes the repair of defects difficult.

Objective: The aim of this study was to investigate the optimal timing for surgical excision of NS on the scalp through postoperative outcomes. Read More

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January 2020

Papular nevus spilus syndrome: old and new aspects of a mosaic RASopathy.

Eur J Dermatol 2019 Feb;29(1):2-5

Department of Dermatology, Medical Center-University of Freiburg, Hauptstr 7, 79104 Freiburg, Germany.

The co-existence of papular nevus spilus (PNS) and ipsilateral extracutaneous abnormalities involving peripheral nerves of the skin or muscles was originally described as "speckled lentiginous nevus syndrome". To avoid confusion with macular nevus spilus, the condition was recently re-named "papular nevus spilus syndrome". In addition to 14 published cases, we identified six new cases via a search of the worldwide literature. Read More

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February 2019

Nonablative Fractional 1,550-nm Laser for the Treatment of an Unusual Nevus Sebaceus.

Dermatol Surg 2019 12;45(12):1728-1731

Dermatology and Laser Surgery Center, Houston, Texas West Lake Dermatology, Austin, Texas Dermatology and Laser Surgery Center, Houston, Texas.

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December 2019

Hamartomas of skin and soft tissue.

Semin Diagn Pathol 2019 Jan 11;36(1):48-61. Epub 2018 Dec 11.

Department of Pathology and Cell Biology - USF Health, Ruffolo, Hooper, and Associates, Tampa, FL, United States. Electronic address:

Hamartomas are benign lesions composed of aberrant disorganized growth of mature tissues. Choristomas are similar, except that they are composed of tissues not normally found at the anatomic site in which the lesion is arising. A wide range of hamartomas and choristomas can arise in the skin and soft tissue. Read More

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January 2019

Cover Image: Naevus sebaceus affected by overgrowth of Malassezia globosa.

Br J Dermatol 2018 12;179(6):1432-1433

Department of Dermatovenereology, West China Hospital, West China Hospital of Stomatology, Sichuan University, Chengdu, 610041, China.

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December 2018

Primary cutaneous apocrine carcinoma arising within a nevus sebaceus.

Cutis 2018 Oct;102(4):291-294

Nova Southeastern University College of Osteopathic Medicine/Largo Medical Center, Florida, USA.

Nevus sebaceus (NS)(organoid nevus) is a benign follicular neoplasm that commonly occurs on the scalp, face, or neck. With time, it may give rise to benign or malignant tumors such as trichoblastoma, syringocystadenoma papilliferum, and basal cell carcinoma (BCC). Rarely, other types of neoplasms may develop. Read More

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October 2018