187 results match your criteria Nevus Comedonicus


Nevus Comedonicus with Epidermolytic Hyperkeratosis: A Case Report.

Iran J Pathol 2022 8;17(2):234-237. Epub 2022 Mar 8.

Department of Pathology, Imam Reza Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.

Nevus comedonicus (NC) is a rare developmental anomaly of the folliculosebaceous apparatus, which appears as numerous dilated papules containing firm, darkly pigmented, horny plugs. It appears shortly after birth and mostly before the age of 10; however, late-onset cases have been reported. There is no gender or racial predilection. Read More

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Linear Nevus Comedonicus.

J Cutan Med Surg 2022 Mar 23:12034754221088567. Epub 2022 Mar 23.

442339 Department of Dermatology and Venereology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India.

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Nevus Comedonicus Syndrome Associated with Psychiatric Disorder.

Diagnostics (Basel) 2022 Feb 2;12(2). Epub 2022 Feb 2.

Department of Pathology, Yonsei University College of Medicine, Seoul 03722, Korea.

Nevus comedonicus (NC) is a rare hamartoma of the pilosebaceous unit origin. The association with extracutaneous abnormalities defines NC syndrome (NCS). Fewer than 50 cases of NCS have been reported in the English literature. Read More

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February 2022

Nevus comedonicus: An image to remember.

J Paediatr Child Health 2022 Feb 9. Epub 2022 Feb 9.

Dermatology Department, Hospital Santa Maria, Centro Hospitalar Universitário de Lisboa Norte, Lisbon, Portugal.

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February 2022

[Syndroms associated with benign skin tumors].

Hautarzt 2022 Feb 25;73(2):114-126. Epub 2022 Jan 25.

Pädiatrische Dermatologie, Dermatoonkologisches Forschungungslabor, Colentina Klinik, Carol-Davila-Universität für Medizin und Pharmazie, Bukarest, Rumänien.

Benign skin tumors represent a wide category of diseases. The diagnosis is usually provided by the clinical aspect and the patient history. The pathological examination is not always considered necessary and in most cases the treatment is removal of the lesion by cryotherapy, electrosurgery or laser ablation. Read More

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February 2022

Acne Syndromes and Mosaicism.

Biomedicines 2021 Nov 21;9(11). Epub 2021 Nov 21.

Departments of Dermatology, Venereology, Allergology, and Immunology, Dessau Medical Center, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg, 06847 Dessau, Germany.

Abnormal mosaicism is the coexistence of cells with at least two genotypes, by the time of birth, in an individual derived from a single zygote, which leads to a disease phenotype. Somatic mosaicism can be further categorized into segmental mosaicism and nonsegmental somatic mosaicism. Acne is a chronic illness characterized by inflammatory changes around and in the pilosebaceous units, commonly due to hormone- and inflammatory signaling-mediated factors. Read More

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November 2021

Rolled Hairs in Two Cases of Naevus Comedonicus of the Scalp.

Acta Derm Venereol 2021 Sep 15;101(9):adv00549. Epub 2021 Sep 15.

Department of Dermatology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, 160-8582 Tokyo, Japan.

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September 2021

Extensive Nevus Comedonicus with Inflammatory Nodules and Cysts Controlled with Adalimumab.

Ann Dermatol 2021 Aug 1;33(4):361-364. Epub 2021 Jul 1.

Department of Dermatology, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.

Nevus comedonicus is a very rare skin disorder characterized by the presence of comedo-like dilated pores with keratinous plugs, rarely resulting in painful recurrent inflammatory nodules or cysts. It presents as localized or extensive form. It displays unilaterally or bilaterally segmental distribution. Read More

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Mosaic NEK9 mutation, fibrous dysplasia and premature puberty in naevus comedonicus syndrome.

Br J Dermatol 2021 12 7;185(6):1247-1249. Epub 2021 Sep 7.

Dermatologie, Centre de Référence des Maladies Rares de la Peau, Toulouse, France.

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December 2021

Giant nevus comedonicus of the entire lower left limb protecting from the associated bullous pemphigoid: A hypothetical role of NEK9 mutation?

J Dermatol 2021 Aug 17;48(8):1250-1252. Epub 2021 May 17.

Section of Dermatology, DiSSal, San Martino Polyclinic Hospital IRCCS, University of Genova, Genova, Italy.

We present the case of a 92-year-old woman, with bullous pemphigoid (BP) and a concomitant nevus comedonicus (NC) presenting as an asymptomatic, linear lesion of the entire lower left limb, formed by multiple comedones. Dermoscopy of the NC and histopathology confirmed the clinical and dermoscopic suspect of giant congenital nevus comedonicus. The two entities presented no overlap. Read More

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Three novel pathogenic NEK9 variants in patients with nevus comedonicus: A case series.

J Am Acad Dermatol 2022 04 2;86(4):958-960. Epub 2021 Apr 2.

Faculty of Medicine, Institute of Human Genetics, Medical Center - University of Freiburg, Freiburg, Germany. Electronic address:

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Nevus comedonicus syndrome: A systematic review of the literature.

Authors:
Daniele Torchia

Pediatr Dermatol 2021 Mar 22;38(2):359-363. Epub 2021 Jan 22.

Department of Dermatology, James Paget University Hospital, Great Yarmouth, UK.

Nevus comedonicus (NC) syndrome is a condition first identified in 1978. The cause of NC syndrome has been recently proven to be a gain-of-function, mosaic postzygotic mutation of the NEK9 gene. A systematic review of the literature retrieved 43 well-established cases of NC syndrome reported so far. Read More

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Dermoscopy of late-onset nevus comedonicus.

An Bras Dermatol 2020 Nov - Dec;95(6):773-775. Epub 2020 Sep 14.

Dermatology Unit, Galliera Hospital, Genova, Italy; Surgical Pathology, Galliera Hospital, Genova, Italy.

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Bilateral nevus comedonicus of the eyelids: An unusual cause of ptosis and ectropion.

Am J Ophthalmol Case Rep 2020 Dec 29;20:100907. Epub 2020 Aug 29.

Department of Ophthalmology, Ain Shams University, Cairo, Egypt.

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December 2020

Nevus Comedonicus Suppurativa: A Report of a Novel Entity.

J Clin Aesthet Dermatol 2020 Jun 1;13(6):36-39. Epub 2020 Jun 1.

Drs. Sharma, Sahu, Dayal, and Yadav are with the Department of Dermatology at the Pandit B.D. Sharma Postgraduate Institute of Medical Sciences in Rohtak, Haryana, India.

Nevus comedonicus and hidradenitis suppurativa (HS) are disorders of the pilosebaceous unit sharing a similar pathogenesis of follicular occlusion. To our knowledge, less than 10 cases of HS-like lesions complicating nevus comedonicus have been reported. We describe a six-year-old female child with congenital linear nevus comedonicus in the left axilla and groin, complicated by recurrent HS-like lesions in the two years prior to presenting to our clinic. Read More

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Punctate porokeratosis-pruritic and hyperkeratotic papules on the palms and feet.

Proc (Bayl Univ Med Cent) 2020 Jul 24;33(3):415-416. Epub 2020 Apr 24.

Division of Dermatology, Baylor University Medical CenterDallasTexas.

Porokeratosis is an uncommon cutaneous condition with multiple clinical variants that is defined by round patches with a raised, fine scaling border. Punctate porokeratosis is a rare variant of porokeratosis that is characterized by elevated, seed-like lesions of the palms and soles. While variants of porokeratosis may be associated with an increased risk of squamous cell carcinoma within the lesion, punctate porokeratosis does not increase the risk of squamous cell carcinoma. Read More

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Improvement of nevus comedonicus after repeated microneedling.

JAAD Case Rep 2020 Feb 30;6(2):152-153. Epub 2020 Jan 30.

Texas Tech University Health Sciences Center, Department of Dermatology, Lubbock, Texas.

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February 2020

Further delineation of the phenotypic spectrum of nevus comedonicus syndrome to include congenital pulmonary airway malformation of the lung and aneurysm.

Am J Med Genet A 2020 04 21;182(4):746-754. Epub 2020 Jan 21.

Division of Pediatrics, Section of Dermatology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.

Nevus comedonicus syndrome (NCS) is a rare epidermal nevus syndrome characterized by ocular, skeletal, and central nervous system anomalies. We present a 23-month-old boy with a history of a congenital pulmonary airway malformation (CPAM) of the lung and a congenital cataract who developed progressive linear and curvilinear plaques of dilated follicular openings with keratin plugs (comedones) on parts of his scalp, face, and body consistent with nevus comedonicus. MRI of the brain demonstrated an aneurysm of the right internal carotid artery. Read More

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Nevus Comedonicus With Acne Vulgaris and Obesity.

Dermatol Pract Concept 2020 31;10(1):e2020006. Epub 2019 Dec 31.

Dermatology Unit, Department of Clinical Medicine and Surgery, Federico II University of Naples, Italy.

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December 2019

Bilateral nevus comedonicus of the eyelids: An unusual cause of ptosis and ectropion.

Am J Ophthalmol Case Rep 2020 Mar 17;17:100579. Epub 2019 Dec 17.

Department of Ophthalmology, Centre Hospitalier Universitaire de Martinique, Martinique, French West Indies, France.

Purpose: Nevus comedonicus is a rare developmental abnormality of the infundibulum of the hair follicle.

Observation: We report here an unusual case of bilateral extensive nevus comedonicus of the eyelids complicated by bilateral ptosis and ectropion of the lower eyelids. Blepharoplasty was performed on both upper eyelids. Read More

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An unexpected coexistence of two epidermal naevi on the scalp: Naevus comedonicus and naevus sebaceous.

Australas J Dermatol 2020 Feb 19;61(1):e142-e143. Epub 2019 Aug 19.

Department of Pathology, Faculty of Medicine, Trakya University, Edirne, Turkey.

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February 2020

Successful treatment of late-onset nevus comedonicus with Er:YAG laser.

J Cosmet Dermatol 2020 Apr 22;19(4):863-865. Epub 2019 Jul 22.

Department of Pathology, Faculty of Medicine, Bahçeşehir University, Istanbul, Turkey.

Nevus comedonicus, a rare congenital hamartoma of the pilosebaceous unit, is characterized by keratotic plugging. It usually occurs after birth and during early childhood. It rarely appears in adulthood. Read More

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An Unusual Birthmark on the Scalp: A Quiz.

Acta Derm Venereol 2019 Jul;99(9):846-847

Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 100730 Beijing, China.

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Late onset nevus comedonicus of scalp: a rare site for an uncommon condition.

Dermatol Online J 2019 Mar 15;25(3). Epub 2019 Mar 15.

Department of Dermatology, Venereology and Leprosy, Dr. Ram Manohar Lohia Post Graduate Institute of Medical Education and Research, New Delhi.

Nevus comedonicus is an uncommon hamartoma of the pilosebaceous unit characterized by keratin filled pits simulating open comedones. It may present at birth but is more commonly seen during childhood or adolescence. The most commonly affected sites are the face, neck, trunk, and arms with a few reported cases on palms, genitalia, and scalp. Read More

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A Microneedling Fractional Radiofrequency Device for the Treatment of Nevus Comedonicus.

Dermatol Surg 2020 01;46(1):148-150

Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, Massachusetts.

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January 2020

Dermoscopy of nevus comedonicus.

North Clin Istanb 2019 28;6(4):401-402. Epub 2018 Nov 28.

Department of Dermatology, Istanbul Medeniyet University Goztepe Training and Research Hospital, Istanbul, Turkey.

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November 2018

Late-Onset Nevus Comedonicus With Follicular Epidermolytic Hyperkeratosis-Case Report and Review of the Literature.

Am J Dermatopathol 2019 Jun;41(6):453-455

Section of Dermatology, Department of Medical Science and Public Health, University of Cagliari, Cagliari, Italy.

Nevus comedonicus is a rare cutaneous follicular hamartoma, characterized by the clustering of papules with firm, blackened horny buffers. It is usually present at birth or during childhood, although few cases of late-onset disease have been described. We present a case of postmenopausal-onset nevus comedonicus in a 55-year-old white woman without relevant medical history. Read More

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Mutation and expression of ABCA12 in keratosis pilaris and nevus comedonicus.

Mol Med Rep 2018 Sep 31;18(3):3153-3158. Epub 2018 Jul 31.

Department of Dermatology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong 510515, P.R. China.

Keratosis pilaris (KP) and nevus comedonicus (NC) are congenital keratinized dermatoses; however, the exact etiology of these two diseases is unclear. The objective of the present study was to identify the disease‑causing genes and their association with functional alterations in the development of KP and NC. Peripheral blood samples of one KP family, two NC families and 100 unrelated healthy controls were collected. Read More

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September 2018