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    1985 results match your criteria Neutrophilic Eccrine Hidradenitis

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    A phenotype combining hidradenitis suppurativa with Dowling-Degos disease caused by a founder mutation in PSENEN.
    Br J Dermatol 2017 Sep 18. Epub 2017 Sep 18.
    Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
    Dowling-Degos disease, featuring reticulate pigmentation, and familial hidradenitis suppurativa share many clinical features including autosomal dominant inheritance, flexural location and follicular defects. The co-existence of the two disorders was recently found to result from mutations in PSENEN, encoding protein presenilin enhancer gamma-secretase subunit. Here we report 4 additional families of Jewish Ashkenazi origin who presented with clinical features characteristic of both disorders. Read More

    Uncovering burden disparity: A comparative analysis of the impact of moderate-to-severe psoriasis and hidradenitis suppurativa.
    J Am Acad Dermatol 2017 Sep 13. Epub 2017 Sep 13.
    Genesis Research, Hoboken, New Jersey. Electronic address:
    Background: Psoriasis and hidradenitis suppurativa (HS) exhibit distinct clinical features, but no studies have directly compared the health-related quality of life (HRQoL) in patients with moderate-to-severe manifestations of these conditions.

    Objective: To determine which disease is associated with more severe HRQoL impairment.

    Methods: Weighted averages of each of the following baseline HRQoL measures were determined and compared between HS and psoriasis populations from 5 clinical trials: Visual Analog Scale (VAS) for pain, Total Work Productivity Impairment, Dermatology Life Quality Index; EuroQOL 5D VAS, and Short Form-36 Health Survey. Read More

    Hidradenitis Suppurativa is Associated with Myocardial Infarction, but Not Stroke or Peripheral Arterial Disease of Lower Extremities.
    Br J Dermatol 2017 Sep 15. Epub 2017 Sep 15.
    Department of Dermatology, Roskilde Hospital, Køgevej 7-13, 4000, Roskilde.
    We performed a comparative cross-sectional study of the potential association of HS and the three outcome events: self-reported MI, self-reported stroke, and PAD measured by ankle-brachial index (ABI) ≤ 0.9. We included a self-reported HS group (n=430) identified in the general suburban population study (GESUS) using a validated questionnaire (2) (Table 1). Read More

    Resident Rounds Part III: Case Report: Metastatic Cutaneous Squamous Cell Carcinoma in an African American Female.
    J Drugs Dermatol 2017 Jan;16(1):81-84
    Cutaneous squamous cell carcinoma (cSCC) is the most common skin cancer diagnosed in African Americans.1 Twenty to forty percent of cSCCs reported in African Americans are related to chronic scarring processes or areas of in ammation.2 Risk factors for developing cSCCs in patients of color include chronic scars resulting from burns, skin ulcers, and radiation sites; and chronic inflammatory diseases such as discoid lupus and hidradenitis suppuritiva. Read More

    Review of Current Immunologic Therapies for Hidradenitis Suppurativa.
    Int J Rheumatol 2017 20;2017:8018192. Epub 2017 Aug 20.
    Division of Rheumatology and Immunology, Medical University of South Carolina, 96 Jonathan Lucas Street, Suite 822, Charleston, SC 29425, USA.
    Hidradenitis suppurativa (HS) is a chronic, recurrent, inflammatory disease of apocrine gland-bearing skin which affects approximately 1-4% of the population. The disease is more common in women and patients of African American descent and approximately one-third of patients report a family history. Obesity and smoking are known risk factors, but associations with other immune disorders, especially inflammatory bowel disease, are also recognized. Read More

    IBD LIVE Series-Case 8: Treatment Options for Refractory Esophageal Crohn's Disease and Hidradenitis Suppurativa.
    Inflamm Bowel Dis 2017 Oct;23(10):1667-1677
    1Assistant Professor of Medicine, Department of Medicine, Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia; 2Assistant Professor of Medicine, Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; 3Professor of Pathology, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia; 4Associate Director, Hershey Penn State IBD Center, Division of Gastroenterology and Hepatology, Department of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania; 5Chief, Division of Colon and Rectal Surgery, Milton S. Hershey Medical Center, Hershey, Pennsylvania; 6Director, Hershey Penn State IBD Center, Professor of Surgery, Peter and Marshia Carlino Chair in IBD, Penn State College of Medicine, Hershey, Pennsylvania; 7Associate Professor of Medicine and of The Dartmouth Institute for Health Policy and Clinical Practice, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire; 8Director of the Inflammatory Bowel Disease Center, the Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire; 9Assistant Professor of Medicine, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire; 10Staff Gastroenterologist, Inflammatory Bowel Disease Center, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire; 11Professor of Medicine, Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, North Carolina; 12Clinical Director and Director of the IBD Center, Section of Gastroenterology, Boston Medical Center, Boston, Massachusetts; 13Professor of Medicine, Boston University School of Medicine, Boston, Massachusetts; 14Professor of Medicine, Clinical and Translational Science, Co-Director of the IBD Center, Director of Translational IBD Research, Director, Nutrition Support Service, Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; 15Director, Division of Gastroenterology and Nutrition, Goryeb Children's Hospital, Atlantic Health, Morristown, New Jersey; 16Professor of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, New York; 17Interim Chief, Pediatric Gastroenterology, Hepatology, and Nutrition and Co-Director, Inflammatory Bowel Disease Center, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania; 18Professor of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; 19Professor of Medicine, Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, North Carolina; and 20Professor of Medicine, Associate Chief for Education, Co-Director, Inflammatory Bowel Disease Center, Head, IBD Clinical Program, Department of Medicine, Division of Gastroenterology, Hepatology and Nutrition, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

    Scrotal reconstruction and testicular prosthetics.
    Transl Androl Urol 2017 Aug;6(4):710-721
    Department of Urology, Einstein Healthcare Network/Fox Chase Cancer Center, Philadelphia, PA, USA.
    Scrotal surgery encompasses a wide-variety of surgical techniques for an even wider variety of indications. In this manuscript, we review our indications, techniques, and pit-falls for various reconstructive scrotal surgeries as-well-as surgical tips for placement of testicular prostheses. Penoscrotal webbing (PSW) is an abnormal, often-problematic distal insertion of scrotal skin onto the ventral penile shaft. Read More

    Proceeding report of the Symposium on Hidradenitis Suppurativa Advances (SHSA).
    Exp Dermatol 2017 Sep 12. Epub 2017 Sep 12.
    University of Toronto, Toronto, Canada.
    The Symposium on Hidradenitis Suppurativa Advances (SHSA) took place on 22-23 October 2016 at Women's College Hospital in Toronto, Canada. This symposium was a joint meeting of the Canadian Hidradenitis Suppurativa Foundation (CHSF), and the Hidradenitis Suppurativa Foundation (HSF Inc.) founded in USA. Read More

    Quality of Life Measurement in Acne. Position Paper of the European Academy of Dermatology and Venereology (EADV) Task Forces on Quality of Life and Patient Oriented Outcomes (QoL and PO) and Acne, Rosacea and Hidradenitis Suppurativa (ARHS).
    J Eur Acad Dermatol Venereol 2017 Sep 12. Epub 2017 Sep 12.
    Department of Dermatology and Wound Healing, Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff, UK.
    Acne causes profound negative psychological and social effects on the quality of life (QoL) of patients. The European Dermatology Forum S3-Guideline for the Treatment of Acne recommended adopting a QoL measure as an integral part of acne management. Because of constantly growing interest in health-related QoL assessment in acne and because of the high impact of acne on patients' lives, the European Academy of Dermatology and Venereology Task Force on QoL and Patient Oriented Outcomes and the Task Force on Acne, Rosacea and Hidradenitis Suppurativa have documented the QoL instruments that have been used in acne patients, with information on validation, purposes of their usage, description of common limitations and mistakes in their usage and overall recommendations. Read More

    Polyclonal hyperglobulinemia and elevated acute phase reactants in hidradenitis suppurativa.
    Br J Dermatol 2017 Sep 8. Epub 2017 Sep 8.
    Albert Einstein College of Medicine/ Montefiore Medical Center.
    Hidradenitis suppurativa (HS) is a chronic, painful inflammatory skin disease characterized by recurrent nodules and abscesses affecting intertriginous areas including the axilla, inframammary, and anogenital regions. Hurley staging (I-III) is commonly used to classify patients, with mild disease limited to inflammatory cystic nodules (stage I), that may be connected by isolated tunnels/sinuses (stage II), or form a network of bridging tunnels/sinuses (stage III) associated with odiferous, purulent drainage. The cause of HS is unknown but it is generally considered to be multifactorial. Read More

    SAPHO syndrome associated with hidradenitis suppurativa and pyoderma gangrenosum successfully treated with adalimumab and methotrexate: a case report and review of the literature.
    Int J Dermatol 2017 Sep 7. Epub 2017 Sep 7.
    Ingham Institute of Applied Medical Research, Liverpool, Sydney, Australia.
    SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome is a rare inflammatory condition describing the combination of skin, bone, and joint manifestations that has a heterogeneous presentation. We report a case of severe SAPHO syndrome in association with hidradenitis suppurativa and pyoderma gangrenosum in a 27-year-old male. The patient had an initial migratory arthritis affecting the knees, ankles, metacarpophalangeal joints, proximal interphalangeal joints, wrists, shoulder, and lower back, which progressed to a persistent arthritis and swelling at the sternum, shoulders, wrists, hands, feet, and lower back. Read More

    A Disease-Modifying Approach for Advanced Hidradenitis Suppurativa (Regimen with Metformin, Liraglutide, Dapsone, and Finasteride): A Case Report.
    Case Rep Dermatol 2017 May-Aug;9(2):70-78. Epub 2017 Jul 13.
    UNMC Department of Family Medicine, Nebraska Medical Center, Omaha, Nebraska, USA.
    Hidradenitis suppurativa (HS) is a challenging skin disease with limited therapeutic options. Obesity and metabolic syndrome are being increasingly implicated and associated with younger ages and greater metabolic severity. A 19-year-old female with an 8-year history of progressively debilitating cicatricial HS disease presented with obesity, profound anemia, leukocytosis, increased platelet count, hypoalbuminemia, and elevated liver enzymes. Read More

    Neutrophilic Eccrine Hidradenitis in an HIV-Infected Patient.
    Skinmed 2017 1;15(4):297-299. Epub 2017 Aug 1.
    Dermatology Division, Hospital General Dr. Manuel Gea González, Mexico City, Mexico.
    A 35-year-old man presented with a 2-day history of a maculopapular pruritic eruption that had affected his general state of health and was accompanied by chills. The patient had been diagnosed with HIV in 2008, and was undergoing treatment with a combination of emcitrabine/tenofovir plus nevirapine. He had a current viral load of 1,558,160 copies/mL and a lymphocyte count CD4+ count of 230/mm3. Read More

    Hidradenitis Suppurativa and Concomitant Down Syndrome: Literature Review of Other Associated Mucocutaneous Manifestations in Adults.
    Skinmed 2017 1;15(4):253-258. Epub 2017 Aug 1.
    DermatoVenereology (Skin/VD) Centre, Sehgal Nursing Home, Panchwati, Delhi, India.
    This contribution describes hidradenitis suppurativa (HS) occurring in Down disease that presented with morphology conforming to an overlap of stages 1 and 2 of the Hurley staging system, namely the formation of solitary or multiple isolated abscesses without scarring or sinus tracts, recurrent abscesses, and single or multiple widely separated lesions with sinus tract formation, occupying apocrine sweat gland-bearing areas: the inner thighs, groin, and buttocks. The lesions were bilateral and symmetrical, of rare occurrence. In addition, the clinical and pathognomonic features of several other concomitant diseases are defined and reviewed; these include elastosis perforans serpiginosa, fissured tongue/macroglossia, syringomas, palmoplantar keratodermas, cheilitis, xerosis, atopic dermatitis, seborrheic dermatitis, vitiligo, cutis marmorata, and alopecia areata. Read More

    IL-36 cytokines are increased in acne and hidradenitis suppurativa.
    Arch Dermatol Res 2017 Aug 29. Epub 2017 Aug 29.
    Department of Clinical Medicine and Surgery, University of Naples Federico II, Naples, Italy.
    Interleukin (IL)-36 cytokines are new members of the IL-1 family, which include pro-inflammatory factors, IL-36α, IL-36β and IL-36γ, and a natural receptor antagonist IL-36Ra. Over recent years, much has been learned on their important functions in the regulation of immune response and, especially, on their role in many inflammatory skin diseases. However, to date, no data have been reported on their possible involvement in acne and hidradenitis suppurativa (HS). Read More

    The Clinical Pattern of Axillary Hidradenitis Suppurativa among Saudi Arabians: Mode of Presentation and Treatment Challenges.
    J Cutan Aesthet Surg 2017 Apr-Jun;10(2):95-100
    Department of General Surgery, Al Ansar General Hospital, Medina, Saudi Arabia.
    Background: Hidradenitis suppurativa is a chronic follicular occlusive disease affecting the folliculopilosebaceous unit. The clinical course is variable, ranging from mild to severe cases. Definitive evidence-based guidelines for the management are lacking. Read More

    Disseminate recurrent folliculitis as the presenting picture of hidradenitis suppurativa.
    Ann Dermatol Venereol 2017 Aug 21. Epub 2017 Aug 21.
    11, chaussée de la Muette, 75016 Paris, France. Electronic address:
    Background: Hidradenitis suppurativa (HS) has a polymorphous clinical presentation. Herein we report two cases of HS revealed by disseminate recurrent folliculitis. PATIENTS AND METHODS CASE 1: A 31-year-old woman consulted for disseminate recurrent folliculitis on the trunk and proximal segments of the limbs that had been ongoing for several years. Read More

    Adipokines are dysregulated in patients with hidradenitis suppurativa.
    Br J Dermatol 2017 Aug 23. Epub 2017 Aug 23.
    St. Vincent's University Hospital, Department of Dermatology, Dublin, Ireland.
    Hidradenitis suppurativa (HS), is characterized by the appearance of painful subcutaneous nodules and dermal abscesses in the axillae, perineum and inframammary folds. The development of HS has been linked to factors such as cigarette smoking and obesity(1) . Patients with HS are more likely to have metabolic syndrome than control populations and develop early cardiovascular diseases(2) . Read More

    Moderate to severe hidradenitis suppurativa patients do not have an altered bacterial composition in peripheral blood compared to healthy controls.
    J Eur Acad Dermatol Venereol 2017 Aug 22. Epub 2017 Aug 22.
    Department of Dermatology, Zealand University Hospital, Health Sciences Faculty, University of Copenhagen, Roskilde, Denmark.
    Background: Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease defined by recurrent nodules, tunnels and scarring involving the intertriginous skin. Patients with HS often report an array of systemic symptoms such as fatigue and malaise. The aetiology of these symptoms remains unclear. Read More

    Recommendations for the management of comorbidity in hidradenitis suppurativa.
    J Eur Acad Dermatol Venereol 2017 Aug 10. Epub 2017 Aug 10.
    Aragonese Institute of Health Sciences, Miguel Servet University Hospital, University of Zaragoza, Zaragoza, Spain.
    Background: The association between hidradenitis suppurativa (HS) and some diseases is becoming relevant in recent years. Providing appropriate management of HS from an early stage requires to include prompt diagnosis and treatment of concomitant diseases and to prevent any potential comorbidity. This approach should consider the adverse events of the drugs used to treat HS potentially related to the onset of a comorbidity. Read More

    Factors predicting the self-evaluated health of hidradenitis suppurativa patients recruited from an outpatient clinic.
    J Eur Acad Dermatol Venereol 2017 Aug 10. Epub 2017 Aug 10.
    Dept. of Dermatology, University hospital Zealand, Roskilde, Denmark.
    Objectives: In recent years, Hidradenitis suppurativa has received increased attention, but still lack well-defined, robust patient reported outcome measures. Such measures are likely to be influenced by contextual factors. We therefore aim to describe the association of biological and other factors with HS patient's self-evaluated health as reflected by the EQ5D VAS score. Read More

    Hidradenitis suppurativa: an update on connecting the tracts.
    F1000Res 2017 28;6:1272. Epub 2017 Jul 28.
    Henry Ford Hospital Department of Dermatology, Detroit, MI, USA.
    Hidradenitis suppurativa (HS) is a devastating disease involving abscesses, sinus tracts, and inflammation classically affecting the axilla, groin, and/or anogenital region. Although the disease pathogenesis is not fully understood, recent advances suggest that HS pathology runs much deeper than the cutaneous manifestations. It is now believed that HS is a systemic inflammatory disease that gives rise to the characteristic cutaneous manifestations. Read More

    Hidradenitis suppurativa: A neglected disease in Indigenous Australians.
    Australas J Dermatol 2017 Aug 9. Epub 2017 Aug 9.
    Dermatology Research Group, Ingham Institute for Applied Medical Research, Sydney, New South Wales, Australia.
    We report the first case series of hidradenitis suppurativa in patients of Indigenous Australian heritage. The incidence and ethnicity of populations affected by this condition are not known. The high comorbid disease burden and socioeconomic disadvantage that is well recognised in the Indigenous Australian population poses significant challenges to therapeutic outcomes. Read More

    Hidradenitis suppurativa - Management, comorbidities and monitoring.
    Aust Fam Physician 2017 ;46(8):584-588
    Background: Hidradenitis suppurativa (HS) is a chronic inflammatory disease presenting in intertriginous areas. HS is associated with a number of disease-modifying comorbidities, including metabolic syndrome and androgen dysfunction, and smoking.

    Objective: This review provides a synopsis of the aetiology and diagnosis of HS, and an overview of management for this often devastating disease. Read More

    Severe Acne Inversa - Dermatosurgical Approach in a Bulgarian Patient.
    Open Access Maced J Med Sci 2017 Jul 24;5(4):561-563. Epub 2017 Jul 24.
    Medical Institute of Ministry of Interior (MVR), Department of Dermatology and Dermatologic Surgery, General Skobelev 79, 1606 Sofia, Bulgaria.
    We present a 55-year-old male patient - a smoker, admitted to a Medical Institute of MVR (Ministry of the interior, Sofia, Bulgaria), on occasion of pain and swellings, located in the area of both axillae, accompanied by purulent discharge, with bloody admixtures. Bilateral localised cystic rose above the skin surface, hyperpigmented nodules interconnected with multiple fistulas, was observed within the dermatological examination, resulting in a limitation of the possibility of movement of the hands in all directions. A subjective complaint of pain was obtained on palpation. Read More

    Challenging Ulcerative Vulvar Conditions: Hidradenitis Suppurativa, Crohn Disease, and Aphthous Ulcers.
    Obstet Gynecol Clin North Am 2017 Sep;44(3):453-473
    Total Dermatology Care Center P.A., 915 West Monroe Street, Suite 101, Jacksonville, FL 32204, USA. Electronic address:
    This article discusses the clinical evaluation and approach to patients with 3 complex ulcerative vulvar conditions: hidradenitis suppurativa, metastatic Crohn disease of the vulva, and aphthous ulcers. These conditions are particularly challenging to medical providers because, although each is known to present with nonspecific examination findings that vary in morphology, the predominance of the diagnosis is based on clinical examination and exclusion of a wide variety of other conditions. Care of patients with these conditions is further complicated by the lack of therapeutic data and the significant impact these conditions have on quality of life. Read More

    Palmar Eccrine Hidradenitis Secondary to Trauma from Computer Gaming in an Adolescent After Bone Marrow Transplantation.
    Pediatr Dermatol 2017 Sep 2;34(5):e283-e285. Epub 2017 Aug 2.
    Dermatology Service, KK Women's & Children's Hospital, Singapore City, Singapore.
    A 14-year-old boy who had undergone a matched sibling bone marrow transplant for acute lymphoblastic leukemia presented with painful nodules on his palms after prolonged gaming on his computer and mobile phone. Histology showed a neutrophilic inflammatory infiltrate surrounding the acrosyringium and eccrine sweat coils in the deep dermis. The lesions resolved spontaneously with conservative management. Read More

    Lymphocytic hidradenitis: A distinctive histopathological finding of annular erythema of Sjögren syndrome.
    Australas J Dermatol 2017 Aug 3. Epub 2017 Aug 3.
    College of Medicine, Chang Gung University, Taoyuan, Taiwan.
    Background/objectives: Lymphocytic hidradenitis is a non-specific histopathological feature observed in many dermatoses such as lupus erythematosus, morphea or scleroderma. When it occurs it is usually accompanied by the other distinctive histological features of those conditions. Isolated lymphocytic hidradenitis is uncommon and its clinical features and associated underlying medical conditions are still undetermined. Read More

    The Clinical Significance of Increased Serum Proinflammatory Cytokines, C-Reactive Protein, and Erythrocyte Sedimentation Rate in Patients with Hidradenitis Suppurativa.
    Mediators Inflamm 2017 10;2017:2450401. Epub 2017 Jul 10.
    Unidad de Gestión Clínica de Dermatología, Hospital Universitario Puerta del Mar, Cádiz, Spain.
    Objectives: To assess inflammatory serum markers including serum proinflammatory cytokines, C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR) according to the clinical inflammatory activity of patients with hidradenitis suppurativa (HS).

    Patients And Methods: Seventy-four patients with HS were studied based on the Hidradenitis Suppurativa-Physician Global Assessment (HS-PGA) score and Hurley staging system. Proinflammatory cytokines were measured using a multiplex cytokine assay. Read More

    Skin diseases of the vulva: inflammatory, erosive-ulcerating and apocrine gland diseases, zinc and vitamin deficiency, vulvodynia and vestibulodynia.
    J Obstet Gynaecol 2017 Aug 1:1-12. Epub 2017 Aug 1.
    a Department of Dermatology , Bispebjerg Hospital , Copenhagen , Denmark.
    Chronic, inflammatory and ulcerating mucocutaneous diseases that can affect the vulvar area are reviewed: lichen sclerosus, lichen planus, plasma cell vulvitis, complex aphthosis, Behcet's disease, pyoderma gangrenosum, metastatic Crohn's disease, dyskeratotic skin diseases (Hailey-Hailey disease and Darier's disease), autoimmune bullous diseases (mucous membrane pemphigoid and pemphigus vulgaris) and hidradenitis suppurativa. Also, vulvodynia and vestibulodynia, zinc and vitamin B deficiency are described. Read More

    Is the prevalence of hidradenitis suppurativa being overestimated in Europe? Or is the disease underdiagnosed? Evidence from a nationwide study across Portuguese public hospitals.
    Int J Dermatol 2017 Aug 1. Epub 2017 Aug 1.
    Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine, University of Porto, Porto, Portugal.

    Altered Global 5-Hydroxymethylation Status in Hidradenitis Suppurativa: Support for an Epigenetic Background.
    Dermatology 2017 Jul 28. Epub 2017 Jul 28.
    Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum, Bochum, Germany.
    Background: The pathogenesis of hidradenitis suppurativa (HS), with its complex inflammatory network, is still elusive. Imbalances in DNA methylation can lead to genome destabilization and have been assumed to play a role in inflammatory diseases. Global DNA methylation and hydroxymethylation have not been studied in HS yet. Read More

    The increasing relevance of biofilms in common dermatological conditions.
    J Dermatolog Treat 2017 Aug 9:1-6. Epub 2017 Aug 9.
    b Department of Dermatologic Surgery and Laser Unit, St. Thomas' Hospital , St. John's Institute of Dermatology , London , UK.
    Background: Biofilms are diverse groups of microorganisms encased in a self-produced matrix that offers protection against unfavorable conditions and antibiotics.

    Methods: We performed a literature search using the MEDLINE electronic database. Only original articles published in English were considered for review. Read More

    Patients with hidradenitis suppurativa have a high psychiatric disease burden: A Finnish nationwide registry study.
    J Invest Dermatol 2017 Jul 20. Epub 2017 Jul 20.
    PEDEGO Research Unit, University of Oulu; Department of Dermatology and Medical Research Center Oulu, Oulu University Hospital, Oulu, Finland. Electronic address:
    Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease of hair follicles which is associated with various comorbidities. In order further to clarify the associations between HS and psychiatric disorders, we conducted a nationwide retrospective study that included 4381 patients with HS and 39554 psoriasis and 43248 melanocytic nevi patients as controls. Patient data were obtained from the statutory Finnish Care Register for Health Care. Read More

    Inflammatory Joint Disorders and Neutrophilic Dermatoses: a Comprehensive Review.
    Clin Rev Allergy Immunol 2017 Jul 22. Epub 2017 Jul 22.
    Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Unità Operativa di Dermatologia, Università degli Studi di Milano, IRCCS Fondazione Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
    Rheumatoid arthritis and spondyloarthritis are inflammatory joint disorders with an autoimmune pathogenesis and systemic involvement. The skin is one of the most frequently affected extraarticular sites with a number of manifestations or distinct diseases, including common conditions, such as rheumatoid nodules and psoriasis, and rare diseases like neutrophilic dermatoses. The latter are clinically characterised by polymorphic lesions, including pustules, bullae, abscesses, papules, nodules, plaques and ulcers, and histologically by neutrophil-rich inflammatory infiltrates. Read More

    A pilot study of fatigue in patients with Hidradenitis suppurativa.
    Br J Dermatol 2017 Jul 22. Epub 2017 Jul 22.
    Zealand University Hospital, Department of Dermatology, Roskilde, Denmark.
    Patients suffering from Hidradenitis Suppurativa often complain of fatigue or tiredness, a common symptom in other chronic systemic inflammatory conditions.(1) Fatigue has been reported as a prodromal symptom in 32% of HS patients(1) , indicating that it is an important symptom in HS. This article is protected by copyright. Read More

    Hidradenitis Suppurativa in Children Treated with Finasteride-A Case Series.
    Pediatr Dermatol 2017 Sep 20;34(5):578-583. Epub 2017 Jul 20.
    Department of Dermatology, Centro Hospitalar do Porto, Porto, Portugal.
    Background: Hidradenitis suppurativa (HS) is rare in childhood, with only 2% of cases in patients younger than 11 years. It is a chronic, recurrent, debilitating condition for which no universally effective treatment has been developed. We present five cases of children with HS diagnosed between the ages of 6 and 11 years. Read More

    [Hidradenitis suppurativa - symptoms, diagnostics, and therapy].
    Cas Lek Cesk 2017 ;156(3):127-132
    Hidradenitis suppurativa is a chronic skin disorder characterized by recurrent inflammatory nodules, fistulas, abscesses, and scarring mainly in the intertriginous areas with terminal hair and apocrine glands. Hidradenitis suppurativa manifests usually after puberty, in the third life decade and persists for many years. The prevalence of the disease is estimated to be 0,5 % in the Czech Republic. Read More

    Treatment of hidradenitis suppurativa with rifampicin: have we forgotten tuberculosis?
    Br J Dermatol 2017 Jul 18. Epub 2017 Jul 18.
    Universidade do Porto Ringgold Standard Institution - EpiUnit, Institute of Public Health, Porto, Portugal.
    Hidradenitis suppurativa (HS) is a chronic, recurrent and debilitating skin disease of the hair follicle that is accompanied by systemic inflammation. Treating HS is challenging, and therapeutic tools as diverse as topical and systemic antibiotics, biologics, intralesional steroids, surgical procedures or light and laser therapies are frequently needed. The combination of oral clindamycin and rifampicin (R+C) has been suggested as a possible treatment regimen (level of evidence III, strength of recommendation C). Read More

    Considering the impact of pregnancy on the natural history of hidradenitis suppurativa.
    Br J Dermatol 2017 Jul 18. Epub 2017 Jul 18.
    Johns Hopkins Medical Institutions, Department of Dermatology.
    Hidradenitis suppurativa (HS) is a chronic and debilitating inflammatory skin disease that disproportionately affects women of childbearing age. Yet, little has been written about the impact of pregnancy on the natural history of HS. It has been postulated that apocrine-gland activity diminishes in pregnancy, accounting for symptom remission. Read More

    Clinical and histological changes in Hidradenitis suppurativa following 1064 nm nd:YAG intralesional laser treatment.
    J Biol Regul Homeost Agents 2017 APR-JUN;31(2 Suppl. 2):131-140
    Anatomic Pathologic, Department of Molecular Medicine, University of Pavia, Pavia, Italy.
    Hidradenitis Suppurativa (HS) is recently attracting much attention and awareness, often because it is misdiagnosed for years, restricting the therapeutic options. Moreover, this pathology arises in areas such as the inguinal region, that may cause embarrassment in young patients. Wrong diagnosis and delay in appropriate treatments lead to an exacerbation of the symptoms and a progression of the disease, which at the last stage can only be managed through extensive surgical excisions, ablation and vaporization of nodules with CO2 laser systems or aggressive chemotherapies such as anti-TNF-alpha like adalimumab (Humira®-AbbVie Inc. Read More

    Recognizing syndromic hidradenitis suppurativa: a review of the literature.
    J Eur Acad Dermatol Venereol 2017 Jul 11. Epub 2017 Jul 11.
    Department of Dermatology, Zealand University Hospital, Roskilde, Denmark.
    Hidradenitis suppurativa (HS) is an inflammatory skin disease causing painful inflammation and suppuration. It may occur in rare syndromes: follicular occlusion, Bazex-Dupré-Christol, Down's, KID, PAPASH, PASS, PASH, and SAPHO syndromes, as well as Dowling-Degos disease. An overview of syndromic HS may inform the search for aetiological factors in HS. Read More

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