2,221 results match your criteria Neutrophilic Eccrine Hidradenitis
J Dtsch Dermatol Ges 2018 Jun 22. Epub 2018 Jun 22.
Department of Dermatology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Dig Endosc 2018 Jun 22. Epub 2018 Jun 22.
Division of Gastroenterology, Matsuyama Red Cross Hospital, Ehime, Japan.
A 54-year-old man was referred to our hospital because of 2 years' duration of extended multiple nodules with abscess and fistula with pus discharge in the gluteal and perianal regions (Fig. 1a). Laboratory data identified inflammatory reaction (WBC, 11430 /μl, and C-reactive protein, 4. Read More
Br J Dermatol 2018 Jun 22. Epub 2018 Jun 22.
Department of Dermatology, Venereology and Allergy, University Medical Center and Medical Faculty Mannheim, Heidelberg University.
Dowling-Degos disease (DDD) is a rare autosomal dominant genodermatosis, that clinically indistinguishable from its acantholytic variant Galli-Galli disease (GGD) presents with reticulate pigmentation but also erythematous to brown hyperkeratotic papules mainly in flexural and intertrigineous areas. KRT5 , POGLUT1 , POFUT1 and PSENEN mutations were identified as underlying causative genetic defects in DDD. Interestingly in patients with PSENEN mutations DDD is often associated with hidradenitis suppurativa. Read More
JAMA Dermatol 2018 Jun 20. Epub 2018 Jun 20.
Department of Dermatology, Venereology and Allergology, Ruhr-University Bochum, Bochum, Germany.
JAMA Dermatol 2018 Jun 20. Epub 2018 Jun 20.
Psoriasis Research and Treatment Center, Clinic of Dermatology, Venereology, and Allergology and Institute of Medical Immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Rev Col Bras Cir 2018 18;45(3):e1719. Epub 2018 Jun 18.
Hospital das Clínicas, School of Medicine, University of São Paulo, São Paulo, SP, Brazil.
Objective: to evaluate the primary outcome of local complications and late recurrence in patients with hidradenitis suppurativa undergoing radical resection and specific reconstruction.
Methods: we conducted a retrospective analysis of the medical records of patients attended by the Plastic Surgery Service of the Clinics Hospital, Medical School, USP, between 2010 and 2016. We included patients who underwent radical resection of hidradenitis suppurativa in advanced stage and reconstruction through primary closure, grafts or flaps. Read More
Front Med (Lausanne) 2018 25;5:115. Epub 2018 Apr 25.
Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Non-invasive bedside imaging tools are becoming more prevalent for assessing cutaneous lesions. Ultrasound used at specific frequencies allows us to assess margins of lesions to minimize the extent of the biopsy that is performed and improve cosmetic outcomes. Vascularity, seen on Doppler ultrasound and contrast-enhanced ultrasound, and stiffness, assessed on tissue elastography, can help differentiate between benign and malignant lesions for clinicians to be more judicious in deciding whether to biopsy. Read More
SAGE Open Med Case Rep 2018 1;6:2050313X18778723. Epub 2018 Jun 1.
SKiN Centre for Dermatology, Peterborough, ON, Canada.
Introduction: Hidradenitis suppurativa and synovitis, acne, pustulosis, hyperostosis, osteitis syndrome are chronic, debilitating diseases involving apocrine gland-bearing skin inflammation and bone inflammation, respectively. Although both often present with multiple comorbidities, single patient co-presentation is rare.
Methods/results: This study reports the 8-year treatment course of a 40-year-old man with hidradenitis suppurativa and synovitis, acne, pustulosis, hyperostosis, osteitis syndrome, and reviews relevant literature. Read More
Int J Dermatol 2018 Jun 16. Epub 2018 Jun 16.
Dermatology and Venereology Department, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.
Background: Multiple treatment modalities were introduced for treatment of hidradenitis suppurativa (HS) but mostly with unsatisfactory results.
Objective: In this prospective randomized right-left intra-individual controlled study, we studied the safety and efficacy of combined treatment with fractional CO laser and long pulsed Nd : YAG (1064 nm) laser in treatment of HS.
Methods: Twenty adult patients with HS were randomized into this study. Read More
Dermatol Online J 2018 Apr 15;24(4). Epub 2018 Apr 15.
Division of Dermatology, Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Many cases of superinfected hidradenitis suppurativa (HS) involve multiple species of bacteria, but gas-producing infections are rare and can complicate the clinical picture. Additionally, recognizing squamous cell carcinoma (SCC) as a complication of longstanding HS is imperative. Herein, we present a unique case of a severe emphysematous HS that was initially mistaken for Fournier gangrene and eventually diagnosed as superinfected SCC. Read More
J Dermatol 2018 Jun 13. Epub 2018 Jun 13.
Department of Dermatology, Rambam Health Care Campus, Technion, Haifa, Israel.
Staphylococcus lugdunensis is an emerging pathogen in skin and soft tissue infections that was previously considered a commensal. The aim of this study was to elucidate the characteristics of skin infections by S. lugdunensis and its appropriate management, in a tertiary referral medical center. Read More
J Eur Acad Dermatol Venereol 2018 Jun 12. Epub 2018 Jun 12.
Clinica Dermatologica, Dipartmento di Scienze Mediche e Sanità Pubblica, Università di Cagliari, Cagliari, Italy.
Hidradenitis suppurativa (HS) is a chronic relapsing inflammatory dermatosis of the body folds, characterized by nodules, abscesses, sinus tracts and numerous comorbidities, significantly impairing patients quality of life (QoL). Among skin diseases, HS has the largest impact on QoL . Few specific instruments are available to assess, in a comprehensive, psychosocial perspective, the burden of HS , and no qualitative studies exploring the experience of HS patients and their relationship with the physician are currently available. Read More
JAAD Case Rep 2018 Jul 6;4(6):543-545. Epub 2018 Jun 6.
Department of Dermatology, University of Pittsburgh, Pittsburgh, Pennsylvania.
Clin Exp Dermatol 2018 Jun 11. Epub 2018 Jun 11.
Dr V. K. Jain Skin Center, Rohtak, Haryana, India.
Int J Rheum Dis 2018 May;21(5):1018-1022
Division of Rheumatology, School of Medicine and Health Sciences, Ideas to Health Laboratory, The George Washington University, Washington, District of Columbia, USA.
Aim: The purpose of this study was to investigate the prevalence of antinuclear antibody (ANA) positivity in a cohort of patients with hidradenitis suppurativa (HS), and to assess the frequency of seroconversion during treatment with tumor necrosis factor (TNF)-α inhibitor therapy.
Methods: This prospective study was conducted through the Wound Etiology and Healing (WE-HEAL) Study. Immunofluorescence ANA testing was performed at baseline, and repeated when clinically indicated. Read More
Br J Clin Pharmacol 2018 Jun 7. Epub 2018 Jun 7.
Centre for Human Drug Research, Leiden, the Netherlands.
Aims: To explore the potential of the skin microbiome as biomarker in six dermatological conditions i.e. atopic dermatitis (AD), acne vulgaris (AV), psoriasis vulgaris (PV), hidradenitis suppurativa (HS), seborrheic dermatitis/pityriasis capitis (SD/PC) and ulcus cruris (UC). Read More
Int J Womens Dermatol 2018 Jun 5;4(2):72-73. Epub 2018 Apr 5.
Department of Dermatology, Zealand University Hospital, Roskilde, Denmark.
Int J Womens Dermatol 2018 Mar 12;4(1):27-31. Epub 2017 Dec 12.
Ann & Robert H. Lurie Children's Hospital, Chicago, IL.
Background: Pediatric skin disorders can affect children's self-esteem, relationships with caregivers and peers, and performance in school and activities.
Objective: This review describes common pediatric congenital and acquired dermatologic disorders and the impact that these disorders can have on children's self-esteem.
Methods: A review of current, English-language literature was conducted with use of the PubMed database. Read More
Actas Dermosifiliogr 2018 Jun 2. Epub 2018 Jun 2.
Servicio de Dermatología, IIS-FIB, Hospital Universitario de La Princesa. Madrid, España.
Patients with chronic inflammatory diseases being treated with immunosuppressive drugs, and with tumor necrosis factor inhibitors in particular, have an increased risk of infection by Mycobacterium tuberculosis. Screening for latent tuberculosis infection and preventive therapy to reduce the risk of progression to active tuberculosis are mandatory in this group of patients. This updated multidisciplinary consensus document presents the latest expert opinions on the treatment and prevention of tuberculosis in candidates for biologic therapy and establishes recommendations based on current knowledge relating to the use of biologic agents. Read More
J Cutan Med Surg 2018 May/Jun;22(3):369-371
J Cutan Med Surg 2018 May/Jun;22(3):368
J Am Acad Dermatol 2018 May 31. Epub 2018 May 31.
Department of Dermatology, Zealand University Hospital, Health Sciences Faculty, University of Copenhagen, Roskilde, Denmark.
Background: The long-term optimal dosing strategy for adalimumab in hidradenitis suppurativa/acne inversa (HS) was evaluated by pooling the results of the PIONEER phase 3 trials and an open-label extension (OLE) study.
Objective: To assess response and tolerability of long-term adalimumab in HS.
Methods: The durations of PIONEER I/II periods A, B, and OLE were 12, 24, and ≥ 52 weeks, respectively. Read More
Case Rep Dermatol Med 2018 16;2018:8685136. Epub 2018 Apr 16.
Department of Dermato-Venereology and Wound Healing Centre, Bispebjerg Hospital, Copenhagen, Denmark.
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disorder involving primarily the intertriginous skin of the axillary, inguinal, genital, and perianal areas of the body. It is characterized by recurrent inflamed nodules and abscesses, resulting in fistulae, fibrosis, and scarring. We present a case of HS refractory to local and systemic antibiotic therapy as well as anti-TNF and anti-IL12/23 that was successfully treated with secukinumab (anti-IL17A). Read More
Plast Surg Nurs 2018 Apr/Jun;38(2):46-47
Courtney Kendall, BSN, RN, is a graduate Nurse Practitioner student at Virginia Commonwealth University, completing her final clinic practicum in the Plastic and Reconstructive Surgery department at VCU Health, Richmond, Virginia.
Hidradenitis suppurativa (HS) is a painful and debilitating, chronic inflammatory disease affecting the skin bearing apocrine glands. HS causes painful abscesses and nodules that can eventually progress to interconnected sinus tracts, scarring, and contractures of the skin. There is no definitive cure for HS, but multiple treatment strategies are available to patients. Read More
Actas Dermosifiliogr 2018 May 23. Epub 2018 May 23.
Departamento de Dermatología y Venereología, Centro Hospitalario de São João, Oporto, Portugal; Departamento de Farmacología y Terapéutica, Facultad de Medicina, Universidad de Oporto, Oporto, Portugal.
JAMA Dermatol 2018 May 23. Epub 2018 May 23.
Department of Dermatology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, New Hyde Park, New York.
Importance: Limited evidence supports a link between hidradenitis suppurativa (HS) and Crohn disease (CD), and this relationship has not been established in the United States.
Objective: To evaluate the prevalence of CD among patients with HS in the United States and to determine the strength of association between the 2 conditions.
Design, Setting, And Participants: Cross-sectional analysis of data from 51 340 patients with HS identified using electronic health records data in the Explorys multiple health system data analytics and research platform, which includes data from more than 50 million unique patients across all US census regions. Read More
J Am Acad Dermatol 2018 May 19. Epub 2018 May 19.
AbbVie Inc., North Chicago, IL, USA.
Clin Exp Dermatol 2018 May 21. Epub 2018 May 21.
Department of Dermatology, Roskilde Hospital, Roskilde, Denmark.
Background: Hidradenitis suppurativa (HS) is a chronic inflammatory disease. Numerous studies have associated HS with obesity, and recently with metabolic syndrome (MetS). Both obesity and MetS are linked with metabolic changes. Read More
Turkiye Parazitol Derg 2018 May 21. Epub 2018 May 21.
Department of Endocrinology, Ankara Yıldırım Beyazıt University, Yenimahalle Training and Research Hospital, Ankara, Turkey.
Hidradenitis suppurativa (HS) is a chronic inflammatory skin disease. This type of dermatosis with underlying chronic inflammation significantly affects the quality of life and may be accompanied by many comorbidities. In this case, Demodex spp. Read More
Int J Dermatol 2018 May 17. Epub 2018 May 17.
Department of Dermatology, Henry Ford Hospital, Detroit, MI, USA.
Background: A paucity of knowledge exists regarding the use of ertapenem in hidradenitis suppurativa. Our retrospective chart review and telephone interview aims to investigate the utility of intravenous ertapenem in severe, refractory hidradenitis suppurativa.
Methods: This retrospective chart review and telephone interview included patients with severe, refractory hidradenitis suppurativa treated with intravenous ertapenem between March 2013 and December 2016. Read More
Singapore Med J 2018 May 18. Epub 2018 May 18.
Department of Dermatology, National Skin Centre, Singapore.
Introduction: Cigarette smoking is a leading cause of morbidity and mortality, and has a deleterious effect on dermatological conditions, such as skin cancers, hidradenitis suppurativa and psoriasis. The study aimed to evaluate the efficacy of a pharmacist-led smoking cessation clinic in reducing cigarette smoking at a tertiary referral dermatology centre. We describe the impact of this clinic to provide guidance on how such a model could be further improved and implemented more widely. Read More
Ann Vasc Surg 2018 Jun 18. Epub 2018 Jun 18.
OhioHealth Vascular Institute, OhioHealth Heart and Vascular Physicians, Columbus, OH. Electronic address:
Background: Chronic venous insufficiency (CVI) is a widely prevalent condition. Saphenous venous reflux is the most common underlying pathology that leads to CVI. Endovenous thermal ablations (ETA) are the current gold standard. Read More
Med Gas Res 2018 Jan-Mar;8(1):29-33. Epub 2018 Apr 18.
Department of Physiology and Biophysics, Stony Brook University School of Medicine, Stony Brook, NY, USA.
Hyperbaric oxygen therapy (HBOT) is a medical technique which delivers oxygen at ambient pressures to increase the amount of dissolved oxygen in the blood and oxygen distribution to tissues. There are several beneficial properties of HBOT concomitant with elevated oxygen distribution in tissue including anti-inflammation, angiogenesis through vascular endothelial growth factor proliferation, augmented fibroblast activity through fibroblast growth factor proliferation, tissue and wound repair, enhancement of lymphocyte and macrophage activity, increased male testosterone secretion, and bactericidal activity. Given its renown in treating conditions such as decompression sickness and carbon monoxide poisoning, HBOT is making gradual strides for use in genitourinary medicine due to its low risk and likeliness to achieve favorable results. Read More
ANZ J Surg 2018 May 15. Epub 2018 May 15.
Department of General Surgery, Singapore General Hospital, Singapore.
Photodiagnosis Photodyn Ther 2018 May 12. Epub 2018 May 12.
Faculty of Dentistry, Department of Dentistry, Reims University Hospital, Reims, France; GRESPI, EA 4694, Research Group in Engineering Sciences, University of Reims, Reims, France.
Hidradenitis suppurativa (HS) is a chronic, inflammatory, and recurrent skin disease. Surgical excision of wounds appears to be the only curative treatment for the prevention of recurrence of moderate to severe stages. Magnetic resonance imaging (MRI) is a standard reference examination for the detection of HS peri-anal inflammatory fistula. Read More
J Eur Acad Dermatol Venereol 2018 May 15. Epub 2018 May 15.
Department of Dermatology, St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Suwon, Korea.
Background: The prevalence of hidradenitis suppurativa (HS) in Asia is unknown. The associations between HS and other autoimmune disorders have rarely been reported.
Objective: We sought to determine the prevalence of and diseases associated with HS using the National Health Insurance (NHI) database. Read More
Dermatology 2018 May 14:1-8. Epub 2018 May 14.
Department of Dermatology, Inselspital, Bern University Hospital, Bern, Switzerland.
Background: Hidradenitis suppurativa (HS) is one of the most distressing conditions observed in dermatology and has a substantial negative effect on the quality of life of affected persons.
Objectives: The aim of this study was to evaluate different treatment strategies in patients with HS.
Methods: In a retrospective cohort, all patients with HS (July 2015 to March 2017) were reviewed. Read More
Acta Derm Venereol 2018 May 14. Epub 2018 May 14.
Department of Dermatology, Venereology and Allergology, Wroclaw Medical University, Chałubińskiego 1, 50-368 Wrocław, Poland.
There is a lack of data evaluating the influence of hidradenitis suppurativa-related subjective symptoms on sleep quality. The aim of this study was to assess the influence of itch and pain on sleep quality in 108 patients with hidradenitis suppurativa compared with 50 controls. The Athens Insomnia Scale (AIS) and Pittsburgh Sleep Quality Index (PSQI) were used to evaluate a spectrum of sleep disturbances. Read More
Semin Arthritis Rheum 2018 Mar 20. Epub 2018 Mar 20.
Department of Rheumatology and Clinical Immunology, University Medical Center Groningen, Groningen, The Netherlands; Department of Rheumatology, Medical Center Leeuwarden, Leeuwarden, The Netherlands.
Background: Spondyloarthritis (SpA), a chronic inflammatory, rheumatic disease, and hidradenitis suppurativa (HS), a chronic, debilitating, inflammatory skin disease, share several clinical and pathophysiological features, such as the association with inflammatory bowel disease and elevated cytokine levels IL-17 and TNF-α. Recently, SpA was reported to be more prevalent (2.3-28. Read More
Exp Dermatol 2018 May;27 Suppl 1:5-32
Br J Dermatol 2018 May 9. Epub 2018 May 9.
Department of Dermatology, Venereology and Allergology, Wrocław Medical University, Chałubińskiego 1, 50-368, Wrocław, Poland.
Hidradenitis suppurativa (HS) influences patients' lives in many ways. The most troublesome symptom of HS is chronic pain, of mild-to-moderate intensity, which is reported by almost all patients. With reference to psychosocial evaluation, HS appears to be a highly debilitating disease. Read More
Asia Pac J Clin Nutr 2018 ;27(3):728-734
Department of Surgery, Japan Community Healthcare Organization Yokohama Central Hospital, Yokohama, Japan.
Background And Objectives: Severe infection, inadequate food intake, and pressure ulcers in patients with type 2 diabetes can result in malnutrition. We describe a case in which rehabilitation nutrition was effective for treat-ing a pressure ulcer in a malnourished patient with type 2 diabetes.
Methods And Results: A 58-year-old man with type 2 diabetes was diagnosed with hidradenitis suppurativa on the left buttock and thigh and a severe pres-sure ulcer on his left kneecap. Read More
J Pediatr 2018 May 2. Epub 2018 May 2.
Department of Health Sciences University of Florence Anna Meyer Children's University Hospital Florence, Italy.
J Eur Acad Dermatol Venereol 2018 May 5. Epub 2018 May 5.
Department of Dermatology, Venereology and Allergology, Wrocław Medical University, Wrocław, Poland.
According to results of a recent literature search performed by the European Academy of Dermatology and Venereology (EADV) Task Forces (TF) on Quality of Life and Patient Oriented Outcomes (QoL and PO) and Acne, Rosacea and Hidradenitis Suppurativa (ARHS), most of the publications where health-related (HR) QoL of acne patients was studied were clinical trials. Members of the EADV TF on QoL and PO decided to detect which acne treatment has the best influence on HRQoL of acne patients. A new literature search was organized to find publications on acne treatment where the HRQoL of patients was assessed as an outcome measure. Read More
J Eur Acad Dermatol Venereol 2018 May 5. Epub 2018 May 5.
Department of Medical Sciences, Section of Dermatology, University of Ferrara, Ferrara, Italy.
Background: Hidradenitis Suppurativa (HS) is a chronic, highly debilitating disease. Few questionnaires have been developed to identify potential HS cases based on simple questions. A visual representation may help in characterising these lesions. Read More
Cutis 2018 Mar;101(3):163;164;176
Department of Dermatology, University of California, San Francisco, USA.
Front Immunol 2018 16;9:639. Epub 2018 Apr 16.
Department of Pathology, Erasmus Medical Center Rotterdam, Rotterdam, Netherlands.
The complement system is a fundamental part of the innate immune system, playing a crucial role in host defense against various pathogens, such as bacteria, viruses, and fungi. Activation of complement results in production of several molecules mediating chemotaxis, opsonization, and mast cell degranulation, which can contribute to the elimination of pathogenic organisms and inflammation. Furthermore, the complement system also has regulating properties in inflammatory and immune responses. Read More
Photodiagnosis Photodyn Ther 2018 Jun 27;22:251-252. Epub 2018 Apr 27.
First Affiliated Hospital of PLA General Hospital, China. Electronic address:
Hidradenitis suppurativa/acne inversa (HS/AI) is a type of chronic suppurative inflammatory reaction of the hair follicles characterized by recurrent dermal abscesses, sinus tracts and scars. So far, there has not been any prospective study proving the efficacy and safety of photodynamic therapy for the disease. In this report, one case of HS/AI achieved resolution of skin lesions, ulcer healing and disappearance of symptoms after nine treatments with 5-aminolevulinic acid photodynamic therapy (ALA-PDT). Read More
Ann Dermatol Venereol 2018 May 26;145(5):331-338. Epub 2018 Apr 26.
ResoVerneuil, France; Service de dermatologie, polyclinique Courlancy, 38 bis, rue de Courlancy, 51100 Reims, France.
Objective: To provide physicians with an understanding of the factors behind significant delays in the diagnosis of hidradenitis suppurativa (HS) in France.
Patients And Methods: This prospective multicentre national study conducted from October 2015 to March 2016 included all patients consulting for HS. Patient data were collected by means of a standardized questionnaire. Read More
Dermatol Surg 2018 May;44(5):714-720
All authors are affiliated with the Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.
Background: Although insulated intralesional radiofrequency ablation (IL-RFA) is being increasingly used in other specialties, not much information on its safety and efficacy in dermatology is available.
Objective: To describe our experience with insulated IL-RFA for various dermatological conditions.
Methods: This is a retrospective review of the patients who underwent IL-RFA in the past 3 years. Read More