Brain Stimul 2022 Mar-Apr;15(2):458-471. Epub 2022 Feb 26.
Department of Biomedical Engineering, Columbia University, New York, NY, 10027, USA; Department of Radiology, Columbia University Irving Medical Center, New York, NY, 10032, USA; Department of Electrical Engineering, Columbia University, New York, NY, 10027, USA; Data Science Institute, Columbia University, New York, NY, 10027, USA. Electronic address:
Background: Transcranial magnetic stimulation (TMS) is a non-invasive neuromodulation modality that can treat depression, obsessive-compulsive disorder, or help smoking cessation. Research suggests that timing the delivery of TMS relative to an endogenous brain state may affect efficacy and short-term brain dynamics.
Objective: To investigate whether, for a multi-week daily treatment of repetitive TMS (rTMS), there is an effect on brain dynamics that depends on the timing of the TMS relative to individuals' prefrontal EEG quasi-alpha rhythm (between 6 and 13 Hz). Read More