2,636 results match your criteria Neurological History and Physical Examination


A physician survey of poststroke aphasia diagnosis and treatment in China: SPEECH study.

Medicine (Baltimore) 2021 Jun;100(22):e25833

Drug Development Organization, Lundbeck China, Beijing, China.

Abstract: The current status of the diagnosis and management of poststroke aphasia (PSA) in China is unknown.To analyze the physicians' strategy and knowledge about the management of PSA in clinical practice and the needs for standardization of diagnosis and treatment.This survey was conducted in March-August 2019 at 32 tertiary hospitals in 16 provinces/municipalities in China. Read More

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Fatigue After Aneurysmal Subarachnoid Hemorrhage: Clinical Characteristics and Associated Factors in Patients With Good Outcome.

Front Behav Neurosci 2021 12;15:633616. Epub 2021 May 12.

Department of Neurosurgery, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.

Fatigue after aneurysmal subarachnoid hemorrhage (post-aSAH fatigue) is a frequent, often long-lasting, but still poorly studied sequel. The aim of the present study was to characterize the nature of post-aSAH fatigue with an itemized analysis of the Fatigue Severity Scale (FSS) and Mental Fatigue Scale (MFS). We further wanted to assess the association of fatigue with other commonly observed problems after aSAH: mood disorders, cognitive problems, health-related quality of life (HRQoL), weight gain, and return to work (RTW). Read More

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Mental health education in undergraduate medical curricula across Nepalese universities.

BMC Med Educ 2021 May 28;21(1):304. Epub 2021 May 28.

Department of Psychiatry and Mental Health, Institute of Medicine, Tribhuvan University, Kathmandu, Nepal.

Background: Mental and substance use disorders account for 30 % of the non-fatal disease burden and 10 % of the overall disease burden but the treatment gap is daunting. With just one psychiatrist per 200,000 populations in Nepal, the only convincing way to improve access to the services quickly is by mobilizing non-specialized medical practitioner. A robust mental health component within the training curriculum of general medical doctors could produce medical graduates with adequate knowledge and skills to deliver basic mental health service. Read More

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6-month multidisciplinary follow-up and outcomes of patients with paediatric inflammatory multisystem syndrome (PIMS-TS) at a UK tertiary paediatric hospital: a retrospective cohort study.

Lancet Child Adolesc Health 2021 May 24. Epub 2021 May 24.

Department of Paediatric Infectious Diseases, Great Ormond Street Hospital, London, UK; UCL Great Ormond Street Institute of Child Health, University College London, London, UK. Electronic address:

Background: Paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) is a new, rare, post-infectious complication of SARS-CoV-2 infection in children. We aimed to describe the 6-month outcomes of PIMS-TS.

Methods: This retrospective cohort study comprised children (aged <18 years) who fulfilled the UK Royal College of Paediatrics and Child Health (RCPCH) diagnostic criteria for PIMS-TS and were admitted to Great Ormond Street Hospital (London, UK) between April 4 and Sept 1, 2020. Read More

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Neutrophil-to-Lymphocyte Ratio on Admission is an Independent Risk Factor for the Severity of Neurological Impairment at Disease Onset in Patients with a First Episode of Neuromyelitis Optica Spectrum Disorder.

Neuropsychiatr Dis Treat 2021 18;17:1493-1503. Epub 2021 May 18.

Department of Neurology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, People's Republic of China.

Purpose: To investigate the relationship between the neutrophil-to-lymphocyte ratio (NLR) and the severity of neurological impairment at disease onset in patients with a first episode of neuromyelitis optica spectrum disorder (NMOSD).

Patients And Methods: This retrospective study included 259 patients with newly diagnosed NMOSD who were hospitalized at our institution between January 2013 and January 2020 (NMOSD group) and 169 healthy control subjects who underwent a physical examination at our hospital during the same period (control group). The clinical data collected included general information, past medical history, biochemical test results, imaging findings, NLR, AQP-4 antibody status, and initial Expanded Disability Status Scale score. Read More

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[Hemiparkinsonism-Hemiatrophy Syndrome with Hypoperfusion in Basal Ganglia: A Case Report].

Sichuan Da Xue Xue Bao Yi Xue Ban 2021 May;52(3):531-533

Department of Neurology, West China Hospital, Sichuan University, Chengdu 610041, China.

The patient, a 25-year-old woman, was seen at our hospital 6 years ago, complaining of weakness and stiffness in the left side of the body and left limbs for 1 years. Physical examination revealed atrophy of the upper and lower limbs on the left side. Neurological examination showed increased muscle tone in the left-side body and limbs, bradykinesia, decreased muscle strength in the left-side body and limbs, and positive Hoffman's sign in the left limbs. Read More

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ACR Appropriateness Criteria® Syncope.

J Am Coll Radiol 2021 May;18(5S):S229-S238

Specialty Chair, UT Southwestern Medical Center, Dallas, Texas, Chief, Cardiothoracic Imaging, UT Southwestern, Member BOD, SCCT, Editor, Radiology - Cardiothoracic Imaging.

Syncope and presyncope lead to well over one million emergency room visits in the United States each year. Elucidating the cause of syncope or presyncope, which are grouped together given similar etiologies and outcomes, can be exceedingly difficult given the diverse etiologies. This becomes more challenging as some causes, such as vasovagal syncope, are relatively innocuous while others, such as cardiac-related syncope, carry a significant increased risk of death. Read More

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[UPOINT phenotypic classification of a sample of female patients with bladder pain syndrome: Results of a national multicentric observational study.]

Arch Esp Urol 2021 May;74(4):369-382

Sección de Urología Reconstructiva y Funcional. Servicio de Urología. Hospital Universitario y Politécnico La Fe. Valencia. España.

Objectives: To study the possibility of classifying patients with BPS by UPOINT phenotypes and their correlation with the results of different BPS diagnostic tools. MATERIAL AND METHODS: Epidemiological, observational, longitudinal and multicentric study performed according to clinical practice. A total of 319 women with BPS were included, 79 with new diagnosis and 240 in follow-up. Read More

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Acute Severe Hyponatremia Following Use of "Detox Tea".

Cureus 2021 Mar 30;13(3):e14184. Epub 2021 Mar 30.

Adult Intensive Care Unit, John Radcliffe Hospital, Oxford University Hospitals National Health Service Foundation Trust, Oxford, GBR.

A previously healthy 51-year-old woman presented to the ED with a one-week history of malaise, myalgia, unsteadiness, and an intermittent mild headache. Physical examination revealed neurological signs including a broad-based gait and bilateral low amplitude tremor. Laboratory testing of electrolytes revealed acute severe hyponatremia (115 mmol/L). Read More

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Evaluation of the Etiology, Clinical Presentation, Findings and Prophylaxis of Children with Headache.

Authors:
Betul Kilic

Sisli Etfal Hastan Tip Bul 2021 17;55(1):128-133. Epub 2021 Mar 17.

Department of Pediatric Neurology, University of Health Sciences Turkey Faculty of Medicine, Kocaeli Derince Training and Research Hospital, Kocaeli, Turkey.

Objectives: A headache is prevalent in childhood and constitutes a significant part of outpatient applications. This study aimed to evaluate the results of etiology, clinical features, examination results, prophylactic treatment and follow-up in patients with a headache.

Methods: Between January 2017 and December 2018, the files of the patients with the complaint of headache were reviewed retrospectively in this study. Read More

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Significant Impact of Coffee Consumption on MR-Based Measures of Cardiac Function in a Population-Based Cohort Study without Manifest Cardiovascular Disease.

Nutrients 2021 Apr 13;13(4). Epub 2021 Apr 13.

Department of Radiology, University Hospital, LMU Munich, 81377 Munich, Germany.

Subclinical effects of coffee consumption (CC) with regard to metabolic, cardiac, and neurological complications were evaluated using a whole-body magnetic resonance imaging (MRI) protocol. A blended approach was used to estimate habitual CC in a population-based study cohort without a history of cardiovascular disease. Associations of CC with MRI markers of gray matter volume, white matter hyperintensities, cerebral microhemorrhages, total and visceral adipose tissue (VAT), hepatic proton density fat fraction, early/late diastolic filling rate, end-diastolic/-systolic and stroke volume, ejection fraction, peak ejection rate, and myocardial mass were evaluated by linear regression. Read More

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Fibrous Dysplasia of the Spine-A Case Involving the Polyostotic Form Isolated to the Thoracolumbar Spine.

Int J Spine Surg 2021 Feb 29;14(s4):S46-S51. Epub 2020 Dec 29.

Department of Orthopaedics and Traumatology, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia.

Fibrous dysplasia of the spine in a polyostotic form is very rare, with fewer than 36 cases discussed in the literature and there is no such case in Indonesia that has been reported. The aim of this report is to present a case from Indonesia of polyostotic fibrous dysplasia isolated in the spine. We report a case of a 38-year-old Sundanese man with a 1-year history of progressive back pain and weakness of both lower extremities. Read More

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February 2021

Case of paediatric catatonia precipitated by antipsychotic withdrawal in a child with autism spectrum disorder.

BMJ Case Rep 2021 Apr 23;14(4). Epub 2021 Apr 23.

Child and Adolescent Mental Health Services, Unit 6 Quin Road Business Park, Ennis, Ireland.

A 13-year-old girl with moderate intellectual disability and autism spectrum disorder (ASD) was admitted to the paediatric high-dependency unit following an 8-week history of altered mental status and motor behaviour. Her symptoms emerged followed shortly after discontinuation of risperidone, an atypical antipsychotic previously commenced to manage disruptive behaviour associated with ASD. On physical examination, the patient presented with negativism, grimacing, automatic obedience, waxy flexibility and ambitendency. Read More

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Brain Ependymoma in an African Grey Parrot ().

J Avian Med Surg 2021 Apr;35(1):75-79

FauneVET, 22 rue René Viviani 44200 Nantes, France.

A 14-year-old unsexed African grey parrot () was presented with a 12-hour history of neurological signs and vomiting. The external physical examination of the patient revealed lethargy, moderate hypothermia, a head tilt, and horizontal nystagmus. Whole-body radiographic imaging and blood biochemistry parameters were unremarkable, and a serological test to detect bornavirus was negative. Read More

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Neurological manifestations of patients with mild-to-moderate COVID-19 attending a public hospital in Lima, Peru.

eNeurologicalSci 2021 Jun 14;23:100338. Epub 2021 Apr 14.

Epidemiology, STD, and HIV Unit, School of Public Health and Administration, Universidad Peruana Cayetano Heredia, Lima, Peru.

Objective: To determine the prevalence and characteristics of the most common neurological manifestations in Peruvian patients with mild-to-moderate COVID-19.

Methods: We conducted a single-center prospective, cross-sectional study at an isolation center functioning as a public acute-care hospital during the COVID-19 pandemic in Lima, the capital city of Peru. This was a convenience sample of patients with acute COVID-19 infection and mild-to-moderate respiratory symptoms who presented for hospital admission between September 25 and November 25, 2020. Read More

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Bell's Palsy as a Late Neurologic Manifestation of COVID-19 Infection.

Cureus 2021 Mar 14;13(3):e13881. Epub 2021 Mar 14.

Internal Medicine, Reading Hospital - Tower health, West Reading, USA.

Bell's palsy is acute peripheral facial nerve palsy; its cause is often unknown but it can be triggered by acute viral infection. Coronavirus disease 2019 (COVID-19) infection commonly presents with respiratory symptoms, but neurologic complications have been reported. A few studies have reported the occurrence of facial nerve palsy during the COVID-19 pandemic. Read More

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Acute non-traumatic tetraparesis - Differential diagnosis.

J Clin Neurosci 2021 May 20;87:116-124. Epub 2021 Mar 20.

Department of Neurology, Hospital da Luz Lisboa, Lisbon, Portugal; Department of Neurology, Department of Neurosciences and Mental Health, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon, Portugal; Institute of Physiology, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal.

Introduction: Potentially life-threatening disorders may present in the emergency department with acute tetraparesis, and their recognition is crucial for an appropriate management and timely treatment. Our review aims to systematize the differential diagnosis of acute non-traumatic tetraparesis.

Results: Causes of tetraparesis can be classified based on the site of defect: upper motor neuron (UMN), peripheral nerve, neuromuscular junction or muscle. Read More

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Artery of Percheron infarction: A case report and literature review.

Radiol Case Rep 2021 Jun 28;16(6):1271-1275. Epub 2021 Mar 28.

University Clinical Center, Clinic of Radiology, University for Business and Technology - Radiology.

The artery of Percheron (AOP) represents a rare anatomic variant of the posterior circulation. It is a solitary trunk that provides bilateral arterial supply to the rostral midbrain and paramedian thalamus. AOP infarction presentation varies, most often presents with altered mental status, memory impairment, and supranuclear vertical gaze palsy. Read More

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Intramedullary schwannoma of cervicomedullary junction: A case report.

Neurochirurgie 2021 Apr 9. Epub 2021 Apr 9.

Department of neurosurgery, Istanbul Medipol University, School of medicine, TEM Goztepe exit, Bagcilar/Istanbul, Turkey.

Background: Intramedullary schwannomas of brain stem and spinal cord are extremely rare. In almost all cases, homogeneous, asymmetrical or circular intensive gadolinium enhancement has been demonstrated. However, no cases reported previously with minimal contrast enhancement in cervicomedullary junction. Read More

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Acute Hemorrhagic Encephalitis Related to COVID-19.

Neurol Clin Pract 2021 Apr;11(2):e147-e151

Department of Clinical Neurological Sciences (AC, RBJ, CJ, DBD, DAS), Schulich School of Medicine and Dentistry, Western University; Department of Physical Medicine and Rehabilitation (CSB), Schulich School of Medicine and Dentistry, Western University; Department of Medical Imaging (MSM), Schulich School of Medicine and Dentistry, Western University; Department of Medicine (KJB), Schulich School of Medicine and Dentistry, Western University; and Department of Epidemiology and Biostatistics (DAS), Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.

Purpose Of Review: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the most critical public health challenge in recent history. In this report, we present a case of suspected acute hemorrhagic encephalitis with bilateral intracranial hemorrhages associated with coronavirus disease 2019 (COVID-19) infection.

Recent Findings: A 48-year-old female COVID-19-positive patient developed acute changes in her neurologic status. Read More

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A Case of Dapsone-induced Mild Methemoglobinemia with Dyspnea and Cyanosis.

Acta Dermatovenerol Croat 2020 Dec;28(4):249-250

Hisayoshi Imanishi, MD, PhD, Division of Dermatology, Daito Central Hospital, 2-1-11 Ono, Daito, Osaka 574-0042, Japan;

Dear Editor, Dapsone is a dual-function drug with antimicrobial and antiprotozoal effects and anti-inflammatory features (1). In dermatology, it is a first choice for conditions such as leprosy, IgA pemphigus, dermatitis herpetiformis, and linear IgA bullous dermatosis, or an adjunctive treatment for, e.g. Read More

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December 2020

A nontraumatic myositis ossificans case of the forearm: Case report and literature review.

Exp Ther Med 2021 May 23;21(5):531. Epub 2021 Mar 23.

Department of Physical and Rehabilitation Medicine, University of Medicine and Pharmacy of Craiova, Craiova 200349, Romania.

Myositis ossificans (MO) is a rare, benign ossifying lesion characterized by focal formation of heterotopic bone and cartilage in extraskeletal soft-tissue that most commonly occurs in young adults. In most cases, no causative factor can be identified. The diagnosis of MO is usually based on the patient's history of trauma, clinical signs, on imaging appearance and histological examination. Read More

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Altered peri-seizure EEG microstate dynamics in patients with absence epilepsy.

Seizure 2021 May 25;88:15-21. Epub 2021 Mar 25.

Department of Neurology, The Affiliated Hospital of Southwest Medical University, Luzhou, 646000, China; Laboratory of Neurological Diseases and Brain Function, Luzhou, 646000, China. Electronic address:

Objective: To investigate whether the parameters of EEG microstates changed before and after an absence seizure episode.

Methods: AE patients with a current high frequency of seizures were included (n=21). Each included subject underwent a two-hour and 19-channel video EEG examination. Read More

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Skull hemophilia pseudotumor: A case report.

Open Med (Wars) 2021 22;16(1):435-439. Epub 2021 Mar 22.

Department of Neurosurgery, Affiliated Fuzhou First Hospital of Fujian Medical University, No. 190, Dadao Road, Fuzhou 350009, Fujian, China.

Background: In this study, a rare case with hemophilia pseudotumor in the skull was reported.

Case Presentation: The case was a 34-year-old male patient who was admitted to the hospital, with the complaint of dizziness for more than 1 month. The physical examination indicated that the patient was conscious, who could give right answers to the questions. Read More

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Velamentous cord insertion, ischemic-hypoxic encephalopathy, and neurological rehabilitation: A case report

Biomedica 2021 03 19;41(1):8-16. Epub 2021 Mar 19.

Escuela de Ciencias de la Salud, Universidad Pontificia Bolivariana, Medellín, Colombia; Línea de Investigación en Discapacidad, Grupo de Investigación en Salud Pública, Facultad de Medicina, Universidad Pontificia Bolivariana, Medellín, Colombia.

Hypoxic-ischemic encephalopathy is a frequent and important cause of neurological problems in term and preterm newborns. A sentinel event of this entity is the vasa previa, specifically when there is an abnormality of the placenta such as a velamentous cord insertion. Some reports have shown the association between these two entities, but those regarding the recovery process and the neurological prognosis of children with both conditions are scarce. Read More

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New mutation in Fabry disease: c.448delG, first phenotypic description.

Mol Genet Metab Rep 2021 Jun 3;27:100708. Epub 2021 Mar 3.

Instituto de Estudios Inmunológicos y Fisiopatológicos (IIFP), UNLP, CONICET, asociado CIC PBA, Facultad de Ciencias Exactas, Departamento de Ciencias Biológicas, La Plata, Argentina.

Fabry disease (FD) (Anderson-Fabry disease, OMIM 301500) is a genetic disorder caused by a pathogenic variant in the GLA gene on chromosome Xq22 that produces a deficiency in the lysosomal enzyme alpha-galactosidase A. It is transmitted as an X-linked trait, although de novo mutations have been described. The objective of this report is to describe the clinical characteristics of a patient with FD who is a carrier of a mutation not previously studied, in order to provide information on the genotype-phenotype correlation in this pathology. Read More

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C1 Hemilaminectomy for Resection of Foramen Magnum Meningioma: 2-Dimensional Operative Video.

J Neurol Surg B Skull Base 2021 Feb 13;82(Suppl 1):S35-S36. Epub 2020 Mar 13.

Department of Neurological Surgery, Eberhard-Karls-University, University Hospital Tübingen, Tübingen, Germany.

We present a case of a sizeable foramen magnum meningioma that was resected through a C1 hemilaminectomy in prone (concorde) position. The patient is a 51-year-old woman with a 3-month history of progressive paresthesia of the upper and lower extremities, followed by gait disturbance, and hand apraxia. There was no complaint of nuchal pain. Read More

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February 2021

Patient Harm Due to Diagnostic Error of Neuro-Ophthalmologic Conditions.

Ophthalmology 2021 Mar 11. Epub 2021 Mar 11.

Department of Ophthalmology, Emory University, Atlanta, Georgia; Department of Neurology, Emory University, Atlanta, Georgia. Electronic address:

Purpose: To prospectively examine diagnostic error of neuro-ophthalmic conditions and resultant harm at multiple sites.

Design: Prospective, cross-sectional study.

Participants: A total of 496 consecutive adult new patients seen at 3 university-based neuro-ophthalmology clinics in the United States in 2019 to 2020. Read More

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A Multi-Method Approach to a Comprehensive Examination of the Psychiatric and Neurological Consequences of Intimate Partner Violence in Women: A Methodology Protocol.

Front Psychiatry 2021 19;12:569335. Epub 2021 Feb 19.

The Translational Research Center for Traumatic Brain Injury and Stress Disorders and the Geriatric Research, Education and Clinical Center, Veterans Affairs Boston Healthcare System, Boston, MA, United States.

The number of women in the United States that experience blows to the head during assaults by intimate partners is substantial. The number of head blows that result in a traumatic brain injury (TBI) is virtually unknown, but estimates far exceed numbers of TBI in parallel populations (e.g. Read More

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February 2021

Neurological examination course in an interactive webinar as a solution during a pandemic. An overview of the implementation, optimization as well as critical considerations.

GMS J Med Educ 2021;38(1):Doc9. Epub 2021 Jan 28.

Universitätsklinikum Essen, Klinik für Neurologie, Essen, Germany.

The COVID-19 pandemic made the traditional bedside teaching inaccessible for medical students. Within a short period of time, established bedside teaching concepts had to be converted into online formats to meet the requirements of the health authorities. The Department of Neurology at the University Hospital Essen transformed the examination course in the 5 clinical semester into a live stream, taking into account data protection guidelines. Read More

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