2,769 results match your criteria Neurological History and Physical Examination

Blastic plasmacytoid dendritic cell neoplasm and cerebral toxoplasmosis: a case report.

BMC Neurol 2022 Jun 24;22(1):233. Epub 2022 Jun 24.

Department of Neurology, Rigshospitalet Glostrup, Faculty of Health and Medical Sciences, University of Copenhagen, Glostrup, Denmark.

Background: The present case contributes to the limited literature on central nervous system involvement of blastic plasmacytoid dendritic cell neoplasm (BPDCN).  CASE PRESENTATION : A 63-year-old male presented to the department of neurology with a three-day history of rapidly progressing headache, fatigue, and confusion. Physical examination revealed multiple bruise-like skin lesions. Read More

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Letter to the Editor: Depression As The First Symptom Of Frontal Lobe Grade 2 Malignant Glioma.

Turk Psikiyatri Derg 2022 ;33(2):143-145

Dear Editor, Next to focal neurological symptoms, epileptic seizures and head aches, brain tumors can less frequently bring about cognitive changes, slowed speech, difficulty sustaining mental functioning and psychiatric symptoms of personality changes and. loss of interest in daily activities, these symptoms may be evaluated as anxiety or depression. Depression is known to be a complication of brain tumours and may sometimes be seen after the presentation of neurological symptoms linked to brain tumours, and sometimes after tumor treatment (Oğuz et al. Read More

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Mechanisms of Transcranial Doppler Ultrasound phenotypes in paediatric cerebral malaria remain elusive.

Malar J 2022 Jun 21;21(1):196. Epub 2022 Jun 21.

Dept of Osteopathic Medical Specialties, College of Osteopathic Medicine, Michigan State University, East Lansing, MI, 48824, USA.

Background: Cerebral malaria (CM) results in significant paediatric death and neurodisability in sub-Saharan Africa. Several different alterations to typical Transcranial Doppler Ultrasound (TCD) flow velocities and waveforms in CM have been described, but mechanistic contributors to these abnormalities are unknown. If identified, targeted, TCD-guided adjunctive therapy in CM may improve outcomes. Read More

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Neurological Waardenburg-Shah syndrome: a diagnostic challenge in a child with skin hypopigmentation and neurological manifestation.

BMJ Case Rep 2022 Jun 20;15(6). Epub 2022 Jun 20.

Department of Genetics, Kuala Lumpur General Hospital, Ministry of Health Malaysia, Kuala Lumpur, Wilayah Persekutuan, Malaysia.

Peripheral demyelinating neuropathy, central dysmyelinating leukodystrophy, Waardenburg syndrome and Hirschsprung disease (PCWH) is a rare manifestation of Waardenburg-Shah syndrome associated with mutations in the gene. The phenotypic expression is variable, thus presenting a diagnostic challenge. Clinical manifestations of PCWH may mimic other neurocutaneous syndromes. Read More

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Acute unilateral vestibulopathy/vestibular neuritis: Diagnostic criteria.

J Vestib Res 2022 Jun 11. Epub 2022 Jun 11.

Department of Otorhinolaryngology, Lund University, Lund, Sweden.

This paper describes the diagnostic criteria for Acute Unilateral Vestibulopathy (AUVP), synonymous for vestibular neuritis, as defined by the Committee for the Classification of Vestibular Disorders of the Bárány Society. AUVP manifests as an acute vestibular syndrome due to an acute unilateral loss of peripheral vestibular function without evidence for acute central or acute audiological symptoms or signs. This implies that the diagnosis of AUVP is based on the patient history, bedside examination, and, if necessary, laboratory evaluation. Read More

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Case series on the Charcot neuroarthropathy in hands after cervical central cord syndrome.

BMC Musculoskelet Disord 2022 Jun 6;23(1):545. Epub 2022 Jun 6.

Department of Rehabilitation Medicine, Beijing Haidian Hospital, Beijing, China.

Background: Charcot neuroarthropathy (CNA) of the upper extremity occurs most frequently in shoulders. However, CNA in the hands is uncommon and seldom be reported. The onset of CNA is usually insidious. Read More

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The Conundrum of Dystonia in Essential Tremor Patients: How does One Classify these Cases?

Tremor Other Hyperkinet Mov (N Y) 2022 13;12:15. Epub 2022 May 13.

Department of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Background: The relationship between essential tremor (ET) and dystonia has been long debated and the boundaries between these disorders remain unclear. Here, we highlight the diagnostic uncertainty that can arise when observing dystonic postures in patients who have received ET diagnoses.

Methods: An international panel of seven movement disorders neurologists from five countries reviewed the clinical history and videotaped neurological examinations of five individuals diagnosed with ET who also had various features of dystonia on neurological examination. Read More

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Pontine stroke: a rare mimicker of Bell's palsy.

Med J Malaysia 2022 05;77(3):403-405

Taiping Hospital, Department of Internal Medicine, Taiping, Perak, Malaysia.

Pontine infarct is a rare but clinically significant cause of an isolated facial nerve palsy. Prompt diagnosis with the use of magnetic resonance imaging (MRI) allows early initiation of treatment for such patients. We report a 62-year-old gentleman with diabetes, hypertension, and gout, presenting with lower motor neuron facial nerve palsy. Read More

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Diagnosis and management of Henoch-Schonlein purpura in Indonesian elderly with severe complication: A rare case.

Ann Med Surg (Lond) 2022 May 20;77:103650. Epub 2022 Apr 20.

Department of Internal Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.

Background: Henoch-Schonlein purpura (HSP) in the elderly is very rare, so this case report was conducted to improve the diagnosis and management of HSP.

Case Presentation: A 65-year-old Indonesian male with severe complications of HSP had been reported. In addition to the patient's history, physical examination, laboratory and radiological findings, he performed a left sole anterior biopsy that showed interstitial infiltrate of main neutrophils, and faint granular deposits of IgA and C3 seen within the superficial vessels. Read More

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Contralateral Recurrence of a Lumbar Juxtafacet Cyst Following Spontaneous Resolution.

J Coll Physicians Surg Pak 2022 Apr;32(4):S85-S88

School of Medicine, Adiyaman University, Adiyaman, Turkey.

We present a patient who had spontaneous resolution of a right L3/4 lumbar juxtafacet cyst (LJFC); and in whom, 2.5 years after regression of the previous cyst, a new contralateral L3/4 LJFC developed. Furthermore, with an extensive review, we discuss the selection criteria for patients for conservative treatment. Read More

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Clinical Significance and Value of Serum Homocysteine and Urine 11 Dehydrothromboxane B2 Combined with Transferrin-Specific Peptide in the Diagnosis of Cerebral Apoplexy.

Comput Math Methods Med 2022 17;2022:6130413. Epub 2022 May 17.

Hubei No. 3 People's Hospital of Jianghan University, Clinical Laboratory, 430033, China.

Objective: To explore the clinical significance and value of serum homocysteine (Hcy) and urine 11 dehydrothromboxane B2 (urine 11-DH-TXB2) combined with transferrin-specific peptide (TF-UP) in the diagnosis of stroke.

Methods: One hundred stroke patients treated from January 2019 to June 2021 were enrolled in our hospital as the study group. All the patients in the study group met the diagnostic criteria of stroke. Read More

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[The Greek-Roman physician Galen of Pergamum and his neurological case histories].

Werner Golder

Nervenarzt 2022 May 23. Epub 2022 May 23.

, 23 rue de l'Oriflamme, 84000, Avignon, Frankreich.

Background: The case histories in the writings of Galen of Pergamum have so far been interpreted primarily in literary and socio-historic terms. The analysis focused on the medical aspects is still incomplete.

Question: Which neurological competences do the galenic case reports communicate?

Material And Methods: The 400 galenic case histories were studied for anamnestic, clinical, therapeutic, and prognostic statements on neurological and psychiatric diseases. Read More

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Thoracic Spinal Cord Compression Secondary to Metastatic Papillary Thyroid Carcinoma: An Unusual Oncological Phenomenon.

Cureus 2022 Apr 17;14(4):e24206. Epub 2022 Apr 17.

Pathology, AMITA Health Saint Francis Hospital, Evanston, USA.

Hematogenous spread is fairly an unusual feature for papillary thyroid carcinoma (PTC) in comparison to follicular thyroid carcinoma (FTC). Thoracic spinal metastasis with complicating cord compression is an even rarer manifestation of PTC that was reported in a limited number of cases in the literature. Herein we present a 65-year-old female with a history of PTC on current radiotherapy, status post attempted surgery due to significant tumor burden and intraoperative bleeding, presented with a one-week history of rapidly progressive bilateral lower extremities weakness. Read More

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[Functional Movement Disorders That Do Not Improve after Explaining the Diagnosis: The Role of Neurologists].

Brain Nerve 2022 May;74(5):559-564

Department of Neurology, Hirosaki University Graduate School of Medicine.

In recent years, the term "functional" is starting to replace "psychogenic" when referring to a specific group of movement disorders, with an increasing emphasis being placed on the role of neurologists in the management of these disorders. These conditions are common and disabling, and sometimes difficult to diagnose. History taking and physical examination may highlight positive signs suggestive of diagnosis, which should not be based on exclusion. Read More

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Does ultrasound imaging of the spastic muscle have an additive effect on clinical examination tools in patients with cerebral palsy?: A pilot study.

North Clin Istanb 2022 11;9(2):102-108. Epub 2022 Mar 11.

Department of Physical Medicine and Rehabilitation, Marmara University School of Medicine, Istanbul, Turkey.

Objective: The Modified Ashworth Scale, the Modified Tardieu Scale, and measuring the passive range of motion is commonly preferred examination tools for spasticity in cerebral palsy (CP). Ultrasonography has become increasingly used to provide relevant insight into spastic muscle morphology and structure recently. It was aimed to reveal associations between the clinical and ultrasonographic parameters of gastrocnemius medialis (GM) and lateralis muscles in this population. Read More

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Hypsarrhythmia paroxysm intensities that initiate and render physical and mental retardation irreversible in West syndrome.

Int J Neurosci 2022 May 24:1-9. Epub 2022 May 24.

SANKARA Brain and Biotechnology Research Center, Technology Development Zone, Istanbul University, Fatih, Turkey.

Purpose: The present study would like to investigate the effect of hypsarrhythmia paroxysms on neurological examination findings.

Material And Method: This study enrolled 48 children with normal cranial magnetic resonance imaging (cMRI) findings who were previously untreated with adrenocorticotropic hormone (ACTH) and had no history of asphyxia or anoxia at birth, no underlying disease, and no history of head trauma or central nervous system infection. In these children, duration of treatment delay (DTD) was calculated, HPs in NREM sleep were counted, and neurological examination findings were identified. Read More

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EEG Oscillatory Networks in Peri-Ictal Period of Absence Epilepsy.

Front Neurol 2022 25;13:825225. Epub 2022 Apr 25.

Department of Neurology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.

Objective: To investigate the dynamical brain network changes before and after an absence seizure episode in absence epilepsy (AE).

Methods: 21 AE patients with a current high frequency of seizures and 21 sex- and age-matched health control (HC) who reported no history of neurological or psychiatric disorders and visited the hospital for routine physical examinations were included. Each included subject underwent a 2-h and 19-channel video EEG examination. Read More

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Using Single-Photon Emission Computerized Tomography on Patients With Positive Quantitative Electroencephalogram to Evaluate Chronic Mild Traumatic Brain Injury With Persistent Symptoms.

Front Neurol 2022 11;13:704844. Epub 2022 Apr 11.

Faculty of Medicine, University of Toronto, Toronto, ON, Canada.

Background: Following mild traumatic brain injury (mTBI), also known as concussion, many patients with chronic symptoms (>3 months post injury) receive conventional imaging such as computed tomography (CT) or magnetic resonance imaging (MRI). However, these modalities often do not show changes after mTBI. We studied the benefit of triaging patients with ongoing symptoms >3 months post injury by quantitative electroencephalography (qEEG) and then completing a brain single positron emission computed tomography (SPECT) to aid in diagnosis and early detection of brain changes. Read More

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Successful Treatment of Ureteral Obstructive Lithiasis by Ureterotomy in a Domestic Hen.

J Avian Med Surg 2022 May;36(1):70-77

Division of Diagnostic Imaging, Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, 3584 CM Utrecht, The Netherlands.

A 2-year-old domestic hen was presented for a 15-day history of intermittent left leg lameness. The owners also observed a decrease in egg quality during that period. Physical examination of the bird revealed a generalized weakness with a flattened pale comb. Read More

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Assessing floppy infants: a new module.

Eur J Pediatr 2022 Jul 4;181(7):2771-2778. Epub 2022 May 4.

Centro Clinico Nemo Pediatrico, Fondazione Policlinico "A. Gemelli" IRCCS, Rome, Italy.

Our aim was to develop a new module for assessing the floppy infant, to describe the application of the module in a cohort of low-risk newborns and piloting the module in a cohort of floppy infants. The module was applied to a cohort of 143 low-risk newborns and piloted in in a cohort of 24 floppy infants. The new add-on module includes a neurological section and provides a section for recording information obtained by physical examination and antenatal history. Read More

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Ned Tijdschr Geneeskd 2022 03 3;166. Epub 2022 Mar 3.

Radboudumc, Nijmegen: Afd. Eerstelijnsgeneeskunde, Centrum voor Huisartsgeneeskunde-Ouderengeneeskunde en Public Health.

In old age, cognitive functions decline in comparison to performance earlier in life. Subjective memory complaints often cause anxiety. Patient and informant history taking, along with simple additional cognitive tests are usually sufficient to reassure patients or to initiate further diagnostic work-up. Read More

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Essential thrombocythemia with CALR mutation and recurrent stroke: two case reports and literature review.

Ther Adv Neurol Disord 2022 26;15:17562864221092093. Epub 2022 Apr 26.

Department of Neurology, Xijing Hospital, Air Force Medical University, 127 Changle West Road, Xi'an 710032, Shaanxi Province, China.

Cerebrovascular events, especially ischemic stroke, are common complications of essential thrombocythemia (ET). Compared to JAK2V617 F mutation, CALR mutation is considered as a lower risk factor of thrombosis in ET. Until now stroke in ET with CALR mutation has rarely been reported. Read More

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Gastric cancer complicated by paraneoplastic neurological syndrome which presented with extremity numbness: a case report.

Surg Case Rep 2022 Apr 28;8(1):78. Epub 2022 Apr 28.

Department of Gastroenterological Surgery 1, Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-ku, Sapporo, 060-8638, Japan.

Background: Paraneoplastic neurological syndromes refer to a group of neurological disorders, which occur as distant effects of malignant tumors and are not caused by metastasis, nutritional disorders, or side effects of antitumor drugs.

Case Presentation: A 70-year-old woman complained of a 1-month history of extremity numbness. Upon presentation to our hospital, she had worsening numbness, and experienced staggering and falling. Read More

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Coxofemoral luxation as a complication of localised tetanus in a cat.

JFMS Open Rep 2022 Jan-Jun;8(1):20551169221090889. Epub 2022 Apr 19.

Department of Veterinary Neurology and Neurosurgery, The Koret School of Veterinary Medicine, Rehovot, Israel.

Case Summary: A 9-month-old male neutered domestic shorthair cat presented 2 weeks after castration with a 48 h history of acute-onset lateral recumbency and severe hindlimb rigidity. Physical examination findings included hyperthermia, tachypnoea, hindlimb rigidity and a healed orchidectomy site. Neurological examination of the head and forelimbs was normal; however, there was a spastic, non-ambulatory paraparesis of the hindlimbs, which was more severe on the left. Read More

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Diagnosis of Functional Weakness and Functional Gait Disorders in Children and Adolescents.

Semin Pediatr Neurol 2022 04 11;41:100955. Epub 2022 Mar 11.

Department of Neurosciences, Queensland Childrens Hospital, Brisbane, Queensland, Australia; The University of Queensland, Brisbane, Queensland, Australia. Electronic address:

Functional neurological disorder is neurological dysfunction not primarily explained by pathophysiologic or structural abnormalities and can present in children and adolescents with limb weakness, gait abnormality, non-epileptic seizures or sensory changes. In this review article we focus primarily on the diagnosis of functional limb weakness and functional gait disorders, and how to differentiate functional neurological disorders from structural or pathologic neurological presentations of weakness or gait disturbance. Detailed history and attentive observation of a patient outside of the formal neurological examination can be pertinent to identifying inconsistency and incongruency in keeping with functional neurological presentations. Read More

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A Study for Evaluation of Altered Mental Status Patients in Medicine Department.

J Assoc Physicians India 2022 Apr;70(4):11-12

Sms Medical College and Attached Hospital, Jaipur, Rajasthan.

Altered mental status (AMS) comprises a group of clinical symptoms rather than a specific diagnosis, and includes cognitive disorders, attention disorders, arousal disorders, and decreased level of consciousness. Patients often manifest vague symptoms, thus, AMS diagnosis and treatment are highly challenging for general medicine physicians.

Material: This was an observational cross-sectional analytical study. Read More

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Prevalence and Risk Factors for Unruptured Intracranial Aneurysms in the Population at High Risk for Aneurysm in the Rural Areas of Tianjin.

Front Neurol 2022 23;13:853054. Epub 2022 Mar 23.

Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China.

Although the prevalence of unruptured intracranial aneurysm (UIA) lies between 2 and 5%, the consequences of aneurysm rupture are fatal. The burden of UIA is considerable in stroke patients. However, the best prevention and management strategy for UIA is uncertain among patients with a family history of stroke. Read More

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Connectomic profiling and Vagus nerve stimulation Outcomes Study (CONNECTiVOS): a prospective observational protocol to identify biomarkers of seizure response in children and youth.

BMJ Open 2022 04 8;12(4):e055886. Epub 2022 Apr 8.

Division of Neurosurgery, Hospital for Sick Children, Department of Neurosurgery, University of Toronto, Toronto, Ontario, Canada

Introduction: Vagus nerve stimulation (VNS) is a neuromodulation therapy that can reduce the seizure burden of children with medically intractable epilepsy. Despite the widespread use of VNS to treat epilepsy, there are currently no means to preoperatively identify patients who will benefit from treatment. The objective of the present study is to determine clinical and neural network-based correlates of treatment outcome to better identify candidates for VNS therapy. Read More

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Tool Use for Early Detection of Cerebral Palsy: A Survey of Spanish Pediatric Physical Therapists.

Pediatr Phys Ther 2022 04;34(2):202-210

Faculty of Physical Therapy and Nursing (Mr Merino-Andrés and Dr Pérez-Nombela), University of Castilla-La Mancha, Toledo Physical Therapy Research Group, Toledo, Spain; Toledo Physical Therapy Research Group (GIFTO) (Messrs Merino-Andrés and Dr Pérez-Nombela), University of Castilla-La Mancha, Toledo, Spain; Centro Crecer (Mr Merino-Andrés), Toledo, Spain; Faculty of Education (Mr Hidalgo-Robles), Universidad Internacional de La Rioja, La Rioja, Spain; Curtin School of Allied Health (Dr Williams), Curtin University, Perth, Western Australia; Liggins Institute (Dr Williams), The University of Auckland, Auckland, New Zealand; Montgomery County Infants and Toddlers Program (Dr Paleg), Rockville, Maryland; Department of Physical Therapy (Dr Fernández-Rego) and Early Intervention Research Group (GIAT) (Dr Fernández-Rego), University of Murcia, Murcia, Spain.

Purpose: The purpose of this study was to assess the use of diagnostic assessment tools in pediatric physical therapy practice in Spain. Best practice recommendations indicate the timely use of key assessment tools to reduce the age of diagnosis of cerebral palsy (CP).

Methods: Pediatric physical therapists currently working in Spain in early intervention were recruited through targeted physical therapy entities. Read More

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