299 results match your criteria Neuroimaging in Neurocysticercosis

Recurrent Neurocysticercosis: Not So Rare.

Neurol India 2021 Mar-Apr;69(2):385-391

Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.

Background: Solitary cysticercus granuloma (SCG) appearing as a single ring-enhancing lesion (SREL) is the most frequently encountered imaging finding in patients of neurocysticercosis (NCC) in India and during follow-up, most of SCGs resolve with or without calcifications. Recurrent SCG have been rarely reported.

Objectives: The aim of our study is to report the incidence of recurrent SCG in a cohort of patients with SCG and postulate the hypothesis. Read More

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Neurocysticercosis Presenting With a New-Onset Seizure: A Case Report.

Cureus 2021 Mar 15;13(3):e13897. Epub 2021 Mar 15.

Internal Medicine/Infectious Disease, Richmond University Medical Center, Staten Island, USA.

Neurocysticercosis (NCC) is a common infection that is found worldwide but is often neglected in the United States (US). This case report aims to illustrate the presentation of the disease, provide information on this globally prevalent pathogen, and shed light on the diagnostic workup and treatment of the infection. We discuss the case of a 31-year-old male patient of Central American origin presenting with a new-onset seizure. Read More

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High frequency of Taenia solium antigen positivity in patients admitted for neurological disorders in the Rural Hospital of Mosango, Democratic Republic of Congo.

BMC Infect Dis 2021 Apr 17;21(1):359. Epub 2021 Apr 17.

Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.

Background: The epidemiology of human cysticercosis and neurocysticercosis, caused by the larval stage of the pork tapeworm Taenia solium, is not well known in the Democratic Republic of Congo (DRC). Within a multicenter etiological and diagnostic study conducted by the NIDIAG consortium ("Better Diagnosis for Neglected Infections") and investigating several challenging syndromes, we consecutively evaluated from 2012 to 2015 all patients older than 5 years presenting with neurological disorders (neurology cohort) and with fever > 7 days (persistent fever cohort) at the rural hospital of Mosango, province of Kwilu, DRC. In both cohorts, etiological diagnosis relied on a systematic set of reference laboratory assays and on pre-established clinical case definitions. Read More

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[Clinical characteristics of neurocysticercosis from a reference hospital of the northern of Peru. 2016-2018].

Rev Chilena Infectol 2020 Dec;37(6):690-693

Hospital Regional Lambayeque, Perú.

Backgound: Neurocysticercosis (NCC) is the most common parasitosis of the central nervous system, and a very important cause of epilepsy.

Aim: To describe the clinical features of patients with NCC attending a high level hospital from Lambayeque during: 2016-2018.

Methods: The medical records of patients with NCC were reviewed, and their information was collected on a data sheet. Read More

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December 2020

Neurocysticercosis in patients with active epilepsy in the tea garden community of Assam, Northeast India.

Sci Rep 2021 Apr 1;11(1):7433. Epub 2021 Apr 1.

ICMR-Regional Medical Research Centre, N. E. Region, Dibrugarh, Assam, 786001, India.

Neurocysticercosis is a significant cause of epilepsy in the tropics. The present cross-sectional survey was conducted in the socioeconomically backward tea garden community of Assam to gauge the prevalence of neurocysticercosis in patients with active epilepsy and to determine the associated risk factors. In a door to door survey, a total of 1028 individuals from every fifth household of the study Teagarden were enrolled to identify self-reported seizure cases, followed by a neurological examination to confirm the diagnosis of active epilepsy. Read More

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The effectiveness of anti-inflammatory and anti-seizure medication for individuals with single enhancing lesion neurocysticercosis: A meta-analysis and expert group-based consensus recommendations.

PLoS Negl Trop Dis 2021 Mar 31;15(3):e0009193. Epub 2021 Mar 31.

Department of Neurology, Center for Global Health, School of Medicine, Technical University of Munich, Munich, Germany.

Single brain enhancing lesions (SEL) are the most common presentation of neurocysticercosis (NCC) observed on neuroimaging in people presenting with epileptic seizures not only on the Indian sub-continent and in travelers returning from cysticercosis-endemic regions, but are also present in other parts of the world. The aim of this study, which consisted of a systematic review (CRD42019087665), a meta-analysis and an expert group consultation, was to reach consensus on the best anti-seizure medication and anti-inflammatory treatment for individuals with SEL NCC. Standard literature review methods were used. Read More

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Nightmares with a starry sky - Treating neurocysticercal encephalitis, how far to go.

Trop Parasitol 2020 Jul-Dec;10(2):158-162. Epub 2021 Jan 25.

Department of Neuro-Ophthalmology, Institute of Neurosciences, Kolkata, West Bengal, India.

Cysticercosis, an infection caused by the larval stage of tapeworm , is the most common parasitic disease of the human nervous system and the single most common cause of acquired epileptic seizures in the developing world. Here, we describe the stormy course of a 67-year-old female with neurocysticercosis (NCC) having a recurrent encephalitic presentation. She went through the most severe spectrum of this disease, namely NCC encephalitis and disseminated cysticercosis and had a classical starry sky brain in neuroimaging. Read More

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January 2021

Neuroradiology of infectious diseases.

Curr Opin Infect Dis 2021 Jun;34(3):228-237

Section of Infectious Diseases, UT Health McGovern Medical School, Houston, Texas, USA.

Purpose Of Review: Early diagnosis of central nervous system (CNS) infections is crucial given high morbidity and mortality. Neuroimaging in CNS infections is widely used to aid in the diagnosis, treatment and to assess the response to antibiotic and neurosurgical interventions.

Recent Findings: The Infectious Diseases Society of America (IDSA) guidelines have clear recommendations for obtaining a computerized tomography of the head (CTH) prior to lumbar puncture (LP) in suspected meningitis. Read More

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Neurocysticercosis and movement disorders: A literature review.

Brain Circ 2020 Oct-Dec;6(4):225-241. Epub 2020 Dec 29.

Department of Medicine, Federal University of Fronteira Sul, Passo Fundo, RS, Brazil.

Neurocysticercosis (NCC) is a specific form of cysticercosis that affects the central nervous system. It is caused by the tapeworm , which is often found in pigs. NCC is considered one of the "great simulator/mimickers" of other diseases. Read More

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December 2020

Surgical management of cerebral peduncle neurocysticercosis: A case report of decision making in a resource-restricted environment.

Int J Surg Case Rep 2021 Jan 4;78:26-29. Epub 2020 Dec 4.

Department of Neurosurgery I, Viet Duc University Hospital, Hanoi, Viet Nam. Electronic address:

Background: Diagnosis and treatment of neurocysticercosis have always been a challenge, especially in Vietnam, a resource-restricted environment. Here, we reported successful surgical management of cerebral peduncle neurocysticercosis.

Presentation Of Case: A 65-year-old man with no medical history complained of headache and progressive right-sided hemiparesis for one month prior to admission. Read More

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January 2021

Dual/double pathology in neurocysticercosis causing drug resistant epilepsy - Chance association or causal?

Epilepsy Res 2020 12 22;168:106472. Epub 2020 Sep 22.

Department of Neuropathology, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India. Electronic address:

Introduction: Neurocysticercosis (NCC) as cause of drug resistant epilepsy (DRE) is commonly reported from India. We reviewed the neuropathological findings in patients undergoing resective surgery for DRE due to NCC, to determine the pathomechanism of epileptogenesis.

Methods: Clinical, demographic and neuropathological findings of histologically confirmed cases of NCC causing DRE between 2005-2019 were reviewed. Read More

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December 2020

"Malignant" Craniospinal Neurocysticercosis: A Rare Case.

World Neurosurg 2021 Feb 27;146:95-102. Epub 2020 Oct 27.

Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India.

Background: Neurocysticercosis (NCC) is the commonest parasitic infection of the central nervous system. There is significant difference in incidence of NCC depending on geographic location, and incidence as high as 4% is reported in the endemic areas. It results from human affliction by the larval stage of Taenia solium. Read More

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February 2021

Endoscopic intervention for intraventricular neurocysticercal cyst: Challenges and outcome analysis from a single institute experience.

Clin Neurol Neurosurg 2020 Nov 2;198:106179. Epub 2020 Sep 2.

Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bengaluru, India. Electronic address:

Objective: Endoscopic intervention is presently proposed as standard approach for the treatment of Intraventricular neurocysticercal cyst (IVNCC) as it helps to retrieve the cyst as well as CSF diversion. We present our series of 61 patients with IVNCC managed by endoscopic intervention and analyze the outcome.

Method: A retrospective analysis of 61 patients with IVNCC managed between 1998-2019 at our institute was performed. Read More

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November 2020

Identification of Taenia solium DNA by PCR in blood and urine samples from a tertiary care center in North India.

J Neurol Sci 2020 Oct 29;417:117057. Epub 2020 Jul 29.

Department of Medical Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India. Electronic address:

Background: NCC is a neglected zoonotic disease with high endemicity and disease burden. Neurocysticercosis is a frequent cause of seizures in endemic countries. Early diagnosis and therapy helps in reducing morbidity and DALYs (daily adjusted life years) lost. Read More

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October 2020

Multiple neurocysticercosis and aneurismal subarachnoid hemorrhage: case presentation and systematic literature review.

Infez Med 2020 Jun;28(2):268-272

Universidad Señor de Sipán, Chiclayo, Lambayeque, Peru; Department of Internal Medicine, Hospital Regional Lambayeque, Chiclayo, Peru.

Neurocysticercosis (NCC) is a global health problem. In more developed countries, NCC is mainly a disease affecting immigrants. In developing countries, NCC is the most common parasitic disease of the nervous system and the main cause of acquired epilepsy. Read More

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Egg yolk immunoglobulin Y as a promising tool to detect immune complexes in neurocysticercosis serum samples.

Trans R Soc Trop Med Hyg 2020 08;114(8):585-592

Laboratório de Diagnóstico de Parasitoses, Instituto de Ciências Biomédicas, Universidade Federal de Uberlândia, Av. Pará, 1720, Uberlândia, Minas Gerais, 38400-902, Brazil.

Background: Neurocysticercosis (NCC) is a neglected tropical disease and its diagnosis is still a challenge due to non-specific manifestations. Neuroimaging techniques are used in the diagnosis of NCC, however, due to the high cost of these methods and the advantages presented in the use of immunological tests, such as ease of performance and satisfactory results, immunoassays are commonly used to detect antibodies against Taenia sp. antigens. Read More

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Taenia solium Cysticercosis and Its Impact in Neurological Disease.

Clin Microbiol Rev 2020 06 27;33(3). Epub 2020 May 27.

Department of International Health, Johns Hopkins School of Public Health, Baltimore, Maryland, USA.

neurocysticercosis (NCC) is endemic in most of the world and contributes significantly to the burden of epilepsy and other neurological morbidity. Also present in developed countries because of immigration and travel, NCC is one of few diseases targeted for eradication. This paper reviews all aspects of its life cycle (taeniasis, porcine cysticercosis, human cysticercosis), with a focus on recent advances in its diagnosis, management, and control. Read More

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Next-generation sequencing of cerebrospinal fluid for the diagnosis of neurocysticercosis.

Clin Neurol Neurosurg 2020 06 26;193:105752. Epub 2020 Feb 26.

Department of Neurology, Xijing Hospital, The Fourth Military Medical University, 15 Changle xi Road, Xi'an, 710032, China. Electronic address:

Objective: Neurocysticercosis (NCC) is the most common parasitic disease of the human central nervous system (CNS). However, a diagnosis of NCC may be hard to make if the specific clinical and routine neuroimaging manifestations are lacking, which hinders physicians from considering further immunodiagnostic tests.

Patients And Methods: Seven patients presented with fever, headache, nausea, cognitive decline, confusion, or progressive leg weakness. Read More

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Saudi J Kidney Dis Transpl 2020 Jan-Feb;31(1):254-258

Department of Pharmacy Practice, Deccan School of Pharmacy, Hyderabad, Telangana, India.

Neurocysticercosis (NCC) is one of the common parasitic central nervous system (CNS) infections. Improperly cooked pork and eggs of the tapeworm Taenia solium, entering the body through the feco-oral route, are the common sources of its infection. Affected person may remain asymptomatic for long periods and can present with a variety of neurological manifestations, including focal neurological deficits and generalized seizures. Read More

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January 2021

Brain MRI Findings in Coenurosis: A Helminth Infection.

J Neuroimaging 2020 05 18;30(3):359-369. Epub 2020 Feb 18.

Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, India, (RM, BNN).

Background And Purpose: Parasitic neuroinfections in humans have etiological agents spanning a broad spectrum from unicellular (protozoan) to multicellular helminthic (metazoan) organisms. Cerebral coenurosis is a rare cestodal helminthic infection caused by Taenia multiceps. The neuroimaging features of this entity were reviewed to discern an imaging phenotype. Read More

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A Case Report of Intraparenchymal Neurocysticercosis in a Postpartum Female in Saudi Arabia.

Saudi J Med Med Sci 2020 Jan-Apr;8(1):60-63. Epub 2019 Dec 23.

Department of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Neurocysticercosis is a neurologic disease caused by infection with larvae of . It is most commonly transmitted by consumption of pork, water contaminated with or poor hygiene habits. As only few cases of neurocysticercosis have been documented in Saudi Arabia, the authors report a case of neurocysticercosis in a young Indian female residing in Saudi Arabia who presented with generalized tonic-clonic seizures 6 days after a normal vaginal delivery. Read More

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December 2019

Twenty-five years of evolution of standard diagnostic criteria for neurocysticercosis. How have they impacted diagnosis and patient outcomes?

Expert Rev Neurother 2020 02 25;20(2):147-155. Epub 2019 Dec 25.

School of Medicine, Universidad Espíritu Santo - Ecuador, Samborondón, Ecuador.

: Neurocysticercosis (NCC) is the most common helminthic infection of the central nervous system and a global public health problem. However, its diagnosis is complicated since histological demonstration of the parasite is often not feasible, clinical manifestations are nonspecific, most neuroimaging findings are not pathognomonic, and immunological tests have problems related to poor reliability. Unified chart of criteria is needed to standardize the diagnosis of NCC in different settings. Read More

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February 2020

Atypical radiological presentation of multiple cystic brain metastases from lung cancer simulating neurocysticercosis.

BMJ Case Rep 2019 Oct 5;12(10). Epub 2019 Oct 5.

Department of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University, Chieti, Italy

Brain metastases (BMs) are usually characterised by vasogenic oedema and mass effect, but cystic appearance can rarely occur, mimicking parasitosis, such as neurocysticercosis (NCC). A woman in her mid-50s was admitted for dizziness and upper left extremity paresis. Neuroimaging showed multiple cystic lesions consistent with multiple stages of NCC evolution, and empiric albendazole was started, without any clinical improvement. Read More

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October 2019

Value of Multimodal Imaging Approach to Diagnosis of Neurosarcoidosis.

Brain Sci 2019 Sep 21;9(10). Epub 2019 Sep 21.

Institute of Neurology, Magna Græcia University, 88100 Catanzaro, Italy.

Background: Neurosarcoidosis is a highly variable condition with many clinical and radiological manifestations, that can lead to difficult identification of isolated central nervous system (CNS) forms, because it could mimic inflammatory, infective or neoplastic disorders. Conventional magnetic resonance imaging (MRI) is gold standard to evaluate CNS involvement in neurosarcoidosis, despite the reported high sensitivity but low specificity in the diagnosis.

Case Presentation: Here, we describe a 52-year-old man that presented to our hospital with a 10-year history of focal seizures, progressive cognitive decline and motor impairment. Read More

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September 2019

A longitudinal analysis of albendazole treatment effect on neurocysticercosis cyst evolution using multistate models.

Trans R Soc Trop Med Hyg 2019 12;113(12):781-788

Department of Epidemiology and Biostatistics, CUNY Graduate School of Public Health and Health Policy, City University of New York, 55 West 125th Street, New York, New York 10027, USA.

Background: In neurocysticercosis, the larval form of the pork tapeworm Taenia solium appears to evolve through three phases-active, degenerative and sometimes calcification-before disappearance. The antihelmintic drug, albendazole, has been shown to hasten the resolution of active cysts in neurocysticercosis. Little is known about the time cysts take to progress through each phase, with or without treatment. Read More

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December 2019

Subarachnoid neurocysticercosis and an intracranial infectious aneurysm: case report.

Neurosurg Focus 2019 08;47(2):E16

Infectious intracranial aneurysms (IIAs) represent 2%-6% of all intracranial aneurysms and, classically, have been associated with bacterial or fungal agents. The authors report the case of a 42-year-old woman who presented with a typical history of subarachnoid hemorrhage. Digital subtraction angiography (DSA) showed an aneurysmal dilatation on the frontal M2 segment of the left middle cerebral artery (MCA). Read More

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A Large Cohort of Neurocysticercosis in Shandong Province, Eastern China, 1997-2015.

Vector Borne Zoonotic Dis 2019 12 17;19(12):901-907. Epub 2019 Jul 17.

World Health Organization Collaborating Centre for Lymphatic Filariasis and Taeniasis/Cysticercosis, Shandong Institute of Parasitic Diseases, Shandong First Medical University & Shandong Academy of Medical Sciences, Jining, Shandong Province, China.

Neurocysticercosis (NCC) has a wide spectrum of neurologic and psychiatric manifestations, including epileptic seizures, high intracranial pressure, cognitive dysfunction, and meningoencephalitis. This study presents the clinical diagnosis of 2539 NCC patients in Shandong Province, Eastern China, from 1997 to 2015. The diagnosis was based primarily on clinical features, neuroimaging, immunology, and electroencephalogramy studies. Read More

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December 2019

3D-Double-Inversion recovery detects perilesional gliosis better than 3D-FLAIR and postcontrast T1 imaging in calcified neurocysticercosis.

Neurol India 2019 Jan-Feb;67(1):136-141

Department of Radiology and Imaging, Fortis Memorial Research Institute, Gurugram, Haryana, India.

Background: Perilesional gliosis is an important substrate for seizures in patients harboring a calcified neurocysticercosis (NCC) lesion and magnetic resonance imaging (MRI) is useful for evaluating gliosis.

Aims: The purpose of this study was to evaluate the usefulness of double-inversion recovery (DIR) sequence for identifying perilesional gliosis.

Settings And Design: Hospital-based cross-sectional study. Read More

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December 2019

Three-dimensional double inversion recovery magnetic resonance sequence detects perilesional gliosis better than 3D-FLAIR and postcontrast T1 imaging in calcified neurocysticercosis.

Neurol India 2019 Jan-Feb;67(1):74-75

Department of Radiology, University Hospitals, Birmingham NHS Foundation Trust; Department of Radiology, University of Birmingham, Birmingham, UK.

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February 2020

Structural Equation Modeling (SEM) of Cysticercosis in School-Aged Children in Tibetan Rural Farming Areas of Western China: Implications for Intervention Planning.

Int J Environ Res Public Health 2019 03 4;16(5). Epub 2019 Mar 4.

Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA 94305, USA.

Neurocysticercosis (NCC) significantly contributes to morbidity in developing countries. We recently published a study of prevalence and risk factors in school-aged children in three mountainous areas in Sichuan province of western China. Using structural equation modeling (SEM) on data from that study to guide intervention planning, here we examine risk factors grouped into three broad interventional categories: sociodemographics, human behavior, and sources of pork and pig husbandry. Read More

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