268 results match your criteria Neuroimaging in Neurocysticercosis


3D-Double-Inversion recovery detects perilesional gliosis better than 3D-FLAIR and postcontrast T1 imaging in calcified neurocysticercosis.

Neurol India 2019 Jan-Feb;67(1):136-141

Department of Radiology and Imaging, Fortis Memorial Research Institute, Gurugram, Haryana, India.

Background: Perilesional gliosis is an important substrate for seizures in patients harboring a calcified neurocysticercosis (NCC) lesion and magnetic resonance imaging (MRI) is useful for evaluating gliosis.

Aims: The purpose of this study was to evaluate the usefulness of double-inversion recovery (DIR) sequence for identifying perilesional gliosis.

Settings And Design: Hospital-based cross-sectional study. Read More

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http://dx.doi.org/10.4103/0028-3886.253614DOI Listing
March 2019
1 Read

Structural Equation Modeling (SEM) of Cysticercosis in School-Aged Children in Tibetan Rural Farming Areas of Western China: Implications for Intervention Planning.

Int J Environ Res Public Health 2019 Mar 4;16(5). Epub 2019 Mar 4.

Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA 94305, USA.

Neurocysticercosis (NCC) significantly contributes to morbidity in developing countries. We recently published a study of prevalence and risk factors in school-aged children in three mountainous areas in Sichuan province of western China. Using structural equation modeling (SEM) on data from that study to guide intervention planning, here we examine risk factors grouped into three broad interventional categories: sociodemographics, human behavior, and sources of pork and pig husbandry. Read More

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http://dx.doi.org/10.3390/ijerph16050780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427563PMC
March 2019
1 Read

Conglomerate Ring-Enhancing Lesions are Common in Solitary Neurocysticercosis and do not always Suggest Neurotuberculosis.

Ann Indian Acad Neurol 2019 Jan-Mar;22(1):67-72

Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.

Background And Purpose: Differentiating between neurocysticercosis (NCC) and neurotuberculosis has serious therapeutic implications and this distinction relies heavily on neuroimaging. Few case reports discuss the conglomeration of ring-enhancing lesions (RELs) in patients with solitary NCC. The aim of our study is to describe the imaging findings of conglomerate RELs in a cohort of patients with solitary NCC, emphasizing the frequency of conglomeration. Read More

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http://dx.doi.org/10.4103/aian.AIAN_221_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327694PMC
January 2019
6 Reads

Comparison of complementary diagnostic tests in cerebrospinal fluid and serum for neurocysticercosis.

Heliyon 2018 Dec 1;4(12):e00991. Epub 2018 Dec 1.

Instituto de Investigación en Salud Pública y Zoonosis, Facultad de Medicina Veterinaria y Zootecnia, Universidad Central del Ecuador, Quito, Ecuador.

The role of immunologic tests in the diagnosis of neurocysticercosis (NC) is controversial and few studies have made comparisons among them. The objective of this study was to compare immunological tests in both serum and cerebrospinal fluid (CSF) for the diagnosis of NC. We conducted a case-control study in Cuenca, Ecuador, enrolling patients with NC (N = 24) and matching them with other neurosurgical patients (N = 18). Read More

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http://dx.doi.org/10.1016/j.heliyon.2018.e00991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278713PMC
December 2018
2 Reads

Overview of Taenia solium cysticercosis in West Africa.

Acta Trop 2019 Feb 7;190:329-338. Epub 2018 Dec 7.

Bristol Veterinary School, University of Bristol, Langford, Bristol, BS40 5DU, United Kingdom; School of Biological Sciences, Queen's University Belfast, 97, Lisburn Road, Belfast, BT9 7BL, United Kingdom.

Human and porcine cysticercosis is endemic in West Africa, where epilepsy is relatively common, but rarely reported due to fear of stigmatization. Neurocysticercosis, caused by Taenia solium, tends to affect the poor in developing countries and control is hampered by inadequate infrastructure and financial resources coupled with lack of adequate information about its significance and distribution. The risk factors for human cysticercosis are closely associated with the characteristics of smallholder or backyard pig farming systems prevalent in this region. Read More

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http://dx.doi.org/10.1016/j.actatropica.2018.12.012DOI Listing
February 2019
3 Reads

Detection of DNA in the Urine of Neurocysticercosis Patients.

Am J Trop Med Hyg 2019 Feb;100(2):327-329

W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.

Neurocysticercosis (NCC), caused by larvae that reside in the central nervous system, results in serious public health and medical issues in many regions of the world. Current diagnosis of NCC is complex requiring both serology and costly neuroimaging of parasitic cysts in the brain. This diagnostic pipeline can be problematic in resource-constrained settings. Read More

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http://dx.doi.org/10.4269/ajtmh.18-0706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367601PMC
February 2019
8 Reads

Neurocysticercosis: a reversible and rare cause of seizure in the developed world.

BMJ Case Rep 2018 Oct 30;2018. Epub 2018 Oct 30.

Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1136/bcr-2018-227479DOI Listing
October 2018
5 Reads

Perfusion magnetic resonance imaging in differentiation of neurocysticercosis and tuberculoma.

Neuroradiology 2019 Mar 30;61(3):257-263. Epub 2018 Oct 30.

Department of Pediatrics, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Purpose: Tuberculoma and neurocysticercosis (NCC) are two of the most common intracranial infections in developing countries and cause of seizures or focal neurological deficit. They often present on neuroimaging as ring-enhancing lesions, and in absence of typical imaging features, can cause significant diagnostic dilemma. Differentiation is extremely important to avoid empirical exposure to anti-tubercular treatment or nonspecific treatment causing disease progression. Read More

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http://link.springer.com/10.1007/s00234-018-2118-x
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http://dx.doi.org/10.1007/s00234-018-2118-xDOI Listing
March 2019
21 Reads
2.485 Impact Factor

Updates on the management of neurocysticercosis.

Curr Opin Infect Dis 2018 10;31(5):377-382

Center for Global Health, Universidad Peruana Cayetano Heredia.

Purpose Of Review: The goal of this review is highlight recent developments regarding neurocysticercosis, including recently developed guidelines.

Recent Findings: Recent diagnostic criteria highlight the importance of neuroimaging in establishing a diagnosis. Monoclonal antibody-based antigen detection and the enzyme-linked immunotransfer blot can be confirmatory. Read More

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http://Insights.ovid.com/crossref?an=00001432-900000000-9925
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http://dx.doi.org/10.1097/QCO.0000000000000480DOI Listing
October 2018
12 Reads

Clinical topography relationship in patients with parenchymal neurocysticercosis and seizures.

Epilepsy Res 2018 09 28;145:145-152. Epub 2018 Jun 28.

Center for Global Health - Tumbes, Universidad Peruana Cayetano Heredia, Lima, Peru; Cysticercosis Unit, Department of Transmissible Diseases, Instituto Nacional de Ciencias Neurologicas, Lima, Peru; Department of Microbiology, School of Sciences, Universidad Peruana Cayetano Heredia, Lima, Peru.

Objective: Discordances between imaging findings of parenchymal neurocysticercosis and seizure expression have been reported, and as such the possibility that neurocysticercosis and seizures may frequently coexist by chance has been raised. In this study, we evaluate the topographic relationship between seizure foci based on semiology and electroencephalography with the location of parenchymal neurocysticercotic lesions.

Methods: Seizure information, neuroimaging (computed tomography and magnetic resonance imaging [MRI]) and electroencephalographic data from three randomized clinical trials of individuals with parenchymal neurocysticercosis and focal seizures were analyzed. Read More

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http://dx.doi.org/10.1016/j.eplepsyres.2018.06.011DOI Listing
September 2018
11 Reads

Next-Generation Sequencing of Cerebrospinal Fluid for the Diagnosis of Neurocysticercosis.

Front Neurol 2018 19;9:471. Epub 2018 Jun 19.

Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Neurocysticercosis (NCC) is the most common helminthic infection of the central nervous system (CNS). The diagnosis of NCC is sometimes challenging due to its heterogenous clinical manifestations and the variable sensitivity and specificity of neuroimaging and serological tests. Next-generation sequencing (NGS) of cerebrospinal fluid (CSF) was used to detect pathogens in patients with clinically suspected CNS infections. Read More

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http://dx.doi.org/10.3389/fneur.2018.00471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018529PMC
June 2018
15 Reads

Neurocysticercosis in Children with Seizures: A Cross-Sectional Study.

Int J Pediatr 2018 21;2018:1030878. Epub 2018 May 21.

Department of Pediatrics, Universal College of Medical Sciences, Bhairahawa 32900, Nepal.

Background: Neurocysticercosis (NCC), a common cause of seizures in children from low and middle income countries (LMICs), if not diagnosed and treated early enough may lead to considerable morbidity and mortality. There is a lack of data on the prevalence of NCC and its clinical characteristics among those with seizure in South-Western Nepal.

Aims And Objectives: To study the prevalence and clinical characteristics of NCC in children with seizures. Read More

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http://dx.doi.org/10.1155/2018/1030878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987327PMC
May 2018
26 Reads

Solitary Brain Mass in a Patient with Seizures: An Unexpected Infectious Etiology.

Diseases 2018 Jun 22;6(3). Epub 2018 Jun 22.

Division of Infectious Diseases, Department of Medicine, Huntsville Hospital, Huntsville, AL 35801, USA.

Neurocysticercosis is a parasitosis caused by the larval stage of the pork tapeworm The diagnosis is challenging as morphology on neuroimaging can be inconclusive and serology is frequently negative. We describe the case of a 24-year old Hispanic man who presented with seizures and loss of consciousness. Magnetic resonance imaging (MRI) showed a cystic mass in right frontal lobe. Read More

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http://dx.doi.org/10.3390/diseases6030054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163356PMC
June 2018
5 Reads

The Many Faces of Neurocysticercosis.

J Neurol Sci 2018 07 12;390:75-76. Epub 2018 Apr 12.

Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address:

Neurocysticercosis (NCC) is the most common parasitic disease of the central nervous system, and one of the most common causes of epilepsy worldwide. The radiologic appearance of neurocysticercosis varies depending on the stage of the disease, and the stage of the disease determines the appropriate treatment. In this article, we review key neuroimaging characteristics of the stages of NCC (vesicular, colloidal, granular, and calcified) and treatment principles for these different stages of the disease. Read More

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http://dx.doi.org/10.1016/j.jns.2018.04.018DOI Listing
July 2018
2 Reads

Role of Immuno-Polymerase Chain Reaction (I-PCR) in Resolving Diagnostic Dilemma Between Tuberculoma and Neurocysticercosis: A Case Report.

Am J Case Rep 2018 May 24;19:599-603. Epub 2018 May 24.

Centre for Biotechnology, Maharshi Dayanand University (MDU), Rohtak, Haryana, India.

BACKGROUND Tuberculoma and neurocysticercosis (NCC) often show similar clinical and neuroimaging features. Differential diagnosis of these 2 diseases is imperative, as tuberculoma is an active infection that requires immediate anti-tubercular therapy (ATT). CASE REPORT We present the case of a 17-year-old Indian girl with fever, severe headache, and right 6th cranial nerve palsy. Read More

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http://dx.doi.org/10.12659/AJCR.908624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994961PMC
May 2018
7 Reads

Atypical presentation of posterior reversible encephalopathy syndrome: Two cases.

J Anaesthesiol Clin Pharmacol 2018 Jan-Mar;34(1):120-122

Department of Anaesthesiology, Lady Hardinge Medical College and Smt. SSK Hospital, New Delhi, India.

Posterior reversible encephalopathy syndrome (PRES) is a clinico-neuroradiological entity, first described in 1996. It is commonly associated with systemic hypertension, intake of immunosuppressant drugs, sepsis and eclampsia and preeclampsia. Headache, alteration in consciousness, visual disturbances and seizures are common manifestations of PRES. Read More

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http://dx.doi.org/10.4103/0970-9185.173351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885427PMC
April 2018
6 Reads

Neurocysticercosis: the good, the bad, and the missing.

Expert Rev Neurother 2018 04 14;18(4):289-301. Epub 2018 Mar 14.

f Departamento de Medicina , Universidade de Taubaté , São Paulo , Brazil.

Introduction: Neurocysticercosis (NC) is a neglected disease that contributes substantially to neurological morbidity/mortality in lower-income countries and increasingly among high-income countries due to migration. Many advances have been made in understanding NC, but unanswered questions remain Areas covered: This review discusses the epidemiology, pathophysiology, immunology, diagnosis, treatment, and eradication of NC. Expert commentary: The global NC prevalence remains unknown and needs proper ascertainment. Read More

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http://dx.doi.org/10.1080/14737175.2018.1451328DOI Listing
April 2018
8 Reads

Seroprevalence of human cysticercosis in Jataí, Goiás state, Brazil.

Braz J Infect Dis 2018 Mar - Apr;22(2):146-149. Epub 2018 Feb 10.

Universidade Federal de Goiás, Laboratório de Imunologia, Jataí, GO, Brazil. Electronic address:

The Taenia solium cysticercosis affects millions of people worldwide and is considered a public health problem, especially in developing countries. The diagnosis of neurocysticercosis is complex and involves the analysis of epidemiological, clinical, neuroimaging, and immunological host data. Neurocysticercosis is endemic in Brazil, and is related to the cause of death mainly in the Southeast, South, and Central-West regions. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14138670173085
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http://dx.doi.org/10.1016/j.bjid.2018.01.002DOI Listing
July 2018
16 Reads

Giant Intraparanchymal Neurocysticercosis.

J Assoc Physicians India 2017 Nov;65(11):85-86

Post graduates in General Medicine, Govt. Mohan Kumaramangalam Medical College Hospital, Salem, Tamil Nadu.

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November 2017
11 Reads

Neuroimaging of Dilated Perivascular Spaces: From Benign and Pathologic Causes to Mimics.

J Neuroimaging 2018 Mar 27;28(2):139-149. Epub 2017 Dec 27.

Department of Radiology, Division of Neuroradiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

Perivascular spaces (PVSs), also known as Virchow-Robin spaces, are pial-lined, fluid-filled structures found in characteristic locations throughout the brain. They can become abnormally enlarged or dilated and in rare cases can cause hydrocephalus. Dilated PVSs can pose a diagnostic dilemma for radiologists because of their varied appearance, sometimes mimicking more serious entities such as cystic neoplasms, including dysembryoplastic neuroepithelial tumor and multinodular and vacuolating neuronal tumor, or cystic infections including toxoplasmosis and neurocysticercosis. Read More

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http://doi.wiley.com/10.1111/jon.12493
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http://dx.doi.org/10.1111/jon.12493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398334PMC
March 2018
17 Reads

Spontaneously Arrested Transmission of Cysticercosis in a Highly Endemic Village with a Very Low Migration Rate.

Am J Trop Med Hyg 2018 03 14;98(3):776-778. Epub 2017 Dec 14.

Cysticercosis Unit, Instituto Nacional de Ciencias Neurológicas, Lima, Perú.

cysticercosis is difficult to eliminate without interventions or societal development. Atahualpa is a rural Ecuadorian village with documented low migration rate, where domestic pig raising is common and human cysticercosis is endemic. To assess neurocysticercosis (NCC) prevalence, 1,273 villagers aged ≥ 20 years underwent neuroimaging studies, which showed calcified lesions in 121 (9. Read More

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http://dx.doi.org/10.4269/ajtmh.17-0723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930905PMC
March 2018
14 Reads

MicroRNAs in Neurocysticercosis: Insights as Promising Agents in Host-Parasite Interaction and Their Potential as Biomarkers.

Front Microbiol 2017 29;8:1905. Epub 2017 Sep 29.

Neurocysticercosis Lab, Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Peru.

MicroRNAs (miRNAs) are short, endogenous, non-coding, single-stranded RNAs involved in post-transcriptional gene regulation. Although, several miRNAs have been identified in parasitic helminths, there is little information about their identification and function in . Furthermore, the impact of miRNAs in neurocysticercosis, the brain infection caused by larvae of is still unknown. Read More

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http://journal.frontiersin.org/article/10.3389/fmicb.2017.01
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http://dx.doi.org/10.3389/fmicb.2017.01905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626859PMC
September 2017
6 Reads
1 Citation
3.941 Impact Factor

Fourth ventricle neurocysticercosis: Rigid endoscopic management. Description of direct transcerebellar approach.

Surg Neurol Int 2017 26;8:232. Epub 2017 Sep 26.

Neurosurgery Department, Centro Médico "Lic. Adolfo López Mateos", Instituto de Salud del Estado de México, Av. Nicolas San Juan s/n Ex Hacienda La Magdalena, Estado de México, México.

Background: Endoscopy has gained a crucial role in high specialty neurosurgery during the last decades. At present, there are well-defined flexible neuroendoscopic procedures to treat ventricular and subarachnoid space pathologies. Neurocysticercosis is recognized as a common cause of neurologic disease in developing countries and the United States. Read More

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http://dx.doi.org/10.4103/sni.sni_251_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629842PMC
September 2017
31 Reads

Clinical and neuroimaging predictors of seizure recurrence in solitary calcified neurocysticercosis: A prospective observational study.

Epilepsy Res 2017 11 20;137:78-83. Epub 2017 Sep 20.

Department of Radiology and Imaging, Fortis Memorial Research Institute, Gurgaon, India.

Background: Solitary calcified neurocysticercosis is a common cause of seizures in the developing countries. Factors responsible for seizure recurrence in patients with solitary calcified neurocysticercosis are not known. We evaluated the clinical, neuroimaging and biochemical predictors of seizure recurrence. Read More

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http://dx.doi.org/10.1016/j.eplepsyres.2017.09.010DOI Listing
November 2017
43 Reads

Pediatric Neurocysticercosis.

Indian J Pediatr 2019 Jan 20;86(1):76-82. Epub 2017 Sep 20.

Pediatric Neurology and Neurodevelopment Unit, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Neurocysticercosis is the most common helminth infection of nervous system in humans caused by the encysted larvae of Taenia solium. It is a major cause of epilepsy in tropical areas and the most common cause of focal-onset seizures in North Indian children. Children with neurocysticercosis have pleomorphic manifestations depending on the location, number and viability of the cysts and host response. Read More

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http://dx.doi.org/10.1007/s12098-017-2460-8DOI Listing
January 2019
8 Reads

Head CT findings at a public hospital in rural Haiti.

J Neurol Sci 2017 Aug 20;379:327-330. Epub 2017 Jun 20.

Harvard Medical School, Boston, MA, USA; Hôpital Universitaire de Mirebalais, Partners In Health, Haiti; Department of Neurology, Brigham and Women's Hospital, USA. Electronic address:

Background: Neuroimaging is often unavailable in low-income countries, creating challenges for precise diagnosis of neurologic disease in individual patients, and impeding acquisition of precise neuroepidemiologic data for program and policy development.

Methods: We analyzed reports from 3614 head CTs performed between July 2013 and January 2016 at Hôpital Universitaire de Mirebalais, a public academic hospital in rural Haiti, extracting patients' age, study indication, and radiologic findings.

Results: The most common indications for head CT were headache (27%), trauma (19. Read More

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http://dx.doi.org/10.1016/j.jns.2017.06.029DOI Listing
August 2017
9 Reads

Computerized Axial Tomography Findings in Children with Afebrile Seizures: A Hospital Based Study at Eastern Nepal.

J Nepal Health Res Counc 2017 Jan;15(35):61-66

Department of Pediatrics and Adolescent Medicine, B.P. Koirala Institute of Health Sciences, Sunsari, Nepal.

Background: Computerized Tomography can be performed in resource limited areas where Magnetic Resonance Imaging is less practical. This study was conducted to find out the proportion of cases with abnormal CT scan and findings of CT scan in children with afebrile seizures in a resource limited area.

Methods: This prospective study was conducted from 1st July 2009 to 31st March 2014 in a university hospital of Nepal. Read More

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January 2017
3 Reads

Parkinsonism and other movement disorders in 23 cases of neurocysticercosis.

Parkinsonism Relat Disord 2017 Sep 20;42:47-53. Epub 2017 Jun 20.

Neurology Department, Hospital Eugenio Espejo, Quito, Ecuador; SENESCYT, Ecuador; CIBERNED, Spain; Carlos III Health Institute, Madrid, Spain.

Introduction: Parkinsonism and other movement disorders have been occasionally described in neurocysticercosis (NCC) but their clinical features and pathogenesis are not well understood.

Methods: This is a descriptive study conducted over 20 years. We studied 590 consecutive patients from the NCC Registry at Eugenio Espejo Hospital, Quito, Ecuador, and found 23 subjects who developed movement disorders. Read More

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http://dx.doi.org/10.1016/j.parkreldis.2017.06.009DOI Listing
September 2017
7 Reads

[An underestimated cause of seizure in Europe].

Rev Med Suisse 2017 Jun;13(567):1263-1265

Service d'accueil des urgences, Hôpitaux universitaires de Strasbourg, Hôpital de Hautepierre, avenue Molière 1, 67098 Strasbourg, France.

Seizures are very common in the Emergency Department (ED). We present here a case of a young woman with neurocysticercosis ; a worldwide and nearly endemic cause of seizure in the southern hemisphere. Clinical manifestations are very different between patients from asymptomatic to life-threatening hydrocephalus. Read More

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June 2017
14 Reads

Intracranial Infectious and Inflammatory Diseases Presenting as Neurosurgical Pathologies.

Neurosurgery 2017 Jul;81(1):10-28

Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia.

There are many infectious and inflammatory processes affecting the central nervous system that can simulate other neurosurgical pathologies (e.g. tumor) and may precipitate a brain biopsy for definitive diagnosis if not suspected a priori. Read More

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https://academic.oup.com/neurosurgery/article-lookup/doi/10.
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http://dx.doi.org/10.1093/neuros/nyx201DOI Listing
July 2017
14 Reads

[Racemose neurocysticercosis: Neuroimaging guides the diagnosis].

Biomedica 2017 Apr 1;37(0):26-32. Epub 2017 Apr 1.

Sección de Neurología, Departamento de Medicina Interna, Hospital Universitario de San Vicente Fundación, Universidad de Antioquia, Medellín, Colombia.

Neurocysticercosis is the leading cause of parasitosis of the central nervous system and acquired epilepsy in developing countries. The clinical manifestations of neurocysticercosis, especially its racemose variant, are pleomorphic and unspecific, characteristics that hinder the diagnosis and make it a challenge for the clinician.The objective of this report was to describe two cases of racemose neurocysticercosis in which neuroimaging led to the definitive diagnosis. Read More

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http://dx.doi.org/10.7705/biomedica.v37i2.2983DOI Listing
April 2017
32 Reads

Solitary Cysticercal Cyst Inside the Blake's Pouch Remnant of Mega Cisterna Magna with Associated Aqueductal Stenosis: Clinical and Management Implications.

World Neurosurg 2017 Jun 19;102:693.e1-693.e5. Epub 2017 Apr 19.

Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

Background: Intraventricular and subarachnoid forms represent the relatively complex, albeit uncommon, manifestations of central nervous system involvement by cysticercal cysts. Cysticercal encystation inside the Blake's pouch remnant of mega cisterna magna (MCM) remains an extremely rare clinical scenario that, to the best of our knowledge, has not been reported previously.

Case Presentation: A 12-year-old boy presented with acute worsening and subsequent spontaneous resolution of his compensated hydrocephalus. Read More

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http://dx.doi.org/10.1016/j.wneu.2017.04.067DOI Listing
June 2017
19 Reads

T2 relaxometry helps prognosticate seizure outcome in patients with solitary cerebral cysticercosis.

J Neurol Sci 2017 May 27;376:1-6. Epub 2017 Feb 27.

Department of Biostatistics, National Institute of Mental Health and NeuroSciences, Bangalore 560 029, India.

Objective: Correlate serial T2 relaxometry (T2R) values with long term seizure outcome in patients with solitary cerebral cysticercosis (SCC) in order to establish its usefulness as a prognostic marker in these patients.

Methods: Patients with new-onset seizures due to SCC were imaged serially using a pre-determined MRI protocol at enrolment and after 3, 6, 12 and 24months. T2 relaxometry was performed using a dual echo sequence with maps generated manually from the measured image intensities at the level of the lesion. Read More

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http://dx.doi.org/10.1016/j.jns.2017.02.052DOI Listing

The causal relationship between neurocysticercosis infection and the development of epilepsy - a systematic review.

Infect Dis Poverty 2017 Apr 5;6(1):31. Epub 2017 Apr 5.

Division of Infection and Pathway Medicine, Edinburgh Infectious Diseases, Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, Scotland, UK.

Background: Neurocysticercosis (NCC) is a parasitic infection of the human central nervous system, the most common form of which involves infection of the brain parenchyma with the larval form of the Taenia solium tapeworm. A causal relationship between such an NCC infection and the development of epilepsy in infected individuals is acknowledged, in part supported by high levels of comorbidity in endemic countries worldwide.

Methods: This study undertook a systematic review and critical analysis of the NCC-epilepsy relationship with the primary objective of quantifying the risk of developing epilepsy following NCC infection. Read More

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http://dx.doi.org/10.1186/s40249-017-0245-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381143PMC
April 2017
3 Reads

Disseminated neurocysticercosis presenting as acute stress reaction.

Ind Psychiatry J 2016 Jan-Jun;25(1):110-112

Department of Psychiatry, University College of Medical Sciences and Guru Teg Bahadur Hospital, Dilshad Garden, New Delhi, India.

Neurocysticercosis is the most common and preventable parasitic infection of the central nervous system, but disseminated cysticercosis is said to be rare. We report a case of a 31-year-old male, who presented with anxiety manifestations temporally associated with stress related to job. After initial clinical improvement, he presented with an incapacitating headache which was diagnosed as disseminated neurocysticercosis after thorough evaluation and investigations. Read More

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http://dx.doi.org/10.4103/0972-6748.196047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248410PMC
February 2017
2 Reads

Neurocysticercosis: Diagnostic problems & current therapeutic strategies.

Indian J Med Res 2016 Sep;144(3):319-326

Department of Neurological Sciences, Christian Medical College & Hospital, Vellore, India.

Neurocysticercosis (NCC) is the most common single cause of seizures/epilepsy in India and several other endemic countries throughout the world. It is also the most common parasitic disease of the brain caused by the cestode Taenia solium or pork tapeworm. The diagnosis of NCC and the tapeworm carrier (taeniasis) can be relatively inaccessible and expensive for most of the patients. Read More

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http://dx.doi.org/10.4103/0971-5916.198686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320837PMC
September 2016
5 Reads

Validity of a PCR assay in CSF for the diagnosis of neurocysticercosis.

Neurol Neuroimmunol Neuroinflamm 2017 Mar 16;4(2):e324. Epub 2017 Jan 16.

Facultad de Ciencias Médicas (A. Carpio, A. Campoverde, L.G., L.M.P.), Universidad de Cuenca, Ecuador; GH Sergievsky Center (A. Carpio), College of Physicians and Surgeons, Columbia University; Department of Epidemiology and Biostatistics (M.L.R.), CUNY Graduate School of Public Health and Health Policy, City University of New York, NY; Hospital del Instituto Ecuatoriano de Seguridad Social (L.M.P., N.L.), José Carrasco Arteaga; Hospital Vicente Corral Moscoso (M.P., J.A.), Ministerio de Salud Pública; Hospital Santa Inés (S.L.); Clínica Santa Ana (L.C.V.); and Hospital Universitario del Río (A.M.T., P.P.-T.), Cuenca, Ecuador.

Objective: To prospectively evaluate the validity of a PCR assay in CSF for the diagnosis of neurocysticercosis (NC).

Methods: We conducted a multicenter, prospective case-control study, recruiting participants from 5 hospitals in Cuenca, Ecuador, from January 2015 to February 2016. Cases fulfilled validated diagnostic criteria for NC. Read More

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http://dx.doi.org/10.1212/NXI.0000000000000324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241005PMC
March 2017
16 Reads

The Association Between Neurocysticercosis and Hippocampal Atrophy is Related to Age.

Am J Trop Med Hyg 2017 Jan 14;96(1):243-248. Epub 2016 Nov 14.

Center for Global Health, Tumbes, Perú.

Neurocysticercosis (NCC) has been associated with hippocampal atrophy, but the prevalence and pathogenic mechanisms implicated in this relationship are unknown. Using a population-based, case-control study design, residents in a rural village (Atahualpa) aged ≥ 40 years with calcified NCC were identified as cases and paired to NCC-free individuals (control subjects) matched by age, sex, and level of education. Cases and control subjects underwent magnetic resonance imaging for hippocampal rating according to the Scheltens' scale for medial temporal atrophy and were interviewed to identify those with a clinical seizure disorder. Read More

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http://dx.doi.org/10.4269/ajtmh.16-0689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239702PMC
January 2017
26 Reads

Long-term Clinical and Radiologic Outcome in 500 Children With Parenchymal Neurocysticercosis.

Pediatr Infect Dis J 2017 06;36(6):549-555

From the *Department of Pediatrics, †Unit of Pediatric Neurology and Neurodevelopment, Department of Pediatrics, and ‡Department of radio diagnosis and imaging, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Background: Our aim was to study long-term clinical and radiologic outcome in children with parenchymal neurocysticercosis (NCC) and its predictors.

Method: Five hundred children with NCC registered in the pediatric NCC clinic between January 1996 and December 2002 and followed till December 2009 were enrolled. Demographic details, clinical presentations and therapy received were recorded. Read More

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http://dx.doi.org/10.1097/INF.0000000000001536DOI Listing
June 2017
18 Reads

Revised diagnostic criteria for neurocysticercosis.

J Neurol Sci 2017 Jan 21;372:202-210. Epub 2016 Nov 21.

Center for Global Health, Tumbes, Peru; Department of Microbiology, School of Sciences, Universidad Peruana Cayetano Heredia, Peru; Cysticercosis Unit, Instituto Nacional de Ciencias Neurológicas, Lima, Peru. Electronic address:

Background: A unified set of criteria for neurocysticercosis (NCC) has helped to standardize its diagnosis in different settings.

Methods: Cysticercosis experts were convened to update current diagnostic criteria for NCC according to two principles: neuroimaging studies are essential for diagnosis, and all other information provides indirect evidence favoring the diagnosis. Recent diagnostic advances were incorporated to this revised set. Read More

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http://dx.doi.org/10.1016/j.jns.2016.11.045DOI Listing
January 2017
29 Reads

Revised set of diagnostic criteria for neurocysticercosis (in reply to Garg and Malhotra).

J Neurol Sci 2017 Feb 14;373:350-351. Epub 2016 Dec 14.

Center for Global Health, Tumbes and the Department of Microbiology, School of Sciences, Universidad Peruana Cayetano Heredia, Peru; Cysticercosis Unit, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.

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http://dx.doi.org/10.1016/j.jns.2016.12.018DOI Listing
February 2017
2 Reads

Association between Taenia solium infection and HIV/AIDS in northern Tanzania: a matched cross sectional-study.

Infect Dis Poverty 2016 Dec 1;5(1):111. Epub 2016 Dec 1.

Department of Neurology, University Hospital, Klinikum rechts der Isar, Technical University Munich (TUM), Ismaninger Str. 22, 81675, Munich, Germany.

Background: The frequency of Taenia solium, a zoonotic helminth, is increasing in many countries of sub-Saharan Africa, where the prevalence of the human immunodeficiency virus (HIV) is also high. However, little is known about how these two infections interact. The aim of this study was to compare the proportion of HIV positive (+) and negative (-) individuals who are infected with Taenia solium (TSOL) and who present with clinical and neurological manifestations of cysticercosis (CC). Read More

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http://dx.doi.org/10.1186/s40249-016-0209-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131417PMC
December 2016
23 Reads

Neurocysticercosis in Bhutan: a cross-sectional study in people with epilepsy.

Trans R Soc Trop Med Hyg 2016 09;110(9):517-526

Massachusetts General Hospital, Boston, MA, USA

Background: We sought to provide an assessment of the burden of neurocysticercosis among people with epilepsy (PWE) in Bhutan and evaluate the yield of various tests for Taenia solium.

Methods: PWE were enrolled at the National Referral Hospital in Thimphu (2014-2015). Serum was tested for anti-Taenia solium IgG using ELISA (Ab-ELISA), enzyme-linked immunoelectrotransfer blot (EITB), and parasite antigen. Read More

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http://dx.doi.org/10.1093/trstmh/trw066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444516PMC
September 2016
15 Reads

Update on the Diagnosis and Management of Neurocysticercosis.

Curr Infect Dis Rep 2016 Dec;18(12):44

Infectious Disease Division, Department of Internal Medicine, University of Texas Medical Branch, 301 University Boulevard, Rt 0435, Galveston, TX, 77555-0435, USA.

Neurocysticercosis is an important cause of seizures worldwide and is endemic in most of Latin America, Sub-Saharan Africa, Southeast Asia, India, and China. Neurocysticercosis has profoundly different disease manifestations varying from asymptomatic presentation to life-threatening hydrocephalus. Clinical manifestations, pathogenesis, diagnostic methods, and optimal treatment vary with the location, number of lesions, and host response. Read More

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http://dx.doi.org/10.1007/s11908-016-0547-4DOI Listing
December 2016
8 Reads

Imaging for Adults With Seizures and Epilepsy.

Continuum (Minneap Minn) 2016 Oct;22(5, Neuroimaging):1451-1479

Purpose Of Review: This article discusses structural and functional neuroimaging findings in patients with seizures and epilepsy. The indications for neuroimaging in these patients and the potential diagnostic utility of these studies are presented.

Recent Findings: Patients presenting with new seizures typically require urgent imaging to rule out a critical underlying cause. Read More

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http://dx.doi.org/10.1212/CON.0000000000000370DOI Listing
October 2016
6 Reads

Imaging Features of Neurocysticercosis: Analysis of 57 Consecutive Patients.

Turk Neurosurg 2017 ;27(3):386-394

Sichuan University, West China Hospital, Department of Neurosurgery, Chengdu, China.

Aim: To investigate the imaging features of neurocysticercosis and to provide valuable information about the diagnosis and treatment for clinicians.

Material And Methods: The data of 71 consecutive cases of neurocysticercosis, diagnosed by computed tomography (CT) and magnetic resonance imaging (MRI) between January 2009 and January 2014 in our institute were collected. Of all the cases, 57 patients met the recognized diagnostic criteria of neurocysticercosis. Read More

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http://dx.doi.org/10.5137/1019-5149.JTN.16209-15.0DOI Listing
December 2017
17 Reads

Predictors of Lesion Calcification in Patients with Solitary Cysticercus Granuloma and New-Onset Seizures.

Am J Trop Med Hyg 2016 09 18;95(3):623-8. Epub 2016 Jul 18.

Department of Neurology, King George Medical University, Uttar Pradesh, Lucknow, India.

Solitary cysticercus granuloma is a common neuroimaging abnormality in Indian patients with new-onset epilepsy. Calcific transformation of cysticercus granuloma is frequently associated with seizure recurrence. We evaluated predictors of lesion calcification in patients with solitary cysticercus granuloma and new-onset seizures. Read More

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http://dx.doi.org/10.4269/ajtmh.16-0070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5014269PMC
September 2016
16 Reads

Neurocysticercosis, familial cerebral cavernomas and intracranial calcifications: differential diagnosis for adequate management.

Arq Neuropsiquiatr 2016 Jun;74(6):495-500

Universidade Federal do Rio de Janeiro, Universidade Federal do Rio de Janeiro, Departamento de Neurocirurgia, Rio de Janeiro RJ , Brazil, Universidade Federal do Rio de Janeiro, Departamento de Neurocirurgia, Rio de Janeiro RJ, Brazil;

Neurocysticercosis (NCC) is an endemic disease and important public health problem in some areas of the World and epilepsy is the most common neurological manifestation. Multiple intracranial lesions, commonly calcified, are seen on cranial computed tomography (CT) in the chronic phase of the disease and considered one of the diagnostic criteria of the diagnosis. Magnetic resonance imaging (MRI) is the test that better depicts the different stages of the intracranial cysts but does not show clearly calcified lesions. Read More

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http://dx.doi.org/10.1590/0004-282X20160054DOI Listing
June 2016
9 Reads

Pulmonary neuroendocrine carcinoma mimicking neurocysticercosis: a case report.

J Med Case Rep 2016 Jun 2;10(1):144. Epub 2016 Jun 2.

Department of Medicine, The University of Calgary, Calgary, AB, T2N 2T9, Canada.

Background: Neurocysticercosis occurs when the eggs of the pork tapeworm (Taenia solium) migrate and hatch into larvae within the central nervous system. Neurocysticercosis is the most common cause of seizures in the developing world and is characterized on brain imaging by cysts in different stages of evolution. In Canada, cases of neurocysticercosis are rare and most of these patients acquire the disease outside of Canada. Read More

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http://dx.doi.org/10.1186/s13256-016-0910-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890325PMC
June 2016
20 Reads

Antiepileptic drug therapy and recommendations for withdrawal in patients with seizures and epilepsy due to neurocysticercosis.

Expert Rev Neurother 2016 09 8;16(9):1079-85. Epub 2016 Jun 8.

c School of Medicine , Universidad Espíritu Santo - Ecuador , Guayaquil , Ecuador.

Introduction: Neurocysticercosis (NCC) is a leading causes of secondary epilepsy worldwide. There is increasing evidence on the epileptogenic role of NCC, and the presence of edema, calcified scars, gliosis and hippocampal sclerosis support this phenomenon.

Areas Covered: We summarized principles of antiepileptic drug (AED) therapy as well as risk factors associated with seizure recurrence after AED withdrawal in patients with NCC. Read More

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http://dx.doi.org/10.1080/14737175.2016.1194757DOI Listing
September 2016
10 Reads