280 results match your criteria Neuroimaging in Neurocysticercosis


Taenia solium Cysticercosis and Its Impact in Neurological Disease.

Clin Microbiol Rev 2020 Jun 27;33(3). Epub 2020 May 27.

Department of International Health, Johns Hopkins School of Public Health, Baltimore, Maryland, USA.

SUMMARY neurocysticercosis (NCC) is endemic in most of the world and contributes significantly to the burden of epilepsy and other neurological morbidity. Also present in developed countries because of immigration and travel, NCC is one of few diseases targeted for eradication. This paper reviews all aspects of its life cycle (taeniasis, porcine cysticercosis, human cysticercosis), with a focus on recent advances in its diagnosis, management, and control. Read More

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http://dx.doi.org/10.1128/CMR.00085-19DOI Listing

Next-generation sequencing of cerebrospinal fluid for the diagnosis of neurocysticercosis.

Clin Neurol Neurosurg 2020 Jun 26;193:105752. Epub 2020 Feb 26.

Department of Neurology, Xijing Hospital, The Fourth Military Medical University, 15 Changle xi Road, Xi'an, 710032, China. Electronic address:

Objective: Neurocysticercosis (NCC) is the most common parasitic disease of the human central nervous system (CNS). However, a diagnosis of NCC may be hard to make if the specific clinical and routine neuroimaging manifestations are lacking, which hinders physicians from considering further immunodiagnostic tests.

Patients And Methods: Seven patients presented with fever, headache, nausea, cognitive decline, confusion, or progressive leg weakness. Read More

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http://dx.doi.org/10.1016/j.clineuro.2020.105752DOI Listing

Neurocysticercosis.

Saudi J Kidney Dis Transpl 2020 Jan-Feb;31(1):254-258

Department of Pharmacy Practice, Deccan School of Pharmacy, Hyderabad, Telangana, India.

Neurocysticercosis (NCC) is one of the common parasitic central nervous system (CNS) infections. Improperly cooked pork and eggs of the tapeworm Taenia solium, entering the body through the feco-oral route, are the common sources of its infection. Affected person may remain asymptomatic for long periods and can present with a variety of neurological manifestations, including focal neurological deficits and generalized seizures. Read More

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http://dx.doi.org/10.4103/1319-2442.279948DOI Listing

A Case Report of Intraparenchymal Neurocysticercosis in a Postpartum Female in Saudi Arabia.

Saudi J Med Med Sci 2020 Jan-Apr;8(1):60-63. Epub 2019 Dec 23.

Department of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Neurocysticercosis is a neurologic disease caused by infection with larvae of . It is most commonly transmitted by consumption of pork, water contaminated with or poor hygiene habits. As only few cases of neurocysticercosis have been documented in Saudi Arabia, the authors report a case of neurocysticercosis in a young Indian female residing in Saudi Arabia who presented with generalized tonic-clonic seizures 6 days after a normal vaginal delivery. Read More

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http://dx.doi.org/10.4103/sjmms.sjmms_65_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945319PMC
December 2019

Twenty-five years of evolution of standard diagnostic criteria for neurocysticercosis. How have they impacted diagnosis and patient outcomes?

Expert Rev Neurother 2020 Feb 25;20(2):147-155. Epub 2019 Dec 25.

School of Medicine, Universidad Espíritu Santo - Ecuador, Samborondón, Ecuador.

: Neurocysticercosis (NCC) is the most common helminthic infection of the central nervous system and a global public health problem. However, its diagnosis is complicated since histological demonstration of the parasite is often not feasible, clinical manifestations are nonspecific, most neuroimaging findings are not pathognomonic, and immunological tests have problems related to poor reliability. Unified chart of criteria is needed to standardize the diagnosis of NCC in different settings. Read More

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http://dx.doi.org/10.1080/14737175.2020.1707667DOI Listing
February 2020

Atypical radiological presentation of multiple cystic brain metastases from lung cancer simulating neurocysticercosis.

BMJ Case Rep 2019 Oct 5;12(10). Epub 2019 Oct 5.

Department of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University, Chieti, Italy

Brain metastases (BMs) are usually characterised by vasogenic oedema and mass effect, but cystic appearance can rarely occur, mimicking parasitosis, such as neurocysticercosis (NCC). A woman in her mid-50s was admitted for dizziness and upper left extremity paresis. Neuroimaging showed multiple cystic lesions consistent with multiple stages of NCC evolution, and empiric albendazole was started, without any clinical improvement. Read More

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http://dx.doi.org/10.1136/bcr-2019-231678DOI Listing
October 2019
1 Read

Value of Multimodal Imaging Approach to Diagnosis of Neurosarcoidosis.

Brain Sci 2019 Sep 21;9(10). Epub 2019 Sep 21.

Institute of Neurology, Magna Græcia University, 88100 Catanzaro, Italy.

Background: Neurosarcoidosis is a highly variable condition with many clinical and radiological manifestations, that can lead to difficult identification of isolated central nervous system (CNS) forms, because it could mimic inflammatory, infective or neoplastic disorders. Conventional magnetic resonance imaging (MRI) is gold standard to evaluate CNS involvement in neurosarcoidosis, despite the reported high sensitivity but low specificity in the diagnosis.

Case Presentation: Here, we describe a 52-year-old man that presented to our hospital with a 10-year history of focal seizures, progressive cognitive decline and motor impairment. Read More

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http://dx.doi.org/10.3390/brainsci9100243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827049PMC
September 2019
9 Reads

A Large Cohort of Neurocysticercosis in Shandong Province, Eastern China, 1997-2015.

Vector Borne Zoonotic Dis 2019 12 17;19(12):901-907. Epub 2019 Jul 17.

World Health Organization Collaborating Centre for Lymphatic Filariasis and Taeniasis/Cysticercosis, Shandong Institute of Parasitic Diseases, Shandong First Medical University & Shandong Academy of Medical Sciences, Jining, Shandong Province, China.

Neurocysticercosis (NCC) has a wide spectrum of neurologic and psychiatric manifestations, including epileptic seizures, high intracranial pressure, cognitive dysfunction, and meningoencephalitis. This study presents the clinical diagnosis of 2539 NCC patients in Shandong Province, Eastern China, from 1997 to 2015. The diagnosis was based primarily on clinical features, neuroimaging, immunology, and electroencephalogramy studies. Read More

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http://dx.doi.org/10.1089/vbz.2019.2447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882449PMC
December 2019
7 Reads

3D-Double-Inversion recovery detects perilesional gliosis better than 3D-FLAIR and postcontrast T1 imaging in calcified neurocysticercosis.

Neurol India 2019 Jan-Feb;67(1):136-141

Department of Radiology and Imaging, Fortis Memorial Research Institute, Gurugram, Haryana, India.

Background: Perilesional gliosis is an important substrate for seizures in patients harboring a calcified neurocysticercosis (NCC) lesion and magnetic resonance imaging (MRI) is useful for evaluating gliosis.

Aims: The purpose of this study was to evaluate the usefulness of double-inversion recovery (DIR) sequence for identifying perilesional gliosis.

Settings And Design: Hospital-based cross-sectional study. Read More

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http://dx.doi.org/10.4103/0028-3886.253614DOI Listing
December 2019
14 Reads

Three-dimensional double inversion recovery magnetic resonance sequence detects perilesional gliosis better than 3D-FLAIR and postcontrast T1 imaging in calcified neurocysticercosis.

Neurol India 2019 Jan-Feb;67(1):74-75

Department of Radiology, University Hospitals, Birmingham NHS Foundation Trust; Department of Radiology, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.4103/0028-3886.253592DOI Listing
February 2020
4 Reads

Structural Equation Modeling (SEM) of Cysticercosis in School-Aged Children in Tibetan Rural Farming Areas of Western China: Implications for Intervention Planning.

Int J Environ Res Public Health 2019 03 4;16(5). Epub 2019 Mar 4.

Division of Infectious Diseases and Geographic Medicine, Department of Medicine, Stanford University, Stanford, CA 94305, USA.

Neurocysticercosis (NCC) significantly contributes to morbidity in developing countries. We recently published a study of prevalence and risk factors in school-aged children in three mountainous areas in Sichuan province of western China. Using structural equation modeling (SEM) on data from that study to guide intervention planning, here we examine risk factors grouped into three broad interventional categories: sociodemographics, human behavior, and sources of pork and pig husbandry. Read More

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http://dx.doi.org/10.3390/ijerph16050780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6427563PMC
March 2019
12 Reads

Conglomerate Ring-Enhancing Lesions are Common in Solitary Neurocysticercosis and do not always Suggest Neurotuberculosis.

Ann Indian Acad Neurol 2019 Jan-Mar;22(1):67-72

Department of Biostatistics, All India Institute of Medical Sciences, New Delhi, India.

Background And Purpose: Differentiating between neurocysticercosis (NCC) and neurotuberculosis has serious therapeutic implications and this distinction relies heavily on neuroimaging. Few case reports discuss the conglomeration of ring-enhancing lesions (RELs) in patients with solitary NCC. The aim of our study is to describe the imaging findings of conglomerate RELs in a cohort of patients with solitary NCC, emphasizing the frequency of conglomeration. Read More

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http://dx.doi.org/10.4103/aian.AIAN_221_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327694PMC
January 2019
27 Reads

Comparison of complementary diagnostic tests in cerebrospinal fluid and serum for neurocysticercosis.

Heliyon 2018 Dec 1;4(12):e00991. Epub 2018 Dec 1.

Instituto de Investigación en Salud Pública y Zoonosis, Facultad de Medicina Veterinaria y Zootecnia, Universidad Central del Ecuador, Quito, Ecuador.

The role of immunologic tests in the diagnosis of neurocysticercosis (NC) is controversial and few studies have made comparisons among them. The objective of this study was to compare immunological tests in both serum and cerebrospinal fluid (CSF) for the diagnosis of NC. We conducted a case-control study in Cuenca, Ecuador, enrolling patients with NC (N = 24) and matching them with other neurosurgical patients (N = 18). Read More

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http://dx.doi.org/10.1016/j.heliyon.2018.e00991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278713PMC
December 2018
7 Reads

Overview of Taenia solium cysticercosis in West Africa.

Acta Trop 2019 Feb 7;190:329-338. Epub 2018 Dec 7.

Bristol Veterinary School, University of Bristol, Langford, Bristol, BS40 5DU, United Kingdom; School of Biological Sciences, Queen's University Belfast, 97, Lisburn Road, Belfast, BT9 7BL, United Kingdom.

Human and porcine cysticercosis is endemic in West Africa, where epilepsy is relatively common, but rarely reported due to fear of stigmatization. Neurocysticercosis, caused by Taenia solium, tends to affect the poor in developing countries and control is hampered by inadequate infrastructure and financial resources coupled with lack of adequate information about its significance and distribution. The risk factors for human cysticercosis are closely associated with the characteristics of smallholder or backyard pig farming systems prevalent in this region. Read More

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http://dx.doi.org/10.1016/j.actatropica.2018.12.012DOI Listing
February 2019
16 Reads

Detection of DNA in the Urine of Neurocysticercosis Patients.

Am J Trop Med Hyg 2019 02;100(2):327-329

W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.

Neurocysticercosis (NCC), caused by larvae that reside in the central nervous system, results in serious public health and medical issues in many regions of the world. Current diagnosis of NCC is complex requiring both serology and costly neuroimaging of parasitic cysts in the brain. This diagnostic pipeline can be problematic in resource-constrained settings. Read More

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http://dx.doi.org/10.4269/ajtmh.18-0706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367601PMC
February 2019
31 Reads

Application of diffusion tensor imaging in brain lesions: A comparative study of neoplastic and non-neoplastic brain lesions.

Neurol India 2018 Nov-Dec;66(6):1667-1671

Department of Biostatistics and Health Informatics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Purpose: To evaluate the role of diffusion tensor imaging (DTI) in the differentiation of neoplastic and non-neoplastic brain lesions, on the basis of DTI parameters, fractional anisotropy (FA) and mean diffusivity (MD) from the lesion (L) and the perilesional edema (PE).

Material And Methods: Patients with newly diagnosed 25 neoplastic [10 high grade gliomas (HGG), 11 metastases, 4 low grade glioma (LGG)] and 25 non-neoplastic [13 tuberculomas and 12 neurocysticercosis (NCC)] brain lesions underwent an MRI, including the DTI sequences. Fractional anisotropy from the lesion (FAL) and mean diffusivity from the lesion (MDL), as well as fractional anisotropy from the perilesional edema (FAPE), and mean diffusivity from the perilesional edema (MDPE) were calculated and quantified using region of interest (ROI) based assessment on DTI derived FA and MD parametric maps. Read More

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http://dx.doi.org/10.4103/0028-3886.246270DOI Listing
September 2019
4 Reads
1.084 Impact Factor

Neurocysticercosis: a reversible and rare cause of seizure in the developed world.

BMJ Case Rep 2018 Oct 30;2018. Epub 2018 Oct 30.

Faculty of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1136/bcr-2018-227479DOI Listing
October 2018
13 Reads

Perfusion magnetic resonance imaging in differentiation of neurocysticercosis and tuberculoma.

Neuroradiology 2019 Mar 30;61(3):257-263. Epub 2018 Oct 30.

Department of Pediatrics, Post Graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.

Purpose: Tuberculoma and neurocysticercosis (NCC) are two of the most common intracranial infections in developing countries and cause of seizures or focal neurological deficit. They often present on neuroimaging as ring-enhancing lesions, and in absence of typical imaging features, can cause significant diagnostic dilemma. Differentiation is extremely important to avoid empirical exposure to anti-tubercular treatment or nonspecific treatment causing disease progression. Read More

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http://link.springer.com/10.1007/s00234-018-2118-x
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http://dx.doi.org/10.1007/s00234-018-2118-xDOI Listing
March 2019
46 Reads
2.485 Impact Factor

Updates on the management of neurocysticercosis.

Curr Opin Infect Dis 2018 10;31(5):377-382

Center for Global Health, Universidad Peruana Cayetano Heredia.

Purpose Of Review: The goal of this review is highlight recent developments regarding neurocysticercosis, including recently developed guidelines.

Recent Findings: Recent diagnostic criteria highlight the importance of neuroimaging in establishing a diagnosis. Monoclonal antibody-based antigen detection and the enzyme-linked immunotransfer blot can be confirmatory. Read More

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http://Insights.ovid.com/crossref?an=00001432-900000000-9925
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http://dx.doi.org/10.1097/QCO.0000000000000480DOI Listing
October 2018
42 Reads

Clinical topography relationship in patients with parenchymal neurocysticercosis and seizures.

Epilepsy Res 2018 09 28;145:145-152. Epub 2018 Jun 28.

Center for Global Health - Tumbes, Universidad Peruana Cayetano Heredia, Lima, Peru; Cysticercosis Unit, Department of Transmissible Diseases, Instituto Nacional de Ciencias Neurologicas, Lima, Peru; Department of Microbiology, School of Sciences, Universidad Peruana Cayetano Heredia, Lima, Peru.

Objective: Discordances between imaging findings of parenchymal neurocysticercosis and seizure expression have been reported, and as such the possibility that neurocysticercosis and seizures may frequently coexist by chance has been raised. In this study, we evaluate the topographic relationship between seizure foci based on semiology and electroencephalography with the location of parenchymal neurocysticercotic lesions.

Methods: Seizure information, neuroimaging (computed tomography and magnetic resonance imaging [MRI]) and electroencephalographic data from three randomized clinical trials of individuals with parenchymal neurocysticercosis and focal seizures were analyzed. Read More

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http://dx.doi.org/10.1016/j.eplepsyres.2018.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063828PMC
September 2018
21 Reads

Next-Generation Sequencing of Cerebrospinal Fluid for the Diagnosis of Neurocysticercosis.

Front Neurol 2018 19;9:471. Epub 2018 Jun 19.

Department of Neurology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Neurocysticercosis (NCC) is the most common helminthic infection of the central nervous system (CNS). The diagnosis of NCC is sometimes challenging due to its heterogenous clinical manifestations and the variable sensitivity and specificity of neuroimaging and serological tests. Next-generation sequencing (NGS) of cerebrospinal fluid (CSF) was used to detect pathogens in patients with clinically suspected CNS infections. Read More

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http://dx.doi.org/10.3389/fneur.2018.00471DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6018529PMC
June 2018
28 Reads

Neurocysticercosis in Children with Seizures: A Cross-Sectional Study.

Int J Pediatr 2018 21;2018:1030878. Epub 2018 May 21.

Department of Pediatrics, Universal College of Medical Sciences, Bhairahawa 32900, Nepal.

Background: Neurocysticercosis (NCC), a common cause of seizures in children from low and middle income countries (LMICs), if not diagnosed and treated early enough may lead to considerable morbidity and mortality. There is a lack of data on the prevalence of NCC and its clinical characteristics among those with seizure in South-Western Nepal.

Aims And Objectives: To study the prevalence and clinical characteristics of NCC in children with seizures. Read More

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http://dx.doi.org/10.1155/2018/1030878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987327PMC
May 2018
53 Reads

Solitary Brain Mass in a Patient with Seizures: An Unexpected Infectious Etiology.

Diseases 2018 Jun 22;6(3). Epub 2018 Jun 22.

Division of Infectious Diseases, Department of Medicine, Huntsville Hospital, Huntsville, AL 35801, USA.

Neurocysticercosis is a parasitosis caused by the larval stage of the pork tapeworm The diagnosis is challenging as morphology on neuroimaging can be inconclusive and serology is frequently negative. We describe the case of a 24-year old Hispanic man who presented with seizures and loss of consciousness. Magnetic resonance imaging (MRI) showed a cystic mass in right frontal lobe. Read More

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http://dx.doi.org/10.3390/diseases6030054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163356PMC
June 2018
15 Reads

The Many Faces of Neurocysticercosis.

J Neurol Sci 2018 07 12;390:75-76. Epub 2018 Apr 12.

Department of Neurology, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address:

Neurocysticercosis (NCC) is the most common parasitic disease of the central nervous system, and one of the most common causes of epilepsy worldwide. The radiologic appearance of neurocysticercosis varies depending on the stage of the disease, and the stage of the disease determines the appropriate treatment. In this article, we review key neuroimaging characteristics of the stages of NCC (vesicular, colloidal, granular, and calcified) and treatment principles for these different stages of the disease. Read More

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http://dx.doi.org/10.1016/j.jns.2018.04.018DOI Listing
July 2018
10 Reads

Role of Immuno-Polymerase Chain Reaction (I-PCR) in Resolving Diagnostic Dilemma Between Tuberculoma and Neurocysticercosis: A Case Report.

Am J Case Rep 2018 May 24;19:599-603. Epub 2018 May 24.

Centre for Biotechnology, Maharshi Dayanand University (MDU), Rohtak, Haryana, India.

BACKGROUND Tuberculoma and neurocysticercosis (NCC) often show similar clinical and neuroimaging features. Differential diagnosis of these 2 diseases is imperative, as tuberculoma is an active infection that requires immediate anti-tubercular therapy (ATT). CASE REPORT We present the case of a 17-year-old Indian girl with fever, severe headache, and right 6th cranial nerve palsy. Read More

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http://dx.doi.org/10.12659/AJCR.908624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994961PMC
May 2018
22 Reads

Atypical presentation of posterior reversible encephalopathy syndrome: Two cases.

J Anaesthesiol Clin Pharmacol 2018 Jan-Mar;34(1):120-122

Department of Anaesthesiology, Lady Hardinge Medical College and Smt. SSK Hospital, New Delhi, India.

Posterior reversible encephalopathy syndrome (PRES) is a clinico-neuroradiological entity, first described in 1996. It is commonly associated with systemic hypertension, intake of immunosuppressant drugs, sepsis and eclampsia and preeclampsia. Headache, alteration in consciousness, visual disturbances and seizures are common manifestations of PRES. Read More

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http://dx.doi.org/10.4103/0970-9185.173351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885427PMC
April 2018
15 Reads

Neurocysticercosis: the good, the bad, and the missing.

Expert Rev Neurother 2018 04 14;18(4):289-301. Epub 2018 Mar 14.

f Departamento de Medicina , Universidade de Taubaté , São Paulo , Brazil.

Introduction: Neurocysticercosis (NC) is a neglected disease that contributes substantially to neurological morbidity/mortality in lower-income countries and increasingly among high-income countries due to migration. Many advances have been made in understanding NC, but unanswered questions remain Areas covered: This review discusses the epidemiology, pathophysiology, immunology, diagnosis, treatment, and eradication of NC. Expert commentary: The global NC prevalence remains unknown and needs proper ascertainment. Read More

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http://dx.doi.org/10.1080/14737175.2018.1451328DOI Listing
April 2018
21 Reads

Seroprevalence of human cysticercosis in Jataí, Goiás state, Brazil.

Braz J Infect Dis 2018 Mar - Apr;22(2):146-149. Epub 2018 Feb 10.

Universidade Federal de Goiás, Laboratório de Imunologia, Jataí, GO, Brazil. Electronic address:

The Taenia solium cysticercosis affects millions of people worldwide and is considered a public health problem, especially in developing countries. The diagnosis of neurocysticercosis is complex and involves the analysis of epidemiological, clinical, neuroimaging, and immunological host data. Neurocysticercosis is endemic in Brazil, and is related to the cause of death mainly in the Southeast, South, and Central-West regions. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S14138670173085
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http://dx.doi.org/10.1016/j.bjid.2018.01.002DOI Listing
July 2018
25 Reads

Giant Intraparanchymal Neurocysticercosis.

J Assoc Physicians India 2017 Nov;65(11):85-86

Post graduates in General Medicine, Govt. Mohan Kumaramangalam Medical College Hospital, Salem, Tamil Nadu.

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November 2017
20 Reads

Neuroimaging of Dilated Perivascular Spaces: From Benign and Pathologic Causes to Mimics.

J Neuroimaging 2018 03 27;28(2):139-149. Epub 2017 Dec 27.

Department of Radiology, Division of Neuroradiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

Perivascular spaces (PVSs), also known as Virchow-Robin spaces, are pial-lined, fluid-filled structures found in characteristic locations throughout the brain. They can become abnormally enlarged or dilated and in rare cases can cause hydrocephalus. Dilated PVSs can pose a diagnostic dilemma for radiologists because of their varied appearance, sometimes mimicking more serious entities such as cystic neoplasms, including dysembryoplastic neuroepithelial tumor and multinodular and vacuolating neuronal tumor, or cystic infections including toxoplasmosis and neurocysticercosis. Read More

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http://doi.wiley.com/10.1111/jon.12493
Publisher Site
http://dx.doi.org/10.1111/jon.12493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398334PMC
March 2018
28 Reads

Spontaneously Arrested Transmission of Cysticercosis in a Highly Endemic Village with a Very Low Migration Rate.

Am J Trop Med Hyg 2018 03 14;98(3):776-778. Epub 2017 Dec 14.

Cysticercosis Unit, Instituto Nacional de Ciencias Neurológicas, Lima, Perú.

cysticercosis is difficult to eliminate without interventions or societal development. Atahualpa is a rural Ecuadorian village with documented low migration rate, where domestic pig raising is common and human cysticercosis is endemic. To assess neurocysticercosis (NCC) prevalence, 1,273 villagers aged ≥ 20 years underwent neuroimaging studies, which showed calcified lesions in 121 (9. Read More

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http://dx.doi.org/10.4269/ajtmh.17-0723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930905PMC
March 2018
30 Reads

MicroRNAs in Neurocysticercosis: Insights as Promising Agents in Host-Parasite Interaction and Their Potential as Biomarkers.

Front Microbiol 2017 29;8:1905. Epub 2017 Sep 29.

Neurocysticercosis Lab, Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, Lima, Peru.

MicroRNAs (miRNAs) are short, endogenous, non-coding, single-stranded RNAs involved in post-transcriptional gene regulation. Although, several miRNAs have been identified in parasitic helminths, there is little information about their identification and function in . Furthermore, the impact of miRNAs in neurocysticercosis, the brain infection caused by larvae of is still unknown. Read More

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http://journal.frontiersin.org/article/10.3389/fmicb.2017.01
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http://dx.doi.org/10.3389/fmicb.2017.01905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626859PMC
September 2017
13 Reads
1 Citation
3.941 Impact Factor

Fourth ventricle neurocysticercosis: Rigid endoscopic management. Description of direct transcerebellar approach.

Surg Neurol Int 2017 26;8:232. Epub 2017 Sep 26.

Neurosurgery Department, Centro Médico "Lic. Adolfo López Mateos", Instituto de Salud del Estado de México, Av. Nicolas San Juan s/n Ex Hacienda La Magdalena, Estado de México, México.

Background: Endoscopy has gained a crucial role in high specialty neurosurgery during the last decades. At present, there are well-defined flexible neuroendoscopic procedures to treat ventricular and subarachnoid space pathologies. Neurocysticercosis is recognized as a common cause of neurologic disease in developing countries and the United States. Read More

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http://dx.doi.org/10.4103/sni.sni_251_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629842PMC
September 2017
56 Reads

Antibody Banding Patterns of the Enzyme-Linked Immunoelectrotransfer Blot and Brain Imaging Findings in Patients With Neurocysticercosis.

Clin Infect Dis 2018 01;66(2):282-288

School of Public Health and Management, Universidad Peruana Cayetano Heredia, Lima, Peru.

Background: The enzyme-linked immunoelectrotransfer blot (EITB) assay is the reference serological test for neurocysticercosis (NCC). A positive result on EITB does not always correlate with the presence of active infections in the central nervous system (CNS), and patients with a single viable brain cyst may be EITB negative. Nonetheless, EITB antibody banding patterns appears to be related with the expression of 3 protein families of Taenia solium, and in turn with the characteristics of NCC in the CNS (type, stage, and burden of viable cysts). Read More

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http://dx.doi.org/10.1093/cid/cix774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850523PMC
January 2018
119 Reads
2 Citations
8.890 Impact Factor

Clinical and neuroimaging predictors of seizure recurrence in solitary calcified neurocysticercosis: A prospective observational study.

Epilepsy Res 2017 11 20;137:78-83. Epub 2017 Sep 20.

Department of Radiology and Imaging, Fortis Memorial Research Institute, Gurgaon, India.

Background: Solitary calcified neurocysticercosis is a common cause of seizures in the developing countries. Factors responsible for seizure recurrence in patients with solitary calcified neurocysticercosis are not known. We evaluated the clinical, neuroimaging and biochemical predictors of seizure recurrence. Read More

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http://dx.doi.org/10.1016/j.eplepsyres.2017.09.010DOI Listing
November 2017
74 Reads

Pediatric Neurocysticercosis.

Indian J Pediatr 2019 Jan 20;86(1):76-82. Epub 2017 Sep 20.

Pediatric Neurology and Neurodevelopment Unit, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

Neurocysticercosis is the most common helminth infection of nervous system in humans caused by the encysted larvae of Taenia solium. It is a major cause of epilepsy in tropical areas and the most common cause of focal-onset seizures in North Indian children. Children with neurocysticercosis have pleomorphic manifestations depending on the location, number and viability of the cysts and host response. Read More

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http://dx.doi.org/10.1007/s12098-017-2460-8DOI Listing
January 2019
30 Reads

Head CT findings at a public hospital in rural Haiti.

J Neurol Sci 2017 Aug 20;379:327-330. Epub 2017 Jun 20.

Harvard Medical School, Boston, MA, USA; Hôpital Universitaire de Mirebalais, Partners In Health, Haiti; Department of Neurology, Brigham and Women's Hospital, USA. Electronic address:

Background: Neuroimaging is often unavailable in low-income countries, creating challenges for precise diagnosis of neurologic disease in individual patients, and impeding acquisition of precise neuroepidemiologic data for program and policy development.

Methods: We analyzed reports from 3614 head CTs performed between July 2013 and January 2016 at Hôpital Universitaire de Mirebalais, a public academic hospital in rural Haiti, extracting patients' age, study indication, and radiologic findings.

Results: The most common indications for head CT were headache (27%), trauma (19. Read More

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http://dx.doi.org/10.1016/j.jns.2017.06.029DOI Listing
August 2017
17 Reads

Computerized Axial Tomography Findings in Children with Afebrile Seizures: A Hospital Based Study at Eastern Nepal.

J Nepal Health Res Counc 2017 Jan;15(1):61-66

Department of Pediatrics and Adolescent Medicine, B.P. Koirala Institute of Health Sciences, Sunsari, Nepal.

Background: Computerized Tomography can be performed in resource limited areas where Magnetic Resonance Imaging is less practical. This study was conducted to find out the proportion of cases with abnormal CT scan and findings of CT scan in children with afebrile seizures in a resource limited area.

Methods: This prospective study was conducted from 1st July 2009 to 31st March 2014 in a university hospital of Nepal. Read More

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http://dx.doi.org/10.3126/jnhrc.v15i1.18015DOI Listing
January 2017
8 Reads

Parkinsonism and other movement disorders in 23 cases of neurocysticercosis.

Parkinsonism Relat Disord 2017 Sep 20;42:47-53. Epub 2017 Jun 20.

Neurology Department, Hospital Eugenio Espejo, Quito, Ecuador; SENESCYT, Ecuador; CIBERNED, Spain; Carlos III Health Institute, Madrid, Spain.

Introduction: Parkinsonism and other movement disorders have been occasionally described in neurocysticercosis (NCC) but their clinical features and pathogenesis are not well understood.

Methods: This is a descriptive study conducted over 20 years. We studied 590 consecutive patients from the NCC Registry at Eugenio Espejo Hospital, Quito, Ecuador, and found 23 subjects who developed movement disorders. Read More

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http://dx.doi.org/10.1016/j.parkreldis.2017.06.009DOI Listing
September 2017
11 Reads

[An underestimated cause of seizure in Europe].

Rev Med Suisse 2017 Jun;13(567):1263-1265

Service d'accueil des urgences, Hôpitaux universitaires de Strasbourg, Hôpital de Hautepierre, avenue Molière 1, 67098 Strasbourg, France.

Seizures are very common in the Emergency Department (ED). We present here a case of a young woman with neurocysticercosis ; a worldwide and nearly endemic cause of seizure in the southern hemisphere. Clinical manifestations are very different between patients from asymptomatic to life-threatening hydrocephalus. Read More

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June 2017
24 Reads

Intracranial Infectious and Inflammatory Diseases Presenting as Neurosurgical Pathologies.

Neurosurgery 2017 Jul;81(1):10-28

Department of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, Georgia.

There are many infectious and inflammatory processes affecting the central nervous system that can simulate other neurosurgical pathologies (e.g. tumor) and may precipitate a brain biopsy for definitive diagnosis if not suspected a priori. Read More

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https://academic.oup.com/neurosurgery/article-lookup/doi/10.
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http://dx.doi.org/10.1093/neuros/nyx201DOI Listing
July 2017
38 Reads

[Racemose neurocysticercosis: Neuroimaging guides the diagnosis].

Biomedica 2017 Apr 1;37(0):26-32. Epub 2017 Apr 1.

Sección de Neurología, Departamento de Medicina Interna, Hospital Universitario de San Vicente Fundación, Universidad de Antioquia, Medellín, Colombia.

Neurocysticercosis is the leading cause of parasitosis of the central nervous system and acquired epilepsy in developing countries. The clinical manifestations of neurocysticercosis, especially its racemose variant, are pleomorphic and unspecific, characteristics that hinder the diagnosis and make it a challenge for the clinician.The objective of this report was to describe two cases of racemose neurocysticercosis in which neuroimaging led to the definitive diagnosis. Read More

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http://dx.doi.org/10.7705/biomedica.v37i2.2983DOI Listing
April 2017
68 Reads

Solitary Cysticercal Cyst Inside the Blake's Pouch Remnant of Mega Cisterna Magna with Associated Aqueductal Stenosis: Clinical and Management Implications.

World Neurosurg 2017 Jun 19;102:693.e1-693.e5. Epub 2017 Apr 19.

Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.

Background: Intraventricular and subarachnoid forms represent the relatively complex, albeit uncommon, manifestations of central nervous system involvement by cysticercal cysts. Cysticercal encystation inside the Blake's pouch remnant of mega cisterna magna (MCM) remains an extremely rare clinical scenario that, to the best of our knowledge, has not been reported previously.

Case Presentation: A 12-year-old boy presented with acute worsening and subsequent spontaneous resolution of his compensated hydrocephalus. Read More

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http://dx.doi.org/10.1016/j.wneu.2017.04.067DOI Listing
June 2017
36 Reads

T2 relaxometry helps prognosticate seizure outcome in patients with solitary cerebral cysticercosis.

J Neurol Sci 2017 May 27;376:1-6. Epub 2017 Feb 27.

Department of Biostatistics, National Institute of Mental Health and NeuroSciences, Bangalore 560 029, India.

Objective: Correlate serial T2 relaxometry (T2R) values with long term seizure outcome in patients with solitary cerebral cysticercosis (SCC) in order to establish its usefulness as a prognostic marker in these patients.

Methods: Patients with new-onset seizures due to SCC were imaged serially using a pre-determined MRI protocol at enrolment and after 3, 6, 12 and 24months. T2 relaxometry was performed using a dual echo sequence with maps generated manually from the measured image intensities at the level of the lesion. Read More

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http://dx.doi.org/10.1016/j.jns.2017.02.052DOI Listing
May 2017
7 Reads

The causal relationship between neurocysticercosis infection and the development of epilepsy - a systematic review.

Infect Dis Poverty 2017 Apr 5;6(1):31. Epub 2017 Apr 5.

Division of Infection and Pathway Medicine, Edinburgh Infectious Diseases, Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, Chancellor's Building, 49 Little France Crescent, Edinburgh, EH16 4SB, Scotland, UK.

Background: Neurocysticercosis (NCC) is a parasitic infection of the human central nervous system, the most common form of which involves infection of the brain parenchyma with the larval form of the Taenia solium tapeworm. A causal relationship between such an NCC infection and the development of epilepsy in infected individuals is acknowledged, in part supported by high levels of comorbidity in endemic countries worldwide.

Methods: This study undertook a systematic review and critical analysis of the NCC-epilepsy relationship with the primary objective of quantifying the risk of developing epilepsy following NCC infection. Read More

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http://dx.doi.org/10.1186/s40249-017-0245-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381143PMC
April 2017
13 Reads

Disseminated neurocysticercosis presenting as acute stress reaction.

Ind Psychiatry J 2016 Jan-Jun;25(1):110-112

Department of Psychiatry, University College of Medical Sciences and Guru Teg Bahadur Hospital, Dilshad Garden, New Delhi, India.

Neurocysticercosis is the most common and preventable parasitic infection of the central nervous system, but disseminated cysticercosis is said to be rare. We report a case of a 31-year-old male, who presented with anxiety manifestations temporally associated with stress related to job. After initial clinical improvement, he presented with an incapacitating headache which was diagnosed as disseminated neurocysticercosis after thorough evaluation and investigations. Read More

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http://dx.doi.org/10.4103/0972-6748.196047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5248410PMC
February 2017
12 Reads

Neurocysticercosis: Diagnostic problems & current therapeutic strategies.

Indian J Med Res 2016 Sep;144(3):319-326

Department of Neurological Sciences, Christian Medical College & Hospital, Vellore, India.

Neurocysticercosis (NCC) is the most common single cause of seizures/epilepsy in India and several other endemic countries throughout the world. It is also the most common parasitic disease of the brain caused by the cestode Taenia solium or pork tapeworm. The diagnosis of NCC and the tapeworm carrier (taeniasis) can be relatively inaccessible and expensive for most of the patients. Read More

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http://dx.doi.org/10.4103/0971-5916.198686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5320837PMC
September 2016
19 Reads

Validity of a PCR assay in CSF for the diagnosis of neurocysticercosis.

Neurol Neuroimmunol Neuroinflamm 2017 Mar 16;4(2):e324. Epub 2017 Jan 16.

Facultad de Ciencias Médicas (A. Carpio, A. Campoverde, L.G., L.M.P.), Universidad de Cuenca, Ecuador; GH Sergievsky Center (A. Carpio), College of Physicians and Surgeons, Columbia University; Department of Epidemiology and Biostatistics (M.L.R.), CUNY Graduate School of Public Health and Health Policy, City University of New York, NY; Hospital del Instituto Ecuatoriano de Seguridad Social (L.M.P., N.L.), José Carrasco Arteaga; Hospital Vicente Corral Moscoso (M.P., J.A.), Ministerio de Salud Pública; Hospital Santa Inés (S.L.); Clínica Santa Ana (L.C.V.); and Hospital Universitario del Río (A.M.T., P.P.-T.), Cuenca, Ecuador.

Objective: To prospectively evaluate the validity of a PCR assay in CSF for the diagnosis of neurocysticercosis (NC).

Methods: We conducted a multicenter, prospective case-control study, recruiting participants from 5 hospitals in Cuenca, Ecuador, from January 2015 to February 2016. Cases fulfilled validated diagnostic criteria for NC. Read More

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http://dx.doi.org/10.1212/NXI.0000000000000324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241005PMC
March 2017
43 Reads

The Association Between Neurocysticercosis and Hippocampal Atrophy is Related to Age.

Am J Trop Med Hyg 2017 Jan 14;96(1):243-248. Epub 2016 Nov 14.

Center for Global Health, Tumbes, Perú.

Neurocysticercosis (NCC) has been associated with hippocampal atrophy, but the prevalence and pathogenic mechanisms implicated in this relationship are unknown. Using a population-based, case-control study design, residents in a rural village (Atahualpa) aged ≥ 40 years with calcified NCC were identified as cases and paired to NCC-free individuals (control subjects) matched by age, sex, and level of education. Cases and control subjects underwent magnetic resonance imaging for hippocampal rating according to the Scheltens' scale for medial temporal atrophy and were interviewed to identify those with a clinical seizure disorder. Read More

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http://dx.doi.org/10.4269/ajtmh.16-0689DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239702PMC
January 2017
73 Reads