324 results match your criteria Neuroimaging in Neurocysticercosis

Non invasive tests for diagnosis of parasitic infections of CNS.

Indian J Pathol Microbiol 2022 May;65(Supplement):S164-S175

Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore, Karnataka, India.

Central nervous system (CNS) infections are among the most devastating diseases with high mortality and morbidity. In the pre-human immunodeficiency virus (HIV) era, the occurrence of CNS infections was very infrequent. However, in the past four decades or so, with a global increase in the immunocompromised population, the incidence of opportunistic infections of the CNS has changed. Read More

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Complex neurocysticercosis lesions on imaging: Explained through correlative histomorphology.

Neuroradiol J 2022 May 10:19714009221098372. Epub 2022 May 10.

Departmentof Pathology 80369IGMC, Shimla, India.

Objectives: Neurocysticercosis, the commonest neuro-parasite, sometimes presents as complex ring enhancing lesion causing diagnostic dilemma. We aim to establish radio-histo-morphological equivalents of early events in degeneration of the parasite to explain such imaging phenotypes.

Methods: We compared patterns of degeneration in 23 randomly selected complex NCC on MRI with histo-morphology in 30 cysts obtained from an unrelated post mortem brain. Read More

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Quality of life in patients with symptomatic epilepsy due to neurocysticercosis.

Epilepsy Behav 2022 Jun 25;131(Pt A):108668. Epub 2022 Apr 25.

Cysticercosis Unit, Instituto Nacional de Ciencias Neurológicas, Lima, Peru; Center for Global Health, Universidad Peruana Cayetano Heredia, Lima, Peru.

Background: Neurocysticercosis (NCC) is a common cause of late-onset epilepsy worldwide, but there is still minimal information regarding its impact on a patient's quality of life. This study evaluated quality of life in a series of patients with epilepsy secondary to NCC using the QOLIE (Quality of Life in Epilepsy)-31 questionnaire.

Methodology: This cross-sectional study included 155 Peruvian patients between 16 and 70 years of age with epilepsy due to viable intraparenchymal NCC, who enrolled in two trials of anti-parasitic treatment during the period 2006-2011. Read More

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Diagnosis and management of cerebral sparganosis: An uncommon parasitic infection of the brain.

Radiol Case Rep 2022 Jun 4;17(6):1874-1880. Epub 2022 Apr 4.

Mark and Mary Stevens Neuroimaging and Informatics Institute, University of Southern California, Los Angeles, CA, USA.

Cerebral sparganosis is a rare parasitic infection that can be difficult to diagnose due to similarities in clinical and imaging features with more common parasitic infections, such as neurocysticercosis, and other neurologic conditions. We present a case of a 61-year-old female with a verified case of cerebral sparganosis. We also review the current literature regarding the sparganosis infection process, imaging features, and unique therapeutic options. Read More

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A Neurocysticercosis Infestation Masquerading as Malignant Brain Tumour.

Ann Indian Acad Neurol 2021 Nov-Dec;24(6):970-972. Epub 2020 Nov 7.

Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.

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November 2020

Neurocysticercosis: new insight into an old pathology.

BMJ Case Rep 2022 03 14;15(3). Epub 2022 Mar 14.

Radiodiagnosis, PGIMER, Chandigarh, India

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Solitary Neurocysticercosis Presenting with Focal Seizure and Secondary Generalized Tonic-Clonic Seizure.

Am J Case Rep 2022 Mar 14;23:e935483. Epub 2022 Mar 14.

Department of Parasitology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

BACKGROUND Neurocysticercosis is the most common central nervous system infection in developing countries. A wide array of clinical manifestations, ranging from asymptomatic to severe neurological symptoms, is observed in patients diagnosed with neurocysticercosis, depending on the number of lesions, cyst location, cyst stage, parasite genotype, and host immunity. CASE REPORT We report the case of a 25-year-old Burmese man who presented with focal seizure and secondary generalized tonic-clonic seizure. Read More

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Evaluating the Association of Calcified Neurocysticercosis and Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis in a Large Cohort of Patients With Epilepsy.

Front Neurol 2021 27;12:769356. Epub 2022 Jan 27.

Graduate Program in Medicine: Medical Sciences, Universidade Federal Do Rio Grande Do Sul, Porto Alegre, Brazil.

Background: Neurocysticercosis (NCC) is a parasitic infection of the central nervous system that has been associated with mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS). However, this association has not been completely established.

Objective: To evaluate the prevalence of calcified NCC (cNCC), its characteristics and a possible association between cNCC and MTLE-HS in a cohort of 731 patients with epilepsy. Read More

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January 2022

Neglected and (re-)emergent infections of the CNS i n low-/middle-income countries.

Infez Med 2021 10;29(4):513-525. Epub 2021 Dec 10.

Neuroimaging Department, Tulane University, New Orleans, USA.

Low- and middle-income countries (LMIC) have suffered from long-term health system deficiencies, worsened by poor living conditions, lack of sanitation, a restricted access to health facilities and running water, overcrowding, and overpopulation. These factors favor human displacement and deepen marginalization; consequently, their population endures a high burden of infectious diseases. In this context, the current epidemiological landscape and its impact on health and economic development are not promissory, despite the commitment by the international community to eradicate neglected tropical infections - especially tuberculosis and malaria, by 2030. Read More

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December 2021

Neurocysticercosis: a contemporary presentation of the neuroimaging main stages.

BMJ Case Rep 2022 Feb 9;15(2). Epub 2022 Feb 9.

Neuroradiology Unit - Medical Imaging Department, Centro Hospitalar e Universitario de Coimbra EPE, Coimbra, Portugal.

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February 2022

Evaluation of recombinant glutathione transferase 26 kDa, thioredoxin-1, and endophilin B1 of Taenia solium in the diagnosis of human neurocysticercosis.

Acta Trop 2022 Mar 26;227:106294. Epub 2021 Dec 26.

Departamento de Microbiología y Parasitología. Edificio A, 2o Piso, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad Universitaria, A.P. 70228, CDMX 04510, Mexico. Electronic address:

Neurocysticercosis caused by Taenia solium larvae is a neglected disease that persists in several countries, including Mexico, and causes a high disability-adjusted life year burden. Neuroimaging tools such as computed tomography and magnetic resonance imaging are the most efficient for its detection, but low availability and high costs in most endemic regions limit their use. Serological methods such as lentil lectin-purified glycoprotein enzyme-linked immunoelectrotransfer blot antibody detection and monoclonal antibody-based enzyme-linked immunosorbent assays for HP10 antigen detection have been useful in supporting the diagnosis of this disease. Read More

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Improved Diagnosis of Viable Parenchymal Neurocysticercosis by Combining Antibody Banding Patterns on Enzyme-Linked Immunoelectrotransfer Blot (EITB) with Antigen Enzyme-Linked Immunosorbent Assay (ELISA).

J Clin Microbiol 2022 02 1;60(2):e0155021. Epub 2021 Dec 1.

Center for Global Health, Universidad Peruana Cayetano Heredia, Lima, Peru.

The diagnosis of neurocysticercosis (NCC) depends on neuroimaging and serological confirmation. While antibody detection by enzyme-linked immunoelectrotransfer blot (EITB) fails to predict viable NCC, EITB banding patterns provide information about the host's infection course. Adding antigen enzyme-linked immunosorbent assay (Ag-ELISA) results to EITB banding patterns may improve their ability to predict or rule out of viable NCC. Read More

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February 2022

Neurocysticercosis in Children.

Pediatr Clin North Am 2022 02;69(1):115-127

Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Ratchathewi, Bangkok 10400, Thailand.

Neurocysticercosis is one of the most common parasitic infections in the central nervous system in children. The usual clinical manifestation is new-onset focal seizure. However, there are other multiple clinical manifestations, such as increased intracranial pressure, meningoencephalitis, spinal cord syndrome, and blindness. Read More

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February 2022

My experience on taeniasis and neurocysticercosis.

Trop Parasitol 2021 Jul-Dec;11(2):71-77. Epub 2021 Oct 20.

Department of Microbiology, Apollomedics Super Speciality Hospital, Lucknow, Uttar Pradesh, India.

Taeniasis and neurocysticercosis (NCC) are major public health problems in developing countries. NCC is the leading cause of community-acquired active epilepsy. NCC may present as a medical emergency, especially when there is cysticercotic encephalitis or raised intracranial hypertension. Read More

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October 2021

Neurocysticercosis in a Japanese woman with lung cancer who repeatedly visited endemic countries.

BMC Infect Dis 2021 Oct 18;21(1):1077. Epub 2021 Oct 18.

Department of Neurosurgery, Tokushima Municipal Hospital, 2-34, Kitajyosanjima-cho, Tokushima, 770-0812, Japan.

Background: Taenia solium, present in most developing countries, infects many individuals and may result in their death. Neurocysticercosis (NCC) develops after invasion of the brain by parasitic larvae. It is the most common parasitic disease of the human central nervous system. Read More

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October 2021

Incidence of Adult-Onset Epilepsy and the Contributory Role of Neurocysticercosis in a Five-Year, Population-Based, Prospective Study in Rural Ecuador.

Am J Trop Med Hyg 2021 10 11;106(1):208-214. Epub 2021 Oct 11.

Biostatistics/Epidemiology, Freenome, Inc., South San Francisco, California.

This prospective cohort study aimed to assess incidence and etiology of adult-onset epilepsy in previously seizure-free Atahualpa residents aged ≥ 20 years. Persons with adult-onset epilepsy occurring over 5 years were identified from annual door-to-door surveys and other overlapping sources. Those who emigrated or declined consent were excluded at the administrative censoring date of the last survey when these subjects were interviewed. Read More

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October 2021

Role of neuroimaging in children with first unprovoked seizure: A prospective observational study.

Epilepsy Behav 2021 Oct 4;124:108317. Epub 2021 Oct 4.

Department of Radio-diagnosis, King George's Medical University, Lucknow, India.

Objective: To evaluate the incidence and type of neuroimaging abnormalities in first unprovoked seizure (FUS) in children. To investigate the association of neuroimaging abnormalities with clinical variables.

Methods: A prospective observational study enrolled children aged 6 months-14 years with FUS over one year at a tertiary-care teaching hospital, Northern India and subjected them to neuroimaging. Read More

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October 2021

Neglected Parasitic Infections: What Family Physicians Need to Know-A CDC Update.

Am Fam Physician 2021 Sep;104(3):277-287

Centers for Disease Control and Prevention, Atlanta, GA, USA.

Chagas disease, cysticercosis, and toxoplasmosis affect millions of people in the United States and are considered neglected parasitic diseases. Few resources are devoted to their surveillance, prevention, and treatment. Chagas disease, transmitted by kissing bugs, primarily affects people who have lived in Mexico, Central America, and South America, and it can cause heart disease and death if not treated. Read More

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September 2021

Current Diagnostic Criteria for Neurocysticercosis.

Res Rep Trop Med 2021 10;12:197-203. Epub 2021 Aug 10.

Center for Global Health, Universidad Peruana Cayetano Heredia, Lima, Perú.

Neurocysticercosis (NCC) causes significant neurological morbidity around the world, and is the most common preventable factor for epilepsy in adults. It is endemic in most developing countries, and also diagnosed with some frequency in industrialized countries because of travel and migration. The clinical manifestations of NCC are extremely variable and may include almost any neurological symptom, depending on the number of lesions, location, size and evolutive stage of the infecting parasitic larvae and the immune response of the host. Read More

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Management of Neurocysticercosis in Children: Association of Child Neurology Consensus Guidelines.

Indian Pediatr 2021 Sep 2;58(9):871-880. Epub 2021 Aug 2.

Pediatric Neurology and Neurodevelopment, Medanta the Medicity, Gurugram, Haryana. Correspondence to: Prof Pratibha Singhi, Professor and Chief, Pediatric Neurology and Neurodevelopment, Medanta the Medicity, Gurugram, India.

Justification: Neurocysticercosis (NCC) is a significant problem in India and other developing countries; however, several aspects of this disease have no clear, practical guidelines. There is a need for pragmatic guidelines, summarizing the available evidence, and filling in the gaps in evidence with expert advice to manage children with neurocysticercosis.

Process: An expert group (16 members) and a writing group (8 members) was constituted, consisting of members with varied expertise. Read More

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September 2021

Neurocysticercosis and HIV/AIDS co-infection: A scoping review.

Trop Med Int Health 2021 10 23;26(10):1140-1152. Epub 2021 Aug 23.

Department of Neurology, Center for Global Health, School of Medicine, Technical University of Munich, Munich, Germany.

Objectives: Neurocysticercosis (NCC) and human immunodeficiency virus (HIV) have a high disease burden and are prevalent in overlapping low- and middle-income areas. Yet, treatment guidance for people living with HIV/AIDS (PLWH/A) co-infected with NCC is currently lacking. This study aims to scope the available literature on HIV/AIDS and NCC co-infection, focusing on epidemiology, clinical characteristics, diagnostics and treatment outcomes. Read More

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October 2021

Next-generation sequencing combined with serological tests based pathogen analysis for a neurocysticercosis patient with a 20-year history:a case report.

BMC Neurol 2021 Jun 24;21(1):236. Epub 2021 Jun 24.

Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Background: Neurocysticercosis (NCC) is the most common helminthic infection of the central nervous system (CNS) caused by the larval stage of Taenia solium. Accurate and early diagnosis of NCC remains challenging due to its heterogeneous clinical manifestations, neuroimaging deficits, variable sensitivity, and specificity of serological tests. Next-generation sequencing (NGS)-based pathogen analysis in patient's cerebrospinal fluid (CSF) with NCC infection has recently been reported indicating its diagnostic efficacy. Read More

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Psychiatric Disorders of Neurocysticercosis: Narrative Review.

Neuropsychiatr Dis Treat 2021 25;17:1599-1610. Epub 2021 May 25.

Department of Psychiatry and Psychotherapy III, University of Ulm, Ulm, 89075, Germany.

Neurocysticercosis, the most common type of neuroparasitosis, is a condition in which the central nervous system (CNS) is infested with the pork tapeworm cysticercosis' larvae. Neurocysticercosis is the most widespread parasitic CNS disease worldwide, affecting more than 50 million individuals. As neurocysticercosis is prevalent in developing countries, the growing number of migrants and travelers increases prevalence in developed countries. Read More

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Neurocysticercosis: Current Perspectives on Diagnosis and Management.

Front Vet Sci 2021 10;8:615703. Epub 2021 May 10.

Zhejiang University-University of Edinburgh Institute, Zhejiang University School of Medicine, Zhejiang University, Haining, China.

Porcine cysticercosis, human taeniasis, and (neuro)cysticercosis are endemic in many low- and middle-income countries (LMIC) where they present a significant health burden to affected communities. Neurocysticercosis (NCC) is one of the leading causes of human epilepsy in many hyperendemic regions in Latin America, Asia, and sub-Saharan Africa. The World Health Organization (WHO) reports an estimated 2. Read More

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Diagnostic and management challenges of intraventricular neurocysticercosis presenting in the third trimester of pregnancy: A case report.

Obstet Med 2021 Mar 18;14(1):57-61. Epub 2020 Mar 18.

Department of Obstetrics and Gynaecology, Jawaharlal Institute of Post-graduate Medical Education & Research (JIPMER), Puducherry, India.

The diagnosis of neurocysticercosis in pregnancy is challenging, even in endemic areas, as other neurological conditions with similar manifestations are common. Obstetricians and physicians may be reluctant to do neuroimaging in pregnancy and often the availability is limited in endemic areas. Management of neurocysticercosis depends on the symptomatology. Read More

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Recurrent Neurocysticercosis: Not So Rare.

Neurol India 2021 Mar-Apr;69(2):385-391

Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.

Background: Solitary cysticercus granuloma (SCG) appearing as a single ring-enhancing lesion (SREL) is the most frequently encountered imaging finding in patients of neurocysticercosis (NCC) in India and during follow-up, most of SCGs resolve with or without calcifications. Recurrent SCG have been rarely reported.

Objectives: The aim of our study is to report the incidence of recurrent SCG in a cohort of patients with SCG and postulate the hypothesis. Read More

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Neurocysticercosis Presenting With a New-Onset Seizure: A Case Report.

Cureus 2021 Mar 15;13(3):e13897. Epub 2021 Mar 15.

Internal Medicine/Infectious Disease, Richmond University Medical Center, Staten Island, USA.

Neurocysticercosis (NCC) is a common infection that is found worldwide but is often neglected in the United States (US). This case report aims to illustrate the presentation of the disease, provide information on this globally prevalent pathogen, and shed light on the diagnostic workup and treatment of the infection. We discuss the case of a 31-year-old male patient of Central American origin presenting with a new-onset seizure. Read More

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High frequency of Taenia solium antigen positivity in patients admitted for neurological disorders in the Rural Hospital of Mosango, Democratic Republic of Congo.

BMC Infect Dis 2021 Apr 17;21(1):359. Epub 2021 Apr 17.

Department of Clinical Sciences, Institute of Tropical Medicine, Antwerp, Belgium.

Background: The epidemiology of human cysticercosis and neurocysticercosis, caused by the larval stage of the pork tapeworm Taenia solium, is not well known in the Democratic Republic of Congo (DRC). Within a multicenter etiological and diagnostic study conducted by the NIDIAG consortium ("Better Diagnosis for Neglected Infections") and investigating several challenging syndromes, we consecutively evaluated from 2012 to 2015 all patients older than 5 years presenting with neurological disorders (neurology cohort) and with fever > 7 days (persistent fever cohort) at the rural hospital of Mosango, province of Kwilu, DRC. In both cohorts, etiological diagnosis relied on a systematic set of reference laboratory assays and on pre-established clinical case definitions. Read More

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[Clinical characteristics of neurocysticercosis from a reference hospital of the northern of Peru. 2016-2018].

Rev Chilena Infectol 2020 Dec;37(6):690-693

Hospital Regional Lambayeque, Perú.

Backgound: Neurocysticercosis (NCC) is the most common parasitosis of the central nervous system, and a very important cause of epilepsy.

Aim: To describe the clinical features of patients with NCC attending a high level hospital from Lambayeque during: 2016-2018.

Methods: The medical records of patients with NCC were reviewed, and their information was collected on a data sheet. Read More

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December 2020

Neurocysticercosis in patients with active epilepsy in the tea garden community of Assam, Northeast India.

Sci Rep 2021 04 1;11(1):7433. Epub 2021 Apr 1.

ICMR-Regional Medical Research Centre, N. E. Region, Dibrugarh, Assam, 786001, India.

Neurocysticercosis is a significant cause of epilepsy in the tropics. The present cross-sectional survey was conducted in the socioeconomically backward tea garden community of Assam to gauge the prevalence of neurocysticercosis in patients with active epilepsy and to determine the associated risk factors. In a door to door survey, a total of 1028 individuals from every fifth household of the study Teagarden were enrolled to identify self-reported seizure cases, followed by a neurological examination to confirm the diagnosis of active epilepsy. Read More

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