309 results match your criteria Neurogenic Tumors of the Mediastinum


Primary Intrathoracic Neurogenic Tumors: Clinical, Pathological, and Long-Term Outcomes.

Thorac Cardiovasc Surg 2020 Jul 11. Epub 2020 Jul 11.

Division of Thoracic Surgery, European Institute of Oncology, IRCCS, Milan, Italy.

Background:  Intrathoracic neurogenic tumors (INTs) are uncommon neoplasms arising from nerve tissues. We report our single-center experience in treating these rare INTs.

Methods:  Using a prospective institutional database, clinical, surgical, and pathological records of patients receiving resection of INT between May 1998 and June 2018 were analyzed. Read More

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http://dx.doi.org/10.1055/s-0040-1712499DOI Listing

A diagnostic review of carcinomas and sarcomas of the mediastinum: making the diagnosis on fine-needle aspiration and core needle biopsy specimens.

Semin Diagn Pathol 2020 Jul 16;37(4):187-198. Epub 2020 May 16.

Department of Pathology and Laboratory Medicine, Markey Cancer Center, University of Kentucky, 800 Rose Street, MS 117, Lexington, KY 40536, USA. Electronic address:

The mediastinum is a complex anatomic region that can pose many diagnostic challenges on fine-needle aspiration (FNA) and core needle biopsy (CNB). With the recent technological advancements in EBUS-TBNA and EUS-guided procedures, FNA/CNB is being increasingly utilized to obtain the initial and, in many cases, the only diagnosis. As a result, it is imperative to have an understanding of the pearls and pitfalls associated with both the more common and rarer malignancies that occur at this site. Read More

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http://dx.doi.org/10.1053/j.semdp.2020.04.007DOI Listing

Neurogenic Tumors of the Mediastinum.

Semin Diagn Pathol 2020 Jul 21;37(4):179-186. Epub 2020 May 21.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD.

Neurogenic tumors represent a broad ill-defined category of neoplasms that includes tumors of Schwann cell and/or neuroblastic derivation, as well as neoplasms that typically develop in the central nervous system, but rarely present in ectopic sites including the mediastinum. Neurogenic tumors may occur at many different anatomic sites, but the mediastinum represents a uniquely challenging site given the complex anatomy. Additionally, some of these neoplasms may present with multicentric involvement in the context of genetic syndromes, including NF1, NF2 and schwanomatosis. Read More

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http://dx.doi.org/10.1053/j.semdp.2020.04.004DOI Listing

Mediastinal ganglioneuroma diagnosed by transesophageal endoscopic ultrasound guided fine needle aspiration (EUS-FNA).

Diagn Cytopathol 2020 Aug 12;48(8):769-772. Epub 2020 May 12.

Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota, USA.

Ganglioneuromas are rare benign tumors that arise from the sympathetic nerve fibers and represent the final maturation stage of neuroblast tumors. The most common sites of involvement in the body include posterior mediastinum, followed by retroperitoneum, adrenal gland, and soft tissues of the head and neck. In the mediastinum, this tumor is most frequently located in posterior compartment, together with other neurogenic tumors. Read More

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http://dx.doi.org/10.1002/dc.24445DOI Listing

Mediastinal Hibernoma: A Rare Cause of Chronic Cough.

Cureus 2020 Jan 22;12(1):e6738. Epub 2020 Jan 22.

Internal Medicine, Clinica Medellin Occidente, Medellin, COL.

A hibernoma is an uncommon benign soft tissue tumor composed of brown adipose cells; the mediastinal location as presentation is scarce, with only six cases previously reported. The diagnosis of hibernoma is challenging and must be made based on the clinical, radiographic, and cytologic features. Here we present a 33-year-old woman without any relevant medical history presented for outpatient evaluation of a dry cough persisting for three months, and the X-rays revealed a dense well-defined mass with smooth borders in the left upper posterior mediastinum. Read More

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http://dx.doi.org/10.7759/cureus.6738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034743PMC
January 2020

[Left Paraganglioma in the Posterior Mediastinum].

Kyobu Geka 2019 Dec;72(13):1072-1075

Department of Thoracic Surgery, Hyogo Cancer Center, Akashi, Japan.

A 69-year-old man with hypertension was referred for an abnormal shadow detected on chest computed tomography(CT) at a medical checkup. Enhanced CT showed a highly enhanced posterior mediastinal tumor of 34×27 mm. Magnetic resonance imaging (MRI) revealed a low signal intensity on T1-weighted images and high signal intensity on T2-weighted images. Read More

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December 2019

Distribution of Mediastinal Lesions Across Multi-Institutional, International, Radiology Databases.

J Thorac Oncol 2020 Apr 20;15(4):568-579. Epub 2019 Dec 20.

The Chaim Sheba Medical Center, affiliated with the Tel Aviv University, Tel Aviv, Israel.

Introduction: Mediastinal lesions are uncommon; studies on their distribution are, in general, small and from a single institution. Furthermore, these studies are usually based on pathology or surgical databases and, therefore, miss many lesions that did not undergo biopsy or resection. Our aim was to identify the distribution of lesions in the mediastinum in a large international, multi-institutional cohort. Read More

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http://dx.doi.org/10.1016/j.jtho.2019.12.108DOI Listing

Benign schwannoma of posterior mediastinum accompanied by bloody pleural effusion misdiagnosed as solitary fibrous tumor: A case report.

Caspian J Intern Med 2019 ;10(4):468-471

Department of Pathology, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.

Background: Schwannoma is a peripheral nerve sheath tumor originating from schwann cells. It is the most common neurogenic tumor of the posterior mediastinum. Pleural effusion is a rare presentation of benign schwannoma and it is mainly related to malignant tumors. Read More

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http://dx.doi.org/10.22088/cjim.10.4.468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856921PMC
January 2019

Evaluation of surgical procedures in primary mediastinal cysts and tumors: single-center experience.

Kardiochir Torakochirurgia Pol 2019 Oct 28;16(3):109-113. Epub 2019 Oct 28.

Chest Diseases Clinics, Medicalpark Elazığ Hospital, Elazığ, Turkey.

Aim: In this study, we aimed to evaluate the results of our patients with a primary mediastinal mass and the surgical techniques applied in our clinic retrospectively.

Material And Methods: Between March 2015 and March 2019, the results and treatment protocols of 32 patients with a primary mediastinal mass or cysts who were followed up and treated in our clinic were evaluated retrospectively. Twenty-six patients who underwent surgery for biopsy or resection were included in the study. Read More

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http://dx.doi.org/10.5114/kitp.2019.88597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836631PMC
October 2019

A Missed Diagnosis of Hemangioma Mimicking Neurogenic Tumor in the Posterior Mediastinum.

Ann Thorac Surg 2020 03 7;109(3):e229. Epub 2019 Nov 7.

Lung Cancer Center, West China Hospital of Sichuan University, Chengdu, China. Electronic address:

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http://dx.doi.org/10.1016/j.athoracsur.2019.09.050DOI Listing

Robotic-assisted simultaneous resection of a left-sided thymic neoplasm and a right-sided lower thoracic paravertebral neoplasm via the same ports and two docking steps: a case report.

J Cardiothorac Surg 2019 Oct 29;14(1):182. Epub 2019 Oct 29.

Department of Thoracic Surgery, West China Hospital of Sichuan University, Chengdu, 610041, China.

Background: The authors presented a 63-year old female synchronously complicated with a thymic tumor located at the left-side of the superior mediastinum, and a paravertebral tumor located at the right-side of the lower thorax. Conventional thoracoscopic surgical procedure using rigid instruments to simultaneously resect the two tumors via the same ports might be technically challenging. To our knowledge, the use of a surgical robot allowed the surgeon to perform precise dissection from extreme angles with the characteristic of articulating surgical instruments. Read More

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http://dx.doi.org/10.1186/s13019-019-0989-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6819585PMC
October 2019
1 Read

[Benign primitive schwannoma of the pleura].

Pan Afr Med J 2019 3;33:164. Epub 2019 Jul 3.

Service de Chirurgie Thoracique et Cardio-vasculaire, CHU Mohammed VI, Oujda, Maroc.

Schwannoma is a neurogenic tumor originating from Schwann cells. When considering the thoracic region, it is most commonly found in the mediastinum. It commonly appears as a solitary lesion and pleural involvement is extremely rare. Read More

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http://dx.doi.org/10.11604/pamj.2019.33.164.17625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756821PMC
October 2019
1 Read

A single-institution experience of neurogenic tumors of the mediastinum.

Asian Cardiovasc Thorac Ann 2019 Oct 18;27(8):661-669. Epub 2019 Sep 18.

Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia.

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http://journals.sagepub.com/doi/10.1177/0218492319878575
Publisher Site
http://dx.doi.org/10.1177/0218492319878575DOI Listing
October 2019
11 Reads

[CLINICAL AND DIAGNOSTICS ASPECTES OF BENIGN MEDIASTINAL FORMATIONS IN CHILDREN].

Georgian Med News 2019 Apr(289):55-61

P.L. Shupyk National Medical Academy of Postgraduate Education, Ministry of Healthcare of Ukraine, Department of Thoracic Surgery and Pulmonology, Kiev, Ukraine.

There were more than 730 patients aged 3 months to 18 years with formations of the mediastinum, treated in Pediatric Clinic of Thoracic Surgery NMAPE P. L. Shupyk during the period from 1995 to 2018. Read More

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April 2019
16 Reads

Incidental ancient schwannoma of the posterior mediastinum in a young male: a rare scenario.

BMJ Case Rep 2019 May 10;12(5). Epub 2019 May 10.

Department of Pathology, Sri Ramachandra University Medical College, Chennai, Tamil Nadu, India.

Ancient schwannoma is a distinctive type of schwannoma occurring mostly in the retroperitoneum. The presentation in the posterior mediastinum is rare. The term 'ancient' represents a group of neurogenic tumours showing degenerative changes with marked nuclear atypia. Read More

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http://dx.doi.org/10.1136/bcr-2018-227497DOI Listing
May 2019
5 Reads

Surgical treatment of posterior mediastinal neurogenic tumors.

J Surg Oncol 2019 May 17;119(6):807-813. Epub 2019 Jan 17.

Department of Cardiothoracic Surgery, Huashan Hospital, Fudan University, Shanghai, China.

Background: Posterior mediastinal neurogenic tumors are among the most frequent mediastinal masses in adults. These tumors may be dumbbell shaped, extending into the spinal canal, exclusively paraspinal or apical tumors extending in the cervical region. In this report, we present our experience in the surgical resection of these tumors and discuss the surgical strategies for such tumors. Read More

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http://dx.doi.org/10.1002/jso.25381DOI Listing
May 2019
11 Reads

Angiographic embolization followed by piecemeal resection of giant posterior mediastinal schwannoma: Case report and concise review.

Int J Surg Case Rep 2018 29;53:250-253. Epub 2018 Oct 29.

Department of Surgery, University of Florida, Gainesville, FL, United States. Electronic address:

Introduction: Posterior mediastinal masses present unique diagnostic and therapeutic challenges, particularly when large highly vascularized tumors extend toward or emanate from the spinal cord. The rare nature of these tumors precludes the development of standardized management algorithms, underscoring the importance of case reports.

Presentation Of Case: A 57 year old female presented with exertional dyspnea and right chest pressure. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.10.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234618PMC
October 2018
4 Reads

Surgical treatment of thoracic dumbbell tumors.

Eur J Surg Oncol 2019 05 28;45(5):851-856. Epub 2018 Oct 28.

Department of Cardiothoracic Surgery, Huashan Hospital, Fudan University, Shanghai, PR China. Electronic address:

Background: Thoracic dumbbell tumors are uncommon neoplasms arising from neurogenic elements of the posterior mediastinum. Surgical removal of these tumors with mediastinal, neuroforaminal and intraspinal components can often be challenging. The purpose of this study is to present our experience of single-stage removal of dumbbell tumors of the posterior mediastinum and to discuss the surgical strategies for such tumors. Read More

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http://dx.doi.org/10.1016/j.ejso.2018.10.536DOI Listing
May 2019
5 Reads

Surgical resection of extramedullary haematopoiesis in the posterior mediastinum.

Respirol Case Rep 2018 Oct 6;6(7):e00358. Epub 2018 Sep 6.

Department of Surgery Kurume University Fukuoka Japan.

Extramedullary haematopoiesis is a rare disease that is usually associated with haematologic disorders such as thalassemia, myelodysplastic syndrome, and hereditary spherocytosis. It frequently occurs in the liver, spleen, and lymph nodes. Rarely, it occurs in the posterior mediastinum. Read More

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http://dx.doi.org/10.1002/rcr2.358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127221PMC
October 2018
17 Reads

Mediastinal myelolipoma/extramedullary hematopoiesis presenting as a mass: rare differential diagnosis among mediastinal tumors.

Int J Clin Exp Pathol 2018 1;11(5):2714-2720. Epub 2018 May 1.

Department of Pathology, West China Hospital, Sichuan University Chengdu 610041, Sichuan, China.

Objectives: Mediastinal myelolipoma/extramedullary hematopoiesis presenting as a mass is infrequent and can lead to misdiagnosis. Here we describe a large series aiming to illustrate the clinicopathologic features.

Methods: We retrospectively searched mediastinal tumors and myelolipoma diagnosed at the Department of Pathology, West China Hospital from 2010 to 2015 and collected 14 mediastinal myelolipoma/extramedullary hematopoiesis cases presenting as an encapsulated mass among 1324 mediastinal mass diseases and 252 myelolipomas. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958304PMC

Middle mediastinal schwannoma concealed by asthma and GORD.

BMJ Case Rep 2018 Mar 13;2018. Epub 2018 Mar 13.

Department of Surgery, University of Santo Tomas Hospital, Manila, Philippines.

Neurogenic tumours of the mediastinum in adults occur most often at the posterior mediastinum, majority of which are benign of nerve sheath in origin. A 72-year-old woman, known asthmatic, presented with chronic symptoms of hoarseness, dysphagia, chest heaviness, easy fatigability, cough, epigastric pain, feeling of abdominal fullness and choking with food intake and at a supine position. Treated for other disorders, routine chest X-ray incidentally found a homogenous convex radiodensity at the right paratracheal area; mass which was also observed with CT and 18F-fludeoxyglucose-positron emission tomography/CT scan studies. Read More

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http://dx.doi.org/10.1136/bcr-2017-223795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878299PMC
March 2018
14 Reads

Extragonadal germ cell tumor of the posterior mediastinum in a child complicated with spinal cord compression: a case report.

BMC Pediatr 2018 03 5;18(1):97. Epub 2018 Mar 5.

Department of Pediatrics, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.

Background: Germ cell tumors (GCTs) in children are rare neoplasms with diverse pathological findings according to the site and age of presentation. The most common symptoms in children with mediastinal GCTs, which are nonspecific, are dyspnea, chest pain, cough, hemoptysis, vena cava occlusion syndrome, and fatigue/weakness. Because of these nonspecific symptoms, it is difficult to suspect a mediastinal mass. Read More

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http://dx.doi.org/10.1186/s12887-018-1070-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838956PMC
March 2018
34 Reads

A Rare Case of Primary Intrapulmonary Neurilemmoma Diagnosed in a 43-Year-Old Asymptomatic Man with a Well-defined Intrapulmonary Mass.

Front Oncol 2018 30;8:11. Epub 2018 Jan 30.

5th Pulmonology Department, Athens Chest Hospital "Sotiria", Athens, Greece.

Neurilemmoma (NL), also termed schwannoma, presents as a well-circumscribed and encapsulated mass in the human body and is almost always solitary. CT scan of a patient with NL shows a round, ovoid, or lobulated well-demarcated solid mass of soft tissue density. Primary intrathoracic neurogenic tumors location varies. Read More

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http://dx.doi.org/10.3389/fonc.2018.00011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797600PMC
January 2018
21 Reads

Extramedullary Hematopoiesis Mimicking Mediastinal Tumor in a Patient with Hereditary Spherocytosis: Case report.

Int J Surg Case Rep 2017 27;41:223-225. Epub 2017 Oct 27.

Department of Thoracic and Cardiovascular Surgery, Konkuk University Medical Center, Seoul, Republic of Korea. Electronic address:

Introduction: Extramedullary hematopoiesis (EMH) is a rare disorder, defined as the appearance of hematopoietic elements outside the bone marrow or peripheral blood. The exact mechanism of this development is still unknown. We herein report a case of intrathoracic EMH, manifesting as a posterior mediastinal tumor in a patient with hereditary spherocytosis. Read More

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http://dx.doi.org/10.1016/j.ijscr.2017.10.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686225PMC
October 2017
14 Reads

Video-assisted and minimally-invasive open chest surgery for the treatment of mediastinal tumors and masses.

J Vis Surg 2017 8;3:25. Epub 2017 Mar 8.

Department of Surgery, Laval University, Quebec City, Quebec, Canada.

This article reviews the anatomy of the mediastinum as well as indications, limitations, techniques, and results of video-assisted thoracic surgery (VATS) and other minimally-invasive open-chest surgery approaches currently used for the surgical management of mediastinal tumors and masses. It is written by two surgeons with vastly different backgrounds and thoracic surgical experience. One of them is young and very familiar with VATS approaches and technologies while the other is a senior surgeon relatively unfamiliar with minimally-invasive techniques. Read More

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http://dx.doi.org/10.21037/jovs.2017.01.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638199PMC
March 2017
16 Reads

Mediastinal lesions across the age spectrum: a clinicopathological comparison between pediatric and adult patients.

Oncotarget 2017 Aug 18;8(35):59845-59853. Epub 2017 Apr 18.

Department of Pathology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

The objective of this study was to identify the differences in histopathological distribution and clinical features of mediastinal lesions (MLs) across the age spectrum in Chinese series of patients and to compare with the available literature. A total of 409 cases of MLs, including 137 pediatric and 272 adult patients from a single institution, was reviewed and categorized into groups according to age. Among the 409 cases, the age showed a bimodal distribution with an increased incidence of MLs among (< 10 year) and (60-< 70 year) age groups. Read More

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http://www.oncotarget.com/fulltext/17201
Publisher Site
http://dx.doi.org/10.18632/oncotarget.17201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601783PMC
August 2017
32 Reads
6.360 Impact Factor

An analysis of clinical characteristics and patient outcomes in primary mediastinal sarcomas.

Expert Rev Anticancer Ther 2017 11 14;17(11):1071-1076. Epub 2017 Sep 14.

a Clinical Oncology Department, Faculty of Medicine , Ain Shams University , Cairo , Egypt.

Background: Published data concerning primary mediastinal sarcomas are limited to small-sized retrospective series.  This study reviewed the clinical outcomes of these cases from the SEER (surveillance, epidemiology and end results) database.

Methods: Primary mediastinal sarcomas (1988 - 2013) were assembled from the SEER database. Read More

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http://dx.doi.org/10.1080/14737140.2017.1378576DOI Listing
November 2017
17 Reads

An Unusual Schwannoma.

J Assoc Physicians India 2017 Jun;65(6):92-94

Department of Pulmonary Medicine, TN Medical College, BYL Nair Hospital, Mumbai, Maharashtra.

Mediastinal masses are commonly encountered and have multiple differentials. Although histopathological examination is gold standard, the location of the mass narrows the diagnosis. While thyroid, thymus, germ cell tumour or lymph node related masses are common in superior mediastinum, vascular or pleuro-pericardial masses are seen in middle mediastinum. Read More

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June 2017
17 Reads

Verner-Morrison syndrome. Literature review.

Rom J Morphol Embryol 2017 ;58(2):371-376

Department of Pediatric Surgery, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania; Department of Neonatology, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania;

Chronic diarrhea in infants is a common condition for addressability to pediatric gastroenterologists. The causes are multiple and the delay in reaching the final diagnosis can lead to complications in the general condition of the child. The purpose of this review is to present the bio-clinical and histogenetic particularities of a rare clinical entity, characterized by tumoral causes of chronic diarrhea. Read More

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April 2018
72 Reads

An Involuntary and Unexpected Treatment of Nutcracker Esophagus.

Ann Thorac Surg 2017 Jun;103(6):e545-e547

Department of Thoracic Surgery, North Hospital, Aix-Marseille University and Assistance Publique-Hôpitaux de Marseille, Marseille, France. Electronic address:

A 76-year-old woman complained of painful dysphagia and loss of weight. Esophagoscopy results were negative, whereas computed tomography (CT) disclosed a 25-mm mediastinal tumor without a connection to the esophagus. A diagnosis of nutcracker esophagus was made on high-resolution esophageal manometry. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2016.12.053DOI Listing
June 2017
59 Reads

Robotic paravertebral schwannoma resection at extreme locations of the thoracic cavity.

Neurosurg Focus 2017 May;42(5):E17

Thoracic Surgery Section, Department of Surgery, University of Miami Miller School of Medicine, Miami, Florida.

Solitary paravertebral schwannomas in the thoracic spine and lacking an intraspinal component are uncommon. These benign nerve sheath tumors are typically treated using complete resection with an excellent outcome. Resection of these tumors is achieved by an anterior approach via open thoracotomy or minimally invasive thoracoscopy, by a posterior approach via laminectomy, or by a combination of both approaches. Read More

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http://dx.doi.org/10.3171/2017.2.FOCUS16551DOI Listing
May 2017
57 Reads

[True thymic hyperplasia : Differential diagnosis of thymic mass lesions in neonates and children].

Pathologe 2017 Jul;38(4):286-293

Pathologisches Institut, Universitätsmedizin Mannheim, Universität Heidelberg, Theodor Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland.

Reactive and neoplastic thymic pathologies are the main considerations in the case of masses in the anterior and middle part of the mediastinum, while neurogenic tumors are predominant in the posterior mediastinum (which are not dealt with here). In neonates and infants, the commonest pathologies in the anterior mediastinum comprise germ cell tumors (mainly teratomas), congenital thymic cysts and true thymic hyperplasia (TTH). In toddlers, teratomas, yolk sac tumors and cysts predominate. Read More

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http://dx.doi.org/10.1007/s00292-017-0283-zDOI Listing
July 2017
5 Reads

A Mullerian Cyst Resected From the Posterior Mediastinum.

J La State Med Soc 2017 Mar-Apr;169(2):43-47. Epub 2017 Apr 15.

Cardiothoracic and Vascular Surgery at LSUHSC in Shreveport, LA.

Differential diagnoses of mediastinal masses are often based on the anatomic locations. Traditionally the posterior mediastinum has been home to esophageal and neurogenic cysts, but a new entity has been found to be prevalent since its initial report in 2005: the Müllerian cyst. We present a 49-year-old with history of cough who was found to have such a mass. Read More

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September 2017
18 Reads

Schwannoma of the Recurrent Laryngeal Nerve: A Rare Entity.

Innovations (Phila) 2017 Jan/Feb;12(1):64-66

From the Departments of *Cardiothoracic Surgery, †Pulmonology, and ‡Pathology, University Medical Central Utrecht, Utrecht, The Netherlands.

Neurogenic tumors are the most common posterior mediastinal tumors in adults. Schwannomas originating from the recurrent laryngeal nerve are rare. The present study describes a 46-year-old man with a tumor in the left superior mediastinum. Read More

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http://dx.doi.org/10.1097/IMI.0000000000000334DOI Listing
March 2017
13 Reads

Intrathoracic neurogenic tumor with malignant transition-20 years operation experience in a medical center of China.

Neurosci Lett 2017 01 4;637:195-200. Epub 2016 Nov 4.

Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Medical School of Tongji University, Zhengmin Road 507, Shanghai, 200433, China. Electronic address:

Objective: Malignant peripheral neurogenic tumor is always found in large peripheral nerve of the extremities, however, benign peripheral neurogenic tumors of chest is an uncommon disorder, furthermore, malignant transition is even rare. So far, few cases have been reported. We studied 45 neurogenic thoracic tumors patients with malignant transition. Read More

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http://dx.doi.org/10.1016/j.neulet.2016.11.010DOI Listing
January 2017
8 Reads

[Neurogenic mediastinal tumors in adults].

Rev Pneumol Clin 2016 Oct 24;72(5):310-315. Epub 2016 Aug 24.

Service de chirurgie thoracique, CHU Hassan II, BP 1893, km 2200, route de Sidi Hrazem, 3000 Fes Maroc.

Introduction: Neurogenic mediastinal tumors are tumors develop at the expense of peripheral nerve elements of the mediastinum, the sympathetic nervous tissue and paraganglia. The series that we propose has the distinction of a high frequency of malignant forms and a wealth of clinical symptomatology.

Methods: This is a retrospective study of 9 patients collected over a period of 6 years. Read More

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http://dx.doi.org/10.1016/j.pneumo.2016.05.002DOI Listing
October 2016
5 Reads

Giant mediastinal schwannoma located in the lower right side of the chest.

Authors:
Y Wu J Zhang Y Chai

Niger J Clin Pract 2016 Sep-Oct;19(5):678-80

Department of Thoracic Surgery, School of Medicine, Second Affiliated Hospital, Zhejiang University, Hangzhou, China.

Schwannoma is a type of neurogenic tumor usually found in the posterior mediastinum. Most schwannomas range in size from 2 to 3 cm; some can exceed 10 cm. We herein report a case of a rare, large mediastinal schwannoma whose size is 20 cm × 15 cm × 12 cm, which has rarely reported before. Read More

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http://dx.doi.org/10.4103/1119-3077.188701DOI Listing
January 2018
8 Reads

[Transmanubrial Osteomuscular-sparing Approach for Resection of Superior Mediastinal Schwannoma].

Kyobu Geka 2016 Aug;69(9):760-3

Department of Cardiovascular and Thoracic Surgery, Hokkaido University, Graduate School of Medicine, Sapporo, Japan.

Various approaches can be applied to resect superior mediastinal tumor. It is important to choose the procedure according to the location, size, and characteristics of the tumor in order to perform safe procedure surgery because of distinctive anatomy of this site. We hereby report on a case of Schwannoma of the superior mediastinum resected by the transmanubrial approach. Read More

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August 2016
22 Reads

[The resection of the huge mediastinal schwannoma by the jugulal approach: one case report].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2016 Feb;30(4):329-30

Neurogenic tumors located in the posterior mediastinum, generally require surgery which be confronted with greater risk,therefore, to design the best surgical approach and surgical methods is essential. A 67-year-old female patient had pharyngeal foreign body sensation and dysphagia. Thyroid ultrasound showed the right thyroid had a little nodule, and the left thyroid had a hypoechoic lumps. Read More

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February 2016
11 Reads

Imaging of Thoracic Neurogenic Tumors.

AJR Am J Roentgenol 2016 Sep 24;207(3):552-61. Epub 2016 Jun 24.

6 Department of Radiology and Radiological Sciences, Uniformed Services University of the Health Sciences, Bethesda, MD.

Objective: Thoracic neurogenic neoplasms may be a diagnostic challenge both clinically and radiologically, ranging from benign, incidentally discovered tumors to aggressive, symptomatic malignancies. These tumors may originate from any nervous structure within the chest and are derived from cells of the nerve sheath, autonomic ganglia, or paraganglia. The nervous anatomy of the thorax is complex, and neurogenic tumors may be found in any mediastinal compartment or in the chest wall. Read More

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http://dx.doi.org/10.2214/AJR.16.16018DOI Listing
September 2016
31 Reads

Giant Benign Mediastinal Masses Extending into the Pleural Cavity.

Surg J (N Y) 2016 Apr 10;2(2):e46-e50. Epub 2016 Jun 10.

Department of Thoracic Surgery, Medical Faculty, Selçuk University, Konya, Turkey.

 The aim of the study was to evaluate the results of surgery to remove huge mediastinal masses and their pathology. Surgical resection was chosen for accurate diagnosis and treatment of the huge mediastinal masses extending into the pleural cavity.  Records were reviewed for eight patients who had the diagnosis of huge benign mediastinal masses and who underwent operation; details of the patients and operations were recorded. Read More

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http://dx.doi.org/10.1055/s-0036-1584519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553481PMC
April 2016
8 Reads

Dumbbell Shaped Schwannoma of the Lateral Chest Wall masquandering as a soft tissue sarcoma.

Indian J Surg Oncol 2015 Sep 25;6(3):307-10. Epub 2015 Jun 25.

Cancer Institute (WIA), 38, Sardar Patel Rd, Adyar, Chennai, 600036 India.

Schwannomas are benign, slow growing nerve sheath tumours of Schwann cell origin. They predominantly are known to involve the head, neck and the flexor surfaces of the extremities, retroperitoneum and the posterior spinal roots. The chest wall is a relatively uncommon location for a schwannoma, the vast majority of which are intra-thoracic, which are usually located in the posterior mediastinum and bulge into the thoracic cavity. Read More

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http://dx.doi.org/10.1007/s13193-015-0435-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856675PMC
September 2015
65 Reads

Gynaecological Perspective of Schwannoma: A Rare Pelvic Tumour.

J Clin Diagn Res 2016 Apr 1;10(4):QD03-5. Epub 2016 Apr 1.

Professor, Department of Pathology, Saveetha Medical College and Hospital , Chennai, India .

Schwannomas are benign tumours that arise from Schwann cells of nerve fibres. They commonly occur in the head, neck, mediastinum and extremities but pelvic occurrence is rare. We report a rare case of retroperitoneal tumour with Gynaec presentation. Read More

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http://dx.doi.org/10.7860/JCDR/2016/16301.7587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866198PMC
April 2016
9 Reads

Symptomatic pericardial schwannoma treated with video-assisted thoracic surgery: a case report.

J Thorac Dis 2016 May;8(5):E349-52

1 Division of Thoracic Surgery, Department of Surgery, 2 Department of Pathology, 3 Division of Pulmonary and Critical Care, Department of Internal Medicine, Tri-Service General Hospital, Taipei, Taiwan.

Intrathoracic schwannomas are neurogenic tumors derived from the Schwann cells of the nerve sheath, most often seen in the posterior mediastinum with anatomical correlations to nerves. Although they are typically benign, a malignant transformation can occur, and thoracotomy instead of video-assisted thoracoscopic surgery (VATS) is required to achieve a complete resection. Only a few cases of pericardial schwannoma have been reported so far. Read More

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http://dx.doi.org/10.21037/jtd.2016.03.40DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842797PMC
May 2016
12 Reads

[Schwannoma in the Middle Mediastinum Originating from the Vagal Nerve;Report of a Case].

Kyobu Geka 2016 Mar;69(3):236-9

Department of Thoracic Surgery, Higashiosaka Municipal Hospital, Higashiosaka, Japan.

A 44-year-old woman was referred to our department with a mediastinal tumor detected by computed tomography performed as a preoperative examination for cervical cancer. There was a 32 mm solid mass in the area surrounded by the descending thoracic aorta, esophagus, left atrium, left lower lobe, and mediastinal pleura. The tumor was removed thoracoscopically. Read More

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March 2016
17 Reads

A case of schwannoma of the mesoesophagus displaced from the left to the right of the posterior mediastinum.

Gen Thorac Cardiovasc Surg 2017 Jan 19;65(1):59-62. Epub 2016 Mar 19.

Department of Thoracic Surgery, Osaka Medical College Hospital, 2-7 Daigaku-cho, Takatsuki, 569-8686, Japan.

Although schwannomas are the most common neurogenic tumors found in the thorax, schwannomas of the mesoesophagus are extremely rare. We report a case of an 80-year-old man having a tumor in contact with the esophagus in the left posterior mediastinum. A preoperative follow-up computed tomography scan showed tumor displacement from the left to the right of the posterior mediastinum. Read More

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http://dx.doi.org/10.1007/s11748-016-0641-4DOI Listing
January 2017
13 Reads

Malignant Schwannoma of the Esophagus: A Rare Case Report.

Korean J Thorac Cardiovasc Surg 2016 Feb 5;49(1):63-6. Epub 2016 Feb 5.

Department of Radiodiagnosis, All India Institute of Medical Sciences.

Neurogenic tumors are the most prevalent tumors of the mediastinum, and schwannomas are the most common type of neurogenic tumor. Primary neurogenic neoplasm of the esophagus is uncommon and malignant schwannoma of the esophagus is extremely rare. We report a case of a 27-year-old female presenting with dysphagia and palpitations who was found to have a lobulated tumor in the mediastinum that was compressing the esophageal lumen. Read More

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http://dx.doi.org/10.5090/kjtcs.2016.49.1.63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757402PMC
February 2016
6 Reads

Intrathoracic Malignant Peripheral Nerve Sheath Tumor: Histopathological and Immunohistochemical Features.

Iran J Pathol 2015 ;10(1):74-8

Department of Pathology, Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.

Malignant peripheral nerve sheath tumor (MPNST) is a rare nerve sheath tumor derived from Schwann cells or pleuripotent cells of neural crest. Neurogenic tumors make about 10-20% of all mediastinal tumors. Incidence of MPNST is 0. Read More

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http://jco.ascopubs.org/content/26/13/2216.full.pdf
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539789PMC
October 2015
12 Reads

[Mediastinal Hemangioma with Literature Review;Report of a Case].

Kyobu Geka 2015 Jul;68(7):556-9

Department of Surgery and Oncology, Kyushu University, Fukuoka, Japan.

A 58-year-old woman visited a local physician for evaluation of collagen disease and screening computed tomography (CT) showed a posterior mediastinal tumor. After referral to our hospital, CT and magnetic resonance imaging (MRI) showed a mass, approximately 2 cm in diameter, located on the right of the 1st thoracic vertebra. Since a neurogenic tumor was suspected, thoracoscopic excision was performed. Read More

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July 2015
9 Reads