292 results match your criteria Neurogenic Tumors of the Mediastinum


Surgical treatment of posterior mediastinal neurogenic tumors.

J Surg Oncol 2019 May 17;119(6):807-813. Epub 2019 Jan 17.

Department of Cardiothoracic Surgery, Huashan Hospital, Fudan University, Shanghai, China.

Background: Posterior mediastinal neurogenic tumors are among the most frequent mediastinal masses in adults. These tumors may be dumbbell shaped, extending into the spinal canal, exclusively paraspinal or apical tumors extending in the cervical region. In this report, we present our experience in the surgical resection of these tumors and discuss the surgical strategies for such tumors. Read More

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http://dx.doi.org/10.1002/jso.25381DOI Listing
May 2019
5 Reads

Angiographic embolization followed by piecemeal resection of giant posterior mediastinal schwannoma: Case report and concise review.

Int J Surg Case Rep 2018 29;53:250-253. Epub 2018 Oct 29.

Department of Surgery, University of Florida, Gainesville, FL, United States. Electronic address:

Introduction: Posterior mediastinal masses present unique diagnostic and therapeutic challenges, particularly when large highly vascularized tumors extend toward or emanate from the spinal cord. The rare nature of these tumors precludes the development of standardized management algorithms, underscoring the importance of case reports.

Presentation Of Case: A 57 year old female presented with exertional dyspnea and right chest pressure. Read More

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http://dx.doi.org/10.1016/j.ijscr.2018.10.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234618PMC
October 2018
1 Read

Surgical treatment of thoracic dumbbell tumors.

Eur J Surg Oncol 2019 May 28;45(5):851-856. Epub 2018 Oct 28.

Department of Cardiothoracic Surgery, Huashan Hospital, Fudan University, Shanghai, PR China. Electronic address:

Background: Thoracic dumbbell tumors are uncommon neoplasms arising from neurogenic elements of the posterior mediastinum. Surgical removal of these tumors with mediastinal, neuroforaminal and intraspinal components can often be challenging. The purpose of this study is to present our experience of single-stage removal of dumbbell tumors of the posterior mediastinum and to discuss the surgical strategies for such tumors. Read More

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http://dx.doi.org/10.1016/j.ejso.2018.10.536DOI Listing
May 2019
2 Reads

Surgical resection of extramedullary haematopoiesis in the posterior mediastinum.

Respirol Case Rep 2018 Oct 6;6(7):e00358. Epub 2018 Sep 6.

Department of Surgery Kurume University Fukuoka Japan.

Extramedullary haematopoiesis is a rare disease that is usually associated with haematologic disorders such as thalassemia, myelodysplastic syndrome, and hereditary spherocytosis. It frequently occurs in the liver, spleen, and lymph nodes. Rarely, it occurs in the posterior mediastinum. Read More

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http://dx.doi.org/10.1002/rcr2.358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127221PMC
October 2018
5 Reads

Middle mediastinal schwannoma concealed by asthma and GORD.

BMJ Case Rep 2018 Mar 13;2018. Epub 2018 Mar 13.

Department of Surgery, University of Santo Tomas Hospital, Manila, Philippines.

Neurogenic tumours of the mediastinum in adults occur most often at the posterior mediastinum, majority of which are benign of nerve sheath in origin. A 72-year-old woman, known asthmatic, presented with chronic symptoms of hoarseness, dysphagia, chest heaviness, easy fatigability, cough, epigastric pain, feeling of abdominal fullness and choking with food intake and at a supine position. Treated for other disorders, routine chest X-ray incidentally found a homogenous convex radiodensity at the right paratracheal area; mass which was also observed with CT and 18F-fludeoxyglucose-positron emission tomography/CT scan studies. Read More

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http://dx.doi.org/10.1136/bcr-2017-223795DOI Listing
March 2018
6 Reads

Extragonadal germ cell tumor of the posterior mediastinum in a child complicated with spinal cord compression: a case report.

BMC Pediatr 2018 03 5;18(1):97. Epub 2018 Mar 5.

Department of Pediatrics, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.

Background: Germ cell tumors (GCTs) in children are rare neoplasms with diverse pathological findings according to the site and age of presentation. The most common symptoms in children with mediastinal GCTs, which are nonspecific, are dyspnea, chest pain, cough, hemoptysis, vena cava occlusion syndrome, and fatigue/weakness. Because of these nonspecific symptoms, it is difficult to suspect a mediastinal mass. Read More

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http://dx.doi.org/10.1186/s12887-018-1070-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838956PMC
March 2018
21 Reads

A Rare Case of Primary Intrapulmonary Neurilemmoma Diagnosed in a 43-Year-Old Asymptomatic Man with a Well-defined Intrapulmonary Mass.

Front Oncol 2018 30;8:11. Epub 2018 Jan 30.

5th Pulmonology Department, Athens Chest Hospital "Sotiria", Athens, Greece.

Neurilemmoma (NL), also termed schwannoma, presents as a well-circumscribed and encapsulated mass in the human body and is almost always solitary. CT scan of a patient with NL shows a round, ovoid, or lobulated well-demarcated solid mass of soft tissue density. Primary intrathoracic neurogenic tumors location varies. Read More

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http://dx.doi.org/10.3389/fonc.2018.00011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5797600PMC
January 2018
15 Reads

Extramedullary Hematopoiesis Mimicking Mediastinal Tumor in a Patient with Hereditary Spherocytosis: Case report.

Int J Surg Case Rep 2017 27;41:223-225. Epub 2017 Oct 27.

Department of Thoracic and Cardiovascular Surgery, Konkuk University Medical Center, Seoul, Republic of Korea. Electronic address:

Introduction: Extramedullary hematopoiesis (EMH) is a rare disorder, defined as the appearance of hematopoietic elements outside the bone marrow or peripheral blood. The exact mechanism of this development is still unknown. We herein report a case of intrathoracic EMH, manifesting as a posterior mediastinal tumor in a patient with hereditary spherocytosis. Read More

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http://dx.doi.org/10.1016/j.ijscr.2017.10.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686225PMC
October 2017
8 Reads

Video-assisted and minimally-invasive open chest surgery for the treatment of mediastinal tumors and masses.

J Vis Surg 2017 8;3:25. Epub 2017 Mar 8.

Department of Surgery, Laval University, Quebec City, Quebec, Canada.

This article reviews the anatomy of the mediastinum as well as indications, limitations, techniques, and results of video-assisted thoracic surgery (VATS) and other minimally-invasive open-chest surgery approaches currently used for the surgical management of mediastinal tumors and masses. It is written by two surgeons with vastly different backgrounds and thoracic surgical experience. One of them is young and very familiar with VATS approaches and technologies while the other is a senior surgeon relatively unfamiliar with minimally-invasive techniques. Read More

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http://dx.doi.org/10.21037/jovs.2017.01.01DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5638199PMC
March 2017
7 Reads

Mediastinal lesions across the age spectrum: a clinicopathological comparison between pediatric and adult patients.

Oncotarget 2017 Aug 18;8(35):59845-59853. Epub 2017 Apr 18.

Department of Pathology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.

The objective of this study was to identify the differences in histopathological distribution and clinical features of mediastinal lesions (MLs) across the age spectrum in Chinese series of patients and to compare with the available literature. A total of 409 cases of MLs, including 137 pediatric and 272 adult patients from a single institution, was reviewed and categorized into groups according to age. Among the 409 cases, the age showed a bimodal distribution with an increased incidence of MLs among (< 10 year) and (60-< 70 year) age groups. Read More

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http://www.oncotarget.com/fulltext/17201
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http://dx.doi.org/10.18632/oncotarget.17201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5601783PMC
August 2017
22 Reads
6.360 Impact Factor

An analysis of clinical characteristics and patient outcomes in primary mediastinal sarcomas.

Expert Rev Anticancer Ther 2017 11 14;17(11):1071-1076. Epub 2017 Sep 14.

a Clinical Oncology Department, Faculty of Medicine , Ain Shams University , Cairo , Egypt.

Background: Published data concerning primary mediastinal sarcomas are limited to small-sized retrospective series.  This study reviewed the clinical outcomes of these cases from the SEER (surveillance, epidemiology and end results) database.

Methods: Primary mediastinal sarcomas (1988 - 2013) were assembled from the SEER database. Read More

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http://dx.doi.org/10.1080/14737140.2017.1378576DOI Listing
November 2017
7 Reads

An Unusual Schwannoma.

J Assoc Physicians India 2017 Jun;65(6):92-94

Department of Pulmonary Medicine, TN Medical College, BYL Nair Hospital, Mumbai, Maharashtra.

Mediastinal masses are commonly encountered and have multiple differentials. Although histopathological examination is gold standard, the location of the mass narrows the diagnosis. While thyroid, thymus, germ cell tumour or lymph node related masses are common in superior mediastinum, vascular or pleuro-pericardial masses are seen in middle mediastinum. Read More

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June 2017
7 Reads

Verner-Morrison syndrome. Literature review.

Rom J Morphol Embryol 2017 ;58(2):371-376

Department of Pediatric Surgery, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania; Department of Neonatology, "Victor Babes" University of Medicine and Pharmacy, Timisoara, Romania;

Chronic diarrhea in infants is a common condition for addressability to pediatric gastroenterologists. The causes are multiple and the delay in reaching the final diagnosis can lead to complications in the general condition of the child. The purpose of this review is to present the bio-clinical and histogenetic particularities of a rare clinical entity, characterized by tumoral causes of chronic diarrhea. Read More

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April 2018
38 Reads

An Involuntary and Unexpected Treatment of Nutcracker Esophagus.

Ann Thorac Surg 2017 Jun;103(6):e545-e547

Department of Thoracic Surgery, North Hospital, Aix-Marseille University and Assistance Publique-Hôpitaux de Marseille, Marseille, France. Electronic address:

A 76-year-old woman complained of painful dysphagia and loss of weight. Esophagoscopy results were negative, whereas computed tomography (CT) disclosed a 25-mm mediastinal tumor without a connection to the esophagus. A diagnosis of nutcracker esophagus was made on high-resolution esophageal manometry. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2016.12.053DOI Listing
June 2017
33 Reads

Robotic paravertebral schwannoma resection at extreme locations of the thoracic cavity.

Neurosurg Focus 2017 May;42(5):E17

Thoracic Surgery Section, Department of Surgery, University of Miami Miller School of Medicine, Miami, Florida.

Solitary paravertebral schwannomas in the thoracic spine and lacking an intraspinal component are uncommon. These benign nerve sheath tumors are typically treated using complete resection with an excellent outcome. Resection of these tumors is achieved by an anterior approach via open thoracotomy or minimally invasive thoracoscopy, by a posterior approach via laminectomy, or by a combination of both approaches. Read More

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http://dx.doi.org/10.3171/2017.2.FOCUS16551DOI Listing
May 2017
30 Reads

[True thymic hyperplasia : Differential diagnosis of thymic mass lesions in neonates and children].

Pathologe 2017 Jul;38(4):286-293

Pathologisches Institut, Universitätsmedizin Mannheim, Universität Heidelberg, Theodor Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland.

Reactive and neoplastic thymic pathologies are the main considerations in the case of masses in the anterior and middle part of the mediastinum, while neurogenic tumors are predominant in the posterior mediastinum (which are not dealt with here). In neonates and infants, the commonest pathologies in the anterior mediastinum comprise germ cell tumors (mainly teratomas), congenital thymic cysts and true thymic hyperplasia (TTH). In toddlers, teratomas, yolk sac tumors and cysts predominate. Read More

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http://dx.doi.org/10.1007/s00292-017-0283-zDOI Listing
July 2017
1 Read

A Mullerian Cyst Resected From the Posterior Mediastinum.

J La State Med Soc 2017 Mar-Apr;169(2):43-47. Epub 2017 Apr 15.

Cardiothoracic and Vascular Surgery at LSUHSC in Shreveport, LA.

Differential diagnoses of mediastinal masses are often based on the anatomic locations. Traditionally the posterior mediastinum has been home to esophageal and neurogenic cysts, but a new entity has been found to be prevalent since its initial report in 2005: the Müllerian cyst. We present a 49-year-old with history of cough who was found to have such a mass. Read More

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September 2017
9 Reads

Schwannoma of the Recurrent Laryngeal Nerve: A Rare Entity.

Innovations (Phila) 2017 Jan/Feb;12(1):64-66

From the Departments of *Cardiothoracic Surgery, †Pulmonology, and ‡Pathology, University Medical Central Utrecht, Utrecht, The Netherlands.

Neurogenic tumors are the most common posterior mediastinal tumors in adults. Schwannomas originating from the recurrent laryngeal nerve are rare. The present study describes a 46-year-old man with a tumor in the left superior mediastinum. Read More

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http://dx.doi.org/10.1097/IMI.0000000000000334DOI Listing
March 2017
3 Reads

Intrathoracic neurogenic tumor with malignant transition-20 years operation experience in a medical center of China.

Neurosci Lett 2017 01 4;637:195-200. Epub 2016 Nov 4.

Department of Thoracic Surgery, Shanghai Pulmonary Hospital, Medical School of Tongji University, Zhengmin Road 507, Shanghai, 200433, China. Electronic address:

Objective: Malignant peripheral neurogenic tumor is always found in large peripheral nerve of the extremities, however, benign peripheral neurogenic tumors of chest is an uncommon disorder, furthermore, malignant transition is even rare. So far, few cases have been reported. We studied 45 neurogenic thoracic tumors patients with malignant transition. Read More

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http://dx.doi.org/10.1016/j.neulet.2016.11.010DOI Listing
January 2017
4 Reads

[Neurogenic mediastinal tumors in adults].

Rev Pneumol Clin 2016 Oct 24;72(5):310-315. Epub 2016 Aug 24.

Service de chirurgie thoracique, CHU Hassan II, BP 1893, km 2200, route de Sidi Hrazem, 3000 Fes Maroc.

Introduction: Neurogenic mediastinal tumors are tumors develop at the expense of peripheral nerve elements of the mediastinum, the sympathetic nervous tissue and paraganglia. The series that we propose has the distinction of a high frequency of malignant forms and a wealth of clinical symptomatology.

Methods: This is a retrospective study of 9 patients collected over a period of 6 years. Read More

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http://dx.doi.org/10.1016/j.pneumo.2016.05.002DOI Listing
October 2016
2 Reads

Giant mediastinal schwannoma located in the lower right side of the chest.

Authors:
Y Wu J Zhang Y Chai

Niger J Clin Pract 2016 Sep-Oct;19(5):678-80

Department of Thoracic Surgery, School of Medicine, Second Affiliated Hospital, Zhejiang University, Hangzhou, China.

Schwannoma is a type of neurogenic tumor usually found in the posterior mediastinum. Most schwannomas range in size from 2 to 3 cm; some can exceed 10 cm. We herein report a case of a rare, large mediastinal schwannoma whose size is 20 cm × 15 cm × 12 cm, which has rarely reported before. Read More

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http://dx.doi.org/10.4103/1119-3077.188701DOI Listing
January 2018
5 Reads

[Transmanubrial Osteomuscular-sparing Approach for Resection of Superior Mediastinal Schwannoma].

Kyobu Geka 2016 Aug;69(9):760-3

Department of Cardiovascular and Thoracic Surgery, Hokkaido University, Graduate School of Medicine, Sapporo, Japan.

Various approaches can be applied to resect superior mediastinal tumor. It is important to choose the procedure according to the location, size, and characteristics of the tumor in order to perform safe procedure surgery because of distinctive anatomy of this site. We hereby report on a case of Schwannoma of the superior mediastinum resected by the transmanubrial approach. Read More

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August 2016
18 Reads

[The resection of the huge mediastinal schwannoma by the jugulal approach: one case report].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2016 Feb;30(4):329-30

Neurogenic tumors located in the posterior mediastinum, generally require surgery which be confronted with greater risk,therefore, to design the best surgical approach and surgical methods is essential. A 67-year-old female patient had pharyngeal foreign body sensation and dysphagia. Thyroid ultrasound showed the right thyroid had a little nodule, and the left thyroid had a hypoechoic lumps. Read More

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February 2016
7 Reads

Imaging of Thoracic Neurogenic Tumors.

AJR Am J Roentgenol 2016 Sep 24;207(3):552-61. Epub 2016 Jun 24.

6 Department of Radiology and Radiological Sciences, Uniformed Services University of the Health Sciences, Bethesda, MD.

Objective: Thoracic neurogenic neoplasms may be a diagnostic challenge both clinically and radiologically, ranging from benign, incidentally discovered tumors to aggressive, symptomatic malignancies. These tumors may originate from any nervous structure within the chest and are derived from cells of the nerve sheath, autonomic ganglia, or paraganglia. The nervous anatomy of the thorax is complex, and neurogenic tumors may be found in any mediastinal compartment or in the chest wall. Read More

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http://dx.doi.org/10.2214/AJR.16.16018DOI Listing
September 2016
10 Reads

Giant Benign Mediastinal Masses Extending into the Pleural Cavity.

Surg J (N Y) 2016 Apr 10;2(2):e46-e50. Epub 2016 Jun 10.

Department of Thoracic Surgery, Medical Faculty, Selçuk University, Konya, Turkey.

 The aim of the study was to evaluate the results of surgery to remove huge mediastinal masses and their pathology. Surgical resection was chosen for accurate diagnosis and treatment of the huge mediastinal masses extending into the pleural cavity.  Records were reviewed for eight patients who had the diagnosis of huge benign mediastinal masses and who underwent operation; details of the patients and operations were recorded. Read More

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http://dx.doi.org/10.1055/s-0036-1584519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5553481PMC
April 2016
3 Reads

Dumbbell Shaped Schwannoma of the Lateral Chest Wall masquandering as a soft tissue sarcoma.

Indian J Surg Oncol 2015 Sep 25;6(3):307-10. Epub 2015 Jun 25.

Cancer Institute (WIA), 38, Sardar Patel Rd, Adyar, Chennai, 600036 India.

Schwannomas are benign, slow growing nerve sheath tumours of Schwann cell origin. They predominantly are known to involve the head, neck and the flexor surfaces of the extremities, retroperitoneum and the posterior spinal roots. The chest wall is a relatively uncommon location for a schwannoma, the vast majority of which are intra-thoracic, which are usually located in the posterior mediastinum and bulge into the thoracic cavity. Read More

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http://dx.doi.org/10.1007/s13193-015-0435-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856675PMC
September 2015
52 Reads

Gynaecological Perspective of Schwannoma: A Rare Pelvic Tumour.

J Clin Diagn Res 2016 Apr 1;10(4):QD03-5. Epub 2016 Apr 1.

Professor, Department of Pathology, Saveetha Medical College and Hospital , Chennai, India .

Schwannomas are benign tumours that arise from Schwann cells of nerve fibres. They commonly occur in the head, neck, mediastinum and extremities but pelvic occurrence is rare. We report a rare case of retroperitoneal tumour with Gynaec presentation. Read More

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http://dx.doi.org/10.7860/JCDR/2016/16301.7587DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4866198PMC
April 2016
3 Reads

Symptomatic pericardial schwannoma treated with video-assisted thoracic surgery: a case report.

J Thorac Dis 2016 May;8(5):E349-52

1 Division of Thoracic Surgery, Department of Surgery, 2 Department of Pathology, 3 Division of Pulmonary and Critical Care, Department of Internal Medicine, Tri-Service General Hospital, Taipei, Taiwan.

Intrathoracic schwannomas are neurogenic tumors derived from the Schwann cells of the nerve sheath, most often seen in the posterior mediastinum with anatomical correlations to nerves. Although they are typically benign, a malignant transformation can occur, and thoracotomy instead of video-assisted thoracoscopic surgery (VATS) is required to achieve a complete resection. Only a few cases of pericardial schwannoma have been reported so far. Read More

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http://dx.doi.org/10.21037/jtd.2016.03.40DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842797PMC
May 2016
5 Reads

[Schwannoma in the Middle Mediastinum Originating from the Vagal Nerve;Report of a Case].

Kyobu Geka 2016 Mar;69(3):236-9

Department of Thoracic Surgery, Higashiosaka Municipal Hospital, Higashiosaka, Japan.

A 44-year-old woman was referred to our department with a mediastinal tumor detected by computed tomography performed as a preoperative examination for cervical cancer. There was a 32 mm solid mass in the area surrounded by the descending thoracic aorta, esophagus, left atrium, left lower lobe, and mediastinal pleura. The tumor was removed thoracoscopically. Read More

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March 2016
4 Reads

A case of schwannoma of the mesoesophagus displaced from the left to the right of the posterior mediastinum.

Gen Thorac Cardiovasc Surg 2017 Jan 19;65(1):59-62. Epub 2016 Mar 19.

Department of Thoracic Surgery, Osaka Medical College Hospital, 2-7 Daigaku-cho, Takatsuki, 569-8686, Japan.

Although schwannomas are the most common neurogenic tumors found in the thorax, schwannomas of the mesoesophagus are extremely rare. We report a case of an 80-year-old man having a tumor in contact with the esophagus in the left posterior mediastinum. A preoperative follow-up computed tomography scan showed tumor displacement from the left to the right of the posterior mediastinum. Read More

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http://dx.doi.org/10.1007/s11748-016-0641-4DOI Listing
January 2017
6 Reads

Malignant Schwannoma of the Esophagus: A Rare Case Report.

Korean J Thorac Cardiovasc Surg 2016 Feb 5;49(1):63-6. Epub 2016 Feb 5.

Department of Radiodiagnosis, All India Institute of Medical Sciences.

Neurogenic tumors are the most prevalent tumors of the mediastinum, and schwannomas are the most common type of neurogenic tumor. Primary neurogenic neoplasm of the esophagus is uncommon and malignant schwannoma of the esophagus is extremely rare. We report a case of a 27-year-old female presenting with dysphagia and palpitations who was found to have a lobulated tumor in the mediastinum that was compressing the esophageal lumen. Read More

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http://dx.doi.org/10.5090/kjtcs.2016.49.1.63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757402PMC
February 2016
1 Read

Intrathoracic Malignant Peripheral Nerve Sheath Tumor: Histopathological and Immunohistochemical Features.

Iran J Pathol 2015 ;10(1):74-8

Department of Pathology, Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India.

Malignant peripheral nerve sheath tumor (MPNST) is a rare nerve sheath tumor derived from Schwann cells or pleuripotent cells of neural crest. Neurogenic tumors make about 10-20% of all mediastinal tumors. Incidence of MPNST is 0. Read More

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http://jco.ascopubs.org/content/26/13/2216.full.pdf
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539789PMC
October 2015
5 Reads

[Mediastinal Hemangioma with Literature Review;Report of a Case].

Kyobu Geka 2015 Jul;68(7):556-9

Department of Surgery and Oncology, Kyushu University, Fukuoka, Japan.

A 58-year-old woman visited a local physician for evaluation of collagen disease and screening computed tomography (CT) showed a posterior mediastinal tumor. After referral to our hospital, CT and magnetic resonance imaging (MRI) showed a mass, approximately 2 cm in diameter, located on the right of the 1st thoracic vertebra. Since a neurogenic tumor was suspected, thoracoscopic excision was performed. Read More

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July 2015
4 Reads

An Unusual Presentation of a Posterior Mediastinal Schwannoma Associated with Traumatic Hemothorax.

Case Rep Surg 2015 7;2015:175645. Epub 2015 May 7.

Department of Surgery, Division of Trauma and Surgical Critical Care, The Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.

Schwannomas of the thoracic cavity are typically an asymptomatic, benign neurogenic neoplasm of the posterior mediastinum. In this case, we present a traumatic hemothorax as the initial presentation for a previously undiscovered mediastinal mass. The patient presented with shortness of breath and right-sided chest pain after being struck in the chest with a soccer ball. Read More

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http://dx.doi.org/10.1155/2015/175645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439471PMC
June 2015
2 Reads

A Case of Mediastinal Granular Cell Tumor with Horner's Syndrome.

Ann Thorac Cardiovasc Surg 2015 2;21(6):567-9. Epub 2015 Jun 2.

Center of Chest Medicine and Surgery, Ehime University, Toon, Ehime, Japan.

Granular cell tumor (GCT) is found in various organs but is rare in the mediastinum. We report a case of mediastinal GCT in a 19-year-old woman who presented with left ptosis and miosis. CT and MRI revealed a 29-mm well-circumscribed tumor located close to the first thoracic vertebra with features suggesting a neurogenic tumor. Read More

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http://dx.doi.org/10.5761/atcs.cr.15-00112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4905036PMC
October 2016
3 Reads

Abducens nerve palsy after schwannoma resection.

Ann Thorac Surg 2015 Feb;99(2):694-5

Unité de Chirurgie Thoracique, Hôpital Cochin, AP-HP, Paris, France.

Tumors of the posterior mediastinum are mostly neurogenic and could involve the intervertebral foramen and the medullary canal. We describe the case of a patient who underwent surgery for a nerve sheet tumor originating at the level of the right second neural root. Resection was associated with an incidental dural tear and cerebrospinal fluid leak that was promptly repaired. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2014.04.070DOI Listing
February 2015
7 Reads

Treatment of large thoracic and lumbar paraspinal schwannoma.

Acta Neurochir (Wien) 2015 Mar 11;157(3):531-8. Epub 2015 Jan 11.

Department of Neurosurgery, University Medical Center Hamburg-Eppendorf, Martinistr. 52, 20246, Hamburg, Germany.

Background: Paraspinal neurogenic tumors usually expand into the mediastinum and retroperitoneum and can reach a considerable size before they become symptomatic. Such large tumors are rare. We describe 14 cases of large schwannomas (>2. Read More

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http://dx.doi.org/10.1007/s00701-014-2320-5DOI Listing
March 2015
36 Reads

Liposarcomas of the posterior mediastinum: clinicopathologic study of 18 cases.

Mod Pathol 2015 May 5;28(5):721-31. Epub 2014 Dec 5.

Department of Pathology and Laboratory Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.

Sarcomas of the posterior mediastinum are rare and correspond mostly to neurogenic tumors. We studied 18 cases of liposarcoma presenting in the posterior mediastinum; because of their unusual location, some of these tumors posed difficulties for diagnosis. There were 11 men and 7 women aged 29-87 years (mean: 57). Read More

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http://dx.doi.org/10.1038/modpathol.2014.152DOI Listing
May 2015
12 Reads

Massive hemoptysis: a rare presentation of posterior mediastinal, giant, benign vagal schwannoma.

Arch Iran Med 2014 Nov;17(11):779-82

Department of Cardiovascular and Thoracic Surgery, Medical College, Kolkata, West Bengal, India.

Schwannomas are rare neurogenic tumor originating from Schwann cells of the nerve sheath, most frequently encountered type of posterior mediastinal tumors. In most cases, schwannomas are benign, malignant and multiple schwannomas are rare. Histopathologically, the tumor is composed of fascicles of spindle cells, which are strongly positive for S-100 proteins. Read More

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http://dx.doi.org/0141711/AIM.0013DOI Listing
November 2014
3 Reads
1.110 Impact Factor

Giant intrathoracic left-sided vagal schwannoma.

Thorac Cardiovasc Surg Rep 2013 Dec 26;2(1):19-22. Epub 2013 Mar 26.

Department of Surgery, Marburg University Hospital, Marburg, Germany.

Extensive intrathoracic tumors are rarely diagnosed radiologically without pre-existing symptoms. If located in the posterior mediastinum, it is most probably a neurogenic tumor. Schwannoma is the most frequent neurogenic neoplasia in this location, and most schwannomas are benign. Read More

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http://dx.doi.org/10.1055/s-0033-1337368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4176068PMC
December 2013
7 Reads

Videothoracoscopy in the treatment of benign neurogenic tumours of the posterior mediastinum.

Wideochir Inne Tech Maloinwazyjne 2014 Sep 23;9(3):315-8. Epub 2014 Jul 23.

Department of Thoracic Surgery, Medical University of Lodz, Lodz, Poland.

Introduction: The indications for videothoracoscopy are very broad and include the treatment of mediastinal tumours.

Aim: To present our experience of using the minimally invasive technique in treating benign neurogenic tumours.

Material And Methods: Twenty-two patients were treated due to tumours of the posterior mediastinum from 2003 to 2012. Read More

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http://dx.doi.org/10.5114/wiitm.2014.44255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198653PMC
September 2014
6 Reads

Mediastinal neurothekeoma: a rare tumor.

Asian Cardiovasc Thorac Ann 2015 Jun 6;23(5):593-5. Epub 2014 Oct 6.

Department of Thoracic Surgery, Gazi University School of Medicine, Ankara, Turkey.

Neurothekeoma, also known as nerve sheath myxoma, is a benign nerve sheath tumor that usually arises in the cutaneous nerves of the head, neck, or upper extremities. Extracutaneous placement is very rare. Mediastinal neurothekeoma has not previously been reported in the English literature. Read More

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http://dx.doi.org/10.1177/0218492314552857DOI Listing
June 2015
4 Reads

Neck and superior mediastinal granular cell tumor excised via a combined approach.

Auris Nasus Larynx 2015 Feb 26;42(1):72-6. Epub 2014 Sep 26.

Department of Otolaryngology, Kyoto-Katsura Hospital, Yamada Hirao cho 17, Nishikyou-ku, Kyoto, 615 8256 Japan. Electronic address:

Granular cell tumor (GCT) is an uncommon tumor of Schwann cell origin. GCT occurs in various sites throughout the body, but mediastinal GCT is very rare. We present an extremely rare case of GCT of the neck and superior mediastinum. Read More

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http://dx.doi.org/10.1016/j.anl.2014.09.001DOI Listing
February 2015
1 Read

Thoracoscopic resection of a vagal schwannoma in the superior mediastinum: A case report.

Oncol Lett 2014 Jul 7;8(1):461-463. Epub 2014 May 7.

Department of Thoracic Surgery, Lanzhou General Hospital, Lanzhou Command, Lanzhou, Gansu 730050, P.R. China.

Neurogenic tumors are the most common type of mediastinal tumor and constitute the majority of neoplasms of the posterior mediastinum. Schwannomas originating from the intrathoracic vagus nerve are extremely rare. The present study describes the case of a 58-year-old man with a large vagal schwannoma in the left superior mediastinum. Read More

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http://dx.doi.org/10.3892/ol.2014.2116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063578PMC
July 2014
6 Reads

[Mediastinal schwannoma resected through the 10th intercostal space via a posterolateral thoracotomy].

Kyobu Geka 2014 Jun;67(6):459-62

Department of Thoracic Surgery, Chigasaki Municipal Hospital, Chigasaki, Japan.

A 64-year-old woman with a mediastinal tumor incidentally found on computed tomography( CT) was referred to our hospital. CT and magnetic resonance imaging( MRI) showed the tumor had a clear border and was located on the right side of the 12th thoracic vertebra, spanning the thoracic and abdominal cavities. She was suspected of having a benign neurogenic tumor of the mediastinum. Read More

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June 2014
5 Reads

Giant thoracoabdominal ganglioneuroblastoma in a 17-year-old patient.

Asian Cardiovasc Thorac Ann 2014 Jul 16;22(6):739-41. Epub 2013 Aug 16.

Department of Cardiothoracic Surgery, Wessex Cardiac Centre, Southampton University Hospitals NHS Trust, Southampton, UK.

The most common malignant neurogenic tumors in children are neuroblastic tumors, classified as ganglioneuroblastoma or neuroblastoma. Ganglioneuroblastomas usually occur at the sympathetic ganglia in the mediastinum, whereas neuroblastomas occur in the abdominal cavity. We describe a case of large posterior mediastinal ganglioneuroblastoma extending from the aortic arch to the left renal hilum in a 17-year-old boy. Read More

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http://dx.doi.org/10.1177/0218492313490410DOI Listing
July 2014
2 Reads

Vocal cord paralysis and its etiologies: a prospective study.

J Cardiovasc Thorac Res 2014 4;6(1):47-50. Epub 2014 Mar 4.

Department of ENT, Tabriz University of Medical Sciences, Tabriz, Iran.

Introduction: Vocal cord paralysis is a common symptom of numerous diseases and it may be due to neurogenic or mechanical fixation of the cords. Paralysis of the vocal cords is just a symptom of underlying disease in some cases; so, clinical diagnosis of the underlying cause leading to paralysis of the vocal cords is important. This study evaluates the causes of vocal cord paralysis. Read More

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http://dx.doi.org/10.5681/jcvtr.2014.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3992732PMC
April 2014
2 Reads

Case report: Large adrenal ganglioneuroma.

Int J Surg Case Rep 2014 13;5(5):253-5. Epub 2014 Mar 13.

Department of Urology, Duzce University School of Medicine, Duzce, Turkey.

Introduction: Ganglioneuromas are localized tumors derived from neural crest tissues. Characteristically, they originate in the posterior mediastinum. Pure adrenal gangliomas are extremely rare. Read More

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http://dx.doi.org/10.1016/j.ijscr.2014.03.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008857PMC
April 2014
4 Reads

Morphological differences between schwannomas and ganglioneuromas in the mediastinum: utility of the craniocaudal length to major axis ratio.

Br J Radiol 2014 Apr;87(1036):20130777

Objective: To evaluate the diagnostic value of the craniocaudal length (CC) to major axis ratio (CC/M R) for differentiating between schwannoma and ganglioneuroma in the mediastinum on CT/MRI.

Methods: 22 schwannomas (Group A: 7 schwannomas in the posterior mediastinum; Group B, 15 schwannomas located in the chest wall or regions of the mediastinum other than the posterior mediastinum) and 14 ganglioneuromas in the posterior mediastinum (Group C) were evaluated. For each tumour, the major and minor axes on the largest transaxial image and the CC were measured on CT/MRI. Read More

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http://dx.doi.org/10.1259/bjr.20130777DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067012PMC
April 2014
2 Reads

Surgery of benign neurogenic tumors in adults: single institution experience.

Pan Afr Med J 2014 17;19:288. Epub 2014 Nov 17.

Department of Thoracic Surgery, Mohamed V Military Academic Hospital, Rabat, Morocco.

The objective of this work is to review retrospectively our experience with 17 patients presenting with benign neurogenic tumors, managed in the department of thoracic surgery, Mohamed V Military Academic Hospital, Rabat, Morocco. Between 2003 and 2011, seventeen patients were surgically treated for benign neurogenic tumors of the mediastinum, among 112 mediastinal tumors operated during the same period. The mean age of the 17 patients was 46 years, including 11 females and 6 males. Read More

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http://dx.doi.org/10.11604/pamj.2014.19.288.4929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391890PMC
November 2015
4 Reads