16,855 results match your criteria NeuroImage[Journal]


Neural correlates of cognitive dysfunction in fibromyalgia patients: Reduced brain electrical activity during the execution of a cognitive control task.

Neuroimage Clin 2019 Apr 8;23:101817. Epub 2019 Apr 8.

Departamento de Psicoloxía Clínica e Psicobioloxía, Facultade de Psicoloxía, Universidade de Santiago de Compostela, Santiago de Compostela, Spain.

Objectives: Fibromyalgia (FM) is a generalized chronic pain syndrome of unknown aetiology. Although FM patients frequently complain of cognitive dysfunction, this is one of the least studied symptoms. Research on brain activity associated with the perceived cognitive impairment is particularly scarce. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101817DOI Listing

Determinants of structural segregation and patterning in the human cortex.

Neuroimage 2019 Apr 14. Epub 2019 Apr 14.

Department of Anatomy & Neurobiology, University of California, Irvine, USA.

This study aimed at uncovering mechanisms that govern the spatio-temporal patterning of the human cortex and its structural variability, and drawing links between fetal brain development and variability in adult brains. A data-driven analytic approach based on structural MR images revealed the following findings: (1) The cortical surface can be subdivided into 13 independent regions ("communities") based on macroscopic features. (2) Thirty centers of low inter-subject variability were found in major sulci on the cortical surface. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10538119193031
Publisher Site
http://dx.doi.org/10.1016/j.neuroimage.2019.04.031DOI Listing
April 2019
1 Read

How pattern information analyses of semantic brain activity elicited in language comprehension could contribute to the early identification of Alzheimer's Disease.

Neuroimage Clin 2019 Mar 26;22:101788. Epub 2019 Mar 26.

Department of Neuroscience, University of Rochester Medical Center, United States of America; School of Nursing, University of Rochester Medical Center, United States of America; Department of Psychiatry, University of Rochester Medical Center, United States of America; Department of Neurology, University of Rochester Medical Center, United States of America; Department of Brain and Cognitive Sciences, University of Rochester, United States of America. Electronic address:

Alzheimer's disease (AD) is associated with a loss of semantic knowledge reflecting brain pathophysiology that begins years before dementia. Identifying early signs of pathophysiology induced dysfunction in the neural systems that access and process words' meaning could therefore help forecast dementia. This article reviews pioneering studies demonstrating that abnormal functional Magnetic Resonance Imaging (fMRI) response patterns elicited in semantic tasks reflect both AD-pathophysiology and the hereditary risk of AD, and also can help forecast cognitive decline. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101788DOI Listing

Disturbed neurovascular coupling in type 2 diabetes mellitus patients: Evidence from a comprehensive fMRI analysis.

Neuroimage Clin 2019 Mar 27;22:101802. Epub 2019 Mar 27.

Department of Radiology & Functional and Molecular Imaging Key Lab of Shaanxi Province, Tangdu Hospital, Fourth Military Medical University, 569 Xinsi Road, Xi'an 710038, Shaanxi, China. Electronic address:

Background: Previous studies presumed that the disturbed neurovascular coupling to be a critical risk factor of cognitive impairments in type 2 diabetes mellitus (T2DM), but distinct clinical manifestations were lacked. Consequently, we decided to investigate the neurovascular coupling in T2DM patients by exploring the MRI relationship between neuronal activity and the corresponding cerebral blood perfusion.

Methods: Degree centrality (DC) map and amplitude of low-frequency fluctuation (ALFF) map were used to represent neuronal activity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101802DOI Listing

Impaired hippocampal development and outcomes in very preterm infants with perinatal brain injury.

Neuroimage Clin 2019 Mar 18;22:101787. Epub 2019 Mar 18.

Department of Pediatrics, Washington University in St. Louis, St. Louis, United States; Department of Neurology, Washington University in St. Louis, St. Louis, United States; Mallinckrodt Institute of Radiology, Washington University in St. Louis, St. Louis, United States.

Preterm infants are at high risk for brain injury during the perinatal period. Intraventricular hemorrhage and periventricular leukomalacia, the two most common patterns of brain injury in prematurely-born children, are associated with poor neurodevelopmental outcomes. The hippocampus is known to be critical for learning and memory; however, it remains unknown how these forms of brain injury affect hippocampal growth and how the resulting alterations in hippocampal development relate to childhood outcomes. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101787DOI Listing

Default mode network connectivity is associated with long-term clinical outcome in patients with schizophrenia.

Neuroimage Clin 2019 Apr 1;22:101805. Epub 2019 Apr 1.

Department of Mental Health Research, National Center for Mental Health, Seoul, Republic of Korea. Electronic address:

This study investigated whether resting-state functional connectivity is associated with long-term clinical outcomes of patients with schizophrenia. Resting-state brain images were obtained from 79 outpatients with schizophrenia and 30 healthy controls (HC), using a 3 T-MRI scanner. All patients were 20-50 years old with >3 years' duration of illness and appeared clinically stable. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101805DOI Listing

Dynamic functional connectivity changes in dementia with Lewy bodies and Alzheimer's disease.

Neuroimage Clin 2019 Apr 3;22:101812. Epub 2019 Apr 3.

Institute of Neuroscience, Newcastle University, Campus for Ageing and Vitality, Newcastle upon Tyne NE4 5PL, United Kingdom.

We studied the dynamic functional connectivity profile of dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) compared to controls, how it differs between the two dementia subtypes, and a possible relation between dynamic connectivity alterations and temporally transient clinical symptoms in DLB. Resting state fMRI data from 31 DLB, 29 AD, and 31 healthy control participants were analyzed using dual regression to determine between-network functional connectivity. Subsequently, we used a sliding window approach followed by k-means clustering and dynamic network analyses to study dynamic functional connectivity. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101812DOI Listing

Selection of neuropsychological tasks from a language test battery that optimally related to the function of each cortical area: Toward making a cognitive cortical map.

Authors:
Yasuhiro Suzuki

Neuroimage Clin 2019 Mar 28;22:101799. Epub 2019 Mar 28.

Department of Neurology, Shizuoka Saiseikai general hospital, 1-1-1 Oshika, Suruga-ku, Shizuoka 422-8527, Japan. Electronic address:

We developed a cortical language map from performance data on a language test battery in patients with brain lesions. The research problem was how to select the subtest that was most related to the function of each cortical area from the battery. When studied by voxel-based lesion-symptom mapping (VLSM), patients were divided into two groups: those with and without a lesion at each particular region. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101799DOI Listing

Effect of age, ethnicity, sex, cognitive status and APOE genotype on amyloid load and the threshold for amyloid positivity.

Neuroimage Clin 2019 Mar 27;22:101800. Epub 2019 Mar 27.

Florida ADRC, USA; University of Florida College of Medicine, Gainesville, FL, USA.

The threshold for amyloid positivity by visual assessment on PET has been validated by comparison to amyloid load measured histopathologically and biochemically at post mortem. As such, it is now feasible to use qualitative visual assessment of amyloid positivity as an in-vivo gold standard to determine those factors which can modify the quantitative threshold for amyloid positivity. We calculated quantitative amyloid load, measured as Standardized Uptake Value Ratios (SUVRs) using [18-F]florbetaben PET scans, for 159 Hispanic and non-Hispanic participants, who had been classified clinically as Cognitively Normal (CN), Mild Cognitive Impairment (MCI) or Dementia (DEM). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101800DOI Listing

The effect of ApoE ε4 on longitudinal brain region-specific glucose metabolism in patients with mild cognitive impairment: a FDG-PET study.

Neuroimage Clin 2019 Mar 28;22:101795. Epub 2019 Mar 28.

The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, United States; Department of Nuclear Medicine, Peking University First Hospital, Beijing, China; Mallinckrodt Institute of Radiology, Washington University in St. Louis School of Medicine, St. Louis, MO 63110, United States. Electronic address:

While the ApoE ε4 allele is a known risk factor for mild cognitive impairment (MCI) and Alzheimer's disease, brain region specific effects remain elusive. In this study, we investigate whether the ApoE ε4 allele exhibits brain region specific effects in longitudinal glucose uptake among patients with MCI from the Alzheimer's Disease Neuroimaging Initiative (ADNI). Preprocessed FDG PET images, MRIs, and demographic information were downloaded from the ADNI database. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101795DOI Listing

Adolescent binge drinking disrupts normal trajectories of brain functional organization and personality maturation.

Neuroimage Clin 2019 Mar 31;22:101804. Epub 2019 Mar 31.

School of Mathematical Sciences, Fudan University, Shanghai 200433, PR China; Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai 200433, PR China; Department of Computer Science, University of Warwick, Coventry, UK; Collaborative Innovation Center for Brain Science, Fudan University, Shanghai, PR China; Shanghai Center for Mathematical Sciences, Shanghai, PR China; Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence (Fudan University), Ministry of Education, PR China.

Adolescent binge drinking has been associated with higher risks for the development of many health problems throughout the lifespan. Adolescents undergo multiple changes that involve the co-development processes of brain, personality and behavior; therefore, certain behavior, such as alcohol consumption, can have disruptive effects on both brain development and personality maturation. However, these effects remain unclear due to the scarcity of longitudinal studies. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101804DOI Listing

Attention network dysfunction underlies memory impairment in posterior cortical atrophy.

Neuroimage Clin 2019 Mar 13;22:101773. Epub 2019 Mar 13.

Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK; Research Institute for the Care of the Elderly, Royal United Hospital, Bath, UK. Electronic address:

Accumulating evidence suggests that memory is impaired in posterior cortical atrophy (PCA), alongside the early and defining visual disorder. The posterior parietal cortex is a key region of pathology in PCA and memory impairment may be the result of dysfunction of parietally dependent network function rather than the medial temporal lobe dependent dysfunction that defines the storage deficits in typical Alzheimer's disease. We assessed episodic memory performance and network function in16 PCA patients and 19 healthy controls who underwent structural and resting-state functional MRI and neuropsychological testing. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101773DOI Listing

Network based statistics reveals trophic and neuroprotective effect of early high dose erythropoetin on brain connectivity in very preterm infants.

Neuroimage Clin 2019 Apr 1;22:101806. Epub 2019 Apr 1.

Department of Neonatology, University Hospital Zurich, Zurich, Switzerland; Department of Neonatology and Pediatric Intensive Care, University Children's Hospital Zurich, Zurich, Switzerland.

Periventricular white matter injury is common in very preterm infants and it is associated with long term neurodevelopmental impairments. While evidence supports the protective effects of erythropoetin (EPO) in preventing injury, we currently lack the complete understanding of how EPO affects the emergence and maturation of anatomical brain connectivity and function. In this case-control study, connectomic analysis based on diffusion MRI tractography was applied to evaluate the effect of early high-dose EPO in preterm infants. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101806DOI Listing

Altered frontal white matter asymmetry and its implications for cognition in schizophrenia: A tractography study.

Neuroimage Clin 2019 Mar 15;22:101781. Epub 2019 Mar 15.

Department of Methods and Experimental Psychology, Faculty of Psychology and Education, University of Deusto, Avenida de las Universidades, 24, 48007 Bilbao, Biscay, Spain.

Background: White matter (WM) alterations are well documented in schizophrenia. Abnormalities in interhemispheric fibers appear to account for altered WM asymmetry in the illness. However, the regional specificity (e. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101781DOI Listing

The neural basis of external responsiveness in prolonged disorders of consciousness.

Neuroimage Clin 2019 Mar 26;22:101791. Epub 2019 Mar 26.

School of Psychology, The University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom; Centre for Human Brain Health, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom. Electronic address:

Objective: To investigate the structural integrity of fibre tracts underlying overt motor behaviour in PDOC.

Methods: This cross-sectional study examined 15 PDOC patients and 22 healthy participants. Eight PDOC patients met the criteria for the vegetative state, 5 met the criteria for the minimally conscious state and 2 met the criteria for emerging from the minimally conscious state. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S22131582193014
Publisher Site
http://dx.doi.org/10.1016/j.nicl.2019.101791DOI Listing
March 2019
1 Read

Fixel-based analysis of the preterm brain: Disentangling bundle-specific white matter microstructural and macrostructural changes in relation to clinical risk factors.

Neuroimage Clin 2019 Apr 10;23:101820. Epub 2019 Apr 10.

Centre for the Developing Brain, School of Biomedical Engineering & Imaging Sciences, King''s College London, UK. Electronic address:

Diffusion MRI (dMRI) studies using the tensor model have identified abnormal white matter development associated with perinatal risk factors in preterm infants studied at term equivalent age (TEA). However, this model is an oversimplification of the underlying neuroanatomy. Fixel-based analysis (FBA) is a novel quantitative framework, which identifies microstructural and macrostructural changes in individual fibre populations within voxels containing crossing fibres. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101820DOI Listing

Efficacy of weight loss intervention can be predicted based on early alterations of fMRI food cue reactivity in the striatum.

Neuroimage Clin 2019 Mar 27;23:101803. Epub 2019 Mar 27.

Brain Imaging Centre, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Budapest H-1117, Hungary. Electronic address:

Increased fMRI food cue reactivity in obesity, i.e. higher responses to high- vs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101803DOI Listing

Multivariate prediction of functional outcome using lesion topography characterized by acute diffusion tensor imaging.

Neuroimage Clin 2019 Apr 10;23:101821. Epub 2019 Apr 10.

Institut du Cerveau et de la Moelle épinière, ICM, Inserm U 1127, CNRS UMR 7225, Sorbonne Université, F-75013 Paris, France; ICM Team Movement Investigation and Therapeutics, France; AP-HP, Urgences Cérébro-Vasculaires, Hôpital Pitié-Salpêtrière, Paris, France. Electronic address:

The relationship between stroke topography and functional outcome has largely been studied with binary manual lesion segmentations. However, stroke topography may be better characterized by continuous variables capable of reflecting the severity of ischemia, which may be more pertinent for long-term outcome. Diffusion Tensor Imaging (DTI) constitutes a powerful means of quantifying the degree of acute ischemia and its potential relation to functional outcome. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101821DOI Listing

APOE-ε4 risk variant for Alzheimer's disease modifies the association between cognitive performance and cerebral morphology in healthy middle-aged individuals.

Neuroimage Clin 2019 Apr 8;23:101818. Epub 2019 Apr 8.

Barcelonaβeta Brain Research Center, Pasqual Maragall Foundation, Barcelona, Spain; Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Madrid, Spain; Universitat Pompeu Fabra, Barcelona, Spain. Electronic address:

The APOE-ε4 genotype is the highest genetic risk factor for Alzheimer's disease (AD). In cognitively unimpaired individuals, it has been related to altered brain morphology, function and earlier amyloid beta accumulation. However, its impact on cognitive performance is less evident. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101818DOI Listing

Diurnal changes in human brain glutamate + glutamine levels in the course of development and their relationship to sleep.

Neuroimage 2019 Apr 13. Epub 2019 Apr 13.

Children's Research Center, University Children's Hospital Zurich, Steinwiesstrasse 75, 8032, Zurich, Switzerland; Child Development Center, University Children's Hospital Zurich, Steinwiesstrasse 75, 8032, Zurich, Switzerland; Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric Hospital University of Zurich, Lenggstrasse 31, 8032, Zurich, Switzerland. Electronic address:

Sleep slow waves during non-rapid eye movement (NREM) sleep play a crucial role in maintaining cortical plasticity, a process that is especially important in the developing brain. Children show a considerably larger overnight decrease in slow wave activity (SWA; the power in the EEG frequency band between 1 and 4.5 Hz during NREM sleep), which constitutes the primary electrophysiological marker for the restorative function of sleep. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2019.04.040DOI Listing

Low-frequency cortical responses to natural speech reflect probabilistic phonotactics.

Neuroimage 2019 Apr 13. Epub 2019 Apr 13.

Laboratoire des Systèmes Perceptifs, UMR 8248, CNRS, France; Département d'Etudes Cognitives, Ecole Normale Supérieure, PSL University, France; UCL Ear Institute, London, United Kingdom.

Humans comprehend speech despite the various challenges such as mispronunciation and noisy environments. Our auditory system is robust to these thanks to the integration of the sensory input with prior knowledge and expectations built on language-specific regularities. One such regularity regards the permissible phoneme sequences, which determine the likelihood that a word belongs to a given language (phonotactic probability; "blick" is more likely to be an English word than "bnick"). Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2019.04.037DOI Listing

Stimulus-response recoding during inhibitory control is associated with superior frontal and parahippocampal processes.

Neuroimage 2019 Apr 13. Epub 2019 Apr 13.

Cognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine of the TU Dresden, Germany. Electronic address:

Inhibitory control is affected by perceptual processes, but the mechanisms how perceptual features affect response inhibition are poorly understood. Theoretical frameworks detailing how variations in stimulus features that create overlaps between response categories can affect action control, like the Theory of Event Coding (TEC), have not been transferred to inhibitory control. We present a novel Go/Nogo paradigm in which we varied stimulus feature overlap between Go and Nogo trials. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2019.04.035DOI Listing

Connectivity derived thalamic segmentation: Separating myth from reality.

Neuroimage Clin 2019 Mar 20:101758. Epub 2019 Mar 20.

Unit of Functional Neurosurgery, Department of Clinical and Movement Neurosciences, UCL Institute of Neurology, Queen Square, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101758DOI Listing

Complexities of connectivity-based DBS targeting: Rebirth of the debate on thalamic and subthalamic treatment of tremor.

Neuroimage Clin 2019 Mar 20:101761. Epub 2019 Mar 20.

Center of Neurology and Neurosurgery Associates (NeuroCENNA), BP-A Beneficência Portuguesa de São Paulo, São Paulo, Brazil.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101761DOI Listing

Functional reorganization of neural networks involved in emotion regulation following trauma therapy for complex trauma disorders.

Neuroimage Clin 2019 Apr 2;23:101807. Epub 2019 Apr 2.

Clienia Littenheid AG, Hospital for Psychiatry and Psychotherapy, Littenheid, Switzerland; Department of Psychiatry, Psychotherapy, and Psychosomatics, University Hospitals and University of Halle (Saale), Halle, Germany.

Objectives: We investigated whether patients with complex interpersonal trauma engage neural networks that are commonly activated during cognitive reappraisal and responding naturally to affect-laden images. In this naturalistic study, we examined whether trauma treatment not only reduces symptoms but also changes neural networks involved in emotional control.

Methods: Before and after eight weeks of phase-oriented inpatient trauma treatment, patients (n = 28) with complex posttraumatic stress disorder (cPTSD) and complex dissociative disorders (CDD) performed a cognitive reappraisal task while electroencephalography (EEG) was registered. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S22131582193015
Publisher Site
http://dx.doi.org/10.1016/j.nicl.2019.101807DOI Listing
April 2019
2 Reads

Cortical and subcortical T1 white/gray contrast, chronological age, and cognitive performance.

Neuroimage 2019 Apr 12. Epub 2019 Apr 12.

AI Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.

The maturational schedule of typical brain development is tightly constrained; deviations from it are associated with cognitive atypicalities, and are potentially predictive of developmental disorders. Previously, we have shown that the white/gray contrast at the inner border of the cortex is a good predictor of chronological age, and is sensitive to aspects of brain development that reflect cognitive performance. Here we extend that work to include the white/gray contrast at the border of subcortical structures. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10538119193030
Publisher Site
http://dx.doi.org/10.1016/j.neuroimage.2019.04.022DOI Listing
April 2019
1 Read

Brain synchronizability, a false friend.

Authors:
D Papo J M Buldú

Neuroimage 2019 Apr 12. Epub 2019 Apr 12.

Laboratory of Biological Networks, Center for Biomedical Technology (UPM), 28223, Pozuelo de Alarcón, Madrid, Spain; Complex Systems Group & G.I.S.C., Universidad Rey Juan Carlos, 28933, Móstoles, Madrid, Spain.

Synchronization plays a fundamental role in healthy cognitive and motor function. Two issues are still poorly understood. First, how synchronization depends on the interplay between local dynamics, coupling and topology? Second, how prone to synchronization a network is, given its topological organization? To investigate the synchronizability of both anatomical and functional brain networks various studies resorted to the Master Stability Function (MSF) formalism, an elegant tool which allows analysing the stability of synchronous states in a dynamical system consisting of many coupled oscillators. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2019.04.029DOI Listing

Brain network disintegration as a final common pathway for delirium: a systematic review and qualitative meta-analysis.

Neuroimage Clin 2019 Apr 3;23:101809. Epub 2019 Apr 3.

Department of Intensive Care Medicine and Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht University, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands.

Delirium is an acute neuropsychiatric syndrome characterized by altered levels of attention and awareness with cognitive deficits. It is most prevalent in elderly hospitalized patients and related to poor outcomes. Predisposing risk factors, such as older age, determine the baseline vulnerability for delirium, while precipitating factors, such as use of sedatives, trigger the syndrome. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101809DOI Listing

Structural mapping with fiber tractography of the human cuneate fasciculus at microscopic resolution in cervical region.

Neuroimage 2019 Apr 11. Epub 2019 Apr 11.

Department of Neurosurgery, Duke University Medical Center, Durham, NC, USA.

Human spinal white matter tract anatomy has been mapped using post mortem histological information with the help of molecular tracing studies in animal models. This study used 7 Tesla diffusion MR tractography on a human cadaver that was harvested 24 hours post mortem to evaluate cuneate fasciculus anatomy in cervical spinal cord. Based on this method, for the first time much more nuanced tractographic anatomy was used to investigate possible new routes for cuneate fasciculus in the posterior and lateral funiculus. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2019.04.030DOI Listing

Functional resting-state brain connectivity is accompanied by dynamic correlations of application-dependent [F]FDG PET-tracer fluctuations.

Neuroimage 2019 Apr 11. Epub 2019 Apr 11.

Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, Eberhard Karls University Tuebingen, Germany.

Brain function is characterized by a convolution of various biochemical and physiological processes, raising the interest whether resting-state functional connectivity derived from hemodynamic scales shows underlying metabolic synchronies. Increasing evidence suggests that metabolic connectivity based on glucose consumption associated PET recordings may serve as a marker of cognitive functions and neuropathologies. However, to what extent fMRI-derived resting-state brain connectivity can also be characterized based on dynamic fluctuations of glucose metabolism and how metabolic connectivity is influenced by [F]FDG pharmacokinetics remains unsolved. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2019.04.034DOI Listing

Normative event-related potentials from sensory and cognitive tasks reveal occipital and frontal activities prior and following visual events.

Neuroimage 2019 Apr 11. Epub 2019 Apr 11.

Dept. of Movement, Human and Health Sciences, University of Rome "Foro Italico", Rome, Italy.

In the present study, we report the results from a large sample of participants (N = 136), selected based on their EEG quality, to obtain event-related potential (ERP) normative data. All participants were tested in Simple Response Task (SRT) and Discriminative Response Task (DRT). A subset of 36 participants were tested also in Passive Vision task. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2019.04.033DOI Listing

The relationship between heart rate and functional connectivity of brain regions involved in autonomic control.

Neuroimage 2019 Apr 11. Epub 2019 Apr 11.

Psychiatric Brain and Body Research Group, Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany. Electronic address:

The peripheral autonomic nervous system (ANS) adjusts the heart rate (HR) to intrinsic and extrinsic demands. It is controlled by a group of functionally connected brain regions assembling the so-called central autonomic network (CAN). More specifically, forebrain cortical regions, limbic and brainstem structures within the CAN have been identified as important components of circuits involved in HR regulation. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2019.04.014DOI Listing

Causal evidence of right temporal parietal junction involvement in implicit Theory of Mind processing.

Neuroimage 2019 Apr 11. Epub 2019 Apr 11.

School of Psychology, The University of Queensland, St Lucia, 4072, Australia.

The ability to represent the internal thoughts, beliefs and desires of others, and recognise that these might be distinct from one's own, is crucial for adaptive social interaction. Such operations are thought to tap Theory of Mind (ToM), with its importance underscored by the link between ToM impairment and a range of neurodevelopmental disorders (e.g. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10538119193031
Publisher Site
http://dx.doi.org/10.1016/j.neuroimage.2019.04.032DOI Listing
April 2019
1 Read

Time matters: Feature-specific prioritization follows feature integration in visual object processing.

Neuroimage 2019 Apr 11;196:81-93. Epub 2019 Apr 11.

Department of Psychology, Leipzig University, Neumarkt 9-19, 04109, Leipzig, Germany. Electronic address:

Objects represent a fundamental selection unit of visual attention. However, at odds with the integrated competition account, our recent study demonstrated that attentional facilitation of constituent features does not spread automatically within an object, but instead depends on the specific task relevance of each feature. Here, we employed a novel experimental design, allowing simultaneous electrophysiological measurements of the allocation of attention to two distinct features (rotation and color) within one object (a square) during both trial-wise and block-wise cued shifts of attention. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2019.04.023DOI Listing

Machine learning based hierarchical classification of frontotemporal dementia and Alzheimer's disease.

Neuroimage Clin 2019 Apr 3;23:101811. Epub 2019 Apr 3.

Department of Bio-convergence Engineering, Korea University, Seoul, Republic of Korea; School of Biomedical Engineering, Korea University, Seoul, Republic of Korea. Electronic address:

Background: In a clinical setting, an individual subject classification model rather than a group analysis would be more informative. Specifically, the subtlety of cortical atrophy in some frontotemporal dementia (FTD) patients and overlapping patterns of atrophy among three FTD clinical syndromes including behavioral variant FTD (bvFTD), non-fluent/agrammatic variant primary progressive aphasia (nfvPPA), and semantic variant PPA (svPPA) give rise to the need for classification models at the individual level. In this study, we aimed to classify each individual subject into one of the diagnostic categories in a hierarchical manner by employing a machine learning-based classification method. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101811DOI Listing
April 2019
1 Read

Cardiovascular disease risk factors, tract-based structural connectomics, and cognition in older adults.

Neuroimage 2019 Apr 10;196:152-160. Epub 2019 Apr 10.

Department of Psychology, University of Illinois at Chicago, Chicago, IL, 60607, USA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, 60612, USA; Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL, 60612, USA. Electronic address:

Cardiovascular disease risk factors (CVD-RFs) are associated with decreased gray and white matter integrity and cognitive impairment in older adults. Less is known regarding the interplay between CVD-RFs, brain structural connectome integrity, and cognition. We examined whether CVD-RFs were associated with measures of tract-based structural connectivity in 94 non-demented/non-depressed older adults and if alterations in connectivity mediated associations between CVD-RFs and cognition. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2019.04.024DOI Listing

Trial-by-trial surprise-decoding model for visual and auditory binary oddball tasks.

Neuroimage 2019 Apr 10. Epub 2019 Apr 10.

Department of Electrical Engineering, Sharif University of Technology, Tehran, Iran; imec, Department of Telecommunications and Information Processing, Gent University, Belgium. Electronic address:

Surviving in a continuously changing environment has made the human brain to be able to actively predict the future state of its surroundings. Oddball tasks are specific types of situations during which this nature of the human brain is studied. There are detailed mathematical models which were constructed to explain the brain's perception in these tasks. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10538119193031
Publisher Site
http://dx.doi.org/10.1016/j.neuroimage.2019.04.028DOI Listing
April 2019
1 Read

Talker normalization in typical Cantonese-speaking listeners and congenital amusics: Evidence from event-related potentials.

Neuroimage Clin 2019 Apr 3;23:101814. Epub 2019 Apr 3.

The Hong Kong Polytechnic University, Department of Chinese and Bilingual Studies, Hong Kong, China; Research Centre for Language, Cognition, and Neuroscience, The Hong Kong Polytechnic University, Hong Kong, China. Electronic address:

Despite the lack of invariance in the mapping between the acoustic signal and phonological representation, typical listeners are capable of using information of a talker's vocal characteristics to recognize phonemes, a process known as "talker normalization". The current study investigated the time course of talker normalization in typical listeners and individuals with congenital amusia, a neurodevelopmental disorder of refined pitch processing. We examined the event-related potentials (ERPs) underling lexical tone processing in 24 Cantonese-speaking amusics and 24 typical listeners (controls) in two conditions: blocked-talker and mixed-talker conditions. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101814DOI Listing

CSF glial biomarkers YKL40 and sTREM2 are associated with longitudinal volume and diffusivity changes in cognitively unimpaired individuals.

Neuroimage Clin 2019 Apr 1;23:101801. Epub 2019 Apr 1.

Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain; Alzheimer's Disease and Other Cognitive Disorders Unit, Hospital Clínic, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain; Neurology Department, Hospital Clínic i Provincial de Barcelona, Barcelona, Spain; Universitat Pompeu Fabra, Spain; CIBER Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain. Electronic address:

Cerebrospinal fluid (CSF) YKL40 and sTREM2 are astroglial and microglial activity biomarkers, respectively. We assessed whether CSF YKL40 and sTREM2 baseline levels are associated with longitudinal brain volume and diffusivity changes in cognitively unimpaired adults. Two brain MRI scans of 36 participants (57 to 78-years old, 12 male) were acquired in a 2-year interval. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101801DOI Listing
April 2019
1 Read

Feature-specific prediction errors for visual mismatch.

Neuroimage 2019 Apr 9;196:142-151. Epub 2019 Apr 9.

Translational Neuromodeling Unit (TNU), Institute for Biomedical Engineering, University of Zurich & ETH Zurich, Wilfriedstrasse 6, 8032, Zurich, Switzerland.

Predictive coding (PC) theory posits that our brain employs a predictive model of the environment to infer the causes of its sensory inputs. A fundamental but untested prediction of this theory is that the same stimulus should elicit distinct precision weighted prediction errors (pwPEs) when different (feature-specific) predictions are violated, even in the absence of attention. Here, we tested this hypothesis using functional magnetic resonance imaging (fMRI) and a multi-feature roving visual mismatch paradigm where rare changes in either color (red, green), or emotional expression (happy, fearful) of faces elicited pwPE responses in human participants. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2019.04.020DOI Listing

Category-selective areas in human visual cortex exhibit preferences for stimulus depth.

Neuroimage 2019 Apr 9. Epub 2019 Apr 9.

Department of Psychology, Center for Cognitive & Brain Sciences, The Ohio State University, USA. Electronic address:

Multiple regions in the human brain are dedicated to accomplish the feat of object recognition; yet our brains must also compute the 2D and 3D locations of the objects we encounter in order to make sense of our visual environments. A number of studies have explored how various object category-selective regions are sensitive to and have preferences for specific 2D spatial locations in addition to processing their preferred-stimulus categories, but there is no survey of how these regions respond to depth information. In a blocked functional MRI experiment, subjects viewed a series of category-specific (i. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2019.04.025DOI Listing
April 2019
5 Reads

Decrypting the electrophysiological individuality of the human brain: Identification of individuals based on resting-state EEG activity.

Neuroimage 2019 Apr 9. Epub 2019 Apr 9.

Division Neuropsychology, Institute of Psychology, University of Zurich, Switzerland; University Research Priority Program (URPP) "Dynamic of Healthy Aging", University of Zurich, Switzerland. Electronic address:

Biometric identification (BI) of individuals is a fast-growing field of research that is producing increasingly sophisticated applications in several spheres of everyday life. Previous magnetic resonance imaging (MRI) studies have demonstrated that based on the high inter-individual variability of brain structure and function, it is possible to identify individuals with high accuracy. Otherwise, there is the common belief that electroencephalographic (EEG) data recorded at the surface of the scalp are too noisy for identification purposes with a comparably high hit rate. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2019.04.005DOI Listing
April 2019
2 Reads

The interactive effects of peers and alcohol on functional brain connectivity in young adults.

Neuroimage 2019 Apr 9. Epub 2019 Apr 9.

Temple University, Philadelphia, PA, USA. Electronic address:

Alcohol and peer influence are known to have independent effects on risky decision making. We investigated combined influences of peers and alcohol on functional brain connectivity and behavior. Young adults underwent fMRI while completing response inhibition (Go/No-Go) and risky driving (Stoplight) tasks. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10538119193028
Publisher Site
http://dx.doi.org/10.1016/j.neuroimage.2019.04.003DOI Listing
April 2019
2 Reads

Disentangling the effects of early caregiving experience and heritable factors on brain white matter development in rhesus monkeys.

Neuroimage 2019 Apr 9. Epub 2019 Apr 9.

Department of Psychiatry & Behavioral Sciences, Emory University, Atlanta, GA, USA; Yerkes National Primate Research Center, Emory University, Atlanta, GA, USA.

Early social experiences, particularly maternal care, shape behavioral and physiological development in primates. Thus, it is not surprising that adverse caregiving, such as child maltreatment leads to a vast array of poor developmental outcomes, including increased risk for psychopathology across the lifespan. Studies of the underlying neurobiology of this risk have identified structural and functional alterations in cortico-limbic brain circuits that seem particularly sensitive to these early adverse experiences and are associated with anxiety and affective disorders. Read More

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10538119193029
Publisher Site
http://dx.doi.org/10.1016/j.neuroimage.2019.04.013DOI Listing
April 2019
2 Reads

Hearing-impaired listeners show increased audiovisual benefit when listening to speech in noise.

Neuroimage 2019 Apr 9. Epub 2019 Apr 9.

Cluster of Excellence Hearing4All, Carl von Ossietzky Universität Oldenburg, 26111, Oldenburg, Germany; Neuropsychology Lab, Department of Psychology, School of Medicine and Health Sciences, Carl von Ossietzky Universität Oldenburg, 26111, Oldenburg, Germany; Research Center Neurosensory Science, Carl von Ossietzky Universität Oldenburg, 26111, Oldenburg, Germany.

Recent studies provide evidence for changes in audiovisual perception as well as for adaptive cross-modal auditory cortex plasticity in older individuals with high-frequency hearing impairments (presbycusis). We here investigated whether these changes facilitate the use of visual information, leading to an increased audiovisual benefit of hearing-impaired individuals when listening to speech in noise. We used a naturalistic design in which older participants with a varying degree of high-frequency hearing loss attended to running auditory or audiovisual speech in noise and detected rare target words. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2019.04.017DOI Listing

Phasic alerting effects on visual processing speed are associated with intrinsic functional connectivity in the cingulo-opercular network.

Neuroimage 2019 Apr 9. Epub 2019 Apr 9.

General and Experimental Psychology, Department of Psychology, Ludwig-Maximilians-Universität München, Munich, Germany; Hans-Berger Department of Neurology, University Hospital Jena, Jena, Germany.

Phasic alertness refers to short-lived increases in the brain's "state of readiness", and thus to optimized performance following warning cues. Parametric modelling of whole report task performance based on the computational theory of visual attention (TVA) has demonstrated that visual processing speed is increased in such cue compared to no-cue conditions. Furthermore, with respect to the underlying neural mechanisms, individual visual processing speed has been related to intrinsic functional connectivity (iFC) within the cingulo-opercular network, suggesting that this network's iFC is relevant for the tonic maintenance of an appropriate readiness or alertness state. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2019.04.019DOI Listing

MK-curve - Characterizing the relation between mean kurtosis and alterations in the diffusion MRI signal.

Neuroimage 2019 Apr 10;196:68-80. Epub 2019 Apr 10.

Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Diffusion kurtosis imaging (DKI) is a diffusion MRI (dMRI) technique to quantify brain microstructural properties. While DKI measures are sensitive to tissue alterations, they are also affected by signal alterations caused by imaging artifacts such as noise, motion and Gibbs ringing. Consequently, DKI often yields output parameter values (e. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2019.04.015DOI Listing

The efficacy of transcranial direct current stimulation to prefrontal areas is related to underlying cortical morphology.

Neuroimage 2019 Apr 9;196:41-48. Epub 2019 Apr 9.

School of Psychology, The University of Queensland, St Lucia, 4072, Australia.

Applying a weak electrical current to the cortex can have effects on a range of behaviours. Techniques such as transcranial direct current stimulation (tDCS) have been widely used in both research and clinical settings. However, there is significant variability across individuals in terms of their responsiveness to stimulation, which poses practical challenges to the application of tDCS, but also provides a unique opportunity to study the link between the brain and behaviour. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2019.04.026DOI Listing
April 2019
1 Read

Visual input drives increased occipital responsiveness and harmonized oscillations in multiple cortical areas in migraineurs.

Neuroimage Clin 2019 Apr 3;23:101815. Epub 2019 Apr 3.

Department of Systems Neuroscience, University Medical Center Eppendorf, Hamburg, Germany. Electronic address:

Migraineurs are hypersensitive for most sensory domains like visual, auditory or somatosensory processing even outside of attacks. This behavioral peculiarity is mirrored by findings of cortical hyper-responsivity already in the interictal state. Using repetitive visual stimulation to elicit steady state visually evoked potentials (SSVEP) in 30 interictal episodic migraineurs and 30 controls we show hyper-responsivity of the visual cortex in the migraineurs. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101815DOI Listing

Neural correlates of inhibition and reward are negatively associated.

Neuroimage 2019 Apr 8. Epub 2019 Apr 8.

Department of Psychiatry and Behavioral Neuroscience, MC3077, University of Chicago, 5841 S. Maryland Avenue, Chicago, IL, 60637, USA. Electronic address:

Individuals with impulsive and addictive disorders, including drug addiction, binge eating/obesity, and problem gambling, exhibit both impaired control over behavior and heightened sensitivity to reward. However, it is not known whether such deviation in inhibitory and reward circuitry among clinical populations is a cause or consequence of the disorders. Recent evidence suggests that these constructs may be related at the neural level, and together, increase risk for engaging in maladaptive behaviors. Read More

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2019.04.021DOI Listing
April 2019
1 Read