195 results match your criteria Neuro-Ophthalmic Examination


Value of medical history in ophthalmology: A study of diagnostic accuracy.

J Curr Ophthalmol 2018 Dec 27;30(4):359-364. Epub 2018 Sep 27.

Doheny Eye Institute, University of California Los Angeles, Los Angeles, CA, USA.

Purpose: This study aimed to demonstrate the value of the chief compliant and patient history to accurately diagnose patient pathology without requiring ocular examination or imaging in an outpatient neuro-ophthalmology clinic.

Methods: We prospectively evaluated 115 consecutive patients at our institution from January to April 2009. The attending neuro-ophthalmologist committed to a single most likely diagnosis while solely being exposed to patient demographic information (age, gender, race) and chief complaint, but was otherwise blinded to ocular examination or imaging. Read More

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http://dx.doi.org/10.1016/j.joco.2018.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277212PMC
December 2018

Thickness of the Macula, Retinal Nerve Fiber Layer, and Ganglion Cell-inner Plexiform Layer in the Macular Hole: The Repeatability Study of Spectral-domain Optical Coherence Tomography.

Korean J Ophthalmol 2018 Dec;32(6):506-516

Department of Ophthalmology, Chungnam National University College of Medicine, Daejeon, Korea.

Purpose: We measured the thicknesses of the ganglion cell and inner plexiform layer (GCIPL), the macula, and the retinal nerve fiber layer (RNFL) using spectral-domain optical coherence tomography in patients with idiopathic macula holes to analyze the repeatability of these measurements and compare them with those of the fellow eye.

Methods: We evaluated 85 patients who visited our retinal clinic. The patients were divided into two groups according to their macular hole size: group A had a size of <400 μm, while group B had a size of ≥400 μm. Read More

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https://synapse.koreamed.org/DOIx.php?id=10.3341/kjo.2018.00
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http://dx.doi.org/10.3341/kjo.2018.0030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6288014PMC
December 2018
18 Reads

Acute visual loss and optic disc edema followed by optic atrophy in two cases with deeply buried optic disc drusen: a mimicker of atypical optic neuritis.

BMC Ophthalmol 2018 Oct 26;18(1):278. Epub 2018 Oct 26.

Ocular Oftalmologia, Vitória, Brazil.

Background: Sudden visual loss and optic disc edema caused by optic neuritis (ON) is usually followed by significant visual recovery. However, little or no recovery occurs when the loss is caused by atypical ON, especially in patients with neuromyelitis optica (NMO). Optic disc drusen (ODD) is a cause of pseudo optic disc edema and may be a predisposing factor for non-arteritic anterior ischemic optic neuropathy (NAION), thereby mimicking atypical ON. Read More

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https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12886-018-0949-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6203970PMC
October 2018
9 Reads

Pupillary light reaction in preclinical Alzheimer's disease subjects compared with normal ageing controls.

Br J Ophthalmol 2018 Sep 11. Epub 2018 Sep 11.

Department of Ophthalmology and Visual Sciences, Washington University in St Louis School of Medicine, St. Louis, Missouri, USA.

Background/aims: We wished to determine whether the pupillary light reaction can differentiate preclinical Alzheimer's disease (AD) subjects from normal ageing controls. We performed a prospective study evaluating the pupillary light reaction in a cohort of well-characterised subjects with preclinical AD versus normal ageing controls.

Methods: We recruited 57 subjects from our institution's Memory and Aging Project, part of our Alzheimer's Disease Research Center. Read More

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http://dx.doi.org/10.1136/bjophthalmol-2018-312425DOI Listing
September 2018
3 Reads

Bilateral oculomotor ocular neuromyotonia: a case report.

BMC Neurol 2018 Sep 3;18(1):137. Epub 2018 Sep 3.

Department of Ophthalmology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Bangkok, 10400, Thailand.

Background: Ocular neuromyotonia (ONM) is characterized by episodic diplopia, which is usually triggered by prolonged eccentric gaze of the affected extraocular muscles. The spell is characterized by involuntary, occasionally painful, sustained contraction of one or more extraocular muscles innervated by the oculomotor, trochlear, or abducens nerve. ONM usually occurs as a late consequence of radiotherapy around the parasellar area, although idiopathic cases have been reported. Read More

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https://bmcneurol.biomedcentral.com/articles/10.1186/s12883-
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http://dx.doi.org/10.1186/s12883-018-1142-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6120096PMC
September 2018
14 Reads

Eye damage due to cosmetic ultrasound treatment: a case report.

BMC Ophthalmol 2018 Aug 29;18(1):214. Epub 2018 Aug 29.

Eye Center, Wuhan University Renmin Hospital, 238 Jie Fang Road, Wu Chang District, Wuhan, 430060, China.

Background: Rejuvenation of aging eyelids is one of cosmetic changes to the individual to create the appearance of youth. Tightening treatment of eyelid by ultrasonic heat could possibly develop acute eye injury, including acute increase of IOP, cataract and rarely myopia.

Case Presentation: A case report of rejuvenation tightening treatment caused eye injury with 6 months' follow-up. Read More

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https://bmcophthalmol.biomedcentral.com/articles/10.1186/s12
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http://dx.doi.org/10.1186/s12886-018-0891-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114535PMC
August 2018
27 Reads

[Current diagnosis and treatment of idiopathic intracranial hypertension].

Ideggyogy Sz 2017 Sep;70(9-10):321-332

Országos Klinikai Idegtudományi Intézet, Budapest.

Background And Purpose: Idiopathic intracranial hypertension is cha-racterized by raised intracranial pressure of unknown origin, leading to persisting visual loss if left untreated. Purpose - We assessed timing of surgery, and the efficacy and safety of ventriculo-peritoneal shunt.

Methods: Retrospective analysis of 65 patients treated at our Neuro-ophthalmology Clinic between 2009 and 2017. Read More

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http://dx.doi.org/10.18071/isz.70.0321DOI Listing
September 2017
3 Reads

Vertical diplopia and oscillopsia due to midbrain keyhole aqueduct syndrome associated with severe cough.

Am J Ophthalmol Case Rep 2018 Jun 15;10:128-131. Epub 2018 Feb 15.

Department of Ophthalmology, Stanford School of Medicine, 2452 Watson Court, Palo Alto, CA 94303-5353, USA.

Purpose: Midline structural defects in the neural axis can give rise to neuro-ophthalmic symptoms. We report a rare case of keyhole aqueduct syndrome presenting after two years of severe cough due to gastroesophageal reflux disease.

Observations: A 58-year-old woman with a 2-year history of daily, severe cough presented to the neuro-ophthalmology clinic with progressive diplopia and oscillopsia. Read More

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http://dx.doi.org/10.1016/j.ajoc.2018.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910451PMC
June 2018
5 Reads

An atypical case of neurosarcoidosis presenting with neovascular glaucoma.

J Ophthalmic Inflamm Infect 2018 Apr 18;8(1). Epub 2018 Apr 18.

Department of Ophthalmology, University Hospital Ghent, De Pintelaan 185, 9000, Ghent, Belgium.

Background: Sarcoidosis, a multisystem, granulomatous disorder, sometimes manifests with a neuro-ophthalmic subtype. The latter can pose a diagnostic challenge, especially when ocular symptoms appear before systemic involvement, as the clinical picture then can be non-specific and systemic laboratory and standard imaging investigations can be negative.

Findings: A 71-year-old woman presented with a 4-month history of sudden-onset visual loss in the left eye. Read More

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https://joii-journal.springeropen.com/articles/10.1186/s1234
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http://dx.doi.org/10.1186/s12348-018-0149-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906415PMC
April 2018
4 Reads

Automated achromatic perimetry.

Oman J Ophthalmol 2018 Jan-Apr;11(1):3-10

Department of Glaucoma and Anterior Segment, Regional Institute of Ophthalmology (RIO), Government Medical College, Amritsar, Punjab, India.

Visual field (VF) testing is an important diagnostic tool for Glaucoma. The current gold standard for VF testing is automated perimetry. This article is an attempt to familiarize the reader with components of an achromatic (white on white) automated perimetry printout. Read More

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http://dx.doi.org/10.4103/ojo.OJO_28_2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5848344PMC
March 2018
1 Read

Correlations among multifocal electroretinography and optical coherence tomography findings in patients with Parkinson's disease.

Neurol Sci 2018 Mar 18;39(3):533-541. Epub 2018 Jan 18.

School of Medicine, Ophthalmology Department, Erciyes University, 38039, Kayseri, Turkey.

To assess the correlation between functional and anatomical evaluations with multifocal electroretinography (mfERG) and spectral-domain optical coherence tomography (SD-OCT) in patients with Parkinson's disease (PD). This cross-sectional study involved 116 eyes of 58 patients with PD and 30 age- and sex-matched control subjects. All study participants underwent a comprehensive neuro-ophthalmic examination, retinal single-layer thicknesses and volumes, and peripapillary retinal nerve fiber layer (pRNFL) measurements with SD-OCT, and the patients' mfERG recordings were evaluated. Read More

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http://dx.doi.org/10.1007/s10072-018-3244-2DOI Listing
March 2018
4 Reads

Retinitis Pigmentosa Sine Pigmento Mimicking a Chiasm Disease.

Neuroophthalmology 2017 Aug 15;41(4):198-201. Epub 2017 Mar 15.

Neuro-Ophthalmology Service, Department of Ophthalmology, Conegliano Hospital, Conegliano (TV), Italy.

A 75-year-old woman presented to her ophthalmologist complaining of visual loss for several years. The ophthalmic examination was remarkable for a bitemporal visual field defect. Magnetic resonance imaging (MRI) scan of the brain was normal without evidence of chiasm compression. Read More

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http://dx.doi.org/10.1080/01658107.2017.1292532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762150PMC
August 2017
15 Reads

Reversal of carotid dissection-induced ocular and cerebral ischemia by stenting.

Am J Ophthalmol Case Rep 2017 Sep 18;7:50-54. Epub 2017 May 18.

Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan, United States.

Purpose: To present an example of how close clinical monitoring of a patient with acute Horner syndrome from carotid artery dissection may be critical in reversing neurologic dysfunction.

Observations: A patient whose initial neuro-ophthalmic manifestation was Horner syndrome, but who evolved over 14 days to display transient monocular vision loss, ipsilateral ocular ischemic syndrome, and episodic contralateral hemiparesis. Digital subtraction angiography demonstrated progressive ipsilateral carotid occlusion with lack of collateral flow. Read More

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http://dx.doi.org/10.1016/j.ajoc.2017.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722172PMC
September 2017
4 Reads

Eye movement abnormalities in AQP4-IgG positive neuromyelitis optica spectrum disorder.

J Neurol Sci 2018 Jan 24;384:91-95. Epub 2017 Nov 24.

Department of Neurology, Beijing Tongren Hospital, Capital Medical University, Beijing, China. Electronic address:

Background And Purpose: Neuromyelitis optica spectrum disorder (NMOSD) has been recognized as a disease characterized by severe visual afferent impairment. Abnormal eye movements, as the other important neuro-ophthalmic manifestation of NMOSD, were commonly overlooked. The aim of our study was to describe the ocular motor manifestations of AQP4-IgG positive NMOSD patients, and explore the value of eye movement abnormalities in the evaluation of the disabled disease. Read More

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http://dx.doi.org/10.1016/j.jns.2017.11.033DOI Listing
January 2018
6 Reads

Optical Coherence Tomography in the Management of Skull Base Fibrous Dysplasia with Optic Nerve Involvement.

World Neurosurg 2018 Jan 13;109:e546-e553. Epub 2017 Oct 13.

Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, New York, New York, USA; Department of Otolaryngology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Background: Fibrous dysplasia (FD) of the skull base can manifest with optic nerve compression. As most patients initially do not experience vision loss, controversy exists whether to proceed with prophylactic surgical decompression or elect for conservative observation. Optical coherence tomography (OCT), a physiologic imaging modality widely used to assess the condition of the retinal nerve fiber layer (RNFL), has been useful in monitoring compressive tumors on the optic nerve. Read More

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http://dx.doi.org/10.1016/j.wneu.2017.10.018DOI Listing
January 2018
13 Reads

Neuro-ophthalmology in the Horse.

Authors:
Kathern E Myrna

Vet Clin North Am Equine Pract 2017 Dec 27;33(3):541-549. Epub 2017 Sep 27.

Department of Small Animal Medicine and Surgery, Veterinary Medical Center, University of Georgia, 2200 College Station Road, Athens, GA 30602, USA. Electronic address:

This article provides a brief, clinically relevant review of neurologic disorders of the eye. A description of the neuro-ophthalmic examination is provided. Stepwise descriptions of the most common neuro-ophthalmic abnormalities are provided along with common rule outs. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S07490739173087
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http://dx.doi.org/10.1016/j.cveq.2017.07.001DOI Listing
December 2017
3 Reads

Eye changes among HIV positive patients on antiretroviral therapy in Nepal.

Nepal J Ophthalmol 2016 01;8(15):62-70

Objective: To find out eye findings among HIV positive patients in the era of antiretroviral therapy. Method This Hospital based cross sectional descriptive study was carried at B. P. Read More

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http://dx.doi.org/10.3126/nepjoph.v8i1.16158DOI Listing
January 2016
1 Read

Delayed and isolated oculomotor nerve palsy following minor head trauma.

Surg Neurol Int 2017 6;8:20. Epub 2017 Feb 6.

Department of Neurosurgery, School of Medicine, Keio University, Tokyo, Japan.

Background: The purpose of this study was to consider the mechanism of isolated oculomotor nerve palsy after minor head trauma.

Case Description: We report a rare case of delayed and isolated oculomotor nerve palsy following minor head trauma. A 19-year-old boy complained of double vision 1 day after a minor head trauma. Read More

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http://dx.doi.org/10.4103/2152-7806.199556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5309438PMC
February 2017
5 Reads

A Rare Case of Unilateral Progressive Vision Loss and Pachymeningitis.

Neuroophthalmology 2016 Oct 11;40(5):237-242. Epub 2016 Aug 11.

Department of Neurology, University of Illinois College of Medicine, Peoria, Peoria, Illinois, USA; Illinois Neurologic Institute, Peoria, Illinois, USA.

We describe a 32-year-old man with presumed Vogt-Koyanagi Harada (VKH) syndrome, whose presenting symptoms were headache and progressive loss of vision in the right eye. Neuro-ophthalmic examination showed anterior and posterior uveitis, and retinal detachment in the right eye. Ocular coherence tomography (OCT) showed extensive submacular fluid in the right eye, while the fundus fluorescein angiogram (FFA) confirmed perifoveal retinal pigment epithelium (RPE) disruption and multifocal fluorescein leakage in the right eye. Read More

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http://dx.doi.org/10.1080/01658107.2016.1212079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5123095PMC
October 2016
26 Reads

Abnormal eye movement behavior during reading in Parkinson's disease.

Parkinsonism Relat Disord 2016 11 12;32:130-132. Epub 2016 Aug 12.

Department of Ophthalmology, Stanford University School of Medicine, Stanford, CA, USA. Electronic address:

Introduction: Reading difficulties are common in Parkinson's disease (PD) but not well studied. We report a case of reading difficulties in a 40-year-old man with 6-year history of PD on dopamine replacement therapy.

Methods: We performed detailed neuro-ophthalmic examination and assessment of reading with and without infrared oculography. Read More

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http://dx.doi.org/10.1016/j.parkreldis.2016.08.008DOI Listing
November 2016
3 Reads

Horizontal Gaze Palsy and Progressive Scoliosis With ROBO 3 Mutations in Patients From Cape Verde.

J Neuroophthalmol 2017 06;37(2):162-165

Garcia de Orta Hospital, Almada, Portugal.

Horizontal gaze palsy with progressive scoliosis (HGPPS) is a rare and autosomal recessive syndrome. We describe 2 cases of HGPPS which are the first documented in patients of African ancestry from an isolated population in Cape Verde. They demonstrated typical findings on neuro-ophthalmic examination and brain magnetic resonance imaging. Read More

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http://dx.doi.org/10.1097/WNO.0000000000000455DOI Listing
June 2017
4 Reads

Overlap of Myasthenia Gravis and Miller Fisher Syndrome.

Intern Med 2016 15;55(14):1917-8. Epub 2016 Jul 15.

Department of Neurology, Gifu Municipal Hospital, Japan.

In this case report, we describe a patient with myasthenia gravis (MG) and Miller Fisher syndrome (MFS) overlap. A 69-year-old woman presented with acute bilateral ptosis, ophthalmoplegia, ataxic gait, and areflexia. The MFS diagnosis was confirmed with by a positive anti-GQ1b IgG antibody test result. Read More

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http://dx.doi.org/10.2169/internalmedicine.55.6262DOI Listing
March 2017
16 Reads

The indications for and the diagnostic yield of imaging in neuro-ophthalmic and orbital disorders.

Nepal J Ophthalmol 2015 Jul;7(14):159-63

Unlabelled: Correction: On 7th June, the first author's name was changed FROM Eli Ranjitkar Pradan TO Eli Pradhan Introduction: Neuro-imaging is an important method of investigation in neuro- ophthalmic and orbital conditions. These investigations are expensive and time consuming. This study describes the diagnostic yield of neuroimaging in patients referred from neuro-ophthalmic services. Read More

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http://dx.doi.org/10.3126/nepjoph.v7i2.14966DOI Listing
July 2015
1 Read

[A rare cause of optic neuropathy: Cassava].

J Fr Ophtalmol 2016 Jun 25;39(6):506-14. Epub 2016 May 25.

Service d'ophtalmologie 3, Centre hospitalier national d'ophtalmologie des Quinze-Vingts, université de Versailles Saint-Quentin-en-Yvelines, 28, rue de Charenton, 75012 Paris, France; Service d'ophtalmologie, hôpital Ambroise-Paré, AP-HP, université de Versailles Saint-Quentin-en-Yvelines, 9, avenue Charles-De-Gaulle, 92100 Boulogne-Billancourt, France; Inserm, U968, université UPMC Paris VI, UMR S 968, Institut de la vision, CNRS, UMR 7210, 75012 Paris, France.

Introduction: Cassava root is a staple food for almost 500 million people worldwide. Excessive consumption of it is a rare cause of optic neuropathy.

Method: Ten patients diagnosed with cassava root related optic neuropathy were included in this retrospective study. Read More

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http://dx.doi.org/10.1016/j.jfo.2016.02.009DOI Listing
June 2016
12 Reads

Neuro-Ophthalmology of Space Flight.

J Neuroophthalmol 2016 Mar;36(1):85-91

Department of Ophthalmology (AGL, CRB), Houston Methodist Hospital, Houston, Texas; Department of Ophthalmology (AGL), Baylor College of Medicine, Houston, Texas; Departments of Ophthalmology, Neurology, and Neurosurgery (AGL), Weill Cornell Medical College, New York, New York; Department of Ophthalmology (AGL), The University of Texas Medical Branch, Galveston, Texas; Department of Ophthalmology (AGL), The University of Iowa Hospitals and Clinics, Iowa City, Iowa; Section of Ophthalmology (AGL), The University of Texas MD Anderson Cancer Center, Houston, Texas; Space Medicine Division (WJT, SFH), National Aeronautics and Space Administration, Washington, DC; US Army (THM), Cooper Landing, Alaska; Coastal Eye Associates (CRG), Webster, Texas; and Universities Space Research Association (CO), National Aeronautics and Space Administration, Washington, DC.

Background: To describe the history, clinical findings, and possible pathogenic etiologies of the constellation of neuro-ophthalmic findings discovered in astronauts after long-duration space flight and to discuss the terrestrial implications of such findings.

Evidence Acquisition: Retrospective review of published observational, longitudinal examination of neuro-ophthalmic findings in astronauts after long-duration space flight; analysis of postflight questionnaires regarding in-flight vision changes in approximately 300 additional astronauts; and hypothesis generating for developing possible future countermeasures and potential implications for neuro-ophthalmic disorders on Earth. Astronauts with neuro-ophthalmic findings, which were not present at the start of a space flight mission and only seen on return from long-duration space missions to the International Space Station, will be discussed. Read More

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http://pdfs.journals.lww.com/jneuro-ophthalmology/2016/03000
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/WNO.0000000000000334DOI Listing
March 2016
30 Reads

A rare manifestation of neuro-ophthalmic sarcoidosis: A case report.

Taiwan J Ophthalmol 2016 Jan-Mar;6(1):45-51. Epub 2015 Apr 3.

Department of Ophthalmology, Tri-Service General Hospital and National Defense Medical Center, Taipei, Taiwan.

Purpose: Anterior uveitis is the most common ocular manifestation of sarcoidosis. Ocular involvement affects approximately 30-60% of patients with systemic sarcoidosis; however, optic disc edema is a rare event. We report a patient who presented with a rare case of sarcoidosis with neuro-ophthalmic manifestations. Read More

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http://dx.doi.org/10.1016/j.tjo.2015.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5602126PMC
April 2015
6 Reads

[Neuro-ophthalmic adverse effects of metronidazole treatment in children: Two case studies].

Arch Pediatr 2016 Feb 14;23(2):167-70. Epub 2015 Dec 14.

Service d'ophtalmologie B, institut Hédi-Rais, boulevard 9-avril, 1006 Tunis, Tunisie.

Purpose: To report the onset of neuro-ophthalmological adverse effects in two children treated with metronidazole for amoebic dysentery.

Observations: A 6-year-old child and his 8-year-old sister presented with sudden bilateral vision loss and diplopia associated with intense headache and vomiting. The medical history revealed amoebic dysentery 3 weeks before treated orally with metronidazole for 2 weeks. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0929693X150042
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http://dx.doi.org/10.1016/j.arcped.2015.11.003DOI Listing
February 2016
5 Reads

Pitfalls in the Use of Stereoacuity in the Diagnosis of Nonorganic Visual Loss.

Ophthalmology 2016 Jan 16;123(1):198-202. Epub 2015 Oct 16.

Department of Ophthalmology, Emory University, Atlanta, Georgia; Department of Neurology, Emory University, Atlanta, Georgia; Department of Epidemiology, Emory University, Atlanta, Georgia. Electronic address:

Purpose: The Titmus Stereotest (Stereo Optical Co., Inc., Chicago, IL) has been used to estimate visual acuity (VA) in the evaluation of nonorganic visual loss. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01616420150105
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http://dx.doi.org/10.1016/j.ophtha.2015.09.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695302PMC
January 2016
3 Reads

Vision related quality of life in spinocerebellar ataxia.

J Neurol Sci 2015 Nov 9;358(1-2):404-8. Epub 2015 Oct 9.

Department of Neurology and the McKnight Brain Institute, University of Florida College of Medicine, Gainesville, FL, USA. Electronic address:

Objective: Spinocerebellar ataxia (SCA) leads to abnormal ocular motility and alignment. The objective of this study was to quantitatively assess vision, ocular motility and alignment and its impact on vision related quality of life (VRQOL) in SCA.

Methods: Nineteen genetically diagnosed SCA subjects (11 SCA type 3, 3 SCA type 1 and 5 SCA type 6) participated at two university centers. Read More

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http://dx.doi.org/10.1016/j.jns.2015.10.013DOI Listing
November 2015
3 Reads

The Concussion Toolbox: The Role of Vision in the Assessment of Concussion.

Semin Neurol 2015 Oct 6;35(5):599-606. Epub 2015 Oct 6.

Department of Neurology, New York University School of Medicine, New York, New York.

Concussion may lead to subtle changes in brain function, and tests involving the visual system probe higher cortical functioning and increase our sensitivity in detecting these changes. Concussions are acutely and sometimes more persistently associated with abnormalities in balance, cognition, and vision. The visual system involves roughly half of the brain's circuits, including many regions susceptible to head impacts. Read More

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https://www.thieme-connect.com/products/ejournals/pdf/10.105
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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0035-1563567
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http://dx.doi.org/10.1055/s-0035-1563567DOI Listing
October 2015
6 Reads

Optic disc drusen demonstrate a hyperechogenic artifact in B mode ultrasound.

J Clin Neurosci 2016 Jan 26;23:111-119. Epub 2015 Sep 26.

Department of Ophthalmology, Meir Medical Center, 59 Tschernihovsky St., Kfar Sava 44281, Israel. Electronic address:

We describe a new, specific, hyperechogenic artifact spot in B-mode ultrasound (US) in patients diagnosed with optic nerve drusen (OND). This is a retrospective chart review of 34 consecutive patients with OND using B-scan US. The patients underwent full ophthalmic evaluation and neuro-ophthalmic examination. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S09675868150042
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http://dx.doi.org/10.1016/j.jocn.2015.08.005DOI Listing
January 2016
9 Reads

Factors affecting visual loss and visual recovery in patients with pseudotumor cerebri syndrome.

Arq Bras Oftalmol 2015 May-Jun;78(3):175-9

Department of Ophthalmology, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.

Purpose: To investigate the frequency of visual loss (VL), possible predictive factors of VL, and improvement in patients with pseudotumor cerebri (PTC) syndrome.

Methods: We reviewed 50 PTC patients (43 females, seven males) who underwent neuro-ophthalmic examination at the time of diagnosis and after treatment. Demographic data, body mass index (BMI), time from symptom onset to diagnosis (TD), maximum intracranial pressure (MIP), occurrence of cerebral venous thrombosis (CVT), and treatment modalities were reviewed. Read More

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http://dx.doi.org/10.5935/0004-2749.20150045DOI Listing
December 2015
3 Reads

[First case described of isolated, complete and fluctuating cranial nerve III palsy heralding multiple myeloma].

Rev Neurol 2015 Feb;60(3):115-9

Hospital Universitario Principe de Asturias, 28805 Alcala de Henares, Espana.

Introduction: Multiple myeloma is the most common plasma-cell malignancy. To be incurable, treatment aims to obtain the longest non-clinical survival time. Cranial nerve palsy in multiple myeloma is extremely rare and is usually due to an intracranial plasmacytoma. Read More

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February 2015
3 Reads

The ophthalmologic signs in case of C1 neurinoma without hydrocephalus - case report.

Pomeranian J Life Sci 2015 ;61(3):278-81

Introduction: We present a case of the patient suffering from the tumor of cranio-spinal junction in whom a wide spectrum of ophthalmic and neuroophtalmic signs was noted.

Methods: The comprehensive neuro-ophthalmic examination were performed (pupillary reactions, visual activity, fundus ophthalmoloscopy, intraocular pressures, eye movements, visual field, MRI, MR angiography). Additionally immunohistochemistry and laboratory tests were made. Read More

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July 2016
4 Reads

Neuro-ophthalmic presentation and surgical results of unruptured intracranial aneurysms—prospective Helsinki experience of 142 patients.

World Neurosurg 2015 Apr 18;83(4):614-9. Epub 2014 Dec 18.

Department of Neurosurgery, Helsinki University Central Hospital, Helsinki, Finland.

Objective: To assess prospectively neuro-ophthalmic findings associated with unruptured intracranial aneurysms and treatment morbidity and to identify factors predicting these findings.

Methods: Patients admitted to Helsinki University Central Hospital and treated surgically or endovascularly during 2011 underwent a neuro-ophthalmic examination, including formal visual field testing, before operation, at discharge, and 2-4 months and ≥6 months postoperatively. Univariate and multivariate analysis was used to identify factors predicting eye movement disorders. Read More

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http://dx.doi.org/10.1016/j.wneu.2014.12.017DOI Listing
April 2015
19 Reads
2.420 Impact Factor

The multiple sclerosis visual pathway cohort: understanding neurodegeneration in MS.

BMC Res Notes 2014 Dec 15;7:910. Epub 2014 Dec 15.

Center of Neuroimmunology, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) - Hospital Clinic of Barcelona, Casanova 145, Planta 3A, 08036 Barcelona, Spain.

Background: Multiple Sclerosis (MS) is an immune-mediated disease of the Central Nervous System with two major underlying etiopathogenic processes: inflammation and neurodegeneration. The latter determines the prognosis of this disease. MS is the main cause of non-traumatic disability in middle-aged populations. Read More

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http://dx.doi.org/10.1186/1756-0500-7-910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300678PMC
December 2014
26 Reads

Ocular manifestations in a child with systemic brucellosis.

J Res Med Sci 2014 Jul;19(7):677-9

Isfahan Eye Research Center, Feiz Hospital, Isfahan University of Medical Sciences, Isfahan, Iran.

Brucellosis is a zoonotic disease with widespread prevalence. It presents with in various range and often with the presence of non-specific clinical signs and symptoms. Brucellosis also may cause different manifestations in eyes such as uveitis, keratitis, conjunctivitis and neuro-ophthalmic defects. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4214029PMC
July 2014
7 Reads

The King-Devick (K-D) test of rapid eye movements: a bedside correlate of disability and quality of life in MS.

J Neurol Sci 2014 Aug 2;343(1-2):105-9. Epub 2014 Jun 2.

Department of Neurology, New York University School of Medicine, New York, NY, United States; Department of Population Health, New York University School of Medicine, New York, NY, United States. Electronic address:

Objective: We investigated the King-Devick (K-D) test of rapid number naming as a visual performance measure in a cohort of patients with multiple sclerosis (MS).

Methods: In this cross-sectional study, 81 patients with MS and 20 disease-free controls from an ongoing study of visual outcomes underwent K-D testing. A test of rapid number naming, K-D requires saccadic eye movements as well as intact vision, attention and concentration. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S0022510X140035
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http://dx.doi.org/10.1016/j.jns.2014.05.047DOI Listing
August 2014
17 Reads

Eye movement abnormalities after a ruptured intracranial aneurysm.

World Neurosurg 2015 Mar 19;83(3):362-7. Epub 2014 Apr 19.

Department of Neurosurgery, Helsinki University Central Hospital, Helsinki, Finland.

Objective: Overlooking eye movement abnormalities associated with aneurysmal subarachnoid hemorrhage (aSAH) is common, although these abnormalities may greatly affect quality of life. Their prevalence remains undetermined. The aim of the study was to assess preoperative and postoperative eye movement abnormalities and their recovery in follow-up of patients with aSAH and their association with age, gender, and aSAH severity. Read More

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http://dx.doi.org/10.1016/j.wneu.2014.04.059DOI Listing
March 2015
11 Reads
1 Citation
2.420 Impact Factor

Quantification of peripapillary total retinal volume in pseudopapilledema and mild papilledema using spectral-domain optical coherence tomography.

Am J Ophthalmol 2014 Jul 12;158(1):136-43. Epub 2014 Apr 12.

Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, Maryland. Electronic address:

Purpose: To distinguish differences in retinal nerve fiber layer (RNFL) thickness and peripapillary total retinal volume between eyes with papilledema, pseudopapilledema, and normal findings.

Design: Cohort study.

Methods: Forty-two eyes with mild papilledema, 37 eyes with congenitally elevated optic disc (pseudopapilledema), and 34 normal eyes met the inclusion criteria at 1 academic institution (in Iran) and underwent neuro-ophthalmic examination. Read More

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http://dx.doi.org/10.1016/j.ajo.2014.03.008DOI Listing
July 2014
7 Reads

Trial end points and natural history in patients with G11778A Leber hereditary optic neuropathy : preparation for gene therapy clinical trial.

JAMA Ophthalmol 2014 Apr;132(4):428-36

Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida.

IMPORTANCE Establishing the natural history of G11778A Leber hereditary optic neuropathy (LHON) is important to determine the optimal end points to assess the safety and efficacy of a planned gene therapy trial. OBJECTIVE To use the results of the present natural history study of patients with G11778A LHON to plan a gene therapy clinical trial that will use allotopic expression by delivering a normal nuclear-encoded ND4 gene into the nuclei of retinal ganglion cells via an adeno-associated virus vector injected into the vitreous. DESIGN, SETTING, AND PARTICIPANTS A prospective observational study initiated in 2008 was conducted in primary and referral institutional practice settings. Read More

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http://dx.doi.org/10.1001/jamaophthalmol.2013.7971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4266137PMC
April 2014
13 Reads

Neuro-ophthalmic disorders in pregnancy.

Continuum (Minneap Minn) 2014 Feb;20(1 Neurology of Pregnancy):162-76

Purpose Of Review: This review discusses evaluation and treatment of neuro-ophthalmic disorders in the pregnant patient.

Recent Findings: Any neuro-ophthalmic abnormality seen in nonpregnant women can be seen in pregnant women. Pregnancy-specific complications (preeclampsia and eclampsia) cause visual symptoms and can affect the entire visual axis. Read More

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http://dx.doi.org/10.1212/01.CON.0000443843.25686.62DOI Listing
February 2014
8 Reads

Optic nerve cupping and the neuro-ophthalmologist.

J Neuroophthalmol 2013 Dec;33(4):377-89

Save Sight Institute (CLF, AJRW), University of Sydney, Sydney, Australia; Westmead Millennium Institute (AJRW), University of Sydney, Sydney, Australia; Moorfields Eye Hospital (GTP), London, United Kingdom; and Cambridge University Teaching Hospitals NHS Foundation Trust (KRM), Cambridge, United Kingdom.

Background: While glaucoma is the most common cause of optic disc cupping, it can also be seen in a number of congenital and acquired optic neuropathies. It behooves both glaucoma and neuro-ophthalmic specialists to be able to differentiate glaucoma from neurological conditions, which give a similar ophthalmoscopic appearance to the optic disc.

Evidence Acquisition: This review is a combination of the authors' clinical experience from tertiary glaucoma and neuro-ophthalmology referral centers, combined with a literature review using PubMed. Read More

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http://pdfs.journals.lww.com/jneuro-ophthalmology/2013/12000
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/WON.0000000000000080DOI Listing
December 2013
5 Reads

Visual quality of life in veterans with blast-induced traumatic brain injury.

JAMA Ophthalmol 2013 Dec;131(12):1602-9

Ophthalmology Service, VA Palo Alto Health Care System, Palo Alto, California4Department of Ophthalmology, Stanford University School of Medicine, Palo Alto, California.

Importance: Traumatic brain injury (TBI) is an important cause of morbidity worldwide, with increasing awareness of the role of blast exposure in military and civilian casualties. Visual problems have been reported in TBI and may affect functioning and quality of life.

Objective: To evaluate the 25-item National Eye Institute Visual Functioning Questionnaire and Neuro-Ophthalmic Supplement for utility in assessing the effect of blast exposure on perceived visual functioning among veterans with TBI. Read More

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http://mldc.whs.mil/public/docs/library/131021_BVA_Visual_Qu
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http://archopht.jamanetwork.com/article.aspx?doi=10.1001/jam
Publisher Site
http://dx.doi.org/10.1001/jamaophthalmol.2013.5028DOI Listing
December 2013
2 Reads

[Clinical practice guideline for the diagnosis and treatment of pituitary apoplexy].

Endocrinol Nutr 2013 Dec 14;60(10):582.e1-582.e12. Epub 2013 Sep 14.

Servicio de Endocrinología y Nutrición, Hospital Virgen de la Salud, Complejo Hospitalario de Toledo, Toledo, España. Electronic address:

Unlabelled: Classic pituitary apoplexy (PA) is an acute, life-threatening clinical syndrome caused by acute hemorrhage and/or infarction of the pituitary gland. PA is considered a neuroendocrinological emergency. However, there is no consensus about the best options for PA diagnosis and management. Read More

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http://dx.doi.org/10.1016/j.endonu.2013.04.013DOI Listing
December 2013
19 Reads

[Ocular and neuro-ophthalmic manifestations of sarcoidosis: retrospective study of 30 cases].

J Fr Ophtalmol 2013 Jun 29;36(6):473-80. Epub 2013 Mar 29.

Service d'ophtalmologie, CHRU de Tours, boulevard Tonnellé, 37000 Tours, France.

Introduction: The purpose of this study was to describe the diagnostic strategy and therapeutic approach when sarcoidosis of the visual pathways is suspected, by way of a descriptive study of sarcoidosis patients in the ophthalmology services in Tours, Rennes and Angers.

Patients And Methods: A multicenter, retrospective chart review was performed for 30 patients diagnosed with sarcoidosis and followed at the university hospitals of Tours, Rennes and Angers between January 1997 and August 2011. The diagnosis of sarcoidosis was based on a combination of clinical and ancillary tests, including pathologic confirmation and/or hyperlymphocytosis with a CD4/CD8 ratio greater than 5 on bronchoalveolar lavage. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01815512130005
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http://dx.doi.org/10.1016/j.jfo.2012.06.029DOI Listing
June 2013
3 Reads

Ocular Manifestations in Patients with HIV Infection/AIDS who were Referred from the ART Centre, Hassan, Karnataka, India.

J Clin Diagn Res 2012 Dec 6;6(10):1756-60. Epub 2012 Oct 6.

Senior Resident, Department of Ophthalmology, Hassan Institute Of Medical Sciences , Hassan, Karnataka, India.

Background: Ocular involvement in HIV infection/AIDS is very common and it includes various clinical presentations which may be asymptomatic or atypical or they may be the initial manifestations of the underlying disease. The severity of these lesions increases as the immune competency decreases, leading to visual impairment or blindness.

Objective: The purpose of this study was to determine the prevalence and the types of HIV associated ocular conditions and their effect on the vision in patients with HIV/AIDS. Read More

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http://dx.doi.org/10.7860/JCDR/2012/4738.2637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3552221PMC
December 2012
3 Reads

Clinical features and pathophysiological mechanism of the hemianoptic complication after the occipital transtentorial approach.

Clin Neurol Neurosurg 2013 Aug 20;115(8):1250-6. Epub 2012 Dec 20.

Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Objective: To obtain detailed insight into neuro-ophthalmological characteristics and pathophysiology of hemianoptic complications after occipital transtentorial surgery.

Methods: We reviewed the cases of 14 patients surgically treated by the occipital transtentorial approach. Treated lesions included 6 posterior third ventricle tumors, including pineal and tectal lesions, 3 falco-tentorial meningiomas, and 5 superior cerebellar lesions. Read More

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http://dx.doi.org/10.1016/j.clineuro.2012.11.024DOI Listing
August 2013
12 Reads

Ocular manifestations (strabismus: duane syndrome; and retinal nerve fiber hypoplasia) in okihiro syndrome (duane radial ray syndrome).

Binocul Vis Strabolog Q Simms Romano 2012 ;27(4):235-42

Background And Purpose: Two siblings diagnosed with Okihiro Syndrome (also named Duane Radial Ray Syndrome) associated with ophthalmic manifestation including Duane Syndrome and retinal nerve fiber layer (RNFL) hypoplasia were presented.

Methods: The first patient (15-years old female) was diagnosed of Duane Syndrome presenting reduction of visual acuity and pale optic discs. She showed a diffuse decrease in the RNFL thickness, mainly in her left eye, retaining the typical RNFL morphology as double hump, demonstrated by OCT and scanning laser polarimetry. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856715PMC
April 2016
8 Reads

Miller Fisher syndrome mimicking ocular myasthenia gravis.

Optom Vis Sci 2012 Dec;89(12):e118-23

Optometry Clinic Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, Ohio 44106, USA.

PURPOSE.: Miller Fisher syndrome (MFS) is a rare immune-mediated neuropathy that commonly presents with diplopia after the acute onset of complete bilateral external ophthalmoplegia. Ophthalmoplegia is often accompanied by other neurological deficits such as ataxia and areflexia that characterize MFS. Read More

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http://dx.doi.org/10.1097/OPX.0b013e31827717c1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516407PMC
December 2012
35 Reads