2,623 results match your criteria Neuro endocrinology letters[Journal]


Evaluation of the effectiveness of treatment of vulvar lichen sclerosus et atrophicus. Analysis of own material and review of the literature.

Neuro Endocrinol Lett 2018 Dec 22;39(5):417-421. Epub 2018 Dec 22.

1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Pl. Starynkiewicza 1-3, 02-015 Warsaw, Poland.

Material And Methods: The study group included eleven female patients aged 18-77 years with a diagnosis of lichen sclerosus. Basic therapy consisted in the application of clobetasol in the first month and then once a day for the following two months. Then, clobetasol was recommended once a week until full resolution of the symptoms. Read More

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December 2018
4 Reads

Selected bisphenols and phthalates screened for estrogen and androgen disruption by in silico and in vitro methods.

Neuro Endocrinol Lett 2018 Dec 22;39(5):409-416. Epub 2018 Dec 22.

Charles University in Prague, Third Faculty of Medicine, Ruská 87, Prague, Czech Republic.

Objectives: The aim of this study was to detect endocrine disruption potential of selected bisphenols and phthalates, compare in silico prediction with results from two in vitro methods and bring up-to-date information on development of EU legislation, available in vitro methods and biomechanisms involved in endocrine disruption.

Material And Methods: In silico approach based on the OECD QSAR Toolbox was used for prediction of estrogen receptor α binding. OECD TG 455 assay and a yeast-based YES/YAS assay was used to determine the interactions with human estrogen (ERα) and androgen receptors. Read More

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December 2018
6 Reads

Assessing the awareness of Czechs, age 40+, on the link between lifestyle choices and risk factors for cardiovascular diseases.

Neuro Endocrinol Lett 2018 Dec 22;39(5):401-408. Epub 2018 Dec 22.

Institute for Clinical and Experimental Medicine, Department of Preventive Cardiology, Prague, Czech Republic.

Objectives: Cardiovascular diseases constitute the main cause of disability and premature death worldwide. Those diseases will continue to endanger health unless the public understands clearly and completely which risk factors contribute to the development of these diseases and what they can do to avoid these risks. This article assesses the understanding of risk factors that can lead to the development of heart and vessel diseases. Read More

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December 2018
3 Reads

Mathematical evaluation of melatonin secretion in hypoxic ischemic encephalopathy.

Neuro Endocrinol Lett 2018 Dec 22;39(5):391-400. Epub 2018 Dec 22.

Department of Medical Physics, Maria Skłodowska- Curie Memorial Cancer Center and Institute of Oncology Gliwice Branch, Poland.

Objectives: The aims of the study were to assess the kinematics of the lower limbs and pelvis during normal walking in professional ballet dancers and to investigate relationships between movements of segments of the lower limbs and pelvis.

Methods: Thirty one professional ballet dancers and twenty eight controls completed five walking trials at their preferred speed. Kinematic data in the basic anatomical planes for ankle, knee, and hip joints as well as for the pelvis were collected with an optoelectronic motion system. Read More

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December 2018
4 Reads

Comparison of gait kinematics between professional ballet dancers and non-dancers.

Neuro Endocrinol Lett 2018 Dec 22;39(5):385-390. Epub 2018 Dec 22.

Faculty of Medicine, University of Ostrava, Ostrava,, Czech Republic.

Objectives: The aims of the study were to assess the kinematics of the lower limbs and pelvis during normal walking in professional ballet dancers and to investigate relationships between movements of segments of the lower limbs and pelvis.

Methods: Thirty one professional ballet dancers and twenty eight controls completed five walking trials at their preferred speed. Kinematic data in the basic anatomical planes for ankle, knee, and hip joints as well as for the pelvis were collected with an optoelectronic motion system. Read More

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December 2018
3 Reads

Accumulation of selected metals pollution in aquatic ecosystems in the Smeda river (Czech republic).

Neuro Endocrinol Lett 2018 Dec 22;39(5):380-384. Epub 2018 Dec 22.

University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Institute of Aquaculture and Protection of waters, Czech Republic.

Objectives: Biomonitoring of some slelected heavy metals in the Smeda river (Czech Republic) was carried out during 2015-2016 to assess the extent of environmental pollution. Attempts were also made to map the intensity of bioaccumulation in brown trout which was used as an indicator species. Monitoring of the environmental pollution of the Smeda river was carried in 2016. Read More

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December 2018
2 Reads

Sequencing of the insulin receptor (INSR) gene reveals association between gene variants in exon and intron 13 and schizoaffective disorder.

Neuro Endocrinol Lett 2018 Dec 22;39(5):371-379. Epub 2018 Dec 22.

Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

Objectives: From the hypothesis that an impaired insulin and insulin-like growth factor cellular signalling in brain and body might result in the development of schizophrenia or related psychoses, I in this study chose to thoroughly investigate the insulin receptor gene in patients with schizophrenia or schizoaffective disorder and controls.

Methods: For identification of single nucleotide polymorphisms (SNPs) of interest in the insulin receptor gene, targeted whole gene sequencing of DNA using the SOLiD technology was first carried out in two subgroups of the study population: 1) 49 schizophrenia or schizoaffective disorder patients with heredity for schizophrenia or related psychoses, and 2) 25 controls. Ten possible SNPs of interest were identified and these were then typed by standard methods in the whole study population consisting of 105 patients with schizophrenia or schizoaffective disorder and 60 controls. Read More

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December 2018
2 Reads

Mu Opioid Receptor Regulation of Gonadotropin-Releasing Hormone-Luteinizing Hormone Axis during Short-Term Food Deprivation: Role of Alpha1-Adrenoreceptor Signaling.

Neuro Endocrinol Lett 2018 Dec 22;39(5):363-370. Epub 2018 Dec 22.

School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA 71201, USA.

Objectives: Brain bio-energetic stability is required for optimal gonadal steroid positive-feedback activation of the gonadotropin-releasing hormone-I (GnRH-I)-pituitary luteinizing hormone (LH) neuroendocrine axis. Caudal hindbrain metabolic-sensory noradrenergic neurons counter energy deficiency by curtailing the mid-cycle LH surge. Central mu opioid receptors (mu-R) impose inhibitory effects of diverse physiological stimuli, including stress, on LH. Read More

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December 2018
5 Reads

Insulin resistance - "the good or the bad and ugly".

Neuro Endocrinol Lett 2018 Dec 22;39(5):355-362. Epub 2018 Dec 22.

Department of Endocrinology and Metabolic Diseases, Medical University of Lodz, Polish Mother's Memorial Hospital - Research Institute, Lodz, Poland.

Insulin resistance (IR) is a state of decreased sensitivity or responsiveness of target tissues to metabolic actions of circulating insulin. IR can be selective, involving only certain aspects of insulin action, i.e. Read More

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December 2018
2 Reads

Encephalitis with anti-NMDA receptor antibodies: paraneoplastic or non-paraneoplastic?

Neuro Endocrinol Lett 2018 Dec 22;39(5):351-354. Epub 2018 Dec 22.

Department of Neurology, Charles University in Prague, Faculty of Medicine in Hradec Kralove and University Hospital, Hradec Kralove, Czech Republic.

We report the case of an encephalitis patient with anti-N-methyl-D-aspartate receptor (NMDAR) antibody positivity. Anti-NMDAR encephalitis is a relatively rare autoimmune disease. In our patient, the diagnosis of anti-NMDAR encephalitis was established as late as several months after the first manifestations of the condition. Read More

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December 2018
2 Reads

Three diagnostic psychiatric subgroups in comparison to self-stigma, quality of life, disorder severity and coping management cross-sectional outpatient study.

Neuro Endocrinol Lett 2018 Oct;39(4):331-341

Department of Psychiatry, Faculty of Medicine and Dentistry, Palacky University Olomouc, and University Hospital Olomouc, Czech Republic.

Background: Much attention has been paid to psychological factors influencing characteristics, severity, and course of mental disorders. The objective of our investigation was to examine the interrelations among quality of life (QoL), self-stigma, and coping strategies, demographics and severity of the disorder in neurotic spectrum disorders, schizophrenia, and depressive spectrum disorders.

Methods: A total of 343 clinically stable Czech outpatients with different mental disorders (153 with neurotic spectrum disorders; 81 with depression, and 109 with schizophrenia spectrum disorders) were included. Read More

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October 2018
2 Reads

The effect of silver nanoparticles and silver ions on zebrafish embryos (Danio rerio).

Neuro Endocrinol Lett 2018 Oct;39(4):299-304

Department of Animal Protection, Welfare and Behaviour, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic.

Objectives: The aim of this study was to establish and evaluate the mortality rate, hatching rate and observe the presence of sublethal changes in zebrafish embryos after exposure to silver ions and nanoparticles.

Methods: Tests were conducted on newly fertilized zebrafish embryos, according to the modified OECD guideline 236, using a semistatic method and 96 hour incubation time. Silver nitrate and two different silver nanoparticles, stabilized with 0. Read More

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October 2018
2 Reads

The assessment of retina in pregnant women with myopia.

Neuro Endocrinol Lett 2018 Oct;39(4):321-324

Department of Ophthalmology, Military Institute of Medicine, Warsaw, Poland.

Objectives: Myopia is associated with increased frequency of retinal degenerative changes which are the risk factors of intra- and postpartal ophthalmological complications. Aim of this study was to analyze the degenerative lesions detected in opthalmological examination (including peripheral retinal lesions) as a potential risk factors for eyes' status in terms of delivery in myopic women.

Material And Methods: 254 pregnant women affected with myopia underwent opthalmological examination as a screening method to examine retina. Read More

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October 2018
1 Read

Regional differences in somatostatin receptor 2 (SSTR2) immunoreactivity is coupled to level of bowel invasion in small intestinal neuroendocrine tumors.

Neuro Endocrinol Lett 2018 Oct;39(4):305-309

Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.

Objective: Somatostatin receptor (SSTR) expression constitutes a pivotal cornerstone for accurate radiological detection and medical treatment of small intestinal neuroendocrine tumors (SI-NETs), and the development of somatostatin analogues for these purposes have revolutionized the clinical work-up. Previous assessments of SSTR isoform expression in SI-NETs have found correlations to overall prognosis and treatment response, however these analyses usually report overall tumoral immunoreactivity, and little is reported regarding histo-regional differences in expressional patterns.

Methods: Thirty-seven primary SI-NETs (WHO grade I, n=32 and WHO grade II, n=5) were collected and assessed for SSTR2 immunohistochemistry. Read More

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October 2018
1 Read
0.935 Impact Factor

Locomotion in young rats with induced brain cellular edema - effects of recombinant human erythropoietin.

Neuro Endocrinol Lett 2018 Oct;39(4):310-314

Institute of Physiology, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.

Objectives: Effect of recombinant human erythropoietin (rhEPO) on spontaneous motor activity was tested in young rats after intraperitoneal (i.p.) administration of rhEPO, followed by induction of cellular brain edema (CE). Read More

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October 2018
1 Read

Light-dark influence on enkephalinase activity in hypothalamus and pituitary.

Neuro Endocrinol Lett 2018 Oct;39(4):277-280

Unit of Physiology, University of Jaén, 23071 Jaén, Spain.

Objectives: Enkephalins functions are partly modulated by enkephalinases especially membrane-bound alanyl aminopeptidase (EC-3.4.11. Read More

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October 2018
4 Reads

Levels of selected contaminants in fish muscle from upper Nitra River.

Neuro Endocrinol Lett 2018 Oct;39(4):315-320

University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Institute of Aquaculture and Protection of waters, Ces, Czech Republic.

Objectives: This study determines the levels of selected contaminants in the muscle of three common fish species from the upper course of the Nitra River.

Design: Were detected levels of Zn, Cu, Ni, Cr, Pb, Cd and Hg in the muscle and correlations among selected metals as well as standard length and total weight in brown trout (Salmo trutta morpha fario), Alpine bullhead (Cottus poecilopus) and grayling (Thymallus thymallus).

Results: The content of analysed metals (mg. Read More

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October 2018
1 Read

Human mature milk zearalenone and deoxynivalenol levels in Turkey.

Neuro Endocrinol Lett 2018 Oct;39(4):325-330

Eskisehir Osmangazi University Faculty of Medicine, Department of Pediatric Neurology, Eskisehir, Turkey.

Introduction: Zearalenone (ZEA) and deoxynivalenol (DON) are toxic fungal secondary metabolites, found mainly in contaminated food, that are associated with serious health problems. It is important to identify undesirable toxins and metabolites that may be present in human milk. The aim of this study was to evaluate human milk ZEA and DON levels, total daily intake of ZEA and DON; and their possible relationship with maternal dietary habits. Read More

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October 2018
9 Reads

Gamma knife radiosurgery for local recurrence of glioblastoma.

Neuro Endocrinol Lett 2018 Oct;39(4):281-287

Department of Medical Physics, Na Homolce Hospital, Prague, Czech Republic.

Objective: Local recurrence of glioblastoma is observed in most patients after standard oncologic treatment (surgery, chemotherapy and radiotherapy). Stereotactic radiosurgery with the Leksell Gamma Knife (SRS with LGK) was used to treat recurrent tumors in selected cases, and retrospective analysis of treatment outcome was performed.

Methods: Altogether 126 patients were treated for glioblastoma at our center from 1992-2014. Read More

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October 2018
4 Reads

Endocrine response to high intensity barbell squats performed with constant movement tempo and variable training volume.

Neuro Endocrinol Lett 2018 Oct;39(4):342-348

Charles University in Prague, Faculty of Physical Education and Sport, Department of Sport Games, Prague, Czech Republic.

Objective: Research indicates that among the many elements of resistance exercise protocols, training volume and total training load are the key factors for post-exercise increase in the secretion of testosterone (T), growth hormone (GH), insulin-like growth factor (IGF-1) and cortisol (C). The aim of this study was to determine the effects of resistance exercises with variable volume and constant intensity and movement tempo on post-exercise concentrations of selected anabolic and catabolic hormones.

Materials And Methods: 28 experienced powerlifters (27. Read More

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October 2018
1 Read

Depressive symptoms are associated with higher morning plasma cortisol in primary care subjects.

Neuro Endocrinol Lett 2018 Oct;39(4):288-293

Endocrinology Department, School of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile.

Background: Cortisol dysregulation has a potential role in depression.

Aim And Methods: We evaluated depressive symptoms using the Hamilton Rating Scale for Depression in 48 primary care subjects without history of previous or current depression and its association with cortisol dysregulation (morning plasma cortisol, 24-hour urinary free cortisol and cortisol metabolites). Presence of metabolic syndrome and inflammatory parameters were also assessed. Read More

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October 2018
1 Read

Bisphenol A as an environmental pollutant with dual genotoxic and DNA-protective effects.

Neuro Endocrinol Lett 2018 Oct;39(4):294-298

Department of Genetics, Faculty of Natural Sciences, Comenius University, Bratislava, Slovakia.

Objectives: Bisphenol A (BPA) is an endocrine disruptor which has been shown to be a harmful compound for living organisms. It is the main component of the most commonly used plastic products such as plastic bottles, food cans and containers or dental fillings, and other medical aids. Recently, it has become a new environmental pollutant. Read More

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October 2018
2 Reads

The over-expression of GH/GHR in tumour tissues with respect to healthy ones confirms its oncogenic role and the consequent oncosuppressor role of its physiological inhibitor, somatostatin: a review of the literature.

Neuro Endocrinol Lett 2018 Sep;39(3):179-188

Di Bella Foundation, Via Guglielmo Marconi 51 Bologna, 40122, Italy.

The interaction between pituitary hormones, GH - PRL, and Growth Factors, GF, plays a fundamental role in the physiological and neoplastic mechanisms of growth, the latter using these factors to a much greater extent compared to the former, with a direct dose-dependent effect on the speed of local or metastatic expansion. In hormone-dependent tumours, the respective male and female sex hormones interact with GH - PRL - GF to sustain the expansion of the tumour. We carried out a review of the literature on the relationship between the expression of GH and GHR in tumour tissues compared to healthy tissues, and on the correlation between this expression and tumour aggressiveness. Read More

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September 2018
2 Reads

Revisiting respiratory muscle strength and pulmonary function in spinal cord injury: The effect of body positions.

Neuro Endocrinol Lett 2018 Sep;39(3):189-195

Department of Rehabilitation Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Republic of Korea.

Objectives: In the subjects with high cervical spinal cord injury (SCI), The difference of respiratory muscle strength and pulmonary function according to supine and sitting position were investigated whether there are changes in the tendency.

Methods: Twenty-three subjects with high cervical SCI and 23 subjects with low cervical and thoracic SCI were evaluated. The reference neurological level of injury for dividing the groups was fifth cervical vertebrae (C5). Read More

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September 2018
12 Reads

Personality disorder in marriage and partnership - a narrative review.

Neuro Endocrinol Lett 2018 Sep;39(3):159-171

Department of Psychiatry, Faculty of Medicine and Dentistry, University Palacky Olomouc, University Hospital, 77520 Olomouc, Czech Republic.

Background: Partner conflicts are the most common precipitating factors of decompensation of psychiatric disorders, including personality disorders. Personal characteristics play a fundamental role in both the prediction of marital satisfaction of the individual as well as the satisfaction of the couple as a whole.

Method: Narrative Review of the articles, books and book chapters within the period 1956 - 2016 using PubMed, Web of Science, and Scopus databases with keywords "personality disorder," "partnership," marital problems," "marital conflicts. Read More

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September 2018
10 Reads

Neuroendocrine aspects of anorexia nervosa and bulimia nervosa.

Neuro Endocrinol Lett 2018 Sep;39(3):172-178

Department of Neurology, Medical University of Warsaw, Bielanski Hospital, Warsaw,, Poland.

Endocrine dysfunctions in eating disorders (anorexia nervosa, bulimia nervosa) result from disturbed regulation of hypothalamo-pituitary-gonadal, hypothalamo-pituitary-adrenal, hypothalamo-pituitary-thyroid and hypothalamo-pituitary-GH-IGF1 axes as well as of altered peripheral endocrine metabolism. Some peptides of hypothalamic origin, as well as those secreted by the adipose tissue and gastrointestinal tract including pancreatic hormones, are involved in the control of appetite and satiety. These peptides play also an important role in the mechanism of hormonal secretion. Read More

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September 2018
18 Reads

Hypophysitis and other autoimmune complications related to immune checkpoints inhibitors´ treatment: Spectrum of imaging appearances.

Neuro Endocrinol Lett 2018 Sep;39(3):196-204

Radiology Department, Third Faculty of Medicine, Charles University, Faculty Hospital Kralovske Vinohrady, Prague, Czech Republic.

Objectives: Immune checkpoints inhibitors (ICI) represent a new therapy option for the treatment of several advanced tumors. However, this therapy has been linked to a spectrum of ICI related autoimmune (AI) adverse events. Some may be life threatening and their diagnosis is tricky. Read More

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September 2018
2 Reads

Coexistence of neurofibromatosis type 1 with multiple malignant neoplasia.

Neuro Endocrinol Lett 2018 Sep;39(3):149-155

Clinical Department of Endocrinology, Jagiellonian University in Krakow, Poland.

Neurofibromatosis type 1 (NF1, von Recklinghausen disease) is inherited in autosomal dominant way genetic disorder, with an incidence at birth 1:3000. It is one of the most common congenital disorders. It is characterized by café-au-lait spots, neurofibromas, and less common MPTST and gliomas of the optic nerve. Read More

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September 2018
12 Reads

Clinical effectiveness of parenteral trazodone for the management of psychomotor activation in patients with bipolar disorder.

Neuro Endocrinol Lett 2018 Sep;39(3):205-208

Department of Molecular Medicine and Clinical Department of Mental Health, University of Siena, Siena, Italy.

Objectives: Trazodone is a multifunctional triazolopyridine drug with antidepressant, anxiolytic, sedative, and hypnotic properties. The current retrospective study was designed to investigate the effectiveness of trazodone for reducing acute psychomotor activation (PA) in patients with bipolar disorder (BD). We specifically reasoned that a parenteral route of administration could offer potential advantages in this clinical setting. Read More

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September 2018
16 Reads

Cellular brain edema induced by water intoxication in rat experimental model.

Neuro Endocrinol Lett 2018 Sep;39(3):209-218

Institute of Physiology, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.

Objectives: This paper presents our own rat model of the cellular brain edema, induced by water intoxication (WI). The basic principle of the model is an osmotic imbalance in the cell membrane followed by an intracellular flow of sodium and simultaneous accumulation of water leading to the subsequent increase of BBB permeability.

Methods: The usefulness of the model was tested in precisely specified conditions whose results were clearly expressed. Read More

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September 2018
10 Reads

A rare case of ectopic pregnancy - retroperitoneal ectopic pregnancy.

Neuro Endocrinol Lett 2018 Sep;39(3):156-159

Department of Pathology, Hospital Ceske Budejovice , Czech Republic.

Ectopic pregnancy is a condition when fertilized egg implants outside the uterine cavity. The reported incidence is about 0.5-1% of all pregnancies. Read More

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September 2018
2 Reads

25(OH)D serum concentration in women with menstrual disorders -risk factors for Vitamin D deficiency.

Neuro Endocrinol Lett 2018 Sep;39(3):219-225

1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Warsaw, Poland, Pl. Starynkiewicza 1-3, 02-015 Warsaw, Poland.

Introduction: Vitamin D (VD) plays a crucial role in calcium metabolism as well as immunological and endocrine homeostasis. Previous studies revealed strong inverse correlation between VD levels and insulin resistance, parathyroid dysfunctions and autoimmune thyroid disease. Insufficient evidence concerns its dependency of ovarian hormones. Read More

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September 2018
9 Reads

Effects of alprostadil combined with calcium dobesilate in patients with diabetic peripheral neuropathy.

Neuro Endocrinol Lett 2018 05;39(2):143-147

Department of Endocrinology, Chengyang People's Hospital in Qingdao, Qingdao 266109, China.

Objective: To observe the clinical curative effects of alprostadil combined with calcium dobesilate in type 2 diabetes patients with peripheral neuropathy.

Methods: We randomly divided 120 type 2 diabetes patients with diabetic peripheral neuropathy into two groups. The treatment group was prescribed alprostadil (10 μg, once daily) and oral calcium dobesilate (0. Read More

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May 2018
9 Reads

Autonomic dysfunction in patients with irritable bowel syndrome evidenced by alterations of salivary alpha-amylase secretion.

Neuro Endocrinol Lett 2018 05;39(2):125-129

The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang, Jiangxi, China.

Background: Patients with irritable bowel syndrome (IBS) frequently present with alterations of autonomic activity, especially higher sympathetic activity. Salivary alpha-amylase (sAA) has been implicated as a non-invasive biomarker to reflect the sympathetic activity. Thus, the current study aimed to determine if alterations of sAA secretion could be addressed in IBS patients. Read More

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May 2018
4 Reads

Integrated analysis of differentially expressed lncRNAs in Medial Temporal Lobe Epilepsy.

Neuro Endocrinol Lett 2018 05;39(2):119-124

Department of Neurology, Zhejiang Hospital, Hangzhou, 310000, Zhejiang, China.

Background: Medial temporal lobe epilepsy (MTLE) is the most frequent type of epilepsy. In recent years, the important roles of lncRNAs in regulating human diseases progression had been implicated, including in epilepsy. However, comprehensive analysis of differentially expressed lncRNAs in Medial Temporal Lobe Epilepsy was still lacking. Read More

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May 2018
2 Reads
0.940 Impact Factor

Expression of MT1 receptor in patients with gastric adenocarcinoma and its relationship with clinicopathological features.

Neuro Endocrinol Lett 2018 05;39(2):111-118

Pharmaceutical Sciences Research Centre, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Gastric cancer accounts 8% of the total cancer cases leading to 10% of total cancer deaths worldwide. The indoleamine N-acetyl-5-methoxytryptamine, better known as melatonin, is the principal hormone produced by the pineal gland. Recently, it has been well documented some anti-cancer roles of melatonin in some malignancies as breast and colon cancer; as well as some its protective roles in the GI tract that have been known as free radical scavenger, antimitogenic and apoptotic properties. Read More

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May 2018
27 Reads
0.940 Impact Factor

Rapidly progressive non-alcoholic fatty liver disease due to hypopituitarism. Report of 5 cases.

Neuro Endocrinol Lett 2018 05;39(2):99-104

Department of Endocrinology, 302 Military Hospital of China, Beijing, China.

Background: A few reports had revealed the clinical associations between hypopituitarism and non-alcoholic fatty liver disease (NAFLD). Further evidences were needed.

Objectives: To report 5 cases of young patients with rapidly progressive NAFLD in conjunction with hypopituitarism, aiming to detect the associations. Read More

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May 2018
4 Reads

The Comorbidity of Focal Epilepsy and Narcolepsy Type 1 - Two Case Reports.

Neuro Endocrinol Lett 2018 05;39(2):95-98

1st Department of Neurology, Faculty of Medicine, Comenius University, Bratislava, Slovakia.

The aim of this study is to remind the possibility of co-occurrence of epilepsy and narcolepsy. In the first case report, narcolepsy type 1 was diagnosed in 29-year-old female. After one year of the treatment with modafinil a new episodes of automatic behavior appeared. Read More

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May 2018
5 Reads

Diagnosis and treatment of solitary fibrous tumor/hemangiopericytoma of central nervous system. Retrospective report of 17 patients and literature review.

Neuro Endocrinol Lett 2018 05;39(2):88-94

Department of Neurosurgery, China-Japan Union Hospital, JiLin University, China.

To investigate the diagnosis, treatment and prognosis of solitary fibrous tumor (SFT)/ hemangiopericytoma (HPC) of central nervous system (CNS), we retrospectively reviewed records of 17 patients who were treated for CNS SFT/HPC at the Department of Neurosurgery, China-Japan Union Hospital of Jilin University from December 2010 to June 2016, and reevaluated their pathological diagnoses according to the 2016 WHO classification of CNS tumors. We then analyzed their clinical symptoms, imaging characteristics, treatments and outcomes. Clinical manifestations of CNS SFT/HPC were diverse, but mainly included headache, increased intracranial pressure, seizures, and focal neurological deficits. Read More

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May 2018
3 Reads

Limbic encephalitis associated with antibodies against the α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic acid receptor: a case report.

Neuro Endocrinol Lett 2018 05;39(2):85-87

Department of Neurology, The First Hospital, Jilin University, Changchun, China.

We report a case of a 51-year-old man with limbic encephalitis (LE) associated with antibodies against the α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic acid receptor (AMPAR). The patient presented with anterograde memory loss for 2 months. Cranial magnetic resonance and electroencephalogram were normal. Read More

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May 2018
3 Reads

Discrepancy between readiness to change, insight and motivation in alcohol-dependent inpatients.

Neuro Endocrinol Lett 2018 05;39(2):135-142

Department of Psychology Sciences, Faculty of Social Science and Health Care, Constantine the Philosopher University in Nitra, Slovakia.

Background: Poland, Czech Republic, and the Slovak Republic are countries with high alcohol consumption, and alcohol-induced disorders are in the ten leading causes of Years Lost due to Disability. Therefore it is necessary to study factors as insight, motivation, and readiness to change for the better understanding the variables which are in probably connected with therapeutic effectiveness.

Aim: The purpose of the study was to examine the state of readiness to change at the beginning and the end of inpatient short (six weeks) and long (12 weeks) therapeutic program in the Slovak Republic, Poland, and the Czech Republic, and look for the relationship between readiness to change, insight, and motivation in alcohol-dependent persons. Read More

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May 2018
3 Reads

Amygdala and emotionality in Parkinson's disease: An integrative review of the neuropsychological evidence.

Neuro Endocrinol Lett 2018 05;39(2):105-110

Prague College of Psychosocial Studies, Prague, Czech Republic.

Parkinson's disease (PD) is often accompanied by significant changes in emotionality, such as apathy, anhedonia, anxiety and depression. The present review summarizes the empirical evidence, including amygdala changes and psychological changes in emotionality in people suffering from PD. Seventeen empirical full-text articles including research on both amygdala and emotionality in PD were reviewed. Read More

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May 2018
4 Reads

Estimation of testosterone/cortisol ratio by resting state eeg delta/beta ratio in elderly people.

Neuro Endocrinol Lett 2018 Mar;39(1):75-82

Department of Biomedical Engineering, Faculty of Engineering, Mahidol University, Thailand.

Objectives: Testosterone and cortisol are the end products of the hypothalamus-pituitary-gonadal and hypothalamus-pituitary-adrenal axes. Both hormones affect brain anatomy and brain activity, which is positively correlated with the testosterone/cortisol ratio. The aim of the present study was to observe the main effect and interaction between testosterone and cortisol in relation to brain activity and whether it is possible to predict neuroendocrine levels. Read More

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March 2018
5 Reads

Shall we diagnose metabolic syndrome in adolescents?

Neuro Endocrinol Lett 2018 05;39(2):130-134

Department of Pediatric and Adolescent Endocrinology, Chair of Pediatrics, Jagiellonian University, Medical College, Wielicka St. 265 30-663 Krakow, Poland.

Background: The clinical value of the diagnosis of metabolic syndrome (MS) in children and adolescents remains unclear. The aim of the present study was to assess the occurrence of metabolic complications, other than included in 2007 IDF MS definition, in obese children and adolescents METHODS: The study included 75 (33 boys) obese adolescents (mean age 13.9 years, mean BMI SDS 4. Read More

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May 2018
3 Reads

Antipsychotics in Hyperthyroid-Related Psychosis: Case Report and Systematic Review.

Neuro Endocrinol Lett 2018 Mar;39(1):65-74

Department of Psychiatry, NYU School of Medicine, 550 1st Avenue, New York, NY, 10016, USA.

Objectives: Hyperthyroidism has been associated with relatively rare presentations of psychotic symptoms. We report an example of the successful use of antipsychotics to manage psychotic symptoms in hyperthyroid-related psychosis. Furthermore, we systematically describe the available literature on the use of antipsychotics in this setting to determine the associated relative efficacies of the various antipsychotic agents. Read More

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March 2018
3 Reads

Content of fatty acids in a diet and the homocysteine levels in women with fertility disorders.

Neuro Endocrinol Lett 2018 Mar;39(1):56-64

Department of Clinical Dietetics, Medical University of Warsaw, Ciołka St. 27, 01-445 Warsaw, Poland.

Objectives: Assessment of the effects of consumption of fatty acids on the homocysteine levels in women with fertility disorders.

Methods And Results: The study included 286 women at the age between 23 and 46 years (the mean 33.13±4. Read More

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March 2018
5 Reads

Telomere length and TERT abnormalities in pituitary adenomas.

Neuro Endocrinol Lett 2018 Mar;39(1):49-55

Department of Molecular and Translational Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland.

Objectives: Pituitary adenomas (PAs) are among the most frequent intracranial tumors in humans. Abnormal telomerase activity and telomere lengthening are features of tumor cells. They may result from mutations in TERT promoter region, gene amplification or aberrant DNA methylation pattern. Read More

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March 2018
6 Reads

Lymphocytic hypophysitis associated with Behcet's disease: A case report and review of the literature.

Neuro Endocrinol Lett 2018 Mar;39(1):43-48

Department of Endocrinology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Lymphocytic hypophysitis (LH) is a rare inflammatory disorder involving the pituitary gland, often with other autoimmune diseases combined. The coexistence of LH and Behçet\'s disease (BD) is a rare combination and only one case was reported in the previous literatures. A 50-year-old man was admitted into Sir Run Run Shaw Hospital presented with frontal headache and fatigue which had lasted for four months. Read More

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March 2018
12 Reads

Signs of impaired blood-brain barrier function and lower IgG synthesis within the central nervous system in patients with schizophrenia or related psychosis, compared to that in controls.

Neuro Endocrinol Lett 2018 Mar;39(1):33-42

Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

Objectives: Evidence has accumulated that an inflammatory, possibly autoimmune-mediated, process in the central nervous system (CNS), and by way of an aberrant immune system, may underlie the development of schizophrenia. Therefore, the aim of this study was to evaluate patients with schizophrenia or related psychosis for blood-brain barrier (BBB) function and immunoglobulin (Ig)G synthesis within the CNS.

Methods: Fifteen patients with schizophrenia or schizoaffective disorder and 12 controls were investigated using lumbar puncture and blood sampling. Read More

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March 2018
3 Reads

Physiological responses to different neuromuscular movement task during eccentric bench press.

Neuro Endocrinol Lett 2018 Mar;39(1):26-32

Charles University in Prague, Faculty of Physical Education and Sport, Department of Sport Games, Prague, Czech Republic.

Objectives: Increasing muscular hypertrophy is one of the main reasons for participating in a resistance training program, where different movement task such as eccentric cadences may serve as a potent hypertrophic stimulus and improve movement stability. Aim of this study was to investigate the physiological responses between slow 6/0/2/0 (SLOW) and moderate 2/0/2/0 (REG) eccentric cadences during five sets of bench press to failure using 70% 1 repetition maximum (1RM).

Materials And Methods: Blood samples from sixteen men (21-29y, 85. Read More

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March 2018
4 Reads