2,645 results match your criteria Neuro endocrinology letters[Journal]


Angiotensinogen gene T174M polymorphism is related to Hashimoto's thyroiditis.

Neuro Endocrinol Lett 2019 Mar;39(8):579-585

Department of Endocrinology and Metabolic Disease, Medical University of Lodz, Poland.

Objectives: The Hashimoto thyroiditis is found to be Th1-related autoimmunity. Recently, it has been proved that the renin-angiotensin-aldosterone system (RAAS) may be involved in promoting Th1-mediated autoimmune diseases. However, the role of RAAS in HT pathogenesis remains still unknown. Read More

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March 2019
1 Read

The association of serum lipid level with ischemic stroke in the elderly of Xinjiang.

Neuro Endocrinol Lett 2019 Mar;39(8):572-578

Department of Neurology, Friendship Hospital to Urumqi, 830049, China.

Background: The aim of the present study is to determine the association of serum lipid level in the above 55-year-old age elderly with ischemic stroke (IS) in Xinjiang regions, China.

Methods: 408 patients with IS and 347 healthy individuals as control in the ≥55-year-old elderly were selected for the present study in Xinjiang province of China from July 2010 to July 2012. Patients were divided into different groups according to the IS subtypes (large-artery atherosclerosis, LAA; cardio-aortic embolism CE; small-artery occlusion, SAO), plague stability, hypertension and diabetes. Read More

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March 2019
1 Read

Tissue metallothionein response in the Japanese quail associated with exposure to cyanobacterial biomass, lead and the Newcastle disease virus.

Neuro Endocrinol Lett 2019 Mar;39(8):567-571

Department of Ecology and Diseases of Game, Fish and Bees, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic.

Objectives: Here we tested the hypothesis that multiple toxic and infectious stressors combine in their adverse effects to produce higher tissue responses of metallothioneins (MTs) in birds.

Methods: We used Japanese quails as a model avian species. The study is based on data obtained from single and combined exposures of Japanese quails to cyanobacterial biomass containing microcystins, lead and a live Newcastle disease vaccination virus. Read More

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March 2019
1 Read

Thioredoxin is a potential therapy for light-induced photoreceptor degeneration in diabetic mice.

Neuro Endocrinol Lett 2019 Mar;39(8):561-566

The Second Affiliated Hospital, School of Medicine, Xi'an Jiaotong University, Xi'an 710004, China.

Background: Retina degeneration is a set of disease that can be characterized by progressive loss of rod or cone photoreceptors that can experience higher light exposure compared with other parts of our body.

Material And Methods: To investigate in diabetic mice the effects of different light on retinal photoreceptor and its related mechanisms, 4-6 weeks male Balb/c mices were randomly divided into control group, light treatment group (light 1 and light 2), light treatment with filter membrane group (LFM1 and LFM2), light treatment filter blue light group (LFB), diabetic group (DM), diabetic with light treatment group (DM+Light), diabetic light treatment with filter membrane group (DM+LFM1 and DM+LFM2), diabetic light treatment with filter blue light group (DM+LFB). Electroretinography (ERG) was used to assess retinal function. Read More

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The influence of electromagnetic fields generated by wireless connectivity systems on the occurrence of emotional disorders in women: A preliminary report.

Neuro Endocrinol Lett 2019 Mar;39(8):550-560

Department of Woman's Health. Institute of Rural Health, Lublin, Poland.

Objectives: The aim of the study was to assess the influence of electromagnetic fields (EMFs) generated by wireless connectivity systems on the occurrence of emotional disorders in women working in the health service and in trade. We also analyzed the relationship between physical activity and emotional state.

Methods And Results: The study was conducted on a sample of 200 women aged 25 to 35, in Lublin, Poland, in 2017. Read More

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March 2019
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Etiology, Risk Factors and Outcome of 1003 Cases of Infective Endocarditis from a 33-year National Survey in the Slovak Republic: An increasing proportion of elderly patients.

Neuro Endocrinol Lett 2019 Mar;39(8):544-549

North London Postgraduate Medical School, London, UK.

Background: Infective endocarditis (IE) is still a significant cause of mortality in European hospitals, despite of the fact, that large nationwide studies were performed in last twenty years and pathogens are well known. The aim of the study was to assess risk factors, mortality, etiology and proportion of elderly patients within a longitudinal nation wide survey of infectious endocarditis in Slovakia.

Patients And Methods: Etiology, risk factors and outcome of 1003 cases of infective endocarditis (IE) in Slovakia over the last 33 years have been assessed. Read More

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March 2019
2 Reads

Therapy for Gastroenteropancreatic Neuroendocrine Tumors: drug evaluation reports review in Spain.

Neuro Endocrinol Lett 2019 Mar;39(8):537-543

BCN Health Economics and Outcomes Research S.L., Barcelona, Spain.

Objectives: In Spain it is necessary to conduct additional studies to determine place in therapy and cost-effectiveness of a drug. The main objective of this study is to identify all drug assessments and health technology assessment reports of the drugs for gastroenteropancreatic (GEP) neuroendocrine tumors (NET) at a national, regional and hospital level and to summarize the efficacy in terms of outcome measures, adverse events, economic impact and final recommendations.

Methods: A search was made on the GENESIS website for drug evaluation reports regarding GEP NET, including gastrointestinal and bronchopulmonary, to identify the drug assessments at a regional and hospital level. Read More

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Fructose-1,6-bisphosphatase deficiency presented with complex febrile convulsion.

Neuro Endocrinol Lett 2019 Mar;39(8):533-536

Division of Clinical Genetics, Department of Pediatrics, Severance Children's Hospital, Yonsei University College of Medicine, Republic of Korea.

Fructose-1,6-bisphosphatase (FBPase) deficiency is a rare inborn error of metabolism affecting gluconeogenesis caused by FBP1 gene mutations. It could be more fatal to infants and children when glycogen reserves are insufficient. A 4-year-old girl was admitted with complex febrile convulsion. Read More

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March 2019
2 Reads

Effects of peripheral administration of GH and IGF-I on gene expression in the hippocampus of hypophysectomised rats.

Neuro Endocrinol Lett 2019 Feb;39(7):525-531

Department of Internal Medicine, Institute of Medicine, The Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.

Objective: Growth hormone (GH) increases insulin-like growth factor I (IGF-I) production and both hormones affect hippocampal plasticity. We have previously shown that Hbb and Alas2 in the rat hippocampus were robustly regulated by GH-infusions for six days, whereas other transcripts were weakly affected. Here, we explored the effects of prolonged GH administration on transcripts linked to neuroprotection and investigated whether serum IGF-I administration may exert similar effects. Read More

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February 2019
4 Reads

Tyrosine kinase inhibitors vandetanib, lenvatinib and cabozantinib modulate oxidation of an anticancer agent ellipticine catalyzed by cytochromes P450 in vitro.

Neuro Endocrinol Lett 2019 Feb;39(7):515-524

Department of Biochemistry, Faculty of Science, Charles University, Albertov 2030, 128 40 Prague 2, Czech Republic.

Objectives: Vandetanib¸ lenvatinib, and cabozantinib are tyrosine kinase inhibitors (TKIs) targeting VEGFR subtypes 1 and 2, EGFR and the RET-tyrosine kinase, thus considered as multiple TKIs. These TKIs have already been approved for treating patients suffering from thyroid cancer and renal cell carcinoma. Ellipticine, a DNA-damaging drug, is another anticancer agent that is effective against certain tumors of the thyroid gland, ovarian carcinoma, breast cancer and osteolytic breast cancer metastasis. Read More

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February 2019
1 Read

Potential of the multivitamin-mineral-trace element composition LaVita® before, during and after pregnancy.

Neuro Endocrinol Lett 2019 Feb;39(7):501-514

International Society for Applied Preventive Medicine (I-GAP); and Health Campus, St. Elisabeth University of Health and Social Sciences (EU), Bratislava, Slovakia.

Objectives: Pregnancy is a period in life with a high demand of micronutrients. A prophylactic supplementation of folic acid to reduce the risk of neurological malformations in the newborn is common practice. The array of essential micronutrients during pregnancy includes neurotropic vitamins (Vitamin B6, B12 and folic acid), minerals like iron, and trace elements like zinc. Read More

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February 2019
2 Reads

Tapentadol in an Experimental Animal Model of Acute Orofacial Pain.

Neuro Endocrinol Lett 2019 Feb;39(7):496-500

Department of Normal, Pathological and Clinical Physiology, Third Faculty of Medicine, Charles University, Prague, Czech Republic.

Objective: Tapentadol exhibits a synergistic dual effect effect (MOR / NRI) -agonist effect on noradrena-line reuptake inhibition (NRI). Tapentadol is effective on pain with neuropathic characteristics, therefore we decided to use it in an experimental model of acute orofacial pain.

Methods: The Orofacial Stimulation Test, developed by Ugo Basile, measures hypersensitivity to thermal or mechanical stimulation of the trigeminal area. Read More

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February 2019
1 Read

Clinical characteristics of subacute thyroiditis is different than it used to be - current state based on 15 years own material.

Neuro Endocrinol Lett 2019 Feb;39(7):489-495

Department of Endocrinology and Metabolic Diseases, Polish Mother's Memorial Hospital - Research Institute, Lodz, Poland.

Introduction: The clinical characteristics of subacute thyroiditis (SAT) has been changing in recent years. There are more and more patients with painless SAT, and more cases of SAT with elevated levels of anti-thyroid antibodies were reported. The aim of the study was to evaluate the clinical characteristics of SAT patients with special regard to the differences between the previously described and currently observed features of the disease. Read More

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February 2019
1 Read

Selected Risk Factors of Falls in Hospitalized Patients: A Case-Control Study.

Neuro Endocrinol Lett 2019 Feb;39(7):481-488

Pharmaceutic Faculty, Hradec Králové, Charles University, Department of Social and Clinical Pharmacy, Czech Republic.

Theory: Patients falls have a multifactorial character and typically have multiple causalities.

Goal: The goal of the study was to identify risk factors for falls of hospitalized patients.

Methodology: This was a case-control study. Read More

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February 2019

Diagnosis of cerebral venous thrombosis: a single centre experience.

Neuro Endocrinol Lett 2019 Jan;39(6):473-479

Department of Neurology, Third Faculty of Medicine, Charles University and Faculty Hospital Kralovske Vinohrady, Prague, Czech Republic.

Objectives: Cerebral venous thrombosis is a serious cerebrovascular disease. Due to the variability of clinical symptoms and the scarcity of occurrence, this diagnosis is often delayed. The aim of the study was to describe the risk factors, the initial findings and the imaging methods that lead to the diagnosis. Read More

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January 2019
1 Read

Evaluation of platinum nanoparticles ecotoxicity using representatives of distinct trophic levels of aquatic biocenosis.

Neuro Endocrinol Lett 2019 Jan;39(6):465-472

Department of Ecology and Diseases of Game, Fish and Bees, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Czech Republic.

Objectives: The aim of this study was to clarify the influence of three different sizes of platinum nanoparticles on aquatic ecosystem and assess the toxic effect in term of particle size. Tests were conducted on organisms representing all trophic levels of the aquatic ecosystem, namely producers (duckweed Lemna minor), consumers (water fleas Daphnia magna) and decomposers (bacteria Vibrio fischeri).

Design: Experiments were carried out methodologically in accordance with the following standards: OECD 221 guideline (Lemna sp. Read More

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January 2019
3 Reads

Efficacy of endovascular intervention in patients with unruptured posterior communicating artery aneurysm-related oculomotor nerve palsy.

Neuro Endocrinol Lett 2019 Jan;39(6):459-464

Department of Interventional Neuroradiology, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Objectives: Oculomotor nerve palsy (ONP) is commonly encountered in daily neurosurgical activities. The ONP secondary to un-ruptured PComA aneurysm might be a unique entity that was different in diagnosis, treatment and prognosis from its ruptured counterparts. Perhaps as a result of the limitation in sample size, studies that solely focused on factors affecting recovery of ONP in patients with unruptured corresponding PComA aneurysms were scarce. Read More

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January 2019
1 Read

Composition of tissue fatty acids of phospholipids depends on tumor localization and disease progression in colorectal patients.

Neuro Endocrinol Lett 2019 Jan;39(6):454-458

Clinical Biochemistry Department, IP, Jagiellonian University College of Medicine, Krakow, Poland.

Objectives: Fatty acids play a role in development and progression of colon cancer. The aim of this study was to assess the relation between tissue fatty acids (saturated fatty acids, unsaturated fatty acids, the ratio of C18 to C18:1 - index of fatty acids saturation, SI), colorectal tumor localization and disease progression.

Methods And Results: Total of 49 patients (14 with proximal colon, 13 with distal colon and 22 with rectal tumor localization) were studied. Read More

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January 2019

Toxicity of wastewater from health care facilities assessed by different bioassays.

Neuro Endocrinol Lett 2019 Jan;39(6):441-453

Faculty of Medicine and Dentistry, Palacký University, Hněvotínská 3, Olomouc, 775 15, Czech Republic.

Objectives: The purpose of this study was to determine toxicity of wastewater from hospitals in the Czech Republic using traditional and alternative toxicological methods. The pilot study comprised weekly dynamics of sewage ecotoxicity of treated wastewater from one hospital in two different seasons. A detailed investigation of wastewater ecotoxicity, genotoxicity and reprotoxicity followed in five different hospitals. Read More

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January 2019
4 Reads

Metabolic characteristics of women diagnosed with polycystic ovary syndrome (PCOS) according to the Rotterdam criteria - our own experience.

Neuro Endocrinol Lett 2019 Jan;39(6):434-440

Department of Endocrinology and Metabolic Diseases, Polish Mother's Memorial Hospital - Research Institute, Lodz, Poland.

Objectives: Analysis of metabolic features of women diagnosed with the PCOS among female patients of Department of Endocrinology and Metabolic Diseases, the Polish Mother's Memorial Hospital - Research Institute (DEMD, PMMH-RI). The secondary aim was assessment if diagnosis of PCOS (according to the Rotterdam criteria) may imply any standard treatment.

Material And Methods: The study was retrospective analysis of patients hospitalized in DEMD. Read More

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January 2019
2 Reads

Metabolic and neurobehavioral response following intraovarian administration of autologous activated platelet rich plasma: First qualitative data.

Neuro Endocrinol Lett 2019 Jan;39(6):427-433

Center for Reproductive Medicine and Infertility, Weill Medical College of Cornell University; New York NY, USA.

Objectives: This work assessed sexual and neurobehavioral parameters after ovarian treatment with autologous PRP.

Design: Questionnaire study.

Material And Methods: Patients receiving ovarian PRP injection (n=80) due to low ovarian reserve and/or at least 1 prior failed IVF cycle were sampled. Read More

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January 2019
0.935 Impact Factor

Uterine torsion in the second trimester of pregnancy.

Neuro Endocrinol Lett 2019 Jan;39(6):423-426

1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Pl. Starynkiewicza 1-3, 02-015 Warsaw, Poland.

Objectives: Torsion of the pregnant uterus is a very rare complication. It may occur at any gestational age. The treatment depends on the intensity of symptoms, intraoperative ischemic signs and the gestational age. Read More

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January 2019
1 Read

Evaluation of the effectiveness of treatment of vulvar lichen sclerosus et atrophicus. Analysis of own material and review of the literature.

Neuro Endocrinol Lett 2018 Dec;39(5):417-421

1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Pl. Starynkiewicza 1-3, 02-015 Warsaw, Poland.

Material And Methods: The study group included eleven female patients aged 18-77 years with a diagnosis of lichen sclerosus. Basic therapy consisted in the application of clobetasol in the first month and then once a day for the following two months. Then, clobetasol was recommended once a week until full resolution of the symptoms. Read More

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December 2018
17 Reads

Selected bisphenols and phthalates screened for estrogen and androgen disruption by in silico and in vitro methods.

Neuro Endocrinol Lett 2018 Dec;39(5):409-416

Charles University in Prague, Third Faculty of Medicine, Ruská 87, Prague, Czech Republic.

Objectives: The aim of this study was to detect endocrine disruption potential of selected bisphenols and phthalates, compare in silico prediction with results from two in vitro methods and bring up-to-date information on development of EU legislation, available in vitro methods and biomechanisms involved in endocrine disruption.

Material And Methods: In silico approach based on the OECD QSAR Toolbox was used for prediction of estrogen receptor α binding. OECD TG 455 assay and a yeast-based YES/YAS assay was used to determine the interactions with human estrogen (ERα) and androgen receptors. Read More

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December 2018
9 Reads

Assessing the awareness of Czechs, age 40+, on the link between lifestyle choices and risk factors for cardiovascular diseases.

Neuro Endocrinol Lett 2018 Dec;39(5):401-408

Institute for Clinical and Experimental Medicine, Department of Preventive Cardiology, Prague, Czech Republic.

Objectives: Cardiovascular diseases constitute the main cause of disability and premature death worldwide. Those diseases will continue to endanger health unless the public understands clearly and completely which risk factors contribute to the development of these diseases and what they can do to avoid these risks. This article assesses the understanding of risk factors that can lead to the development of heart and vessel diseases. Read More

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December 2018
3 Reads

Mathematical evaluation of melatonin secretion in hypoxic ischemic encephalopathy.

Neuro Endocrinol Lett 2018 Dec;39(5):391-400

Department of Medical Physics, Maria Skłodowska- Curie Memorial Cancer Center and Institute of Oncology Gliwice Branch, Poland.

Objectives: The aims of the study were to assess the kinematics of the lower limbs and pelvis during normal walking in professional ballet dancers and to investigate relationships between movements of segments of the lower limbs and pelvis.

Methods: Thirty one professional ballet dancers and twenty eight controls completed five walking trials at their preferred speed. Kinematic data in the basic anatomical planes for ankle, knee, and hip joints as well as for the pelvis were collected with an optoelectronic motion system. Read More

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December 2018
4 Reads

Comparison of gait kinematics between professional ballet dancers and non-dancers.

Neuro Endocrinol Lett 2018 Dec;39(5):385-390

Faculty of Medicine, University of Ostrava, Ostrava,, Czech Republic.

Objectives: The aims of the study were to assess the kinematics of the lower limbs and pelvis during normal walking in professional ballet dancers and to investigate relationships between movements of segments of the lower limbs and pelvis.

Methods: Thirty one professional ballet dancers and twenty eight controls completed five walking trials at their preferred speed. Kinematic data in the basic anatomical planes for ankle, knee, and hip joints as well as for the pelvis were collected with an optoelectronic motion system. Read More

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December 2018
5 Reads

Accumulation of selected metals pollution in aquatic ecosystems in the Smeda river (Czech republic).

Neuro Endocrinol Lett 2018 Dec;39(5):380-384

University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Institute of Aquaculture and Protection of waters, Czech Republic.

Objectives: Biomonitoring of some slelected heavy metals in the Smeda river (Czech Republic) was carried out during 2015-2016 to assess the extent of environmental pollution. Attempts were also made to map the intensity of bioaccumulation in brown trout which was used as an indicator species. Monitoring of the environmental pollution of the Smeda river was carried in 2016. Read More

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December 2018
2 Reads

Sequencing of the insulin receptor (INSR) gene reveals association between gene variants in exon and intron 13 and schizoaffective disorder.

Neuro Endocrinol Lett 2018 Dec;39(5):371-379

Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.

Objectives: From the hypothesis that an impaired insulin and insulin-like growth factor cellular signalling in brain and body might result in the development of schizophrenia or related psychoses, I in this study chose to thoroughly investigate the insulin receptor gene in patients with schizophrenia or schizoaffective disorder and controls.

Methods: For identification of single nucleotide polymorphisms (SNPs) of interest in the insulin receptor gene, targeted whole gene sequencing of DNA using the SOLiD technology was first carried out in two subgroups of the study population: 1) 49 schizophrenia or schizoaffective disorder patients with heredity for schizophrenia or related psychoses, and 2) 25 controls. Ten possible SNPs of interest were identified and these were then typed by standard methods in the whole study population consisting of 105 patients with schizophrenia or schizoaffective disorder and 60 controls. Read More

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December 2018
3 Reads

Mu Opioid Receptor Regulation of Gonadotropin-Releasing Hormone-Luteinizing Hormone Axis during Short-Term Food Deprivation: Role of Alpha1-Adrenoreceptor Signaling.

Neuro Endocrinol Lett 2018 Dec;39(5):363-370

School of Basic Pharmaceutical and Toxicological Sciences, College of Pharmacy, University of Louisiana Monroe, Monroe, LA 71201, USA.

Objectives: Brain bio-energetic stability is required for optimal gonadal steroid positive-feedback activation of the gonadotropin-releasing hormone-I (GnRH-I)-pituitary luteinizing hormone (LH) neuroendocrine axis. Caudal hindbrain metabolic-sensory noradrenergic neurons counter energy deficiency by curtailing the mid-cycle LH surge. Central mu opioid receptors (mu-R) impose inhibitory effects of diverse physiological stimuli, including stress, on LH. Read More

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December 2018
6 Reads

Insulin resistance - "the good or the bad and ugly".

Neuro Endocrinol Lett 2018 Dec;39(5):355-362

Department of Endocrinology and Metabolic Diseases, Medical University of Lodz, Polish Mother's Memorial Hospital - Research Institute, Lodz, Poland.

Insulin resistance (IR) is a state of decreased sensitivity or responsiveness of target tissues to metabolic actions of circulating insulin. IR can be selective, involving only certain aspects of insulin action, i.e. Read More

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December 2018
2 Reads

Encephalitis with anti-NMDA receptor antibodies: paraneoplastic or non-paraneoplastic?

Neuro Endocrinol Lett 2018 Dec;39(5):351-354

Department of Neurology, Charles University in Prague, Faculty of Medicine in Hradec Kralove and University Hospital, Hradec Kralove, Czech Republic.

We report the case of an encephalitis patient with anti-N-methyl-D-aspartate receptor (NMDAR) antibody positivity. Anti-NMDAR encephalitis is a relatively rare autoimmune disease. In our patient, the diagnosis of anti-NMDAR encephalitis was established as late as several months after the first manifestations of the condition. Read More

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December 2018
2 Reads

Three diagnostic psychiatric subgroups in comparison to self-stigma, quality of life, disorder severity and coping management cross-sectional outpatient study.

Neuro Endocrinol Lett 2018 Oct;39(4):331-341

Department of Psychiatry, Faculty of Medicine and Dentistry, Palacky University Olomouc, and University Hospital Olomouc, Czech Republic.

Background: Much attention has been paid to psychological factors influencing characteristics, severity, and course of mental disorders. The objective of our investigation was to examine the interrelations among quality of life (QoL), self-stigma, and coping strategies, demographics and severity of the disorder in neurotic spectrum disorders, schizophrenia, and depressive spectrum disorders.

Methods: A total of 343 clinically stable Czech outpatients with different mental disorders (153 with neurotic spectrum disorders; 81 with depression, and 109 with schizophrenia spectrum disorders) were included. Read More

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October 2018
2 Reads

The effect of silver nanoparticles and silver ions on zebrafish embryos (Danio rerio).

Neuro Endocrinol Lett 2018 Oct;39(4):299-304

Department of Animal Protection, Welfare and Behaviour, Faculty of Veterinary Hygiene and Ecology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czech Republic.

Objectives: The aim of this study was to establish and evaluate the mortality rate, hatching rate and observe the presence of sublethal changes in zebrafish embryos after exposure to silver ions and nanoparticles.

Methods: Tests were conducted on newly fertilized zebrafish embryos, according to the modified OECD guideline 236, using a semistatic method and 96 hour incubation time. Silver nitrate and two different silver nanoparticles, stabilized with 0. Read More

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October 2018
4 Reads

The assessment of retina in pregnant women with myopia.

Neuro Endocrinol Lett 2018 Oct;39(4):321-324

Department of Ophthalmology, Military Institute of Medicine, Warsaw, Poland.

Objectives: Myopia is associated with increased frequency of retinal degenerative changes which are the risk factors of intra- and postpartal ophthalmological complications. Aim of this study was to analyze the degenerative lesions detected in opthalmological examination (including peripheral retinal lesions) as a potential risk factors for eyes' status in terms of delivery in myopic women.

Material And Methods: 254 pregnant women affected with myopia underwent opthalmological examination as a screening method to examine retina. Read More

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October 2018
1 Read

Regional differences in somatostatin receptor 2 (SSTR2) immunoreactivity is coupled to level of bowel invasion in small intestinal neuroendocrine tumors.

Neuro Endocrinol Lett 2018 Oct;39(4):305-309

Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.

Objective: Somatostatin receptor (SSTR) expression constitutes a pivotal cornerstone for accurate radiological detection and medical treatment of small intestinal neuroendocrine tumors (SI-NETs), and the development of somatostatin analogues for these purposes have revolutionized the clinical work-up. Previous assessments of SSTR isoform expression in SI-NETs have found correlations to overall prognosis and treatment response, however these analyses usually report overall tumoral immunoreactivity, and little is reported regarding histo-regional differences in expressional patterns.

Methods: Thirty-seven primary SI-NETs (WHO grade I, n=32 and WHO grade II, n=5) were collected and assessed for SSTR2 immunohistochemistry. Read More

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October 2018
1 Read
0.935 Impact Factor

Locomotion in young rats with induced brain cellular edema - effects of recombinant human erythropoietin.

Neuro Endocrinol Lett 2018 Oct;39(4):310-314

Institute of Physiology, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.

Objectives: Effect of recombinant human erythropoietin (rhEPO) on spontaneous motor activity was tested in young rats after intraperitoneal (i.p.) administration of rhEPO, followed by induction of cellular brain edema (CE). Read More

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October 2018
2 Reads

Light-dark influence on enkephalinase activity in hypothalamus and pituitary.

Neuro Endocrinol Lett 2018 Oct;39(4):277-280

Unit of Physiology, University of Jaén, 23071 Jaén, Spain.

Objectives: Enkephalins functions are partly modulated by enkephalinases especially membrane-bound alanyl aminopeptidase (EC-3.4.11. Read More

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October 2018
4 Reads

Levels of selected contaminants in fish muscle from upper Nitra River.

Neuro Endocrinol Lett 2018 Oct;39(4):315-320

University of South Bohemia in Ceske Budejovice, Faculty of Fisheries and Protection of Waters, South Bohemian Research Center of Aquaculture and Biodiversity of Hydrocenoses, Institute of Aquaculture and Protection of waters, Ces, Czech Republic.

Objectives: This study determines the levels of selected contaminants in the muscle of three common fish species from the upper course of the Nitra River.

Design: Were detected levels of Zn, Cu, Ni, Cr, Pb, Cd and Hg in the muscle and correlations among selected metals as well as standard length and total weight in brown trout (Salmo trutta morpha fario), Alpine bullhead (Cottus poecilopus) and grayling (Thymallus thymallus).

Results: The content of analysed metals (mg. Read More

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October 2018
1 Read

Human mature milk zearalenone and deoxynivalenol levels in Turkey.

Neuro Endocrinol Lett 2018 Oct;39(4):325-330

Eskisehir Osmangazi University Faculty of Medicine, Department of Pediatric Neurology, Eskisehir, Turkey.

Introduction: Zearalenone (ZEA) and deoxynivalenol (DON) are toxic fungal secondary metabolites, found mainly in contaminated food, that are associated with serious health problems. It is important to identify undesirable toxins and metabolites that may be present in human milk. The aim of this study was to evaluate human milk ZEA and DON levels, total daily intake of ZEA and DON; and their possible relationship with maternal dietary habits. Read More

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October 2018
14 Reads

Gamma knife radiosurgery for local recurrence of glioblastoma.

Neuro Endocrinol Lett 2018 Oct;39(4):281-287

Department of Medical Physics, Na Homolce Hospital, Prague, Czech Republic.

Objective: Local recurrence of glioblastoma is observed in most patients after standard oncologic treatment (surgery, chemotherapy and radiotherapy). Stereotactic radiosurgery with the Leksell Gamma Knife (SRS with LGK) was used to treat recurrent tumors in selected cases, and retrospective analysis of treatment outcome was performed.

Methods: Altogether 126 patients were treated for glioblastoma at our center from 1992-2014. Read More

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October 2018
4 Reads

Endocrine response to high intensity barbell squats performed with constant movement tempo and variable training volume.

Neuro Endocrinol Lett 2018 Oct;39(4):342-348

Charles University in Prague, Faculty of Physical Education and Sport, Department of Sport Games, Prague, Czech Republic.

Objective: Research indicates that among the many elements of resistance exercise protocols, training volume and total training load are the key factors for post-exercise increase in the secretion of testosterone (T), growth hormone (GH), insulin-like growth factor (IGF-1) and cortisol (C). The aim of this study was to determine the effects of resistance exercises with variable volume and constant intensity and movement tempo on post-exercise concentrations of selected anabolic and catabolic hormones.

Materials And Methods: 28 experienced powerlifters (27. Read More

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October 2018
1 Read

Depressive symptoms are associated with higher morning plasma cortisol in primary care subjects.

Neuro Endocrinol Lett 2018 Oct;39(4):288-293

Endocrinology Department, School of Medicine, Pontificia Universidad Catolica de Chile, Santiago, Chile.

Background: Cortisol dysregulation has a potential role in depression.

Aim And Methods: We evaluated depressive symptoms using the Hamilton Rating Scale for Depression in 48 primary care subjects without history of previous or current depression and its association with cortisol dysregulation (morning plasma cortisol, 24-hour urinary free cortisol and cortisol metabolites). Presence of metabolic syndrome and inflammatory parameters were also assessed. Read More

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October 2018
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Bisphenol A as an environmental pollutant with dual genotoxic and DNA-protective effects.

Neuro Endocrinol Lett 2018 Oct;39(4):294-298

Department of Genetics, Faculty of Natural Sciences, Comenius University, Bratislava, Slovakia.

Objectives: Bisphenol A (BPA) is an endocrine disruptor which has been shown to be a harmful compound for living organisms. It is the main component of the most commonly used plastic products such as plastic bottles, food cans and containers or dental fillings, and other medical aids. Recently, it has become a new environmental pollutant. Read More

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October 2018
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The over-expression of GH/GHR in tumour tissues with respect to healthy ones confirms its oncogenic role and the consequent oncosuppressor role of its physiological inhibitor, somatostatin: a review of the literature.

Neuro Endocrinol Lett 2018 Sep;39(3):179-188

Di Bella Foundation, Via Guglielmo Marconi 51 Bologna, 40122, Italy.

The interaction between pituitary hormones, GH - PRL, and Growth Factors, GF, plays a fundamental role in the physiological and neoplastic mechanisms of growth, the latter using these factors to a much greater extent compared to the former, with a direct dose-dependent effect on the speed of local or metastatic expansion. In hormone-dependent tumours, the respective male and female sex hormones interact with GH - PRL - GF to sustain the expansion of the tumour. We carried out a review of the literature on the relationship between the expression of GH and GHR in tumour tissues compared to healthy tissues, and on the correlation between this expression and tumour aggressiveness. Read More

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September 2018
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Revisiting respiratory muscle strength and pulmonary function in spinal cord injury: The effect of body positions.

Neuro Endocrinol Lett 2018 Sep;39(3):189-195

Department of Rehabilitation Medicine, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Republic of Korea.

Objectives: In the subjects with high cervical spinal cord injury (SCI), The difference of respiratory muscle strength and pulmonary function according to supine and sitting position were investigated whether there are changes in the tendency.

Methods: Twenty-three subjects with high cervical SCI and 23 subjects with low cervical and thoracic SCI were evaluated. The reference neurological level of injury for dividing the groups was fifth cervical vertebrae (C5). Read More

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September 2018
18 Reads

Personality disorder in marriage and partnership - a narrative review.

Neuro Endocrinol Lett 2018 Sep;39(3):159-171

Department of Psychiatry, Faculty of Medicine and Dentistry, University Palacky Olomouc, University Hospital, 77520 Olomouc, Czech Republic.

Background: Partner conflicts are the most common precipitating factors of decompensation of psychiatric disorders, including personality disorders. Personal characteristics play a fundamental role in both the prediction of marital satisfaction of the individual as well as the satisfaction of the couple as a whole.

Method: Narrative Review of the articles, books and book chapters within the period 1956 - 2016 using PubMed, Web of Science, and Scopus databases with keywords "personality disorder," "partnership," marital problems," "marital conflicts. Read More

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September 2018
15 Reads

Neuroendocrine aspects of anorexia nervosa and bulimia nervosa.

Neuro Endocrinol Lett 2018 Sep;39(3):172-178

Department of Neurology, Medical University of Warsaw, Bielanski Hospital, Warsaw,, Poland.

Endocrine dysfunctions in eating disorders (anorexia nervosa, bulimia nervosa) result from disturbed regulation of hypothalamo-pituitary-gonadal, hypothalamo-pituitary-adrenal, hypothalamo-pituitary-thyroid and hypothalamo-pituitary-GH-IGF1 axes as well as of altered peripheral endocrine metabolism. Some peptides of hypothalamic origin, as well as those secreted by the adipose tissue and gastrointestinal tract including pancreatic hormones, are involved in the control of appetite and satiety. These peptides play also an important role in the mechanism of hormonal secretion. Read More

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September 2018
24 Reads

Hypophysitis and other autoimmune complications related to immune checkpoints inhibitors´ treatment: Spectrum of imaging appearances.

Neuro Endocrinol Lett 2018 Sep;39(3):196-204

Radiology Department, Third Faculty of Medicine, Charles University, Faculty Hospital Kralovske Vinohrady, Prague, Czech Republic.

Objectives: Immune checkpoints inhibitors (ICI) represent a new therapy option for the treatment of several advanced tumors. However, this therapy has been linked to a spectrum of ICI related autoimmune (AI) adverse events. Some may be life threatening and their diagnosis is tricky. Read More

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September 2018
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Coexistence of neurofibromatosis type 1 with multiple malignant neoplasia.

Neuro Endocrinol Lett 2018 Sep;39(3):149-155

Clinical Department of Endocrinology, Jagiellonian University in Krakow, Poland.

Neurofibromatosis type 1 (NF1, von Recklinghausen disease) is inherited in autosomal dominant way genetic disorder, with an incidence at birth 1:3000. It is one of the most common congenital disorders. It is characterized by café-au-lait spots, neurofibromas, and less common MPTST and gliomas of the optic nerve. Read More

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September 2018
20 Reads