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    Voluminous laryngeal schwannoma excision with a mini-invasive external approach: a case report.
    Acta Otorhinolaryngol Ital 2017 Jun;37(3):242-244
    Department of Otolaryngology Head and Neck Surgery, San Raffaele Scientific Institute, Milan, Italy.
    Laryngeal schwannomas are extremely uncommon. We present a case of bulky supraglottic schwannoma with involvement of the preepiglottic and superior paraglottic spaces. Clinical findings, computed tomography and magnetic resonance images are presented. Read More

    Intraoral neurilemmoma of mental nerve mimicking as traumatic fibroma: An unusual presentation - A case report and literature review.
    J Oral Maxillofac Pathol 2017 Jan-Apr;21(1):124-128
    Department of Oral and Maxillofacial Pathology, Faculty of Dental Sciences, Sri Ramachandra Medical Centre, Chennai, Tamil Nadu, India.
    Neurilemmoma, neurinoma or schwannoma is a benign tumor of neurogenic origin, arising from the myelin sheath of a neuron. Head and neck region accounts for 25%-48% of these tumors reported till date. On the contrary, intraoral sites form only 1% of the cases accounted. Read More

    Small palatal swelling: an uncommon presentation of intraoral schwannoma.
    Gen Dent 2017 May-Jun;65(3):58-61
    Schwannomas are uncommon benign tumors arising in the nerve-supporting Schwann cells. Intraoral lesions usually present in the tongue or floor of the mouth as a submucosal nodule, while the palate is rarely affected. A 26-year-old white man presented with an asymptomatic submucosal fibroelastic nodule in the hard palate. Read More

    Hypoxia-induced miR-210 promoter demethylation enhances proliferation, autophagy and angiogenesis of schwannoma cells.
    Oncol Rep 2017 May 16;37(5):3010-3018. Epub 2017 Mar 16.
    Department of Orthopaedic Surgery, The Third Xiangya Hospital of Central South University, Changsha, Hunan 410011, P.R. China.
    Hypoxia, a dominant feature in cancer occurrence and evolution, exists throughout the progression of most malignant tumors. This study focused on the mechanism of hypoxia-induced miR-210 upregulation, and the miR-210 functions in schwannoma. We detected microvascular density, vascular endothelial growth factor (VEGF) and miR-210 expression levels using schwannoma tissue mciroarray. Read More

    Generation of a human induced pluripotent stem cell (iPSC) line from a 64year old male patient with multiple schwannoma.
    Stem Cell Res 2017 Mar 21;19:49-51. Epub 2016 Dec 21.
    Department of Ophthalmology, The 2nd Hospital of Jilin University, Changchun 130041, China.
    Peripheral blood was collected from a clinically diagnosed 64-year old male multiple schwannoma patient. Peripheral blood mononuclear cells (PBMCs) were reprogrammed with the Yamanaka KMOS reprogramming factors using the Sendai-virus reprogramming system. The transgene-free iPSC line showed pluripotency verified by immunofluorescent staining for pluripotency markers, and the iPSC line was able to differentiate into the 3 germ layers in vivo. Read More

    Development of human induced pluripotent stem cell (iPSC) line from a 60year old female patient with multiple schwannoma.
    Stem Cell Res 2017 Mar 23;19:31-33. Epub 2016 Dec 23.
    Department of Ophthalmology, The 2nd Hospital of Jilin University, Changchun 130041, China.
    Peripheral blood was collected from a clinically diagnosed 60-year old female patient with multiple schwannoma. Peripheral blood mononuclear cells (PBMCs) were reprogrammed with the Yamanaka KMOS reprogramming factors using the Sendai-virus reprogramming system. The transgene-free iPSC line showed pluripotency verified by immunofluorescent staining for pluripotency markers, and the iPSC line was able to differentiate into the 3 germ layers in vivo. Read More

    Giant Schwannoma of ulnar nerve: case report.
    Rev Bras Ortop 2017 Mar-Apr;52(2):224-227. Epub 2016 Sep 20.
    Centro Hospitalar São João, Porto, Portugal.
    Schwannomas are the most common benign neoplasms of the peripheral nerves in the upper limbs. Although many are asymptomatic, they can produce a mass effect, thus impinging against soft tissues or interfering with joint function. The authors present a case report and a review of a giant Schwannoma in the ulnar nerve. Read More

    Approaches to paraspinal tumours - a technical note.
    Neurol Res 2017 Apr 23;39(4):315-322. Epub 2017 Mar 23.
    a Lilavati Hospital and Research Centre , Mumbai , India.
    Neurogenic tumours of the paraspinal space can occur in all age groups. It is common in adult population and relatively rare in elderly group. Usually they are benign, but in children, arising from the autonomic system, tends to be malignant in nature. Read More

    A rare thoracic intraspinal schwannoma in twin pregnancy with aggravated clinical presence: A case report following CARE.
    Medicine (Baltimore) 2017 Mar;96(11):e6327
    aDepartment of Neurosurgery, West China Hospital bDepartment of Nursing, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
    Introduction: This is the first case report about a thoracic intraspinal schwannoma in twin pregnancy with aggressive clinical presentation.

    Clinical Presence And Diagnoses: A 21-year-old woman presented with a 2-month history of back pain and slight lower extremity numbness and weakness, and her symptoms were misdiagnosed as normal reactions to pregnancy until she progressed to complete paralysis and incontinence within 2 weeks. She was then confirmed to have thoracic intraspinal schwannoma through MRI. Read More

    Laparoscopic resection of retroperitoneal benign neurilemmoma.
    Ann Surg Treat Res 2017 Mar 24;92(3):149-155. Epub 2017 Feb 24.
    Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.; Pancreaticobiliary Cancer Clinic, Yonsei Cancer Center, Institute of Gastroenterology Severance Hospital, Seoul, Korea.
    Purpose: The aim of this study was to verify that laparoscopic resection for treating retroperitoneal benign neurilemmoma (NL) is expected to be favorable for complete resection of tumor with technical feasibility and safety.

    Methods: We retrospectively analyzed 47 operations for retroperitoneal neurogenic tumor at Yonsei University College of Medicine, Severance Hospital and Gangnam Severance Hospital between January 2005 and September 2015. After excluding 21 patients, the remaining 26 were divided into 2 groups: those who underwent open surgery (OS) and those who underwent laparoscopic surgery (LS). Read More

    Intraconal optic sheath schwannoma: report of two cases.
    Br J Neurosurg 2017 Mar 10:1-3. Epub 2017 Mar 10.
    c Department of Pathology , Bombay Hospital Institute of Medical Sciences & Research Centre , Mumbai , India.
    Optic sheath schwannoma is extremely rare. We discuss two cases of intraorbital intraconal optic sheath schwannoma. Vision significantly improved in both patients following the surgery. Read More

    Peripheral Nerve Schwannoma: A Review of Varying Clinical Presentations and Imaging Findings.
    J Foot Ankle Surg 2017 May - Jun;56(3):632-637. Epub 2017 Feb 22.
    Physician, Medical Arts Radiology, Commack, NY.
    A schwannoma or neurilemmoma is a benign, isolated, noninvasive, and encapsulated tumor originating from Schwann cells of the peripheral nerve sheath. The incidence of a schwannoma occurring in the foot and ankle is rare, with prevalence rate of 1% to 10%. Schwannomas have no sex predilection, and they commonly occur in patients in their fourth decade. Read More

    Colonic Schwannoma: A Case Study and Literature Review of a Rare Entity and Diagnostic Dilemma.
    Am Surg 2016 Dec;82(12):1183-1186
    Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.
    An asymptomatic 73-year-old woman was found to have a submucosal mass in the descending colon on routine colonoscopy. A CT scan revealed a 31 × 28 × 31 mm lesion in the same location. Previous biopsy proved to be nondiagnostic, and the patient underwent a laparoscopic descending colon resection. Read More

    Solid-Cystic Hypoglossal Nerve Schwannoma with Fluid-Fluid Level: A Rare Case Report.
    J Clin Diagn Res 2016 Dec 1;10(12):TD06-TD08. Epub 2016 Dec 1.
    Resident, Department of Radiology, Krishna Hospital and Medical Research Center , Karad, Maharashtra, India .
    Schwannomas (neurinoma, neurilemmoma) are benign slow-growing encapsulated tumours originating from well-differentiated myelin-producing Schwann cells or nerve fiber sheet cells at the glial-Schwann cell junction. Hypoglossal nerve schwannoma mostly develops in the intracranial and extra-cranial segment or in both intracranial and extra-cranial segment forming a dumbbell shape tumour. The peripheral hypoglossal schwannomas are very rare. Read More

    Schwannoma of the tongue-A common tumour in a rare location: A case report.
    Eur J Radiol Open 2017 1;4:1-3. Epub 2017 Feb 1.
    Serviço de Imagem Médica - Centro Hospitalar Universitário de Coimbra, Praceta Mota Pinto, 3000-075 Coimbra, Portugal.
    Schwannoma is a benign tumour that arises from Schwann cells of the peripheral nerve sheath, and is a common tumour of the head and neck. However, intraoral location is very uncommon (only 1% of all head and neck schwannomas). We report a rare case of lingual schwannoma in a 20-year-old male patient who presented with a small, slow-growing mass over the right lateral border of the tongue with 1 year of evolution and that became recently ulcerated. Read More

    A non-surgical approach to the management of exposure keratitis due to facial palsy by using mini-scleral lenses.
    Medicine (Baltimore) 2017 Feb;96(6):e6020
    Lexington Eye Associates, Westford, MA.
    Rationale: This is a retrospective study aimed to determine the efficacy of mini-scleral contact lens in protecting the cornea and improving vision in cases of facial palsy.

    Patient Concerns: Patients with facial palsy get exposure keratitis because the cornea is dry. They feel pain, discomfort and excessive watering. Read More

    Lateral skull base surgery in a pediatric population: A 25-year experience in a referral skull base center.
    Int J Pediatr Otorhinolaryngol 2017 Mar 14;94:70-75. Epub 2017 Jan 14.
    Department of Otology & Skull Base Surgery, Gruppo Otologico, Piacenza, Rome, Italy.
    Objective: To analyze the pathology and surgical outcomes of lateral skull base (LSB) procedures in a pediatric population.

    Study Design: Retrospective case review in a referral skull base center.

    Methods: Charts of pediatric patients who underwent defined LSB procedures from 1983 to 2015 for various pathologies were evaluated at our center. Read More

    Inter-observer variability between radiologists reporting on cerebellopontine angle tumours on magnetic resonance imaging.
    J Laryngol Otol 2017 Jan;131(S1):S47-S49
    Department of Otolaryngology,St Vincent's Private Hospital,Sydney,Australia.
    Background: Studies demonstrate the significance of intra- and inter-observer variability when measuring cerebellopontine angle tumours on magnetic resonance imaging, with measured differences as high as 2 mm.

    Objective: To determine intra- and inter-observer measurement variability of cerebellopontine angle tumours in a specialised institution.

    Methods: The magnetic resonance imaging maximal diameter of 12 randomly selected cerebellopontine angle tumours were independently measured by 4 neuroradiologists at a tertiary referral centre using a standard definition for maximal tumour diameter. Read More

    Patients with benign hand tumors are indicated for surgery according to patient-rated outcome measures.
    J Plast Reconstr Aesthet Surg 2017 Apr 9;70(4):487-494. Epub 2017 Jan 9.
    Department of Hand Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.
    Introduction: This study assessed the treatment outcomes of upper extremity benign tumors using the patient-rated outcome measures of Hand20 questionnaire.

    Methods: In total, 304 patients who underwent surgery for benign bone and soft tissue tumors of the upper limb were included. Tumors were classified into three size groups: <1 cm, 1-3 cm, and >3 cm. Read More

    Functional outcome and complications after the microsurgical removal of giant vestibular schwannomas via the retrosigmoid approach: a retrospective review of 16-year experience in a single hospital.
    BMC Neurol 2017 Jan 31;17(1):18. Epub 2017 Jan 31.
    Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, 200040, People's Republic of China.
    Background: Intracranial vestibular schwannoma still remain to be difficulty for its unique microsurgical technique and preservation of neuro-function, as well as reducing common complications that may arise in surgery.

    Methods: We consecutively enrolled 657 unilateral giant (>4 cm diameter) vestibular schwannoma patients treated in Huashan Hospital via the suboccipital retrosigmoid approach in the past 16 years. The extension of tumor removal, surgical mortality, facial nerve function, hearing, and the other main short and long-term complications were the studied parameters. Read More

    Global Proteome and Phospho-proteome Analysis of Merlin-deficient Meningioma and Schwannoma Identifies PDLIM2 as a Novel Therapeutic Target.
    EBioMedicine 2017 Feb 18;16:76-86. Epub 2017 Jan 18.
    Institute of Translational and Stratified Medicine, Plymouth University Peninsula Schools of Medicine and Dentistry, John Bull Building, Plymouth Science Park, Research Way, Derriford, Plymouth PL6 8BU, UK. Electronic address:
    Loss or mutation of the tumour suppressor Merlin predisposes individuals to develop multiple nervous system tumours, including schwannomas and meningiomas, sporadically or as part of the autosomal dominant inherited condition Neurofibromatosis 2 (NF2). These tumours display largely low grade features but their presence can lead to significant morbidity. Surgery and radiotherapy remain the only treatment options despite years of research, therefore an effective therapeutic is required. Read More

    Comparison between MR imaging findings of intracranial and extracranial schwannomas.
    Clin Imaging 2017 Mar - Apr;42:218-223. Epub 2017 Jan 16.
    Department of Radiology, Gifu University School of Medicine, 1-1 Yanagido, Gifu 501-1194, Japan.
    Purpose: To evaluate the differences of MR imaging findings between intracranial and extracranial schwannomas.

    Methods: We retrospectively reviewed the MR images of 98 schwannomas and compared the imaging findings between intracranial and extracranial schwannomas.

    Results: The number of intratumoral cysts was greater in intracranial than in extracranial schwannomas (4. Read More

    Epithelioid schwannoma of the skin displaying unique histopathological features: a teaching case giving rise to diagnostic difficulties on a morphological examination of a resected specimen, with a brief literature review.
    Diagn Pathol 2017 Jan 19;12(1):11. Epub 2017 Jan 19.
    Department of Pathology, Field of Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.
    Background: Epithelioid schwannoma as a rare variant poses a challenge to all pathologists, as this uncommon entity is extremely difficult to conclusively diagnose by morphological analyses on a resected sample alone owing to its unique histopathological features. However, few papers have described the detailed clinicopathological characteristics of epithelioid schwannoma.

    Case Presentation: A 65-year-old female presented with a history of a flat and slightly elevated firm and tan plaque accompanied by occasional tenderness, measuring 10 × 8 mm, in the right joint of her hand 1 year before resection. Read More

    Supra and infratentorial ectopic schwannoma mimicking a meningioma.
    BMJ Case Rep 2017 Jan 17;2017. Epub 2017 Jan 17.
    Department of Neurosurgery, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal.
    We report the case of a supra and infratentorial ectopic schwannoma, mimicking a meningioma, that was surgically resected on a 75-year-old man, with a history of progressive visual loss and headaches. MRI was in favour of an occipital, cystic, tentorial-based meningioma extending to the posterior fossa, with signs of intratumoral haemorrhage. This is a unique case because of the rare type of lesion, in a very atypical location, completely unexpected by the preoperative imaging analysis, and to the best of our knowledge it is the oldest patient reported in the literature with this kind of tumour. Read More

    Schwannoma of the Recurrent Laryngeal Nerve: A Rare Entity.
    Innovations (Phila) 2017 Jan/Feb;12(1):64-66
    From the Departments of *Cardiothoracic Surgery, †Pulmonology, and ‡Pathology, University Medical Central Utrecht, Utrecht, The Netherlands.
    Neurogenic tumors are the most common posterior mediastinal tumors in adults. Schwannomas originating from the recurrent laryngeal nerve are rare. The present study describes a 46-year-old man with a tumor in the left superior mediastinum. Read More

    Clinical outcomes following resection of giant spinal schwannomas: a case series of 32 patients.
    J Neurosurg Spine 2017 Apr 13;26(4):494-500. Epub 2017 Jan 13.
    Department of Neurological Surgery, Memorial Sloan Kettering Cancer Center.
    OBJECTIVE The objective of this study was to review clinical outcomes following resection of giant spinal schwannomas. METHODS The authors conducted a retrospective review of a case series of patients with giant spinal schwannomas at a tertiary cancer hospital. RESULTS Thirty-two patients with giant spinal schwannomas underwent surgery between September 1998 and May 2013. Read More

    Concomitant orbital cavernous haemangioma and schwannoma in a patient.
    BMJ Case Rep 2017 Jan 12;2017. Epub 2017 Jan 12.
    Apollo Health City, Hyderabad, India.
    A woman aged 39 years presented with right eye painless proptosis and decreased vision since 5 months. Right fundus examination revealed optic disc oedema. CT of the orbit revealed a well-defined homogeneous mass in the intraconal space in both orbits. Read More

    Rediagnosing one of Smith's patients (John McCann) with "neuromas tumours" (1849).
    Neurol Sci 2017 Mar 11;38(3):493-499. Epub 2017 Jan 11.
    National Centre for Rare Diseases, Istituto Superiore di Sanità, Rome, Italy.
    In 1849, the Irish Professor of Surgery, Sir Robert William Smith, by publishing his "Treatise on the Pathology, Diagnosis and Treatment of Neuroma", collected six previous examples of "general development of neuromatous tumours" and reported three further cases (two personal and one referred) of what is nowadays known as neurofibromatosis. Among these latter cases, there was a 35-year-old cattle-driver, John McCann, who was first admitted at hospital in 1840 because of a large tumour on the right side of his neck thought to be malignant (and a second tumour sublingually) but not operated. McCann was readmitted in 1843 ("in an emaciated state"), because of an immense tumour in his thigh dying few months later "with hepatic symptoms". Read More

    [Schwannoma of the Upper Extremity: Retrospective Analysis of 17 Cases].
    Acta Med Port 2016 Sep 30;29(9):519-524. Epub 2016 Sep 30.
    Serviço de Cirurgia Plástica, Reconstrutiva e Maxilo-Facial. Hospital Egas Moniz. Centro Hospitalar de Lisboa Ocidental. Lisboa. Portugal.
    Introduction: Schwannoma or neurilemmoma is a benign peripheric nerve tumor that usually presents as a slow growing single lesion; it has origin in Schwann cells proliferation. Although it represents a small percentage of the benign tumors of the upper arm, it is the most frequent of neural origin. We present a retrospective study of upper limb schwannomas; our aim is establish the appropriate preoperative approach, to recognise the efficiency of the treatment and the pos-operative follow-up. Read More

    Vertigo Perception and Quality of Life in Patients after Surgical Treatment of Vestibular Schwannoma with Pretreatment Prehabituation by Chemical Vestibular Ablation.
    Biomed Res Int 2016 8;2016:6767216. Epub 2016 Dec 8.
    Department of Neurology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Postgraduate Medical School, Prague, Czech Republic.
    Surgical removal of vestibular schwannoma causes acute vestibular symptoms, including postoperative vertigo and oscillopsia due to nystagmus. In general, the dominant symptom postoperatively is vertigo. Preoperative chemical vestibular ablation can reduce vestibular symptoms postoperatively. Read More

    Outcomes of Treatment for Malignant Peripheral Nerve Sheath Tumors: Different Clinical Features Associated with Neurofibromatosis Type 1.
    Cancer Res Treat 2016 Dec 1. Epub 2016 Dec 1.
    Division of Pediatric Hemato-oncology, Department of Pediatrics, Yonsei University College of Medicine, Yonsei University Health System, Seoul, Korea.
    Purpose: Malignant peripheral nerve sheath tumors (MPNSTs) are a rare subtype of sarcoma that occur spontaneously or in association with neurofibromatosis type 1 (NF-1). This study aimed to clinically differentiate these types of MPNSTs.

    Materials And Methods: The study reviewed 95 patients diagnosed with and treated for MPNST at Yonsei University Health System, Seoul, Korea over a 27-year period. Read More

    [Maxillary trigeminal schwannoma. Presentation of a case and review of literature].
    Cir Cir 2016 Dec 30. Epub 2016 Dec 30.
    Servicio de Neurocirugía, Hospital General Balbuena, Ciudad de México, México.
    Introduction: Schwannomas are benign tumours that are relatively common in the head, however the involvement of the sinunasal region is rare and there are only 5 cases reported in the maxilla in current literature, representing less than 1% of bone tumours.

    Clinical Case: We report the case of a woman with a right maxillary schwannoma who underwent a complete resection of the lesion. Emphasis is placed on the rarity of the lesion in terms of its location and includes a review of clinical behaviour, diagnosis and current treatment options. Read More

    Stereotactic radiosurgery planning of vestibular schwannomas: Is MRI at 3 Tesla geometrically accurate?
    Med Phys 2017 Feb;44(2):375-381
    Neuro-Oncology Unit, Royal Marsden NHS Foundation Trust, London, UK.
    Purpose: MRI is a mandatory requirement to accurately plan Stereotactic Radiosurgery (SRS) for Vestibular Schwannomas. However, MRI may be distorted due not only to inhomogeneity of the static magnetic field and gradients but also due to susceptibility-induced effects, which are more prominent at higher magnetic fields. We assess geometrical distortions around air spaces and consider MRI protocol requirements for SRS planning at 3 T. Read More

    Suspected Acoustic Neuroma Demyelinating Lesions.
    J Craniofac Surg 2016 Nov;27(8):e747-e748
    *Department of Neurosurgery, Clinical Medicine College of Anhui Medical University, Shenzhen Second People's Hospital†Shenzhen Key Laboratory of Neurosurgery, Shenzhen, China.
    Demyelinating lesions were recognized as a kind of rare central nervous system demyelinating lesion. The diagnosis and differential diagnosis of demyelinating lesions is difficult. Once the diagnosis was delayed or incorrect, it will make a great impact on patients. Read More

    Tumor Occupation in the Spinal Canal and Clinical Symptoms of Cauda Equina Schwannoma: An Analysis of 22 Cases.
    Asian Spine J 2016 Dec 8;10(6):1079-1084. Epub 2016 Dec 8.
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
    Study Design: Retrospective, radiological study.

    Purpose: To determine the relationship between clinical symptoms and the extent of tumor occupation of the spinal canal by cauda equina schwannoma.

    Overview Of Literature: Little is known about the relationship between the size of tumors of the cauda equina and the manifestation of clinical symptoms. Read More

    The response of spinal cord ependymomas to bevacizumab in patients with neurofibromatosis Type 2.
    J Neurosurg Spine 2017 Apr 16;26(4):474-482. Epub 2016 Dec 16.
    Nuffield Department of Neurosciences and NF2 Unit.
    OBJECTIVE People with neurofibromatosis Type 2 (NF2) have a genetic predisposition to nervous system tumors. NF2-associated schwannomas stabilize or decrease in size in over half of the patients while they are receiving bevacizumab. NF2 patients treated with bevacizumab for rapidly growing schwannoma were retrospectively reviewed with regard to ependymoma prevalence and response to treatment. Read More

    Causes and management of facial nerve palsy.
    Br J Hosp Med (Lond) 2016 Dec;77(12):686-691
    Consultant Ear, Nose and Throat Surgeon, Department of Otolaryngology, Queen Elizabeth Hospital, Birmingham B15 2TH.
    Facial nerve palsy causes disfigurement with cosmetic, functional and psychological repercussions. The facial nerve can be affected anywhere along its course. A comprehensive assessment considering all differential diagnoses is critical to optimal management, as prompt, appropriate therapy leads to better outcomes. Read More

    Acoustic neuroma as first sign of inner ear functional disorders.
    Otolaryngol Pol 2016 Oct;70(5):19-25
    Klinika Otolaryngologii, Onkologii Laryngologicznej, Audiologii i Foniatrii, II Katedra Otolaryngologii, Uniwersytet Medyczny w Łodzi Kierownik Katedry i Kliniki: prof. dr hab. n. med. Jurek Olszewski.
    Introduction: The aim of this work was to describe acoustic neuromas as the first signs of inner ear functional disorders.

    Material And Methods: The study covered 3,456 audiological and otoneurological patients, who were treated in the Department of Otolaryngology, Laryngological Oncology, Audiology and Phoniatrics Military Medical Academy University Teaching Hospital in Lodz within the period of 2011-2016. Among the studied subjects, an acoustic neuroma on the vestibulocochlear nerve was diagnosed in 13 cases (5,16%), including 9 women and 4 men. Read More

    Primary solitary intralabyrinthine schwannoma: A report of 7 cases and a review of the literature.
    Ear Nose Throat J 2016 Dec;95(12):481-491
    Unit of Otoneurology, Lin Medical Center, Rothschild Ave. 35, Haifa 3515209, Israel.
    Intralabyrinthine schwannomas (ILSs) are uncommon benign tumors that originate in the Schwann cell sheath of the intralabyrinthine distal branches of the vestibulocochlear nerve. They have no initial involvement in the internal auditory canal, although that might develop later. These lesions can arise inside the cochlea, originate in the vestibule or, in rare cases, develop in the semicircular canals. Read More

    Stereotactic radiotherapy of vestibular schwannoma : Hearing preservation, vestibular function, and local control following primary and salvage radiotherapy.
    Strahlenther Onkol 2017 Mar 7;193(3):200-212. Epub 2016 Dec 7.
    Department of Radiation Oncology, Friedrich-Alexander-University Erlangen-Nuremberg, Universitaetsstraße 27, 91054, Erlangen, Germany.
    Objective: The aim of this publication is to present long-term data on functional outcomes and tumor control in a cohort of 107 patients treated with stereotactic radiotherapy (RT) for vestibular schwannoma.

    Patients And Methods: Included were 107 patients with vestibular schwannoma (primary or recurrent following resection) treated with stereotactic RT (either fractioned or single-dose radiosurgery) between October 2002 and December 2013. Local control and functional outcomes were determined. Read More

    A case of infected schwannoma mimicking malignant tumor.
    World J Surg Oncol 2016 Dec 7;14(1):302. Epub 2016 Dec 7.
    Department of Orthopaedic Surgery, Kanazawa University School of Medicine, 13-1 Takara-machi, Kanazawa, Ishikawa, 920-8640, Japan.
    Background: Infected schwannoma has been reported, this being one of the four cases published in the literature. Infected schwannoma has proven to be a tough diagnostic challenge to the treating tumor surgeon, mimicking infectious entities and most essentially, a malignant tumor.

    Case Presentation: The authors report the case of a 64-year-old male with a soft tissue mass in his right gluteal area that presented initially with right leg pain, then later with signs of inflammation on the tumor area. Read More

    Surgical management of primary parapharyngeal space tumors: a 10-year review.
    Acta Otolaryngol 2017 Jun 6;137(6):656-661. Epub 2016 Dec 6.
    a Department of Otorhinolaryngology-Head and Neck Surgery , Fudan University Affiliated Eye, Ear, Nose and Throat Hospital , Shanghai , PR China.
    Conclusions: Most neoplasms of the parapharyngeal space are benign. The transcervical surgical approach is the preferred procedure in most cases. Intra-operative endoscopic exploration offers a new surgical management technique to reduce operative complications and post-operative recurrence rates. Read More

    Incidental findings on magnetic resonance imaging of the internal auditory meatus performed to investigate audiovestibular symptoms.
    J Laryngol Otol 2017 Jan 5;131(1):32-36. Epub 2016 Dec 5.
    Department of Otolaryngology,Blackpool Victoria Hospital,UK.
    Objective: To determine the frequency of incidental findings found on magnetic resonance imaging scans of the internal auditory meatus performed to investigate audiovestibular symptoms, and to determine how to best manage these when found.

    Method: A retrospective review was conducted of internal auditory meatus magnetic resonance imaging scans during a three-month period in the radiology department at a UK district general hospital.

    Results: A total of 109 scans were reviewed. Read More

    Primary hepatic malignant peripheral nerve sheath tumor successfully treated with combination therapy: a case report and literature review.
    Ann Surg Treat Res 2016 Dec 25;91(6):327-331. Epub 2016 Nov 25.
    Department of Surgery, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.
    Primary malignant peripheral nerve sheath tumor (MPNST) in a young female patient, not associated with neurofibromatosis type-I is extremely rare in the liver. A 33-year-old female was admitted with a right flank pain for a weak. The CT scan showed 12. Read More

    Results of hemihypoglossal-facial nerve anastomosis in the treatment of facial nerve paralysis after failed stereotactic radiosurgery for vestibular schwannoma.
    J Neurosurg Sci 2017 04;61(2):207-212
    Department of Neurosurgery, Medical University of Warsaw, Warsaw, Poland -
    Vestibular schwannoma treatment with stereotactic radiosurgery (SRS) carries a risk of facial nerve (CNVII) palsy that is lower than that with microneurosurgery. The results of hemihypoglossal-facial nerve anastomosis (HHFA) have not been described yet in CNVII palsy after failed stereotactic radiosurgery (SRS). Here we report a case series of the first four consecutive patients (three women; average age 58. Read More

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