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    Solid-Cystic Hypoglossal Nerve Schwannoma with Fluid-Fluid Level: A Rare Case Report.
    J Clin Diagn Res 2016 Dec 1;10(12):TD06-TD08. Epub 2016 Dec 1.
    Resident, Department of Radiology, Krishna Hospital and Medical Research Center , Karad, Maharashtra, India .
    Schwannomas (neurinoma, neurilemmoma) are benign slow-growing encapsulated tumours originating from well-differentiated myelin-producing Schwann cells or nerve fiber sheet cells at the glial-Schwann cell junction. Hypoglossal nerve schwannoma mostly develops in the intracranial and extra-cranial segment or in both intracranial and extra-cranial segment forming a dumbbell shape tumour. The peripheral hypoglossal schwannomas are very rare. Read More

    Schwannoma of the tongue-A common tumour in a rare location: A case report.
    Eur J Radiol Open 2017 1;4:1-3. Epub 2017 Feb 1.
    Serviço de Imagem Médica - Centro Hospitalar Universitário de Coimbra, Praceta Mota Pinto, 3000-075 Coimbra, Portugal.
    Schwannoma is a benign tumour that arises from Schwann cells of the peripheral nerve sheath, and is a common tumour of the head and neck. However, intraoral location is very uncommon (only 1% of all head and neck schwannomas). We report a rare case of lingual schwannoma in a 20-year-old male patient who presented with a small, slow-growing mass over the right lateral border of the tongue with 1 year of evolution and that became recently ulcerated. Read More

    Inter-observer variability between radiologists reporting on cerebellopontine angle tumours on magnetic resonance imaging.
    J Laryngol Otol 2017 Jan;131(S1):S47-S49
    Department of Otolaryngology,St Vincent's Private Hospital,Sydney,Australia.
    Background: Studies demonstrate the significance of intra- and inter-observer variability when measuring cerebellopontine angle tumours on magnetic resonance imaging, with measured differences as high as 2 mm.

    Objective: To determine intra- and inter-observer measurement variability of cerebellopontine angle tumours in a specialised institution.

    Methods: The magnetic resonance imaging maximal diameter of 12 randomly selected cerebellopontine angle tumours were independently measured by 4 neuroradiologists at a tertiary referral centre using a standard definition for maximal tumour diameter. Read More

    Epithelioid schwannoma of the skin displaying unique histopathological features: a teaching case giving rise to diagnostic difficulties on a morphological examination of a resected specimen, with a brief literature review.
    Diagn Pathol 2017 Jan 19;12(1):11. Epub 2017 Jan 19.
    Department of Pathology, Field of Oncology, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima, 890-8544, Japan.
    Background: Epithelioid schwannoma as a rare variant poses a challenge to all pathologists, as this uncommon entity is extremely difficult to conclusively diagnose by morphological analyses on a resected sample alone owing to its unique histopathological features. However, few papers have described the detailed clinicopathological characteristics of epithelioid schwannoma.

    Case Presentation: A 65-year-old female presented with a history of a flat and slightly elevated firm and tan plaque accompanied by occasional tenderness, measuring 10 × 8 mm, in the right joint of her hand 1 year before resection. Read More

    [Schwannoma of the Upper Extremity: Retrospective Analysis of 17 Cases].
    Acta Med Port 2016 Sep 30;29(9):519-524. Epub 2016 Sep 30.
    Serviço de Cirurgia Plástica, Reconstrutiva e Maxilo-Facial. Hospital Egas Moniz. Centro Hospitalar de Lisboa Ocidental. Lisboa. Portugal.
    Introduction: Schwannoma or neurilemmoma is a benign peripheric nerve tumor that usually presents as a slow growing single lesion; it has origin in Schwann cells proliferation. Although it represents a small percentage of the benign tumors of the upper arm, it is the most frequent of neural origin. We present a retrospective study of upper limb schwannomas; our aim is establish the appropriate preoperative approach, to recognise the efficiency of the treatment and the pos-operative follow-up. Read More

    Vertigo Perception and Quality of Life in Patients after Surgical Treatment of Vestibular Schwannoma with Pretreatment Prehabituation by Chemical Vestibular Ablation.
    Biomed Res Int 2016 8;2016:6767216. Epub 2016 Dec 8.
    Department of Neurology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Postgraduate Medical School, Prague, Czech Republic.
    Surgical removal of vestibular schwannoma causes acute vestibular symptoms, including postoperative vertigo and oscillopsia due to nystagmus. In general, the dominant symptom postoperatively is vertigo. Preoperative chemical vestibular ablation can reduce vestibular symptoms postoperatively. Read More

    Outcomes of Treatment for Malignant Peripheral Nerve Sheath Tumors: Different Clinical Features Associated with Neurofibromatosis Type 1.
    Cancer Res Treat 2016 Dec 1. Epub 2016 Dec 1.
    Division of Pediatric Hemato-oncology, Department of Pediatrics, Yonsei University College of Medicine, Yonsei University Health System, Seoul, Korea.
    Purpose: Malignant peripheral nerve sheath tumors (MPNSTs) are a rare subtype of sarcoma that occur spontaneously or in association with neurofibromatosis type 1 (NF-1). This study aimed to clinically differentiate these types of MPNSTs.

    Materials And Methods: The study reviewed 95 patients diagnosed with and treated for MPNST at Yonsei University Health System, Seoul, Korea over a 27-year period. Read More

    [Maxillary trigeminal schwannoma. Presentation of a case and review of literature].
    Cir Cir 2016 Dec 30. Epub 2016 Dec 30.
    Servicio de Neurocirugía, Hospital General Balbuena, Ciudad de México, México.
    Introduction: Schwannomas are benign tumours that are relatively common in the head, however the involvement of the sinunasal region is rare and there are only 5 cases reported in the maxilla in current literature, representing less than 1% of bone tumours.

    Clinical Case: We report the case of a woman with a right maxillary schwannoma who underwent a complete resection of the lesion. Emphasis is placed on the rarity of the lesion in terms of its location and includes a review of clinical behaviour, diagnosis and current treatment options. Read More

    Tumor Occupation in the Spinal Canal and Clinical Symptoms of Cauda Equina Schwannoma: An Analysis of 22 Cases.
    Asian Spine J 2016 Dec 8;10(6):1079-1084. Epub 2016 Dec 8.
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
    Study Design: Retrospective, radiological study.

    Purpose: To determine the relationship between clinical symptoms and the extent of tumor occupation of the spinal canal by cauda equina schwannoma.

    Overview Of Literature: Little is known about the relationship between the size of tumors of the cauda equina and the manifestation of clinical symptoms. Read More

    Surgical management of primary parapharyngeal space tumors: a 10-year review.
    Acta Otolaryngol 2016 Dec 6:1-6. Epub 2016 Dec 6.
    a Department of Otorhinolaryngology-Head and Neck Surgery , Fudan University Affiliated Eye, Ear, Nose and Throat Hospital , Shanghai , PR China.
    Conclusions: Most neoplasms of the parapharyngeal space are benign. The transcervical surgical approach is the preferred procedure in most cases. Intra-operative endoscopic exploration offers a new surgical management technique to reduce operative complications and post-operative recurrence rates. Read More

    Incidental findings on magnetic resonance imaging of the internal auditory meatus performed to investigate audiovestibular symptoms.
    J Laryngol Otol 2017 Jan 5;131(1):32-36. Epub 2016 Dec 5.
    Department of Otolaryngology,Blackpool Victoria Hospital,UK.
    Objective: To determine the frequency of incidental findings found on magnetic resonance imaging scans of the internal auditory meatus performed to investigate audiovestibular symptoms, and to determine how to best manage these when found.

    Method: A retrospective review was conducted of internal auditory meatus magnetic resonance imaging scans during a three-month period in the radiology department at a UK district general hospital.

    Results: A total of 109 scans were reviewed. Read More

    Primary hepatic malignant peripheral nerve sheath tumor successfully treated with combination therapy: a case report and literature review.
    Ann Surg Treat Res 2016 Dec 25;91(6):327-331. Epub 2016 Nov 25.
    Department of Surgery, Soonchunhyang University Cheonan Hospital, Cheonan, Korea.
    Primary malignant peripheral nerve sheath tumor (MPNST) in a young female patient, not associated with neurofibromatosis type-I is extremely rare in the liver. A 33-year-old female was admitted with a right flank pain for a weak. The CT scan showed 12. Read More

    Single-Stage Operation for Giant Schwannoma at the Craniocervical Junction with Minimal Laminectomy: A Case Report and Literature Review.
    Korean J Spine 2016 Sep 30;13(3):173-175. Epub 2016 Sep 30.
    Department of Neurosurgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.; Department of Neurosurgery, Kangwon National University Hospital, Chuncheon, Korea.
    Here we report a single-stage operation we performed on a patient with a large schwannoma that extended from the lower clivus to the cervico-thoracic junction caudally. A number of authors have previously performed multilevel laminectomy to remove giant schwannomas that extend for considerable length. This technique has caused cervical instability such as kyphosis or gooseneck deformity on several occasions. Read More

    Improved patient quality of life following intradural extramedullary spinal tumor resection.
    J Neurosurg Spine 2016 Nov 24;25(5):640-645. Epub 2016 Jun 24.
    Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, Pennsylvania.
    OBJECTIVE Resection significantly improves the clinical symptoms and functional outcomes of patients with intradural extramedullary tumors. However, patient quality of life following resection has not been adequately investigated. The aim in this retrospective analysis of prospectively collected quality of life outcomes is to analyze the efficacy of resection of intradural extramedullary spinal tumors in terms of quality of life markers. Read More

    Transischiorectal fossa approach for resection of pudendal nerve schwannoma: case report.
    J Neurosurg Spine 2016 Nov 17;25(5):636-639. Epub 2016 Jun 17.
    Department of Neurological Surgery and the Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, Florida.
    Pudendal nerve schwannomas are very rare, with only two cases reported in the English-language literature. The surgical approaches described in these two case reports are the transgluteal approach and the laparoscopic approach. The authors present the case of a patient with progressive pelvic pain radiating ipsilaterally into her groin, vagina, and rectum, who was subsequently found to have a pudendal schwannoma. Read More

    Novel dural incision and closure procedure for preventing postoperative cerebrospinal fluid leakage during the surgical removal of dumbbell-shaped spinal tumors: technical note.
    J Neurosurg Spine 2016 Nov 10;25(5):620-625. Epub 2016 Jun 10.
    Department of Neurosurgery, Shinshu University School of Medicine, Matsumoto, Japan.
    The authors report on a new method for removing dumbbell-shaped spinal tumors that avoids the risk of postoperative cerebrospinal fluid (CSF) leakage. Adequate visualization of the intra- and extradural components of the tumor is achieved with the use of separate dural incisions. First, the dura mater is opened along the dural theca to provide adequate visualization of the intradural portion of the mass; then, a second incision is made along the nerve root to remove the extradural component. Read More

    Vestibular schwannomas treated with Cyberknife®: clinical outcomes.
    Tumori 2016 Dec 22;102(6):569-573. Epub 2016 Sep 22.
    Department of Radiotherapy, Institut de Cancérologie de Lorraine, Vandoeuvre-les-Nancy - France.
    Purpose: Fractionated stereotactic radiotherapy (FSR) is a recognized treatment for vestibular schwannomas (VS). This study's aim is to present clinical outcomes and local control (LC) results for patients with VS treated with FSR using the Cyberknife® (CK) in 2 French cancer centers.

    Methods: Patients treated with FSR for VS between 2007 and 2012 were retrospectively analyzed. Read More

    Audiovestibular Function Deficits in Vestibular Schwannoma.
    Biomed Res Int 2016 22;2016:4980562. Epub 2016 Sep 22.
    Department of Otorhinolaryngology and Head and Neck Surgery, Grosshadern Medical Center, University of Munich, Marchioninistr. 15, 81377 Munich, Germany.
    Introduction. Vestibular schwannomas (VS) are benign tumours of the vestibular nerve and can lead to hearing loss, tinnitus, vertigo, facial palsy, and brainstem compression. Audiovestibular diagnostic tests are essential for detection and treatment planning. Read More

    Schwannoma of the Median Nerve at Mid Forearm Level.
    J Orthop Case Rep 2016 Apr-Jun;6(2):66-68
    Department of Orthopaedics, S.M.S. Medical College, Jaipur(Rajasthan). India.
    Introduction: Schwannomas are also known as neurilemmoma that usually originate from Schwann cells located in the peripheral nerve sheaths. It usually occurs in the age group of 20 to 70 years. These are the commonest tumors of the peripheral nerves, 5% of which occur in the adults and 19% of the tumors occur in upper extremities. Read More

    Gastric plexiform schwannoma in association with neurofibromatosis type 2.
    Clin J Gastroenterol 2016 Dec 30;9(6):352-357. Epub 2016 Sep 30.
    Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA.
    Plexiform schwannoma (PS) is an uncommon variant of schwannoma characterized by a multinodular (plexiform) growth pattern. It comprises up to 5 % of all schwannomas. The association between PS and neurofibromatosis type 1 or type 2 (NF1/NF2) is only rarely reported. Read More

    Magnetic Resonance Imaging Features of Intramedullary Schwannomas.
    J Comput Assist Tomogr 2017 Jan;41(1):137-140
    From the Huashan Hospital of Fudan University, Shanghai, China.
    Objective: To identify the magnetic resonance imaging features of intramedullary spinal schwannomas.

    Methods: Clinical and magnetic resonance imaging findings of 8 patients with pathologically confirmed intramedullary schwannomas were reviewed.

    Results: There were 6 male and 2 female patients (mean age, 49 years). Read More

    Clinical, Morphologic, and Pathologic Features Associated With Increased FDG Uptake in Schwannoma.
    AJR Am J Roentgenol 2016 Dec 22;207(6):1288-1296. Epub 2016 Sep 22.
    1 Department of Diagnostic Imaging and Nuclear Medicine, Kyoto University Hospital, 54 Shogoin-Kawaharacho, Sakyo-ku, Kyoto, 606-8507, Japan.
    Objective: The objective of this study was to investigate the clinical, morphologic, and pathologic features associated with increased (18)F-FDG uptake in benign schwannomas.

    Materials And Methods: Twenty-two schwannomas in 22 patients (age range, 25-81 years) who had FDG PET or PET/CT scans and subsequently underwent surgical re-section were retrospectively analyzed. The maximum standardized uptake value (SUVmax) was compared with patient age, sex, tumor location (gastrointestinal vs nongastrointestinal origin), tumor size, gross appearance, intratumoral cellularity, intratumoral infiltration of inflammatory cells, presence of peritumoral lymphoid cuffs, and expression status of glucose transporters 1 and 3 on tumor cells. Read More

    Neurophysiological intraoperative monitoring during an optic nerve schwannoma removal.
    J Clin Monit Comput 2016 Sep 1. Epub 2016 Sep 1.
    Neurosurgery Department, National Institute of Neurology and Neurosurgery, Mexico City, Mexico.
    This paper reports the case of a patient with optic nerve schwannoma and the first use of neurophysiological intraoperative monitoring of visual evoked potentials during the removal of such tumor with no postoperative visual damage. Schwannomas are benign neoplasms of the peripheral nervous system arising from the neural crest-derived Schwann cells, these tumors are rarely located in the optic nerve and the treatment consists on surgical removal leading to high risk of damage to the visual pathway. Case report of a thirty-year-old woman with an optic nerve schwannoma. Read More

    Giant solitary ancient schwannoma of the pleura masquerading as bronchopneumonia.
    Lung India 2016 Jul-Aug;33(4):447-8
    Department of Pathology, Kovai Medical Center and Hospital, Coimbatore, Tamil Nadu, India.
    We report a 53-year-old female who presented with complaints of sudden onset breathlessness, cough with expectoration for 6 months, and a right lung base lesion in the chest X-ray, which was diagnosed and treated as bronchopneumonia by the family physician. High-resolution computed tomography of the chest was done which revealed a large heterogeneously enhancing mass in the right thoracic cavity. She underwent thoracotomy and was found to have a giant encapsulated and well-circumscribed mass arising from the pleura. Read More

    Orbital peripheral nerve sheath tumors.
    Surv Ophthalmol 2017 Jan - Feb;62(1):43-57. Epub 2016 Aug 26.
    Department of Ophthalmology, University of Washington, Seattle, Washington, USA.
    Peripheral nerve sheath tumors of the orbit and ocular adnexa are a rare group of neoplasms hallmarked by nonspecific clinical presentations, variable tumor locations, challenging therapeutic efforts, and occasional diagnostic dilemmas. We review these tumor types and provide an updated summary on their clinical, histopathologic, radiological, and emerging molecular features. Read More

    A Diagnostic Dilemma: Multiple Primary Intracranial Tumors Without Vestibular Schwannomas.
    Ann Otol Rhinol Laryngol 2016 Nov 23;125(11):938-942. Epub 2016 Aug 23.
    University of Arizona College of Medicine, Department of Otolaryngology, Tucson, Arizona, USA.
    Sinonasal schwannomas with intracranial extension are exceedingly rare, with only 7 cases reported in the literature. Schwannomas can be isolated or multiple and are commonly associated with familial disorders such as neurofibromatosis 2 (NF 2) or familial schwannomatosis or in sporadic cases seen in sporadic schwannomatosis. Nearly all people with NF2 older than 30 years of age will have the hallmark of bilateral vestibular schwannomas (VS). Read More

    Multiple schwannomas synchronously occurring in the porta hepatis, liver, and gallbladder: first case report.
    Medicine (Baltimore) 2016 Aug;95(33):e4378
    aDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery bKey Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health cKey Laboratory of Organ Transplantation dCollaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases eDepartment of pathology (KS), First Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Province, Hangzhou,China.
    Background: Schwannomas are mesenchymal neoplasms that arise from Schwann cells with low malignant potential. Schwannomas originating from the porta hepatis or intra-abdominal organs are extremely rare. To our knowledge, multiple schwannomas synchronously occurring in the porta hepatis, liver, and gallbladder have not been reported so far and we first report one in the present case. Read More

    Prognostic factors affecting the surgical outcome of anterolateral benign tumors in the foramen magnum region.
    Int J Surg 2016 Sep 12;33 Pt A:172-6. Epub 2016 Aug 12.
    Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, China. Electronic address:
    Introduction: Anterior and anterolateral tumors in foramen magnum region are rare and surgically challenging although most of them are benign. The optimal approach is debatable and prognostic factors affecting surgical outcome remains unclear. We aimed to identify factors including surgical approach determining postoperative outcome. Read More

    Clinical Outcomes of Intracranial Nonvestibular Schwannomas Treated with LinacBased Stereotactic Radiosurgery and Radiotherapy.
    Asian Pac J Cancer Prev 2016 ;17(7):3271-6
    Radiation and Oncology Unit, Department of Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand Email :
    Background: Intracranial nonvestibular schwannomas arising from various cranial nerves excluding CN VIII are uncommon. Recently, stereotactic radiosurgery (SRS) and fractionated stereotactic radiotherapy (SRT) have been widely reported as effective treatment modalities for nonvestibular schwannomas. The purpose of this study was to study the long term clinical outcome for nonvestibular schwannomas treated with both XKnife and CyberKnife (CK) radiosurgery at one institution. Read More

    [Evaluation of short-term surgical outcomes in facial paralysis patients treated by trigeminal neurotization].
    Zh Vopr Neirokhir Im N N Burdenko 2016;80(4):31-9
    Federal Neurosurgical Center, Novosibirsk, Russia; Novosibirsk State University, Novosibirsk, Russia.
    Unlabelled: The management of patients with facial nerve palsy is a challenge of modern neurosurgery. The study purpose was to evaluate the degree of facial nerve function recovery, following trigeminal neurotization. Trigeminal neurotization was performed in 23 patients within 1 to 10 months after the development of facial paralysis. Read More

    Recurrent Ancient Intraosseous Neurilemmoma of Maxilla: A Rare Case Report.
    Iran J Pathol 2016 ;11(2):176-80
    Dept. of Oral & Maxillofacial Pathology and Microbiology Dr D Y Patil Dental College & Hospital, Sector 7, Nerul, Navi Mumbai, Maharashtra, India.
    Neurilemmomas are benign tumors of peripheral nerve sheath Schwann cells. One of the variants of neurilemmoma is the ancient type of neurilemmoma characterized by degenerative features such as cystic degeneration, calcification, hemorrhage and hyalinization which could be easily misdiagnosed. Their occurrence in oral cavity is extremely rare and intraosseous type occurring in maxilla is exceedingly rare with very few cases being published in literature. Read More

    Pineal region schwannoma arising from the trochlear nerve.
    J Clin Neurosci 2016 Oct 3;32:159-61. Epub 2016 Aug 3.
    University of Miami Miller School of Medicine, Department of Neurological Surgery, Lois Pope Life Center, 1095 NW 14th Terrace (D4-6), Miami, FL 33136, USA. Electronic address:
    Schwannomas arising from the trochlear nerve are very rare and to our knowledge, less than 35 histologically documented cases have been reported in the literature. There are no reports of a schwannoma in the pineal region. We report a 24-year-old woman who underwent a para-occipital trans-tentorial approach and gross total excision of a pineal region schwannoma arising from the trochlear nerve. Read More

    Palliative Epineurotomy for Focal Radial Malignant Peripheral Nerve Sheath Tumor in a Dog.
    J Am Anim Hosp Assoc 2016 Sep-Oct;52(5):330-4. Epub 2016 Aug 3.
    From the Royal Veterinary College, Hatfield, Hertfordshire, United Kingdom.
    This case report describes the diagnosis of a peripheral nerve sheath tumor of the deep branch of the radial nerve distal to the elbow in a dog. The lesion was identified using computed tomography and ultrasonography and confirmed as sarcoma on histopathological analysis of incisional biopsies. Clinical signs dramatically improved following surgical biopsy before recurring three months later. Read More

    Hemorrhagic, calcified, and ossified benign retroperitoneal schwannoma: First case report.
    Medicine (Baltimore) 2016 Jul;95(30):e4318
    aDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery bKey Laboratory of Combined Multi-organ Transplantation, Ministry of Public Health cKey Laboratory of Organ Transplantation dCollaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases eDepartment of pathology, First Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Province, Hangzhou,China.
    Background: Schwannomas are mesenchymal tumors arising from the neural sheaths of peripheral nerves. They can almost develop in any part of the body, while head, neck and extremities are the most common sites. Occurrence in the retroperitoneum is rare. Read More

    A giant ancient schwannoma mimicking an adnexal mass: Case report.
    Medicine (Baltimore) 2016 Jul;95(30):e4240
    aDepartment of Surgical Oncology, Suleyman Demirel University Faculty of Medicine, Isparta bDepartment of General Surgery cDepartment of Pathology, Medical Faculty, Trakya University, Edirne dDepartment of General Surgery, Mengücek Gazi Education and Research Hospital, Erzincan, Turkey.
    Introduction: Ancient schwannoma is a rare tumor of the peripheral nerve sheath. As degenerative properties are defined histologically, it can be wrongly interpreted as malignant.

    Case Presentation: The case presented here is of a giant ancient schwannoma with a pelvic retroperitoneal location, which was mimicking an adnexal mass. Read More

    Two cases of cystic enlargement of vestibular schwannoma as a late complication following gamma knife surgery.
    J Clin Neurosci 2016 Nov 25;33:239-241. Epub 2016 Jul 25.
    Department of Neurosurgery, Yokohama Rosai Hospital, 3211 Kozukue-cho, Kouhoku-ku, Yokohama, Kanagawa 222-0036, Japan.
    Cyst formation is the most common long-term complication after gamma knife surgery (GKS) for cerebral arteriovenous malformations; however, this rarely occurs after GKS for vestibular schwannoma (VS). We describe two patients that developed aggressive, symptomatic large cysts at more than 4 and 12years after GKS for VS, although the tumor control for these patients had been acceptable at 3 and 11years, respectively. During the surgery, a reddish lesion, which was distinct from the surrounding tumor, was observed. Read More

    Pitfalls and uncertain prognosis in pathological diagnosis of psammomatous melanotic schwannoma.
    J Clin Neurosci 2016 Nov 25;33:236-239. Epub 2016 Jul 25.
    Department of Pathology and Laboratory Medicine, University of Toronto, 27 King's College Cir, Toronto, ON M5S 1A1, Canada; Li Ka Shing Knowledge Institute, Toronto, ON, Canada; Department of Laboratory Medicine, St. Michael's Hospital, Toronto, ON, Canada. Electronic address:
    A 20-year-old woman presenting with a pelvic mass identified as a psammomatous melanotic schwannoma (PMS) with atypical histological features was later found to have family history of cardiac myxomas consistent with Carney's complex. The BRAF V600E mutation was absent in the tumor. Read More

    Comparing the sensitivity of linear and volumetric MRI measurements to detect changes in the size of vestibular schwannomas in patients with neurofibromatosis type 2 on bevacizumab treatment.
    Br J Radiol 2016 Sep 25;89(1065):20160110. Epub 2016 Jul 25.
    3 Department of Neuroradiology, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
    Objective: To compare the sensitivity of linear and volumetric measurements on MRI in detecting schwannoma progression in patients with neurofibromatosis type 2 on bevacizumab treatment as well as the extent to which this depends on the size of the tumour.

    Methods: We compared retrospectively, changes in linear tumour dimensions at a range of thresholds to volumetric tumour measurements performed using Brainlab iPlan(®) software (Feldkirchen, Germany) and classified for tumour progression according to the Response Evaluation in Neurofibromatosis and Schwannomatosis (REiNS) criteria.

    Results: Assessment of 61 schwannomas in 46 patients with a median follow-up of 20 months (range 3-43 months) was performed. Read More

    Growth rate of vestibular schwannoma.
    J Clin Neurosci 2016 Oct 20;32:1-8. Epub 2016 Jul 20.
    Department of Surgery, The University of Melbourne, Parkville, Australia.
    Vestibular schwannoma (VS) is the most common tumor in the extra-axial posterior fossa compartment in adults. Growth rate is paramount to decision making regarding treatment and follow up of these tumors. We conducted a comprehensive review of the literature to answer four questions: What percentage of newly diagnosed VS will grow on follow-up? What factors correlate to tumor growth? What is the "normal" growth rate for sporadic VS? What factors characterize VS with rapid growth? Thirty-seven reports, with more than 4000 patients, fit our review criteria. Read More

    Intraventricular Neurilemmoma (Schwannoma): Shall GFAP Immunostaining Be Regarded as a Histogenetical Tag or as a Mere Histomimetical Trait?
    Case Rep Pathol 2016 30;2016:2494175. Epub 2016 Jun 30.
    Department of Neuropathology, National Institute of Neurology & Neurosurgery "Manuel Velasco Suárez", Tlalpan, 14269 Mexico City, DF, Mexico.
    Neurilemmomas are benign neoplasms presumedly derived from Schwann cells which rarely originate within the central nervous system. Moreover, their intraventricular location has been seldom noticed with less than 30 cases reported worldwide. Here, we add another case study to the record as well as the fifth one in Latin American population. Read More

    Histopathological and Radiographic Analysis of Dental Follicle of Impacted Teeth Using Modified Gallego's Stain.
    J Clin Diagn Res 2016 May 1;10(5):ZC106-11. Epub 2016 May 1.
    Professor and PG Guide, Department of Oral and Maxillofacial Pathology and Microbiology, Padmashree Dr D Y Patil Dental College and Hospital , Navi Mumbai, Maharashtra, India .
    Introduction: In the WHO classification of odontogenic tumours, hard tissue formation has been considered as a sub-classification however, this parameter has not been much explored in dental follicle in literature. Epithelial-mesenchymal interactions play an important role in odontogenesis and its associated pathologies; therefore research on dental follicle should also include mesenchymal components along with epithelial components. Additionally, special stains to identify the nature of such depositions in dental follicle have been less explored. Read More

    Hybrid open/closed resection procedure for ancient retroperitoneal Schwannoma: case report and review of the literature.
    Acta Chir Belg 2016 Oct 2;116(5):289-292. Epub 2016 Jun 2.
    b Department of General Surgery , AZ Sint-Maria Halle. Ziekenhuislaan , Halle , Belgium.
    Background: Retroperitoneal, ancient Schwannomas are rare tumors that arise from neural sheath Schwann cells. Due to their location and size, these benign tumors can become symptomatic and need surgery. Laparoscopic resection is rarely performed for retroperitoneal Schwannomas. Read More

    Schwannoma Showing Avid Uptake on 68Ga-PSMA-HBED-CC PET/CT.
    Clin Nucl Med 2016 Sep;41(9):703-4
    From the *Department of Nuclear Medicine, Royal North Shore Hospital; †The University of New South Wales, Sydney; ‡Genesis Cancer Care, Mater Hospital, North Sydney; §The University of Sydney; ∥Department of Nuclear Medicine, St Vincent's Hospital, Sydney, Australia.
    Ga prostate-specific membrane antigen (PSMA) PET/CT is a relatively new and highly sensitive imaging modality used in staging metastatic prostate cancer. We report a case of a 65-year-old man with newly diagnosed prostate carcinoma who had a PSMA PET/CT scan for staging of his disease. A PSMA-avid right pelvic mass was identified anterior to the sacrum. Read More

    Subdural fluid collection and hydrocephalus following cervical schwannoma resection: hydrocephalus resolution after spinal pseudomeningocele repair: case report.
    J Neurosurg Spine 2016 Dec 8;25(6):762-765. Epub 2016 Jul 8.
    Neurosurgical Department, Azienda Ospedaliero Universitaria Pisana, Pisa, Italy.
    The authors report the case of a 31-year-old man who developed neck pain and headache 2 months after the uncomplicated resection of a cervical schwannoma. MR imaging revealed infratentorial subdural fluid collections and obstructive hydrocephalus associated with cervical pseudomeningocele. The clinical symptoms, subdural fluid collections, and ventricular dilation resolved after surgical correction of the pseudomeningocele. Read More

    Robot-assisted laparoscopic resection of a huge pelvic tumor: A case report.
    Arch Ital Urol Androl 2016 Jul 4;88(2):144-6. Epub 2016 Jul 4.
    Department of Urology, Military General Hospital of Beijing PLA, Beijing.
    The traditional open surgery, for the treatment of huge tumor in the narrow space of pelvic cavity and in close proximity to pelvic organs and neurovascular structures, is very difficult and challenging. We report a case of huge neurilemmoma operated using the robot-assisted laparoscopy. We used interventional pre-operation embolization to control blood supply of tumor because MRI showed the tumor had a sufficient blood supply. Read More

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