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    High-resolution ultrasonography and shear-wave sonoelastography of a cystic radial nerve Schwannoma.
    J Ultrasound 2017 Sep 6;20(3):261-266. Epub 2017 Jun 6.
    Department of Radiology, Logan University, 1851 Schoettler Road, Chesterfield, MO 63017 USA.
    Peripheral nerve tumors are often evaluated with magnetic resonance imaging (MRI), although there are many advantages offered with high-resolution ultrasonography (HRUS). This case report emphasizes the value of HRUS in the diagnosis and management of a patient with a cystic radial nerve Schwannoma. In addition, information on tumor stiffness, obtained with shear-wave sonoelastography (SWE), is presented. Read More

    Schwannoma of the hypoglossal nerve: Review of the literature based on an illustrative case.
    Mol Clin Oncol 2017 Aug 21;7(2):288-294. Epub 2017 Jun 21.
    Department of Surgery, IRCCS-Azienda Ospedaliera Universitaria San Martino-IST, University of Genoa, I-16132 Genoa, Italy.
    Schwannomas are benign tumours that originate from the myelin sheath of peripheral nerves. They are characterised by a slow growth tendency. Benign schwannomas represent 35% of the head and neck district tumours. Read More

    Oddities Sporadic Neurofibroma of the Urinary Bladder. A Case Report.
    Urol Case Rep 2017 Sep 12;14:42-44. Epub 2017 Jul 12.
    Department of Urology, Bicêtre Hospital, Le Kremlin Bicêtre, France.
    Neurofibromas of the urinary bladder are an exceedingly rare entity and are considered mostly in conjunction with the disease of neurofibromatosis type 1. The fortuitous discovery of vesical plexiform neurofibromas without other stigmata of the disease is presented in a 57-year-old male patient. The course of his condition, modalities of investigation and a non-precedent treatment plan are demonstrated. Read More

    Schwannoma of the tongue: a case report with review of literature.
    Maxillofac Plast Reconstr Surg 2017 Dec 5;39(1):17. Epub 2017 Jul 5.
    Department of Oral and Maxillofacial Surgery, College of Medicine and Medical Research Institute, Chungbuk National University, SeoWon-gu Chungdae-ro 1, Cheong-ju, 28644 South Korea.
    Background: Schwannomas (or neurilemmomas) of the tongue are benign, usually solitary, encapsulated masses derived from Schwann cells. Clinical evidence indicates that schwannoma is painless and slow growing. In general, schwannoma is treated by surgical excision. Read More

    [Evaluation of a new closure technique of large defects after endoscopic full-thickness resection].
    Zhonghua Wei Chang Wai Ke Za Zhi 2017 Jul;20(7):775-781
    Department of Endoscopy, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
    Objective: To investigate the security and efficacy of a new endoscopic closure method of large defects after endoscopic full-thickness resection (EFTR) double purse-string suture using two endoloops and metallic clips via single-channel endoscopy.

    Methods: Clinical data of 23 cases with submucosal tumors (SMT) who received endoscopic resection from June 2015 to July 2016 in our National Cancer Center were collected. For gastric and esophageal SMTs or the mucosa layer injured during submucosal tunneling endoscopic resection (STER), double purse-string suture was conducted after EFTR. Read More

    Giant Solitary Schwannoma of Submandibular Salivary Gland-A Rare Entity.
    J Maxillofac Oral Surg 2017 Sep 10;16(3):382-386. Epub 2016 Dec 10.
    Subharti Dental College, Swami Vivekanand Subharti University, NH - 58, Meerut, Uttar Pradesh 250005 India.
    Submandibular gland tumours, especially mesenchymal tumours, are extremely rare. Schwannoma of the salivary gland is a particularly rare form of an extracranial neurogenic tumor, of which ancient schwannoma is one of five variants. Since the first description, only a few ancient schwannomas have been reported in different locations in the head and neck region. Read More

    A Rare Report of Two Cases: Ancient Schwannoma of Infratemporal Fossa and Verocay Schwannoma of Buccal Mucosa.
    Ann Maxillofac Surg 2017 Jan-Jun;7(1):140-142
    Department of Oral Medicine and Radiology, Maulana Azad Institute of Dental Sciences, New Delhi, India.
    Schwannoma is a benign tumor that originates from Schwann cells of the peripheral nerve. Occurring as a common tumor in the head and neck region, its intraoral presentation is rare which accounts for only 1%. They are solitary, slow-growing, smooth-surfaced, usually asymptomatic, and encapsulated tumor. Read More

    Surgical management of a large neurilemmoma-like leiomyoma of the uterine cervix mimicking a retroperitoneal tumor.
    Gynecol Oncol Rep 2017 Aug 24;21:53-56. Epub 2017 Jun 24.
    Department of Pathologic Oncology, National Cancer Institute of Colombia (INC), Street 1 # 9-85, Bogotá, Colombia.
    •A large cervical neurilemmoma-like leiomyoma can simulate a retroperitoneal tumor.•They are extremely rare tumors that require adequate bleeding control.•Comprehensive anatomo-pathological study should be done to rule out malignancy. Read More

    Ancient schwannoma of the cervical sympathetic chain.
    Clin Case Rep 2017 Jul 16;5(7):1077-1080. Epub 2017 May 16.
    Brighton & Sussex University Hospitals NHS Trust177 Preston RdBrightonBN1 6AGUK.
    Ancient schwannomas exhibit characteristic histological features. Fine-needle aspiration cytology (FNAC) is of limited use. Radiological evidence demonstrating displacement of blood vessels may aid diagnosis of schwannoma. Read More

    [Anterior skull-base schwannoma].
    Neurocirugia (Astur) 2017 Jun 24. Epub 2017 Jun 24.
    Departamento de Anatomía Patológica, Hospital México, Costa Rica; Programa de Investigación Neurocirugía y Órganos de los Sentidos (PINECOS), Universidad de Costa Rica, San José, Costa Rica.
    Schwannomas are nerve sheath tumours that originate in Schwann cells. They are usually solitary and sporadic and manifest on peripheral, spinal or cranial nerves. Intracranial schwannomas tend to manifest on the eighth cranial nerve, particularly in patients with neurofibromatosis type2. Read More

    [Application value of whole brain 3D artery spin labeling in diagnosis of intracranial tumors].
    Zhonghua Yi Xue Za Zhi 2017 Jun;97(23):1801-1804
    State Key Laboratory of Oncology in Southern China, Minimally Invasive and Interventional Department, Sun Yat-sen University Cancer Center, Guangzhou 510060, China.
    Objective: To investigate the perfusion characteristics of arterial spin labeling (ASL) in intracranial tumor and its application value in classification. Methods: The clinical, pathological and imaging data of 44 patients with gliomas confirmed by pathology were analyzed retrospectively, including 9 low grade gliomas, 15 high grade gliomas, 11 cases of meningiomas, 6 cases of neurilemmoma, 3 cases of metastatic tumors.Conventional plain scan, 3D- ASL and MRI dynamic enhanced imaging (DSC-MRI) were performed. Read More

    Role of endoscopic ultrasound and endoscopic resection for the treatment of gastric schwannoma.
    Medicine (Baltimore) 2017 Jun;96(25):e7175
    Endoscopy Center, Shengjing Hospital of China Medical University, Shenyang, China.
    Endoscopic ultrasound (EUS) and endoscopic resection play an important role in gastric submucosal tumor. However, there were few articles regarding EUS and endoscopic resection of gastric schwannomas. Our aim was to evaluate the role of EUS and endoscopic resection in treating gastric schwannomas. Read More

    An Unusual Differential Diagnosis of Orbital Cavernous Hemangioma: Ancient Schwannoma.
    Case Rep Ophthalmol 2017 May-Aug;8(2):294-300. Epub 2017 May 8.
    Orbit and Oculoplastic Surgery Unit, Ophthalmology Department, Hospital Universitario Rámon y Cajal, IRYCIS, Oculoplastic Surgery Unit, Novovision, Madrid, Spain.
    Schwannomas are rare lesions of the orbit that can be confused with cavernous hemangioma on imaging studies. We report the case of an 84-year-old woman with a 9-year history of a tumoral lesion in the inferolateral left orbit. The imaging studies did not reveal specific characteristics, only bone remodeling due to the long evolution of the tumor. Read More

    Association of posterior semicircular canal hypofunction on video-head-impulse testing with other vestibulo-cochlear deficits.
    Clin Neurophysiol 2017 Aug 17;128(8):1532-1541. Epub 2017 May 17.
    Department of Neurology, University Hospital Zurich and University of Zurich, Zurich, Switzerland; Department of Ophthalmology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
    Objectives: The video-head-impulse test (vHIT) provides a functional assessment of all six semicircular canals (SCC). Occasionally isolated loss of the posterior canal(s) (ILPC) is diagnosed, though this finding is poorly characterized. Here we assessed how accurate that diagnosis is by measuring the co-occurrence of abnormalities on caloric irrigation, vestibular-evoked myogenic-potentials and audiometry. Read More

    Intraoral ancient schwannoma: A systematic review of the case reports.
    Dent Res J (Isfahan) 2017 Mar-Apr;14(2):87-96
    Nanotechnology Research Center, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran.
    Intraoral ancient schwannoma is a rare type of oral schwannoma, which is encapsulated and well demarcated from the surrounding tissues. Ancient schwannomas are associated with conventional features of neurilemmoma; however, they are distinguished from other types of schwannoma due to factors such as the long history, cellular architecture showing hypocellularity, and hyalinized matrices. This systematic review was performed through searching in databases such as PubMed and Google Scholar using related keywords (intraoral, oral, ancient, schwannoma, and neurilemmoma). Read More

    The Hippo signaling functions through the Notch signaling to regulate intrahepatic bile duct development in mammals.
    Lab Invest 2017 Jul 5;97(7):843-853. Epub 2017 Jun 5.
    Department of Medicine, Texas A&M Health Science Center, College of Medicine, Temple, TX, USA.
    The Hippo signaling pathway and the Notch signaling pathway are evolutionary conserved signaling cascades that have important roles in embryonic development of many organs. In murine liver, disruption of either pathway impairs intrahepatic bile duct development. Recent studies suggested that the Notch signaling receptor Notch2 is a direct transcriptional target of the Hippo signaling pathway effector YAP, and the Notch signaling is a major mediator of the Hippo signaling in maintaining biliary cell characteristics in adult mice. Read More

    Large schwannoma of the femur - a common tumor at an unusual site: a case report and review of the literature.
    J Med Case Rep 2017 May 31;11(1):147. Epub 2017 May 31.
    Nawaloka Hospitals PLC, Colombo, Sri Lanka.
    Background: Schwannomas are benign nerve sheath tumors and are most frequently encountered as soft tissue tumors of peripheral nerves of the head and neck or the extensor extremities. Osseous involvement is very uncommon with fewer than 200 cases described in the world literature, the majority of which arise in the skull (including mandible), vertebrae, and sacrum. Long bone involvement is highly unusual and of the approximately 20 cases described thus far, only five have been documented to arise in the femur. Read More

    Gamma Knife Radiosurgery for Vestibular Schwannomas and Quality of Life Evaluation.
    Stereotact Funct Neurosurg 2017 23;95(3):166-173. Epub 2017 May 23.
    Leksell Center for Radiosurgery and Brain Mapping, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
    Background: Further investigation is needed to look at the impact of vestibular schwannoma (VS) on the health-related quality of life (QOL) of participants who undergo Gamma Knife® radiosurgery (GKRS).

    Objectives: Investigators compared the QOL for VS participants to reported US population norms in order to evaluate disease burden and long-term QOL several years after GKRS.

    Methods: This cross-sectional study surveyed participants to assess hearing status, tinnitus, imbalance, vertigo, as well as the Short-Form 36-item Health Questionnaire (SF-36). Read More

    Voluminous laryngeal schwannoma excision with a mini-invasive external approach: a case report.
    Acta Otorhinolaryngol Ital 2017 Jun;37(3):242-244
    Department of Otolaryngology Head and Neck Surgery, San Raffaele Scientific Institute, Milan, Italy.
    Laryngeal schwannomas are extremely uncommon. We present a case of bulky supraglottic schwannoma with involvement of the preepiglottic and superior paraglottic spaces. Clinical findings, computed tomography and magnetic resonance images are presented. Read More

    Spectral Computed Tomography Imaging of Gastric Schwannoma and Gastric Stromal Tumor.
    J Comput Assist Tomogr 2017 May/Jun;41(3):417-421
    From the *The School of Nuclear Science and Technology, Lanzhou University; Departments of †Radiology and ‡Pathology, Lanzhou University Second Hospital; and §School of Stomatology, Lanzhou University, Lanzhou, China.
    Gastric schwannomas (GSs) and gastrointestinal stromal tumors (GSTs) are grossly similar submucosal neoplasms with different prognoses. We explored the value of spectral computed tomography (CT) to distinguish between them.

    Methods: Patients diagnosed with GS or GST at Lanzhou University Second Hospital, China, between May 2013 and June 2015 were included retrospectively. Read More

    Histotype-tailored neoadjuvant chemotherapy versus standard chemotherapy in patients with high-risk soft-tissue sarcomas (ISG-STS 1001): an international, open-label, randomised, controlled, phase 3, multicentre trial.
    Lancet Oncol 2017 Jun 9;18(6):812-822. Epub 2017 May 9.
    Department of Cancer Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy; Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy.
    Background: Previous trials from our group suggested an overall survival benefit with five cycles of adjuvant full-dose epirubicin plus ifosfamide in localised high-risk soft-tissue sarcoma of the extremities or trunk wall, and no difference in overall survival benefit between three cycles versus five cycles of the same neoadjuvant regimen. We aimed to show the superiority of the neoadjuvant administration of histotype-tailored regimen to standard chemotherapy.

    Methods: For this international, open-label, randomised, controlled, phase 3, multicentre trial, patients were enrolled from 32 hospitals in Italy, Spain, France, and Poland. Read More

    Geographic distribution of vestibular schwannomas in West Scotland between 2000-2015.
    PLoS One 2017 11;12(5):e0175489. Epub 2017 May 11.
    Department of Otolaryngology - Head and Neck Surgery, Queen Elizabeth University Hospital, Glasgow, United Kingdom.
    Background: Although the natural history of vestibular schwannomas (VS) has been previously studied, few studies have investigated associated epidemiological factors, primarily because of the lack of large available cohorts.

    Objective: The objective of this study was to perform a multi-scale geographical analysis of the period prevalence of VS in West Scotland from 2000 to 2015.

    Methods: Adults diagnosed with sporadic VS were identified through the National Health Services of West Scotland database and geocoded to the unit postcode. Read More

    Intraoral neurilemmoma of mental nerve mimicking as traumatic fibroma: An unusual presentation - A case report and literature review.
    J Oral Maxillofac Pathol 2017 Jan-Apr;21(1):124-128
    Department of Oral and Maxillofacial Pathology, Faculty of Dental Sciences, Sri Ramachandra Medical Centre, Chennai, Tamil Nadu, India.
    Neurilemmoma, neurinoma or schwannoma is a benign tumor of neurogenic origin, arising from the myelin sheath of a neuron. Head and neck region accounts for 25%-48% of these tumors reported till date. On the contrary, intraoral sites form only 1% of the cases accounted. Read More

    Small palatal swelling: an uncommon presentation of intraoral schwannoma.
    Gen Dent 2017 May-Jun;65(3):58-61
    Schwannomas are uncommon benign tumors arising in the nerve-supporting Schwann cells. Intraoral lesions usually present in the tongue or floor of the mouth as a submucosal nodule, while the palate is rarely affected. A 26-year-old white man presented with an asymptomatic submucosal fibroelastic nodule in the hard palate. Read More

    TIM-3 plays a more important role than PD-1 in the functional impairments of cytotoxic T cells of malignant Schwannomas.
    Tumour Biol 2017 May;39(5):1010428317698352
    Department of Neurosurgery, The Third Affiliated Hospital of Hebei Medical University, Shijiazhuang, china.
    Cancer immunotherapy using cytotoxic T cells demonstrates dramatic survival benefits in lymphomas, but its efficacy in solid tumors is limited. Here, we investigated the possibility of using cytotoxic T cells to treat malignant Schwannoma, a rare but aggressive nerve sheath tumor, by examining the native T-cell immunity in the host. We found that compared to CD8(+) T cells from healthy controls or benign Schwannoma patients, the CD8(+) T cells from malignant Schwannoma patients were present at normal frequencies but were substantially enriched with PD-1(-)TIM-3(+) and PD-1(+)TIM-3(+) cells. Read More

    Clinicopathologic features and immunohistochemical spectrum of 11 cases of epithelioid malignant peripheral nerve sheath tumors, including INI1/SMARCB1 results and BRAF V600E analysis.
    APMIS 2017 Aug 27;125(8):679-689. Epub 2017 Apr 27.
    Department of Pathology, Istanbul University, Capa School of Medicine, Istanbul, Turkey.
    Epithelioid malignant peripheral nerve sheath tumor (MPNST) is a rare, relatively less chemosensitive sarcoma. We report clinicopathologic features of 11 epithelioid MPNSTs, including rare forms, along with INI1 immunostaining and BRAF V600E mutation results. BRAF V600E mutation was tested by Real-time polymerase chain reaction (PCR) technique. Read More

    CyberKnife for Treatment of Vestibular Schwannoma: A Meta-analysis.
    Otolaryngol Head Neck Surg 2017 Jul 25;157(1):7-15. Epub 2017 Apr 25.
    1 Division of Neurotology and Skull Base Surgery, Department of Otolaryngology-Head and Neck Surgery, University of California, Irvine, California, USA.
    Objectives (1) Perform a meta-analysis of the available data on the outcomes of CyberKnife radiosurgery for treatment of vestibular schwannomas (VSs) in the published English-language literature and (2) evaluate the collective outcomes of CyberKnife treatment with respect to tumor control and hearing preservation. Data Sources A thorough literature search of published English-language articles was performed in the PubMed, Ovid, and Cochrane databases. Review Methods A database search was conducted with the keywords "CyberKnife" and "vestibular schwannoma" or "acoustic neuroma. Read More

    Hypoxia-induced miR-210 promoter demethylation enhances proliferation, autophagy and angiogenesis of schwannoma cells.
    Oncol Rep 2017 May 16;37(5):3010-3018. Epub 2017 Mar 16.
    Department of Orthopaedic Surgery, The Third Xiangya Hospital of Central South University, Changsha, Hunan 410011, P.R. China.
    Hypoxia, a dominant feature in cancer occurrence and evolution, exists throughout the progression of most malignant tumors. This study focused on the mechanism of hypoxia-induced miR-210 upregulation, and the miR-210 functions in schwannoma. We detected microvascular density, vascular endothelial growth factor (VEGF) and miR-210 expression levels using schwannoma tissue mciroarray. Read More

    Factors Influencing Cochlear Patency after Translabyrinthine Surgery.
    Otolaryngol Head Neck Surg 2017 Aug 18;157(2):269-272. Epub 2017 Apr 18.
    1 Michigan Ear Institute, Farmington Hills, Michigan, USA.
    Objective To determine predictive factors for cochlear obliteration after translabyrinthine surgery for vestibular schwannoma. Study Design Case series with chart review. Setting Neurotology referral center. Read More

    Generation of a human induced pluripotent stem cell (iPSC) line from a 64year old male patient with multiple schwannoma.
    Stem Cell Res 2017 Mar 21;19:49-51. Epub 2016 Dec 21.
    Department of Ophthalmology, The 2nd Hospital of Jilin University, Changchun 130041, China.
    Peripheral blood was collected from a clinically diagnosed 64-year old male multiple schwannoma patient. Peripheral blood mononuclear cells (PBMCs) were reprogrammed with the Yamanaka KMOS reprogramming factors using the Sendai-virus reprogramming system. The transgene-free iPSC line showed pluripotency verified by immunofluorescent staining for pluripotency markers, and the iPSC line was able to differentiate into the 3 germ layers in vivo. Read More

    Development of human induced pluripotent stem cell (iPSC) line from a 60year old female patient with multiple schwannoma.
    Stem Cell Res 2017 Mar 23;19:31-33. Epub 2016 Dec 23.
    Department of Ophthalmology, The 2nd Hospital of Jilin University, Changchun 130041, China.
    Peripheral blood was collected from a clinically diagnosed 60-year old female patient with multiple schwannoma. Peripheral blood mononuclear cells (PBMCs) were reprogrammed with the Yamanaka KMOS reprogramming factors using the Sendai-virus reprogramming system. The transgene-free iPSC line showed pluripotency verified by immunofluorescent staining for pluripotency markers, and the iPSC line was able to differentiate into the 3 germ layers in vivo. Read More

    Giant Schwannoma of ulnar nerve: case report.
    Rev Bras Ortop 2017 Mar-Apr;52(2):224-227. Epub 2016 Sep 20.
    Centro Hospitalar São João, Porto, Portugal.
    Schwannomas are the most common benign neoplasms of the peripheral nerves in the upper limbs. Although many are asymptomatic, they can produce a mass effect, thus impinging against soft tissues or interfering with joint function. The authors present a case report and a review of a giant Schwannoma in the ulnar nerve. Read More

    MULTIPLE INTRACRANIAL SCHWANNOMAS: CASE REPORT.
    Acta Clin Croat 2016 Jun;55(2):331-3
    Schwannomas are benign encapsulated tumors arising from the sheaths of peripheral nerves. They present as slowly enlarging solitary lumps, which may cause neurological defects. Multiple schwannomas in non-neurofi bromatosis type 2 patients are extremely rare. Read More

    The radiosurgery fractionation quandary: single fraction or hypofractionation?
    Neuro Oncol 2017 04;19(suppl_2):ii38-ii49
    Mayo Clinic, Rochester, Minnesota, MN, USA.
    Stereotactic radiosurgery (SRS), typically administered in a single session, is widely employed to safely, efficiently, and effectively treat small intracranial lesions. However, for large lesions or those in close proximity to critical structures, it can be difficult to obtain an acceptable balance of tumor control while avoiding damage to normal tissue when single-fraction SRS is utilized. Treating a lesion in 2 to 5 fractions of SRS (termed "hypofractionated SRS" [HF-SRS]) potentially provides the ability to treat a lesion with a total dose of radiation that provides both adequate tumor control and acceptable toxicity. Read More

    SMARCB1/INI1 Loss in Epithelioid Schwannoma: A Clinicopathologic and Immunohistochemical Study of 65 Cases.
    Am J Surg Pathol 2017 Aug;41(8):1013-1022
    Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
    The epithelioid variant of schwannoma is rare, and loss of SMARCB1/INI1 expression has been observed in a subset of cases. Our aim was to further define the clinicopathologic features and to evaluate SMARCB1/INI1 deficiency in a large cohort of 65 epithelioid schwannomas diagnosed between 2002 and 2015, which consisted of 32 men and 33 women with median age at diagnosis of 45 years (range, 13 to 75 y). Most tumors arose in the extremities (upper, 20, lower, 15) and trunk (17); 9 were visceral (8 gastrointestinal). Read More

    Vibration-induced nystagmus in patients with vestibular schwannoma: Characteristics and clinical implications.
    Clin Neurophysiol 2017 Jul 6;128(7):1372-1379. Epub 2017 Mar 6.
    Department of Otorhinolaryngology, Yonsei Univeristy College of Medicine, Seoul, South Korea. Electronic address:
    Objective: To investigate the clinical significance of vibration-induced nystagmus (VIN) in unilateral vestibular asymmetry and vestibular schwannoma.

    Methods: Thirteen patients with vestibular schwannoma underwent the VIN test, in which stimulation was applied to the mastoid processes and sternocleidomastoid (SCM) muscles on the ipsilateral and contralateral sides of lesions. Preoperative VIN was measured, and changes in VIN were followed up for 6months after tumor removal. Read More

    Immunohistochemical Approach to the Differential Diagnosis of Meningiomas and Their Mimics.
    J Neuropathol Exp Neurol 2017 04;76(4):289-298
    Pathology Department, Academic Hospital and Medicine University, INSERM U954, Université de Lorraine, Nancy, France
    The differential diagnosis between meningioma and others tumors can be challenging. This study aimed to evaluate different immunohistochemical markers for the differential diagnosis between meningioma and their morphological mimics. Immunohistochemistry was performed on tissue microarray with antiepithelial membrane antigen (EMA), progesterone receptor, somatostatin receptor 2A (SSTR2A), CD34, STAT6, S100, SOX10, HMB45, MelanA, GFAP, inhibin, and BCL2 antibodies. Read More

    Approaches to paraspinal tumours - a technical note.
    Neurol Res 2017 Apr 23;39(4):315-322. Epub 2017 Mar 23.
    a Lilavati Hospital and Research Centre , Mumbai , India.
    Neurogenic tumours of the paraspinal space can occur in all age groups. It is common in adult population and relatively rare in elderly group. Usually they are benign, but in children, arising from the autonomic system, tends to be malignant in nature. Read More

    Quality of Life in 807 Patients with Vestibular Schwannoma: Comparing Treatment Modalities.
    Otolaryngol Head Neck Surg 2017 Jul 7;157(1):92-98. Epub 2017 Mar 7.
    4 Department of Medical Decision Making, Leiden University Medical Center, Leiden, the Netherlands.
    Objective In vestibular schwannoma treatment, the choice among treatment modalities is controversial. The first aim of this study was to examine the quality of life of patients with vestibular schwannoma having undergone observation, radiation therapy, or microsurgical resection. The second aim was to examine the relationship between perceived symptoms and quality of life. Read More

    Ultrasound assessment of peripheral nerve pathology in neurofibromatosis type 1 and 2.
    Clin Neurophysiol 2017 May 20;128(5):702-706. Epub 2017 Feb 20.
    Center of Neurology, Tübingen University Hospital and Hertie Institute for Clinical Brain Research, Eberhard-Karl University Tübingen, Tübingen, Germany. Electronic address:
    Objective: The neurofibromatoses (NF) type 1 and 2 are hereditary tumor predisposition syndromes caused by germline mutations in the NF1 and NF2 tumor suppressor genes. In NF1 and 2, peripheral nerve tumors occur regularly. For further characterizing nerve ultrasound was performed in patients with NF1 and 2. Read More

    A rare thoracic intraspinal schwannoma in twin pregnancy with aggravated clinical presence: A case report following CARE.
    Medicine (Baltimore) 2017 Mar;96(11):e6327
    aDepartment of Neurosurgery, West China Hospital bDepartment of Nursing, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
    Introduction: This is the first case report about a thoracic intraspinal schwannoma in twin pregnancy with aggressive clinical presentation.

    Clinical Presence And Diagnoses: A 21-year-old woman presented with a 2-month history of back pain and slight lower extremity numbness and weakness, and her symptoms were misdiagnosed as normal reactions to pregnancy until she progressed to complete paralysis and incontinence within 2 weeks. She was then confirmed to have thoracic intraspinal schwannoma through MRI. Read More

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