4,160 results match your criteria Netherlands Journal of Medicine[Journal]


The "nodding head": a prognostic factor?

Neth J Med 2018 Dec;76(10):455-456

Department of Internal Medicine, Zaans Medisch Centrum Zaandam, the Netherlands.

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December 2018

Moderate increase of serum levels of procalcitonin in diabetic ketoacidosis.

Neth J Med 2018 Dec;76(10):454

Unita Operativa Medicina d Urgenza e Pronto Soccorso, AOUP, Pisa, Italy.

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December 2018

Answer to Photo Quiz: Progressive visual decline in a Rotterdam harbor crane operator.

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Neth J Med 2018 Dec;76(10):453

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December 2018

Progressive visual decline in a Rotterdam harbor crane operator.

Neth J Med 2018 Dec;76(10):452

Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, the Netherlands.

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December 2018

Crusted cutaneous lesions requiring early diagnosis and appropriate treatment.

Neth J Med 2018 Dec;76(10):450

Unité de Dermatologie, Hôpital René Dubos, Pontoise, France.

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December 2018

Central diabetes insipidus: beware of Langerhans cell histiocytosis!

Neth J Med 2018 Dec;76(10):445-449

Department of Internal Medicine, Maastricht University Medical Centre, the Netherlands.

Langerhans cell histiocytosis (LCH) is a rare disorder, characterised by a monoclonal proliferation of aberrant histiocytes that accumulate in and infiltrate into different organs. When the hypothalamic-pituitary axis is involved, central diabetes insipidus (CDI) can be its first manifestation. Three cases of LCH with central diabetes insipidus were retrospectively analyzed: Case 1 is a 41-year old female presenting with polyuria and polydipsia. Read More

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December 2018
1 Read

Macrophage activation syndrome with lung involvement complicating adult-onset Still's disease.

Neth J Med 2018 Dec;76(10):442-444

Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.

Adult-onset Still's disease (AOSD) can progress into macrophage activation syndrome (MAS), which may be fatal. We report on a 19-year-old Han Chinese female, who presented with MAS-related pulmonary parenchymal involvement complicating AOSD, and further associated with disseminated intravascular coagulation and generalized tonic-clonic seizure. She was managed by high-dose corticosteroids and pulse cyclophosphamide therapy with a complete recovery of disease activity. Read More

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December 2018
2 Reads

Hypereosinophilia: a diagnostic challenge.

Neth J Med 2018 Dec;76(10):431-436

Harbour Hospital and Institute for Tropical Diseases, Rotterdam, the Netherlands (currently working at Albert Schweitzer Hospital, Rotterdam).

Hypereosinophilia encompasses a broad differential diagnosis of atopy/allergic reactions, drug reactions, parasitic infections and paraneoplastic syndromes. Although mostly of limited clinical significance, hypereosinophilia can also be related to hematological malignancies. One has to be aware of the potential for secondary organ damage for example, in the case of hypereosinophilic syndrome. Read More

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December 2018
2 Reads

Trends in direct oral anticoagulant (DOAC) use: health benefits and patient preference.

Neth J Med 2018 Dec;76(10):426-430

Unit of PharmacoTherapy, PharmcoEpidemiology and PharmcoEconomics, University of Groningen, Groningen, the Netherlands.

In 2012, the Dutch Health Council published a report addressing barriers for an early and broad introduction of direct oral anticoagulants (DOACs). The report raised concerns about the lack of an antidote, adherence, lack of monitoring in the case of overdose and the increased budget impact at DOAC introduction. In the past decade, international studies have shown that DOACs can provide healthcare benefits for a large number of patients. Read More

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December 2018

Efficacy and safety of a phosphate replacement strategy for severe hypophosphatemia in the ICU.

Neth J Med 2018 Dec;76(10):437-441

Department of Internal Medicine, Rijnstate Hospital, Arnhem, the Netherlands.

Background: Experience with individualized phosphate replacement is limited in patients with severe hypophosphatemia. This study compares the efficacy and safety of an individualized regimen of serum phosphate < 0.4 mmol/l treatment in ICU patients to patients with moderate hypophosphatemia (0. Read More

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December 2018
1 Read

Adult-onset Still's disease: autoinflammation beyond fever.

Authors:
P L A van Daele

Neth J Med 2018 Dec;76(10):425

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December 2018

Assessment of physicians' cognitive biases.

Neth J Med 2018 Nov;76(9):422-424

Department of Internal Medicine, OLVG, Amsterdam, the Netherlands.

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November 2018

Answer to Photo Quiz: A woman with a purplish-red skin lesion on the neck.

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Neth J Med 2018 Nov;76(9):421

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November 2018
6 Reads

A woman with a purplish-red skin lesion on the neck.

Neth J Med 2018 Nov;76(9):420

Department of Dermatology, Albert Schweitzer Hospital, Dordrecht, the Netherlands.

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November 2018
8 Reads

Answer to Photo Quiz: Out of pace: An uncommon cause of atrioventricular block.

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Neth J Med 2018 Nov;76(9):419

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November 2018
1 Read

Out of pace: An uncommon cause of atrioventricular block.

Neth J Med 2018 Nov;76(9):418

Department of Internal Medicine, Ikazia Hospital, Rotterdam, the Netherlands Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands.

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November 2018
1 Read

Itching dermatitis on the leg of a 46-year-old HIV-positive man from Jamaica.

Neth J Med 2018 Nov;76(9):415-416

Departments of Integrated Care, Maastricht University Medical Centre, Maastricht, the Netherlands.

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November 2018
1 Read

Allergic acute coronary syndrome in exercise-induced anaphylaxis.

Neth J Med 2018 Nov;76(9):411-414

Departments of Acute Care, Erasmus Medical Center, Rotterdam, the Netherlands.

In this case report we present a 49-year-old male who was seen in the emergency department after collapsing due to anaphylactic shock, with ECG findings suggesting myocardial ischaemia. We linked both diagnoses to Kounis syndrome, which describes an acute coronary syndrome due to an allergic event. His circulatory collapse was explained by exercise-induced anaphylaxis. Read More

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November 2018
9 Reads

Progressive kidney failure in chronic myelomonocytic leukaemia: don't forget lysozyme damage.

Neth J Med 2018 Nov;76(9):407-410

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.

Kidney failure is common in haematologic malignancies. However, the nephrotoxic effect of lysozyme is seldom recognized. We present a 78-year-old male with chronic myelomonocytic leukaemia who developed progressive kidney failure due to increased production of lysozyme. Read More

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November 2018
1 Read

Taking care of the multimorbid patient, a primary task of the internist.

Neth J Med 2018 Nov;76(9):388

Department of Internal Medicine, Section Geriatric Medicine, Erasmus MC, Rotterdam, the Netherlands.

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November 2018
7 Reads

Secondary care experiences of patients with multiple chronic conditions.

Neth J Med 2018 Nov;76(9):397-406

Departments of Geriatrics, Gelre Hospitals, Apeldoorn, the Netherlands.

Background: This study aimed to investigate patients' experiences, beliefs and understandings of the current secondary care of patients with multiple chronic conditions (MCC) in the Netherlands.

Methods: A qualitative, interpretative description design was used. We conducted semi-structured, in-depth interviews with patients with MCC, who visited at least two physicians in Gelre Hospitals for at least two appointments in the previous year. Read More

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November 2018

Relevance of healthcare-associated pneumonia for empirical antibiotic therapy in the Netherlands.

Neth J Med 2018 Nov;76(9):389-396

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.

Background: There is no consensus whether patients with healthcare-associated pneumonia (HCAP) should be considered as a patient with hospital-acquired pneumonia (HAP) and treated with broad-spectrum antibiotics, or as a patient with community-acquired pneumonia (CAP), and treated with narrow-spectrum antibiotics. HCAP research has focused mostly on the predictive value for non-susceptibility to broad-spectrum antibiotics and multi-drug resistant pathogens, in settings with moderate to high levels of antibiotic resistance. We investigated whether HCAP criteria predicts non-susceptibility to different empirical strategies, including narrow-spectrum antibiotics in the Dutch setting. Read More

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November 2018
13 Reads

Hyponatraemia related to hypopituitarism.

Authors:
G Decaux

Neth J Med 2018 Oct;76(8):387

Department of Internal Medicine, Erasmus University Hospital, Brussels, Belgium.

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October 2018
1 Read

Answer to Photo Quiz: A granulomatous inflammation in a renal transplant biopsy.

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Neth J Med 2018 Oct;76(8):386

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October 2018

A granulomatous inflammation in a renal transplant biopsy.

Neth J Med 2018 Oct;76(8):385

Department of Pathology, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.

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October 2018
15 Reads

Answer to Photo Quiz: Back and joint pain according to good old Virchow.

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Neth J Med 2018 Oct;76(8):384

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October 2018

Back and joint pain according to good old Virchow.

Neth J Med 2018 Oct;76(8):383

Department of Internal Medicine, Reinier de Graaf Hospital, Delft, the Netherlands.

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October 2018

Answer to Photo Quiz: Jaundice and fever in a patient with psoriasis.

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Neth J Med 2018 Oct;76(8):382

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October 2018

Jaundice and fever in a patient with psoriasis.

Neth J Med 2018 Oct;76(8):381

Infection Department, Medilife Hospital, Istanbul, Turkey.

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October 2018
6 Reads

Urine changing from clear to milky-white.

Neth J Med 2018 Oct;76(8):379-380

Department of Intensive Care Medicine, Hospital Group Twente, Almelo, the Netherlands.

After sedation with propofol a young man developed milky-white urine. Urinalysis showed a high concentration of uric acid crystals as being responsible. This phenomenon appears to be dose-dependent and is explained in this report. Read More

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October 2018

Case series on acute HCV in HIV-negative men in regular clinical practice: a call for action.

Neth J Med 2018 Oct;76(8):374-378

Department of Internal Medicine and Infectious Diseases, Erasmus MC, Rotterdam, the Netherlands.

Background: The evidence that HIV treatment as prevention (TasP) and HIV pre-exposure prophylaxis (PrEP) reduces the risk of HIV transmission is overwhelming. But as PrEP and TasP can lead to increased sexual mixing between HIV positive and negative men who have sex with men (MSM), sexually transmitted infections such as acute hepatitis C (HCV), which were thought to be limited to HIV-infected MSM, could become more frequent in HIV uninfected MSM as well. The objective of this study was to describe a series of cases of sexually transmitted HCV infections in HIV-uninfected MSM in the Netherlands and Belgium. Read More

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October 2018
4 Reads

When to stop colonoscopy surveillance in the elderly?

Neth J Med 2018 Oct;76(8):350

Department of Gastroenterology, Erasmus University Medical Centre, Rotterdam, the Netherlands.

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October 2018

Variable workup calls for guideline development for type 2A hereditary haemochromatosis.

Neth J Med 2018 Oct;76(8):365-373

Radboud University Medical Centre for Iron Disorders, Nijmegen, the Netherlands; Department of Laboratory Medicine, Translational Metabolic Laboratory, Radboud University Medical Centre, Nijmegen, the Netherlands.

Background: Type 2A hereditary haemochromatosis (type 2A HH) is a rare iron-loading disorder caused by mutations in the HFE2 gene, which encodes the HJV protein. We present characteristics, treatment and follow-up of subjects diagnosed with type 2A HH in the Netherlands to increase awareness of the disease and its treatment, and to define knowledge gaps.

Methods: We collected clinical, biochemical and genetic data from seven patients (two female; five probands) from six families genetically diagnosed with type 2A HH at the Expertise Center for Iron Disorders, Radboud University Medical Centre between 2006 and 2016. Read More

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October 2018
13 Reads

Adherence to surveillance guidelines for colorectal adenomatous polyps in the elderly.

Neth J Med 2018 Oct;76(8):358-364

Department of Internal Medicine, Diakonessenhuis, Utrecht, the Netherlands Department of Geriatric Medicine, Diakonessenhuis, Zeist, the Netherlands.

Objective: Determining adherence to recommended surveillance intervals after polypectomy in elderly patients.

Design: A retrospective cohort study including 531 patients aged above 70 years undergoing polypectomy between 2009-2011 in a large Dutch teaching hospital, identified using the hospital's pathology registry. Outcomes of the index colonoscopy were reviewed. Read More

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October 2018
16 Reads

The impact of laboratory closing times on delay of adequate therapy in blood stream infections.

Neth J Med 2018 Oct;76(8):351-357

Department of Internal Medicine, VU University Medical Centre Amsterdam, Amsterdam, the Netherlands.

Background: Patients with bloodstream infections need early adequate antimicrobial treatment to reduce mortality. This raises the question of timing and logistics. How important is the time of day when a culture is flagged positive to the processing of blood cultures and optimisation of antimicrobial therapy?

Methods: We performed a retrospective study assessing the time delay of a positive blood culture result during and after office hours and its impact on adequate antimicrobial therapy. Read More

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October 2018
6 Reads

Q fever: hospitalisation and other concerns.

Authors:
V M Dos Santos

Neth J Med 2018 Sep;76(7):349

Internal Medicine, Catholic University and Armed Forces Hospital, Brasília-DF, Brazil.

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September 2018
2 Reads

Answer to Photo Quiz: Ulcerated nodules of the tongue.

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Neth J Med 2018 Sep;76(7):348

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September 2018

Ulcerated nodules of the tongue.

Neth J Med 2018 Sep;76(7):347

Department of Interdisciplinary Medicine, Complex Operating Unit of Odontostomatology, Aldo Moro University of Bari, Bari, Italy.

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September 2018

Answer to Photo Quiz: Swelling of the breast after cosmetic augmentation.

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Neth J Med 2018 Sep;76(7):346

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September 2018
1 Read

Swelling of the breast after cosmetic augmentation.

Neth J Med 2018 Sep;76(7):345

Departmentsof Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands.

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September 2018
1 Read

Answer to Photo Quiz: Hemothorax: a very rare complication of late diaphragmatic hernia.

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Neth J Med 2018 Sep;76(7):344

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September 2018
1 Read

Hemothorax: a very rare complication of late diaphragmatic hernia.

Neth J Med 2018 Sep;76(7):343

Emergency Department, Wan Fang Hospital, Taipei Medical University, Taipei.

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September 2018
1 Read

Subacute renal injury in hypothyroidism: a case report of an unusual phenomenon.

Neth J Med 2018 Sep;76(7):339-342

Department of Internal Medicine, Northwest Clinics, location Alkmaar, the Netherlands.

Severe hypothyroidism is known to cause elevation of creatinine and this phenomenon has been reported in clinical settings in the past. Screening for hypothyroidism is not regularly performed in the differential workup for acute kidney injury due to its rare presentation. Therefore, to most physicians hypothyroidism is not known as a cause of acute kidney injury. Read More

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September 2018
2 Reads

Ticking off diagnoses of abdominal pain: early neuroborreliosis with radiculopathy.

Neth J Med 2018 Sep;76(7):336-338

Department of Internal Medicine, Haga Teaching Hospital, the Hague, the Netherlands.

Lyme disease (LD) is the most common tick-borne illness. The diagnosis of LD is difficult because of the great variation in clinical manifestations. Although abdominal pain is generally not considered a sign of LD, in this case report we describe a patient with unexplained severe abdominal pain that eventually turned out to be LD due to radiculopathy. Read More

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September 2018
1 Read

Coronary artery spasms due to tyrosine kinase inhibitors used in chronic myeloid leukemia.

Neth J Med 2018 Sep;76(7):330-335

Department of Hematology, Erasmus University Medical Center, Rotterdam, the Netherlands.

Tyrosine kinase inhibitors (TKIs) have changed the landscape of treatment for patients with chronic myeloid leukemia (CML) leading to a life expectancy comparable to the general population. Side effects commonly encountered during TKI treatment are pleural effusion due to use of dasatinib and vascular side effects due to nilotinib and ponatinib. Coronary artery spasm (CAS), although encountered during treatment with other chemotherapeutic drugs, have to our knowledge never been reported during TKI treatment. Read More

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September 2018
1 Read

Management of S. aureus bacteraemia in the Netherlands; infectious diseases consultation improves outcome.

Neth J Med 2018 Sep;76(7):322-329

Department of Medical Microbiology, Maastricht UMC+, Maastricht, the Netherlands.

Background: Staphylococcus aureus bacteraemia is associated with a high mortality rate. Previously it has been shown that consultation by an internist-infectious diseases specialist (IDS) improves the outcome of patients. In this study, we evaluated the differences in management and outcome between patients with, and those without IDS consultation. Read More

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September 2018
7 Reads

Occurrence and management of an aberrant free T4 in combination with a normal TSH.

Neth J Med 2018 Sep;76(7):314-321

Department of Internal Medicine, Isala Hospital (previously employed by Department of Internal Medicine, Alrijne Hospital), Zwolle, the Netherlands.

Background: Thyroid function tests may show the combination of a normal concentration of serum thyroidstimulating hormone (TSH) and an increased or decreased level of free thyroxine (free T4). How often this occurs is unclear and not everyone is familiar with how it should be adressed.

Methods: We conducted a retrospective cohort study of all adult patients who presented at a non-academic general hospital in the Netherlands between 1 January 2010 and 31 December 2014 and yielded an increased or decreased free T4 in combination with a normal TSH. Read More

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September 2018

Pitfalls in cytokine measurements - Plasma TGF-β1 in chronic fatigue syndrome.

Neth J Med 2018 Sep;76(7):310-313

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.

Background: Serum TGF-β1 concentrations are reported to be elevated in chronic fatigue syndrome (CFS). However, measurement of circulating cytokines is a complex procedure and control of pre-analytical procedures is essential. The objective of the current study was to measure circulating TGF-β1 concentrations in CFS patients compared to healthy controls, taking into account differences in pre-analytical procedures. Read More

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September 2018
5 Reads