235 results match your criteria Nerve Block Sural

The effect of posterior tibial and sural nerve blocks on postoperative pain of patients following open reduction and internal fixation of calcaneal fractures.

Foot Ankle Surg 2021 Nov 24. Epub 2021 Nov 24.

Orthopedic Foot and Ankle Surgeon, Department of Orthopedic Surgery, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address:

Introduction: Postoperative pain control and achieving opioid-free anesthesia are major issues for surgically treated patients with calcaneal fractures. We evaluated the potential role of posterior tibial and sural nerve blocks as a part of multimodal pain control techniques in patients underwent open reduction and internal fixation (ORIF) of calcaneal fractures via extensile lateral approach.

Methods: Forty-eight patients randomly allocated to receive either posterior tibial and sural nerve blocks with bupivacaine (peripheral nerve block (PNB) group) or normal saline, after induction of general anesthesia. Read More

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November 2021

Overview of the Innervation of Ankle Joint.

Phys Med Rehabil Clin N Am 2021 11 14;32(4):791-801. Epub 2021 Jul 14.

Division of Anatomy, Department of Surgery, Temerty Faculty of Medicine, University of Toronto, 1 King's College Circle, Room 1158, Toronto, ON M5S 1A8, Canada.

In this article, the literature describing the origin, course, and termination of the nerves innervating the ankle joint is reviewed and discussed. The anterior aspect of the joint capsule receives innervation from articular branches from the saphenous, superficial, and deep fibular nerves; laterally from the sural and superficial fibular nerves; and medially and posteriorly from the saphenous and tibial nerves. Comprehensive mapping of the trajectory, spatial relationships, and termination of the articular branches innervating the ankle joint capsule will aid in developing new and improving existing image-guided nerve block and radiofrequency ablation protocols to treat chronic joint pain. Read More

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November 2021

[Neuropathy presenting conduction block in ANCA-negative eosinophilic granulomatosis with polyangiitis].

Rinsho Shinkeigaku 2021 Sep 26;61(9):613-617. Epub 2021 Aug 26.

Department of Neurology and Clinical Neuroscience, Yamaguchi University Graduate School of Medicine.

A 74-year-old woman with a history of asthma and allergic rhinitis rapidly developed multiple mononeuropathy. Although anti-neutrophil cytoplasmic antibodies were negative, the presence of eosinophilia and eosinophilic infiltrations in the sural nerve led to a diagnosis of eosinophilic granulomatosis with polyangiitis. A motor nerve conduction study on admission revealed conduction block, which promptly disappeared after initiating immunotherapy without findings suggestive for remyelination or axonal degeneration. Read More

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September 2021

Bifurcation of the sciatic nerve: A descriptive study on a South African cadaver cohort.

Morphologie 2021 May 26. Epub 2021 May 26.

Division of Clinical Anatomy, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, Western Cape, South Africa. Electronic address:

Background: The sciatic nerve bifurcates into the tibial and common fibular nerves in six different regions: the pelvic region, gluteal region, proximal, middle, or distal third of the posterior thigh, or in the popliteal fossa. Inadequate knowledge of sciatic nerve anatomy could lead to failed nerve blocks, and damage during intramuscular injections. Limited studies have been done on African population groups and lack a quantifiable method to classify the levels of sciatic nerve bifurcation. Read More

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Electrophysiological Study of the Tibial Nerve Across the Tarsal Tunnel in Distal Symmetric Diabetic Polyneuropathy.

Am J Phys Med Rehabil 2022 02;101(2):152-159

From the EMG Service, Local Health Unit Toscana Sud Est, Siena, Italy (MM, AA); and Department of Medical, Surgical and Neurological Sciences, University of Siena, Siena, Italy (FG).

Objective: The aim of the study was to demonstrate abnormalities of motor conduction of the tibial nerve across the tarsal tunnel in type 2 diabetes.

Design: One hundred twenty-four consecutive patients (mean age = 66.6 yrs, 62. Read More

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February 2022

Utility of Neuropathy Screening for Wild-Type Transthyretin Amyloidosis Patients.

Can J Neurol Sci 2021 09 21;48(5):607-615. Epub 2020 Dec 21.

Division of Cardiology, Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

Background: Wild-type transthyretin amyloidosis (wtATTR) is an important cause of heart failure (HF); however, the prevalence and clinical significance of neurologic complications remains uncertain.

Methods: This analysis reports findings from a single-centre experience of routine neuropathy screening at the time of wtATTR diagnosis by nerve conduction studies and neurologist assessment, compared with age-matched controls.

Results: Forty-one wtATTR patients were included, 39 (95%) males, mean age 78. Read More

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September 2021

Dissociation of axo-glial junction in anti-neurofascin 155 chronic inflammatory demyelinating polyneuropathy.

Clin Neuropathol 2021 Mar-Apr;40(2):87-92

Aims: A subset of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is characterized by the presence of anti-neurofascin 155 (anti-NF155) autoantibodies. In this paper, we investigated an anti-NF155 CIDP patient via clinical, electrophysiological, and neuropathological tests.

Materials And Methods: The patient was a 15-year-old Chinese boy affected by distal limb weakness and tremor for a 6-month period. Read More

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January 2022

Outcome After Modified Grice-Green Procedure (SAMBB) for Arthritic Acquired Adult Flatfoot.

Foot Ankle Int 2020 Nov 11;41(11):1404-1410. Epub 2020 Aug 11.

I Clinic of Orthopaedics and Traumatology, Istituto Ortopedico Rizzoli, Bologna, Italy.

Background: Adult acquired flatfoot deformity is a well-known and recognized cause of pain and disability. The purpose of this retrospective study was to describe radiographic and clinical outcomes of the modified mini bone block distraction subtalar arthrodesis (SAMBB) in adult patients affected by adult flatfoot with subtalar joint osteoarthritis at a midterm mean follow-up.

Methods: A retrospective review of our database identified patients. Read More

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November 2020

Nerve Blocks: Part II. Lower Extremity.

Am Fam Physician 2020 06;101(11):669-679

Uniformed Services University of the Health Sciences, Bethesda, MD, USA.

Family physicians use anesthesia to provide diagnostic and procedural analgesia for conditions such as neuropathies, fracture reduction, foreign body removals, and complex wound management. Local infiltration of anesthetics is commonly used in this setting because of the ease of use, safety, and effectiveness of the procedure. Nerve blocks are a specific regional anesthesia technique that blocks nerve function distal to the injection site. Read More

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Pmp22 super-enhancer deletion causes tomacula formation and conduction block in peripheral nerves.

Hum Mol Genet 2020 06;29(10):1689-1699

Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, USA.

Copy number variation of the peripheral nerve myelin gene Peripheral Myelin Protein 22 (PMP22) causes multiple forms of inherited peripheral neuropathy. The duplication of a 1.4 Mb segment surrounding this gene in chromosome 17p12 (c17p12) causes the most common form of Charcot-Marie-Tooth disease type 1A, whereas the reciprocal deletion of this gene causes a separate neuropathy termed hereditary neuropathy with liability to pressure palsies (HNPP). Read More

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Habituation of the Interlimb Reflex (ILR) Over the Biceps Brachii Muscle After Electrical Stimuli Over the Sural Nerve.

Front Neurosci 2019 23;13:1130. Epub 2019 Oct 23.

Department of Neurology, Martin Luther University of Halle-Wittenberg, Halle (Saale), Germany.

Up to now relatively little is known about interlimb reflexes (ILR). Especially it is not well known whether ILR may habituate or not to subsequent stimuli. The main aim of the present investigation was to explore the short term habituation behavior of ILR. Read More

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October 2019

An Anatomic and Clinical Study of the Innervation of the Dorsal Midfoot Capsule.

Foot Ankle Int 2019 Oct 23;40(10):1209-1213. Epub 2019 Jul 23.

Department of Orthopedic Surgery, Medical College of Wisconsin, Milwaukee, WI, USA.

Background: Dorsal pain from osteoarthritic midfoot joints is thought to be relayed by branches of the medial and lateral plantar, sural, saphenous, and deep peroneal nerves (DPN). However, there is no consensus on the actual number or pathways of the nervous branches for midfoot joint capsular innervation. This study examined the DPN's terminal branches at the midfoot joint capsules through anatomic dissection and confirmation of their significance in a clinical case series of patients with midfoot pain relief after DPN block. Read More

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October 2019

Ultrasound-guided ankle block. History revisited.

Best Pract Res Clin Anaesthesiol 2019 Mar 7;33(1):79-93. Epub 2019 May 7.

Department of Anaesthesiology, University Hospitals of the KU Leuven, Herestraat 49, 3000, Leuven, Belgium.

Following forefoot surgery, compared to the traditional multimodal approach, regional anesthesia and analgesia provides high quality pain relief, decreases opioids consumption and leads to very high satisfaction scores. Traditional regional techniques relied either on wound infiltration, landmark technique ankle blocks or popliteal sciatic nerve block. Numerous anatomic variations of the different nerves might lead to failure following a blind technique. Read More

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Sagittal Resection Osteotomy With Bone Block Distraction Subtalar Fusion for Treatment of Malunited Calcaneal Fractures.

J Foot Ankle Surg 2019 Jul 1;58(4):739-747. Epub 2019 May 1.

Orthopedic Resident, Elhadara University Hospital, Elhadara, Lambrouzou, Alexandria, Egypt.

The aim of this prospective study was to evaluate the results of combined lateral sagittal resection osteotomy with subtalar distraction fusion in heels with painful malunion of the os calcis. This case series included 22 patients (23 feet). The mean age of the patients was 37. Read More

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Randomized Controlled Trial of Physical Exercise in Diabetic Veterans With Length-Dependent Distal Symmetric Polyneuropathy.

Front Neurosci 2019 11;13:51. Epub 2019 Feb 11.

Research Service, Department of Veterans Affairs, Edward Hines Jr. VA Hospital, Hines, IL, United States.

Physical exercise is an essential adjunct to the management of patients with type 2 diabetes mellitus. Therapeutic interventions that improve blood flow to peripheral nerves, such as exercise, may slow the progression of neuropathy in the diabetic patient. This randomized clinical trial was conducted to determine whether a structured program of aerobic, isokinetic strength, or the combination of aerobic-isokinetic strength exercise intervention alters peripheral nerve function in glycemic-controlled diabetic patients with advanced length-dependent distal symmetric polyneuropathy. Read More

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February 2019

Injection-related iatrogenic peripheral nerve injuries: Surgical experience of 354 operated cases.

Neurol India 2019 Jan-Feb;67(Supplement):S82-S91

Department of Neurosurgery, PD Hinduja Hospital, Mumbai, Maharashtra, India.

Objective: A retrospective analysis of surgically treated 354 cases of injection-related iatrogenic peripheral nerve injuries was performed. The purpose of this clinical study was to present our experience in the management of various types of injection-related peripheral nerve injuries and discuss various issues that are associated with this subset of peripheral nerve injuries.

Methods: Over a 17-year period, 354 cases of injection-related iatrogenic peripheral nerve injuries were managed surgically at the Department of Neurosurgery at P. Read More

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December 2019

'SCALD-ED' Block: Superficial Cutaneous Anesthesia in a Lateral Leg Distribution within the Emergency Department - A Case Series.

J Emerg Med 2019 Mar 9;56(3):282-287. Epub 2019 Jan 9.

Department of Emergency Medicine, Rutgers New Jersey Medical School, Newark, New Jersey.

Background: In the midst of a nationwide opioid epidemic, focus has been placed on identifying and utilizing safe, effective opioid-free analgesic alternatives. Lower-extremity peripheral nerve blockades are common and often involve both motor and sensory anesthesia, resulting in leg weakness and ambulatory difficulty. The aim of this case report is to describe an ultrasound-guided peripheral nerve block technique (superficial cutaneous anesthesia in a lateral (leg) distribution within the emergency department ['SCALD-ED' block]) that provides motor-sparing, purely sensory anesthesia after a superficial injury to the lateral leg in patients presenting to the emergency department. Read More

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Anti-neurofascin autoantibody and demyelination.

Neurochem Int 2019 11 22;130:104360. Epub 2018 Dec 22.

Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

Demyelination diseases involving the central and peripheral nervous systems are etiologically heterogeneous with both cell-mediated and humoral immunities playing pathogenic roles. Recently, autoantibodies against nodal and paranodal proteins, such as neurofascin186 (NF186), neurofascin155 (NF155), contactin-1 (CNTN1), contactin-associated protein 1 (CASPR1) and gliomedin, have been discovered in not only chronic demyelinating conditions, such as multiple sclerosis (MS) and chronic inflammatory demyelinating polyradiculoneuropathy, but also in acute demyelinating conditions, such as Guillain-Barré syndrome. Only a minority of these patients harbor anti-nodal/paranodal protein antibodies; however, these autoantibodies, especially IgG4 subclass autoantibodies to paranodal proteins, are associated with unique features and these conditions are collectively termed nodopathy or paranodopathy. Read More

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November 2019

Very Early Neurophysiological Study in Guillain-Barre Syndrome.

Eur Neurol 2018 22;80(1-2):100-105. Epub 2018 Oct 22.

Department of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an,

Purpose: The diagnosis of Guillain-Barre syndrome (GBS) in the very early stage may be challenging. Our aim was to report the neurophysiological abnormalities in GBS within 4 days of clinical onset. We expected that GBS will be diagnosed by the assistance of neurophysiological study in the very early stage. Read More

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January 2019

Peripheral neuropathy in Tangier disease: A literature review and assessment.

J Peripher Nerv Syst 2018 Jun 8;23(2):88-98. Epub 2018 May 8.

Department of Molecular Medicine, Bakirkoy Dr. Sadi Konuk Research and Training Hospital, Istanbul, Turkey.

Tangier disease (TD) (OMIM#205400) is a rare cause of inherited metabolic neuropathies characterized by marked deficiency of high-density lipoproteins and accumulation of cholesterol esters in various tissue resulting from reverse cholesterol transport deficiency. We report a case of a patient with TD with multifocal demyelinating neuropathy with conduction block who presents with winging scapula, tongue, and asymmetric extremity weakness. We also present a review of all studies published from 1960 to 2017 regarding peripheral neuropathy in TD. Read More

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Guillain-Barré Syndrome.

Peter D Donofrio

Continuum (Minneap Minn) 2017 Oct;23(5, Peripheral Nerve and Motor Neuron Disorders):1295-1309

Purpose Of Review: This article reviews the current state of Guillain-Barré syndrome (GBS), including its clinical presentation, evaluation, pathophysiology, and treatment.

Recent Findings: GBS is an acute/subacute-onset polyradiculoneuropathy typically presenting with sensory symptoms and weakness over several days, often leading to quadriparesis. Approximately 70% of patients report a recent preceding upper or lower respiratory tract infection or gastrointestinal illness. Read More

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October 2017

Ultrasound-guided therapeutic injections for neural pathology about the foot and ankle: a 4 year retrospective review.

Skeletal Radiol 2017 Jun 16;46(6):795-803. Epub 2017 Mar 16.

Center for Musculoskeletal Care, New York University Langone Medical Center, New York, NY, USA.

Objective: To describe a 4-year clinical experience with ultrasound-guided therapeutic perineural injections of peripheral nerves about the foot and ankle.

Materials And Methods: Retrospective analysis of foot and ankle perineural injections performed between January 2012 and August 2016. Demographics, clinical indications, presence of structural pathology, immediate and interval pain relief, as well as complications were recorded. Read More

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The mechanistic basis for photobiomodulation therapy of neuropathic pain by near infrared laser light.

Lasers Surg Med 2017 07 11;49(5):516-524. Epub 2017 Jan 11.

Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814.

Background And Objective: Various irradiances have been reported to be beneficial for the treatment of neuropathic pain with near infrared light. However, the mechanistic basis for the beneficial outcomes may vary based on the level of irradiance or fluence rate used. Using in vivo and in vitro experimental models, this study determined the mechanistic basis of photobiomodulation therapy (PBMT) for the treatment of neuropathic pain using a high irradiance. Read More

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Dexmedetomidine Added to Local Anesthetic Mixture of Lidocaine and Ropivacaine Enhances Onset and Prolongs Duration of a Popliteal Approach to Sciatic Nerve Blockade.

Clin Ther 2017 Jan 10;39(1):89-97.e1. Epub 2016 Dec 10.

Department of Anaesthesiology, First Affiliated Hospital, Wenzhou Medical University, Zhejiang, China. Electronic address:

Purpose: A literature review of multiple clinical studies on mixing additives to improve pharmacologic limitation of local anesthetics during peripheral nerve blockade revealed inconsistency in success rates and various adverse effects. Animal research on dexmedetomidine as an adjuvant on the other hand has promising results, with evidence of minimum unwanted results. This randomized, double-blinded, contrastable observational study examined the efficacy of adding dexmedetomidine to a mixture of lidocaine plus ropivacaine during popliteal sciatic nerve blockade (PSNB). Read More

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January 2017

[Clinical and electrophysiological characteristics and therapeutic analysis of 9 patients with Lewis-Sumner syndrome].

Zhonghua Yi Xue Za Zhi 2016 Mar;96(11):859-62

Department of Neurology, Peking University Third Hospital, Beijing 100191, China.

Objective: To investigate the clinical characteristics, electrophysiological findings and treatment response of Lewis-Sumner syndrome (LSS).

Methods: Data of nine patients with LSS, who were diagnosed and treated from May 2008 to August 2014 in Department of Neurology, Peking University Third Hospital, were analyzed retrospectively, including clinical features, electrophysiological studies, pathological characteristics, therapy and follow up.

Results: The nine cases included seven males and two females, with the average age being 29 years old (18-64 years old). Read More

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Workup and Management of Persistent Neuralgia following Nerve Block.

Case Rep Anesthesiol 2016 19;2016:9863492. Epub 2016 Jan 19.

University of California San Francisco School of Medicine, San Francisco, CA, USA.

Neurological injuries following peripheral nerve blocks are a relatively rare yet potentially devastating complication depending on the type of lesion, affected extremity, and duration of symptoms. Medical management continues to be the treatment modality of choice with multimodal nonopioid analgesics as the cornerstone of this therapy. We report the case of a 28-year-old man who developed a clinical common peroneal and lateral sural cutaneous neuropathy following an uncomplicated popliteal sciatic nerve block. Read More

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February 2016

N-hexane neuropathy with vertigo and cold allodynia in a silk screen printer: A case study.

Int J Occup Med Environ Health 2015 ;28(5):915-9

Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India (Department of Neurology).

N-hexane neuropathy is an occupational disease caused by exposure to n-hexane, which is used as a solvent in silk screen printing. Here, we describe a 35-year-old man, a silk screen printer by profession, who presented with dizziness, distal swelling of both lower limbs for 10 months and tingling and burning sensation in both feet for 9.5 months along with cold allodynia. Read More

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December 2016

Nerve conduction block in diabetic rats using high-intensity focused ultrasound for analgesic applications.

Br J Anaesth 2015 May 16;114(5):840-6. Epub 2015 Jan 16.

Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Zhunan, Taiwan

Background: Nerve conduction block using high-intensity focused ultrasound (HIFU) has been conducted with nerves of mixed fibres in normal animal models. This study tested the feasibility and safety of HIFU for sensory nerve conduction block in diabetic neuropathic nerves to determine its potential for pain relief.

Methods: Diabetes was induced in Sprague-Dawley rats using streptozotocin, and HIFU at 2. Read More

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