219 results match your criteria Nerve Block Sural


'SCALD-ED' Block: Superficial Cutaneous Anesthesia in a Lateral Leg Distribution within the Emergency Department - A Case Series.

J Emerg Med 2019 Jan 8. Epub 2019 Jan 8.

Department of Emergency Medicine, Rutgers New Jersey Medical School, Newark, New Jersey.

Background: In the midst of a nationwide opioid epidemic, focus has been placed on identifying and utilizing safe, effective opioid-free analgesic alternatives. Lower-extremity peripheral nerve blockades are common and often involve both motor and sensory anesthesia, resulting in leg weakness and ambulatory difficulty. The aim of this case report is to describe an ultrasound-guided peripheral nerve block technique (superficial cutaneous anesthesia in a lateral (leg) distribution within the emergency department ['SCALD-ED' block]) that provides motor-sparing, purely sensory anesthesia after a superficial injury to the lateral leg in patients presenting to the emergency department. Read More

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http://dx.doi.org/10.1016/j.jemermed.2018.12.005DOI Listing
January 2019
3 Reads

Anti-neurofascin autoantibody and demyelination.

Neurochem Int 2018 Dec 22. Epub 2018 Dec 22.

Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

Demyelination diseases involving the central and peripheral nervous systems are etiologically heterogeneous with both cell-mediated and humoral immunities playing pathogenic roles. Recently, autoantibodies against nodal and paranodal proteins, such as neurofascin186 (NF186), neurofascin155 (NF155), contactin-1 (CNTN1), contactin-associated protein 1 (CASPR1) and gliomedin, have been discovered in not only chronic demyelinating conditions, such as multiple sclerosis (MS) and chronic inflammatory demyelinating polyradiculoneuropathy, but also in acute demyelinating conditions, such as Guillain-Barré syndrome. Only a minority of these patients harbor anti-nodal/paranodal protein antibodies; however, these autoantibodies, especially IgG4 subclass autoantibodies to paranodal proteins, are associated with unique features and these conditions are collectively termed nodopathy or paranodopathy. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S01970186183043
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http://dx.doi.org/10.1016/j.neuint.2018.12.011DOI Listing
December 2018
7 Reads

Very Early Neurophysiological Study in Guillain-Barre Syndrome.

Eur Neurol 2018 22;80(1-2):100-105. Epub 2018 Oct 22.

Department of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an,

Purpose: The diagnosis of Guillain-Barre syndrome (GBS) in the very early stage may be challenging. Our aim was to report the neurophysiological abnormalities in GBS within 4 days of clinical onset. We expected that GBS will be diagnosed by the assistance of neurophysiological study in the very early stage. Read More

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https://www.karger.com/Article/FullText/494261
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http://dx.doi.org/10.1159/000494261DOI Listing
October 2018
12 Reads

Peripheral neuropathy in Tangier disease: A literature review and assessment.

J Peripher Nerv Syst 2018 Jun 8;23(2):88-98. Epub 2018 May 8.

Department of Molecular Medicine, Bakirkoy Dr. Sadi Konuk Research and Training Hospital, Istanbul, Turkey.

Tangier disease (TD) (OMIM#205400) is a rare cause of inherited metabolic neuropathies characterized by marked deficiency of high-density lipoproteins and accumulation of cholesterol esters in various tissue resulting from reverse cholesterol transport deficiency. We report a case of a patient with TD with multifocal demyelinating neuropathy with conduction block who presents with winging scapula, tongue, and asymmetric extremity weakness. We also present a review of all studies published from 1960 to 2017 regarding peripheral neuropathy in TD. Read More

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http://dx.doi.org/10.1111/jns.12265DOI Listing
June 2018
7 Reads

Guillain-Barré Syndrome.

Authors:
Peter D Donofrio

Continuum (Minneap Minn) 2017 Oct;23(5, Peripheral Nerve and Motor Neuron Disorders):1295-1309

Purpose Of Review: This article reviews the current state of Guillain-Barré syndrome (GBS), including its clinical presentation, evaluation, pathophysiology, and treatment.

Recent Findings: GBS is an acute/subacute-onset polyradiculoneuropathy typically presenting with sensory symptoms and weakness over several days, often leading to quadriparesis. Approximately 70% of patients report a recent preceding upper or lower respiratory tract infection or gastrointestinal illness. Read More

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http://Insights.ovid.com/crossref?an=00132979-201710000-0001
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http://dx.doi.org/10.1212/CON.0000000000000513DOI Listing
October 2017
6 Reads

Ultrasound-guided therapeutic injections for neural pathology about the foot and ankle: a 4 year retrospective review.

Skeletal Radiol 2017 Jun 16;46(6):795-803. Epub 2017 Mar 16.

Center for Musculoskeletal Care, New York University Langone Medical Center, New York, NY, USA.

Objective: To describe a 4-year clinical experience with ultrasound-guided therapeutic perineural injections of peripheral nerves about the foot and ankle.

Materials And Methods: Retrospective analysis of foot and ankle perineural injections performed between January 2012 and August 2016. Demographics, clinical indications, presence of structural pathology, immediate and interval pain relief, as well as complications were recorded. Read More

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http://dx.doi.org/10.1007/s00256-017-2624-7DOI Listing
June 2017
22 Reads

The mechanistic basis for photobiomodulation therapy of neuropathic pain by near infrared laser light.

Lasers Surg Med 2017 07 11;49(5):516-524. Epub 2017 Jan 11.

Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814.

Background And Objective: Various irradiances have been reported to be beneficial for the treatment of neuropathic pain with near infrared light. However, the mechanistic basis for the beneficial outcomes may vary based on the level of irradiance or fluence rate used. Using in vivo and in vitro experimental models, this study determined the mechanistic basis of photobiomodulation therapy (PBMT) for the treatment of neuropathic pain using a high irradiance. Read More

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http://dx.doi.org/10.1002/lsm.22628DOI Listing
July 2017
49 Reads

Dexmedetomidine Added to Local Anesthetic Mixture of Lidocaine and Ropivacaine Enhances Onset and Prolongs Duration of a Popliteal Approach to Sciatic Nerve Blockade.

Clin Ther 2017 01 10;39(1):89-97.e1. Epub 2016 Dec 10.

Department of Anaesthesiology, First Affiliated Hospital, Wenzhou Medical University, Zhejiang, China. Electronic address:

Purpose: A literature review of multiple clinical studies on mixing additives to improve pharmacologic limitation of local anesthetics during peripheral nerve blockade revealed inconsistency in success rates and various adverse effects. Animal research on dexmedetomidine as an adjuvant on the other hand has promising results, with evidence of minimum unwanted results. This randomized, double-blinded, contrastable observational study examined the efficacy of adding dexmedetomidine to a mixture of lidocaine plus ropivacaine during popliteal sciatic nerve blockade (PSNB). Read More

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http://dx.doi.org/10.1016/j.clinthera.2016.11.011DOI Listing
January 2017
14 Reads

[Clinical and electrophysiological characteristics and therapeutic analysis of 9 patients with Lewis-Sumner syndrome].

Zhonghua Yi Xue Za Zhi 2016 Mar;96(11):859-62

Department of Neurology, Peking University Third Hospital, Beijing 100191, China.

Objective: To investigate the clinical characteristics, electrophysiological findings and treatment response of Lewis-Sumner syndrome (LSS).

Methods: Data of nine patients with LSS, who were diagnosed and treated from May 2008 to August 2014 in Department of Neurology, Peking University Third Hospital, were analyzed retrospectively, including clinical features, electrophysiological studies, pathological characteristics, therapy and follow up.

Results: The nine cases included seven males and two females, with the average age being 29 years old (18-64 years old). Read More

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http://dx.doi.org/10.3760/cma.j.issn.0376-2491.2016.11.007DOI Listing
March 2016
9 Reads

Workup and Management of Persistent Neuralgia following Nerve Block.

Case Rep Anesthesiol 2016 19;2016:9863492. Epub 2016 Jan 19.

University of California San Francisco School of Medicine, San Francisco, CA, USA.

Neurological injuries following peripheral nerve blocks are a relatively rare yet potentially devastating complication depending on the type of lesion, affected extremity, and duration of symptoms. Medical management continues to be the treatment modality of choice with multimodal nonopioid analgesics as the cornerstone of this therapy. We report the case of a 28-year-old man who developed a clinical common peroneal and lateral sural cutaneous neuropathy following an uncomplicated popliteal sciatic nerve block. Read More

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http://dx.doi.org/10.1155/2016/9863492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4745965PMC
February 2016
3 Reads

N-hexane neuropathy with vertigo and cold allodynia in a silk screen printer: A case study.

Int J Occup Med Environ Health 2015 ;28(5):915-9

Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India (Department of Neurology).

N-hexane neuropathy is an occupational disease caused by exposure to n-hexane, which is used as a solvent in silk screen printing. Here, we describe a 35-year-old man, a silk screen printer by profession, who presented with dizziness, distal swelling of both lower limbs for 10 months and tingling and burning sensation in both feet for 9.5 months along with cold allodynia. Read More

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http://ijomeh.eu/pdf-58502-2947?filename=N-hexane%20neuropat
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http://www.journalssystem.com/ijomeh/N-hexane-neuropathy-wit
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http://dx.doi.org/10.13075/ijomeh.1896.00327DOI Listing
December 2016
2 Reads

Nerve conduction block in diabetic rats using high-intensity focused ultrasound for analgesic applications.

Br J Anaesth 2015 May 16;114(5):840-6. Epub 2015 Jan 16.

Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Zhunan, Taiwan

Background: Nerve conduction block using high-intensity focused ultrasound (HIFU) has been conducted with nerves of mixed fibres in normal animal models. This study tested the feasibility and safety of HIFU for sensory nerve conduction block in diabetic neuropathic nerves to determine its potential for pain relief.

Methods: Diabetes was induced in Sprague-Dawley rats using streptozotocin, and HIFU at 2. Read More

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http://bja.oxfordjournals.org/content/early/2015/01/15/bja.a
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http://bja.oxfordjournals.org/lookup/doi/10.1093/bja/aeu443
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http://dx.doi.org/10.1093/bja/aeu443DOI Listing
May 2015
3 Reads

Leprosy neuropathy evaluated by NCS is independent of the patient's infectious state.

Clin Neurol Neurosurg 2015 Apr 12;131:5-10. Epub 2015 Jan 12.

Leprosy Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, RJ, Brazil.

Introduction: Leprosy causes nerve injury, which mimics clinical and neurophysiological conditions, rendering it an excellent model of peripheral neuropathy.

Methods: A retrospective study including 822 nerve conduction studies (NCS) of 509 patients was developed to appraise the electrophysiological pattern of leprosy neuropathy. NCS of motor and sensory nerves performed before, during, and after multidrug therapy (MDT) were analyzed. Read More

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http://dx.doi.org/10.1016/j.clineuro.2015.01.008DOI Listing
April 2015
3 Reads

Contribution of the sural nerve to postural stability and cutaneous sensation of the lower limb.

Foot Ankle Int 2015 Apr 19;36(4):450-6. Epub 2014 Dec 19.

Department of Podiatry, Faculty of Health Sciences, La Trobe University, Bundoora, Victoria, Australia

Background: The sural nerve is a cutaneous nerve of the lower limb that innervates the posterolateral aspect of the lower leg, ankle, and foot. Considering this pattern, it is plausible that it contributes to the maintenance of postural stability. However, the implications of sensory loss following sural nerve injury have yet to be thoroughly investigated. Read More

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http://dx.doi.org/10.1177/1071100714560398DOI Listing
April 2015
9 Reads

High-intensity focused ultrasound attenuates neural responses of sciatic nerves isolated from normal or neuropathic rats.

Ultrasound Med Biol 2015 Jan 15;41(1):132-42. Epub 2014 Nov 15.

Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Zhunan, Taiwan. Electronic address:

Patients with diabetic neuropathy often have neuropathic pain. The purpose of our work was to investigate the effects of high-intensity focused ultrasound (HIFU) on the conduction block of normal and neuropathic nerves for soothing pain. Adult male Sprague-Dawley rats were used, and diabetes was induced by streptozotocin injection. Read More

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http://dx.doi.org/10.1016/j.ultrasmedbio.2014.08.014DOI Listing
January 2015
4 Reads

Comparison of electrophysiological findings in axonal and demyelinating Guillain-Barre syndrome.

Iran J Neurol 2014 Jul;13(3):138-43

Department of Neurology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Background: Incidence and predominant subtype of Guillain-Barre syndrome (GBS) differs geographically. Electrophysiology has an important role in early diagnosis and prediction of prognosis. This study is conducted to determine the frequent subtype of GBS in a large group of patients in Iran and compare nerve conduction studies in axonal and demyelinating forms of GBS. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4240930PMC
July 2014
21 Reads

A prospective, randomized comparison between single- and multiple-injection techniques for ultrasound-guided subgluteal sciatic nerve block.

Anesth Analg 2014 Dec;119(6):1442-8

From the Department of Anesthesiology, Shimane University School of Medicine, Izumo City, Japan.

Background: It is believed that local anesthetic injected to obtain circumferential spread around nerves produces a more rapid onset and successful blockade after some ultrasound-guided peripheral nerve blocks. However, evidence demonstrating this point is limited only to the popliteal sciatic nerve block, which is relatively easy to perform by via a high-frequency linear transducer. In the present study, we tested the hypothesis that multiple injections of local anesthetic to make circumferential spread would improve the rate of sensory and motor blocks compared with a single-injection technique for ultrasound-guided subgluteal sciatic nerve block, which is considered a relatively difficult block conducted with a low-frequency, curved-array transducer. Read More

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http://pdfs.journals.lww.com/anesthesia-analgesia/2014/12000
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1213/ANE.0000000000000462DOI Listing
December 2014
11 Reads

The effect of a combination of gabapentin and donepezil in an experimental pain model in healthy volunteers: Results of a randomized controlled trial.

Pain 2014 Dec 10;155(12):2510-6. Epub 2014 Sep 10.

GlaxoSmithKline, Stevenage, UK. Electronic address:

This double-blind, placebo-controlled, 3-period cross-over, 4-treatment option, incomplete block study (ClinicalTrials.gov number NCT01485185), with an adaptive design for sample size re-estimation, was designed to evaluate gabapentin plus donepezil in an established experimental model of electrical hyperalgesia. Thirty healthy male subjects aged 18-55 years were randomized to receive gabapentin 900 mg or gabapentin 900 mg+donepezil 5mg for 2 of the 3 treatment periods, with 50% of subjects randomized to receive placebo (negative control) and 50% to gabapentin 1800 mg (positive control) for the remaining period. Read More

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1016/j.pain.2014.09.003DOI Listing
December 2014
5 Reads

[Neurophysiologic studies of POEMS syndrome and its related diseases].

Zhonghua Yi Xue Za Zhi 2014 Feb;94(5):356-8

Department of Neurology, Peking University Third Hospital, Beijing 100191, China. Email:

Objective: To explore the electrophysiological characteristics of polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes (POEMS) syndrome and its related diseases.

Methods: The electrophysiological characteristics were analyzed retrospectively from June 2000 to June 2013 in patients with POEMS syndrome, monoclonal gammopathy of undetermined significance (MGUS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Electromyography and nerve conduction examinations of median, ulnar, tibial, peroneal and sural nerves were performed. Read More

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February 2014
1 Read

Neural mechanisms underlying pain's ability to reorient attention: evidence for sensitization of somatic threat detectors.

Authors:
Robert Dowman

Cogn Affect Behav Neurosci 2014 Jun;14(2):805-17

Department of Psychology, Clarkson University, 8 Clarkson Ave, Potsdam, NY, 13699-5825, USA,

Pain typically signals damage to the body, and as such can be perceived as threatening and can elicit a strong emotional response. This ecological significance undoubtedly underlies pain's well-known ability to demand attention. However, the neural mechanisms underlying this ability are poorly understood. Read More

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http://dx.doi.org/10.3758/s13415-013-0233-zDOI Listing
June 2014
1 Read

Morbidity and complications following percutaneous calcaneal autograft bone harvest.

Foot Ankle Int 2014 Jan 6;35(1):30-7. Epub 2013 Dec 6.

Hospital for Special Surgery, New York, USA.

Background: Autogenous bone grafting is commonly used as an adjuvant in foot and ankle procedures. The iliac crest and tibia are common sources of autogenous bone graft but require a separate operative site and have been reported to have significant morbidity including pain, fractures, and prolonged hospitalization. Bone grafting from the posterolateral calcaneus offers advantages such as a single operative field, ability to be done under an ankle block, and a theoretical low complication rate. Read More

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http://dx.doi.org/10.1177/1071100713511806DOI Listing
January 2014
1 Read

Hereditary neuropathy with liability to pressure palsy: a recurrent and bilateral foot drop case report.

Case Rep Pediatr 2013 23;2013:230541. Epub 2013 Oct 23.

Department of Pediatrics, Centro Hospitalar do Alto Ave, Hospital de Guimarães, 4835-044 Guimarães, Portugal ; Department of Pediatrics, Centro Hospitalar de São João, Alameda Prof. Hernâni Monteiro, 4200-319 Porto, Portugal.

Hereditary neuropathy with liability to pressure palsy is characterized by acute, painless, recurrent mononeuropathies secondary to minor trauma or compression. A 16-year-old boy had the first episode of right foot drop after minor motorcycle accident. Electromyography revealed conduction block and slowing velocity conduction of the right deep peroneal nerve at the fibular head. Read More

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http://www.dnalab.cz/publikace/CMT/HNPP_Paprocka_Folia%20Neu
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http://www.hindawi.com/journals/cripe/2013/230541/
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http://dx.doi.org/10.1155/2013/230541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3819892PMC
November 2013
8 Reads

[Vasculitic peripheral neuropathy].

Authors:
Yasushi Oya

Brain Nerve 2013 Nov;65(11):1299-309

Department of Neurology, National Center Hospital, National Center of Neurology and Psychiatry.

The typical clinical manifestation of vasculitic peripheral neuropathy is sensory-dominant multiple mononeuropathy, although it can progress to distal-dominant sensorimotor polyneuropathy. It is painful in most cases. Peripheral nerves may be the most prone to produce symptoms of the vasculitis. Read More

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November 2013
1 Read

Proximally based sural adipose-cutaneous/scar flap in elimination of ulcerous scar soft-tissue defect over the achilles tendon and posterior heel region: a new approach.

J Burn Care Res 2014 May-Jun;35(3):e143-50

From the Department of Reconstructive and Plastic Surgery, A.V. Vishnevsky Institute of Surgery of the Russian Academy of Medical Sciences, Moscow, Russia.

Scar ulcers that spread over the Achilles tendon and posterior heel disturb patients by causing pain, impeding hygiene, and creating difficulty in finding appropriate shoe wear. As this region undergoes pressure, effective reconstruction is based on the flap use. The most popular flaps currently used are distally based sural fasciocutaneous flap, calcaneal artery skin flap, and free flaps. Read More

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http://dx.doi.org/10.1097/BCR.0b013e3182a2a74fDOI Listing
January 2015
3 Reads

The sensate fibula osteocutaneous flap: neurosomal anatomy.

J Plast Reconstr Aesthet Surg 2013 Dec 30;66(12):1688-94. Epub 2013 Jul 30.

Harbor-UCLA Medical Center and the David Geffen School of Medicine at UCLA, USA. Electronic address:

Background: Rapid return of oral sensation enhances quality of life following oromandibular reconstruction. For predictable reinnervation of flaps, a detailed knowledge of their nerve supply is required. This study was designed to investigate the cutaneous nerve supply of the fibula osteocutaneous flap. Read More

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http://dx.doi.org/10.1016/j.bjps.2013.07.018DOI Listing
December 2013
21 Reads

Sensorimotor polyneuropathy in patients with SMA type-1: electroneuromyographic findings.

Muscle Nerve 2013 Jul 30;48(1):117-21. Epub 2013 Apr 30.

Akdeniz University Hospital, H Block, Department of Child Neurology, Antalya, Turkey.

Introduction: Generally, spinal muscular atrophy (SMA) is believed to be a pure motor neuron disease. We retrospectively evaluated our electrodiagnostic findings in SMA type 1 patients to demonstrate co-existence of sensorimotor neuropathies.

Methods: Electroneuromyographic (ENMG) studies in 15 patients (11 boys, 4 girls) were reviewed independently by 2 neurophysiologists. Read More

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http://dx.doi.org/10.1002/mus.23722DOI Listing
July 2013
3 Reads

Pathophysiology of HNPP explored using axonal excitability.

J Neurol Neurosurg Psychiatry 2013 Jul 16;84(7):806-12. Epub 2013 Feb 16.

Department of Neurology, Institute of Clinical Neuroscience, Royal Prince Alfred Hospital, and University of Sydney, Level 2, Medical Foundation Building, 92 Parramatta Road, Camperdown, Sydney, NSW 2050, Australia.

Objective: Hereditary liability to pressure palsies (HNPP) is an autosomal dominant disorder of myelination resulting in susceptibility to pressure palsies from compression or stretching of peripheral nerves.

Patients And Methods: This study examined axonal excitability at two sites (one distal and one proximal) in five patients with biopsy and genetically proven HNPP to understand the pathophysiology of the disease. Comparisons were made with age-matched control subjects as well as five Charcot-Marie-Tooth type 1A patients to contrast the findings and explain the different phenotypes of diseases affecting the same gene. Read More

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http://dx.doi.org/10.1136/jnnp-2012-304576DOI Listing
July 2013
1 Read

Block of peripheral pain response by high-frequency sinusoidal stimulation.

Neuromodulation 2013 Jul-Aug;16(4):312-7; discussion 317. Epub 2013 Jan 7.

Department of Biomedical Engineering, Neural Engineering Center, Case Western Reserve University, Cleveland, OH, USA.

Objectives: Pain due to peripheral neuropathy is extremely difficult to treat as drugs often become less and less effective over the course of a patient's life. In order to augment such treatments, electrical stimulation has become relatively common, in the form of transcutaneous electrical nerve stimulation, peripheral nerve stimulation, and spinal cord stimulation. Unfortunately, these treatments are only effective in a subset of chronic pain patients. Read More

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http://dx.doi.org/10.1111/ner.12011DOI Listing
April 2014
2 Reads

Expectations modulate heterotopic noxious counter-stimulation analgesia.

J Pain 2013 Feb 20;14(2):114-25. Epub 2012 Dec 20.

Department of Psychology, Université de Montréal, Montréal, QC, Canada.

Unlabelled: The present study examined the contribution of expectations to analgesia induced by heterotopic noxious counter-stimulation (HNCS) in healthy volunteers assigned to a control group or 1 of 3 experimental groups in which expectations were either assessed (a priori expectations) or manipulated using suggestions (hyperalgesia and analgesia). Acute shock-pain, the nociceptive flexion reflex (RIII-reflex), and shock-related anxiety were measured in response to electrical stimulations of the right sural nerve in the baseline, HNCS, and recovery periods. Counter-stimulation was applied on the contralateral forearm using a flexible cold pack. Read More

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http://dx.doi.org/10.1016/j.jpain.2012.10.006DOI Listing
February 2013
3 Reads

Frequency-modulated electromagnetic neural stimulation (FREMS) as a treatment for symptomatic diabetic neuropathy: results from a double-blind, randomised, multicentre, long-term, placebo-controlled clinical trial.

Diabetologia 2013 Mar 13;56(3):467-75. Epub 2012 Dec 13.

Diabetes & Endocrinology Unit, Department of Internal Medicine, San Raffaele Hospital and San Raffaele Vita Salute University, Via Olgettina 60, 20132 Milan, Italy.

Aims/hypothesis: The aim was to evaluate the efficacy and safety of transcutaneous frequency-modulated electromagnetic neural stimulation (frequency rhythmic electrical modulation system, FREMS) as a treatment for symptomatic peripheral neuropathy in patients with diabetes mellitus.

Methods: This was a double-blind, randomised, multicentre, parallel-group study of three series, each of ten treatment sessions of FREMS or placebo administered within 3 weeks, 3 months apart, with an overall follow-up of about 51 weeks. The primary endpoint was the change in nerve conduction velocity (NCV) of deep peroneal, tibial and sural nerves. Read More

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http://link.springer.com/content/pdf/10.1007%2Fs00125-005-17
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http://link.springer.com/10.1007/s00125-012-2795-7
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http://dx.doi.org/10.1007/s00125-012-2795-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563945PMC
March 2013
3 Reads

Tetrodotoxin-resistant fibres and spinal Fos expression: differences between input from muscle and skin.

Exp Brain Res 2013 Feb 18;224(4):571-80. Epub 2012 Nov 18.

Department of General Internal and Psychosomatic Medicine, Ruprecht-Karls-University Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

Nociceptive information from muscle and skin is differently processed at many levels of the central nervous system. In most articles on this issue, noxious stimuli were used that also excited non-nociceptive receptors. The effects of a pure nociceptive input from muscle or skin on spinal neurones are largely unknown. Read More

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http://link.springer.com/10.1007/s00221-012-3337-8
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http://dx.doi.org/10.1007/s00221-012-3337-8DOI Listing
February 2013
4 Reads

Acute onset distal symmetrical vasculitic polyneuropathy associated with acute hepatitis B.

J Clin Neurosci 2013 Feb 17;20(2):331-2. Epub 2012 Nov 17.

Department of Neurology, Room 511, Academic Block, GB Pant Hospital, JLN Marg, New Delhi-2 110002, India.

Hepatitis B can have varied extrahepatic manifestations involving the skin, renal, haematological and nervous systems. Neurological manifestations in hepatitis B may take the form of Guillain-Barré syndrome and secondary systemic vasculitis-related mononeuritis multiplex. The clinical course of hepatitis B-related, vasculitis-related neuropathy is usually subacute to chronic and clinical evolution is relatively benign. Read More

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http://dx.doi.org/10.1016/j.jocn.2012.03.029DOI Listing
February 2013
3 Reads

The significance of tibial and common peroneal nerves in nerve blocks.

Surg Radiol Anat 2013 Apr 27;35(3):211-5. Epub 2012 Sep 27.

Department of Anatomy, College of Medicine, The Konyang University of Korea, Daejeon, Korea.

Purpose: The aim of this study was to elucidate the anatomical location of tibial nerve (TN) and common peroneal nerve (CPN) in the popliteal crease for specific nerve block.

Methods: Fifty fresh specimens from 27 adult Korean cadavers (16 males and 11 females, age 35-87 years) were investigated. Five of the 27 cadavers were used to determine the depths of nerves in cross-section. Read More

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http://dx.doi.org/10.1007/s00276-012-1025-9DOI Listing
April 2013
6 Reads

Ultrasound-guided ankle block for forefoot surgery: the contribution of the saphenous nerve.

Reg Anesth Pain Med 2012 Sep-Oct;37(5):554-7

Department of Anesthesiology, Hospital Clínic, Barcelona, Spain.

Background: Ankle blocks typically include the block of 5 nerves, the 4 branches that trace their origin back to the sciatic nerve plus the saphenous nerve (SaN). The sensory area of the SaN in the foot is variable. Based on our clinical experience, we decided to study the sensory distribution of the SaN in the foot and determine whether the block of this nerve is necessary as a component of an ultrasound-guided ankle block for bunion surgery. Read More

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http://dx.doi.org/10.1097/AAP.0b013e3182611483DOI Listing
June 2013
14 Reads

Top-down attentional modulation of analgesia induced by heterotopic noxious counterstimulation.

Pain 2012 Aug 18;153(8):1755-62. Epub 2012 Jun 18.

Department of Psychology, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada G9A 5H7.

Heterotopic noxious counterstimulation (HNCS) by the application of a sustained noxious stimulus has been shown to inhibit nociceptive processes and decrease pain induced by a competing noxious stimulus. However, it is still not clear how attentional processes contribute to these effects. The main objective of this study was to compare the analgesic effects of HNCS in 2 sessions during which top-down attention was manipulated. Read More

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http://dx.doi.org/10.1016/j.pain.2012.05.019DOI Listing
August 2012
3 Reads

[Case report of transthyretin Val30Met familial amyloid polyneuropathy presenting hydrocephalus].

Rinsho Shinkeigaku 2012 ;52(4):257-60

Department of Neurology, Kyoto University Hospital.

A 70-year-old man was admitted to our hospital with visual loss, dysesthesia, gait disturbance, and urinary retention. A pacemaker was implanted 1 year ago for atrioventricular conduction block. Neurologic examination revealed mild cognitive impairment, near blindness with vitreous opacity, diffuse muscle weakness, loss of all sensory modalities with areflexia, and orthostatic hypotension. Read More

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March 2013
3 Reads

Neuropathic complications after 157 procedures of continuous popliteal nerve block for hallux valgus surgery. A retrospective study.

Orthop Traumatol Surg Res 2012 May 28;98(3):327-33. Epub 2012 Mar 28.

Neurology department, Desgenettes military teaching hospital, 69275 Lyon, France.

Background: Continuous peripheral nerve block (CPNB), in particular at the popliteal fossa, is widely used in orthopedic surgery, allowing good postoperative analgesia. Possible neuropathic complications, however, remain poorly known.

Objective: To review the characteristics of peripheral neuropathy (PN) after sciatic CPNB at the popliteal fossa, estimating prevalence, severity, evolution and possible risk factors, especially those relating to the procedure. Read More

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http://dx.doi.org/10.1016/j.otsr.2011.11.004DOI Listing
May 2012
10 Reads

Uniform demyelination and more severe axonal loss distinguish POEMS syndrome from CIDP.

J Neurol Neurosurg Psychiatry 2012 May 6;83(5):480-6. Epub 2012 Mar 6.

Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

Objective: POEMS syndrome (the acronym reflects the common features: Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal protein and Skin changes) is a paraneoplastic disorder with a 'demyelinating' peripheral neuropathy that is often mistaken for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). The nerve conduction study (NCS) and electromyography (EMG) attributes that might differentiate POEMS from CIDP and lead to earlier therapeutic intervention were explored.

Methods: NCS/EMG of POEMS patients identified through retrospective review from 1960 to 2007 were compared with matched CIDP controls. Read More

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http://dx.doi.org/10.1136/jnnp-2011-301472DOI Listing
May 2012
10 Reads

Ultrasound-guided Lateral Femoral Cutaneous Nerve Block in Meralgia Paresthetica.

Korean J Pain 2011 Jun 3;24(2):115-8. Epub 2011 Jun 3.

Department of Anesthesiology and Pain Medicine, Daegu Fatima Hospital, Daegu, Korea.

Meralgia paresthetica is a rarely encountered sensory mononeuropathy characterized by paresthesia, pain or sensory impairment along the distribution of the lateral femoral cutaneous nerve (LFCN) caused by entrapment or compression of the nerve as it crossed the anterior superior iliac spine and runs beneath the inguinal ligament. There is great variability regarding the area where the nerve pierces the inguinal ligament, which makes it difficult to perform blind anesthetic blocks. Ultrasound has developed into a powerful tool for the visualization of peripheral nerves including very small nerves such as accessory and sural nerves. Read More

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http://dx.doi.org/10.3344/kjp.2011.24.2.115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3111560PMC
June 2011
16 Reads

Effects of perineural tramadol on nerve conduction of sural nerve.

Agri 2011 Apr;23(2):51-6

Department of Physical Medicine and Rehabilitation, Gazi University Faculty of Medicine, Ankara, Turkey.

Objectives: The aim of this study was to investigate whether tramadol had a dose-dependent blocking effect on nerve conduction when administered perineurally to the sural nerve of healthy volunteers.

Methods: Twenty-four informed healthy subjects were randomized into four equal groups [Saline (placebo), 0.5% tramadol, 1% tramadol and 1. Read More

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April 2011
2 Reads

Pulsed radiofrequency of the sural nerve for the treatment of chronic ankle pain.

Authors:
Lyudmil Todorov

Pain Physician 2011 May-Jun;14(3):301-4

Memorial Hospital of Rhode Island, Pawtucket, RI, USA.

Background: The application of radiofrequency (RF) has been successfully used in the treatment of chronic pain conditions, including facet arthropathy, sacroiliac joint pain, groin pain, radicular pain, cervicogenic headaches, and phantom limb pain. Due to the neurodestructive effect of continuous RF ablation and possible deafferentation sequelae, only pulsed radiofrequency (PRF) has been applied to peripheral sensory nerves. There are no previous reports of successful PRF application to the sural nerve. Read More

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April 2012
2 Reads

Ankle block implemented through two skin punctures.

Foot Ankle Int 2010 Jul;31(7):619-23

Motol University Hospital, 1st Orthopaedic Clinic, V Uvalu 84, Prague 5, 15006, Czech Republic.

Background: Recently, peripheral nerve blocks have increasingly been used in orthopedic surgery. The foot block is an alternative for anesthesia in cases of forefoot and midfoot operations. We propose a modification of the block technique due to potential difficulties concerning the tibial nerve. Read More

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http://journals.sagepub.com/doi/10.3113/FAI.2010.0619
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http://dx.doi.org/10.3113/FAI.2010.0619DOI Listing
July 2010
5 Reads

Electrophysiological sensory demyelination in typical chronic inflammatory demyelinating polyneuropathy.

Eur J Neurol 2010 Jul 10;17(7):939-44. Epub 2010 Feb 10.

Department of Neurology, Neuromuscular Clinic, University Hospitals of Leicester, Leicester, UK.

Background: The presence of electrophysiological demyelination of sensory nerves is not routinely assessed in the evaluation of suspected chronic inflammatory demyelinating polyneuropathy (CIDP). Whether this can be useful is unknown.

Methods: We compared, using surface recording techniques, in 19 patients with typical CIDP and 26 controls with distal large fibre sensory axonal neuropathy, the forearm median sensory conductions, sensory nerve action potential (SNAP) amplitudes and durations and sensory nerve conduction velocities (SNCVs) of median, radial and sural nerves. Read More

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http://dx.doi.org/10.1111/j.1468-1331.2010.02953.xDOI Listing
July 2010
2 Reads

Neurophysiological findings in patients 1 year after snake bite induced neurotoxicity in Sri Lanka.

Trans R Soc Trop Med Hyg 2010 May 22;104(5):351-6. Epub 2010 Jan 22.

Tropical and Infectious Diseases Unit, Royal Liverpool University Hospital, Liverpool L7 8XP, UK.

Snake bite causes significant morbidity and mortality in Sri Lanka. Snake venoms contain neurotoxins that block neuromuscular junction transmission. Presynaptic neurotoxicity most commonly causes destruction of nerve terminals with recovery by regrowth, whilst postsynaptic neurotoxicity usually involves competition at the acetylcholine receptor. Read More

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http://dx.doi.org/10.1016/j.trstmh.2009.12.003DOI Listing
May 2010
2 Reads

Sensory testing of distal sural and posterior tibial nerves provides early prediction of surgical anesthesia after single-injection infragluteal-parabiceps sciatic nerve block.

Anesth Analg 2010 Mar 10;110(3):951-7. Epub 2009 Dec 10.

Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.

Background: Surgical anesthesia for reconstructive ankle surgery requires sensory and motor block of all the terminal nerve distributions of the sciatic nerve. In this prospective observational study, we investigated the value of sensory and motor testing of the foot, after local anesthetic injection, for predicting complete sciatic nerve blockade and the duration of testing required for identifying incomplete anesthesia.

Methods: Sciatic nerve blocks (n = 180) using the infragluteal-parabiceps approach were performed in patients undergoing reconstructive ankle surgery. Read More

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http://dx.doi.org/10.1213/ANE.0b013e3181ca134bDOI Listing
March 2010
14 Reads

Effects of unpredictable stimulation on pain and nociception across the cardiac cycle.

Pain 2009 Dec 18;147(1-3):84-90. Epub 2009 Sep 18.

International Centre for Health & Exercise Research, University of Birmingham, Birmingham, UK.

Previous research has demonstrated that the nociceptive flexion reflex (NFR) and pain-related evoked potentials are reduced in amplitude when elicited during the middle of the cardiac cycle. Despite these findings, suggesting a baroreceptor mechanism of antinociception during systole, pain intensity ratings reported in these studies were not modulated across the cardiac cycle. This discrepancy between the neurophysiological correlates of pain and its subjective experience was the focus of the current study that used a mixed block design to assess the effects of natural arterial baroreceptor activity on both the NFR and pain intensity and unpleasantness reports. Read More

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http://dx.doi.org/10.1016/j.pain.2009.08.016DOI Listing
December 2009
2 Reads

Intraneural perineurioma.

J Clin Neurosci 2009 Dec 17;16(12):1633-6. Epub 2009 Sep 17.

Department of Anatomical Pathology, Section of Neuropathology, Royal Perth Hospital, 2nd Floor North Block, Wellington Street Campus, Perth, Western Australia 6847, Australia.

Intraneural perineurioma is a rare tumour that affects peripheral nerves and, based on its histological features, may be confused with hereditary motor and sensory neuropathies. Detailed neuropathology, including immunoperoxidase stains and electron microscopy, is vital to distinguish these conditions. We report two patients with intraneural perineurioma that demonstrate salient features of this tumour. Read More

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http://dx.doi.org/10.1016/j.jocn.2009.02.013DOI Listing
December 2009
2 Reads