231 results match your criteria Nerve Block Sural


Am J Phys Med Rehabil 2021 Apr 14. Epub 2021 Apr 14.

EMG Service, Local Health Unit Toscana Sud Est, Siena, Italy Department of Medical, Surgical and Neurological Sciences, University of Siena, Italy.

Objective: To demonstrate abnormalities of motor conduction of the tibial nerve across the tarsal tunnel (TT) in type 2 diabetes.

Design: 124 consecutive patients (mean age 66.6 years, 62. Read More

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Utility of Neuropathy Screening for Wild-Type Transthyretin Amyloidosis Patients.

Can J Neurol Sci 2020 Dec 21:1-9. Epub 2020 Dec 21.

Division of Cardiology, Department of Cardiac Sciences, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.

Background: Wild-type transthyretin amyloidosis (wtATTR) is an important cause of heart failure (HF); however, the prevalence and clinical significance of neurologic complications remains uncertain.

Methods: This analysis reports findings from a single-centre experience of routine neuropathy screening at the time of wtATTR diagnosis by nerve conduction studies and neurologist assessment, compared with age-matched controls.

Results: Forty-one wtATTR patients were included, 39 (95%) males, mean age 78. Read More

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December 2020

Dissociation of axo-glial junction in anti-neurofascin 155 chronic inflammatory demyelinating polyneuropathy.

Clin Neuropathol 2021 Mar-Apr;40(2):87-92

Aims: A subset of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is characterized by the presence of anti-neurofascin 155 (anti-NF155) autoantibodies. In this paper, we investigated an anti-NF155 CIDP patient via clinical, electrophysiological, and neuropathological tests.

Materials And Methods: The patient was a 15-year-old Chinese boy affected by distal limb weakness and tremor for a 6-month period. Read More

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February 2021

Outcome After Modified Grice-Green Procedure (SAMBB) for Arthritic Acquired Adult Flatfoot.

Foot Ankle Int 2020 Nov 11;41(11):1404-1410. Epub 2020 Aug 11.

I Clinic of Orthopaedics and Traumatology, Istituto Ortopedico Rizzoli, Bologna, Italy.

Background: Adult acquired flatfoot deformity is a well-known and recognized cause of pain and disability. The purpose of this retrospective study was to describe radiographic and clinical outcomes of the modified mini bone block distraction subtalar arthrodesis (SAMBB) in adult patients affected by adult flatfoot with subtalar joint osteoarthritis at a midterm mean follow-up.

Methods: A retrospective review of our database identified patients. Read More

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November 2020

Nerve Blocks: Part II. Lower Extremity.

Am Fam Physician 2020 06;101(11):669-679

Uniformed Services University of the Health Sciences, Bethesda, MD, USA.

Family physicians use anesthesia to provide diagnostic and procedural analgesia for conditions such as neuropathies, fracture reduction, foreign body removals, and complex wound management. Local infiltration of anesthetics is commonly used in this setting because of the ease of use, safety, and effectiveness of the procedure. Nerve blocks are a specific regional anesthesia technique that blocks nerve function distal to the injection site. Read More

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Pmp22 super-enhancer deletion causes tomacula formation and conduction block in peripheral nerves.

Hum Mol Genet 2020 06;29(10):1689-1699

Waisman Center, University of Wisconsin-Madison, Madison, WI 53705, USA.

Copy number variation of the peripheral nerve myelin gene Peripheral Myelin Protein 22 (PMP22) causes multiple forms of inherited peripheral neuropathy. The duplication of a 1.4 Mb segment surrounding this gene in chromosome 17p12 (c17p12) causes the most common form of Charcot-Marie-Tooth disease type 1A, whereas the reciprocal deletion of this gene causes a separate neuropathy termed hereditary neuropathy with liability to pressure palsies (HNPP). Read More

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Habituation of the Interlimb Reflex (ILR) Over the Biceps Brachii Muscle After Electrical Stimuli Over the Sural Nerve.

Front Neurosci 2019 23;13:1130. Epub 2019 Oct 23.

Department of Neurology, Martin Luther University of Halle-Wittenberg, Halle (Saale), Germany.

Up to now relatively little is known about interlimb reflexes (ILR). Especially it is not well known whether ILR may habituate or not to subsequent stimuli. The main aim of the present investigation was to explore the short term habituation behavior of ILR. Read More

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October 2019

An Anatomic and Clinical Study of the Innervation of the Dorsal Midfoot Capsule.

Foot Ankle Int 2019 Oct 23;40(10):1209-1213. Epub 2019 Jul 23.

Department of Orthopedic Surgery, Medical College of Wisconsin, Milwaukee, WI, USA.

Background: Dorsal pain from osteoarthritic midfoot joints is thought to be relayed by branches of the medial and lateral plantar, sural, saphenous, and deep peroneal nerves (DPN). However, there is no consensus on the actual number or pathways of the nervous branches for midfoot joint capsular innervation. This study examined the DPN's terminal branches at the midfoot joint capsules through anatomic dissection and confirmation of their significance in a clinical case series of patients with midfoot pain relief after DPN block. Read More

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October 2019

Ultrasound-guided ankle block. History revisited.

Best Pract Res Clin Anaesthesiol 2019 Mar 7;33(1):79-93. Epub 2019 May 7.

Department of Anaesthesiology, University Hospitals of the KU Leuven, Herestraat 49, 3000, Leuven, Belgium.

Following forefoot surgery, compared to the traditional multimodal approach, regional anesthesia and analgesia provides high quality pain relief, decreases opioids consumption and leads to very high satisfaction scores. Traditional regional techniques relied either on wound infiltration, landmark technique ankle blocks or popliteal sciatic nerve block. Numerous anatomic variations of the different nerves might lead to failure following a blind technique. Read More

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Sagittal Resection Osteotomy With Bone Block Distraction Subtalar Fusion for Treatment of Malunited Calcaneal Fractures.

J Foot Ankle Surg 2019 Jul 1;58(4):739-747. Epub 2019 May 1.

Orthopedic Resident, Elhadara University Hospital, Elhadara, Lambrouzou, Alexandria, Egypt.

The aim of this prospective study was to evaluate the results of combined lateral sagittal resection osteotomy with subtalar distraction fusion in heels with painful malunion of the os calcis. This case series included 22 patients (23 feet). The mean age of the patients was 37. Read More

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Randomized Controlled Trial of Physical Exercise in Diabetic Veterans With Length-Dependent Distal Symmetric Polyneuropathy.

Front Neurosci 2019 11;13:51. Epub 2019 Feb 11.

Research Service, Department of Veterans Affairs, Edward Hines Jr. VA Hospital, Hines, IL, United States.

Physical exercise is an essential adjunct to the management of patients with type 2 diabetes mellitus. Therapeutic interventions that improve blood flow to peripheral nerves, such as exercise, may slow the progression of neuropathy in the diabetic patient. This randomized clinical trial was conducted to determine whether a structured program of aerobic, isokinetic strength, or the combination of aerobic-isokinetic strength exercise intervention alters peripheral nerve function in glycemic-controlled diabetic patients with advanced length-dependent distal symmetric polyneuropathy. Read More

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February 2019

Injection-related iatrogenic peripheral nerve injuries: Surgical experience of 354 operated cases.

Neurol India 2019 Jan-Feb;67(Supplement):S82-S91

Department of Neurosurgery, PD Hinduja Hospital, Mumbai, Maharashtra, India.

Objective: A retrospective analysis of surgically treated 354 cases of injection-related iatrogenic peripheral nerve injuries was performed. The purpose of this clinical study was to present our experience in the management of various types of injection-related peripheral nerve injuries and discuss various issues that are associated with this subset of peripheral nerve injuries.

Methods: Over a 17-year period, 354 cases of injection-related iatrogenic peripheral nerve injuries were managed surgically at the Department of Neurosurgery at P. Read More

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December 2019

'SCALD-ED' Block: Superficial Cutaneous Anesthesia in a Lateral Leg Distribution within the Emergency Department - A Case Series.

J Emerg Med 2019 Mar 9;56(3):282-287. Epub 2019 Jan 9.

Department of Emergency Medicine, Rutgers New Jersey Medical School, Newark, New Jersey.

Background: In the midst of a nationwide opioid epidemic, focus has been placed on identifying and utilizing safe, effective opioid-free analgesic alternatives. Lower-extremity peripheral nerve blockades are common and often involve both motor and sensory anesthesia, resulting in leg weakness and ambulatory difficulty. The aim of this case report is to describe an ultrasound-guided peripheral nerve block technique (superficial cutaneous anesthesia in a lateral (leg) distribution within the emergency department ['SCALD-ED' block]) that provides motor-sparing, purely sensory anesthesia after a superficial injury to the lateral leg in patients presenting to the emergency department. Read More

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Anti-neurofascin autoantibody and demyelination.

Neurochem Int 2019 11 22;130:104360. Epub 2018 Dec 22.

Department of Neurology, Neurological Institute, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.

Demyelination diseases involving the central and peripheral nervous systems are etiologically heterogeneous with both cell-mediated and humoral immunities playing pathogenic roles. Recently, autoantibodies against nodal and paranodal proteins, such as neurofascin186 (NF186), neurofascin155 (NF155), contactin-1 (CNTN1), contactin-associated protein 1 (CASPR1) and gliomedin, have been discovered in not only chronic demyelinating conditions, such as multiple sclerosis (MS) and chronic inflammatory demyelinating polyradiculoneuropathy, but also in acute demyelinating conditions, such as Guillain-Barré syndrome. Only a minority of these patients harbor anti-nodal/paranodal protein antibodies; however, these autoantibodies, especially IgG4 subclass autoantibodies to paranodal proteins, are associated with unique features and these conditions are collectively termed nodopathy or paranodopathy. Read More

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November 2019

Very Early Neurophysiological Study in Guillain-Barre Syndrome.

Eur Neurol 2018 22;80(1-2):100-105. Epub 2018 Oct 22.

Department of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an,

Purpose: The diagnosis of Guillain-Barre syndrome (GBS) in the very early stage may be challenging. Our aim was to report the neurophysiological abnormalities in GBS within 4 days of clinical onset. We expected that GBS will be diagnosed by the assistance of neurophysiological study in the very early stage. Read More

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January 2019

Peripheral neuropathy in Tangier disease: A literature review and assessment.

J Peripher Nerv Syst 2018 Jun 8;23(2):88-98. Epub 2018 May 8.

Department of Molecular Medicine, Bakirkoy Dr. Sadi Konuk Research and Training Hospital, Istanbul, Turkey.

Tangier disease (TD) (OMIM#205400) is a rare cause of inherited metabolic neuropathies characterized by marked deficiency of high-density lipoproteins and accumulation of cholesterol esters in various tissue resulting from reverse cholesterol transport deficiency. We report a case of a patient with TD with multifocal demyelinating neuropathy with conduction block who presents with winging scapula, tongue, and asymmetric extremity weakness. We also present a review of all studies published from 1960 to 2017 regarding peripheral neuropathy in TD. Read More

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Guillain-Barré Syndrome.

Peter D Donofrio

Continuum (Minneap Minn) 2017 Oct;23(5, Peripheral Nerve and Motor Neuron Disorders):1295-1309

Purpose Of Review: This article reviews the current state of Guillain-Barré syndrome (GBS), including its clinical presentation, evaluation, pathophysiology, and treatment.

Recent Findings: GBS is an acute/subacute-onset polyradiculoneuropathy typically presenting with sensory symptoms and weakness over several days, often leading to quadriparesis. Approximately 70% of patients report a recent preceding upper or lower respiratory tract infection or gastrointestinal illness. Read More

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October 2017

Ultrasound-guided therapeutic injections for neural pathology about the foot and ankle: a 4 year retrospective review.

Skeletal Radiol 2017 Jun 16;46(6):795-803. Epub 2017 Mar 16.

Center for Musculoskeletal Care, New York University Langone Medical Center, New York, NY, USA.

Objective: To describe a 4-year clinical experience with ultrasound-guided therapeutic perineural injections of peripheral nerves about the foot and ankle.

Materials And Methods: Retrospective analysis of foot and ankle perineural injections performed between January 2012 and August 2016. Demographics, clinical indications, presence of structural pathology, immediate and interval pain relief, as well as complications were recorded. Read More

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The mechanistic basis for photobiomodulation therapy of neuropathic pain by near infrared laser light.

Lasers Surg Med 2017 07 11;49(5):516-524. Epub 2017 Jan 11.

Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814.

Background And Objective: Various irradiances have been reported to be beneficial for the treatment of neuropathic pain with near infrared light. However, the mechanistic basis for the beneficial outcomes may vary based on the level of irradiance or fluence rate used. Using in vivo and in vitro experimental models, this study determined the mechanistic basis of photobiomodulation therapy (PBMT) for the treatment of neuropathic pain using a high irradiance. Read More

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Dexmedetomidine Added to Local Anesthetic Mixture of Lidocaine and Ropivacaine Enhances Onset and Prolongs Duration of a Popliteal Approach to Sciatic Nerve Blockade.

Clin Ther 2017 Jan 10;39(1):89-97.e1. Epub 2016 Dec 10.

Department of Anaesthesiology, First Affiliated Hospital, Wenzhou Medical University, Zhejiang, China. Electronic address:

Purpose: A literature review of multiple clinical studies on mixing additives to improve pharmacologic limitation of local anesthetics during peripheral nerve blockade revealed inconsistency in success rates and various adverse effects. Animal research on dexmedetomidine as an adjuvant on the other hand has promising results, with evidence of minimum unwanted results. This randomized, double-blinded, contrastable observational study examined the efficacy of adding dexmedetomidine to a mixture of lidocaine plus ropivacaine during popliteal sciatic nerve blockade (PSNB). Read More

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January 2017

[Clinical and electrophysiological characteristics and therapeutic analysis of 9 patients with Lewis-Sumner syndrome].

Zhonghua Yi Xue Za Zhi 2016 Mar;96(11):859-62

Department of Neurology, Peking University Third Hospital, Beijing 100191, China.

Objective: To investigate the clinical characteristics, electrophysiological findings and treatment response of Lewis-Sumner syndrome (LSS).

Methods: Data of nine patients with LSS, who were diagnosed and treated from May 2008 to August 2014 in Department of Neurology, Peking University Third Hospital, were analyzed retrospectively, including clinical features, electrophysiological studies, pathological characteristics, therapy and follow up.

Results: The nine cases included seven males and two females, with the average age being 29 years old (18-64 years old). Read More

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Workup and Management of Persistent Neuralgia following Nerve Block.

Case Rep Anesthesiol 2016 19;2016:9863492. Epub 2016 Jan 19.

University of California San Francisco School of Medicine, San Francisco, CA, USA.

Neurological injuries following peripheral nerve blocks are a relatively rare yet potentially devastating complication depending on the type of lesion, affected extremity, and duration of symptoms. Medical management continues to be the treatment modality of choice with multimodal nonopioid analgesics as the cornerstone of this therapy. We report the case of a 28-year-old man who developed a clinical common peroneal and lateral sural cutaneous neuropathy following an uncomplicated popliteal sciatic nerve block. Read More

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February 2016

N-hexane neuropathy with vertigo and cold allodynia in a silk screen printer: A case study.

Int J Occup Med Environ Health 2015 ;28(5):915-9

Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India (Department of Neurology).

N-hexane neuropathy is an occupational disease caused by exposure to n-hexane, which is used as a solvent in silk screen printing. Here, we describe a 35-year-old man, a silk screen printer by profession, who presented with dizziness, distal swelling of both lower limbs for 10 months and tingling and burning sensation in both feet for 9.5 months along with cold allodynia. Read More

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December 2016

Nerve conduction block in diabetic rats using high-intensity focused ultrasound for analgesic applications.

Br J Anaesth 2015 May 16;114(5):840-6. Epub 2015 Jan 16.

Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Zhunan, Taiwan

Background: Nerve conduction block using high-intensity focused ultrasound (HIFU) has been conducted with nerves of mixed fibres in normal animal models. This study tested the feasibility and safety of HIFU for sensory nerve conduction block in diabetic neuropathic nerves to determine its potential for pain relief.

Methods: Diabetes was induced in Sprague-Dawley rats using streptozotocin, and HIFU at 2. Read More

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Leprosy neuropathy evaluated by NCS is independent of the patient's infectious state.

Clin Neurol Neurosurg 2015 Apr 12;131:5-10. Epub 2015 Jan 12.

Leprosy Laboratory, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, RJ, Brazil.

Introduction: Leprosy causes nerve injury, which mimics clinical and neurophysiological conditions, rendering it an excellent model of peripheral neuropathy.

Methods: A retrospective study including 822 nerve conduction studies (NCS) of 509 patients was developed to appraise the electrophysiological pattern of leprosy neuropathy. NCS of motor and sensory nerves performed before, during, and after multidrug therapy (MDT) were analyzed. Read More

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Contribution of the sural nerve to postural stability and cutaneous sensation of the lower limb.

Foot Ankle Int 2015 Apr 19;36(4):450-6. Epub 2014 Dec 19.

Department of Podiatry, Faculty of Health Sciences, La Trobe University, Bundoora, Victoria, Australia

Background: The sural nerve is a cutaneous nerve of the lower limb that innervates the posterolateral aspect of the lower leg, ankle, and foot. Considering this pattern, it is plausible that it contributes to the maintenance of postural stability. However, the implications of sensory loss following sural nerve injury have yet to be thoroughly investigated. Read More

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High-intensity focused ultrasound attenuates neural responses of sciatic nerves isolated from normal or neuropathic rats.

Ultrasound Med Biol 2015 Jan 15;41(1):132-42. Epub 2014 Nov 15.

Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Zhunan, Taiwan. Electronic address:

Patients with diabetic neuropathy often have neuropathic pain. The purpose of our work was to investigate the effects of high-intensity focused ultrasound (HIFU) on the conduction block of normal and neuropathic nerves for soothing pain. Adult male Sprague-Dawley rats were used, and diabetes was induced by streptozotocin injection. Read More

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January 2015

Comparison of electrophysiological findings in axonal and demyelinating Guillain-Barre syndrome.

Iran J Neurol 2014 Jul;13(3):138-43

Department of Neurology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Background: Incidence and predominant subtype of Guillain-Barre syndrome (GBS) differs geographically. Electrophysiology has an important role in early diagnosis and prediction of prognosis. This study is conducted to determine the frequent subtype of GBS in a large group of patients in Iran and compare nerve conduction studies in axonal and demyelinating forms of GBS. Read More

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